Lhcgr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lhcgr
Entrez Gene ID	25477
Full Name	luteinizing hormone/choriogonadotropin receptor
Synonyms	LH/CG-R,LSH-R,LSHR,Lhr
General protein information	Preferred Names luteinizing hormone/choriogonadotropin receptor Names lutropin-choriogonadotropic hormone receptor LH receptor LH/CG receptor luteinizing hormone receptor luteinizing hormone/chorionic gonadotropin receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q12
Summary	for both luteinizing hormone and choriogonadotropin; involved in reproductive development and function [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012978.1	NP_037110.1	lutropin-choriogonadotropic hormone receptor precursor

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	LHCGR	XP_001114090.1
Bos taurus (cattle)	LHCGR	NP_776806.1
Drosophila melanogaster (fruit fly)	Lgr1	NP_524393.2
Homo sapiens (human)	LHCGR	NP_000224.2
Rattus norvegicus (Norway rat)	Lhcgr	NP_037110.1
Xenopus tropicalis (tropical clawed frog)	lhcgr	XP_002935423.2
Anopheles gambiae (African malaria mosquito)	GPRFSH	XP_309589.2
Canis lupus familiaris (dog)	LHCGR	XP_538486.2
Gallus gallus (chicken)	LHCGR	NP_990267.1
Danio rerio (zebrafish)	lhcgr	NP_991188.1
Caenorhabditis elegans (roundworm)	fshr-1	NP_505548.1
Mus musculus (house mouse)	Lhcgr	NP_038610.1
Pan troglodytes (chimpanzee)	LHCGR	XP_003309053.1

Gene Ontology
Bibliography

Related articles in PubMed

LHCGR Expression During Follicle Stimulating Hormone-Induced Follicle Growth Is Negatively Regulated by Eukaryotic Initiation Factor 5A.
Gulappa T, Menon B, Menon KMJ
Endocrinology158(8)2672-2679(2017 08)

Molecular regulation of LHCGR expression by miR-122 during follicle growth in the rat ovary.
Menon B, Gulappa T, Menon KM
Molecular and cellular endocrinology44281-89(2017 02)

miR-122 Regulates LH Receptor Expression by Activating Sterol Response Element Binding Protein in Rat Ovaries.
Menon B, Gulappa T, Menon KM
Endocrinology156(9)3370-80(2015 Sep)

TNF-α Suppressed FSH-Induced LH Receptor Expression Through Transcriptional Regulation in Rat Granulosa Cells.
Nakao K, Kishi H, Imai F, Suwa H, Hirakawa T, Minegishi T
Endocrinology156(9)3192-202(2015 Sep)

Hypusination of eukaryotic initiation factor 5A via cAMP-PKA-ERK1/2 pathway is required for ligand-induced downregulation of LH receptor mRNA expression in the ovary.
Gulappa T, Menon B, Menon KM
Molecular and cellular endocrinology41390-5(2015 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lhcgr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lhcgr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13582	NM_012978.1 Latest version!	Rattus norvegicus luteinizing hormone/choriogonadotropin receptor (Lhcgr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lhcgr ( NM_012978.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037110.1 Rattus norvegicus luteinizing hormone/choriogonadotropin receptor (Lhcgr), mRNA.

Price & Availability↑

CloneID	ORa13582
Clone ID Related Accession (Same CDS sequence)	NM_012978.1
Accession Version	NM_012978.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2103bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569081600000
Organism	Rattus norvegicus(Norway rat)
Product	lutropin-choriogonadotropic hormone receptor precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M26199.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M26199.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689601, SAMEA2689604 [ECO:0000350] ##Evidence-Data-END##

ATGGGGCGGC GAGTCCCAGC TCTGAGACAG CTGCTGGTGC TGGCAGTGCT GCTGCTGAAG 
CCTTCACAGC TGCAGTCCCG AGAGCTGTCA GGGTCGCGCT GCCCCGAGCC CTGCGACTGC 
GCACCGGATG GCGCCCTGCG CTGTCCTGGC CCTCGAGCCG GCCTCGCCAG ACTATCTCTC 
ACCTATCTCC CTGTCAAAGT AATTCCATCA CAAGCTTTCA GGGGACTTAA TGAGGTCGTA 
AAAATTGAAA TCTCTCAGAG TGATTCCCTG GAAAGGATAG AAGCTAATGC CTTTGACAAC 
CTCCTCAATT TGTCTGAACT ACTGATCCAG AACACCAAAA ACCTGCTATA CATTGAACCT 
GGTGCTTTTA CAAACCTCCC TCGGTTAAAA TACCTGAGCA TCTGTAACAC AGGCATCCGA 
ACCCTTCCAG ATGTTACGAA GATCTCCTCC TCTGAATTTA ATTTCATTCT GGAAATCTGT 
GATAACTTAC ACATAACCAC CATACCCGGG AATGCTTTCC AAGGGATGAA TAACGAGTCT 
GTCACACTAA AACTGTATGG AAATGGATTT GAAGAAGTAC AAAGCCATGC ATTCAATGGG 
ACGACTCTAA TCTCGCTGGA GCTAAAAGAA AACATCTACC TGGAGAAGAT GCACAGTGGA 
GCCTTCCAGG GGGCCACGGG GCCCAGCATC CTGGATATTT CTTCCACCAA ATTGCAGGCC 
CTGCCGAGCC ACGGGCTGGA GTCCATTCAG ACGCTCATCG CCCTGTCTTC CTACTCACTG 
AAAACACTGC CCTCCAAAGA AAAATTCACG AGCCTCCTGG TCGCCACGCT GACCTACCCC 
AGCCACTGCT GCGCCTTCAG GAATTTGCCG AAGAAAGAAC AGAATTTTTC ATTTTCCATT 
TTTGAAAACT TCTCCAAACA ATGCGAAAGC ACAGTTAGAA AAGCAGATAA CGAGACGCTT 
TATTCCGCCA TCTTTGAGGA GAATGAACTC AGTGGCTGGG ATTATGATTA TGGCTTCTGT 
TCACCCAAGA CACTCCAATG TGCTCCAGAA CCAGATGCTT TCAACCCCTG TGAAGATATT 
ATGGGCTATG CCTTCCTTAG GGTCCTGATT TGGCTGATTA ATATACTAGC CATCTTTGGC 
AACCTGACAG TCCTCTTTGT TCTCCTGACC AGTCGTTATA AACTGACAGT GCCCCGCTTC 
CTCATGTGTA ATCTCTCCTT TGCAGACTTT TGCATGGGGC TCTACCTGCT GCTCATTGCC 
TCCGTGGACT CCCAAACAAA AGGCCAGTAC TATAACCACG CCATAGACTG GCAGACAGGG 
AGTGGCTGCG GTGCAGCTGG CTTCTTTACT GTGTTTGCCA GTGAACTCTC TGTCTACACC 
CTGACGGTTA TCACCCTGGA AAGGTGGCAC ACCATCACCT ATGCTGTACA GCTAGACCAA 
AAGCTAAGAC TGAGGCATGC CATCCCAATT ATGCTCGGAG GATGGCTCTT TTCTACGCTG 
ATCGCCACGA TGCCCCTTGT GGGTATCAGC AATTACATGA AGGTCAGCAT CTGCCTCCCC 
ATGGATGTGG AATCCACTCT GTCCCAAGTC TACATATTAT CCATCTTAAT CCTCAACGTG 
GTGGCCTTCG TCGTCATCTG TGCTTGCTAC ATTAGGATCT ACTTTGCAGT TCAAAATCCA 
GAGCTGACAG CTCCTAACAA GGACACAAAA ATTGCTAAGA AGATGGCCAT CCTCATCTTC 
ACAGACTTCA CGTGCATGGC GCCCATCTCT TTCTTTGCCA TCTCGGCTGC CTTCAAAGTG 
CCCCTTATCA CTGTCACCAA CTCGAAAATC TTACTGGTCC TTTTTTATCC TGTCAATTCT 
TGTGCCAATC CATTTCTGTA TGCGATCTTC ACGAAGGCGT TTCAGAGAGA TTTCCTTCTG 
CTGCTGAGCC GATTCGGCTG CTGTAAACGC CGGGCGGAGC TTTACAGAAG GAAGGAATTT 
TCTGCATATA CTTCCAACTG CAAAAATGGC TTCCCAGGAG CAAGTAAGCC GTCCCAGGCT 
ACCCTGAAGT TGTCCACAGT GCACTGTCAA CAGCCCATAC CACCGAGAGC GTTAACTCAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037110.1
CDS	44..2146
Translation	MGRRVPALRQLLVLAVLLLKPSQLQSRELSGSRCPEPCDCAPDGALRCPGPRAGLARLSLTYLPVKVIPSQAFRGLNEVVKIEISQSDSLERIEANAFDNLLNLSELLIQNTKNLLYIEPGAFTNLPRLKYLSICNTGIRTLPDVTKISSSEFNFILEICDNLHITTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAFNGTTLISLELKENIYLEKMHSGAFQGATGPSILDISSTKLQALPSHGLESIQTLIALSSYSLKTLPSKEKFTSLLVATLTYPSHCCAFRNLPKKEQNFSFSIFENFSKQCESTVRKADNETLYSAIFEENELSGWDYDYGFCSPKTLQCAPEPDAFNPCEDIMGYAFLRVLIWLINILAIFGNLTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCGAAGFFTVFASELSVYTLTVITLERWHTITYAVQLDQKLRLRHAIPIMLGGWLFSTLIATMPLVGISNYMKVSICLPMDVESTLSQVYILSILILNVVAFVVICACYIRIYFAVQNPELTAPNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKILLVLFYPVNSCANPFLYAIFTKAFQRDFLLLLSRFGCCKRRAELYRRKEFSAYTSNCKNGFPGASKPSQATLKLSTVHCQQPIPPRALTH

Target ORF information:

RefSeq Version	NM_012978.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus luteinizing hormone/choriogonadotropin receptor (Lhcgr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012978.1

ORF Insert Sequence:

ATGGGGCGGC GAGTCCCAGC TCTGAGACAG CTGCTGGTGC TGGCAGTGCT GCTGCTGAAG 
CCTTCACAGC TGCAGTCCCG AGAGCTGTCA GGGTCGCGCT GCCCCGAGCC CTGCGACTGC 
GCACCGGATG GCGCCCTGCG CTGTCCTGGC CCTCGAGCCG GCCTCGCCAG ACTATCTCTC 
ACCTATCTCC CTGTCAAAGT AATTCCATCA CAAGCTTTCA GGGGACTTAA TGAGGTCGTA 
AAAATTGAAA TCTCTCAGAG TGATTCCCTG GAAAGGATAG AAGCTAATGC CTTTGACAAC 
CTCCTCAATT TGTCTGAACT ACTGATCCAG AACACCAAAA ACCTGCTATA CATTGAACCT 
GGTGCTTTTA CAAACCTCCC TCGGTTAAAA TACCTGAGCA TCTGTAACAC AGGCATCCGA 
ACCCTTCCAG ATGTTACGAA GATCTCCTCC TCTGAATTTA ATTTCATTCT GGAAATCTGT 
GATAACTTAC ACATAACCAC CATACCCGGG AATGCTTTCC AAGGGATGAA TAACGAGTCT 
GTCACACTAA AACTGTATGG AAATGGATTT GAAGAAGTAC AAAGCCATGC ATTCAATGGG 
ACGACTCTAA TCTCGCTGGA GCTAAAAGAA AACATCTACC TGGAGAAGAT GCACAGTGGA 
GCCTTCCAGG GGGCCACGGG GCCCAGCATC CTGGATATTT CTTCCACCAA ATTGCAGGCC 
CTGCCGAGCC ACGGGCTGGA GTCCATTCAG ACGCTCATCG CCCTGTCTTC CTACTCACTG 
AAAACACTGC CCTCCAAAGA AAAATTCACG AGCCTCCTGG TCGCCACGCT GACCTACCCC 
AGCCACTGCT GCGCCTTCAG GAATTTGCCG AAGAAAGAAC AGAATTTTTC ATTTTCCATT 
TTTGAAAACT TCTCCAAACA ATGCGAAAGC ACAGTTAGAA AAGCAGATAA CGAGACGCTT 
TATTCCGCCA TCTTTGAGGA GAATGAACTC AGTGGCTGGG ATTATGATTA TGGCTTCTGT 
TCACCCAAGA CACTCCAATG TGCTCCAGAA CCAGATGCTT TCAACCCCTG TGAAGATATT 
ATGGGCTATG CCTTCCTTAG GGTCCTGATT TGGCTGATTA ATATACTAGC CATCTTTGGC 
AACCTGACAG TCCTCTTTGT TCTCCTGACC AGTCGTTATA AACTGACAGT GCCCCGCTTC 
CTCATGTGTA ATCTCTCCTT TGCAGACTTT TGCATGGGGC TCTACCTGCT GCTCATTGCC 
TCCGTGGACT CCCAAACAAA AGGCCAGTAC TATAACCACG CCATAGACTG GCAGACAGGG 
AGTGGCTGCG GTGCAGCTGG CTTCTTTACT GTGTTTGCCA GTGAACTCTC TGTCTACACC 
CTGACGGTTA TCACCCTGGA AAGGTGGCAC ACCATCACCT ATGCTGTACA GCTAGACCAA 
AAGCTAAGAC TGAGGCATGC CATCCCAATT ATGCTCGGAG GATGGCTCTT TTCTACGCTG 
ATCGCCACGA TGCCCCTTGT GGGTATCAGC AATTACATGA AGGTCAGCAT CTGCCTCCCC 
ATGGATGTGG AATCCACTCT GTCCCAAGTC TACATATTAT CCATCTTAAT CCTCAACGTG 
GTGGCCTTCG TCGTCATCTG TGCTTGCTAC ATTAGGATCT ACTTTGCAGT TCAAAATCCA 
GAGCTGACAG CTCCTAACAA GGACACAAAA ATTGCTAAGA AGATGGCCAT CCTCATCTTC 
ACAGACTTCA CGTGCATGGC GCCCATCTCT TTCTTTGCCA TCTCGGCTGC CTTCAAAGTG 
CCCCTTATCA CTGTCACCAA CTCGAAAATC TTACTGGTCC TTTTTTATCC TGTCAATTCT 
TGTGCCAATC CATTTCTGTA TGCGATCTTC ACGAAGGCGT TTCAGAGAGA TTTCCTTCTG 
CTGCTGAGCC GATTCGGCTG CTGTAAACGC CGGGCGGAGC TTTACAGAAG GAAGGAATTT 
TCTGCATATA CTTCCAACTG CAAAAATGGC TTCCCAGGAG CAAGTAAGCC GTCCCAGGCT 
ACCCTGAAGT TGTCCACAGT GCACTGTCAA CAGCCCATAC CACCGAGAGC GTTAACTCAC 
TAG