KDF1 cDNA ORF clone, Pan troglodytes(chimpanzee)

Gene
Clones
gRNAs

Summary

Gene Symbol	KDF1
Entrez Gene ID	737621
Full Name	keratinocyte differentiation factor 1
Synonyms	C1H1orf172
General protein information	Preferred Names keratinocyte differentiation factor 1 Names keratinocyte differentiation factor 1
Gene Type	protein-coding
Organism	Pan troglodytes(chimpanzee)

mRNA and Protein(s)

mRNA	Protein	Name
XM_016957041.1	XP_016812530.1	keratinocyte differentiation factor 1
XM_016957044.1	XP_016812533.1	keratinocyte differentiation factor 1
XM_001146912.4	XP_001146912.1	keratinocyte differentiation factor 1
XM_001146912.5	XP_001146912.1	keratinocyte differentiation factor 1
XM_016957041.2	XP_016812530.1	keratinocyte differentiation factor 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	C2H1orf172	NP_001092573.1
Mus musculus (house mouse)	1810019J16Rik	NP_598468.2
Danio rerio (zebrafish)	si:ch73-112l20.2	XP_001338378.3
Rattus norvegicus (Norway rat)	LOC100911383	XP_003750103.1
Macaca mulatta (Rhesus monkey)	LOC715312	XP_001110637.1
Homo sapiens (human)	C1orf172	NP_689578.2
Gallus gallus (chicken)	C23H1ORF172	XP_001232503.2
Canis lupus familiaris (dog)	C2H1orf172	XP_854940.1
Pan troglodytes (chimpanzee)	C1H1orf172	XP_001146912.1
Rattus norvegicus (Norway rat)	RGD1303271	NP_001004268.1
Xenopus tropicalis (tropical clawed frog)	c1orf172	NP_001072939.1

Gene Ontology

The following KDF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KDF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OPc59050	XM_016957044.1 Latest version!	Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OPc59050	XM_016957041.2 Latest version!	Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OPc59050	XM_001146912.5 Latest version!	Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OPc59050	XM_001146912.4	Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OPc59050	XM_016957041.1	Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KDF1 ( XM_016957041.1 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_016812530.1 Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OPc59050
Clone ID Related Accession (Same CDS sequence)	XM_016957041.1 , XM_016957044.1 , XM_001146912.4 , XM_001146912.5 , XM_016957041.2
Accession Version	XM_016957041.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1464710400000
Organism	Pan troglodytes(chimpanzee)
Product	keratinocyte differentiation factor 1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006468.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Pan troglodytes Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCGCC CTGGACACCC CCGCCCAGCA TCTGGGCCTC CACGCTTGGG ACCCTGGGAG 
CGGCCAACAG AGCTATGTCT GGAGACATAT GATAAACCAC CTCAGCCCCC ACCAAGCCGC 
CGCACCCGTA GACCAGACCC CAAGGACCCT GGCCACCATG GGCCAGAGAG CATTACCTTC 
ATCTCTGGCT CTGCTGAGCC GGCCCCTGAG TCCCCCACCT GCTGCCTGCT CTGGCGACCC 
TGGGTGTGGG AGTGGTGCCG GGCTGCCTTC TGCTTCCGCC GCTGCCGGGA TTGCCTCCAG 
CGCTGTGGAG CCTGTGTGCG GGGATGCAGC CCCTGCCTGT CTACTGAGGA CTCCACTGAG 
GGGACTGCCG AAGCCAACTG GGCCAAGGAG CACAATGGAG TGCCCCCCAG CCCTGATCGT 
GCACCCCCCA GCCGGCGGGA TGGCCAGCGG CTCAAGTCAA CCATGGGCAG CAGCTTCAGC 
TACCCCGATG TTAAGCTCAA AGGCATCCCT GTGTATCCCT ACCCGAGGGC CACCTCCCCA 
GCCCCTGATG CGGACTCCTG CTGCAAGGAG CCACTGGCCG ATCCCCCACC CATGCGACAC 
AGCCTGCCCA GCACCCTTGC CAGTAGTCCT CGTGGCTCTG AGGAGTACTA TTCTTTCCAT 
GAGTCGGACC TGGACCTGCC GGAGATGGGC AGTGGCTCCA TGTCGAGCCG AGAAATTGAT 
GTGCTCATCT TCAAGAAGCT GACAGAGCTG TTCAGCGTAC ACCAGATCGA TGAGCTGGCC 
AAGTGCACAT CAGACACTGT GTTCCTGGAG AAGACCAGTA AGATCTCGGA CCTTATCAGC 
AGCATCACGC AGGACTACCA CCTGGATGAG CAGGATGCTG AGGGCCGCCT GGTACGCGGC 
ATCATTCGCA TTAGTACCCG AAAGAGCCGT GCTCGCCCAC AGACCTCGGA GGGTCGTTCA 
ACTCGGGCTG CTGCCCCAAC CGCTGCTGCC CCTGACAGTG GCCATGAGAC CATGGTGGGC 
TCAGGTCTCA GCCAGGATGA GCTGACAGTG CAGATCTCCC AGGAGACGAC TGCAGATGCC 
ATCGCCCGGA AGCTGAGGCC TTATGGAGTT CCAGGGTACC CAGCAAGCCA TGACTCATCC 
TTCCAGGGCA CCGACACAGA CTCGTCGGGG GCACCCTTGC TCCAGGTGTA CTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016812530.1
CDS	124..1320
Translation	MPRPGHPRPASGPPRLGPWERPTELCLETYDKPPQPPPSRRTRRPDPKDPGHHGPESITFISGSAEPAPESPTCCLLWRPWVWEWCRAAFCFRRCRDCLQRCGACVRGCSPCLSTEDSTEGTAEANWAKEHNGVPPSPDRAPPSRRDGQRLKSTMGSSFSYPDVKLKGIPVYPYPRATSPAPDADSCCKEPLADPPPMRHSLPSTLASSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRARPQTSEGRSTRAAAPTAAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGVPGYPASHDSSFQGTDTDSSGAPLLQVYC

Target ORF information:

RefSeq Version	XM_016957041.1
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_016957041.1

ORF Insert Sequence:

ATGCCCCGCC CTGGACACCC CCGCCCAGCA TCTGGGCCTC CACGCTTGGG ACCCTGGGAG 
CGGCCAACAG AGCTATGTCT GGAGACATAT GATAAACCAC CTCAGCCCCC ACCAAGCCGC 
CGCACCCGTA GACCAGACCC CAAGGACCCT GGCCACCATG GGCCAGAGAG CATTACCTTC 
ATCTCTGGCT CTGCTGAGCC GGCCCCTGAG TCCCCCACCT GCTGCCTGCT CTGGCGACCC 
TGGGTGTGGG AGTGGTGCCG GGCTGCCTTC TGCTTCCGCC GCTGCCGGGA TTGCCTCCAG 
CGCTGTGGAG CCTGTGTGCG GGGATGCAGC CCCTGCCTGT CTACTGAGGA CTCCACTGAG 
GGGACTGCCG AAGCCAACTG GGCCAAGGAG CACAATGGAG TGCCCCCCAG CCCTGATCGT 
GCACCCCCCA GCCGGCGGGA TGGCCAGCGG CTCAAGTCAA CCATGGGCAG CAGCTTCAGC 
TACCCCGATG TTAAGCTCAA AGGCATCCCT GTGTATCCCT ACCCGAGGGC CACCTCCCCA 
GCCCCTGATG CGGACTCCTG CTGCAAGGAG CCACTGGCCG ATCCCCCACC CATGCGACAC 
AGCCTGCCCA GCACCCTTGC CAGTAGTCCT CGTGGCTCTG AGGAGTACTA TTCTTTCCAT 
GAGTCGGACC TGGACCTGCC GGAGATGGGC AGTGGCTCCA TGTCGAGCCG AGAAATTGAT 
GTGCTCATCT TCAAGAAGCT GACAGAGCTG TTCAGCGTAC ACCAGATCGA TGAGCTGGCC 
AAGTGCACAT CAGACACTGT GTTCCTGGAG AAGACCAGTA AGATCTCGGA CCTTATCAGC 
AGCATCACGC AGGACTACCA CCTGGATGAG CAGGATGCTG AGGGCCGCCT GGTACGCGGC 
ATCATTCGCA TTAGTACCCG AAAGAGCCGT GCTCGCCCAC AGACCTCGGA GGGTCGTTCA 
ACTCGGGCTG CTGCCCCAAC CGCTGCTGCC CCTGACAGTG GCCATGAGAC CATGGTGGGC 
TCAGGTCTCA GCCAGGATGA GCTGACAGTG CAGATCTCCC AGGAGACGAC TGCAGATGCC 
ATCGCCCGGA AGCTGAGGCC TTATGGAGTT CCAGGGTACC CAGCAAGCCA TGACTCATCC 
TTCCAGGGCA CCGACACAGA CTCGTCGGGG GCACCCTTGC TCCAGGTGTA CTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KDF1 ( XM_016957044.1 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_016812533.1 Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OPc59050
Clone ID Related Accession (Same CDS sequence)	XM_016957041.1 , XM_016957044.1 , XM_001146912.4 , XM_001146912.5 , XM_016957041.2
Accession Version	XM_016957044.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1521388800000
Organism	Pan troglodytes(chimpanzee)
Product	keratinocyte differentiation factor 1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_036879.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Pan troglodytes Annotation Release 105 Annotation Version :: 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCGCC CTGGACACCC CCGCCCAGCA TCTGGGCCTC CACGCTTGGG ACCCTGGGAG 
CGGCCAACAG AGCTATGTCT GGAGACATAT GATAAACCAC CTCAGCCCCC ACCAAGCCGC 
CGCACCCGTA GACCAGACCC CAAGGACCCT GGCCACCATG GGCCAGAGAG CATTACCTTC 
ATCTCTGGCT CTGCTGAGCC GGCCCCTGAG TCCCCCACCT GCTGCCTGCT CTGGCGACCC 
TGGGTGTGGG AGTGGTGCCG GGCTGCCTTC TGCTTCCGCC GCTGCCGGGA TTGCCTCCAG 
CGCTGTGGAG CCTGTGTGCG GGGATGCAGC CCCTGCCTGT CTACTGAGGA CTCCACTGAG 
GGGACTGCCG AAGCCAACTG GGCCAAGGAG CACAATGGAG TGCCCCCCAG CCCTGATCGT 
GCACCCCCCA GCCGGCGGGA TGGCCAGCGG CTCAAGTCAA CCATGGGCAG CAGCTTCAGC 
TACCCCGATG TTAAGCTCAA AGGCATCCCT GTGTATCCCT ACCCGAGGGC CACCTCCCCA 
GCCCCTGATG CGGACTCCTG CTGCAAGGAG CCACTGGCCG ATCCCCCACC CATGCGACAC 
AGCCTGCCCA GCACCCTTGC CAGTAGTCCT CGTGGCTCTG AGGAGTACTA TTCTTTCCAT 
GAGTCGGACC TGGACCTGCC GGAGATGGGC AGTGGCTCCA TGTCGAGCCG AGAAATTGAT 
GTGCTCATCT TCAAGAAGCT GACAGAGCTG TTCAGCGTAC ACCAGATCGA TGAGCTGGCC 
AAGTGCACAT CAGACACTGT GTTCCTGGAG AAGACCAGTA AGATCTCGGA CCTTATCAGC 
AGCATCACGC AGGACTACCA CCTGGATGAG CAGGATGCTG AGGGCCGCCT GGTACGCGGC 
ATCATTCGCA TTAGTACCCG AAAGAGCCGT GCTCGCCCAC AGACCTCGGA GGGTCGTTCA 
ACTCGGGCTG CTGCCCCAAC CGCTGCTGCC CCTGACAGTG GCCATGAGAC CATGGTGGGC 
TCAGGTCTCA GCCAGGATGA GCTGACAGTG CAGATCTCCC AGGAGACGAC TGCAGATGCC 
ATCGCCCGGA AGCTGAGGCC TTATGGAGTT CCAGGGTACC CAGCAAGCCA TGACTCATCC 
TTCCAGGGCA CCGACACAGA CTCGTCGGGG GCACCCTTGC TCCAGGTGTA CTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016812533.1
CDS	135..1331
Translation	MPRPGHPRPASGPPRLGPWERPTELCLETYDKPPQPPPSRRTRRPDPKDPGHHGPESITFISGSAEPAPESPTCCLLWRPWVWEWCRAAFCFRRCRDCLQRCGACVRGCSPCLSTEDSTEGTAEANWAKEHNGVPPSPDRAPPSRRDGQRLKSTMGSSFSYPDVKLKGIPVYPYPRATSPAPDADSCCKEPLADPPPMRHSLPSTLASSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRARPQTSEGRSTRAAAPTAAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGVPGYPASHDSSFQGTDTDSSGAPLLQVYC

Target ORF information:

RefSeq Version	XM_016957044.1
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_016957044.1

ORF Insert Sequence:

ATGCCCCGCC CTGGACACCC CCGCCCAGCA TCTGGGCCTC CACGCTTGGG ACCCTGGGAG 
CGGCCAACAG AGCTATGTCT GGAGACATAT GATAAACCAC CTCAGCCCCC ACCAAGCCGC 
CGCACCCGTA GACCAGACCC CAAGGACCCT GGCCACCATG GGCCAGAGAG CATTACCTTC 
ATCTCTGGCT CTGCTGAGCC GGCCCCTGAG TCCCCCACCT GCTGCCTGCT CTGGCGACCC 
TGGGTGTGGG AGTGGTGCCG GGCTGCCTTC TGCTTCCGCC GCTGCCGGGA TTGCCTCCAG 
CGCTGTGGAG CCTGTGTGCG GGGATGCAGC CCCTGCCTGT CTACTGAGGA CTCCACTGAG 
GGGACTGCCG AAGCCAACTG GGCCAAGGAG CACAATGGAG TGCCCCCCAG CCCTGATCGT 
GCACCCCCCA GCCGGCGGGA TGGCCAGCGG CTCAAGTCAA CCATGGGCAG CAGCTTCAGC 
TACCCCGATG TTAAGCTCAA AGGCATCCCT GTGTATCCCT ACCCGAGGGC CACCTCCCCA 
GCCCCTGATG CGGACTCCTG CTGCAAGGAG CCACTGGCCG ATCCCCCACC CATGCGACAC 
AGCCTGCCCA GCACCCTTGC CAGTAGTCCT CGTGGCTCTG AGGAGTACTA TTCTTTCCAT 
GAGTCGGACC TGGACCTGCC GGAGATGGGC AGTGGCTCCA TGTCGAGCCG AGAAATTGAT 
GTGCTCATCT TCAAGAAGCT GACAGAGCTG TTCAGCGTAC ACCAGATCGA TGAGCTGGCC 
AAGTGCACAT CAGACACTGT GTTCCTGGAG AAGACCAGTA AGATCTCGGA CCTTATCAGC 
AGCATCACGC AGGACTACCA CCTGGATGAG CAGGATGCTG AGGGCCGCCT GGTACGCGGC 
ATCATTCGCA TTAGTACCCG AAAGAGCCGT GCTCGCCCAC AGACCTCGGA GGGTCGTTCA 
ACTCGGGCTG CTGCCCCAAC CGCTGCTGCC CCTGACAGTG GCCATGAGAC CATGGTGGGC 
TCAGGTCTCA GCCAGGATGA GCTGACAGTG CAGATCTCCC AGGAGACGAC TGCAGATGCC 
ATCGCCCGGA AGCTGAGGCC TTATGGAGTT CCAGGGTACC CAGCAAGCCA TGACTCATCC 
TTCCAGGGCA CCGACACAGA CTCGTCGGGG GCACCCTTGC TCCAGGTGTA CTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KDF1 ( XM_001146912.4 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_001146912.1 Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OPc59050
Clone ID Related Accession (Same CDS sequence)	XM_016957041.1 , XM_016957044.1 , XM_001146912.4 , XM_001146912.5 , XM_016957041.2
Accession Version	XM_001146912.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1464710400000
Organism	Pan troglodytes(chimpanzee)
Product	keratinocyte differentiation factor 1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006468.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 2, 2016 this sequence version replaced XM_001146912.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Pan troglodytes Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCGCC CTGGACACCC CCGCCCAGCA TCTGGGCCTC CACGCTTGGG ACCCTGGGAG 
CGGCCAACAG AGCTATGTCT GGAGACATAT GATAAACCAC CTCAGCCCCC ACCAAGCCGC 
CGCACCCGTA GACCAGACCC CAAGGACCCT GGCCACCATG GGCCAGAGAG CATTACCTTC 
ATCTCTGGCT CTGCTGAGCC GGCCCCTGAG TCCCCCACCT GCTGCCTGCT CTGGCGACCC 
TGGGTGTGGG AGTGGTGCCG GGCTGCCTTC TGCTTCCGCC GCTGCCGGGA TTGCCTCCAG 
CGCTGTGGAG CCTGTGTGCG GGGATGCAGC CCCTGCCTGT CTACTGAGGA CTCCACTGAG 
GGGACTGCCG AAGCCAACTG GGCCAAGGAG CACAATGGAG TGCCCCCCAG CCCTGATCGT 
GCACCCCCCA GCCGGCGGGA TGGCCAGCGG CTCAAGTCAA CCATGGGCAG CAGCTTCAGC 
TACCCCGATG TTAAGCTCAA AGGCATCCCT GTGTATCCCT ACCCGAGGGC CACCTCCCCA 
GCCCCTGATG CGGACTCCTG CTGCAAGGAG CCACTGGCCG ATCCCCCACC CATGCGACAC 
AGCCTGCCCA GCACCCTTGC CAGTAGTCCT CGTGGCTCTG AGGAGTACTA TTCTTTCCAT 
GAGTCGGACC TGGACCTGCC GGAGATGGGC AGTGGCTCCA TGTCGAGCCG AGAAATTGAT 
GTGCTCATCT TCAAGAAGCT GACAGAGCTG TTCAGCGTAC ACCAGATCGA TGAGCTGGCC 
AAGTGCACAT CAGACACTGT GTTCCTGGAG AAGACCAGTA AGATCTCGGA CCTTATCAGC 
AGCATCACGC AGGACTACCA CCTGGATGAG CAGGATGCTG AGGGCCGCCT GGTACGCGGC 
ATCATTCGCA TTAGTACCCG AAAGAGCCGT GCTCGCCCAC AGACCTCGGA GGGTCGTTCA 
ACTCGGGCTG CTGCCCCAAC CGCTGCTGCC CCTGACAGTG GCCATGAGAC CATGGTGGGC 
TCAGGTCTCA GCCAGGATGA GCTGACAGTG CAGATCTCCC AGGAGACGAC TGCAGATGCC 
ATCGCCCGGA AGCTGAGGCC TTATGGAGTT CCAGGGTACC CAGCAAGCCA TGACTCATCC 
TTCCAGGGCA CCGACACAGA CTCGTCGGGG GCACCCTTGC TCCAGGTGTA CTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_001146912.1
CDS	135..1331
Translation	MPRPGHPRPASGPPRLGPWERPTELCLETYDKPPQPPPSRRTRRPDPKDPGHHGPESITFISGSAEPAPESPTCCLLWRPWVWEWCRAAFCFRRCRDCLQRCGACVRGCSPCLSTEDSTEGTAEANWAKEHNGVPPSPDRAPPSRRDGQRLKSTMGSSFSYPDVKLKGIPVYPYPRATSPAPDADSCCKEPLADPPPMRHSLPSTLASSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRARPQTSEGRSTRAAAPTAAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGVPGYPASHDSSFQGTDTDSSGAPLLQVYC

Target ORF information:

RefSeq Version	XM_001146912.4
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_001146912.4

ORF Insert Sequence:

ATGCCCCGCC CTGGACACCC CCGCCCAGCA TCTGGGCCTC CACGCTTGGG ACCCTGGGAG 
CGGCCAACAG AGCTATGTCT GGAGACATAT GATAAACCAC CTCAGCCCCC ACCAAGCCGC 
CGCACCCGTA GACCAGACCC CAAGGACCCT GGCCACCATG GGCCAGAGAG CATTACCTTC 
ATCTCTGGCT CTGCTGAGCC GGCCCCTGAG TCCCCCACCT GCTGCCTGCT CTGGCGACCC 
TGGGTGTGGG AGTGGTGCCG GGCTGCCTTC TGCTTCCGCC GCTGCCGGGA TTGCCTCCAG 
CGCTGTGGAG CCTGTGTGCG GGGATGCAGC CCCTGCCTGT CTACTGAGGA CTCCACTGAG 
GGGACTGCCG AAGCCAACTG GGCCAAGGAG CACAATGGAG TGCCCCCCAG CCCTGATCGT 
GCACCCCCCA GCCGGCGGGA TGGCCAGCGG CTCAAGTCAA CCATGGGCAG CAGCTTCAGC 
TACCCCGATG TTAAGCTCAA AGGCATCCCT GTGTATCCCT ACCCGAGGGC CACCTCCCCA 
GCCCCTGATG CGGACTCCTG CTGCAAGGAG CCACTGGCCG ATCCCCCACC CATGCGACAC 
AGCCTGCCCA GCACCCTTGC CAGTAGTCCT CGTGGCTCTG AGGAGTACTA TTCTTTCCAT 
GAGTCGGACC TGGACCTGCC GGAGATGGGC AGTGGCTCCA TGTCGAGCCG AGAAATTGAT 
GTGCTCATCT TCAAGAAGCT GACAGAGCTG TTCAGCGTAC ACCAGATCGA TGAGCTGGCC 
AAGTGCACAT CAGACACTGT GTTCCTGGAG AAGACCAGTA AGATCTCGGA CCTTATCAGC 
AGCATCACGC AGGACTACCA CCTGGATGAG CAGGATGCTG AGGGCCGCCT GGTACGCGGC 
ATCATTCGCA TTAGTACCCG AAAGAGCCGT GCTCGCCCAC AGACCTCGGA GGGTCGTTCA 
ACTCGGGCTG CTGCCCCAAC CGCTGCTGCC CCTGACAGTG GCCATGAGAC CATGGTGGGC 
TCAGGTCTCA GCCAGGATGA GCTGACAGTG CAGATCTCCC AGGAGACGAC TGCAGATGCC 
ATCGCCCGGA AGCTGAGGCC TTATGGAGTT CCAGGGTACC CAGCAAGCCA TGACTCATCC 
TTCCAGGGCA CCGACACAGA CTCGTCGGGG GCACCCTTGC TCCAGGTGTA CTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KDF1 ( XM_001146912.5 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_001146912.1 Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OPc59050
Clone ID Related Accession (Same CDS sequence)	XM_016957041.1 , XM_016957044.1 , XM_001146912.4 , XM_001146912.5 , XM_016957041.2
Accession Version	XM_001146912.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1521388800000
Organism	Pan troglodytes(chimpanzee)
Product	keratinocyte differentiation factor 1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_036879.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 20, 2018 this sequence version replaced XM_001146912.4. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Pan troglodytes Annotation Release 105 Annotation Version :: 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCGCC CTGGACACCC CCGCCCAGCA TCTGGGCCTC CACGCTTGGG ACCCTGGGAG 
CGGCCAACAG AGCTATGTCT GGAGACATAT GATAAACCAC CTCAGCCCCC ACCAAGCCGC 
CGCACCCGTA GACCAGACCC CAAGGACCCT GGCCACCATG GGCCAGAGAG CATTACCTTC 
ATCTCTGGCT CTGCTGAGCC GGCCCCTGAG TCCCCCACCT GCTGCCTGCT CTGGCGACCC 
TGGGTGTGGG AGTGGTGCCG GGCTGCCTTC TGCTTCCGCC GCTGCCGGGA TTGCCTCCAG 
CGCTGTGGAG CCTGTGTGCG GGGATGCAGC CCCTGCCTGT CTACTGAGGA CTCCACTGAG 
GGGACTGCCG AAGCCAACTG GGCCAAGGAG CACAATGGAG TGCCCCCCAG CCCTGATCGT 
GCACCCCCCA GCCGGCGGGA TGGCCAGCGG CTCAAGTCAA CCATGGGCAG CAGCTTCAGC 
TACCCCGATG TTAAGCTCAA AGGCATCCCT GTGTATCCCT ACCCGAGGGC CACCTCCCCA 
GCCCCTGATG CGGACTCCTG CTGCAAGGAG CCACTGGCCG ATCCCCCACC CATGCGACAC 
AGCCTGCCCA GCACCCTTGC CAGTAGTCCT CGTGGCTCTG AGGAGTACTA TTCTTTCCAT 
GAGTCGGACC TGGACCTGCC GGAGATGGGC AGTGGCTCCA TGTCGAGCCG AGAAATTGAT 
GTGCTCATCT TCAAGAAGCT GACAGAGCTG TTCAGCGTAC ACCAGATCGA TGAGCTGGCC 
AAGTGCACAT CAGACACTGT GTTCCTGGAG AAGACCAGTA AGATCTCGGA CCTTATCAGC 
AGCATCACGC AGGACTACCA CCTGGATGAG CAGGATGCTG AGGGCCGCCT GGTACGCGGC 
ATCATTCGCA TTAGTACCCG AAAGAGCCGT GCTCGCCCAC AGACCTCGGA GGGTCGTTCA 
ACTCGGGCTG CTGCCCCAAC CGCTGCTGCC CCTGACAGTG GCCATGAGAC CATGGTGGGC 
TCAGGTCTCA GCCAGGATGA GCTGACAGTG CAGATCTCCC AGGAGACGAC TGCAGATGCC 
ATCGCCCGGA AGCTGAGGCC TTATGGAGTT CCAGGGTACC CAGCAAGCCA TGACTCATCC 
TTCCAGGGCA CCGACACAGA CTCGTCGGGG GCACCCTTGC TCCAGGTGTA CTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_001146912.1
CDS	134..1330
Translation	MPRPGHPRPASGPPRLGPWERPTELCLETYDKPPQPPPSRRTRRPDPKDPGHHGPESITFISGSAEPAPESPTCCLLWRPWVWEWCRAAFCFRRCRDCLQRCGACVRGCSPCLSTEDSTEGTAEANWAKEHNGVPPSPDRAPPSRRDGQRLKSTMGSSFSYPDVKLKGIPVYPYPRATSPAPDADSCCKEPLADPPPMRHSLPSTLASSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRARPQTSEGRSTRAAAPTAAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGVPGYPASHDSSFQGTDTDSSGAPLLQVYC

Target ORF information:

RefSeq Version	XM_001146912.5
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_001146912.5

ORF Insert Sequence:

ATGCCCCGCC CTGGACACCC CCGCCCAGCA TCTGGGCCTC CACGCTTGGG ACCCTGGGAG 
CGGCCAACAG AGCTATGTCT GGAGACATAT GATAAACCAC CTCAGCCCCC ACCAAGCCGC 
CGCACCCGTA GACCAGACCC CAAGGACCCT GGCCACCATG GGCCAGAGAG CATTACCTTC 
ATCTCTGGCT CTGCTGAGCC GGCCCCTGAG TCCCCCACCT GCTGCCTGCT CTGGCGACCC 
TGGGTGTGGG AGTGGTGCCG GGCTGCCTTC TGCTTCCGCC GCTGCCGGGA TTGCCTCCAG 
CGCTGTGGAG CCTGTGTGCG GGGATGCAGC CCCTGCCTGT CTACTGAGGA CTCCACTGAG 
GGGACTGCCG AAGCCAACTG GGCCAAGGAG CACAATGGAG TGCCCCCCAG CCCTGATCGT 
GCACCCCCCA GCCGGCGGGA TGGCCAGCGG CTCAAGTCAA CCATGGGCAG CAGCTTCAGC 
TACCCCGATG TTAAGCTCAA AGGCATCCCT GTGTATCCCT ACCCGAGGGC CACCTCCCCA 
GCCCCTGATG CGGACTCCTG CTGCAAGGAG CCACTGGCCG ATCCCCCACC CATGCGACAC 
AGCCTGCCCA GCACCCTTGC CAGTAGTCCT CGTGGCTCTG AGGAGTACTA TTCTTTCCAT 
GAGTCGGACC TGGACCTGCC GGAGATGGGC AGTGGCTCCA TGTCGAGCCG AGAAATTGAT 
GTGCTCATCT TCAAGAAGCT GACAGAGCTG TTCAGCGTAC ACCAGATCGA TGAGCTGGCC 
AAGTGCACAT CAGACACTGT GTTCCTGGAG AAGACCAGTA AGATCTCGGA CCTTATCAGC 
AGCATCACGC AGGACTACCA CCTGGATGAG CAGGATGCTG AGGGCCGCCT GGTACGCGGC 
ATCATTCGCA TTAGTACCCG AAAGAGCCGT GCTCGCCCAC AGACCTCGGA GGGTCGTTCA 
ACTCGGGCTG CTGCCCCAAC CGCTGCTGCC CCTGACAGTG GCCATGAGAC CATGGTGGGC 
TCAGGTCTCA GCCAGGATGA GCTGACAGTG CAGATCTCCC AGGAGACGAC TGCAGATGCC 
ATCGCCCGGA AGCTGAGGCC TTATGGAGTT CCAGGGTACC CAGCAAGCCA TGACTCATCC 
TTCCAGGGCA CCGACACAGA CTCGTCGGGG GCACCCTTGC TCCAGGTGTA CTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KDF1 ( XM_016957041.2 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_016812530.1 Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X2, mRNA.

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CloneID	OPc59050
Clone ID Related Accession (Same CDS sequence)	XM_016957041.1 , XM_016957044.1 , XM_001146912.4 , XM_001146912.5 , XM_016957041.2
Accession Version	XM_016957041.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1521388800000
Organism	Pan troglodytes(chimpanzee)
Product	keratinocyte differentiation factor 1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_036879.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 20, 2018 this sequence version replaced XM_016957041.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Pan troglodytes Annotation Release 105 Annotation Version :: 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCGCC CTGGACACCC CCGCCCAGCA TCTGGGCCTC CACGCTTGGG ACCCTGGGAG 
CGGCCAACAG AGCTATGTCT GGAGACATAT GATAAACCAC CTCAGCCCCC ACCAAGCCGC 
CGCACCCGTA GACCAGACCC CAAGGACCCT GGCCACCATG GGCCAGAGAG CATTACCTTC 
ATCTCTGGCT CTGCTGAGCC GGCCCCTGAG TCCCCCACCT GCTGCCTGCT CTGGCGACCC 
TGGGTGTGGG AGTGGTGCCG GGCTGCCTTC TGCTTCCGCC GCTGCCGGGA TTGCCTCCAG 
CGCTGTGGAG CCTGTGTGCG GGGATGCAGC CCCTGCCTGT CTACTGAGGA CTCCACTGAG 
GGGACTGCCG AAGCCAACTG GGCCAAGGAG CACAATGGAG TGCCCCCCAG CCCTGATCGT 
GCACCCCCCA GCCGGCGGGA TGGCCAGCGG CTCAAGTCAA CCATGGGCAG CAGCTTCAGC 
TACCCCGATG TTAAGCTCAA AGGCATCCCT GTGTATCCCT ACCCGAGGGC CACCTCCCCA 
GCCCCTGATG CGGACTCCTG CTGCAAGGAG CCACTGGCCG ATCCCCCACC CATGCGACAC 
AGCCTGCCCA GCACCCTTGC CAGTAGTCCT CGTGGCTCTG AGGAGTACTA TTCTTTCCAT 
GAGTCGGACC TGGACCTGCC GGAGATGGGC AGTGGCTCCA TGTCGAGCCG AGAAATTGAT 
GTGCTCATCT TCAAGAAGCT GACAGAGCTG TTCAGCGTAC ACCAGATCGA TGAGCTGGCC 
AAGTGCACAT CAGACACTGT GTTCCTGGAG AAGACCAGTA AGATCTCGGA CCTTATCAGC 
AGCATCACGC AGGACTACCA CCTGGATGAG CAGGATGCTG AGGGCCGCCT GGTACGCGGC 
ATCATTCGCA TTAGTACCCG AAAGAGCCGT GCTCGCCCAC AGACCTCGGA GGGTCGTTCA 
ACTCGGGCTG CTGCCCCAAC CGCTGCTGCC CCTGACAGTG GCCATGAGAC CATGGTGGGC 
TCAGGTCTCA GCCAGGATGA GCTGACAGTG CAGATCTCCC AGGAGACGAC TGCAGATGCC 
ATCGCCCGGA AGCTGAGGCC TTATGGAGTT CCAGGGTACC CAGCAAGCCA TGACTCATCC 
TTCCAGGGCA CCGACACAGA CTCGTCGGGG GCACCCTTGC TCCAGGTGTA CTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016812530.1
CDS	122..1318
Translation	MPRPGHPRPASGPPRLGPWERPTELCLETYDKPPQPPPSRRTRRPDPKDPGHHGPESITFISGSAEPAPESPTCCLLWRPWVWEWCRAAFCFRRCRDCLQRCGACVRGCSPCLSTEDSTEGTAEANWAKEHNGVPPSPDRAPPSRRDGQRLKSTMGSSFSYPDVKLKGIPVYPYPRATSPAPDADSCCKEPLADPPPMRHSLPSTLASSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRARPQTSEGRSTRAAAPTAAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGVPGYPASHDSSFQGTDTDSSGAPLLQVYC

Target ORF information:

RefSeq Version	XM_016957041.2
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes keratinocyte differentiation factor 1 (KDF1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_016957041.2

ORF Insert Sequence:

ATGCCCCGCC CTGGACACCC CCGCCCAGCA TCTGGGCCTC CACGCTTGGG ACCCTGGGAG 
CGGCCAACAG AGCTATGTCT GGAGACATAT GATAAACCAC CTCAGCCCCC ACCAAGCCGC 
CGCACCCGTA GACCAGACCC CAAGGACCCT GGCCACCATG GGCCAGAGAG CATTACCTTC 
ATCTCTGGCT CTGCTGAGCC GGCCCCTGAG TCCCCCACCT GCTGCCTGCT CTGGCGACCC 
TGGGTGTGGG AGTGGTGCCG GGCTGCCTTC TGCTTCCGCC GCTGCCGGGA TTGCCTCCAG 
CGCTGTGGAG CCTGTGTGCG GGGATGCAGC CCCTGCCTGT CTACTGAGGA CTCCACTGAG 
GGGACTGCCG AAGCCAACTG GGCCAAGGAG CACAATGGAG TGCCCCCCAG CCCTGATCGT 
GCACCCCCCA GCCGGCGGGA TGGCCAGCGG CTCAAGTCAA CCATGGGCAG CAGCTTCAGC 
TACCCCGATG TTAAGCTCAA AGGCATCCCT GTGTATCCCT ACCCGAGGGC CACCTCCCCA 
GCCCCTGATG CGGACTCCTG CTGCAAGGAG CCACTGGCCG ATCCCCCACC CATGCGACAC 
AGCCTGCCCA GCACCCTTGC CAGTAGTCCT CGTGGCTCTG AGGAGTACTA TTCTTTCCAT 
GAGTCGGACC TGGACCTGCC GGAGATGGGC AGTGGCTCCA TGTCGAGCCG AGAAATTGAT 
GTGCTCATCT TCAAGAAGCT GACAGAGCTG TTCAGCGTAC ACCAGATCGA TGAGCTGGCC 
AAGTGCACAT CAGACACTGT GTTCCTGGAG AAGACCAGTA AGATCTCGGA CCTTATCAGC 
AGCATCACGC AGGACTACCA CCTGGATGAG CAGGATGCTG AGGGCCGCCT GGTACGCGGC 
ATCATTCGCA TTAGTACCCG AAAGAGCCGT GCTCGCCCAC AGACCTCGGA GGGTCGTTCA 
ACTCGGGCTG CTGCCCCAAC CGCTGCTGCC CCTGACAGTG GCCATGAGAC CATGGTGGGC 
TCAGGTCTCA GCCAGGATGA GCTGACAGTG CAGATCTCCC AGGAGACGAC TGCAGATGCC 
ATCGCCCGGA AGCTGAGGCC TTATGGAGTT CCAGGGTACC CAGCAAGCCA TGACTCATCC 
TTCCAGGGCA CCGACACAGA CTCGTCGGGG GCACCCTTGC TCCAGGTGTA CTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

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KDF1 cDNA ORF clone, Pan troglodytes(chimpanzee)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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