Slc7a10 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc7a10
Entrez Gene ID	114518
Full Name	solute carrier family 7 member 10
Synonyms	Asc-1
General protein information	Preferred Names solute carrier family 7 member 10 Names asc-type amino acid transporter 1 D- and L-serine transporter Asc-1 D-serine transporter solute carrier family 7 (cationic amino acid transporter, y+ system), member 10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 solute carrier family 7, (neutral amino acid transporter, y+ system) member 10
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21
Summary	transports D- and L-serine with high affinity; may be essential for survival and dendrite growth of Purkinje neurons [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053726.2	NP_446178.2	asc-type amino acid transporter 1
XM_017588654.1	XP_017444143.1	asc-type amino acid transporter 1 isoform X2
XM_017588653.1	XP_017444142.1	asc-type amino acid transporter 1 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Slc7a10	NP_446178.2
Gallus gallus (chicken)	SLC7A10	XP_414136.2
Danio rerio (zebrafish)	slc7a10a	XP_695808.3
Canis lupus familiaris (dog)	SLC7A10	XP_541713.3
Xenopus tropicalis (tropical clawed frog)	slc7a10	XP_002935839.2
Homo sapiens (human)	SLC7A10	NP_062823.1
Danio rerio (zebrafish)	slc7a10b	XP_687825.2
Mus musculus (house mouse)	Slc7a10	NP_059090.3
Pan troglodytes (chimpanzee)	SLC7A10	XP_524204.2

Gene Ontology
Bibliography

Related articles in PubMed

Asc-1 transporter activation: an alternative to rescue age-related alterations in functional plasticity at rat hippocampal CA3/CA1 synapses.
Billard JM, Freret T
Journal of neurochemistry147(4)514-525(2018 11)

In vivo D-serine hetero-exchange through alanine-serine-cysteine (ASC) transporters detected by microelectrode biosensors.
Maucler C, Pernot P, Vasylieva N, Pollegioni L, Marinesco S
ACS chemical neuroscience4(5)772-81(2013 May)

Evidence from gene knockout studies implicates Asc-1 as the primary transporter mediating d-serine reuptake in the mouse CNS.
Rutter AR, Fradley RL, Garrett EM, Chapman KL, Lawrence JM, Rosahl TW, Patel S
The European journal of neuroscience25(6)1757-66(2007 Mar)

High affinity D- and L-serine transporter Asc-1: cloning and dendritic localization in the rat cerebral and cerebellar cortices.
Matsuo H, Kanai Y, Tokunaga M, Nakata T, Chairoungdua A, Ishimine H, Tsukada S, Ooigawa H, Nawashiro H, Kobayashi Y, Fukuda J, Endou H
Neuroscience letters358(2)123-6(2004 Mar)

Cloning and characterization of a human brain Na(+)-independent transporter for small neutral amino acids that transports D-serine with high affinity.
Nakauchi J, Matsuo H, Kim DK, Goto A, Chairoungdua A, Cha SH, Inatomi J, Shiokawa Y, Yamaguchi K, Saito I, Endou H, Kanai Y
Neuroscience letters287(3)231-5(2000 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Slc7a10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc7a10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa10437	NM_053726.2 Latest version!	Rattus norvegicus solute carrier family 7 member 10 (Slc7a10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa56292	XM_017588653.1 Latest version!	Rattus norvegicus solute carrier family 7 member 10 (Slc7a10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa56293	XM_017588654.1 Latest version!	Rattus norvegicus solute carrier family 7 member 10 (Slc7a10), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc7a10 ( NM_053726.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446178.2 Rattus norvegicus solute carrier family 7 member 10 (Slc7a10), mRNA.

Price & Availability↑

CloneID	ORa10437
Clone ID Related Accession (Same CDS sequence)	NM_053726.2
Accession Version	NM_053726.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577030400000
Organism	Rattus norvegicus(Norway rat)
Product	asc-type amino acid transporter 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB126813.1. On or before Aug 30, 2004 this sequence version replaced XM_346540.1, NM_053726.1. ##Evidence-Data-START## Transcript exon combination :: AB126813.1, BC127467.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGGCGGG ACAGCGACAT GACAGGCCAT ATACAGCAGC CAGGCGGGCG CGGGAACCCC 
AGCCCTGCGC CCTCGCCCTC CCCGGGCCCT GGTCCTGGCC CGGGCGCCTC GGAGCGGGTG 
GCACTCAAGA AAGAGATCGG GCTGGTGAGC GCCTGCACCA TCATCATCGG GAACATCATT 
GGCTCGGGTA TCTTCATCTC ACCGAAGGGC GTCCTGGAAC ACTCGGGCTC CGTGGGTTTG 
GCCCTCTTCG TCTGGGTCCT GGGTGGGGGC GTGACAGCTC TAGGCTCTCT CTGCTATGCA 
GAGCTGGGCG TCACCATCCC CAAGTCTGGT GGGGACTACG CCTATGTCAC TGAGATCTTC 
GGGGGCCTGG CTGGATTCCT GCTGCTCTGG AGTGCTGTCC TCATCATGTA CCCCACCAGC 
CTGGCTGTCA TCTCCATGAC ATTCTCCAAC TATGTGCTTC AGCCTGTCTT TCCCAACTGT 
ATCCCCCCAG CCACAGCCTC TCGAGTACTC TCCATGGCCT GCCTGATGCT CCTGACATGG 
GTGAACAGCT CCAGCGTACG CTGGGCCACG CGCATCCAGG TTATCTTCAC TGGCGGGAAG 
CTGTTGGCGT TGTCTCTCAT CATCACCGTG GGCTTTGTCC AGATCTTCCA AGGACACTTT 
GAAGAGCTGA GACCCACCAA TGCCTTCACC TTCTGGATGA CACCGTCTGT GGGTCACCTA 
GCCCTGGCTT TCCTCCAAGG TTCTTTTGCC TTCAGTGGTT GGAACTTCCT CAACTATGTC 
ACCGAGGAGC TGGTTGACCC TCGAAAGAAC CTACCTCGTG CCATCTTCAT TTCCATCCCA 
CTGGTCACCT TTGTGTACAC ATTCACCAAT GTTGCCTACT TCACTGCCAT GTCCCCCCAG 
GAGCTGCTGT CCTCCAACGC AGTGGCTGTG ACCTTCGGCG AGAAGCTGCT GGGCTACTTT 
TCGTGGGTCA TGCCTGTGTC TGTGGCGCTG TCTACTTTTG GAGGGATCAA TGGCTACCTG 
TTCACCTCAT CCAGGCTATG TTTCTCTGGA GCCCGAGAGG GACACTTACC CAGCTTTCTG 
GCCATGATTC ATGTCAGACG CTGTACCCCA ATCCCTGCCC TCCTTGTCTG TTGCGGGGCC 
ACAGCGGTCA TCATGCTCGT GGGTGACACA TACACACTCA TCAACTATGT GTCCTTCATC 
AACTACCTCT GCTACGGAGT CACTATCCTG GGCCTGCTTG TGCTGCGCTG GAGACGGCCG 
GCACTTCACA GGCCCATTAA GGTGAACCTC CTCATTCCTG TTGTGTACTT GGTGTTCTGG 
GCATTCCTCC TGGTCTTCAG CTTCATCTCG GAGCCCATGG TCTGTGGGGT CGGCATCATC 
ATTATCCTCA CTGGGGTCCC CATCTTCTTC CTGGGAGTGT TCTGGAGAAG CAAACCAAAG 
TGTGTACACA GATTCACAGA GTCCATGACA CGCTGGGGCC AGGAGCTGTG TTTCGTGGTT 
TACCCCCAGG GCTCCCTGGA GGAGGAGGAA AATGGCCCCA TGGGCCAGCC CTCCCCATTG 
CCCATCACGG ACAAGCCCTT GAAGACACAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446178.2
CDS	54..1646
Translation	MRRDSDMTGHIQQPGGRGNPSPAPSPSPGPGPGPGASERVALKKEIGLVSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVTIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPATASRVLSMACLMLLTWVNSSSVRWATRIQVIFTGGKLLALSLIITVGFVQIFQGHFEELRPTNAFTFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEELVDPRKNLPRAIFISIPLVTFVYTFTNVAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSFLAMIHVRRCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLVLRWRRPALHRPIKVNLLIPVVYLVFWAFLLVFSFISEPMVCGVGIIIILTGVPIFFLGVFWRSKPKCVHRFTESMTRWGQELCFVVYPQGSLEEEENGPMGQPSPLPITDKPLKTQ

Target ORF information:

RefSeq Version	NM_053726.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 7 member 10 (Slc7a10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053726.2

ORF Insert Sequence:

ATGAGGCGGG ACAGCGACAT GACAGGCCAT ATACAGCAGC CAGGCGGGCG CGGGAACCCC 
AGCCCTGCGC CCTCGCCCTC CCCGGGCCCT GGTCCTGGCC CGGGCGCCTC GGAGCGGGTG 
GCACTCAAGA AAGAGATCGG GCTGGTGAGC GCCTGCACCA TCATCATCGG GAACATCATT 
GGCTCGGGTA TCTTCATCTC ACCGAAGGGC GTCCTGGAAC ACTCGGGCTC CGTGGGTTTG 
GCCCTCTTCG TCTGGGTCCT GGGTGGGGGC GTGACAGCTC TAGGCTCTCT CTGCTATGCA 
GAGCTGGGCG TCACCATCCC CAAGTCTGGT GGGGACTACG CCTATGTCAC TGAGATCTTC 
GGGGGCCTGG CTGGATTCCT GCTGCTCTGG AGTGCTGTCC TCATCATGTA CCCCACCAGC 
CTGGCTGTCA TCTCCATGAC ATTCTCCAAC TATGTGCTTC AGCCTGTCTT TCCCAACTGT 
ATCCCCCCAG CCACAGCCTC TCGAGTACTC TCCATGGCCT GCCTGATGCT CCTGACATGG 
GTGAACAGCT CCAGCGTACG CTGGGCCACG CGCATCCAGG TTATCTTCAC TGGCGGGAAG 
CTGTTGGCGT TGTCTCTCAT CATCACCGTG GGCTTTGTCC AGATCTTCCA AGGACACTTT 
GAAGAGCTGA GACCCACCAA TGCCTTCACC TTCTGGATGA CACCGTCTGT GGGTCACCTA 
GCCCTGGCTT TCCTCCAAGG TTCTTTTGCC TTCAGTGGTT GGAACTTCCT CAACTATGTC 
ACCGAGGAGC TGGTTGACCC TCGAAAGAAC CTACCTCGTG CCATCTTCAT TTCCATCCCA 
CTGGTCACCT TTGTGTACAC ATTCACCAAT GTTGCCTACT TCACTGCCAT GTCCCCCCAG 
GAGCTGCTGT CCTCCAACGC AGTGGCTGTG ACCTTCGGCG AGAAGCTGCT GGGCTACTTT 
TCGTGGGTCA TGCCTGTGTC TGTGGCGCTG TCTACTTTTG GAGGGATCAA TGGCTACCTG 
TTCACCTCAT CCAGGCTATG TTTCTCTGGA GCCCGAGAGG GACACTTACC CAGCTTTCTG 
GCCATGATTC ATGTCAGACG CTGTACCCCA ATCCCTGCCC TCCTTGTCTG TTGCGGGGCC 
ACAGCGGTCA TCATGCTCGT GGGTGACACA TACACACTCA TCAACTATGT GTCCTTCATC 
AACTACCTCT GCTACGGAGT CACTATCCTG GGCCTGCTTG TGCTGCGCTG GAGACGGCCG 
GCACTTCACA GGCCCATTAA GGTGAACCTC CTCATTCCTG TTGTGTACTT GGTGTTCTGG 
GCATTCCTCC TGGTCTTCAG CTTCATCTCG GAGCCCATGG TCTGTGGGGT CGGCATCATC 
ATTATCCTCA CTGGGGTCCC CATCTTCTTC CTGGGAGTGT TCTGGAGAAG CAAACCAAAG 
TGTGTACACA GATTCACAGA GTCCATGACA CGCTGGGGCC AGGAGCTGTG TTTCGTGGTT 
TACCCCCAGG GCTCCCTGGA GGAGGAGGAA AATGGCCCCA TGGGCCAGCC CTCCCCATTG 
CCCATCACGG ACAAGCCCTT GAAGACACAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc7a10 ( XM_017588653.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444142.1 Rattus norvegicus solute carrier family 7 member 10 (Slc7a10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa56292
Clone ID Related Accession (Same CDS sequence)	XM_017588653.1
Accession Version	XM_017588653.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1869bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	asc-type amino acid transporter 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGCGGG ACAGCGACAT GACAGGCCAT ATACAGCAGC CAGGCGGGCG CGGGAACCCC 
AGCCCTGCGC CCTCGCCCTC CCCGGGCCCT GGTCCTGGCC CGGGCGCCTC GGAGCGGGTG 
GCACTCAAGA AAGAGATCGG GCTGGTGAGC GCCTGCACCA TCATCATCGG GAACATCATT 
GGCTCGGGTA TCTTCATCTC ACCGAAGGGC GTCCTGGAAC ACTCGGGCTC CGTGGGTTTG 
GCCCTCTTCG TCTGGGTCCT GGGTGGGGGC GTGACAGCTC TAGGCTCTCT CTGCTATGCA 
GAGCTGGGCG TCACCATCCC CAAGTCTGGT GGGGACTACG CCTATGTCAC TGAGATCTTC 
GGGGGCCTGG CTGGATTCCT GCTGCTCTGG AGTGCTGTCC TCATCATGTA CCCCACCAGC 
CTGGCTGTCA TCTCCATGAC ATTCTCCAAC TATGTGCTTC AGCCTGTCTT TCCCAACTGT 
ATCCCCCCAG CCACAGCCTC TCGAGTACTC TCCATGGCCT GCCTGATGCT CCTGACATGG 
GTGAACAGCT CCAGCGTACG CTGGGCCACG CGCATCCAGG TTATCTTCAC TGGCGGGAAG 
CTGTTGGCGT TGTCTCTCAT CATCACCGTG GGCTTTGTCC AGATCTTCCA AGGACACTTT 
GAAGAGCTGA GACCCACCAA TGCCTTCACC TTCTGGATGA CACCGTCTGT GGGTCACCTA 
GCCCTGGCTT TCCTCCAAGG TTCTTTTGCC TTCAGTGGTT GGAACTTCCT CAACTATGTC 
ACCGAGGAGC TGGTTGACCC TCGAAAGAAC CTACCTCGTG CCATCTTCAT TTCCATCCCA 
CTGGTCACCT TTGTGTACAC ATTCACCAAT GTTGCCTACT TCACTGCCAT GTCCCCCCAG 
GAGCTGCTGT CCTCCAACGC AGTGGCTGTG ACCTTCGGCG AGAAGCTGCT GGGCTACTTT 
TCGTGGGTCA TGCCTGTGTC TGTGGCGCTG TCTACTTTTG GAGGGATCAA TGGCTACCTG 
TTCACCTCAT CCAGGCTATG TTTCTCTGGA GCCCGAGAGG GACACTTACC CAGCTTTCTG 
GCCATGATTC ATGTCAGACG CTGTACCCCA ATCCCTGCCC TCCTTGTCTG TTGCGGGGCC 
ACAGCGGTCA TCATGCTCGT GGGTGACACA TACACACTCA TCAACTATGT GTCCTTCATC 
AACTACCTCT GCTACGGAGT CACTATCCTG GGCCTGCTTG TGCTGCGCTG GAGACGGCCG 
GCACTTCACA GGCCCATTAA GGTGAACCTC CTCATTCCTG TTGTGTACTT GGTGTTCTGG 
GCATTCCTCC TGGTCTTCAG CTTCATCTCG GAGCCCATGG TCTGTGGGGT CGGCATCATC 
ATTATCCTCA CTGGGGTCCC CATCTTCTTC CTGGGAGTGT TCTGGAGAAG CAAACCAAAG 
TGTGTACACA GATTCACAGG TGAGAAGGTT CTTGCCTCTT GTAGGCAGAG GTGGGTATCT 
CTTATGATCC TACCCCAGTG CAGGGGACCT TCCATCAGCC TGGCTGGTGA CACAGGACCC 
GGTCACTTCC CTCAAACTTC CTCTACATAT AGATATGGCT GGGATCCATC TGCAAAGGAA 
ACAACTCCCT GCCTAAGGGA GGTGTCCAGA GTTAGGGTCA TCCCTGTCTT AAAGGATCAA 
AAACCCACCC ACTCCCGCCA TGGTCTGTCT GTCTGTCTTG TCTGTCTATT CTTAGAGTCC 
ATGACACGCT GGGGCCAGGA GCTGTGTTTC GTGGTTTACC CCCAGGGCTC CCTGGAGGAG 
GAGGAAAATG GCCCCATGGG CCAGCCCTCC CCATTGCCCA TCACGGACAA GCCCTTGAAG 
ACACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444142.1
CDS	132..2000
Translation	MRRDSDMTGHIQQPGGRGNPSPAPSPSPGPGPGPGASERVALKKEIGLVSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVTIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPATASRVLSMACLMLLTWVNSSSVRWATRIQVIFTGGKLLALSLIITVGFVQIFQGHFEELRPTNAFTFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEELVDPRKNLPRAIFISIPLVTFVYTFTNVAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSFLAMIHVRRCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLVLRWRRPALHRPIKVNLLIPVVYLVFWAFLLVFSFISEPMVCGVGIIIILTGVPIFFLGVFWRSKPKCVHRFTGEKVLASCRQRWVSLMILPQCRGPSISLAGDTGPGHFPQTSSTYRYGWDPSAKETTPCLREVSRVRVIPVLKDQKPTHSRHGLSVCLVCLFLESMTRWGQELCFVVYPQGSLEEEENGPMGQPSPLPITDKPLKTQ

Target ORF information:

RefSeq Version	XM_017588653.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 7 member 10 (Slc7a10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017588653.1

ORF Insert Sequence:

ATGAGGCGGG ACAGCGACAT GACAGGCCAT ATACAGCAGC CAGGCGGGCG CGGGAACCCC 
AGCCCTGCGC CCTCGCCCTC CCCGGGCCCT GGTCCTGGCC CGGGCGCCTC GGAGCGGGTG 
GCACTCAAGA AAGAGATCGG GCTGGTGAGC GCCTGCACCA TCATCATCGG GAACATCATT 
GGCTCGGGTA TCTTCATCTC ACCGAAGGGC GTCCTGGAAC ACTCGGGCTC CGTGGGTTTG 
GCCCTCTTCG TCTGGGTCCT GGGTGGGGGC GTGACAGCTC TAGGCTCTCT CTGCTATGCA 
GAGCTGGGCG TCACCATCCC CAAGTCTGGT GGGGACTACG CCTATGTCAC TGAGATCTTC 
GGGGGCCTGG CTGGATTCCT GCTGCTCTGG AGTGCTGTCC TCATCATGTA CCCCACCAGC 
CTGGCTGTCA TCTCCATGAC ATTCTCCAAC TATGTGCTTC AGCCTGTCTT TCCCAACTGT 
ATCCCCCCAG CCACAGCCTC TCGAGTACTC TCCATGGCCT GCCTGATGCT CCTGACATGG 
GTGAACAGCT CCAGCGTACG CTGGGCCACG CGCATCCAGG TTATCTTCAC TGGCGGGAAG 
CTGTTGGCGT TGTCTCTCAT CATCACCGTG GGCTTTGTCC AGATCTTCCA AGGACACTTT 
GAAGAGCTGA GACCCACCAA TGCCTTCACC TTCTGGATGA CACCGTCTGT GGGTCACCTA 
GCCCTGGCTT TCCTCCAAGG TTCTTTTGCC TTCAGTGGTT GGAACTTCCT CAACTATGTC 
ACCGAGGAGC TGGTTGACCC TCGAAAGAAC CTACCTCGTG CCATCTTCAT TTCCATCCCA 
CTGGTCACCT TTGTGTACAC ATTCACCAAT GTTGCCTACT TCACTGCCAT GTCCCCCCAG 
GAGCTGCTGT CCTCCAACGC AGTGGCTGTG ACCTTCGGCG AGAAGCTGCT GGGCTACTTT 
TCGTGGGTCA TGCCTGTGTC TGTGGCGCTG TCTACTTTTG GAGGGATCAA TGGCTACCTG 
TTCACCTCAT CCAGGCTATG TTTCTCTGGA GCCCGAGAGG GACACTTACC CAGCTTTCTG 
GCCATGATTC ATGTCAGACG CTGTACCCCA ATCCCTGCCC TCCTTGTCTG TTGCGGGGCC 
ACAGCGGTCA TCATGCTCGT GGGTGACACA TACACACTCA TCAACTATGT GTCCTTCATC 
AACTACCTCT GCTACGGAGT CACTATCCTG GGCCTGCTTG TGCTGCGCTG GAGACGGCCG 
GCACTTCACA GGCCCATTAA GGTGAACCTC CTCATTCCTG TTGTGTACTT GGTGTTCTGG 
GCATTCCTCC TGGTCTTCAG CTTCATCTCG GAGCCCATGG TCTGTGGGGT CGGCATCATC 
ATTATCCTCA CTGGGGTCCC CATCTTCTTC CTGGGAGTGT TCTGGAGAAG CAAACCAAAG 
TGTGTACACA GATTCACAGG TGAGAAGGTT CTTGCCTCTT GTAGGCAGAG GTGGGTATCT 
CTTATGATCC TACCCCAGTG CAGGGGACCT TCCATCAGCC TGGCTGGTGA CACAGGACCC 
GGTCACTTCC CTCAAACTTC CTCTACATAT AGATATGGCT GGGATCCATC TGCAAAGGAA 
ACAACTCCCT GCCTAAGGGA GGTGTCCAGA GTTAGGGTCA TCCCTGTCTT AAAGGATCAA 
AAACCCACCC ACTCCCGCCA TGGTCTGTCT GTCTGTCTTG TCTGTCTATT CTTAGAGTCC 
ATGACACGCT GGGGCCAGGA GCTGTGTTTC GTGGTTTACC CCCAGGGCTC CCTGGAGGAG 
GAGGAAAATG GCCCCATGGG CCAGCCCTCC CCATTGCCCA TCACGGACAA GCCCTTGAAG 
ACACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc7a10 ( XM_017588654.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444143.1 Rattus norvegicus solute carrier family 7 member 10 (Slc7a10), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa56293
Clone ID Related Accession (Same CDS sequence)	XM_017588654.1
Accession Version	XM_017588654.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	asc-type amino acid transporter 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGCGGG ACAGCGACAT GACAGGCCAT ATACAGCAGC CAGGCGGGCG CGGGAACCCC 
AGCCCTGCGC CCTCGCCCTC CCCGGGCCCT GGTCCTGGCC CGGGCGCCTC GGAGCGGGTG 
GCACTCAAGA AAGAGATCGG GCTGGTGAGC GCCTGCACCA TCATCATCGG GAACATCATT 
GGCTCGGGTA TCTTCATCTC ACCGAAGGGC GTCCTGGAAC ACTCGGGCTC CGTGGGTTTG 
GCCCTCTTCG TCTGGGTCCT GGGTGGGGGC GTGACAGCTC TAGGCTCTCT CTGCTATGCA 
GAGCTGGGCG TCACCATCCC CAAGTCTGGT GGGGACTACG CCTATGTCAC TGAGATCTTC 
GGGGGCCTGG CTGGATTCCT GCTGCTCTGG AGTGCTGTCC TCATCATGTA CCCCACCAGC 
CTGGCTGTCA TCTCCATGAC ATTCTCCAAC TATGTGCTTC AGCCTGTCTT TCCCAACTGT 
ATCCCCCCAG CCACAGCCTC TCGAGTACTC TCCATGGCCT GCCTGATGCT CCTGACATGG 
GTGAACAGCT CCAGCGTACG CTGGGCCACG CGCATCCAGG TTATCTTCAC TGGCGGGAAG 
CTGTTGGCGT TGTCTCTCAT CATCACCGTG GGCTTTGTCC AGATCTTCCA AGGACACTTT 
GAAGAGCTGA GACCCACCAA TGCCTTCACC TTCTGGATGA CACCGTCTGT GGGTCACCTA 
GCCCTGGCTT TCCTCCAAGG TTCTTTTGCC TTCAGTGGTT GGAACTTCCT CAACTATGTC 
ACCGAGGAGC TGGTTGACCC TCGAAAGAAC CTACCTCGTG CCATCTTCAT TTCCATCCCA 
CTGGTCACCT TTGTGTACAC ATTCACCAAT GTTGCCTACT TCACTGCCAT GTCCCCCCAG 
GAGCTGCTGT CCTCCAACGC AGTGGCTGTG ACCTTCGGCG AGAAGCTGCT GGGCTACTTT 
TCGTGGGTCA TGCCTGTGTC TGTGGCGCTG TCTACTTTTG GAGGGATCAA TGGCTACCTG 
TTCACCTCAT CCAGGCTATG TTTCTCTGGA GCCCGAGAGG GACACTTACC CAGCTTTCTG 
GCCATGATTC ATGTCAGACG CTGTACCCCA ATCCCTGCCC TCCTTGTCTG TGTGAACCTC 
CTCATTCCTG TTGTGTACTT GGTGTTCTGG GCATTCCTCC TGGTCTTCAG CTTCATCTCG 
GAGCCCATGG TCTGTGGGGT CGGCATCATC ATTATCCTCA CTGGGGTCCC CATCTTCTTC 
CTGGGAGTGT TCTGGAGAAG CAAACCAAAG TGTGTACACA GATTCACAGG TGAGAAGGTT 
CTTGCCTCTT GTAGGCAGAG GTGGGTATCT CTTATGATCC TACCCCAGTG CAGGGGACCT 
TCCATCAGCC TGGCTGGTGA CACAGGACCC GGTCACTTCC CTCAAACTTC CTCTACATAT 
AGATATGGCT GGGATCCATC TGCAAAGGAA ACAACTCCCT GCCTAAGGGA GGTGTCCAGA 
GTTAGGGTCA TCCCTGTCTT AAAGGATCAA AAACCCACCC ACTCCCGCCA TGGTCTGTCT 
GTCTGTCTTG TCTGTCTATT CTTAGAGTCC ATGACACGCT GGGGCCAGGA GCTGTGTTTC 
GTGGTTTACC CCCAGGGCTC CCTGGAGGAG GAGGAAAATG GCCCCATGGG CCAGCCCTCC 
CCATTGCCCA TCACGGACAA GCCCTTGAAG ACACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444143.1
CDS	132..1850
Translation	MRRDSDMTGHIQQPGGRGNPSPAPSPSPGPGPGPGASERVALKKEIGLVSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVTIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPATASRVLSMACLMLLTWVNSSSVRWATRIQVIFTGGKLLALSLIITVGFVQIFQGHFEELRPTNAFTFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEELVDPRKNLPRAIFISIPLVTFVYTFTNVAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSFLAMIHVRRCTPIPALLVCVNLLIPVVYLVFWAFLLVFSFISEPMVCGVGIIIILTGVPIFFLGVFWRSKPKCVHRFTGEKVLASCRQRWVSLMILPQCRGPSISLAGDTGPGHFPQTSSTYRYGWDPSAKETTPCLREVSRVRVIPVLKDQKPTHSRHGLSVCLVCLFLESMTRWGQELCFVVYPQGSLEEEENGPMGQPSPLPITDKPLKTQ

Target ORF information:

RefSeq Version	XM_017588654.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 7 member 10 (Slc7a10), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017588654.1

ORF Insert Sequence:

ATGAGGCGGG ACAGCGACAT GACAGGCCAT ATACAGCAGC CAGGCGGGCG CGGGAACCCC 
AGCCCTGCGC CCTCGCCCTC CCCGGGCCCT GGTCCTGGCC CGGGCGCCTC GGAGCGGGTG 
GCACTCAAGA AAGAGATCGG GCTGGTGAGC GCCTGCACCA TCATCATCGG GAACATCATT 
GGCTCGGGTA TCTTCATCTC ACCGAAGGGC GTCCTGGAAC ACTCGGGCTC CGTGGGTTTG 
GCCCTCTTCG TCTGGGTCCT GGGTGGGGGC GTGACAGCTC TAGGCTCTCT CTGCTATGCA 
GAGCTGGGCG TCACCATCCC CAAGTCTGGT GGGGACTACG CCTATGTCAC TGAGATCTTC 
GGGGGCCTGG CTGGATTCCT GCTGCTCTGG AGTGCTGTCC TCATCATGTA CCCCACCAGC 
CTGGCTGTCA TCTCCATGAC ATTCTCCAAC TATGTGCTTC AGCCTGTCTT TCCCAACTGT 
ATCCCCCCAG CCACAGCCTC TCGAGTACTC TCCATGGCCT GCCTGATGCT CCTGACATGG 
GTGAACAGCT CCAGCGTACG CTGGGCCACG CGCATCCAGG TTATCTTCAC TGGCGGGAAG 
CTGTTGGCGT TGTCTCTCAT CATCACCGTG GGCTTTGTCC AGATCTTCCA AGGACACTTT 
GAAGAGCTGA GACCCACCAA TGCCTTCACC TTCTGGATGA CACCGTCTGT GGGTCACCTA 
GCCCTGGCTT TCCTCCAAGG TTCTTTTGCC TTCAGTGGTT GGAACTTCCT CAACTATGTC 
ACCGAGGAGC TGGTTGACCC TCGAAAGAAC CTACCTCGTG CCATCTTCAT TTCCATCCCA 
CTGGTCACCT TTGTGTACAC ATTCACCAAT GTTGCCTACT TCACTGCCAT GTCCCCCCAG 
GAGCTGCTGT CCTCCAACGC AGTGGCTGTG ACCTTCGGCG AGAAGCTGCT GGGCTACTTT 
TCGTGGGTCA TGCCTGTGTC TGTGGCGCTG TCTACTTTTG GAGGGATCAA TGGCTACCTG 
TTCACCTCAT CCAGGCTATG TTTCTCTGGA GCCCGAGAGG GACACTTACC CAGCTTTCTG 
GCCATGATTC ATGTCAGACG CTGTACCCCA ATCCCTGCCC TCCTTGTCTG TGTGAACCTC 
CTCATTCCTG TTGTGTACTT GGTGTTCTGG GCATTCCTCC TGGTCTTCAG CTTCATCTCG 
GAGCCCATGG TCTGTGGGGT CGGCATCATC ATTATCCTCA CTGGGGTCCC CATCTTCTTC 
CTGGGAGTGT TCTGGAGAAG CAAACCAAAG TGTGTACACA GATTCACAGG TGAGAAGGTT 
CTTGCCTCTT GTAGGCAGAG GTGGGTATCT CTTATGATCC TACCCCAGTG CAGGGGACCT 
TCCATCAGCC TGGCTGGTGA CACAGGACCC GGTCACTTCC CTCAAACTTC CTCTACATAT 
AGATATGGCT GGGATCCATC TGCAAAGGAA ACAACTCCCT GCCTAAGGGA GGTGTCCAGA 
GTTAGGGTCA TCCCTGTCTT AAAGGATCAA AAACCCACCC ACTCCCGCCA TGGTCTGTCT 
GTCTGTCTTG TCTGTCTATT CTTAGAGTCC ATGACACGCT GGGGCCAGGA GCTGTGTTTC 
GTGGTTTACC CCCAGGGCTC CCTGGAGGAG GAGGAAAATG GCCCCATGGG CCAGCCCTCC 
CCATTGCCCA TCACGGACAA GCCCTTGAAG ACACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Asc-1 transporter activation: an alternative to rescue age-related alterations in functional plasticity at rat hippocampal CA3/CA1 synapses.
Journal of neurochemistry147(4)514-525(2018 11)
Billard JM,Freret T

In vivo D-serine hetero-exchange through alanine-serine-cysteine (ASC) transporters detected by microelectrode biosensors.
ACS chemical neuroscience4(5)772-81(2013 May)
Maucler C,Pernot P,Vasylieva N,Pollegioni L,Marinesco S

Evidence from gene knockout studies implicates Asc-1 as the primary transporter mediating d-serine reuptake in the mouse CNS.
The European journal of neuroscience25(6)1757-66(2007 Mar)
Rutter AR,Fradley RL,Garrett EM,Chapman KL,Lawrence JM,Rosahl TW,Patel S

High affinity D- and L-serine transporter Asc-1: cloning and dendritic localization in the rat cerebral and cerebellar cortices.
Neuroscience letters358(2)123-6(2004 Mar)
Matsuo H,Kanai Y,Tokunaga M,Nakata T,Chairoungdua A,Ishimine H,Tsukada S,Ooigawa H,Nawashiro H,Kobayashi Y,Fukuda J,Endou H

Cloning and characterization of a human brain Na(+)-independent transporter for small neutral amino acids that transports D-serine with high affinity.
Neuroscience letters287(3)231-5(2000 Jun)
Nakauchi J,Matsuo H,Kim DK,Goto A,Chairoungdua A,Cha SH,Inatomi J,Shiokawa Y,Yamaguchi K,Saito I,Endou H,Kanai Y

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Slc7a10 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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