Ube2l6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ube2l6
Entrez Gene ID	56791
Full Name	ubiquitin-conjugating enzyme E2L 6
Synonyms	2810489I21Rik,RIG-B,UBCH8,Ubce8,Ubcm8
General protein information	Preferred Names ubiquitin-conjugating enzyme E2L 6 Names ubiquitin/ISG15-conjugating enzyme E2 L6 E2 ubiquitin conjugating enzyme E2 ubiquitin-conjugating enzyme L6 ubiquitin carrier protein L6 ubiquitin-conjugating enzyme 8 ubiquitin-protein ligase L6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 D

mRNA and Protein(s)

mRNA	Protein	Name
NM_019949.2	NP_064333.2	ubiquitin/ISG15-conjugating enzyme E2 L6

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Ube2l6	NP_001019926.1
Homo sapiens (human)	UBE2L6	NP_004214.1
Canis lupus familiaris (dog)	UBE2L6	XP_533174.1
Pan troglodytes (chimpanzee)	UBE2L6	XP_003318028.1
Bos taurus (cattle)	UBE2L6	NP_001092387.1
Mus musculus (house mouse)	Ube2l6	NP_064333.2

Gene Ontology
Bibliography

Related articles in PubMed

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

Identification of a loss-of-function mutation in Ube2l6 associated with obesity resistance.
Marcelin G, Liu SM, Schwartz GJ, Chua SC Jr
Diabetes62(8)2784-95(2013 Aug)

A novel role for ATM in regulating proteasome-mediated protein degradation through suppression of the ISG15 conjugation pathway.
Wood LM, Sankar S, Reed RE, Haas AL, Liu LF, McKinnon P, Desai SD
PloS one6(1)e16422(2011 Jan)

TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels.
Makki MS, Heinzel T, Englert C
Nucleic acids research36(12)4067-78(2008 Jul)

Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.
Giannakopoulos NV, Luo JK, Papov V, Zou W, Lenschow DJ, Jacobs BS, Borden EC, Li J, Virgin HW, Zhang DE
Biochemical and biophysical research communications336(2)496-506(2005 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ube2l6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ube2l6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu11918	NM_019949.2 Latest version!	Mus musculus ubiquitin-conjugating enzyme E2L 6 (Ube2l6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ube2l6 ( NM_019949.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_064333.2 Mus musculus ubiquitin-conjugating enzyme E2L 6 (Ube2l6), mRNA.

Price & Availability↑

CloneID	OMu11918
Clone ID Related Accession (Same CDS sequence)	NM_019949.2
Accession Version	NM_019949.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550592000000
Organism	Mus musculus(house mouse)
Product	ubiquitin/ISG15-conjugating enzyme E2 L6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK152113.1 and CJ300190.1. On Nov 20, 2008 this sequence version replaced NM_019949.1. ##Evidence-Data-START## Transcript exon combination :: BC008238.1, AK152113.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGGCCA GCAAGCGAGT GGCGAAAGAG CTGGAGAGTC TTTCGAAGGA GCTGCCGCCA 
TACCTTCGCC AACTGTCTAG TGACGATGCC AATGTGCTTG TGTGGCACAT GCTCCTGCTG 
CCAGACCAGC TTCCCTATGG CCTCAAAGCC TTCCAAGTGC GGATTGATTT CCCCAGGGAG 
TATCCATTCA AGCCTCCCAC TTTGAGATTC ACCACCAAGA TCTACCACCC CAACGTCAGG 
GAGGATGGTC TGGTGTGCCT GCCCCTCATC AGCAATGAGA ACTGGAAGCC TTACACCAAG 
CCTTATCAAG TCTTGGAGGC CCTCAATGTG CTGGTGAGTA AACCGAATCT GGAAGAGCCT 
GTGCGTCTGG AACTTGCTGA CCTCCTGACT CAGAACCCGG AGATGTTCAG GAAGAAGGCA 
GAAGAGTTCA CCCTTAAATT CGGAGTGGAC CGGCCCTCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064333.2
CDS	79..540
Translation	MMASKRVAKELESLSKELPPYLRQLSSDDANVLVWHMLLLPDQLPYGLKAFQVRIDFPREYPFKPPTLRFTTKIYHPNVREDGLVCLPLISNENWKPYTKPYQVLEALNVLVSKPNLEEPVRLELADLLTQNPEMFRKKAEEFTLKFGVDRPS

Target ORF information:

RefSeq Version	NM_019949.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ubiquitin-conjugating enzyme E2L 6 (Ube2l6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019949.2

ORF Insert Sequence:

ATGATGGCCA GCAAGCGAGT GGCGAAAGAG CTGGAGAGTC TTTCGAAGGA GCTGCCGCCA 
TACCTTCGCC AACTGTCTAG TGACGATGCC AATGTGCTTG TGTGGCACAT GCTCCTGCTG 
CCAGACCAGC TTCCCTATGG CCTCAAAGCC TTCCAAGTGC GGATTGATTT CCCCAGGGAG 
TATCCATTCA AGCCTCCCAC TTTGAGATTC ACCACCAAGA TCTACCACCC CAACGTCAGG 
GAGGATGGTC TGGTGTGCCT GCCCCTCATC AGCAATGAGA ACTGGAAGCC TTACACCAAG 
CCTTATCAAG TCTTGGAGGC CCTCAATGTG CTGGTGAGTA AACCGAATCT GGAAGAGCCT 
GTGCGTCTGG AACTTGCTGA CCTCCTGACT CAGAACCCGG AGATGTTCAG GAAGAAGGCA 
GAAGAGTTCA CCCTTAAATT CGGAGTGGAC CGGCCCTCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

Identification of a loss-of-function mutation in Ube2l6 associated with obesity resistance.
Diabetes62(8)2784-95(2013 Aug)
Marcelin G,Liu SM,Schwartz GJ,Chua SC Jr

A novel role for ATM in regulating proteasome-mediated protein degradation through suppression of the ISG15 conjugation pathway.
PloS one6(1)e16422(2011 Jan)
Wood LM,Sankar S,Reed RE,Haas AL,Liu LF,McKinnon P,Desai SD

TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels.
Nucleic acids research36(12)4067-78(2008 Jul)
Makki MS,Heinzel T,Englert C

Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.
Biochemical and biophysical research communications336(2)496-506(2005 Oct)
Giannakopoulos NV,Luo JK,Papov V,Zou W,Lenschow DJ,Jacobs BS,Borden EC,Li J,Virgin HW,Zhang DE

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Ube2l6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM