Elp1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Elp1
Entrez Gene ID	230233
Full Name	inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein
Synonyms	3110040G09Rik,6030413P05,C78473,Elp1,IKAP
General protein information	Preferred Names inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein Names elongator complex protein 1 IKK complex-associated protein IKK-complex-associated protein IKAP ikappaB kinase complex-associated protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4 B3\|4 31.66 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_030253419.1	XP_030109279.1	elongator complex protein 1 isoform X1
NM_026079.3	NP_080355.2	elongator complex protein 1

Pathways from BioSystems

Homologies

Kluyveromyces lactis	KLLA0E05237g	XP_454181.1
Magnaporthe oryzae (rice blast fungus)	MGG_07174	XP_003715376.1
Pan troglodytes (chimpanzee)	IKBKAP	XP_001143066.2
Macaca mulatta (Rhesus monkey)	LOC713524	XP_002808145.1
Rattus norvegicus (Norway rat)	Ikbkap	NP_543175.1
Bos taurus (cattle)	IKBKAP	XP_003586478.2
Gallus gallus (chicken)	IKBKAP	XP_003643119.1
Danio rerio (zebrafish)	ikbkap	XP_689534.5
Drosophila melanogaster (fruit fly)	Elp1	NP_001262478.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003979	XP_318429.4
Xenopus tropicalis (tropical clawed frog)	ikbkap	NP_001123686.1
Schizosaccharomyces pombe (fission yeast)	iki3	NP_595335.1
Eremothecium gossypii	AGOS_AER047C	NP_984907.2
Oryza sativa (rice)	Os07g0563700	NP_001059998.1
Homo sapiens (human)	IKBKAP	NP_003631.2
Canis lupus familiaris (dog)	IKBKAP	XP_005626959.1
Arabidopsis thaliana (thale cress)	ABO1	NP_196872.1
Mus musculus (house mouse)	Ikbkap	NP_080355.2
Saccharomyces cerevisiae (baker's yeast)	IKI3	NP_013488.3
Neurospora crassa	NCU01486	XP_956763.1

Gene Ontology
Bibliography

Related articles in PubMed

Proteostasis is essential during cochlear development for neuron survival and hair cell polarity.
Freeman S, Mateo Sánchez S, Pouyo R, Van Lerberghe PB, Hanon K, Thelen N, Thiry M, Morelli G, Van Hees L, Laguesse S, Chariot A, Nguyen L, Delacroix L, Malgrange B
EMBO reports20(9)e47097(2019 09)

Retina-specific loss of
Ueki Y, Shchepetkina V, Lefcort F
Disease models & mechanisms11(7)(2018 07)

Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model.
Donadon I, Pinotti M, Rajkowska K, Pianigiani G, Barbon E, Morini E, Motaln H, Rogelj B, Mingozzi F, Slaugenhaupt SA, Pagani F
Human molecular genetics27(14)2466-2476(2018 07)

Elongator and codon bias regulate protein levels in mammalian peripheral neurons.
Goffena J, Lefcort F, Zhang Y, Lehrmann E, Chaverra M, Felig J, Walters J, Buksch R, Becker KG, George L
Nature communications9(1)889(2018 03)

RBM24 promotes U1 snRNP recognition of the mutated 5' splice site in the
Ohe K, Yoshida M, Nakano-Kobayashi A, Hosokawa M, Sako Y, Sakuma M, Okuno Y, Usui T, Ninomiya K, Nojima T, Kataoka N, Hagiwara M
RNA (New York, N.Y.)23(9)1393-1403(2017 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Elp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Elp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu88492	XM_030253419.1 Latest version!	Mus musculus elongator complex protein 1 (Elp1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu21097	NM_026079.3 Latest version!	Mus musculus elongator complex protein 1 (Elp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$783.30 $1119.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Elp1 ( XM_030253419.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030109279.1 Mus musculus elongator complex protein 1 (Elp1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu88492
Clone ID Related Accession (Same CDS sequence)	XM_030253419.1
Accession Version	XM_030253419.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1869bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	elongator complex protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAAGGG GAAACCTGGA GGTTGTTCAT CATCGGGCCT TGGTCTTGGC ACAGATTCGG 
AAGTGGCTGG ACAAACTTAT GTTTAAAGAA GCATTTGAAT GCATGAGGAA ACTGAGAATT 
AACCTCAATC TGATTCATGA CCATAACCCC AAGGTCTTTC TCGAAAATGT GGAAACCTTC 
GTAAAACAGA TTGATTCTGT AAATCATATA AATTTGTTTT TCACAGAACT CAGGGAAGAA 
GATGTCACAA AGACCATGTA CCCTCCCCCG ATTACCAAGA GTGTCCAGGT GTCCACACAT 
CCTGATGGGA AGAAACTTGA CCTCATCTGT GACGCCATGA GAGCAGCCAT GGAGGCCATC 
AATCCTCGAA AGTTCTGCCT GTCGATACTC ACATCTCATG TGAAGAAAAC CACCCCGGAG 
CTGGAAATTG TGCTGCAGAA GGTACAGGAA CTTCAAGGAA ATCTTCCCTT TGATCCTGAG 
AGTGTGAGTG TAGAGGAGGC TTTGAAATAC CTGCTGCTCC TGGTGGATGT TAATGAGTTA 
TTTAATCACT CCCTTGGGAC CTATGACTTT AATTTAGTCC TCATGGTAGC TGAGAAGTCA 
CAAAAGGATC CTAAAGAATA TCTTCCATTT CTGAATACAC TTAAGAAAAT GGAAACTAAT 
TACCAGAGGT TCACCATAGA CAAGTACTTG AAACGATATG AAAAGGCCCT TGGACACCTC 
AGCAAGTGTG GACCTGAGTA TTTCACAGAA TGCTTAAATT TGATAAAAGA TAAAAACTTG 
TATAAAGAAG CTCTCAAGTT ATATCGTCCA GACTCACCAC AGTACCAGGC GGTCAGCATG 
GCTTATGGCG AGCACCTGAT GCAGGAGCAC CTGTACGAGC CAGCAGGGCT GGTGTTTGCC 
CGCTGTGGGG CCCAGGAGAA GGCACTTGAA GCATTTTTGG CTTGTGGCAG CTGGCAGCAA 
GCCCTCTGTG TGGCTGCCCA GCTTCAGATG TCCAAAGACA AGGTGGCTGG CCTTGCTAGA 
ACTCTGGCAG GAAAGCTGGT GGAGCAGAGG AAGCACAGTG AGGCAGCCAC AGTCCTGGAA 
CAGTACGCCC AGGATTATGA AGAGGCTGTG CTCCTGCTGC TAGAAGGATC TGCCTGGGAA 
GAAGCTCTGA GGCTGGTCTA CAAGTATGAC AGAGTGGATA TTATAGAAAC CAGTGTAAAG 
CCTTCCATTT TAGAAGCCCA AAAAAATTAC ATGGACTTTC TGGACTCTGA GACAGCCACA 
TTCATTCGCC ATAAAAACCG CTTGCAGGTG GTTCGAGCGC TCAGGAGGCA AGCACCACAG 
GTCCATGTGG ATCACGAGGT GGCCCATGGC CCAGAGTCAG ACCTCTTCTC GGAAACCAGC 
AGTATTATGA GTGGCAGTGA GATGAGTGGC AGATACTCCC ACAGTAACTC CAGGATATCT 
GCGAGGTCAT CTAAAAACCG TCGGAAGGCA GAGCGCAAGA AGCATAGCCT CAAAGAAGGG 
AGTCCTCTGG AGGGCCTGGC TCTTCTGGAG GCGCTGAGTG AAGTGGTACA AAGTGTTGAG 
AAGCTAAAAG ATGAGGTGCG TGCTATTTTG AAGGTGCTCT TTCTCTTTGA GTTTGAAGAG 
CAAGCAAAGG AGTTACAGAG AGCCTTTGAG AGTACTCTGC AGCTGATGGA GAGGGCAGTT 
CCAGAGATCT GGACTCCTGC CGGCCAACAG AGTTCAACCA CACCGGTCCT AGGTCCCAGC 
TCCACTGCGA ATAGCATCAC AGCCTCTTAC CAGCAGCAGA AGACTTGTGT CCCTGCTCTC 
GATGCTGGGG TTTATATGCC ACCGAAGATG GACCCGAGAA GCCAGTGGAA GCTGAGCCTG 
CTGGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030109279.1
CDS	381..2249
Translation	MPRGNLEVVHHRALVLAQIRKWLDKLMFKEAFECMRKLRINLNLIHDHNPKVFLENVETFVKQIDSVNHINLFFTELREEDVTKTMYPPPITKSVQVSTHPDGKKLDLICDAMRAAMEAINPRKFCLSILTSHVKKTTPELEIVLQKVQELQGNLPFDPESVSVEEALKYLLLLVDVNELFNHSLGTYDFNLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFTIDKYLKRYEKALGHLSKCGPEYFTECLNLIKDKNLYKEALKLYRPDSPQYQAVSMAYGEHLMQEHLYEPAGLVFARCGAQEKALEAFLACGSWQQALCVAAQLQMSKDKVAGLARTLAGKLVEQRKHSEAATVLEQYAQDYEEAVLLLLEGSAWEEALRLVYKYDRVDIIETSVKPSILEAQKNYMDFLDSETATFIRHKNRLQVVRALRRQAPQVHVDHEVAHGPESDLFSETSSIMSGSEMSGRYSHSNSRISARSSKNRRKAERKKHSLKEGSPLEGLALLEALSEVVQSVEKLKDEVRAILKVLFLFEFEEQAKELQRAFESTLQLMERAVPEIWTPAGQQSSTTPVLGPSSTANSITASYQQQKTCVPALDAGVYMPPKMDPRSQWKLSLLE

Target ORF information:

RefSeq Version	XM_030253419.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus elongator complex protein 1 (Elp1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030253419.1

ORF Insert Sequence:

ATGCCAAGGG GAAACCTGGA GGTTGTTCAT CATCGGGCCT TGGTCTTGGC ACAGATTCGG 
AAGTGGCTGG ACAAACTTAT GTTTAAAGAA GCATTTGAAT GCATGAGGAA ACTGAGAATT 
AACCTCAATC TGATTCATGA CCATAACCCC AAGGTCTTTC TCGAAAATGT GGAAACCTTC 
GTAAAACAGA TTGATTCTGT AAATCATATA AATTTGTTTT TCACAGAACT CAGGGAAGAA 
GATGTCACAA AGACCATGTA CCCTCCCCCG ATTACCAAGA GTGTCCAGGT GTCCACACAT 
CCTGATGGGA AGAAACTTGA CCTCATCTGT GACGCCATGA GAGCAGCCAT GGAGGCCATC 
AATCCTCGAA AGTTCTGCCT GTCGATACTC ACATCTCATG TGAAGAAAAC CACCCCGGAG 
CTGGAAATTG TGCTGCAGAA GGTACAGGAA CTTCAAGGAA ATCTTCCCTT TGATCCTGAG 
AGTGTGAGTG TAGAGGAGGC TTTGAAATAC CTGCTGCTCC TGGTGGATGT TAATGAGTTA 
TTTAATCACT CCCTTGGGAC CTATGACTTT AATTTAGTCC TCATGGTAGC TGAGAAGTCA 
CAAAAGGATC CTAAAGAATA TCTTCCATTT CTGAATACAC TTAAGAAAAT GGAAACTAAT 
TACCAGAGGT TCACCATAGA CAAGTACTTG AAACGATATG AAAAGGCCCT TGGACACCTC 
AGCAAGTGTG GACCTGAGTA TTTCACAGAA TGCTTAAATT TGATAAAAGA TAAAAACTTG 
TATAAAGAAG CTCTCAAGTT ATATCGTCCA GACTCACCAC AGTACCAGGC GGTCAGCATG 
GCTTATGGCG AGCACCTGAT GCAGGAGCAC CTGTACGAGC CAGCAGGGCT GGTGTTTGCC 
CGCTGTGGGG CCCAGGAGAA GGCACTTGAA GCATTTTTGG CTTGTGGCAG CTGGCAGCAA 
GCCCTCTGTG TGGCTGCCCA GCTTCAGATG TCCAAAGACA AGGTGGCTGG CCTTGCTAGA 
ACTCTGGCAG GAAAGCTGGT GGAGCAGAGG AAGCACAGTG AGGCAGCCAC AGTCCTGGAA 
CAGTACGCCC AGGATTATGA AGAGGCTGTG CTCCTGCTGC TAGAAGGATC TGCCTGGGAA 
GAAGCTCTGA GGCTGGTCTA CAAGTATGAC AGAGTGGATA TTATAGAAAC CAGTGTAAAG 
CCTTCCATTT TAGAAGCCCA AAAAAATTAC ATGGACTTTC TGGACTCTGA GACAGCCACA 
TTCATTCGCC ATAAAAACCG CTTGCAGGTG GTTCGAGCGC TCAGGAGGCA AGCACCACAG 
GTCCATGTGG ATCACGAGGT GGCCCATGGC CCAGAGTCAG ACCTCTTCTC GGAAACCAGC 
AGTATTATGA GTGGCAGTGA GATGAGTGGC AGATACTCCC ACAGTAACTC CAGGATATCT 
GCGAGGTCAT CTAAAAACCG TCGGAAGGCA GAGCGCAAGA AGCATAGCCT CAAAGAAGGG 
AGTCCTCTGG AGGGCCTGGC TCTTCTGGAG GCGCTGAGTG AAGTGGTACA AAGTGTTGAG 
AAGCTAAAAG ATGAGGTGCG TGCTATTTTG AAGGTGCTCT TTCTCTTTGA GTTTGAAGAG 
CAAGCAAAGG AGTTACAGAG AGCCTTTGAG AGTACTCTGC AGCTGATGGA GAGGGCAGTT 
CCAGAGATCT GGACTCCTGC CGGCCAACAG AGTTCAACCA CACCGGTCCT AGGTCCCAGC 
TCCACTGCGA ATAGCATCAC AGCCTCTTAC CAGCAGCAGA AGACTTGTGT CCCTGCTCTC 
GATGCTGGGG TTTATATGCC ACCGAAGATG GACCCGAGAA GCCAGTGGAA GCTGAGCCTG 
CTGGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Elp1 ( NM_026079.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080355.2 Mus musculus elongator complex protein 1 (Elp1), mRNA.

Price & Availability↑

CloneID	OMu21097
Clone ID Related Accession (Same CDS sequence)	NM_026079.3
Accession Version	NM_026079.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576425600000
Organism	Mus musculus(house mouse)
Product	elongator complex protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK035944.1, AK147153.1, AK165168.1, AK032563.1 and AK076152.1. On Oct 31, 2007 this sequence version replaced NM_026079.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF387811.1, AF140786.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGAGAAATC TGAAGTTGCA TCGGACCCTG GAGTTTCGGG ACATTCAGGC ACCAGGGAAA 
CCTCAGTGTT TCTGTCTGCG AGCTGAGCAG GGCACGGTGC TGATTGGCTC AGAACGTGGA 
CTGACGGAAG TAGATCCTGT GAGAAGAGAA GTGAAGACTG AAATTTCTTT GGTGGCAGAA 
GGTTTTCTTC CAGAGGATGG AAGTGGCTGC ATTGTGGGTA TTCAGGACTT GCTGGATCAG 
GAATCTGTGT GTGTGGCCAC CGCCTCTGGG GACGTCATAG TCTGCAATCT CAGCACACAG 
CAGCTGGAAT GTGTTGGGAG TGTGGCCAGT GGTATCTCTG TCATGAGCTG GAGTCCTGAT 
CAAGAACTGC TGCTTCTTGC CACAGCTCAA CAGACCCTGA TTATGATGAC AAAAGACTTT 
GAAGTGATCG CAGAGGAGCA GATCCACCAG GATGATTTTG GAGAAGGCAA GTTTGTCACT 
GTTGGATGGG GCAGTAAGCA GACCCAGTTC CACGGCTCAG AAGGCAGGCC AACAGCCTTT 
CCGGTGCAGT TGCCTGAGAA TGCCTTGCCC TGGGACGACC GCAGACCACA CATTACCTGG 
CGTGGGGATG GGCAGTATTT TGCTGTGAGT GTTGTTTGTC GACAAACAGA GGCTCGGAAG 
ATCCGCGTAT GGAACCGAGA GTTTGCCTTG CAGTCAACCA GTGAGTCTGT GCCAGGACTG 
GGGCCCGCCC TGGCTTGGAA ACCCTCAGGC AGTTTGATTG CATCTACTCA AGATAAACCC 
AACCAGCAAG ATGTTGTGTT TTTTGAGAAA AATGGACTTC TTCATGGACA TTTTACACTT 
CCTTTCTTAA AAGATGAAGT TAAGGTAAAT GACCTGCTGT GGAATGCAGA TTCCTCGGTG 
CTTGCTATAT GGCTAGAAGA CCTCCCAAAG GAAGACAGTT CCACTCTGAA AAGCTATGTC 
CAGCTCTGGA CCGTGGGGAA CTATCACTGG TATCTGAAGC AAAGCCTGCC CTTCAGCACC 
ACTGGGAAGA ACCAGATCGT GTCTCTGCTG TGGGACCCGG TGACGCCGTG TCGACTCCAT 
GTTCTCTGTA CGGGCTGGCG GTATCTATGC TGTGACTGGC ACTGGACCAC TGATCGGAGC 
TCTGGGAATA GTGCCAATGA CTTGGCAAAT GTGGCTGTTA TTGATGGAAA CAGGGTGTTG 
GTGACAGTCT TTCGGCAGAC GGTCGTCCCA CCTCCCATGT GTACCTACCG GCTGCTGATC 
CCACATCCAG TGAATCAAGT CATATTCTCT GCTCACCTTG GGAATGACCT TGCTGTCCTC 
GACGCCAGTA ACCAGATTTC TGTCTACAAG TGTGGTGATA AGCCAAACAT GGATTCCACA 
GTGAAACTAG GAGCCGTGGG TGGAAATGGA TTTAAAGTTC CTCTTACAAC ACCTCATTTG 
GAAAAGAGAT ACTCGATTCA GTTCGGGAAC AATGAAGAAG AAGAAGAAGA AGAAGTAAAC 
GCACTGCAGT TGAGCTTTCT CACCTGGGTT GAAGACGACA CTTTCCTGGC TATAAGCTAC 
AGTCACTCCA GCTCACAGTC CATCATTCAC CATTTGACTG TGACCCATTC TGAGGTGGAT 
GAGGAGCAAG GCCAGCTGGA TGTCAGTTCG TCTGTGACAG TGGATGGAGT CGTCATTGGT 
TTATGCTGCT GTTCTAAGAC CAAGTCATTA GCAGTACAGC TGGCTGATGG CCAGGTGCTC 
AAGTACCTTT GGGAGTCACC TTCTCTGGCT GTGGAACCCT GGAAGAATTC TGAAGGAATT 
CCTGTTCGAT TTGTTCATCC ATGCACACAG ATGGAAGTAG CCACGATTGG AGGAGAGGAA 
TGTGTCCTTG GTCTGACTGA CAGGTGTCGC TTTTTTATCA ATGACACTGA GGTCGCATCA 
AATATCACGT CATTTGCTGT GTGTGATGAC TTTCTACTGG TGACAACCCA TTCCCACACC 
TGCCAGGTTT TCTCCCTAAG TGGTGCCTCA CTTAAAATGC TACAGGCAGC TCTGAGTGGC 
AGTCATGAGG CCAGTGGAGA AATTCTGCGG AAAGTGGAAA GGGGTTCACG GATCGTGACA 
GTTGTTCCCC AGGACACAAA GCTTATACTA CAGATGCCAA GGGGAAACCT GGAGGTTGTT 
CATCATCGGG CCTTGGTCTT GGCACAGATT CGGAAGTGGC TGGACAAACT TATGTTTAAA 
GAAGCATTTG AATGCATGAG GAAACTGAGA ATTAACCTCA ATCTGATTCA TGACCATAAC 
CCCAAGGTCT TTCTCGAAAA TGTGGAAACC TTCGTAAAAC AGATTGATTC TGTAAATCAT 
ATAAATTTGT TTTTCACAGA ACTCAGGGAA GAAGATGTCA CAAAGACCAT GTACCCTCCC 
CCGATTACCA AGAGTGTCCA GGTGTCCACA CATCCTGATG GGAAGAAACT TGACCTCATC 
TGTGACGCCA TGAGAGCAGC CATGGAGGCC ATCAATCCTC GAAAGTTCTG CCTGTCGATA 
CTCACATCTC ATGTGAAGAA AACCACCCCG GAGCTGGAAA TTGTGCTGCA GAAGGTACAG 
GAACTTCAAG GAAATCTTCC CTTTGATCCT GAGAGTGTGA GTGTAGAGGA GGCTTTGAAA 
TACCTGCTGC TCCTGGTGGA TGTTAATGAG TTATTTAATC ACTCCCTTGG GACCTATGAC 
TTTAATTTAG TCCTCATGGT AGCTGAGAAG TCACAAAAGG ATCCTAAAGA ATATCTTCCA 
TTTCTGAATA CACTTAAGAA AATGGAAACT AATTACCAGA GGTTCACCAT AGACAAGTAC 
TTGAAACGAT ATGAAAAGGC CCTTGGACAC CTCAGCAAGT GTGGACCTGA GTATTTCACA 
GAATGCTTAA ATTTGATAAA AGATAAAAAC TTGTATAAAG AAGCTCTCAA GTTATATCGT 
CCAGACTCAC CACAGTACCA GGCGGTCAGC ATGGCTTATG GCGAGCACCT GATGCAGGAG 
CACCTGTACG AGCCAGCAGG GCTGGTGTTT GCCCGCTGTG GGGCCCAGGA GAAGGCACTT 
GAAGCATTTT TGGCTTGTGG CAGCTGGCAG CAAGCCCTCT GTGTGGCTGC CCAGCTTCAG 
ATGTCCAAAG ACAAGGTGGC TGGCCTTGCT AGAACTCTGG CAGGAAAGCT GGTGGAGCAG 
AGGAAGCACA GTGAGGCAGC CACAGTCCTG GAACAGTACG CCCAGGATTA TGAAGAGGCT 
GTGCTCCTGC TGCTAGAAGG ATCTGCCTGG GAAGAAGCTC TGAGGCTGGT CTACAAGTAT 
GACAGAGTGG ATATTATAGA AACCAGTGTA AAGCCTTCCA TTTTAGAAGC CCAAAAAAAT 
TACATGGACT TTCTGGACTC TGAGACAGCC ACATTCATTC GCCATAAAAA CCGCTTGCAG 
GTGGTTCGAG CGCTCAGGAG GCAAGCACCA CAGGTCCATG TGGATCACGA GGTGGCCCAT 
GGCCCAGAGT CAGACCTCTT CTCGGAAACC AGCAGTATTA TGAGTGGCAG TGAGATGAGT 
GGCAGATACT CCCACAGTAA CTCCAGGATA TCTGCGAGGT CATCTAAAAA CCGTCGGAAG 
GCAGAGCGCA AGAAGCATAG CCTCAAAGAA GGGAGTCCTC TGGAGGGCCT GGCTCTTCTG 
GAGGCGCTGA GTGAAGTGGT ACAAAGTGTT GAGAAGCTAA AAGATGAGGT GCGTGCTATT 
TTGAAGGTGC TCTTTCTCTT TGAGTTTGAA GAGCAAGCAA AGGAGTTACA GAGAGCCTTT 
GAGAGTACTC TGCAGCTGAT GGAGAGGGCA GTTCCAGAGA TCTGGACTCC TGCCGGCCAA 
CAGAGTTCAA CCACACCGGT CCTAGGTCCC AGCTCCACTG CGAATAGCAT CACAGCCTCT 
TACCAGCAGC AGAAGACTTG TGTCCCTGCT CTCGATGCTG GGGTTTATAT GCCACCGAAG 
ATGGACCCGA GAAGCCAGTG GAAGCTGAGC CTGCTGGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080355.2
CDS	187..4188
Translation	MRNLKLHRTLEFRDIQAPGKPQCFCLRAEQGTVLIGSERGLTEVDPVRREVKTEISLVAEGFLPEDGSGCIVGIQDLLDQESVCVATASGDVIVCNLSTQQLECVGSVASGISVMSWSPDQELLLLATAQQTLIMMTKDFEVIAEEQIHQDDFGEGKFVTVGWGSKQTQFHGSEGRPTAFPVQLPENALPWDDRRPHITWRGDGQYFAVSVVCRQTEARKIRVWNREFALQSTSESVPGLGPALAWKPSGSLIASTQDKPNQQDVVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSVLAIWLEDLPKEDSSTLKSYVQLWTVGNYHWYLKQSLPFSTTGKNQIVSLLWDPVTPCRLHVLCTGWRYLCCDWHWTTDRSSGNSANDLANVAVIDGNRVLVTVFRQTVVPPPMCTYRLLIPHPVNQVIFSAHLGNDLAVLDASNQISVYKCGDKPNMDSTVKLGAVGGNGFKVPLTTPHLEKRYSIQFGNNEEEEEEEVNALQLSFLTWVEDDTFLAISYSHSSSQSIIHHLTVTHSEVDEEQGQLDVSSSVTVDGVVIGLCCCSKTKSLAVQLADGQVLKYLWESPSLAVEPWKNSEGIPVRFVHPCTQMEVATIGGEECVLGLTDRCRFFINDTEVASNITSFAVCDDFLLVTTHSHTCQVFSLSGASLKMLQAALSGSHEASGEILRKVERGSRIVTVVPQDTKLILQMPRGNLEVVHHRALVLAQIRKWLDKLMFKEAFECMRKLRINLNLIHDHNPKVFLENVETFVKQIDSVNHINLFFTELREEDVTKTMYPPPITKSVQVSTHPDGKKLDLICDAMRAAMEAINPRKFCLSILTSHVKKTTPELEIVLQKVQELQGNLPFDPESVSVEEALKYLLLLVDVNELFNHSLGTYDFNLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFTIDKYLKRYEKALGHLSKCGPEYFTECLNLIKDKNLYKEALKLYRPDSPQYQAVSMAYGEHLMQEHLYEPAGLVFARCGAQEKALEAFLACGSWQQALCVAAQLQMSKDKVAGLARTLAGKLVEQRKHSEAATVLEQYAQDYEEAVLLLLEGSAWEEALRLVYKYDRVDIIETSVKPSILEAQKNYMDFLDSETATFIRHKNRLQVVRALRRQAPQVHVDHEVAHGPESDLFSETSSIMSGSEMSGRYSHSNSRISARSSKNRRKAERKKHSLKEGSPLEGLALLEALSEVVQSVEKLKDEVRAILKVLFLFEFEEQAKELQRAFESTLQLMERAVPEIWTPAGQQSSTTPVLGPSSTANSITASYQQQKTCVPALDAGVYMPPKMDPRSQWKLSLLE

Target ORF information:

RefSeq Version	NM_026079.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus elongator complex protein 1 (Elp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026079.3

ORF Insert Sequence:

ATGAGAAATC TGAAGTTGCA TCGGACCCTG GAGTTTCGGG ACATTCAGGC ACCAGGGAAA 
CCTCAGTGTT TCTGTCTGCG AGCTGAGCAG GGCACGGTGC TGATTGGCTC AGAACGTGGA 
CTGACGGAAG TAGATCCTGT GAGAAGAGAA GTGAAGACTG AAATTTCTTT GGTGGCAGAA 
GGTTTTCTTC CAGAGGATGG AAGTGGCTGC ATTGTGGGTA TTCAGGACTT GCTGGATCAG 
GAATCTGTGT GTGTGGCCAC CGCCTCTGGG GACGTCATAG TCTGCAATCT CAGCACACAG 
CAGCTGGAAT GTGTTGGGAG TGTGGCCAGT GGTATCTCTG TCATGAGCTG GAGTCCTGAT 
CAAGAACTGC TGCTTCTTGC CACAGCTCAA CAGACCCTGA TTATGATGAC AAAAGACTTT 
GAAGTGATCG CAGAGGAGCA GATCCACCAG GATGATTTTG GAGAAGGCAA GTTTGTCACT 
GTTGGATGGG GCAGTAAGCA GACCCAGTTC CACGGCTCAG AAGGCAGGCC AACAGCCTTT 
CCGGTGCAGT TGCCTGAGAA TGCCTTGCCC TGGGACGACC GCAGACCACA CATTACCTGG 
CGTGGGGATG GGCAGTATTT TGCTGTGAGT GTTGTTTGTC GACAAACAGA GGCTCGGAAG 
ATCCGCGTAT GGAACCGAGA GTTTGCCTTG CAGTCAACCA GTGAGTCTGT GCCAGGACTG 
GGGCCCGCCC TGGCTTGGAA ACCCTCAGGC AGTTTGATTG CATCTACTCA AGATAAACCC 
AACCAGCAAG ATGTTGTGTT TTTTGAGAAA AATGGACTTC TTCATGGACA TTTTACACTT 
CCTTTCTTAA AAGATGAAGT TAAGGTAAAT GACCTGCTGT GGAATGCAGA TTCCTCGGTG 
CTTGCTATAT GGCTAGAAGA CCTCCCAAAG GAAGACAGTT CCACTCTGAA AAGCTATGTC 
CAGCTCTGGA CCGTGGGGAA CTATCACTGG TATCTGAAGC AAAGCCTGCC CTTCAGCACC 
ACTGGGAAGA ACCAGATCGT GTCTCTGCTG TGGGACCCGG TGACGCCGTG TCGACTCCAT 
GTTCTCTGTA CGGGCTGGCG GTATCTATGC TGTGACTGGC ACTGGACCAC TGATCGGAGC 
TCTGGGAATA GTGCCAATGA CTTGGCAAAT GTGGCTGTTA TTGATGGAAA CAGGGTGTTG 
GTGACAGTCT TTCGGCAGAC GGTCGTCCCA CCTCCCATGT GTACCTACCG GCTGCTGATC 
CCACATCCAG TGAATCAAGT CATATTCTCT GCTCACCTTG GGAATGACCT TGCTGTCCTC 
GACGCCAGTA ACCAGATTTC TGTCTACAAG TGTGGTGATA AGCCAAACAT GGATTCCACA 
GTGAAACTAG GAGCCGTGGG TGGAAATGGA TTTAAAGTTC CTCTTACAAC ACCTCATTTG 
GAAAAGAGAT ACTCGATTCA GTTCGGGAAC AATGAAGAAG AAGAAGAAGA AGAAGTAAAC 
GCACTGCAGT TGAGCTTTCT CACCTGGGTT GAAGACGACA CTTTCCTGGC TATAAGCTAC 
AGTCACTCCA GCTCACAGTC CATCATTCAC CATTTGACTG TGACCCATTC TGAGGTGGAT 
GAGGAGCAAG GCCAGCTGGA TGTCAGTTCG TCTGTGACAG TGGATGGAGT CGTCATTGGT 
TTATGCTGCT GTTCTAAGAC CAAGTCATTA GCAGTACAGC TGGCTGATGG CCAGGTGCTC 
AAGTACCTTT GGGAGTCACC TTCTCTGGCT GTGGAACCCT GGAAGAATTC TGAAGGAATT 
CCTGTTCGAT TTGTTCATCC ATGCACACAG ATGGAAGTAG CCACGATTGG AGGAGAGGAA 
TGTGTCCTTG GTCTGACTGA CAGGTGTCGC TTTTTTATCA ATGACACTGA GGTCGCATCA 
AATATCACGT CATTTGCTGT GTGTGATGAC TTTCTACTGG TGACAACCCA TTCCCACACC 
TGCCAGGTTT TCTCCCTAAG TGGTGCCTCA CTTAAAATGC TACAGGCAGC TCTGAGTGGC 
AGTCATGAGG CCAGTGGAGA AATTCTGCGG AAAGTGGAAA GGGGTTCACG GATCGTGACA 
GTTGTTCCCC AGGACACAAA GCTTATACTA CAGATGCCAA GGGGAAACCT GGAGGTTGTT 
CATCATCGGG CCTTGGTCTT GGCACAGATT CGGAAGTGGC TGGACAAACT TATGTTTAAA 
GAAGCATTTG AATGCATGAG GAAACTGAGA ATTAACCTCA ATCTGATTCA TGACCATAAC 
CCCAAGGTCT TTCTCGAAAA TGTGGAAACC TTCGTAAAAC AGATTGATTC TGTAAATCAT 
ATAAATTTGT TTTTCACAGA ACTCAGGGAA GAAGATGTCA CAAAGACCAT GTACCCTCCC 
CCGATTACCA AGAGTGTCCA GGTGTCCACA CATCCTGATG GGAAGAAACT TGACCTCATC 
TGTGACGCCA TGAGAGCAGC CATGGAGGCC ATCAATCCTC GAAAGTTCTG CCTGTCGATA 
CTCACATCTC ATGTGAAGAA AACCACCCCG GAGCTGGAAA TTGTGCTGCA GAAGGTACAG 
GAACTTCAAG GAAATCTTCC CTTTGATCCT GAGAGTGTGA GTGTAGAGGA GGCTTTGAAA 
TACCTGCTGC TCCTGGTGGA TGTTAATGAG TTATTTAATC ACTCCCTTGG GACCTATGAC 
TTTAATTTAG TCCTCATGGT AGCTGAGAAG TCACAAAAGG ATCCTAAAGA ATATCTTCCA 
TTTCTGAATA CACTTAAGAA AATGGAAACT AATTACCAGA GGTTCACCAT AGACAAGTAC 
TTGAAACGAT ATGAAAAGGC CCTTGGACAC CTCAGCAAGT GTGGACCTGA GTATTTCACA 
GAATGCTTAA ATTTGATAAA AGATAAAAAC TTGTATAAAG AAGCTCTCAA GTTATATCGT 
CCAGACTCAC CACAGTACCA GGCGGTCAGC ATGGCTTATG GCGAGCACCT GATGCAGGAG 
CACCTGTACG AGCCAGCAGG GCTGGTGTTT GCCCGCTGTG GGGCCCAGGA GAAGGCACTT 
GAAGCATTTT TGGCTTGTGG CAGCTGGCAG CAAGCCCTCT GTGTGGCTGC CCAGCTTCAG 
ATGTCCAAAG ACAAGGTGGC TGGCCTTGCT AGAACTCTGG CAGGAAAGCT GGTGGAGCAG 
AGGAAGCACA GTGAGGCAGC CACAGTCCTG GAACAGTACG CCCAGGATTA TGAAGAGGCT 
GTGCTCCTGC TGCTAGAAGG ATCTGCCTGG GAAGAAGCTC TGAGGCTGGT CTACAAGTAT 
GACAGAGTGG ATATTATAGA AACCAGTGTA AAGCCTTCCA TTTTAGAAGC CCAAAAAAAT 
TACATGGACT TTCTGGACTC TGAGACAGCC ACATTCATTC GCCATAAAAA CCGCTTGCAG 
GTGGTTCGAG CGCTCAGGAG GCAAGCACCA CAGGTCCATG TGGATCACGA GGTGGCCCAT 
GGCCCAGAGT CAGACCTCTT CTCGGAAACC AGCAGTATTA TGAGTGGCAG TGAGATGAGT 
GGCAGATACT CCCACAGTAA CTCCAGGATA TCTGCGAGGT CATCTAAAAA CCGTCGGAAG 
GCAGAGCGCA AGAAGCATAG CCTCAAAGAA GGGAGTCCTC TGGAGGGCCT GGCTCTTCTG 
GAGGCGCTGA GTGAAGTGGT ACAAAGTGTT GAGAAGCTAA AAGATGAGGT GCGTGCTATT 
TTGAAGGTGC TCTTTCTCTT TGAGTTTGAA GAGCAAGCAA AGGAGTTACA GAGAGCCTTT 
GAGAGTACTC TGCAGCTGAT GGAGAGGGCA GTTCCAGAGA TCTGGACTCC TGCCGGCCAA 
CAGAGTTCAA CCACACCGGT CCTAGGTCCC AGCTCCACTG CGAATAGCAT CACAGCCTCT 
TACCAGCAGC AGAAGACTTG TGTCCCTGCT CTCGATGCTG GGGTTTATAT GCCACCGAAG 
ATGGACCCGA GAAGCCAGTG GAAGCTGAGC CTGCTGGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Proteostasis is essential during cochlear development for neuron survival and hair cell polarity.
EMBO reports20(9)e47097(2019 09)
Freeman S,Mateo Sánchez S,Pouyo R,Van Lerberghe PB,Hanon K,Thelen N,Thiry M,Morelli G,Van Hees L,Laguesse S,Chariot A,Nguyen L,Delacroix L,Malgrange B

Retina-specific loss of
Disease models & mechanisms11(7)(2018 07)
Ueki Y,Shchepetkina V,Lefcort F

Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model.
Human molecular genetics27(14)2466-2476(2018 07)
Donadon I,Pinotti M,Rajkowska K,Pianigiani G,Barbon E,Morini E,Motaln H,Rogelj B,Mingozzi F,Slaugenhaupt SA,Pagani F

Elongator and codon bias regulate protein levels in mammalian peripheral neurons.
Nature communications9(1)889(2018 03)
Goffena J,Lefcort F,Zhang Y,Lehrmann E,Chaverra M,Felig J,Walters J,Buksch R,Becker KG,George L

RBM24 promotes U1 snRNP recognition of the mutated 5' splice site in the
RNA (New York, N.Y.)23(9)1393-1403(2017 09)
Ohe K,Yoshida M,Nakano-Kobayashi A,Hosokawa M,Sako Y,Sakuma M,Okuno Y,Usui T,Ninomiya K,Nojima T,Kataoka N,Hagiwara M

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Elp1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM