KCNMB1 cDNA ORF clone, Oryctolagus cuniculus(rabbit)

Gene
Clones
gRNAs

Summary

Gene Symbol	KCNMB1
Entrez Gene ID	100009034
Full Name	potassium calcium-activated channel subfamily M regulatory beta subunit 1
Synonyms	BKBETA
Gene Type	protein-coding
Organism	Oryctolagus cuniculus(rabbit)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001082225.1	NP_001075694.1	calcium-activated potassium channel subunit beta-1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Molecular cloning, tissue distribution and bioinformatics analyses of the rabbit BK channel beta1 subunit gene.
Zhang XY, Wang S, Yan Z, Wan Y, Wang W, Cui GB, Du P, Ma KJ, Han W, Zhang YQ, Wei JG
Molecular biology reports35(4)649-55(2008 Dec)

BK-{beta}1 subunit: immunolocalization in the mammalian connecting tubule and its role in the kaliuretic response to volume expansion.
Pluznick JL, Wei P, Grimm PR, Sansom SC
American journal of physiology. Renal physiology288(4)F846-54(2005 Apr)

Comparative study of the molecular and functional expression of L-type Ca2+ channels and large-conductance, Ca2+-activated K+ channels in rabbit aorta and vas deferens smooth muscle.
Ohya S, Yamamura H, Muraki K, Watanabe M, Imaizumi Y
Pflugers Archiv : European journal of physiology441(5)611-20(2001 Feb)

Interaction of charybdotoxin S10A with single maxi-K channels: kinetics of blockade depend on the presence of the beta 1 subunit.
Giangiacomo KM, Fremont V, Mullmann TJ, Hanner M, Cox RH, Garcia ML
Biochemistry39(20)6115-22(2000 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KCNMB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNMB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OOb00011	NM_001082225.1 Latest version!	Oryctolagus cuniculus potassium calcium-activated channel subfamily M regulatory beta subunit 1 (KCNMB1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KCNMB1 ( NM_001082225.1 ) cDNA ORF clone, Oryctolagus cuniculus(rabbit) -> NP_001075694.1 Oryctolagus cuniculus potassium calcium-activated channel subfamily M regulatory beta subunit 1 (KCNMB1), mRNA.

Price & Availability↑

CloneID	OOb00011
Clone ID Related Accession (Same CDS sequence)	NM_001082225.1
Accession Version	NM_001082225.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Oryctolagus cuniculus(rabbit)
Product	calcium-activated potassium channel subunit beta-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ821756.2. ##Evidence-Data-START## Transcript exon combination :: DQ821756.2, AB009313.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03328699, SAMN03328700 [ECO:0000350] ##Evidence-Data-END##

ATGGGGAAGA AGTTGGTGAT GGCCCAGAAG CGAGGAGAGA CTAGAGCCCT TTGCCTGGGT 
GTGGCCATGG TGATGTGTGC TGTCATCACC TACTACATCC TGGGAACGAC TATGCTGCCC 
CTCTACCAGA AAAGCGTGTG GACCCAGGAA TCCTTGTGTC GGCTGATTGA GACCAACATC 
AGGGACCAGG AGGAGCTGGA GGGCAAGAAG GTGCCGCAGT ACCCATGCCT GTGGGTCAAT 
GTGTCAGCCG TGGGCAAGTG GGCTGTGCTG TACCACACGG AGGAGACTCG GGACCGGAAT 
CAGCAGTGCT CCTACATCCC AGGCAGCCTG GACAACTACC AGATGGCCCT GGCCGACGTG 
GAGAAGGTCA GAGCCAAATT CCACGAGCGC CAGGTTTTCT ACTGCTTCTC CACGACGCAG 
GAGAACGAGA CCAGCGTCCT GTATCAGCGT CTGTACGGGC CCCAGGCCCT CCTCGCCTCC 
CTCTTCTGGC CCACCTTCCT GCTCACCGGT GGCCTCCTCA TTATTGCCAT GGTGAAGATC 
AACCGGTCCC TCTCCATCCT GGCGGCCCAG AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001075694.1
CDS	448..1023
Translation	MGKKLVMAQKRGETRALCLGVAMVMCAVITYYILGTTMLPLYQKSVWTQESLCRLIETNIRDQEELEGKKVPQYPCLWVNVSAVGKWAVLYHTEETRDRNQQCSYIPGSLDNYQMALADVEKVRAKFHERQVFYCFSTTQENETSVLYQRLYGPQALLASLFWPTFLLTGGLLIIAMVKINRSLSILAAQK

Target ORF information:

RefSeq Version	NM_001082225.1
Organism	Oryctolagus cuniculus(rabbit)
Definition	Oryctolagus cuniculus potassium calcium-activated channel subfamily M regulatory beta subunit 1 (KCNMB1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001082225.1

ORF Insert Sequence:

ATGGGGAAGA AGTTGGTGAT GGCCCAGAAG CGAGGAGAGA CTAGAGCCCT TTGCCTGGGT 
GTGGCCATGG TGATGTGTGC TGTCATCACC TACTACATCC TGGGAACGAC TATGCTGCCC 
CTCTACCAGA AAAGCGTGTG GACCCAGGAA TCCTTGTGTC GGCTGATTGA GACCAACATC 
AGGGACCAGG AGGAGCTGGA GGGCAAGAAG GTGCCGCAGT ACCCATGCCT GTGGGTCAAT 
GTGTCAGCCG TGGGCAAGTG GGCTGTGCTG TACCACACGG AGGAGACTCG GGACCGGAAT 
CAGCAGTGCT CCTACATCCC AGGCAGCCTG GACAACTACC AGATGGCCCT GGCCGACGTG 
GAGAAGGTCA GAGCCAAATT CCACGAGCGC CAGGTTTTCT ACTGCTTCTC CACGACGCAG 
GAGAACGAGA CCAGCGTCCT GTATCAGCGT CTGTACGGGC CCCAGGCCCT CCTCGCCTCC 
CTCTTCTGGC CCACCTTCCT GCTCACCGGT GGCCTCCTCA TTATTGCCAT GGTGAAGATC 
AACCGGTCCC TCTCCATCCT GGCGGCCCAG AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Molecular cloning, tissue distribution and bioinformatics analyses of the rabbit BK channel beta1 subunit gene.
Molecular biology reports35(4)649-55(2008 Dec)
Zhang XY,Wang S,Yan Z,Wan Y,Wang W,Cui GB,Du P,Ma KJ,Han W,Zhang YQ,Wei JG

BK-{beta}1 subunit: immunolocalization in the mammalian connecting tubule and its role in the kaliuretic response to volume expansion.
American journal of physiology. Renal physiology288(4)F846-54(2005 Apr)
Pluznick JL,Wei P,Grimm PR,Sansom SC

Comparative study of the molecular and functional expression of L-type Ca2+ channels and large-conductance, Ca2+-activated K+ channels in rabbit aorta and vas deferens smooth muscle.
Pflugers Archiv : European journal of physiology441(5)611-20(2001 Feb)
Ohya S,Yamamura H,Muraki K,Watanabe M,Imaizumi Y

Interaction of charybdotoxin S10A with single maxi-K channels: kinetics of blockade depend on the presence of the beta 1 subunit.
Biochemistry39(20)6115-22(2000 May)
Giangiacomo KM,Fremont V,Mullmann TJ,Hanner M,Cox RH,Garcia ML