Sirt3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sirt3
Entrez Gene ID	64384
Full Name	sirtuin 3
Synonyms	2310003L23Rik,AI848213,Sir2l3
General protein information	Preferred Names sirtuin 3 Names NAD-dependent protein deacetylase sirtuin-3 NAD-dependent deacetylase sirtuin-3 SIR2-like protein 3 SIRT3L mitochondrial mSIR2L3 mitochondrial protein lysine deacetylase regulatory protein SIR2 homolog 3 silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 F4-F5

mRNA and Protein(s)

mRNA	Protein	Name
XM_006536223.3	XP_006536286.1	NAD-dependent protein deacetylase sirtuin-3 isoform X2
XM_006536222.3	XP_006536285.1	NAD-dependent protein deacetylase sirtuin-3 isoform X1
NM_001177804.1	NP_001171275.1	NAD-dependent protein deacetylase sirtuin-3 isoform 3
NM_001127351.1	NP_001120823.1	NAD-dependent protein deacetylase sirtuin-3 isoform 1
XM_006536223.4	XP_006536286.1	NAD-dependent protein deacetylase sirtuin-3 isoform X2
XM_006536222.4	XP_006536285.1	NAD-dependent protein deacetylase sirtuin-3 isoform X1
NM_022433.2	NP_071878.2	NAD-dependent protein deacetylase sirtuin-3 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SIRT3	XP_003312891.1
Mus musculus (house mouse)	Sirt3	NP_001171275.1
Xenopus tropicalis (tropical clawed frog)	sirt3	XP_002937698.2
Danio rerio (zebrafish)	sirt3	NP_001073643.1
Bos taurus (cattle)	SIRT3	NP_001193598.1
Gallus gallus (chicken)	SIRT3	NP_001186422.1
Homo sapiens (human)	SIRT3	NP_036371.1
Macaca mulatta (Rhesus monkey)	SIRT3	XP_001116486.2
Canis lupus familiaris (dog)	SIRT3	XP_855809.1
Rattus norvegicus (Norway rat)	Sirt3	NP_001099783.1

Gene Ontology
Bibliography

Related articles in PubMed

SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism.
Wang T, Cao Y, Zheng Q, Tu J, Zhou W, He J, Zhong J, Chen Y, Wang J, Cai R, Zuo Y, Wei B, Fan Q, Yang J, Wu Y, Yi J, Li D, Liu M, Wang C, Zhou A, Li Y, Wu X, Yang W, Chin YE, Chen G, Cheng J
Molecular cell75(4)823-834.e5(2019 08)

Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis.
Li M, Chiang YL, Lyssiotis CA, Teater MR, Hong JY, Shen H, Wang L, Hu J, Jing H, Chen Z, Jain N, Duy C, Mistry SJ, Cerchietti L, Cross JR, Cantley LC, Green MR, Lin H, Melnick AM
Cancer cell35(6)916-931.e9(2019 Jun)

Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects.
Delbridge ARD, Kueh AJ, Ke F, Zamudio NM, El-Saafin F, Jansz N, Wang GY, Iminitoff M, Beck T, Haupt S, Hu Y, May RE, Whitehead L, Tai L, Chiang W, Herold MJ, Haupt Y, Smyth GK, Thomas T, Blewitt ME, Strasser A, Voss AK
Cell reports27(2)442-454.e5(2019 04)

SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice.
Liu Y, Cheng A, Li YJ, Yang Y, Kishimoto Y, Zhang S, Wang Y, Wan R, Raefsky SM, Lu D, Saito T, Saido T, Zhu J, Wu LJ, Mattson MP
Nature communications10(1)1886(2019 04)

Combined SIRT3 and SIRT5 deletion is associated with inner retinal dysfunction in a mouse model of type 1 diabetes.
Lin JB, Lin JB, Chen HC, Chen T, Apte RS
Scientific reports9(1)3799(2019 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Sirt3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sirt3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu40087	XM_006536222.4 Latest version!	Mus musculus sirtuin 3 (Sirt3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu40088	XM_006536223.4 Latest version!	Mus musculus sirtuin 3 (Sirt3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu22562	NM_001127351.1 Latest version!	Mus musculus sirtuin 3 (Sirt3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OMu22562	NM_022433.2 Latest version!	Mus musculus sirtuin 3 (Sirt3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OMu23005	NM_001177804.1 Latest version!	Mus musculus sirtuin 3 (Sirt3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$188.30 $269.00
View Old Accession Versions >>
OMu40088	XM_006536223.3	Mus musculus sirtuin 3 (Sirt3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu40087	XM_006536222.3	Mus musculus sirtuin 3 (Sirt3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sirt3 ( XM_006536222.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006536285.1 Mus musculus sirtuin 3 (Sirt3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu40087
Clone ID Related Accession (Same CDS sequence)	XM_006536222.3 , XM_006536222.4
Accession Version	XM_006536222.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	NAD-dependent protein deacetylase sirtuin-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006536222.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCTTG ACCCTCTAGG CGCCGTCGTC CTGCAGAGCA TCATGGCGCT AAGCGGTCGA 
CTGGCATTGG CCGCGCTCAG ACTGTGGGGT CCGGGAGGTG GGAGAAGGCC CATATCCCTC 
TGTGTGGGAG CCTCAGGCGG CTTTGGAGGT GGAGGAAGCA GTGAGAAGAA GTTTTCTCTG 
CAGGATGTAG CTGAGCTGCT TCGGACCAGA GCCTGCAGTA GGGTGGTGGT CATGGTGGGG 
GCCGGCATCA GCACACCCAG TGGCATCCCG GACTTCAGAT CCCCAGGGAG CGGCCTCTAC 
AGCAACCTTC AGCAGTATGA CATCCCGTAC CCTGAAGCCA TCTTTGAACT TGGCTTTTTC 
TTTCACAACC CCAAGCCCTT TTTCATGTTG GCCAAGGAGC TGTACCCTGG GCACTACAGG 
CCCAATGTCA CTCACTACTT CCTGAGGCTC CTCCACGACA AGGAGCTGCT TCTGCGGCTC 
TATACACAGA ACATCGACGG GCTTGAGAGA GCATCTGGGA TCCCTGCCTC AAAGCTGGTT 
GAAGCCCACG GGACCTTTGT AACAGCTACA TGCACGGTCT GTCGAAGGTC CTTCCCAGGG 
GAAGACATAT GGGTGGAGCC TTTTGCCAGC TTGTCTGAAG CAGTACAGAA ATCAGTGCCC 
CGACTGCTCA TCAATCGAGA CTTGGTGGGG CCGTTCGTTC TGAGTCCTCG AAGGAAAGAT 
GTGGTCCAGC TAGGGGATGT AGTTCATGGT GTGGAAAGGC TGGTGGACCT CCTGGGGTGG 
ACACAAGAAC TGCTGGATCT TATGCAGCGG GAACGTGGCA AGCTGGATGG ACAGGACAGA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006536285.1
CDS	293..1135
Translation	MALDPLGAVVLQSIMALSGRLALAALRLWGPGGGRRPISLCVGASGGFGGGGSSEKKFSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQRERGKLDGQDR

Target ORF information:

RefSeq Version	XM_006536222.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus sirtuin 3 (Sirt3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006536222.3

ORF Insert Sequence:

ATGGCGCTTG ACCCTCTAGG CGCCGTCGTC CTGCAGAGCA TCATGGCGCT AAGCGGTCGA 
CTGGCATTGG CCGCGCTCAG ACTGTGGGGT CCGGGAGGTG GGAGAAGGCC CATATCCCTC 
TGTGTGGGAG CCTCAGGCGG CTTTGGAGGT GGAGGAAGCA GTGAGAAGAA GTTTTCTCTG 
CAGGATGTAG CTGAGCTGCT TCGGACCAGA GCCTGCAGTA GGGTGGTGGT CATGGTGGGG 
GCCGGCATCA GCACACCCAG TGGCATCCCG GACTTCAGAT CCCCAGGGAG CGGCCTCTAC 
AGCAACCTTC AGCAGTATGA CATCCCGTAC CCTGAAGCCA TCTTTGAACT TGGCTTTTTC 
TTTCACAACC CCAAGCCCTT TTTCATGTTG GCCAAGGAGC TGTACCCTGG GCACTACAGG 
CCCAATGTCA CTCACTACTT CCTGAGGCTC CTCCACGACA AGGAGCTGCT TCTGCGGCTC 
TATACACAGA ACATCGACGG GCTTGAGAGA GCATCTGGGA TCCCTGCCTC AAAGCTGGTT 
GAAGCCCACG GGACCTTTGT AACAGCTACA TGCACGGTCT GTCGAAGGTC CTTCCCAGGG 
GAAGACATAT GGGTGGAGCC TTTTGCCAGC TTGTCTGAAG CAGTACAGAA ATCAGTGCCC 
CGACTGCTCA TCAATCGAGA CTTGGTGGGG CCGTTCGTTC TGAGTCCTCG AAGGAAAGAT 
GTGGTCCAGC TAGGGGATGT AGTTCATGGT GTGGAAAGGC TGGTGGACCT CCTGGGGTGG 
ACACAAGAAC TGCTGGATCT TATGCAGCGG GAACGTGGCA AGCTGGATGG ACAGGACAGA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sirt3 ( XM_006536222.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006536285.1 Mus musculus sirtuin 3 (Sirt3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu40087
Clone ID Related Accession (Same CDS sequence)	XM_006536222.3 , XM_006536222.4
Accession Version	XM_006536222.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	NAD-dependent protein deacetylase sirtuin-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006536222.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCTTG ACCCTCTAGG CGCCGTCGTC CTGCAGAGCA TCATGGCGCT AAGCGGTCGA 
CTGGCATTGG CCGCGCTCAG ACTGTGGGGT CCGGGAGGTG GGAGAAGGCC CATATCCCTC 
TGTGTGGGAG CCTCAGGCGG CTTTGGAGGT GGAGGAAGCA GTGAGAAGAA GTTTTCTCTG 
CAGGATGTAG CTGAGCTGCT TCGGACCAGA GCCTGCAGTA GGGTGGTGGT CATGGTGGGG 
GCCGGCATCA GCACACCCAG TGGCATCCCG GACTTCAGAT CCCCAGGGAG CGGCCTCTAC 
AGCAACCTTC AGCAGTATGA CATCCCGTAC CCTGAAGCCA TCTTTGAACT TGGCTTTTTC 
TTTCACAACC CCAAGCCCTT TTTCATGTTG GCCAAGGAGC TGTACCCTGG GCACTACAGG 
CCCAATGTCA CTCACTACTT CCTGAGGCTC CTCCACGACA AGGAGCTGCT TCTGCGGCTC 
TATACACAGA ACATCGACGG GCTTGAGAGA GCATCTGGGA TCCCTGCCTC AAAGCTGGTT 
GAAGCCCACG GGACCTTTGT AACAGCTACA TGCACGGTCT GTCGAAGGTC CTTCCCAGGG 
GAAGACATAT GGGTGGAGCC TTTTGCCAGC TTGTCTGAAG CAGTACAGAA ATCAGTGCCC 
CGACTGCTCA TCAATCGAGA CTTGGTGGGG CCGTTCGTTC TGAGTCCTCG AAGGAAAGAT 
GTGGTCCAGC TAGGGGATGT AGTTCATGGT GTGGAAAGGC TGGTGGACCT CCTGGGGTGG 
ACACAAGAAC TGCTGGATCT TATGCAGCGG GAACGTGGCA AGCTGGATGG ACAGGACAGA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006536285.1
CDS	40..882
Translation	MALDPLGAVVLQSIMALSGRLALAALRLWGPGGGRRPISLCVGASGGFGGGGSSEKKFSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQRERGKLDGQDR

Target ORF information:

RefSeq Version	XM_006536222.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus sirtuin 3 (Sirt3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006536222.4

ORF Insert Sequence:

ATGGCGCTTG ACCCTCTAGG CGCCGTCGTC CTGCAGAGCA TCATGGCGCT AAGCGGTCGA 
CTGGCATTGG CCGCGCTCAG ACTGTGGGGT CCGGGAGGTG GGAGAAGGCC CATATCCCTC 
TGTGTGGGAG CCTCAGGCGG CTTTGGAGGT GGAGGAAGCA GTGAGAAGAA GTTTTCTCTG 
CAGGATGTAG CTGAGCTGCT TCGGACCAGA GCCTGCAGTA GGGTGGTGGT CATGGTGGGG 
GCCGGCATCA GCACACCCAG TGGCATCCCG GACTTCAGAT CCCCAGGGAG CGGCCTCTAC 
AGCAACCTTC AGCAGTATGA CATCCCGTAC CCTGAAGCCA TCTTTGAACT TGGCTTTTTC 
TTTCACAACC CCAAGCCCTT TTTCATGTTG GCCAAGGAGC TGTACCCTGG GCACTACAGG 
CCCAATGTCA CTCACTACTT CCTGAGGCTC CTCCACGACA AGGAGCTGCT TCTGCGGCTC 
TATACACAGA ACATCGACGG GCTTGAGAGA GCATCTGGGA TCCCTGCCTC AAAGCTGGTT 
GAAGCCCACG GGACCTTTGT AACAGCTACA TGCACGGTCT GTCGAAGGTC CTTCCCAGGG 
GAAGACATAT GGGTGGAGCC TTTTGCCAGC TTGTCTGAAG CAGTACAGAA ATCAGTGCCC 
CGACTGCTCA TCAATCGAGA CTTGGTGGGG CCGTTCGTTC TGAGTCCTCG AAGGAAAGAT 
GTGGTCCAGC TAGGGGATGT AGTTCATGGT GTGGAAAGGC TGGTGGACCT CCTGGGGTGG 
ACACAAGAAC TGCTGGATCT TATGCAGCGG GAACGTGGCA AGCTGGATGG ACAGGACAGA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sirt3 ( XM_006536223.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006536286.1 Mus musculus sirtuin 3 (Sirt3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu40088
Clone ID Related Accession (Same CDS sequence)	XM_006536223.3 , XM_006536223.4
Accession Version	XM_006536223.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	NAD-dependent protein deacetylase sirtuin-3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006536223.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGGGG CCGGCATCAG CACACCCAGT GGCATCCCGG ACTTCAGATC CCCAGGGAGC 
GGCCTCTACA GCAACCTTCA GCAGTATGAC ATCCCGTACC CTGAAGCCAT CTTTGAACTT 
GGCTTTTTCT TTCACAACCC CAAGCCCTTT TTCATGTTGG CCAAGGAGCT GTACCCTGGG 
CACTACAGGC CCAATGTCAC TCACTACTTC CTGAGGCTCC TCCACGACAA GGAGCTGCTT 
CTGCGGCTCT ATACACAGAA CATCGACGGG CTTGAGAGAG CATCTGGGAT CCCTGCCTCA 
AAGCTGGTTG AAGCCCACGG GACCTTTGTA ACAGCTACAT GCACGGTCTG TCGAAGGTCC 
TTCCCAGGGG AAGACATATG GGTGGAGCCT TTTGCCAGCT TGTCTGAAGC AGTACAGAAA 
TCAGTGCCCC GACTGCTCAT CAATCGAGAC TTGGTGGGGC CGTTCGTTCT GAGTCCTCGA 
AGGAAAGATG TGGTCCAGCT AGGGGATGTA GTTCATGGTG TGGAAAGGCT GGTGGACCTC 
CTGGGGTGGA CACAAGAACT GCTGGATCTT ATGCAGCGGG AACGTGGCAA GCTGGATGGA 
CAGGACAGAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006536286.1
CDS	240..851
Translation	MVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQRERGKLDGQDR

Target ORF information:

RefSeq Version	XM_006536223.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus sirtuin 3 (Sirt3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006536223.3

ORF Insert Sequence:

ATGGTGGGGG CCGGCATCAG CACACCCAGT GGCATCCCGG ACTTCAGATC CCCAGGGAGC 
GGCCTCTACA GCAACCTTCA GCAGTATGAC ATCCCGTACC CTGAAGCCAT CTTTGAACTT 
GGCTTTTTCT TTCACAACCC CAAGCCCTTT TTCATGTTGG CCAAGGAGCT GTACCCTGGG 
CACTACAGGC CCAATGTCAC TCACTACTTC CTGAGGCTCC TCCACGACAA GGAGCTGCTT 
CTGCGGCTCT ATACACAGAA CATCGACGGG CTTGAGAGAG CATCTGGGAT CCCTGCCTCA 
AAGCTGGTTG AAGCCCACGG GACCTTTGTA ACAGCTACAT GCACGGTCTG TCGAAGGTCC 
TTCCCAGGGG AAGACATATG GGTGGAGCCT TTTGCCAGCT TGTCTGAAGC AGTACAGAAA 
TCAGTGCCCC GACTGCTCAT CAATCGAGAC TTGGTGGGGC CGTTCGTTCT GAGTCCTCGA 
AGGAAAGATG TGGTCCAGCT AGGGGATGTA GTTCATGGTG TGGAAAGGCT GGTGGACCTC 
CTGGGGTGGA CACAAGAACT GCTGGATCTT ATGCAGCGGG AACGTGGCAA GCTGGATGGA 
CAGGACAGAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sirt3 ( XM_006536223.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006536286.1 Mus musculus sirtuin 3 (Sirt3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu40088
Clone ID Related Accession (Same CDS sequence)	XM_006536223.3 , XM_006536223.4
Accession Version	XM_006536223.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	NAD-dependent protein deacetylase sirtuin-3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006536223.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGGGG CCGGCATCAG CACACCCAGT GGCATCCCGG ACTTCAGATC CCCAGGGAGC 
GGCCTCTACA GCAACCTTCA GCAGTATGAC ATCCCGTACC CTGAAGCCAT CTTTGAACTT 
GGCTTTTTCT TTCACAACCC CAAGCCCTTT TTCATGTTGG CCAAGGAGCT GTACCCTGGG 
CACTACAGGC CCAATGTCAC TCACTACTTC CTGAGGCTCC TCCACGACAA GGAGCTGCTT 
CTGCGGCTCT ATACACAGAA CATCGACGGG CTTGAGAGAG CATCTGGGAT CCCTGCCTCA 
AAGCTGGTTG AAGCCCACGG GACCTTTGTA ACAGCTACAT GCACGGTCTG TCGAAGGTCC 
TTCCCAGGGG AAGACATATG GGTGGAGCCT TTTGCCAGCT TGTCTGAAGC AGTACAGAAA 
TCAGTGCCCC GACTGCTCAT CAATCGAGAC TTGGTGGGGC CGTTCGTTCT GAGTCCTCGA 
AGGAAAGATG TGGTCCAGCT AGGGGATGTA GTTCATGGTG TGGAAAGGCT GGTGGACCTC 
CTGGGGTGGA CACAAGAACT GCTGGATCTT ATGCAGCGGG AACGTGGCAA GCTGGATGGA 
CAGGACAGAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006536286.1
CDS	258..869
Translation	MVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQRERGKLDGQDR

Target ORF information:

RefSeq Version	XM_006536223.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus sirtuin 3 (Sirt3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006536223.4

ORF Insert Sequence:

ATGGTGGGGG CCGGCATCAG CACACCCAGT GGCATCCCGG ACTTCAGATC CCCAGGGAGC 
GGCCTCTACA GCAACCTTCA GCAGTATGAC ATCCCGTACC CTGAAGCCAT CTTTGAACTT 
GGCTTTTTCT TTCACAACCC CAAGCCCTTT TTCATGTTGG CCAAGGAGCT GTACCCTGGG 
CACTACAGGC CCAATGTCAC TCACTACTTC CTGAGGCTCC TCCACGACAA GGAGCTGCTT 
CTGCGGCTCT ATACACAGAA CATCGACGGG CTTGAGAGAG CATCTGGGAT CCCTGCCTCA 
AAGCTGGTTG AAGCCCACGG GACCTTTGTA ACAGCTACAT GCACGGTCTG TCGAAGGTCC 
TTCCCAGGGG AAGACATATG GGTGGAGCCT TTTGCCAGCT TGTCTGAAGC AGTACAGAAA 
TCAGTGCCCC GACTGCTCAT CAATCGAGAC TTGGTGGGGC CGTTCGTTCT GAGTCCTCGA 
AGGAAAGATG TGGTCCAGCT AGGGGATGTA GTTCATGGTG TGGAAAGGCT GGTGGACCTC 
CTGGGGTGGA CACAAGAACT GCTGGATCTT ATGCAGCGGG AACGTGGCAA GCTGGATGGA 
CAGGACAGAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sirt3 ( NM_001127351.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001120823.1 Mus musculus sirtuin 3 (Sirt3), transcript variant 2, mRNA.

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CloneID	OMu22562
Clone ID Related Accession (Same CDS sequence)	NM_001127351.1 , NM_022433.2
Accession Version	NM_001127351.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576339200000
Organism	Mus musculus(house mouse)
Product	NAD-dependent protein deacetylase sirtuin-3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF299339.1, AF299338.1, CT010402.1 and BF681854.1. Transcript Variant: This variant (2) has an additional segment, resulting in a downstream AUG start codon, as compared to variant 3. The resulting isoform (1) is shorter at the N-terminus, as compared to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF299339.1, AK075861.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGGTGGGGG CCGGCATCAG CACACCCAGT GGCATCCCGG ACTTCAGATC CCCAGGGAGC 
GGCCTCTACA GCAACCTTCA GCAGTATGAC ATCCCGTACC CTGAAGCCAT CTTTGAACTT 
GGCTTTTTCT TTCACAACCC CAAGCCCTTT TTCATGTTGG CCAAGGAGCT GTACCCTGGG 
CACTACAGGC CCAATGTCAC TCACTACTTC CTGAGGCTCC TCCACGACAA GGAGCTGCTT 
CTGCGGCTCT ATACACAGAA CATCGACGGG CTTGAGAGAG CATCTGGGAT CCCTGCCTCA 
AAGCTGGTTG AAGCCCACGG GACCTTTGTA ACAGCTACAT GCACGGTCTG TCGAAGGTCC 
TTCCCAGGGG AAGACATATG GGCTGATGTG ATGGCGGACA GGGTGCCCCG CTGCCCTGTC 
TGTACTGGCG TTGTGAAACC CGACATTGTG TTCTTTGGGG AGCAGCTGCC TGCAAGGTTC 
CTACTCCATA TGGCTGACTT CGCTTTGGCA GATCTGCTAC TCATTCTTGG GACCTCCCTG 
GAGGTGGAGC CTTTTGCCAG CTTGTCTGAA GCAGTACAGA AATCAGTGCC CCGACTGCTC 
ATCAATCGAG ACTTGGTGGG GCCGTTCGTT CTGAGTCCTC GAAGGAAAGA TGTGGTCCAG 
CTAGGGGATG TAGTTCATGG TGTGGAAAGG CTGGTGGACC TCCTGGGGTG GACACAAGAA 
CTGCTGGATC TTATGCAGCG GGAACGTGGC AAGCTGGATG GACAGGACAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001120823.1
CDS	250..1023
Translation	MVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVPRCPVCTGVVKPDIVFFGEQLPARFLLHMADFALADLLLILGTSLEVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQRERGKLDGQDR

Target ORF information:

RefSeq Version	NM_001127351.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus sirtuin 3 (Sirt3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127351.1

ORF Insert Sequence:

ATGGTGGGGG CCGGCATCAG CACACCCAGT GGCATCCCGG ACTTCAGATC CCCAGGGAGC 
GGCCTCTACA GCAACCTTCA GCAGTATGAC ATCCCGTACC CTGAAGCCAT CTTTGAACTT 
GGCTTTTTCT TTCACAACCC CAAGCCCTTT TTCATGTTGG CCAAGGAGCT GTACCCTGGG 
CACTACAGGC CCAATGTCAC TCACTACTTC CTGAGGCTCC TCCACGACAA GGAGCTGCTT 
CTGCGGCTCT ATACACAGAA CATCGACGGG CTTGAGAGAG CATCTGGGAT CCCTGCCTCA 
AAGCTGGTTG AAGCCCACGG GACCTTTGTA ACAGCTACAT GCACGGTCTG TCGAAGGTCC 
TTCCCAGGGG AAGACATATG GGCTGATGTG ATGGCGGACA GGGTGCCCCG CTGCCCTGTC 
TGTACTGGCG TTGTGAAACC CGACATTGTG TTCTTTGGGG AGCAGCTGCC TGCAAGGTTC 
CTACTCCATA TGGCTGACTT CGCTTTGGCA GATCTGCTAC TCATTCTTGG GACCTCCCTG 
GAGGTGGAGC CTTTTGCCAG CTTGTCTGAA GCAGTACAGA AATCAGTGCC CCGACTGCTC 
ATCAATCGAG ACTTGGTGGG GCCGTTCGTT CTGAGTCCTC GAAGGAAAGA TGTGGTCCAG 
CTAGGGGATG TAGTTCATGG TGTGGAAAGG CTGGTGGACC TCCTGGGGTG GACACAAGAA 
CTGCTGGATC TTATGCAGCG GGAACGTGGC AAGCTGGATG GACAGGACAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sirt3 ( NM_022433.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_071878.2 Mus musculus sirtuin 3 (Sirt3), transcript variant 1, mRNA.

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CloneID	OMu22562
Clone ID Related Accession (Same CDS sequence)	NM_001127351.1 , NM_022433.2
Accession Version	NM_022433.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574092800000
Organism	Mus musculus(house mouse)
Product	NAD-dependent protein deacetylase sirtuin-3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF299338.1, CT010402.1 and BF681854.1. On May 14, 2008 this sequence version replaced NM_022433.1. Transcript Variant: This variant (1) has an alternate 5' exon and an additional segment, resulting in a downstream AUG start codon, as compared to variant 3. The resulting isoform (1) is shorter at the N-terminus, as compared to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF299338.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGGTGGGGG CCGGCATCAG CACACCCAGT GGCATCCCGG ACTTCAGATC CCCAGGGAGC 
GGCCTCTACA GCAACCTTCA GCAGTATGAC ATCCCGTACC CTGAAGCCAT CTTTGAACTT 
GGCTTTTTCT TTCACAACCC CAAGCCCTTT TTCATGTTGG CCAAGGAGCT GTACCCTGGG 
CACTACAGGC CCAATGTCAC TCACTACTTC CTGAGGCTCC TCCACGACAA GGAGCTGCTT 
CTGCGGCTCT ATACACAGAA CATCGACGGG CTTGAGAGAG CATCTGGGAT CCCTGCCTCA 
AAGCTGGTTG AAGCCCACGG GACCTTTGTA ACAGCTACAT GCACGGTCTG TCGAAGGTCC 
TTCCCAGGGG AAGACATATG GGCTGATGTG ATGGCGGACA GGGTGCCCCG CTGCCCTGTC 
TGTACTGGCG TTGTGAAACC CGACATTGTG TTCTTTGGGG AGCAGCTGCC TGCAAGGTTC 
CTACTCCATA TGGCTGACTT CGCTTTGGCA GATCTGCTAC TCATTCTTGG GACCTCCCTG 
GAGGTGGAGC CTTTTGCCAG CTTGTCTGAA GCAGTACAGA AATCAGTGCC CCGACTGCTC 
ATCAATCGAG ACTTGGTGGG GCCGTTCGTT CTGAGTCCTC GAAGGAAAGA TGTGGTCCAG 
CTAGGGGATG TAGTTCATGG TGTGGAAAGG CTGGTGGACC TCCTGGGGTG GACACAAGAA 
CTGCTGGATC TTATGCAGCG GGAACGTGGC AAGCTGGATG GACAGGACAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071878.2
CDS	295..1068
Translation	MVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVPRCPVCTGVVKPDIVFFGEQLPARFLLHMADFALADLLLILGTSLEVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQRERGKLDGQDR

Target ORF information:

RefSeq Version	NM_022433.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus sirtuin 3 (Sirt3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022433.2

ORF Insert Sequence:

ATGGTGGGGG CCGGCATCAG CACACCCAGT GGCATCCCGG ACTTCAGATC CCCAGGGAGC 
GGCCTCTACA GCAACCTTCA GCAGTATGAC ATCCCGTACC CTGAAGCCAT CTTTGAACTT 
GGCTTTTTCT TTCACAACCC CAAGCCCTTT TTCATGTTGG CCAAGGAGCT GTACCCTGGG 
CACTACAGGC CCAATGTCAC TCACTACTTC CTGAGGCTCC TCCACGACAA GGAGCTGCTT 
CTGCGGCTCT ATACACAGAA CATCGACGGG CTTGAGAGAG CATCTGGGAT CCCTGCCTCA 
AAGCTGGTTG AAGCCCACGG GACCTTTGTA ACAGCTACAT GCACGGTCTG TCGAAGGTCC 
TTCCCAGGGG AAGACATATG GGCTGATGTG ATGGCGGACA GGGTGCCCCG CTGCCCTGTC 
TGTACTGGCG TTGTGAAACC CGACATTGTG TTCTTTGGGG AGCAGCTGCC TGCAAGGTTC 
CTACTCCATA TGGCTGACTT CGCTTTGGCA GATCTGCTAC TCATTCTTGG GACCTCCCTG 
GAGGTGGAGC CTTTTGCCAG CTTGTCTGAA GCAGTACAGA AATCAGTGCC CCGACTGCTC 
ATCAATCGAG ACTTGGTGGG GCCGTTCGTT CTGAGTCCTC GAAGGAAAGA TGTGGTCCAG 
CTAGGGGATG TAGTTCATGG TGTGGAAAGG CTGGTGGACC TCCTGGGGTG GACACAAGAA 
CTGCTGGATC TTATGCAGCG GGAACGTGGC AAGCTGGATG GACAGGACAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sirt3 ( NM_001177804.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001171275.1 Mus musculus sirtuin 3 (Sirt3), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu23005
Clone ID Related Accession (Same CDS sequence)	NM_001177804.1
Accession Version	NM_001177804.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576339200000
Organism	Mus musculus(house mouse)
Product	NAD-dependent protein deacetylase sirtuin-3 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB953804.1, AK075861.1 and BF681854.1. Transcript Variant: This variant (3) encodes the longer isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU886466.1, FJ621493.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGGCGCTTG ACCCTCTAGG CGCCGTCGTC CTGCAGAGCA TCATGGCGCT AAGCGGTCGA 
CTGGCATTGG CCGCGCTCAG ACTGTGGGGT CCGGGAGGTG GGAGAAGGCC CATATCCCTC 
TGTGTGGGAG CCTCAGGCGG CTTTGGAGGT GGAGGAAGCA GTGAGAAGAA GTTTTCTCTG 
CAGGATGTAG CTGAGCTGCT TCGGACCAGA GCCTGCAGTA GGGTGGTGGT CATGGTGGGG 
GCCGGCATCA GCACACCCAG TGGCATCCCG GACTTCAGAT CCCCAGGGAG CGGCCTCTAC 
AGCAACCTTC AGCAGTATGA CATCCCGTAC CCTGAAGCCA TCTTTGAACT TGGCTTTTTC 
TTTCACAACC CCAAGCCCTT TTTCATGTTG GCCAAGGAGC TGTACCCTGG GCACTACAGG 
CCCAATGTCA CTCACTACTT CCTGAGGCTC CTCCACGACA AGGAGCTGCT TCTGCGGCTC 
TATACACAGA ACATCGACGG GCTTGAGAGA GCATCTGGGA TCCCTGCCTC AAAGCTGGTT 
GAAGCCCACG GGACCTTTGT AACAGCTACA TGCACGGTCT GTCGAAGGTC CTTCCCAGGG 
GAAGACATAT GGGCTGATGT GATGGCGGAC AGGGTGCCCC GCTGCCCTGT CTGTACTGGC 
GTTGTGAAAC CCGACATTGT GTTCTTTGGG GAGCAGCTGC CTGCAAGGTT CCTACTCCAT 
ATGGCTGACT TCGCTTTGGC AGATCTGCTA CTCATTCTTG GGACCTCCCT GGAGGTGGAG 
CCTTTTGCCA GCTTGTCTGA AGCAGTACAG AAATCAGTGC CCCGACTGCT CATCAATCGA 
GACTTGGTGG GGCCGTTCGT TCTGAGTCCT CGAAGGAAAG ATGTGGTCCA GCTAGGGGAT 
GTAGTTCATG GTGTGGAAAG GCTGGTGGAC CTCCTGGGGT GGACACAAGA ACTGCTGGAT 
CTTATGCAGC GGGAACGTGG CAAGCTGGAT GGACAGGACA GATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171275.1
CDS	11..1015
Translation	MALDPLGAVVLQSIMALSGRLALAALRLWGPGGGRRPISLCVGASGGFGGGGSSEKKFSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVPRCPVCTGVVKPDIVFFGEQLPARFLLHMADFALADLLLILGTSLEVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQRERGKLDGQDR

Target ORF information:

RefSeq Version	NM_001177804.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus sirtuin 3 (Sirt3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001177804.1

ORF Insert Sequence:

ATGGCGCTTG ACCCTCTAGG CGCCGTCGTC CTGCAGAGCA TCATGGCGCT AAGCGGTCGA 
CTGGCATTGG CCGCGCTCAG ACTGTGGGGT CCGGGAGGTG GGAGAAGGCC CATATCCCTC 
TGTGTGGGAG CCTCAGGCGG CTTTGGAGGT GGAGGAAGCA GTGAGAAGAA GTTTTCTCTG 
CAGGATGTAG CTGAGCTGCT TCGGACCAGA GCCTGCAGTA GGGTGGTGGT CATGGTGGGG 
GCCGGCATCA GCACACCCAG TGGCATCCCG GACTTCAGAT CCCCAGGGAG CGGCCTCTAC 
AGCAACCTTC AGCAGTATGA CATCCCGTAC CCTGAAGCCA TCTTTGAACT TGGCTTTTTC 
TTTCACAACC CCAAGCCCTT TTTCATGTTG GCCAAGGAGC TGTACCCTGG GCACTACAGG 
CCCAATGTCA CTCACTACTT CCTGAGGCTC CTCCACGACA AGGAGCTGCT TCTGCGGCTC 
TATACACAGA ACATCGACGG GCTTGAGAGA GCATCTGGGA TCCCTGCCTC AAAGCTGGTT 
GAAGCCCACG GGACCTTTGT AACAGCTACA TGCACGGTCT GTCGAAGGTC CTTCCCAGGG 
GAAGACATAT GGGCTGATGT GATGGCGGAC AGGGTGCCCC GCTGCCCTGT CTGTACTGGC 
GTTGTGAAAC CCGACATTGT GTTCTTTGGG GAGCAGCTGC CTGCAAGGTT CCTACTCCAT 
ATGGCTGACT TCGCTTTGGC AGATCTGCTA CTCATTCTTG GGACCTCCCT GGAGGTGGAG 
CCTTTTGCCA GCTTGTCTGA AGCAGTACAG AAATCAGTGC CCCGACTGCT CATCAATCGA 
GACTTGGTGG GGCCGTTCGT TCTGAGTCCT CGAAGGAAAG ATGTGGTCCA GCTAGGGGAT 
GTAGTTCATG GTGTGGAAAG GCTGGTGGAC CTCCTGGGGT GGACACAAGA ACTGCTGGAT 
CTTATGCAGC GGGAACGTGG CAAGCTGGAT GGACAGGACA GATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism.
Molecular cell75(4)823-834.e5(2019 08)
Wang T,Cao Y,Zheng Q,Tu J,Zhou W,He J,Zhong J,Chen Y,Wang J,Cai R,Zuo Y,Wei B,Fan Q,Yang J,Wu Y,Yi J,Li D,Liu M,Wang C,Zhou A,Li Y,Wu X,Yang W,Chin YE,Chen G,Cheng J

Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis.
Cancer cell35(6)916-931.e9(2019 Jun)
Li M,Chiang YL,Lyssiotis CA,Teater MR,Hong JY,Shen H,Wang L,Hu J,Jing H,Chen Z,Jain N,Duy C,Mistry SJ,Cerchietti L,Cross JR,Cantley LC,Green MR,Lin H,Melnick AM

Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects.
Cell reports27(2)442-454.e5(2019 04)
Delbridge ARD,Kueh AJ,Ke F,Zamudio NM,El-Saafin F,Jansz N,Wang GY,Iminitoff M,Beck T,Haupt S,Hu Y,May RE,Whitehead L,Tai L,Chiang W,Herold MJ,Haupt Y,Smyth GK,Thomas T,Blewitt ME,Strasser A,Voss AK

SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice.
Nature communications10(1)1886(2019 04)
Liu Y,Cheng A,Li YJ,Yang Y,Kishimoto Y,Zhang S,Wang Y,Wan R,Raefsky SM,Lu D,Saito T,Saido T,Zhu J,Wu LJ,Mattson MP

Combined SIRT3 and SIRT5 deletion is associated with inner retinal dysfunction in a mouse model of type 1 diabetes.
Scientific reports9(1)3799(2019 Mar)
Lin JB,Lin JB,Chen HC,Chen T,Apte RS

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Sirt3 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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