Irf6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Irf6
Entrez Gene ID	54139
Full Name	interferon regulatory factor 6
Synonyms	AI876454,E230028I05Rik,mirf6
General protein information	Preferred Names interferon regulatory factor 6 Names interferon regulatory factor 6 IRF-6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 H6\|1 97.6 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_016851.2	NP_058547.2	interferon regulatory factor 6
XM_006497263.3	XP_006497326.1	interferon regulatory factor 6 isoform X1
XM_006497262.3	XP_006497325.1	interferon regulatory factor 6 isoform X1
XM_006497262.4	XP_006497325.1	interferon regulatory factor 6 isoform X1
XM_006497263.4	XP_006497326.1	interferon regulatory factor 6 isoform X1

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	IRF6	XP_001110321.1
Bos taurus (cattle)	IRF6	NP_001070402.1
Gallus gallus (chicken)	IRF6	XP_417990.4
Homo sapiens (human)	IRF6	NP_006138.1
Canis lupus familiaris (dog)	IRF6	XP_005622392.1
Mus musculus (house mouse)	Irf6	NP_058547.2
Xenopus tropicalis (tropical clawed frog)	irf6	NP_001025493.1
Danio rerio (zebrafish)	irf6	NP_956892.1
Pan troglodytes (chimpanzee)	IRF6	XP_514168.2
Rattus norvegicus (Norway rat)	Irf6	NP_001102329.1

Gene Ontology
Bibliography

Related articles in PubMed

The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.
Oberbeck N, Pham VC, Webster JD, Reja R, Huang CS, Zhang Y, Roose-Girma M, Warming S, Li Q, Birnberg A, Wong W, Sandoval W, Kőműves LG, Yu K, Dugger DL, Maltzman A, Newton K, Dixit VM
Nature574(7777)249-253(2019 10)

The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation.
Kousa YA, Zhu H, Fakhouri WD, Lei Y, Kinoshita A, Roushangar RR, Patel NK, Agopian AJ, Yang W, Leslie EJ, Busch TD, Mansour TA, Li X, Smith AL, Li EB, Sharma DB, Williams TJ, Chai Y, Amendt BA, Liao EC, Mitchell LE, Bassuk AG, Gregory S, Ashley-Koch A, Shaw GM, Finnell RH, Schutte BC
Human molecular genetics28(10)1726-1737(2019 05)

A cleft lip and palate gene, Irf6, is involved in osteoblast differentiation of craniofacial bone.
Thompson J, Mendoza F, Tan E, Bertol JW, Gaggar AS, Jun G, Biguetti C, Fakhouri WD
Developmental dynamics : an official publication of the American Association of Anatomists248(3)221-232(2019 03)

IRF6 and AP2A Interaction Regulates Epidermal Development.
Kousa YA, Fuller E, Schutte BC
The Journal of investigative dermatology138(12)2578-2588(2018 12)

Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion.
Li J, Yuan Y, He J, Feng J, Han X, Jing J, Ho TV, Xu J, Chai Y
Developmental biology441(1)191-203(2018 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Irf6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Irf6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10782	NM_016851.2 Latest version!	Mus musculus interferon regulatory factor 6 (Irf6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu10782	XM_006497262.4 Latest version!	Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu10782	XM_006497263.4 Latest version!	Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OMu10782	XM_006497262.3	Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu10782	XM_006497263.3	Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Irf6 ( NM_016851.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_058547.2 Mus musculus interferon regulatory factor 6 (Irf6), mRNA.

Price & Availability↑

CloneID	OMu10782
Clone ID Related Accession (Same CDS sequence)	NM_016851.2 , XM_006497263.3 , XM_006497262.3 , XM_006497262.4 , XM_006497263.4
Accession Version	NM_016851.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1578067200000
Organism	Mus musculus(house mouse)
Product	interferon regulatory factor 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY100044.1, AK143954.1 and BP774622.1. On Sep 7, 2006 this sequence version replaced NM_016851.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC008515.1, U73029.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCTCC ACCCTCGAAG AGTCCGGCTG AAGCCCTGGC TGGTGGCCCA GGTGGACAGT 
GGCCTCTACC CTGGTCTCAT CTGGCTACAC AGAGATTCCA AACGCTTCCA GATCCCCTGG 
AAACATGCCA CGCGGCACAG CCCCCAACAA GAGGAAGAAA ACACCATTTT TAAGGCTTGG 
GCTGTGGAGA CCGGAAAGTA CCAGGAAGGG GTAGACGATC CTGACCCAGC TAAATGGAAG 
GCTCAGCTCC GCTGTGCTCT CAACAAAAGC AGGGAGTTCA ACTTGATGTA CGATGGCACC 
AAGGAAGTGC CCATGAATCC TGTGAAGATC TATCAAGTGT GTGACATCCC CCAGACCCAG 
GGCTCTGTCA TTAATCCAGG ATCCACAGGG TCTGCTCCTT GGGATGAGAA AGATAATGAT 
GTGGATGAAG ATGAGGAGGA GGATGAACTT GAGCAGTCAC AGCACCATGT CCCCATCCAG 
GACACCTTCC CCTTCCTGAA CATCAACGGT TCTCCCATGG CGCCAGCCAG CGTGGGCAAC 
TGCAGTGTGG GAAACTGCAG CCCCGAATCA GTGTGGCCCA AAACAGAACC TCTGGAGATG 
GAAGTACCCC AGGCACCCAT TCAACCCTTC TACAGTTCTC CAGAGCTATG GATCAGCTCT 
CTCCCCATGA CTGACTTGGA CATCAAATTT CAGTATCGTG GGAAGGAGTA TGGGCAAACT 
ATGACGGTGA GCAACCCCCA GGGCTGCCGG CTCTTCTATG GGGACCTGGG CCCCATGCCC 
GACCAGGAGG AGCTCTTTGG TCCTGTCAGC CTGGAGCAGG TCAAGTTCCC AGGTCCAGAG 
CATATCACCA ACGAGAAGCA GAAGCTGTTC ACCAGCAAGC TGTTGGATGT CATGGACAGG 
GGACTGATCC TGGAGGTCAG CGGACATGCC ATTTATGCCA TCAGGCTGTG CCAGTGCAAA 
GTGTACTGGT CAGGGCCATG TGCTCCCTCG CTTGCTGCTC CTAACCTGAT TGAGAGGCAG 
AAGAAGGTCA AGTTGTTTTG TCTGGAAACC TTCCTGAGTG AGCTCATTGC CCACCAGAAA 
GGACAGATAG AGAAGCAGCC GCCTTTTGAG ATCTACTTAT GCTTTGGGGA AGAGTGGCCA 
GATGGAAAGC CCCTGGAGAG GAAGCTCATC TTGGTCCAGG TCATCCCAGT GGTGGCTCGC 
ATGATCTATG AGATGTTTTC TGGTGATTTT ACCCGGTCCT TTGACAGTGG CAGCGTTCGC 
CTGCAGATCT CCACTCCAGA CATCAAAGAT AACATCGTTG CTCAGCTCAA GCAGCTGTAC 
CGCATCCTTC AAACCCAGGA GAGCTGGCAG CCCATGCAGC CTGCCCCCAG CATGCAGCTG 
CCACAGGCTC TGCCTGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058547.2
CDS	192..1595
Translation	MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQTQGSVINPGSTGSAPWDEKDNDVDEDEEEDELEQSQHHVPIQDTFPFLNINGSPMAPASVGNCSVGNCSPESVWPKTEPLEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLAAPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPAPSMQLPQALPAQ

Target ORF information:

RefSeq Version	NM_016851.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus interferon regulatory factor 6 (Irf6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016851.2

ORF Insert Sequence:

ATGGCCCTCC ACCCTCGAAG AGTCCGGCTG AAGCCCTGGC TGGTGGCCCA GGTGGACAGT 
GGCCTCTACC CTGGTCTCAT CTGGCTACAC AGAGATTCCA AACGCTTCCA GATCCCCTGG 
AAACATGCCA CGCGGCACAG CCCCCAACAA GAGGAAGAAA ACACCATTTT TAAGGCTTGG 
GCTGTGGAGA CCGGAAAGTA CCAGGAAGGG GTAGACGATC CTGACCCAGC TAAATGGAAG 
GCTCAGCTCC GCTGTGCTCT CAACAAAAGC AGGGAGTTCA ACTTGATGTA CGATGGCACC 
AAGGAAGTGC CCATGAATCC TGTGAAGATC TATCAAGTGT GTGACATCCC CCAGACCCAG 
GGCTCTGTCA TTAATCCAGG ATCCACAGGG TCTGCTCCTT GGGATGAGAA AGATAATGAT 
GTGGATGAAG ATGAGGAGGA GGATGAACTT GAGCAGTCAC AGCACCATGT CCCCATCCAG 
GACACCTTCC CCTTCCTGAA CATCAACGGT TCTCCCATGG CGCCAGCCAG CGTGGGCAAC 
TGCAGTGTGG GAAACTGCAG CCCCGAATCA GTGTGGCCCA AAACAGAACC TCTGGAGATG 
GAAGTACCCC AGGCACCCAT TCAACCCTTC TACAGTTCTC CAGAGCTATG GATCAGCTCT 
CTCCCCATGA CTGACTTGGA CATCAAATTT CAGTATCGTG GGAAGGAGTA TGGGCAAACT 
ATGACGGTGA GCAACCCCCA GGGCTGCCGG CTCTTCTATG GGGACCTGGG CCCCATGCCC 
GACCAGGAGG AGCTCTTTGG TCCTGTCAGC CTGGAGCAGG TCAAGTTCCC AGGTCCAGAG 
CATATCACCA ACGAGAAGCA GAAGCTGTTC ACCAGCAAGC TGTTGGATGT CATGGACAGG 
GGACTGATCC TGGAGGTCAG CGGACATGCC ATTTATGCCA TCAGGCTGTG CCAGTGCAAA 
GTGTACTGGT CAGGGCCATG TGCTCCCTCG CTTGCTGCTC CTAACCTGAT TGAGAGGCAG 
AAGAAGGTCA AGTTGTTTTG TCTGGAAACC TTCCTGAGTG AGCTCATTGC CCACCAGAAA 
GGACAGATAG AGAAGCAGCC GCCTTTTGAG ATCTACTTAT GCTTTGGGGA AGAGTGGCCA 
GATGGAAAGC CCCTGGAGAG GAAGCTCATC TTGGTCCAGG TCATCCCAGT GGTGGCTCGC 
ATGATCTATG AGATGTTTTC TGGTGATTTT ACCCGGTCCT TTGACAGTGG CAGCGTTCGC 
CTGCAGATCT CCACTCCAGA CATCAAAGAT AACATCGTTG CTCAGCTCAA GCAGCTGTAC 
CGCATCCTTC AAACCCAGGA GAGCTGGCAG CCCATGCAGC CTGCCCCCAG CATGCAGCTG 
CCACAGGCTC TGCCTGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irf6 ( XM_006497263.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006497326.1 Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu10782
Clone ID Related Accession (Same CDS sequence)	NM_016851.2 , XM_006497263.3 , XM_006497262.3 , XM_006497262.4 , XM_006497263.4
Accession Version	XM_006497263.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	interferon regulatory factor 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006497263.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCTCC ACCCTCGAAG AGTCCGGCTG AAGCCCTGGC TGGTGGCCCA GGTGGACAGT 
GGCCTCTACC CTGGTCTCAT CTGGCTACAC AGAGATTCCA AACGCTTCCA GATCCCCTGG 
AAACATGCCA CGCGGCACAG CCCCCAACAA GAGGAAGAAA ACACCATTTT TAAGGCTTGG 
GCTGTGGAGA CCGGAAAGTA CCAGGAAGGG GTAGACGATC CTGACCCAGC TAAATGGAAG 
GCTCAGCTCC GCTGTGCTCT CAACAAAAGC AGGGAGTTCA ACTTGATGTA CGATGGCACC 
AAGGAAGTGC CCATGAATCC TGTGAAGATC TATCAAGTGT GTGACATCCC CCAGACCCAG 
GGCTCTGTCA TTAATCCAGG ATCCACAGGG TCTGCTCCTT GGGATGAGAA AGATAATGAT 
GTGGATGAAG ATGAGGAGGA GGATGAACTT GAGCAGTCAC AGCACCATGT CCCCATCCAG 
GACACCTTCC CCTTCCTGAA CATCAACGGT TCTCCCATGG CGCCAGCCAG CGTGGGCAAC 
TGCAGTGTGG GAAACTGCAG CCCCGAATCA GTGTGGCCCA AAACAGAACC TCTGGAGATG 
GAAGTACCCC AGGCACCCAT TCAACCCTTC TACAGTTCTC CAGAGCTATG GATCAGCTCT 
CTCCCCATGA CTGACTTGGA CATCAAATTT CAGTATCGTG GGAAGGAGTA TGGGCAAACT 
ATGACGGTGA GCAACCCCCA GGGCTGCCGG CTCTTCTATG GGGACCTGGG CCCCATGCCC 
GACCAGGAGG AGCTCTTTGG TCCTGTCAGC CTGGAGCAGG TCAAGTTCCC AGGTCCAGAG 
CATATCACCA ACGAGAAGCA GAAGCTGTTC ACCAGCAAGC TGTTGGATGT CATGGACAGG 
GGACTGATCC TGGAGGTCAG CGGACATGCC ATTTATGCCA TCAGGCTGTG CCAGTGCAAA 
GTGTACTGGT CAGGGCCATG TGCTCCCTCG CTTGCTGCTC CTAACCTGAT TGAGAGGCAG 
AAGAAGGTCA AGTTGTTTTG TCTGGAAACC TTCCTGAGTG AGCTCATTGC CCACCAGAAA 
GGACAGATAG AGAAGCAGCC GCCTTTTGAG ATCTACTTAT GCTTTGGGGA AGAGTGGCCA 
GATGGAAAGC CCCTGGAGAG GAAGCTCATC TTGGTCCAGG TCATCCCAGT GGTGGCTCGC 
ATGATCTATG AGATGTTTTC TGGTGATTTT ACCCGGTCCT TTGACAGTGG CAGCGTTCGC 
CTGCAGATCT CCACTCCAGA CATCAAAGAT AACATCGTTG CTCAGCTCAA GCAGCTGTAC 
CGCATCCTTC AAACCCAGGA GAGCTGGCAG CCCATGCAGC CTGCCCCCAG CATGCAGCTG 
CCACAGGCTC TGCCTGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006497326.1
CDS	177..1580
Translation	MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQTQGSVINPGSTGSAPWDEKDNDVDEDEEEDELEQSQHHVPIQDTFPFLNINGSPMAPASVGNCSVGNCSPESVWPKTEPLEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLAAPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPAPSMQLPQALPAQ

Target ORF information:

RefSeq Version	XM_006497263.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006497263.3

ORF Insert Sequence:

ATGGCCCTCC ACCCTCGAAG AGTCCGGCTG AAGCCCTGGC TGGTGGCCCA GGTGGACAGT 
GGCCTCTACC CTGGTCTCAT CTGGCTACAC AGAGATTCCA AACGCTTCCA GATCCCCTGG 
AAACATGCCA CGCGGCACAG CCCCCAACAA GAGGAAGAAA ACACCATTTT TAAGGCTTGG 
GCTGTGGAGA CCGGAAAGTA CCAGGAAGGG GTAGACGATC CTGACCCAGC TAAATGGAAG 
GCTCAGCTCC GCTGTGCTCT CAACAAAAGC AGGGAGTTCA ACTTGATGTA CGATGGCACC 
AAGGAAGTGC CCATGAATCC TGTGAAGATC TATCAAGTGT GTGACATCCC CCAGACCCAG 
GGCTCTGTCA TTAATCCAGG ATCCACAGGG TCTGCTCCTT GGGATGAGAA AGATAATGAT 
GTGGATGAAG ATGAGGAGGA GGATGAACTT GAGCAGTCAC AGCACCATGT CCCCATCCAG 
GACACCTTCC CCTTCCTGAA CATCAACGGT TCTCCCATGG CGCCAGCCAG CGTGGGCAAC 
TGCAGTGTGG GAAACTGCAG CCCCGAATCA GTGTGGCCCA AAACAGAACC TCTGGAGATG 
GAAGTACCCC AGGCACCCAT TCAACCCTTC TACAGTTCTC CAGAGCTATG GATCAGCTCT 
CTCCCCATGA CTGACTTGGA CATCAAATTT CAGTATCGTG GGAAGGAGTA TGGGCAAACT 
ATGACGGTGA GCAACCCCCA GGGCTGCCGG CTCTTCTATG GGGACCTGGG CCCCATGCCC 
GACCAGGAGG AGCTCTTTGG TCCTGTCAGC CTGGAGCAGG TCAAGTTCCC AGGTCCAGAG 
CATATCACCA ACGAGAAGCA GAAGCTGTTC ACCAGCAAGC TGTTGGATGT CATGGACAGG 
GGACTGATCC TGGAGGTCAG CGGACATGCC ATTTATGCCA TCAGGCTGTG CCAGTGCAAA 
GTGTACTGGT CAGGGCCATG TGCTCCCTCG CTTGCTGCTC CTAACCTGAT TGAGAGGCAG 
AAGAAGGTCA AGTTGTTTTG TCTGGAAACC TTCCTGAGTG AGCTCATTGC CCACCAGAAA 
GGACAGATAG AGAAGCAGCC GCCTTTTGAG ATCTACTTAT GCTTTGGGGA AGAGTGGCCA 
GATGGAAAGC CCCTGGAGAG GAAGCTCATC TTGGTCCAGG TCATCCCAGT GGTGGCTCGC 
ATGATCTATG AGATGTTTTC TGGTGATTTT ACCCGGTCCT TTGACAGTGG CAGCGTTCGC 
CTGCAGATCT CCACTCCAGA CATCAAAGAT AACATCGTTG CTCAGCTCAA GCAGCTGTAC 
CGCATCCTTC AAACCCAGGA GAGCTGGCAG CCCATGCAGC CTGCCCCCAG CATGCAGCTG 
CCACAGGCTC TGCCTGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irf6 ( XM_006497262.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006497325.1 Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu10782
Clone ID Related Accession (Same CDS sequence)	NM_016851.2 , XM_006497263.3 , XM_006497262.3 , XM_006497262.4 , XM_006497263.4
Accession Version	XM_006497262.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	interferon regulatory factor 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006497262.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCTCC ACCCTCGAAG AGTCCGGCTG AAGCCCTGGC TGGTGGCCCA GGTGGACAGT 
GGCCTCTACC CTGGTCTCAT CTGGCTACAC AGAGATTCCA AACGCTTCCA GATCCCCTGG 
AAACATGCCA CGCGGCACAG CCCCCAACAA GAGGAAGAAA ACACCATTTT TAAGGCTTGG 
GCTGTGGAGA CCGGAAAGTA CCAGGAAGGG GTAGACGATC CTGACCCAGC TAAATGGAAG 
GCTCAGCTCC GCTGTGCTCT CAACAAAAGC AGGGAGTTCA ACTTGATGTA CGATGGCACC 
AAGGAAGTGC CCATGAATCC TGTGAAGATC TATCAAGTGT GTGACATCCC CCAGACCCAG 
GGCTCTGTCA TTAATCCAGG ATCCACAGGG TCTGCTCCTT GGGATGAGAA AGATAATGAT 
GTGGATGAAG ATGAGGAGGA GGATGAACTT GAGCAGTCAC AGCACCATGT CCCCATCCAG 
GACACCTTCC CCTTCCTGAA CATCAACGGT TCTCCCATGG CGCCAGCCAG CGTGGGCAAC 
TGCAGTGTGG GAAACTGCAG CCCCGAATCA GTGTGGCCCA AAACAGAACC TCTGGAGATG 
GAAGTACCCC AGGCACCCAT TCAACCCTTC TACAGTTCTC CAGAGCTATG GATCAGCTCT 
CTCCCCATGA CTGACTTGGA CATCAAATTT CAGTATCGTG GGAAGGAGTA TGGGCAAACT 
ATGACGGTGA GCAACCCCCA GGGCTGCCGG CTCTTCTATG GGGACCTGGG CCCCATGCCC 
GACCAGGAGG AGCTCTTTGG TCCTGTCAGC CTGGAGCAGG TCAAGTTCCC AGGTCCAGAG 
CATATCACCA ACGAGAAGCA GAAGCTGTTC ACCAGCAAGC TGTTGGATGT CATGGACAGG 
GGACTGATCC TGGAGGTCAG CGGACATGCC ATTTATGCCA TCAGGCTGTG CCAGTGCAAA 
GTGTACTGGT CAGGGCCATG TGCTCCCTCG CTTGCTGCTC CTAACCTGAT TGAGAGGCAG 
AAGAAGGTCA AGTTGTTTTG TCTGGAAACC TTCCTGAGTG AGCTCATTGC CCACCAGAAA 
GGACAGATAG AGAAGCAGCC GCCTTTTGAG ATCTACTTAT GCTTTGGGGA AGAGTGGCCA 
GATGGAAAGC CCCTGGAGAG GAAGCTCATC TTGGTCCAGG TCATCCCAGT GGTGGCTCGC 
ATGATCTATG AGATGTTTTC TGGTGATTTT ACCCGGTCCT TTGACAGTGG CAGCGTTCGC 
CTGCAGATCT CCACTCCAGA CATCAAAGAT AACATCGTTG CTCAGCTCAA GCAGCTGTAC 
CGCATCCTTC AAACCCAGGA GAGCTGGCAG CCCATGCAGC CTGCCCCCAG CATGCAGCTG 
CCACAGGCTC TGCCTGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006497325.1
CDS	295..1698
Translation	MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQTQGSVINPGSTGSAPWDEKDNDVDEDEEEDELEQSQHHVPIQDTFPFLNINGSPMAPASVGNCSVGNCSPESVWPKTEPLEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLAAPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPAPSMQLPQALPAQ

Target ORF information:

RefSeq Version	XM_006497262.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006497262.3

ORF Insert Sequence:

ATGGCCCTCC ACCCTCGAAG AGTCCGGCTG AAGCCCTGGC TGGTGGCCCA GGTGGACAGT 
GGCCTCTACC CTGGTCTCAT CTGGCTACAC AGAGATTCCA AACGCTTCCA GATCCCCTGG 
AAACATGCCA CGCGGCACAG CCCCCAACAA GAGGAAGAAA ACACCATTTT TAAGGCTTGG 
GCTGTGGAGA CCGGAAAGTA CCAGGAAGGG GTAGACGATC CTGACCCAGC TAAATGGAAG 
GCTCAGCTCC GCTGTGCTCT CAACAAAAGC AGGGAGTTCA ACTTGATGTA CGATGGCACC 
AAGGAAGTGC CCATGAATCC TGTGAAGATC TATCAAGTGT GTGACATCCC CCAGACCCAG 
GGCTCTGTCA TTAATCCAGG ATCCACAGGG TCTGCTCCTT GGGATGAGAA AGATAATGAT 
GTGGATGAAG ATGAGGAGGA GGATGAACTT GAGCAGTCAC AGCACCATGT CCCCATCCAG 
GACACCTTCC CCTTCCTGAA CATCAACGGT TCTCCCATGG CGCCAGCCAG CGTGGGCAAC 
TGCAGTGTGG GAAACTGCAG CCCCGAATCA GTGTGGCCCA AAACAGAACC TCTGGAGATG 
GAAGTACCCC AGGCACCCAT TCAACCCTTC TACAGTTCTC CAGAGCTATG GATCAGCTCT 
CTCCCCATGA CTGACTTGGA CATCAAATTT CAGTATCGTG GGAAGGAGTA TGGGCAAACT 
ATGACGGTGA GCAACCCCCA GGGCTGCCGG CTCTTCTATG GGGACCTGGG CCCCATGCCC 
GACCAGGAGG AGCTCTTTGG TCCTGTCAGC CTGGAGCAGG TCAAGTTCCC AGGTCCAGAG 
CATATCACCA ACGAGAAGCA GAAGCTGTTC ACCAGCAAGC TGTTGGATGT CATGGACAGG 
GGACTGATCC TGGAGGTCAG CGGACATGCC ATTTATGCCA TCAGGCTGTG CCAGTGCAAA 
GTGTACTGGT CAGGGCCATG TGCTCCCTCG CTTGCTGCTC CTAACCTGAT TGAGAGGCAG 
AAGAAGGTCA AGTTGTTTTG TCTGGAAACC TTCCTGAGTG AGCTCATTGC CCACCAGAAA 
GGACAGATAG AGAAGCAGCC GCCTTTTGAG ATCTACTTAT GCTTTGGGGA AGAGTGGCCA 
GATGGAAAGC CCCTGGAGAG GAAGCTCATC TTGGTCCAGG TCATCCCAGT GGTGGCTCGC 
ATGATCTATG AGATGTTTTC TGGTGATTTT ACCCGGTCCT TTGACAGTGG CAGCGTTCGC 
CTGCAGATCT CCACTCCAGA CATCAAAGAT AACATCGTTG CTCAGCTCAA GCAGCTGTAC 
CGCATCCTTC AAACCCAGGA GAGCTGGCAG CCCATGCAGC CTGCCCCCAG CATGCAGCTG 
CCACAGGCTC TGCCTGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irf6 ( XM_006497262.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006497325.1 Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X1, mRNA.

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CloneID	OMu10782
Clone ID Related Accession (Same CDS sequence)	NM_016851.2 , XM_006497263.3 , XM_006497262.3 , XM_006497262.4 , XM_006497263.4
Accession Version	XM_006497262.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	interferon regulatory factor 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006497262.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCTCC ACCCTCGAAG AGTCCGGCTG AAGCCCTGGC TGGTGGCCCA GGTGGACAGT 
GGCCTCTACC CTGGTCTCAT CTGGCTACAC AGAGATTCCA AACGCTTCCA GATCCCCTGG 
AAACATGCCA CGCGGCACAG CCCCCAACAA GAGGAAGAAA ACACCATTTT TAAGGCTTGG 
GCTGTGGAGA CCGGAAAGTA CCAGGAAGGG GTAGACGATC CTGACCCAGC TAAATGGAAG 
GCTCAGCTCC GCTGTGCTCT CAACAAAAGC AGGGAGTTCA ACTTGATGTA CGATGGCACC 
AAGGAAGTGC CCATGAATCC TGTGAAGATC TATCAAGTGT GTGACATCCC CCAGACCCAG 
GGCTCTGTCA TTAATCCAGG ATCCACAGGG TCTGCTCCTT GGGATGAGAA AGATAATGAT 
GTGGATGAAG ATGAGGAGGA GGATGAACTT GAGCAGTCAC AGCACCATGT CCCCATCCAG 
GACACCTTCC CCTTCCTGAA CATCAACGGT TCTCCCATGG CGCCAGCCAG CGTGGGCAAC 
TGCAGTGTGG GAAACTGCAG CCCCGAATCA GTGTGGCCCA AAACAGAACC TCTGGAGATG 
GAAGTACCCC AGGCACCCAT TCAACCCTTC TACAGTTCTC CAGAGCTATG GATCAGCTCT 
CTCCCCATGA CTGACTTGGA CATCAAATTT CAGTATCGTG GGAAGGAGTA TGGGCAAACT 
ATGACGGTGA GCAACCCCCA GGGCTGCCGG CTCTTCTATG GGGACCTGGG CCCCATGCCC 
GACCAGGAGG AGCTCTTTGG TCCTGTCAGC CTGGAGCAGG TCAAGTTCCC AGGTCCAGAG 
CATATCACCA ACGAGAAGCA GAAGCTGTTC ACCAGCAAGC TGTTGGATGT CATGGACAGG 
GGACTGATCC TGGAGGTCAG CGGACATGCC ATTTATGCCA TCAGGCTGTG CCAGTGCAAA 
GTGTACTGGT CAGGGCCATG TGCTCCCTCG CTTGCTGCTC CTAACCTGAT TGAGAGGCAG 
AAGAAGGTCA AGTTGTTTTG TCTGGAAACC TTCCTGAGTG AGCTCATTGC CCACCAGAAA 
GGACAGATAG AGAAGCAGCC GCCTTTTGAG ATCTACTTAT GCTTTGGGGA AGAGTGGCCA 
GATGGAAAGC CCCTGGAGAG GAAGCTCATC TTGGTCCAGG TCATCCCAGT GGTGGCTCGC 
ATGATCTATG AGATGTTTTC TGGTGATTTT ACCCGGTCCT TTGACAGTGG CAGCGTTCGC 
CTGCAGATCT CCACTCCAGA CATCAAAGAT AACATCGTTG CTCAGCTCAA GCAGCTGTAC 
CGCATCCTTC AAACCCAGGA GAGCTGGCAG CCCATGCAGC CTGCCCCCAG CATGCAGCTG 
CCACAGGCTC TGCCTGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006497325.1
CDS	86..1489
Translation	MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQTQGSVINPGSTGSAPWDEKDNDVDEDEEEDELEQSQHHVPIQDTFPFLNINGSPMAPASVGNCSVGNCSPESVWPKTEPLEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLAAPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPAPSMQLPQALPAQ

Target ORF information:

RefSeq Version	XM_006497262.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006497262.4

ORF Insert Sequence:

ATGGCCCTCC ACCCTCGAAG AGTCCGGCTG AAGCCCTGGC TGGTGGCCCA GGTGGACAGT 
GGCCTCTACC CTGGTCTCAT CTGGCTACAC AGAGATTCCA AACGCTTCCA GATCCCCTGG 
AAACATGCCA CGCGGCACAG CCCCCAACAA GAGGAAGAAA ACACCATTTT TAAGGCTTGG 
GCTGTGGAGA CCGGAAAGTA CCAGGAAGGG GTAGACGATC CTGACCCAGC TAAATGGAAG 
GCTCAGCTCC GCTGTGCTCT CAACAAAAGC AGGGAGTTCA ACTTGATGTA CGATGGCACC 
AAGGAAGTGC CCATGAATCC TGTGAAGATC TATCAAGTGT GTGACATCCC CCAGACCCAG 
GGCTCTGTCA TTAATCCAGG ATCCACAGGG TCTGCTCCTT GGGATGAGAA AGATAATGAT 
GTGGATGAAG ATGAGGAGGA GGATGAACTT GAGCAGTCAC AGCACCATGT CCCCATCCAG 
GACACCTTCC CCTTCCTGAA CATCAACGGT TCTCCCATGG CGCCAGCCAG CGTGGGCAAC 
TGCAGTGTGG GAAACTGCAG CCCCGAATCA GTGTGGCCCA AAACAGAACC TCTGGAGATG 
GAAGTACCCC AGGCACCCAT TCAACCCTTC TACAGTTCTC CAGAGCTATG GATCAGCTCT 
CTCCCCATGA CTGACTTGGA CATCAAATTT CAGTATCGTG GGAAGGAGTA TGGGCAAACT 
ATGACGGTGA GCAACCCCCA GGGCTGCCGG CTCTTCTATG GGGACCTGGG CCCCATGCCC 
GACCAGGAGG AGCTCTTTGG TCCTGTCAGC CTGGAGCAGG TCAAGTTCCC AGGTCCAGAG 
CATATCACCA ACGAGAAGCA GAAGCTGTTC ACCAGCAAGC TGTTGGATGT CATGGACAGG 
GGACTGATCC TGGAGGTCAG CGGACATGCC ATTTATGCCA TCAGGCTGTG CCAGTGCAAA 
GTGTACTGGT CAGGGCCATG TGCTCCCTCG CTTGCTGCTC CTAACCTGAT TGAGAGGCAG 
AAGAAGGTCA AGTTGTTTTG TCTGGAAACC TTCCTGAGTG AGCTCATTGC CCACCAGAAA 
GGACAGATAG AGAAGCAGCC GCCTTTTGAG ATCTACTTAT GCTTTGGGGA AGAGTGGCCA 
GATGGAAAGC CCCTGGAGAG GAAGCTCATC TTGGTCCAGG TCATCCCAGT GGTGGCTCGC 
ATGATCTATG AGATGTTTTC TGGTGATTTT ACCCGGTCCT TTGACAGTGG CAGCGTTCGC 
CTGCAGATCT CCACTCCAGA CATCAAAGAT AACATCGTTG CTCAGCTCAA GCAGCTGTAC 
CGCATCCTTC AAACCCAGGA GAGCTGGCAG CCCATGCAGC CTGCCCCCAG CATGCAGCTG 
CCACAGGCTC TGCCTGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irf6 ( XM_006497263.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006497326.1 Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X2, mRNA.

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CloneID	OMu10782
Clone ID Related Accession (Same CDS sequence)	NM_016851.2 , XM_006497263.3 , XM_006497262.3 , XM_006497262.4 , XM_006497263.4
Accession Version	XM_006497263.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	interferon regulatory factor 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006497263.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCTCC ACCCTCGAAG AGTCCGGCTG AAGCCCTGGC TGGTGGCCCA GGTGGACAGT 
GGCCTCTACC CTGGTCTCAT CTGGCTACAC AGAGATTCCA AACGCTTCCA GATCCCCTGG 
AAACATGCCA CGCGGCACAG CCCCCAACAA GAGGAAGAAA ACACCATTTT TAAGGCTTGG 
GCTGTGGAGA CCGGAAAGTA CCAGGAAGGG GTAGACGATC CTGACCCAGC TAAATGGAAG 
GCTCAGCTCC GCTGTGCTCT CAACAAAAGC AGGGAGTTCA ACTTGATGTA CGATGGCACC 
AAGGAAGTGC CCATGAATCC TGTGAAGATC TATCAAGTGT GTGACATCCC CCAGACCCAG 
GGCTCTGTCA TTAATCCAGG ATCCACAGGG TCTGCTCCTT GGGATGAGAA AGATAATGAT 
GTGGATGAAG ATGAGGAGGA GGATGAACTT GAGCAGTCAC AGCACCATGT CCCCATCCAG 
GACACCTTCC CCTTCCTGAA CATCAACGGT TCTCCCATGG CGCCAGCCAG CGTGGGCAAC 
TGCAGTGTGG GAAACTGCAG CCCCGAATCA GTGTGGCCCA AAACAGAACC TCTGGAGATG 
GAAGTACCCC AGGCACCCAT TCAACCCTTC TACAGTTCTC CAGAGCTATG GATCAGCTCT 
CTCCCCATGA CTGACTTGGA CATCAAATTT CAGTATCGTG GGAAGGAGTA TGGGCAAACT 
ATGACGGTGA GCAACCCCCA GGGCTGCCGG CTCTTCTATG GGGACCTGGG CCCCATGCCC 
GACCAGGAGG AGCTCTTTGG TCCTGTCAGC CTGGAGCAGG TCAAGTTCCC AGGTCCAGAG 
CATATCACCA ACGAGAAGCA GAAGCTGTTC ACCAGCAAGC TGTTGGATGT CATGGACAGG 
GGACTGATCC TGGAGGTCAG CGGACATGCC ATTTATGCCA TCAGGCTGTG CCAGTGCAAA 
GTGTACTGGT CAGGGCCATG TGCTCCCTCG CTTGCTGCTC CTAACCTGAT TGAGAGGCAG 
AAGAAGGTCA AGTTGTTTTG TCTGGAAACC TTCCTGAGTG AGCTCATTGC CCACCAGAAA 
GGACAGATAG AGAAGCAGCC GCCTTTTGAG ATCTACTTAT GCTTTGGGGA AGAGTGGCCA 
GATGGAAAGC CCCTGGAGAG GAAGCTCATC TTGGTCCAGG TCATCCCAGT GGTGGCTCGC 
ATGATCTATG AGATGTTTTC TGGTGATTTT ACCCGGTCCT TTGACAGTGG CAGCGTTCGC 
CTGCAGATCT CCACTCCAGA CATCAAAGAT AACATCGTTG CTCAGCTCAA GCAGCTGTAC 
CGCATCCTTC AAACCCAGGA GAGCTGGCAG CCCATGCAGC CTGCCCCCAG CATGCAGCTG 
CCACAGGCTC TGCCTGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006497326.1
CDS	97..1500
Translation	MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQTQGSVINPGSTGSAPWDEKDNDVDEDEEEDELEQSQHHVPIQDTFPFLNINGSPMAPASVGNCSVGNCSPESVWPKTEPLEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLAAPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPAPSMQLPQALPAQ

Target ORF information:

RefSeq Version	XM_006497263.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus interferon regulatory factor 6 (Irf6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006497263.4

ORF Insert Sequence:

ATGGCCCTCC ACCCTCGAAG AGTCCGGCTG AAGCCCTGGC TGGTGGCCCA GGTGGACAGT 
GGCCTCTACC CTGGTCTCAT CTGGCTACAC AGAGATTCCA AACGCTTCCA GATCCCCTGG 
AAACATGCCA CGCGGCACAG CCCCCAACAA GAGGAAGAAA ACACCATTTT TAAGGCTTGG 
GCTGTGGAGA CCGGAAAGTA CCAGGAAGGG GTAGACGATC CTGACCCAGC TAAATGGAAG 
GCTCAGCTCC GCTGTGCTCT CAACAAAAGC AGGGAGTTCA ACTTGATGTA CGATGGCACC 
AAGGAAGTGC CCATGAATCC TGTGAAGATC TATCAAGTGT GTGACATCCC CCAGACCCAG 
GGCTCTGTCA TTAATCCAGG ATCCACAGGG TCTGCTCCTT GGGATGAGAA AGATAATGAT 
GTGGATGAAG ATGAGGAGGA GGATGAACTT GAGCAGTCAC AGCACCATGT CCCCATCCAG 
GACACCTTCC CCTTCCTGAA CATCAACGGT TCTCCCATGG CGCCAGCCAG CGTGGGCAAC 
TGCAGTGTGG GAAACTGCAG CCCCGAATCA GTGTGGCCCA AAACAGAACC TCTGGAGATG 
GAAGTACCCC AGGCACCCAT TCAACCCTTC TACAGTTCTC CAGAGCTATG GATCAGCTCT 
CTCCCCATGA CTGACTTGGA CATCAAATTT CAGTATCGTG GGAAGGAGTA TGGGCAAACT 
ATGACGGTGA GCAACCCCCA GGGCTGCCGG CTCTTCTATG GGGACCTGGG CCCCATGCCC 
GACCAGGAGG AGCTCTTTGG TCCTGTCAGC CTGGAGCAGG TCAAGTTCCC AGGTCCAGAG 
CATATCACCA ACGAGAAGCA GAAGCTGTTC ACCAGCAAGC TGTTGGATGT CATGGACAGG 
GGACTGATCC TGGAGGTCAG CGGACATGCC ATTTATGCCA TCAGGCTGTG CCAGTGCAAA 
GTGTACTGGT CAGGGCCATG TGCTCCCTCG CTTGCTGCTC CTAACCTGAT TGAGAGGCAG 
AAGAAGGTCA AGTTGTTTTG TCTGGAAACC TTCCTGAGTG AGCTCATTGC CCACCAGAAA 
GGACAGATAG AGAAGCAGCC GCCTTTTGAG ATCTACTTAT GCTTTGGGGA AGAGTGGCCA 
GATGGAAAGC CCCTGGAGAG GAAGCTCATC TTGGTCCAGG TCATCCCAGT GGTGGCTCGC 
ATGATCTATG AGATGTTTTC TGGTGATTTT ACCCGGTCCT TTGACAGTGG CAGCGTTCGC 
CTGCAGATCT CCACTCCAGA CATCAAAGAT AACATCGTTG CTCAGCTCAA GCAGCTGTAC 
CGCATCCTTC AAACCCAGGA GAGCTGGCAG CCCATGCAGC CTGCCCCCAG CATGCAGCTG 
CCACAGGCTC TGCCTGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.
Nature574(7777)249-253(2019 10)
Oberbeck N,Pham VC,Webster JD,Reja R,Huang CS,Zhang Y,Roose-Girma M,Warming S,Li Q,Birnberg A,Wong W,Sandoval W,Kőműves LG,Yu K,Dugger DL,Maltzman A,Newton K,Dixit VM

The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation.
Human molecular genetics28(10)1726-1737(2019 05)
Kousa YA,Zhu H,Fakhouri WD,Lei Y,Kinoshita A,Roushangar RR,Patel NK,Agopian AJ,Yang W,Leslie EJ,Busch TD,Mansour TA,Li X,Smith AL,Li EB,Sharma DB,Williams TJ,Chai Y,Amendt BA,Liao EC,Mitchell LE,Bassuk AG,Gregory S,Ashley-Koch A,Shaw GM,Finnell RH,Schutte BC

A cleft lip and palate gene, Irf6, is involved in osteoblast differentiation of craniofacial bone.
Developmental dynamics : an official publication of the American Association of Anatomists248(3)221-232(2019 03)
Thompson J,Mendoza F,Tan E,Bertol JW,Gaggar AS,Jun G,Biguetti C,Fakhouri WD

IRF6 and AP2A Interaction Regulates Epidermal Development.
The Journal of investigative dermatology138(12)2578-2588(2018 12)
Kousa YA,Fuller E,Schutte BC

Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion.
Developmental biology441(1)191-203(2018 09)
Li J,Yuan Y,He J,Feng J,Han X,Jing J,Ho TV,Xu J,Chai Y

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Irf6 cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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