Map2k7 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Map2k7
Entrez Gene ID	26400
Full Name	mitogen-activated protein kinase kinase 7
Synonyms	5930412N11Rik,JNKK 2,Jnkk2,MAPKK 7,MEK 7,Mapkk7,Mek7,Mkk7,Prkmk7,sek2
General protein information	Preferred Names mitogen-activated protein kinase kinase 7 Names dual specificity mitogen-activated protein kinase kinase 7 JNK kinase 2 JNK-activating kinase 2 MAP kinase kinase 7 MAPK/ERK kinase 7 c-Jun N-terminal kinase kinase 2 map2k7 protein kinase, mitogen activated, kinase 7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 A1.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001042557.2	NP_001036022.1	dual specificity mitogen-activated protein kinase kinase 7 isoform 1
NM_001291777.1	NP_001278706.1	dual specificity mitogen-activated protein kinase kinase 7 isoform 4
NM_011944.3	NP_036074.2	dual specificity mitogen-activated protein kinase kinase 7 isoform 2
NM_001164172.1	NP_001157644.1	dual specificity mitogen-activated protein kinase kinase 7 isoform 3
NM_001291778.1	NP_001278707.1	dual specificity mitogen-activated protein kinase kinase 7 isoform 5
NM_001291783.1	NP_001278712.1	dual specificity mitogen-activated protein kinase kinase 7 isoform 6

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	map2k7	NP_001177235.1
Homo sapiens (human)	MAP2K7	NP_660186.1
Canis lupus familiaris (dog)	MAP2K7	XP_542122.2
Caenorhabditis elegans (roundworm)	mek-1	NP_001024771.1
Pan troglodytes (chimpanzee)	MAP2K7	XP_003316108.1
Bos taurus (cattle)	MAP2K7	XP_002688882.2
Rattus norvegicus (Norway rat)	Map2k7	NP_001020596.1
Mus musculus (house mouse)	Map2k7	NP_001036022.1
Drosophila melanogaster (fruit fly)	hep	NP_511142.2
Xenopus tropicalis (tropical clawed frog)	map2k7	NP_001027523.1

Gene Ontology
Bibliography

Related articles in PubMed

Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia.
Hwang SH, Somatilaka BN, Badgandi H, Palicharla VR, Walker R, Shelton JM, Qian F, Mukhopadhyay S
Current biology : CB29(5)790-802.e5(2019 03)

Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death.
Syc-Mazurek SB, Rausch RL, Fernandes KA, Wilson MP, Libby RT
Cell death & disease9(11)1095(2018 10)

DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.
Lao Y, Yang K, Wang Z, Sun X, Zou Q, Yu X, Cheng J, Tong X, Yeh ETH, Yang J, Yi J
The Journal of biological chemistry293(11)3965-3980(2018 03)

A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress.
Kant S, Standen CL, Morel C, Jung DY, Kim JK, Swat W, Flavell RA, Davis RJ
Cell reports20(12)2775-2783(2017 Sep)

Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.
Yamasaki T, Deki-Arima N, Kaneko A, Miyamura N, Iwatsuki M, Matsuoka M, Fujimori-Tonou N, Okamoto-Uchida Y, Hirayama J, Marth JD, Yamanashi Y, Kawasaki H, Yamanaka K, Penninger JM, Shibata S, Nishina H
Scientific reports7(1)7348(2017 08)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Map2k7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Map2k7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu00924	NM_001042557.2 Latest version!	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu18494	NM_001291777.1 Latest version!	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu18495	NM_001291778.1 Latest version!	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu18496	NM_001164172.1 Latest version!	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu18497	NM_011944.3 Latest version!	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu18498	NM_001291783.1 Latest version!	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Map2k7 ( NM_001042557.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001036022.1 Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu00924
Clone ID Related Accession (Same CDS sequence)	NM_001042557.2
Accession Version	NM_001042557.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1407bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	dual specificity mitogen-activated protein kinase kinase 7 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB842920.1 and AB005654.1. On Aug 13, 2009 this sequence version replaced NM_001042557.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF060947.1, AB005654.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGT CCTCCCTGGA GCAGAAGCTG TCCCGCCTGG AAGCCAAGCT GAAGCAGGAG 
AACCGTGAGG CCCGCAGGAG GATCGACCTC AACTTGGATA TCAGCCCACA GCGGCCCAGG 
CCCATTATTG TGATCACTCT AAGCCCTGCT CCTGCCCCGT CCCAGCGAGC AGCCCTGCAA 
CTCCCACTGG CCAACGATGG GGGCAGCCGC TCACCATCCT CAGAGAGCTC CCCACAGCAC 
CCTACACCCC CCACCCGGCC CCGCCACATG CTGGGGCTCC CATCAACCTT GTTCACACCG 
CGCAGTATGG AGAGCATCGA GATTGACCAG AAGCTGCAGG AGATCATGAA GCAGACAGGG 
TACCTGACTA TCGGGGGCCA GCGTTATCAG GCAGAAATCA ATGACTTGGA GAACTTGGGT 
GAGATGGGCA GTGGTACCTG TGGTCAGGTG TGGAAGATGC GGTTCCGGAA GACAGGCCAC 
ATCATTGCTG TTAAGCAAAT GCGGCGCTCT GGGAACAAGG AAGAGAATAA GCGCATTTTG 
ATGGACCTGG ATGTAGTACT CAAGAGCCAT GACTGCCCTT ACATCGTTCA GTGCTTTGGC 
ACCTTCATCA CCAACACAGA CGTCTTTATT GCCATGGAGC TCATGGGCAC ATGTGCAGAG 
AAGCTGAAGA AACGAATGCA GGGCCCCATT CCAGAGCGAA TCCTGGGCAA GATGACTGTG 
GCGATTGTGA AAGCACTGTA CTATCTGAAG GAGAAGCATG GCGTCATCCA TCGCGATGTC 
AAACCCTCCA ACATCCTGCT AGATGAGCGG GGCCAGATCA AGCTCTGTGA CTTTGGCATC 
AGTGGCCGCC TTGTTGACTC CAAAGCCAAA ACACGGAGTG CTGGCTGTGC TGCCTATATG 
GCTCCCGAGC GCATCGACCC TCCAGATCCC ACCAAGCCTG ACTATGACAT CCGAGCTGAT 
GTGTGGAGCC TGGGCATCTC ACTGGTGGAG CTGGCAACAG GACAGTTCCC CTATAAGAAC 
TGCAAGACGG ACTTTGAGGT CCTCACCAAA GTCCTACAGG AAGAGCCCCC ACTCCTGCCT 
GGTCACATGG GCTTCTCAGG GGACTTCCAG TCATTTGTCA AAGACTGCCT TACTAAAGAT 
CACAGGAAGA GACCAAAGTA TAATAAGCTA CTTGAACACA GCTTCATCAA GCACTATGAG 
ATACTCGAGG TGGATGTCGC GTCCTGGTTT AAGGATGTCA TGGCGAAGAC CGAGTCCCCA 
AGGACTAGTG GAGTCCTGAG TCAGCACCAT CTGCCCTTCT TCAGTGGGAG TCTGGAGGAG 
TCTCCCACTT CCCCACCTTC TCCCAAGTCC TTCCCTCTGT CACCAGCCAT CCCTCAGGCC 
CAGGCAGAGT GGGTCTCGGG CAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001036022.1
CDS	171..1577
Translation	MAASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPRPIIVITLSPAPAPSQRAALQLPLANDGGSRSPSSESSPQHPTPPTRPRHMLGLPSTLFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKHYEILEVDVASWFKDVMAKTESPRTSGVLSQHHLPFFSGSLEESPTSPPSPKSFPLSPAIPQAQAEWVSGR

Target ORF information:

RefSeq Version	NM_001042557.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042557.2

ORF Insert Sequence:

ATGGCGGCGT CCTCCCTGGA GCAGAAGCTG TCCCGCCTGG AAGCCAAGCT GAAGCAGGAG 
AACCGTGAGG CCCGCAGGAG GATCGACCTC AACTTGGATA TCAGCCCACA GCGGCCCAGG 
CCCATTATTG TGATCACTCT AAGCCCTGCT CCTGCCCCGT CCCAGCGAGC AGCCCTGCAA 
CTCCCACTGG CCAACGATGG GGGCAGCCGC TCACCATCCT CAGAGAGCTC CCCACAGCAC 
CCTACACCCC CCACCCGGCC CCGCCACATG CTGGGGCTCC CATCAACCTT GTTCACACCG 
CGCAGTATGG AGAGCATCGA GATTGACCAG AAGCTGCAGG AGATCATGAA GCAGACAGGG 
TACCTGACTA TCGGGGGCCA GCGTTATCAG GCAGAAATCA ATGACTTGGA GAACTTGGGT 
GAGATGGGCA GTGGTACCTG TGGTCAGGTG TGGAAGATGC GGTTCCGGAA GACAGGCCAC 
ATCATTGCTG TTAAGCAAAT GCGGCGCTCT GGGAACAAGG AAGAGAATAA GCGCATTTTG 
ATGGACCTGG ATGTAGTACT CAAGAGCCAT GACTGCCCTT ACATCGTTCA GTGCTTTGGC 
ACCTTCATCA CCAACACAGA CGTCTTTATT GCCATGGAGC TCATGGGCAC ATGTGCAGAG 
AAGCTGAAGA AACGAATGCA GGGCCCCATT CCAGAGCGAA TCCTGGGCAA GATGACTGTG 
GCGATTGTGA AAGCACTGTA CTATCTGAAG GAGAAGCATG GCGTCATCCA TCGCGATGTC 
AAACCCTCCA ACATCCTGCT AGATGAGCGG GGCCAGATCA AGCTCTGTGA CTTTGGCATC 
AGTGGCCGCC TTGTTGACTC CAAAGCCAAA ACACGGAGTG CTGGCTGTGC TGCCTATATG 
GCTCCCGAGC GCATCGACCC TCCAGATCCC ACCAAGCCTG ACTATGACAT CCGAGCTGAT 
GTGTGGAGCC TGGGCATCTC ACTGGTGGAG CTGGCAACAG GACAGTTCCC CTATAAGAAC 
TGCAAGACGG ACTTTGAGGT CCTCACCAAA GTCCTACAGG AAGAGCCCCC ACTCCTGCCT 
GGTCACATGG GCTTCTCAGG GGACTTCCAG TCATTTGTCA AAGACTGCCT TACTAAAGAT 
CACAGGAAGA GACCAAAGTA TAATAAGCTA CTTGAACACA GCTTCATCAA GCACTATGAG 
ATACTCGAGG TGGATGTCGC GTCCTGGTTT AAGGATGTCA TGGCGAAGAC CGAGTCCCCA 
AGGACTAGTG GAGTCCTGAG TCAGCACCAT CTGCCCTTCT TCAGTGGGAG TCTGGAGGAG 
TCTCCCACTT CCCCACCTTC TCCCAAGTCC TTCCCTCTGT CACCAGCCAT CCCTCAGGCC 
CAGGCAGAGT GGGTCTCGGG CAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Map2k7 ( NM_001291777.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001278706.1 Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu18494
Clone ID Related Accession (Same CDS sequence)	NM_001291777.1
Accession Version	NM_001291777.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1359bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	dual specificity mitogen-activated protein kinase kinase 7 isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB842920.1, AK165184.1 and AB005654.1. Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF060945.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGT CCTCCCTGGA GCAGAAGCTG TCCCGCCTGG AAGCCAAGCT GAAGCAGGAG 
AACCGTGAGG CCCGCAGGAG GATCGACCTC AACTTGGATA TCAGCCCACA GCGGCCCAGG 
CCCACCCTGC AACTCCCACT GGCCAACGAT GGGGGCAGCC GCTCACCATC CTCAGAGAGC 
TCCCCACAGC ACCCTACACC CCCCACCCGG CCCCGCCACA TGCTGGGGCT CCCATCAACC 
TTGTTCACAC CGCGCAGTAT GGAGAGCATC GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACAG GGTACCTGAC TATCGGGGGC CAGCGTTATC AGGCAGAAAT CAATGACTTG 
GAGAACTTGG GTGAGATGGG CAGTGGTACC TGTGGTCAGG TGTGGAAGAT GCGGTTCCGG 
AAGACAGGCC ACATCATTGC TGTTAAGCAA ATGCGGCGCT CTGGGAACAA GGAAGAGAAT 
AAGCGCATTT TGATGGACCT GGATGTAGTA CTCAAGAGCC ATGACTGCCC TTACATCGTT 
CAGTGCTTTG GCACCTTCAT CACCAACACA GACGTCTTTA TTGCCATGGA GCTCATGGGC 
ACATGTGCAG AGAAGCTGAA GAAACGAATG CAGGGCCCCA TTCCAGAGCG AATCCTGGGC 
AAGATGACTG TGGCGATTGT GAAAGCACTG TACTATCTGA AGGAGAAGCA TGGCGTCATC 
CATCGCGATG TCAAACCCTC CAACATCCTG CTAGATGAGC GGGGCCAGAT CAAGCTCTGT 
GACTTTGGCA TCAGTGGCCG CCTTGTTGAC TCCAAAGCCA AAACACGGAG TGCTGGCTGT 
GCTGCCTATA TGGCTCCCGA GCGCATCGAC CCTCCAGATC CCACCAAGCC TGACTATGAC 
ATCCGAGCTG ATGTGTGGAG CCTGGGCATC TCACTGGTGG AGCTGGCAAC AGGACAGTTC 
CCCTATAAGA ACTGCAAGAC GGACTTTGAG GTCCTCACCA AAGTCCTACA GGAAGAGCCC 
CCACTCCTGC CTGGTCACAT GGGCTTCTCA GGGGACTTCC AGTCATTTGT CAAAGACTGC 
CTTACTAAAG ATCACAGGAA GAGACCAAAG TATAATAAGC TACTTGAACA CAGCTTCATC 
AAGCACTATG AGATACTCGA GGTGGATGTC GCGTCCTGGT TTAAGGATGT CATGGCGAAG 
ACCGAGTCCC CAAGGACTAG TGGAGTCCTG AGTCAGCACC ATCTGCCCTT CTTCAGTGGG 
AGTCTGGAGG AGTCTCCCAC TTCCCCACCT TCTCCCAAGT CCTTCCCTCT GTCACCAGCC 
ATCCCTCAGG CCCAGGCAGA GTGGGTCTCG GGCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001278706.1
CDS	171..1529
Translation	MAASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPRPTLQLPLANDGGSRSPSSESSPQHPTPPTRPRHMLGLPSTLFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKHYEILEVDVASWFKDVMAKTESPRTSGVLSQHHLPFFSGSLEESPTSPPSPKSFPLSPAIPQAQAEWVSGR

Target ORF information:

RefSeq Version	NM_001291777.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291777.1

ORF Insert Sequence:

ATGGCGGCGT CCTCCCTGGA GCAGAAGCTG TCCCGCCTGG AAGCCAAGCT GAAGCAGGAG 
AACCGTGAGG CCCGCAGGAG GATCGACCTC AACTTGGATA TCAGCCCACA GCGGCCCAGG 
CCCACCCTGC AACTCCCACT GGCCAACGAT GGGGGCAGCC GCTCACCATC CTCAGAGAGC 
TCCCCACAGC ACCCTACACC CCCCACCCGG CCCCGCCACA TGCTGGGGCT CCCATCAACC 
TTGTTCACAC CGCGCAGTAT GGAGAGCATC GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACAG GGTACCTGAC TATCGGGGGC CAGCGTTATC AGGCAGAAAT CAATGACTTG 
GAGAACTTGG GTGAGATGGG CAGTGGTACC TGTGGTCAGG TGTGGAAGAT GCGGTTCCGG 
AAGACAGGCC ACATCATTGC TGTTAAGCAA ATGCGGCGCT CTGGGAACAA GGAAGAGAAT 
AAGCGCATTT TGATGGACCT GGATGTAGTA CTCAAGAGCC ATGACTGCCC TTACATCGTT 
CAGTGCTTTG GCACCTTCAT CACCAACACA GACGTCTTTA TTGCCATGGA GCTCATGGGC 
ACATGTGCAG AGAAGCTGAA GAAACGAATG CAGGGCCCCA TTCCAGAGCG AATCCTGGGC 
AAGATGACTG TGGCGATTGT GAAAGCACTG TACTATCTGA AGGAGAAGCA TGGCGTCATC 
CATCGCGATG TCAAACCCTC CAACATCCTG CTAGATGAGC GGGGCCAGAT CAAGCTCTGT 
GACTTTGGCA TCAGTGGCCG CCTTGTTGAC TCCAAAGCCA AAACACGGAG TGCTGGCTGT 
GCTGCCTATA TGGCTCCCGA GCGCATCGAC CCTCCAGATC CCACCAAGCC TGACTATGAC 
ATCCGAGCTG ATGTGTGGAG CCTGGGCATC TCACTGGTGG AGCTGGCAAC AGGACAGTTC 
CCCTATAAGA ACTGCAAGAC GGACTTTGAG GTCCTCACCA AAGTCCTACA GGAAGAGCCC 
CCACTCCTGC CTGGTCACAT GGGCTTCTCA GGGGACTTCC AGTCATTTGT CAAAGACTGC 
CTTACTAAAG ATCACAGGAA GAGACCAAAG TATAATAAGC TACTTGAACA CAGCTTCATC 
AAGCACTATG AGATACTCGA GGTGGATGTC GCGTCCTGGT TTAAGGATGT CATGGCGAAG 
ACCGAGTCCC CAAGGACTAG TGGAGTCCTG AGTCAGCACC ATCTGCCCTT CTTCAGTGGG 
AGTCTGGAGG AGTCTCCCAC TTCCCCACCT TCTCCCAAGT CCTTCCCTCT GTCACCAGCC 
ATCCCTCAGG CCCAGGCAGA GTGGGTCTCG GGCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Map2k7 ( NM_001291778.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001278707.1 Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu18495
Clone ID Related Accession (Same CDS sequence)	NM_001291778.1
Accession Version	NM_001291778.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	dual specificity mitogen-activated protein kinase kinase 7 isoform 5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC123029.3 and AB005654.1. Transcript Variant: This variant (5) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (5) is shorter at the N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF060943.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849379, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGGGGC TCCCATCAAC CTTGTTCACA CCGCGCAGTA TGGAGAGCAT CGAGATTGAC 
CAGAAGCTGC AGGAGATCAT GAAGCAGACA GGGTACCTGA CTATCGGGGG CCAGCGTTAT 
CAGGCAGAAA TCAATGACTT GGAGAACTTG GGTGAGATGG GCAGTGGTAC CTGTGGTCAG 
GTGTGGAAGA TGCGGTTCCG GAAGACAGGC CACATCATTG CTGTTAAGCA AATGCGGCGC 
TCTGGGAACA AGGAAGAGAA TAAGCGCATT TTGATGGACC TGGATGTAGT ACTCAAGAGC 
CATGACTGCC CTTACATCGT TCAGTGCTTT GGCACCTTCA TCACCAACAC AGACGTCTTT 
ATTGCCATGG AGCTCATGGG CACATGTGCA GAGAAGCTGA AGAAACGAAT GCAGGGCCCC 
ATTCCAGAGC GAATCCTGGG CAAGATGACT GTGGCGATTG TGAAAGCACT GTACTATCTG 
AAGGAGAAGC ATGGCGTCAT CCATCGCGAT GTCAAACCCT CCAACATCCT GCTAGATGAG 
CGGGGCCAGA TCAAGCTCTG TGACTTTGGC ATCAGTGGCC GCCTTGTTGA CTCCAAAGCC 
AAAACACGGA GTGCTGGCTG TGCTGCCTAT ATGGCTCCCG AGCGCATCGA CCCTCCAGAT 
CCCACCAAGC CTGACTATGA CATCCGAGCT GATGTGTGGA GCCTGGGCAT CTCACTGGTG 
GAGCTGGCAA CAGGACAGTT CCCCTATAAG AACTGCAAGA CGGACTTTGA GGTCCTCACC 
AAAGTCCTAC AGGAAGAGCC CCCACTCCTG CCTGGTCACA TGGGCTTCTC AGGGGACTTC 
CAGTCATTTG TCAAAGACTG CCTTACTAAA GATCACAGGA AGAGACCAAA GTATAATAAG 
CTACTTGAAC ACAGCTTCAT CAAGCACTAT GAGATACTCG AGGTGGATGT CGCGTCCTGG 
TTTAAGGATG TCATGGCGAA GACCGAGTCC CCAAGGACTA GTGGAGTCCT GAGTCAGCAC 
CATCTGCCCT TCTTCAGTGG GAGTCTGGAG GAGTCTCCCA CTTCCCCACC TTCTCCCAAG 
TCCTTCCCTC TGTCACCAGC CATCCCTCAG GCCCAGGCAG AGTGGGTCTC GGGCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001278707.1
CDS	281..1420
Translation	MLGLPSTLFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKHYEILEVDVASWFKDVMAKTESPRTSGVLSQHHLPFFSGSLEESPTSPPSPKSFPLSPAIPQAQAEWVSGR

Target ORF information:

RefSeq Version	NM_001291778.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291778.1

ORF Insert Sequence:

ATGCTGGGGC TCCCATCAAC CTTGTTCACA CCGCGCAGTA TGGAGAGCAT CGAGATTGAC 
CAGAAGCTGC AGGAGATCAT GAAGCAGACA GGGTACCTGA CTATCGGGGG CCAGCGTTAT 
CAGGCAGAAA TCAATGACTT GGAGAACTTG GGTGAGATGG GCAGTGGTAC CTGTGGTCAG 
GTGTGGAAGA TGCGGTTCCG GAAGACAGGC CACATCATTG CTGTTAAGCA AATGCGGCGC 
TCTGGGAACA AGGAAGAGAA TAAGCGCATT TTGATGGACC TGGATGTAGT ACTCAAGAGC 
CATGACTGCC CTTACATCGT TCAGTGCTTT GGCACCTTCA TCACCAACAC AGACGTCTTT 
ATTGCCATGG AGCTCATGGG CACATGTGCA GAGAAGCTGA AGAAACGAAT GCAGGGCCCC 
ATTCCAGAGC GAATCCTGGG CAAGATGACT GTGGCGATTG TGAAAGCACT GTACTATCTG 
AAGGAGAAGC ATGGCGTCAT CCATCGCGAT GTCAAACCCT CCAACATCCT GCTAGATGAG 
CGGGGCCAGA TCAAGCTCTG TGACTTTGGC ATCAGTGGCC GCCTTGTTGA CTCCAAAGCC 
AAAACACGGA GTGCTGGCTG TGCTGCCTAT ATGGCTCCCG AGCGCATCGA CCCTCCAGAT 
CCCACCAAGC CTGACTATGA CATCCGAGCT GATGTGTGGA GCCTGGGCAT CTCACTGGTG 
GAGCTGGCAA CAGGACAGTT CCCCTATAAG AACTGCAAGA CGGACTTTGA GGTCCTCACC 
AAAGTCCTAC AGGAAGAGCC CCCACTCCTG CCTGGTCACA TGGGCTTCTC AGGGGACTTC 
CAGTCATTTG TCAAAGACTG CCTTACTAAA GATCACAGGA AGAGACCAAA GTATAATAAG 
CTACTTGAAC ACAGCTTCAT CAAGCACTAT GAGATACTCG AGGTGGATGT CGCGTCCTGG 
TTTAAGGATG TCATGGCGAA GACCGAGTCC CCAAGGACTA GTGGAGTCCT GAGTCAGCAC 
CATCTGCCCT TCTTCAGTGG GAGTCTGGAG GAGTCTCCCA CTTCCCCACC TTCTCCCAAG 
TCCTTCCCTC TGTCACCAGC CATCCCTCAG GCCCAGGCAG AGTGGGTCTC GGGCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Map2k7 ( NM_001164172.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001157644.1 Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 3, mRNA.

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CloneID	OMu18496
Clone ID Related Accession (Same CDS sequence)	NM_001164172.1
Accession Version	NM_001164172.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	dual specificity mitogen-activated protein kinase kinase 7 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB842920.1, BC070467.1 and AC123029.3. Transcript Variant: This variant (3) retains the last intron compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC070467.1, AF060946.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGT CCTCCCTGGA GCAGAAGCTG TCCCGCCTGG AAGCCAAGCT GAAGCAGGAG 
AACCGTGAGG CCCGCAGGAG GATCGACCTC AACTTGGATA TCAGCCCACA GCGGCCCAGG 
CCCATTATTG TGATCACTCT AAGCCCTGCT CCTGCCCCGT CCCAGCGAGC AGCCCTGCAA 
CTCCCACTGG CCAACGATGG GGGCAGCCGC TCACCATCCT CAGAGAGCTC CCCACAGCAC 
CCTACACCCC CCACCCGGCC CCGCCACATG CTGGGGCTCC CATCAACCTT GTTCACACCG 
CGCAGTATGG AGAGCATCGA GATTGACCAG AAGCTGCAGG AGATCATGAA GCAGACAGGG 
TACCTGACTA TCGGGGGCCA GCGTTATCAG GCAGAAATCA ATGACTTGGA GAACTTGGGT 
GAGATGGGCA GTGGTACCTG TGGTCAGGTG TGGAAGATGC GGTTCCGGAA GACAGGCCAC 
ATCATTGCTG TTAAGCAAAT GCGGCGCTCT GGGAACAAGG AAGAGAATAA GCGCATTTTG 
ATGGACCTGG ATGTAGTACT CAAGAGCCAT GACTGCCCTT ACATCGTTCA GTGCTTTGGC 
ACCTTCATCA CCAACACAGA CGTCTTTATT GCCATGGAGC TCATGGGCAC ATGTGCAGAG 
AAGCTGAAGA AACGAATGCA GGGCCCCATT CCAGAGCGAA TCCTGGGCAA GATGACTGTG 
GCGATTGTGA AAGCACTGTA CTATCTGAAG GAGAAGCATG GCGTCATCCA TCGCGATGTC 
AAACCCTCCA ACATCCTGCT AGATGAGCGG GGCCAGATCA AGCTCTGTGA CTTTGGCATC 
AGTGGCCGCC TTGTTGACTC CAAAGCCAAA ACACGGAGTG CTGGCTGTGC TGCCTATATG 
GCTCCCGAGC GCATCGACCC TCCAGATCCC ACCAAGCCTG ACTATGACAT CCGAGCTGAT 
GTGTGGAGCC TGGGCATCTC ACTGGTGGAG CTGGCAACAG GACAGTTCCC CTATAAGAAC 
TGCAAGACGG ACTTTGAGGT CCTCACCAAA GTCCTACAGG AAGAGCCCCC ACTCCTGCCT 
GGTCACATGG GCTTCTCAGG GGACTTCCAG TCATTTGTCA AAGACTGCCT TACTAAAGAT 
CACAGGAAGA GACCAAAGTA TAATAAGCTA CTTGAACACA GCTTCATCAA GCACTATGAG 
ATACTCGAGG TGGATGTCGC GTCCTGGTTT AAGGATGTCA TGGCGAAGAC CGAGTCCCCA 
AGGACTAGTG GAGTCCTGAG TCAGCACCAT CTGCCCTTCT TCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157644.1
CDS	171..1478
Translation	MAASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPRPIIVITLSPAPAPSQRAALQLPLANDGGSRSPSSESSPQHPTPPTRPRHMLGLPSTLFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKHYEILEVDVASWFKDVMAKTESPRTSGVLSQHHLPFFR

Target ORF information:

RefSeq Version	NM_001164172.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001164172.1

ORF Insert Sequence:

ATGGCGGCGT CCTCCCTGGA GCAGAAGCTG TCCCGCCTGG AAGCCAAGCT GAAGCAGGAG 
AACCGTGAGG CCCGCAGGAG GATCGACCTC AACTTGGATA TCAGCCCACA GCGGCCCAGG 
CCCATTATTG TGATCACTCT AAGCCCTGCT CCTGCCCCGT CCCAGCGAGC AGCCCTGCAA 
CTCCCACTGG CCAACGATGG GGGCAGCCGC TCACCATCCT CAGAGAGCTC CCCACAGCAC 
CCTACACCCC CCACCCGGCC CCGCCACATG CTGGGGCTCC CATCAACCTT GTTCACACCG 
CGCAGTATGG AGAGCATCGA GATTGACCAG AAGCTGCAGG AGATCATGAA GCAGACAGGG 
TACCTGACTA TCGGGGGCCA GCGTTATCAG GCAGAAATCA ATGACTTGGA GAACTTGGGT 
GAGATGGGCA GTGGTACCTG TGGTCAGGTG TGGAAGATGC GGTTCCGGAA GACAGGCCAC 
ATCATTGCTG TTAAGCAAAT GCGGCGCTCT GGGAACAAGG AAGAGAATAA GCGCATTTTG 
ATGGACCTGG ATGTAGTACT CAAGAGCCAT GACTGCCCTT ACATCGTTCA GTGCTTTGGC 
ACCTTCATCA CCAACACAGA CGTCTTTATT GCCATGGAGC TCATGGGCAC ATGTGCAGAG 
AAGCTGAAGA AACGAATGCA GGGCCCCATT CCAGAGCGAA TCCTGGGCAA GATGACTGTG 
GCGATTGTGA AAGCACTGTA CTATCTGAAG GAGAAGCATG GCGTCATCCA TCGCGATGTC 
AAACCCTCCA ACATCCTGCT AGATGAGCGG GGCCAGATCA AGCTCTGTGA CTTTGGCATC 
AGTGGCCGCC TTGTTGACTC CAAAGCCAAA ACACGGAGTG CTGGCTGTGC TGCCTATATG 
GCTCCCGAGC GCATCGACCC TCCAGATCCC ACCAAGCCTG ACTATGACAT CCGAGCTGAT 
GTGTGGAGCC TGGGCATCTC ACTGGTGGAG CTGGCAACAG GACAGTTCCC CTATAAGAAC 
TGCAAGACGG ACTTTGAGGT CCTCACCAAA GTCCTACAGG AAGAGCCCCC ACTCCTGCCT 
GGTCACATGG GCTTCTCAGG GGACTTCCAG TCATTTGTCA AAGACTGCCT TACTAAAGAT 
CACAGGAAGA GACCAAAGTA TAATAAGCTA CTTGAACACA GCTTCATCAA GCACTATGAG 
ATACTCGAGG TGGATGTCGC GTCCTGGTTT AAGGATGTCA TGGCGAAGAC CGAGTCCCCA 
AGGACTAGTG GAGTCCTGAG TCAGCACCAT CTGCCCTTCT TCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Map2k7 ( NM_011944.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_036074.2 Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 2, mRNA.

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CloneID	OMu18497
Clone ID Related Accession (Same CDS sequence)	NM_011944.3
Accession Version	NM_011944.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Mus musculus(house mouse)
Product	dual specificity mitogen-activated protein kinase kinase 7 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB842920.1, AK165184.1, AC123029.3 and CO044477.1. On Aug 13, 2009 this sequence version replaced NM_011944.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region and retains the last intron compared to variant 1. The resulting isoform (2) lacks an alternate internal segment and has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK165184.1, AK031137.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGT CCTCCCTGGA GCAGAAGCTG TCCCGCCTGG AAGCCAAGCT GAAGCAGGAG 
AACCGTGAGG CCCGCAGGAG GATCGACCTC AACTTGGATA TCAGCCCACA GCGGCCCAGG 
CCCACCCTGC AACTCCCACT GGCCAACGAT GGGGGCAGCC GCTCACCATC CTCAGAGAGC 
TCCCCACAGC ACCCTACACC CCCCACCCGG CCCCGCCACA TGCTGGGGCT CCCATCAACC 
TTGTTCACAC CGCGCAGTAT GGAGAGCATC GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACAG GGTACCTGAC TATCGGGGGC CAGCGTTATC AGGCAGAAAT CAATGACTTG 
GAGAACTTGG GTGAGATGGG CAGTGGTACC TGTGGTCAGG TGTGGAAGAT GCGGTTCCGG 
AAGACAGGCC ACATCATTGC TGTTAAGCAA ATGCGGCGCT CTGGGAACAA GGAAGAGAAT 
AAGCGCATTT TGATGGACCT GGATGTAGTA CTCAAGAGCC ATGACTGCCC TTACATCGTT 
CAGTGCTTTG GCACCTTCAT CACCAACACA GACGTCTTTA TTGCCATGGA GCTCATGGGC 
ACATGTGCAG AGAAGCTGAA GAAACGAATG CAGGGCCCCA TTCCAGAGCG AATCCTGGGC 
AAGATGACTG TGGCGATTGT GAAAGCACTG TACTATCTGA AGGAGAAGCA TGGCGTCATC 
CATCGCGATG TCAAACCCTC CAACATCCTG CTAGATGAGC GGGGCCAGAT CAAGCTCTGT 
GACTTTGGCA TCAGTGGCCG CCTTGTTGAC TCCAAAGCCA AAACACGGAG TGCTGGCTGT 
GCTGCCTATA TGGCTCCCGA GCGCATCGAC CCTCCAGATC CCACCAAGCC TGACTATGAC 
ATCCGAGCTG ATGTGTGGAG CCTGGGCATC TCACTGGTGG AGCTGGCAAC AGGACAGTTC 
CCCTATAAGA ACTGCAAGAC GGACTTTGAG GTCCTCACCA AAGTCCTACA GGAAGAGCCC 
CCACTCCTGC CTGGTCACAT GGGCTTCTCA GGGGACTTCC AGTCATTTGT CAAAGACTGC 
CTTACTAAAG ATCACAGGAA GAGACCAAAG TATAATAAGC TACTTGAACA CAGCTTCATC 
AAGCACTATG AGATACTCGA GGTGGATGTC GCGTCCTGGT TTAAGGATGT CATGGCGAAG 
ACCGAGTCCC CAAGGACTAG TGGAGTCCTG AGTCAGCACC ATCTGCCCTT CTTCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036074.2
CDS	171..1430
Translation	MAASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPRPTLQLPLANDGGSRSPSSESSPQHPTPPTRPRHMLGLPSTLFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKHYEILEVDVASWFKDVMAKTESPRTSGVLSQHHLPFFR

Target ORF information:

RefSeq Version	NM_011944.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011944.3

ORF Insert Sequence:

ATGGCGGCGT CCTCCCTGGA GCAGAAGCTG TCCCGCCTGG AAGCCAAGCT GAAGCAGGAG 
AACCGTGAGG CCCGCAGGAG GATCGACCTC AACTTGGATA TCAGCCCACA GCGGCCCAGG 
CCCACCCTGC AACTCCCACT GGCCAACGAT GGGGGCAGCC GCTCACCATC CTCAGAGAGC 
TCCCCACAGC ACCCTACACC CCCCACCCGG CCCCGCCACA TGCTGGGGCT CCCATCAACC 
TTGTTCACAC CGCGCAGTAT GGAGAGCATC GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACAG GGTACCTGAC TATCGGGGGC CAGCGTTATC AGGCAGAAAT CAATGACTTG 
GAGAACTTGG GTGAGATGGG CAGTGGTACC TGTGGTCAGG TGTGGAAGAT GCGGTTCCGG 
AAGACAGGCC ACATCATTGC TGTTAAGCAA ATGCGGCGCT CTGGGAACAA GGAAGAGAAT 
AAGCGCATTT TGATGGACCT GGATGTAGTA CTCAAGAGCC ATGACTGCCC TTACATCGTT 
CAGTGCTTTG GCACCTTCAT CACCAACACA GACGTCTTTA TTGCCATGGA GCTCATGGGC 
ACATGTGCAG AGAAGCTGAA GAAACGAATG CAGGGCCCCA TTCCAGAGCG AATCCTGGGC 
AAGATGACTG TGGCGATTGT GAAAGCACTG TACTATCTGA AGGAGAAGCA TGGCGTCATC 
CATCGCGATG TCAAACCCTC CAACATCCTG CTAGATGAGC GGGGCCAGAT CAAGCTCTGT 
GACTTTGGCA TCAGTGGCCG CCTTGTTGAC TCCAAAGCCA AAACACGGAG TGCTGGCTGT 
GCTGCCTATA TGGCTCCCGA GCGCATCGAC CCTCCAGATC CCACCAAGCC TGACTATGAC 
ATCCGAGCTG ATGTGTGGAG CCTGGGCATC TCACTGGTGG AGCTGGCAAC AGGACAGTTC 
CCCTATAAGA ACTGCAAGAC GGACTTTGAG GTCCTCACCA AAGTCCTACA GGAAGAGCCC 
CCACTCCTGC CTGGTCACAT GGGCTTCTCA GGGGACTTCC AGTCATTTGT CAAAGACTGC 
CTTACTAAAG ATCACAGGAA GAGACCAAAG TATAATAAGC TACTTGAACA CAGCTTCATC 
AAGCACTATG AGATACTCGA GGTGGATGTC GCGTCCTGGT TTAAGGATGT CATGGCGAAG 
ACCGAGTCCC CAAGGACTAG TGGAGTCCTG AGTCAGCACC ATCTGCCCTT CTTCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Map2k7 ( NM_001291783.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001278712.1 Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OMu18498
Clone ID Related Accession (Same CDS sequence)	NM_001291783.1
Accession Version	NM_001291783.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	dual specificity mitogen-activated protein kinase kinase 7 isoform 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC123029.3, AF060944.1, AK049267.1 and BC070467.1. On Apr 26, 2014 this sequence version replaced XM_006508805.1. Transcript Variant: This variant (6) differs in the 5' UTR and coding sequence and retains the last intron compared to variant 1. The resulting isoform (6) is shorter at the N-terminus and has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U93030.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849379, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGGGGC TCCCATCAAC CTTGTTCACA CCGCGCAGTA TGGAGAGCAT CGAGATTGAC 
CAGAAGCTGC AGGAGATCAT GAAGCAGACA GGGTACCTGA CTATCGGGGG CCAGCGTTAT 
CAGGCAGAAA TCAATGACTT GGAGAACTTG GGTGAGATGG GCAGTGGTAC CTGTGGTCAG 
GTGTGGAAGA TGCGGTTCCG GAAGACAGGC CACATCATTG CTGTTAAGCA AATGCGGCGC 
TCTGGGAACA AGGAAGAGAA TAAGCGCATT TTGATGGACC TGGATGTAGT ACTCAAGAGC 
CATGACTGCC CTTACATCGT TCAGTGCTTT GGCACCTTCA TCACCAACAC AGACGTCTTT 
ATTGCCATGG AGCTCATGGG CACATGTGCA GAGAAGCTGA AGAAACGAAT GCAGGGCCCC 
ATTCCAGAGC GAATCCTGGG CAAGATGACT GTGGCGATTG TGAAAGCACT GTACTATCTG 
AAGGAGAAGC ATGGCGTCAT CCATCGCGAT GTCAAACCCT CCAACATCCT GCTAGATGAG 
CGGGGCCAGA TCAAGCTCTG TGACTTTGGC ATCAGTGGCC GCCTTGTTGA CTCCAAAGCC 
AAAACACGGA GTGCTGGCTG TGCTGCCTAT ATGGCTCCCG AGCGCATCGA CCCTCCAGAT 
CCCACCAAGC CTGACTATGA CATCCGAGCT GATGTGTGGA GCCTGGGCAT CTCACTGGTG 
GAGCTGGCAA CAGGACAGTT CCCCTATAAG AACTGCAAGA CGGACTTTGA GGTCCTCACC 
AAAGTCCTAC AGGAAGAGCC CCCACTCCTG CCTGGTCACA TGGGCTTCTC AGGGGACTTC 
CAGTCATTTG TCAAAGACTG CCTTACTAAA GATCACAGGA AGAGACCAAA GTATAATAAG 
CTACTTGAAC ACAGCTTCAT CAAGCACTAT GAGATACTCG AGGTGGATGT CGCGTCCTGG 
TTTAAGGATG TCATGGCGAA GACCGAGTCC CCAAGGACTA GTGGAGTCCT GAGTCAGCAC 
CATCTGCCCT TCTTCAGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001278712.1
CDS	281..1321
Translation	MLGLPSTLFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKHYEILEVDVASWFKDVMAKTESPRTSGVLSQHHLPFFR

Target ORF information:

RefSeq Version	NM_001291783.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291783.1

ORF Insert Sequence:

ATGCTGGGGC TCCCATCAAC CTTGTTCACA CCGCGCAGTA TGGAGAGCAT CGAGATTGAC 
CAGAAGCTGC AGGAGATCAT GAAGCAGACA GGGTACCTGA CTATCGGGGG CCAGCGTTAT 
CAGGCAGAAA TCAATGACTT GGAGAACTTG GGTGAGATGG GCAGTGGTAC CTGTGGTCAG 
GTGTGGAAGA TGCGGTTCCG GAAGACAGGC CACATCATTG CTGTTAAGCA AATGCGGCGC 
TCTGGGAACA AGGAAGAGAA TAAGCGCATT TTGATGGACC TGGATGTAGT ACTCAAGAGC 
CATGACTGCC CTTACATCGT TCAGTGCTTT GGCACCTTCA TCACCAACAC AGACGTCTTT 
ATTGCCATGG AGCTCATGGG CACATGTGCA GAGAAGCTGA AGAAACGAAT GCAGGGCCCC 
ATTCCAGAGC GAATCCTGGG CAAGATGACT GTGGCGATTG TGAAAGCACT GTACTATCTG 
AAGGAGAAGC ATGGCGTCAT CCATCGCGAT GTCAAACCCT CCAACATCCT GCTAGATGAG 
CGGGGCCAGA TCAAGCTCTG TGACTTTGGC ATCAGTGGCC GCCTTGTTGA CTCCAAAGCC 
AAAACACGGA GTGCTGGCTG TGCTGCCTAT ATGGCTCCCG AGCGCATCGA CCCTCCAGAT 
CCCACCAAGC CTGACTATGA CATCCGAGCT GATGTGTGGA GCCTGGGCAT CTCACTGGTG 
GAGCTGGCAA CAGGACAGTT CCCCTATAAG AACTGCAAGA CGGACTTTGA GGTCCTCACC 
AAAGTCCTAC AGGAAGAGCC CCCACTCCTG CCTGGTCACA TGGGCTTCTC AGGGGACTTC 
CAGTCATTTG TCAAAGACTG CCTTACTAAA GATCACAGGA AGAGACCAAA GTATAATAAG 
CTACTTGAAC ACAGCTTCAT CAAGCACTAT GAGATACTCG AGGTGGATGT CGCGTCCTGG 
TTTAAGGATG TCATGGCGAA GACCGAGTCC CCAAGGACTA GTGGAGTCCT GAGTCAGCAC 
CATCTGCCCT TCTTCAGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia.
Current biology : CB29(5)790-802.e5(2019 03)
Hwang SH,Somatilaka BN,Badgandi H,Palicharla VR,Walker R,Shelton JM,Qian F,Mukhopadhyay S

Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death.
Cell death & disease9(11)1095(2018 10)
Syc-Mazurek SB,Rausch RL,Fernandes KA,Wilson MP,Libby RT

DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.
The Journal of biological chemistry293(11)3965-3980(2018 03)
Lao Y,Yang K,Wang Z,Sun X,Zou Q,Yu X,Cheng J,Tong X,Yeh ETH,Yang J,Yi J

A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress.
Cell reports20(12)2775-2783(2017 Sep)
Kant S,Standen CL,Morel C,Jung DY,Kim JK,Swat W,Flavell RA,Davis RJ

Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.
Scientific reports7(1)7348(2017 08)
Yamasaki T,Deki-Arima N,Kaneko A,Miyamura N,Iwatsuki M,Matsuoka M,Fujimori-Tonou N,Okamoto-Uchida Y,Hirayama J,Marth JD,Yamanashi Y,Kawasaki H,Yamanaka K,Penninger JM,Shibata S,Nishina H

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Map2k7 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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