Il2rg cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Il2rg
Entrez Gene ID	140924
Full Name	interleukin 2 receptor subunit gamma
Synonyms	Ab2-183,Cd132
General protein information	Preferred Names interleukin 2 receptor subunit gamma Names cytokine receptor common subunit gamma interleukin 2 receptor, gamma (severe combined immunodeficiency)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq22
Summary	cytokine receptor which contributes to ligand binding and signal transduction [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017601899.1	XP_017457388.1	cytokine receptor common subunit gamma isoform X1
NM_080889.1	NP_543165.1	cytokine receptor common subunit gamma precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Il2rg	NP_543165.1
Gallus gallus (chicken)	IL2RG	NP_989858.1
Danio rerio (zebrafish)	il2rgb	NP_001116522.1
Canis lupus familiaris (dog)	IL2RG	NP_001003201.1
Pan troglodytes (chimpanzee)	LOC101059843	XP_003954068.1
Macaca mulatta (Rhesus monkey)	IL2RG	NP_001030606.1
Homo sapiens (human)	IL2RG	NP_000197.1
Mus musculus (house mouse)	Il2rg	NP_038591.1
Danio rerio (zebrafish)	il2rga	NP_001121743.1
Xenopus tropicalis (tropical clawed frog)	LOC100492995	XP_002934932.1
Bos taurus (cattle)	IL2RG	NP_776784.1

Gene Ontology
Bibliography

Related articles in PubMed

Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models.
Ménoret S, Ouisse LH, Tesson L, Delbos F, Garnier D, Remy S, Usal C, Concordet JP, Giovannangeli C, Chenouard V, Brusselle L, Merieau E, Nerrière-Daguin V, Duteille F, Bellier-Waast F, Fraichard A, Nguyen TH, Anegon I
Transplantation102(8)1271-1278(2018 08)

Conditionals by inversion provide a universal method for the generation of conditional alleles.
Economides AN, Frendewey D, Yang P, Dominguez MG, Dore AT, Lobov IB, Persaud T, Rojas J, McClain J, Lengyel P, Droguett G, Chernomorsky R, Stevens S, Auerbach W, Dechiara TM, Pouyemirou W, Cruz JM Jr, Feeley K, Mellis IA, Yasenchack J, Hatsell SJ, Xie L, Latres E, Huang L, Zhang Y, Pefanis E, Skokos D, Deckelbaum RA, Croll SD, Davis S, Valenzuela DM, Gale NW, Murphy AJ, Yancopoulos GD
Proceedings of the National Academy of Sciences of the United States of America110(34)E3179-88(2013 Aug)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases.
Mashimo T, Takizawa A, Voigt B, Yoshimi K, Hiai H, Kuramoto T, Serikawa T
PloS one5(1)e8870(2010 Jan)

E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene.
Jia J, Dai M, Zhuang Y
European journal of immunology38(10)2806-20(2008 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Il2rg gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Il2rg cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00232	NM_080889.1 Latest version!	Rattus norvegicus interleukin 2 receptor subunit gamma (Il2rg), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa62996	XM_017601899.1 Latest version!	Rattus norvegicus interleukin 2 receptor subunit gamma (Il2rg), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Il2rg ( NM_080889.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_543165.1 Rattus norvegicus interleukin 2 receptor subunit gamma (Il2rg), mRNA.

Price & Availability↑

CloneID	ORa00232
Clone ID Related Accession (Same CDS sequence)	NM_080889.1
Accession Version	NM_080889.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1107bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1555516800000
Organism	Rattus norvegicus(Norway rat)
Product	cytokine receptor common subunit gamma precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079343.1. On Apr 19, 2005 this sequence version replaced XM_343800.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079343.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGTTGAAAC CATTATTGCC ATCTAGATCC TTCTTACTCC TTCAGCTGCT TCTGCTGAGG 
GTAGGGTGGA GCTCCAAGGT CCTCATGTCC AGTGGGAATG AAGACACCAA ATCTGATCTC 
TTGCTGACTT CTATGGACCT TAAACATCTC AGTGTTCCTA CTCTGCCCCT CCCAGAGGTT 
CAATGCTTTG TGTTCAATGT CGAGTATATG AATTGCACTT GGAATAGCAG TTCTGAGCCT 
CAGCCGACCA ACCTCACTAT GCACTATAGG TACAAGGGAT CTGATAATAA TACATTCCAG 
GAGTGCAGCC ACTATCTGTT CTCAAAAGAG ATTACTTCTG GCTGTCAGAT ACAAAAAGAA 
GATATCCAGC TCTACCAGAC ATTTGTTGTC CAGCTTCAGG ACCCCCAGAA ACCCCAGAGG 
CGAGCCGAAC AGAAGCTAAA CCTACAGAAT CTTGTGATCC CATGGGCTCC AGAGAATCTA 
ACACTTTATA ACCTGAGTGA ATCTCAGGTA GAACTGAGGT GGAAAAGCAG ATACATAGAA 
CGCTGTTTAC AATACTTGGT GCAGTACCGG AGCAACCGAG ATCGAAGCTG GACGGAACAA 
ATAGTGGATC ATGAGCCTAG ATTCTCCCTG CCTAGTGTGG ATGAACAGAA GCTGTACACA 
TTTCGGGTTC GGAGCCGCTT TAACCCGATC TGTGGAAGTA CTCAACAGTG GAGTAAATGG 
AGCCAACCAA TCCACTGGGG GAGCCATACT GCAGAGGAGA ATCCTTCCTT GTTTGCACTG 
GAAGCTGTGC TTATCCCTGT TGGCACCATG GGGTTGATTA TTACCCTGAT CTTTGTGTAC 
TGTTGGTTGG AACGAATGCC TCGAATTCCC GCCATCAAGA ATCTAGAGGA TCTGGTTACT 
GAATACCATG GGAACTTTTC GGCCTGGAGT GGTGTGTCTA AAGGGCTGAC TGAGAGTCTG 
CAGCCAGACT ACAGTGAACG GTTCTGCCAC GTCAGTGAGA TTCCCCCGAA AGGAGGAGCC 
CTAGGAGAGG GGCCTGGAGG CTCTCCTTGC AGCCTTCATA GCCCTTACTG GCCTCCCCCA 
TGTTATTCTC TGAAGCCTGA AGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_543165.1
CDS	15..1121
Translation	MLKPLLPSRSFLLLQLLLLRVGWSSKVLMSSGNEDTKSDLLLTSMDLKHLSVPTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTMHYRYKGSDNNTFQECSHYLFSKEITSGCQIQKEDIQLYQTFVVQLQDPQKPQRRAEQKLNLQNLVIPWAPENLTLYNLSESQVELRWKSRYIERCLQYLVQYRSNRDRSWTEQIVDHEPRFSLPSVDEQKLYTFRVRSRFNPICGSTQQWSKWSQPIHWGSHTAEENPSLFALEAVLIPVGTMGLIITLIFVYCWLERMPRIPAIKNLEDLVTEYHGNFSAWSGVSKGLTESLQPDYSERFCHVSEIPPKGGALGEGPGGSPCSLHSPYWPPPCYSLKPEA

Target ORF information:

RefSeq Version	NM_080889.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 2 receptor subunit gamma (Il2rg), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080889.1

ORF Insert Sequence:

ATGTTGAAAC CATTATTGCC ATCTAGATCC TTCTTACTCC TTCAGCTGCT TCTGCTGAGG 
GTAGGGTGGA GCTCCAAGGT CCTCATGTCC AGTGGGAATG AAGACACCAA ATCTGATCTC 
TTGCTGACTT CTATGGACCT TAAACATCTC AGTGTTCCTA CTCTGCCCCT CCCAGAGGTT 
CAATGCTTTG TGTTCAATGT CGAGTATATG AATTGCACTT GGAATAGCAG TTCTGAGCCT 
CAGCCGACCA ACCTCACTAT GCACTATAGG TACAAGGGAT CTGATAATAA TACATTCCAG 
GAGTGCAGCC ACTATCTGTT CTCAAAAGAG ATTACTTCTG GCTGTCAGAT ACAAAAAGAA 
GATATCCAGC TCTACCAGAC ATTTGTTGTC CAGCTTCAGG ACCCCCAGAA ACCCCAGAGG 
CGAGCCGAAC AGAAGCTAAA CCTACAGAAT CTTGTGATCC CATGGGCTCC AGAGAATCTA 
ACACTTTATA ACCTGAGTGA ATCTCAGGTA GAACTGAGGT GGAAAAGCAG ATACATAGAA 
CGCTGTTTAC AATACTTGGT GCAGTACCGG AGCAACCGAG ATCGAAGCTG GACGGAACAA 
ATAGTGGATC ATGAGCCTAG ATTCTCCCTG CCTAGTGTGG ATGAACAGAA GCTGTACACA 
TTTCGGGTTC GGAGCCGCTT TAACCCGATC TGTGGAAGTA CTCAACAGTG GAGTAAATGG 
AGCCAACCAA TCCACTGGGG GAGCCATACT GCAGAGGAGA ATCCTTCCTT GTTTGCACTG 
GAAGCTGTGC TTATCCCTGT TGGCACCATG GGGTTGATTA TTACCCTGAT CTTTGTGTAC 
TGTTGGTTGG AACGAATGCC TCGAATTCCC GCCATCAAGA ATCTAGAGGA TCTGGTTACT 
GAATACCATG GGAACTTTTC GGCCTGGAGT GGTGTGTCTA AAGGGCTGAC TGAGAGTCTG 
CAGCCAGACT ACAGTGAACG GTTCTGCCAC GTCAGTGAGA TTCCCCCGAA AGGAGGAGCC 
CTAGGAGAGG GGCCTGGAGG CTCTCCTTGC AGCCTTCATA GCCCTTACTG GCCTCCCCCA 
TGTTATTCTC TGAAGCCTGA AGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il2rg ( XM_017601899.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457388.1 Rattus norvegicus interleukin 2 receptor subunit gamma (Il2rg), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa62996
Clone ID Related Accession (Same CDS sequence)	XM_017601899.1
Accession Version	XM_017601899.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	cytokine receptor common subunit gamma isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGAAAC CATTATTGCC ATCTAGATCC TTCTTACTCC TTCAGCTGCT TCTGCTGAGG 
GTAGGGTGGA GCTCCAAGGT CCTCATGTCC AGTGGGAATG AAGACACCAA ATCTGATCTC 
TTGCTGACTT CTATGGACCT TAAACATCTC AGTGTTCCTA CTCTGCCCCT CCCAGAGGTT 
CAATGCTTTG TGTTCAATGT CGAGTATATG AATTGCACTT GGAATAGCAG TTCTGAGCCT 
CAGCCGACCA ACCTCACTAT GCACTATAGG TACAAGGGAT CTGATAATAA TACATTCCAG 
GAGTGCAGCC ACTATCTGTT CTCAAAAGAG ATTACTTCTG GCTGTCAGAT ACAAAAAGAA 
GATATCCAGC TCTACCAGAC ATTTGTTGTC CAGCTTCAGG ACCCCCAGAA ACCCCAGAGG 
CGAGCCGAAC AGAAGCTAAA CCTACAGAAT CTTGTGATCC CATGGGCTCC AGAGAATCTA 
ACACTTTATA ACCTGAGTGA ATCTCAGGTA GAACTGAGGT GGAAAAGCAG ATACATAGAA 
CGCTGTTTAC AATACTTGGT GCAGTACCGG AGCAACCGAG ATCGAAGCTG GACGGAACAA 
ATAGTGGATC ATGAGCCTAG ATTCTCCCTG CCTAGTGTGG ATGAACAGAA GCTAGAATCC 
TTCCTTGTTT GCACTGGAAG CTGTGCTTAT CCCTGTTGGC ACCATGGGGT TGATTATTAC 
CCTGATCTTT GTGTACTGTT GGTTGGAACG AATGCCTCGA ATTCCCGCCA TCAAGAATCT 
AGAGGATCTG GTTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457388.1
CDS	55..852
Translation	MLKPLLPSRSFLLLQLLLLRVGWSSKVLMSSGNEDTKSDLLLTSMDLKHLSVPTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTMHYRYKGSDNNTFQECSHYLFSKEITSGCQIQKEDIQLYQTFVVQLQDPQKPQRRAEQKLNLQNLVIPWAPENLTLYNLSESQVELRWKSRYIERCLQYLVQYRSNRDRSWTEQIVDHEPRFSLPSVDEQKLESFLVCTGSCAYPCWHHGVDYYPDLCVLLVGTNASNSRHQESRGSGY

Target ORF information:

RefSeq Version	XM_017601899.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 2 receptor subunit gamma (Il2rg), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601899.1

ORF Insert Sequence:

ATGTTGAAAC CATTATTGCC ATCTAGATCC TTCTTACTCC TTCAGCTGCT TCTGCTGAGG 
GTAGGGTGGA GCTCCAAGGT CCTCATGTCC AGTGGGAATG AAGACACCAA ATCTGATCTC 
TTGCTGACTT CTATGGACCT TAAACATCTC AGTGTTCCTA CTCTGCCCCT CCCAGAGGTT 
CAATGCTTTG TGTTCAATGT CGAGTATATG AATTGCACTT GGAATAGCAG TTCTGAGCCT 
CAGCCGACCA ACCTCACTAT GCACTATAGG TACAAGGGAT CTGATAATAA TACATTCCAG 
GAGTGCAGCC ACTATCTGTT CTCAAAAGAG ATTACTTCTG GCTGTCAGAT ACAAAAAGAA 
GATATCCAGC TCTACCAGAC ATTTGTTGTC CAGCTTCAGG ACCCCCAGAA ACCCCAGAGG 
CGAGCCGAAC AGAAGCTAAA CCTACAGAAT CTTGTGATCC CATGGGCTCC AGAGAATCTA 
ACACTTTATA ACCTGAGTGA ATCTCAGGTA GAACTGAGGT GGAAAAGCAG ATACATAGAA 
CGCTGTTTAC AATACTTGGT GCAGTACCGG AGCAACCGAG ATCGAAGCTG GACGGAACAA 
ATAGTGGATC ATGAGCCTAG ATTCTCCCTG CCTAGTGTGG ATGAACAGAA GCTAGAATCC 
TTCCTTGTTT GCACTGGAAG CTGTGCTTAT CCCTGTTGGC ACCATGGGGT TGATTATTAC 
CCTGATCTTT GTGTACTGTT GGTTGGAACG AATGCCTCGA ATTCCCGCCA TCAAGAATCT 
AGAGGATCTG GTTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models.
Transplantation102(8)1271-1278(2018 08)
Ménoret S,Ouisse LH,Tesson L,Delbos F,Garnier D,Remy S,Usal C,Concordet JP,Giovannangeli C,Chenouard V,Brusselle L,Merieau E,Nerrière-Daguin V,Duteille F,Bellier-Waast F,Fraichard A,Nguyen TH,Anegon I

Conditionals by inversion provide a universal method for the generation of conditional alleles.
Proceedings of the National Academy of Sciences of the United States of America110(34)E3179-88(2013 Aug)
Economides AN,Frendewey D,Yang P,Dominguez MG,Dore AT,Lobov IB,Persaud T,Rojas J,McClain J,Lengyel P,Droguett G,Chernomorsky R,Stevens S,Auerbach W,Dechiara TM,Pouyemirou W,Cruz JM Jr,Feeley K,Mellis IA,Yasenchack J,Hatsell SJ,Xie L,Latres E,Huang L,Zhang Y,Pefanis E,Skokos D,Deckelbaum RA,Croll SD,Davis S,Valenzuela DM,Gale NW,Murphy AJ,Yancopoulos GD

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases.
PloS one5(1)e8870(2010 Jan)
Mashimo T,Takizawa A,Voigt B,Yoshimi K,Hiai H,Kuramoto T,Serikawa T

E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene.
European journal of immunology38(10)2806-20(2008 Oct)
Jia J,Dai M,Zhuang Y

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Il2rg cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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