Fbxo6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fbxo6
Entrez Gene ID	192351
Full Name	F-box protein 6
Synonyms	Fbg2,Fbxo6b
General protein information	Preferred Names F-box protein 6 Names F-box only protein 6 F-box only protein 6 b F-box only protein 6b F-box protein that recognizes sugar chains 2 F-box/G-domain protein 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36
Summary	binds proteins targeted for ubiquitination; functions in the differentiation/proliferation of hepatocytes [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006239375.3	XP_006239437.1	F-box only protein 6 isoform X1
XM_006239372.3	XP_006239434.1	F-box only protein 6 isoform X1
XM_006239374.3	XP_006239436.1	F-box only protein 6 isoform X1
XM_006239373.3	XP_006239435.1	F-box only protein 6 isoform X1
NM_138917.3	NP_620272.3	F-box only protein 6

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FBXO6	NP_001233333.1
Macaca mulatta (Rhesus monkey)	LOC722740	XP_002802223.1
Danio rerio (zebrafish)	si:rp71-1k13.6	XP_005162152.1
Homo sapiens (human)	FBXO6	NP_060908.1
Danio rerio (zebrafish)	si:dkey-147f3.4	NP_001153111.1
Xenopus tropicalis (tropical clawed frog)	fbxo6	XP_004916183.1
Canis lupus familiaris (dog)	FBXO6	XP_005618058.1
Danio rerio (zebrafish)	zgc:100832	NP_001003542.1
Danio rerio (zebrafish)	zgc:153722	NP_001070044.1
Bos taurus (cattle)	FBXO6	NP_001029605.1
Danio rerio (zebrafish)	fbxo44	NP_001008577.1
Danio rerio (zebrafish)	zgc:114174	NP_001020352.1
Danio rerio (zebrafish)	zgc:114081	NP_001025364.1
Mus musculus (house mouse)	Fbxo6	NP_001157176.1
Rattus norvegicus (Norway rat)	Fbxo6	NP_620272.3
Gallus gallus (chicken)	FBXO6	XP_417649.2
Danio rerio (zebrafish)	zgc:173570	NP_001104672.1

Gene Ontology
Bibliography

Related articles in PubMed

Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps.
Groisman B, Shenkman M, Ron E, Lederkremer GZ
The Journal of biological chemistry286(2)1292-300(2011 Jan)

The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.
Zhang YW, Brognard J, Coughlin C, You Z, Dolled-Filhart M, Aslanian A, Manning G, Abraham RT, Hunter T
Molecular cell35(4)442-53(2009 Aug)

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.
Ebstein F, Lange N, Urban S, Seifert U, Krüger E, Kloetzel PM
The international journal of biochemistry & cell biology41(5)1205-15(2009 May)

Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates.
Yoshida Y, Adachi E, Fukiya K, Iwai K, Tanaka K
EMBO reports6(3)239-44(2005 Mar)

Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains.
Yoshida Y, Tokunaga F, Chiba T, Iwai K, Tanaka K, Tai T
The Journal of biological chemistry278(44)43877-84(2003 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fbxo6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fbxo6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa02022	NM_138917.3 Latest version!	Rattus norvegicus F-box protein 6 (Fbxo6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa02022	XM_006239374.3 Latest version!	Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa02022	XM_006239372.3 Latest version!	Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa02022	XM_006239373.3 Latest version!	Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa02022	XM_006239375.3 Latest version!	Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fbxo6 ( NM_138917.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_620272.3 Rattus norvegicus F-box protein 6 (Fbxo6), mRNA.

Price & Availability↑

CloneID	ORa02022
Clone ID Related Accession (Same CDS sequence)	XM_006239375.3 , XM_006239372.3 , XM_006239374.3 , XM_006239373.3 , NM_138917.3
Accession Version	NM_138917.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	F-box only protein 6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF393484.1. On Jun 10, 2007 this sequence version replaced NM_138917.2. ##Evidence-Data-START## Transcript exon combination :: AF393484.1, BC063148.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGTCAACA TCAACGAGCT GCCGGAGAAC ATTCTACTGG AACTGTTCAC CCACGTCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCAGCC TCTGGCGAGA CCTCATCGAT 
GTGATGACCC TCTGGAAGCG CAAGAGCCTT CGAGAGGGCT TTGTCACCAA AGACCGGGAC 
GAGCCTGTGG ATGACTGGAA GATCTTCTAT ATCCTGTGCA GTCTGCAAAG GAACCTCCTT 
CGGAACCCGT GTGCCGAAGA GAACCTGAGA TCATGGCGGA TAGACTCCAA TGGGGGAGAT 
GAGTGGAAGG TGGAGAGCCT CCCTGGGGAC CACGGCACAA GCTTTCCTGA CACCAAGGTC 
AAGAAGTATT TTGTCACCTC TTATGGGATG TGCCTCAAGT CCCAGATGGT GGACCTCAAA 
GCCGAGGGCT ACTCTGAAAA GCTGCTGGAC ACCGTTCGGC CGGACATTGT GGTTAAAGAC 
TGGTTTGCCC CACGAGCAGA CTGCGGCTGT ACCTATCACC TCCGGGTACA GCTGGCCTCT 
GCCGACTACA TTGTCCTAGC CTCCTTTGAG CCTCCGCCTG TGACCATCGA ACAGTGGAAT 
GACGCCAGCT GGCAAGAGAT CTCCCACACC TTCTCCAATT ACCCTCCTGG CGTCCGTCAC 
ATCCTTTTTC AACATGGGGG CAAGGACACA CAGTTCTGGA AAGGCTGGTA TGGTCCCCGT 
GTCACCAACA GCAGCATCAT CGTCAGCCAC AGGACAGCCA AGAACCCCGC CCCTGCCAGA 
ACTCTACCGG AGGAAGACAC TAGTAATAGG AGGAAGATAC TCAGCTTTGG CTCCTGGGAA 
GACCTAAGCC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620272.3
CDS	22..876
Translation	MVNINELPENILLELFTHVPAPQLLRNCRLVCSLWRDLIDVMTLWKRKSLREGFVTKDRDEPVDDWKIFYILCSLQRNLLRNPCAEENLRSWRIDSNGGDEWKVESLPGDHGTSFPDTKVKKYFVTSYGMCLKSQMVDLKAEGYSEKLLDTVRPDIVVKDWFAPRADCGCTYHLRVQLASADYIVLASFEPPPVTIEQWNDASWQEISHTFSNYPPGVRHILFQHGGKDTQFWKGWYGPRVTNSSIIVSHRTAKNPAPARTLPEEDTSNRRKILSFGSWEDLSP

Target ORF information:

RefSeq Version	NM_138917.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus F-box protein 6 (Fbxo6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138917.3

ORF Insert Sequence:

ATGGTCAACA TCAACGAGCT GCCGGAGAAC ATTCTACTGG AACTGTTCAC CCACGTCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCAGCC TCTGGCGAGA CCTCATCGAT 
GTGATGACCC TCTGGAAGCG CAAGAGCCTT CGAGAGGGCT TTGTCACCAA AGACCGGGAC 
GAGCCTGTGG ATGACTGGAA GATCTTCTAT ATCCTGTGCA GTCTGCAAAG GAACCTCCTT 
CGGAACCCGT GTGCCGAAGA GAACCTGAGA TCATGGCGGA TAGACTCCAA TGGGGGAGAT 
GAGTGGAAGG TGGAGAGCCT CCCTGGGGAC CACGGCACAA GCTTTCCTGA CACCAAGGTC 
AAGAAGTATT TTGTCACCTC TTATGGGATG TGCCTCAAGT CCCAGATGGT GGACCTCAAA 
GCCGAGGGCT ACTCTGAAAA GCTGCTGGAC ACCGTTCGGC CGGACATTGT GGTTAAAGAC 
TGGTTTGCCC CACGAGCAGA CTGCGGCTGT ACCTATCACC TCCGGGTACA GCTGGCCTCT 
GCCGACTACA TTGTCCTAGC CTCCTTTGAG CCTCCGCCTG TGACCATCGA ACAGTGGAAT 
GACGCCAGCT GGCAAGAGAT CTCCCACACC TTCTCCAATT ACCCTCCTGG CGTCCGTCAC 
ATCCTTTTTC AACATGGGGG CAAGGACACA CAGTTCTGGA AAGGCTGGTA TGGTCCCCGT 
GTCACCAACA GCAGCATCAT CGTCAGCCAC AGGACAGCCA AGAACCCCGC CCCTGCCAGA 
ACTCTACCGG AGGAAGACAC TAGTAATAGG AGGAAGATAC TCAGCTTTGG CTCCTGGGAA 
GACCTAAGCC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fbxo6 ( XM_006239375.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239437.1 Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa02022
Clone ID Related Accession (Same CDS sequence)	XM_006239375.3 , XM_006239372.3 , XM_006239374.3 , XM_006239373.3 , NM_138917.3
Accession Version	XM_006239375.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	F-box only protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239375.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCAACA TCAACGAGCT GCCGGAGAAC ATTCTACTGG AACTGTTCAC CCACGTCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCAGCC TCTGGCGAGA CCTCATCGAT 
GTGATGACCC TCTGGAAGCG CAAGAGCCTT CGAGAGGGCT TTGTCACCAA AGACCGGGAC 
GAGCCTGTGG ATGACTGGAA GATCTTCTAT ATCCTGTGCA GTCTGCAAAG GAACCTCCTT 
CGGAACCCGT GTGCCGAAGA GAACCTGAGA TCATGGCGGA TAGACTCCAA TGGGGGAGAT 
GAGTGGAAGG TGGAGAGCCT CCCTGGGGAC CACGGCACAA GCTTTCCTGA CACCAAGGTC 
AAGAAGTATT TTGTCACCTC TTATGGGATG TGCCTCAAGT CCCAGATGGT GGACCTCAAA 
GCCGAGGGCT ACTCTGAAAA GCTGCTGGAC ACCGTTCGGC CGGACATTGT GGTTAAAGAC 
TGGTTTGCCC CACGAGCAGA CTGCGGCTGT ACCTATCACC TCCGGGTACA GCTGGCCTCT 
GCCGACTACA TTGTCCTAGC CTCCTTTGAG CCTCCGCCTG TGACCATCGA ACAGTGGAAT 
GACGCCAGCT GGCAAGAGAT CTCCCACACC TTCTCCAATT ACCCTCCTGG CGTCCGTCAC 
ATCCTTTTTC AACATGGGGG CAAGGACACA CAGTTCTGGA AAGGCTGGTA TGGTCCCCGT 
GTCACCAACA GCAGCATCAT CGTCAGCCAC AGGACAGCCA AGAACCCCGC CCCTGCCAGA 
ACTCTACCGG AGGAAGACAC TAGTAATAGG AGGAAGATAC TCAGCTTTGG CTCCTGGGAA 
GACCTAAGCC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239437.1
CDS	193..1047
Translation	MVNINELPENILLELFTHVPAPQLLRNCRLVCSLWRDLIDVMTLWKRKSLREGFVTKDRDEPVDDWKIFYILCSLQRNLLRNPCAEENLRSWRIDSNGGDEWKVESLPGDHGTSFPDTKVKKYFVTSYGMCLKSQMVDLKAEGYSEKLLDTVRPDIVVKDWFAPRADCGCTYHLRVQLASADYIVLASFEPPPVTIEQWNDASWQEISHTFSNYPPGVRHILFQHGGKDTQFWKGWYGPRVTNSSIIVSHRTAKNPAPARTLPEEDTSNRRKILSFGSWEDLSP

Target ORF information:

RefSeq Version	XM_006239375.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239375.3

ORF Insert Sequence:

ATGGTCAACA TCAACGAGCT GCCGGAGAAC ATTCTACTGG AACTGTTCAC CCACGTCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCAGCC TCTGGCGAGA CCTCATCGAT 
GTGATGACCC TCTGGAAGCG CAAGAGCCTT CGAGAGGGCT TTGTCACCAA AGACCGGGAC 
GAGCCTGTGG ATGACTGGAA GATCTTCTAT ATCCTGTGCA GTCTGCAAAG GAACCTCCTT 
CGGAACCCGT GTGCCGAAGA GAACCTGAGA TCATGGCGGA TAGACTCCAA TGGGGGAGAT 
GAGTGGAAGG TGGAGAGCCT CCCTGGGGAC CACGGCACAA GCTTTCCTGA CACCAAGGTC 
AAGAAGTATT TTGTCACCTC TTATGGGATG TGCCTCAAGT CCCAGATGGT GGACCTCAAA 
GCCGAGGGCT ACTCTGAAAA GCTGCTGGAC ACCGTTCGGC CGGACATTGT GGTTAAAGAC 
TGGTTTGCCC CACGAGCAGA CTGCGGCTGT ACCTATCACC TCCGGGTACA GCTGGCCTCT 
GCCGACTACA TTGTCCTAGC CTCCTTTGAG CCTCCGCCTG TGACCATCGA ACAGTGGAAT 
GACGCCAGCT GGCAAGAGAT CTCCCACACC TTCTCCAATT ACCCTCCTGG CGTCCGTCAC 
ATCCTTTTTC AACATGGGGG CAAGGACACA CAGTTCTGGA AAGGCTGGTA TGGTCCCCGT 
GTCACCAACA GCAGCATCAT CGTCAGCCAC AGGACAGCCA AGAACCCCGC CCCTGCCAGA 
ACTCTACCGG AGGAAGACAC TAGTAATAGG AGGAAGATAC TCAGCTTTGG CTCCTGGGAA 
GACCTAAGCC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fbxo6 ( XM_006239372.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239434.1 Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa02022
Clone ID Related Accession (Same CDS sequence)	XM_006239375.3 , XM_006239372.3 , XM_006239374.3 , XM_006239373.3 , NM_138917.3
Accession Version	XM_006239372.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	F-box only protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239372.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCAACA TCAACGAGCT GCCGGAGAAC ATTCTACTGG AACTGTTCAC CCACGTCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCAGCC TCTGGCGAGA CCTCATCGAT 
GTGATGACCC TCTGGAAGCG CAAGAGCCTT CGAGAGGGCT TTGTCACCAA AGACCGGGAC 
GAGCCTGTGG ATGACTGGAA GATCTTCTAT ATCCTGTGCA GTCTGCAAAG GAACCTCCTT 
CGGAACCCGT GTGCCGAAGA GAACCTGAGA TCATGGCGGA TAGACTCCAA TGGGGGAGAT 
GAGTGGAAGG TGGAGAGCCT CCCTGGGGAC CACGGCACAA GCTTTCCTGA CACCAAGGTC 
AAGAAGTATT TTGTCACCTC TTATGGGATG TGCCTCAAGT CCCAGATGGT GGACCTCAAA 
GCCGAGGGCT ACTCTGAAAA GCTGCTGGAC ACCGTTCGGC CGGACATTGT GGTTAAAGAC 
TGGTTTGCCC CACGAGCAGA CTGCGGCTGT ACCTATCACC TCCGGGTACA GCTGGCCTCT 
GCCGACTACA TTGTCCTAGC CTCCTTTGAG CCTCCGCCTG TGACCATCGA ACAGTGGAAT 
GACGCCAGCT GGCAAGAGAT CTCCCACACC TTCTCCAATT ACCCTCCTGG CGTCCGTCAC 
ATCCTTTTTC AACATGGGGG CAAGGACACA CAGTTCTGGA AAGGCTGGTA TGGTCCCCGT 
GTCACCAACA GCAGCATCAT CGTCAGCCAC AGGACAGCCA AGAACCCCGC CCCTGCCAGA 
ACTCTACCGG AGGAAGACAC TAGTAATAGG AGGAAGATAC TCAGCTTTGG CTCCTGGGAA 
GACCTAAGCC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239434.1
CDS	333..1187
Translation	MVNINELPENILLELFTHVPAPQLLRNCRLVCSLWRDLIDVMTLWKRKSLREGFVTKDRDEPVDDWKIFYILCSLQRNLLRNPCAEENLRSWRIDSNGGDEWKVESLPGDHGTSFPDTKVKKYFVTSYGMCLKSQMVDLKAEGYSEKLLDTVRPDIVVKDWFAPRADCGCTYHLRVQLASADYIVLASFEPPPVTIEQWNDASWQEISHTFSNYPPGVRHILFQHGGKDTQFWKGWYGPRVTNSSIIVSHRTAKNPAPARTLPEEDTSNRRKILSFGSWEDLSP

Target ORF information:

RefSeq Version	XM_006239372.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239372.3

ORF Insert Sequence:

ATGGTCAACA TCAACGAGCT GCCGGAGAAC ATTCTACTGG AACTGTTCAC CCACGTCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCAGCC TCTGGCGAGA CCTCATCGAT 
GTGATGACCC TCTGGAAGCG CAAGAGCCTT CGAGAGGGCT TTGTCACCAA AGACCGGGAC 
GAGCCTGTGG ATGACTGGAA GATCTTCTAT ATCCTGTGCA GTCTGCAAAG GAACCTCCTT 
CGGAACCCGT GTGCCGAAGA GAACCTGAGA TCATGGCGGA TAGACTCCAA TGGGGGAGAT 
GAGTGGAAGG TGGAGAGCCT CCCTGGGGAC CACGGCACAA GCTTTCCTGA CACCAAGGTC 
AAGAAGTATT TTGTCACCTC TTATGGGATG TGCCTCAAGT CCCAGATGGT GGACCTCAAA 
GCCGAGGGCT ACTCTGAAAA GCTGCTGGAC ACCGTTCGGC CGGACATTGT GGTTAAAGAC 
TGGTTTGCCC CACGAGCAGA CTGCGGCTGT ACCTATCACC TCCGGGTACA GCTGGCCTCT 
GCCGACTACA TTGTCCTAGC CTCCTTTGAG CCTCCGCCTG TGACCATCGA ACAGTGGAAT 
GACGCCAGCT GGCAAGAGAT CTCCCACACC TTCTCCAATT ACCCTCCTGG CGTCCGTCAC 
ATCCTTTTTC AACATGGGGG CAAGGACACA CAGTTCTGGA AAGGCTGGTA TGGTCCCCGT 
GTCACCAACA GCAGCATCAT CGTCAGCCAC AGGACAGCCA AGAACCCCGC CCCTGCCAGA 
ACTCTACCGG AGGAAGACAC TAGTAATAGG AGGAAGATAC TCAGCTTTGG CTCCTGGGAA 
GACCTAAGCC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fbxo6 ( XM_006239374.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239436.1 Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa02022
Clone ID Related Accession (Same CDS sequence)	XM_006239375.3 , XM_006239372.3 , XM_006239374.3 , XM_006239373.3 , NM_138917.3
Accession Version	XM_006239374.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	F-box only protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239374.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCAACA TCAACGAGCT GCCGGAGAAC ATTCTACTGG AACTGTTCAC CCACGTCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCAGCC TCTGGCGAGA CCTCATCGAT 
GTGATGACCC TCTGGAAGCG CAAGAGCCTT CGAGAGGGCT TTGTCACCAA AGACCGGGAC 
GAGCCTGTGG ATGACTGGAA GATCTTCTAT ATCCTGTGCA GTCTGCAAAG GAACCTCCTT 
CGGAACCCGT GTGCCGAAGA GAACCTGAGA TCATGGCGGA TAGACTCCAA TGGGGGAGAT 
GAGTGGAAGG TGGAGAGCCT CCCTGGGGAC CACGGCACAA GCTTTCCTGA CACCAAGGTC 
AAGAAGTATT TTGTCACCTC TTATGGGATG TGCCTCAAGT CCCAGATGGT GGACCTCAAA 
GCCGAGGGCT ACTCTGAAAA GCTGCTGGAC ACCGTTCGGC CGGACATTGT GGTTAAAGAC 
TGGTTTGCCC CACGAGCAGA CTGCGGCTGT ACCTATCACC TCCGGGTACA GCTGGCCTCT 
GCCGACTACA TTGTCCTAGC CTCCTTTGAG CCTCCGCCTG TGACCATCGA ACAGTGGAAT 
GACGCCAGCT GGCAAGAGAT CTCCCACACC TTCTCCAATT ACCCTCCTGG CGTCCGTCAC 
ATCCTTTTTC AACATGGGGG CAAGGACACA CAGTTCTGGA AAGGCTGGTA TGGTCCCCGT 
GTCACCAACA GCAGCATCAT CGTCAGCCAC AGGACAGCCA AGAACCCCGC CCCTGCCAGA 
ACTCTACCGG AGGAAGACAC TAGTAATAGG AGGAAGATAC TCAGCTTTGG CTCCTGGGAA 
GACCTAAGCC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239436.1
CDS	189..1043
Translation	MVNINELPENILLELFTHVPAPQLLRNCRLVCSLWRDLIDVMTLWKRKSLREGFVTKDRDEPVDDWKIFYILCSLQRNLLRNPCAEENLRSWRIDSNGGDEWKVESLPGDHGTSFPDTKVKKYFVTSYGMCLKSQMVDLKAEGYSEKLLDTVRPDIVVKDWFAPRADCGCTYHLRVQLASADYIVLASFEPPPVTIEQWNDASWQEISHTFSNYPPGVRHILFQHGGKDTQFWKGWYGPRVTNSSIIVSHRTAKNPAPARTLPEEDTSNRRKILSFGSWEDLSP

Target ORF information:

RefSeq Version	XM_006239374.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239374.3

ORF Insert Sequence:

ATGGTCAACA TCAACGAGCT GCCGGAGAAC ATTCTACTGG AACTGTTCAC CCACGTCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCAGCC TCTGGCGAGA CCTCATCGAT 
GTGATGACCC TCTGGAAGCG CAAGAGCCTT CGAGAGGGCT TTGTCACCAA AGACCGGGAC 
GAGCCTGTGG ATGACTGGAA GATCTTCTAT ATCCTGTGCA GTCTGCAAAG GAACCTCCTT 
CGGAACCCGT GTGCCGAAGA GAACCTGAGA TCATGGCGGA TAGACTCCAA TGGGGGAGAT 
GAGTGGAAGG TGGAGAGCCT CCCTGGGGAC CACGGCACAA GCTTTCCTGA CACCAAGGTC 
AAGAAGTATT TTGTCACCTC TTATGGGATG TGCCTCAAGT CCCAGATGGT GGACCTCAAA 
GCCGAGGGCT ACTCTGAAAA GCTGCTGGAC ACCGTTCGGC CGGACATTGT GGTTAAAGAC 
TGGTTTGCCC CACGAGCAGA CTGCGGCTGT ACCTATCACC TCCGGGTACA GCTGGCCTCT 
GCCGACTACA TTGTCCTAGC CTCCTTTGAG CCTCCGCCTG TGACCATCGA ACAGTGGAAT 
GACGCCAGCT GGCAAGAGAT CTCCCACACC TTCTCCAATT ACCCTCCTGG CGTCCGTCAC 
ATCCTTTTTC AACATGGGGG CAAGGACACA CAGTTCTGGA AAGGCTGGTA TGGTCCCCGT 
GTCACCAACA GCAGCATCAT CGTCAGCCAC AGGACAGCCA AGAACCCCGC CCCTGCCAGA 
ACTCTACCGG AGGAAGACAC TAGTAATAGG AGGAAGATAC TCAGCTTTGG CTCCTGGGAA 
GACCTAAGCC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fbxo6 ( XM_006239373.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239435.1 Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X2, mRNA.

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CloneID	ORa02022
Clone ID Related Accession (Same CDS sequence)	XM_006239375.3 , XM_006239372.3 , XM_006239374.3 , XM_006239373.3 , NM_138917.3
Accession Version	XM_006239373.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	F-box only protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239373.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCAACA TCAACGAGCT GCCGGAGAAC ATTCTACTGG AACTGTTCAC CCACGTCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCAGCC TCTGGCGAGA CCTCATCGAT 
GTGATGACCC TCTGGAAGCG CAAGAGCCTT CGAGAGGGCT TTGTCACCAA AGACCGGGAC 
GAGCCTGTGG ATGACTGGAA GATCTTCTAT ATCCTGTGCA GTCTGCAAAG GAACCTCCTT 
CGGAACCCGT GTGCCGAAGA GAACCTGAGA TCATGGCGGA TAGACTCCAA TGGGGGAGAT 
GAGTGGAAGG TGGAGAGCCT CCCTGGGGAC CACGGCACAA GCTTTCCTGA CACCAAGGTC 
AAGAAGTATT TTGTCACCTC TTATGGGATG TGCCTCAAGT CCCAGATGGT GGACCTCAAA 
GCCGAGGGCT ACTCTGAAAA GCTGCTGGAC ACCGTTCGGC CGGACATTGT GGTTAAAGAC 
TGGTTTGCCC CACGAGCAGA CTGCGGCTGT ACCTATCACC TCCGGGTACA GCTGGCCTCT 
GCCGACTACA TTGTCCTAGC CTCCTTTGAG CCTCCGCCTG TGACCATCGA ACAGTGGAAT 
GACGCCAGCT GGCAAGAGAT CTCCCACACC TTCTCCAATT ACCCTCCTGG CGTCCGTCAC 
ATCCTTTTTC AACATGGGGG CAAGGACACA CAGTTCTGGA AAGGCTGGTA TGGTCCCCGT 
GTCACCAACA GCAGCATCAT CGTCAGCCAC AGGACAGCCA AGAACCCCGC CCCTGCCAGA 
ACTCTACCGG AGGAAGACAC TAGTAATAGG AGGAAGATAC TCAGCTTTGG CTCCTGGGAA 
GACCTAAGCC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239435.1
CDS	266..1120
Translation	MVNINELPENILLELFTHVPAPQLLRNCRLVCSLWRDLIDVMTLWKRKSLREGFVTKDRDEPVDDWKIFYILCSLQRNLLRNPCAEENLRSWRIDSNGGDEWKVESLPGDHGTSFPDTKVKKYFVTSYGMCLKSQMVDLKAEGYSEKLLDTVRPDIVVKDWFAPRADCGCTYHLRVQLASADYIVLASFEPPPVTIEQWNDASWQEISHTFSNYPPGVRHILFQHGGKDTQFWKGWYGPRVTNSSIIVSHRTAKNPAPARTLPEEDTSNRRKILSFGSWEDLSP

Target ORF information:

RefSeq Version	XM_006239373.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus F-box protein 6 (Fbxo6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239373.3

ORF Insert Sequence:

ATGGTCAACA TCAACGAGCT GCCGGAGAAC ATTCTACTGG AACTGTTCAC CCACGTCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCAGCC TCTGGCGAGA CCTCATCGAT 
GTGATGACCC TCTGGAAGCG CAAGAGCCTT CGAGAGGGCT TTGTCACCAA AGACCGGGAC 
GAGCCTGTGG ATGACTGGAA GATCTTCTAT ATCCTGTGCA GTCTGCAAAG GAACCTCCTT 
CGGAACCCGT GTGCCGAAGA GAACCTGAGA TCATGGCGGA TAGACTCCAA TGGGGGAGAT 
GAGTGGAAGG TGGAGAGCCT CCCTGGGGAC CACGGCACAA GCTTTCCTGA CACCAAGGTC 
AAGAAGTATT TTGTCACCTC TTATGGGATG TGCCTCAAGT CCCAGATGGT GGACCTCAAA 
GCCGAGGGCT ACTCTGAAAA GCTGCTGGAC ACCGTTCGGC CGGACATTGT GGTTAAAGAC 
TGGTTTGCCC CACGAGCAGA CTGCGGCTGT ACCTATCACC TCCGGGTACA GCTGGCCTCT 
GCCGACTACA TTGTCCTAGC CTCCTTTGAG CCTCCGCCTG TGACCATCGA ACAGTGGAAT 
GACGCCAGCT GGCAAGAGAT CTCCCACACC TTCTCCAATT ACCCTCCTGG CGTCCGTCAC 
ATCCTTTTTC AACATGGGGG CAAGGACACA CAGTTCTGGA AAGGCTGGTA TGGTCCCCGT 
GTCACCAACA GCAGCATCAT CGTCAGCCAC AGGACAGCCA AGAACCCCGC CCCTGCCAGA 
ACTCTACCGG AGGAAGACAC TAGTAATAGG AGGAAGATAC TCAGCTTTGG CTCCTGGGAA 
GACCTAAGCC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps.
The Journal of biological chemistry286(2)1292-300(2011 Jan)
Groisman B,Shenkman M,Ron E,Lederkremer GZ

The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.
Molecular cell35(4)442-53(2009 Aug)
Zhang YW,Brognard J,Coughlin C,You Z,Dolled-Filhart M,Aslanian A,Manning G,Abraham RT,Hunter T

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.
The international journal of biochemistry & cell biology41(5)1205-15(2009 May)
Ebstein F,Lange N,Urban S,Seifert U,Krüger E,Kloetzel PM

Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates.
EMBO reports6(3)239-44(2005 Mar)
Yoshida Y,Adachi E,Fukiya K,Iwai K,Tanaka K

Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains.
The Journal of biological chemistry278(44)43877-84(2003 Oct)
Yoshida Y,Tokunaga F,Chiba T,Iwai K,Tanaka K,Tai T

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Fbxo6 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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