Stradb cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Stradb
Entrez Gene ID	227154
Full Name	STE20-related kinase adaptor beta
Synonyms	AA792893,Als2cr2,B830008M19,D1Ucla2,ILPIP,ILPIPA,PRO1038,Papk,Syradb
General protein information	Preferred Names STE20-related kinase adaptor beta Names STE20-related kinase adapter protein beta ILP-interacting protein homolog STRAD beta amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog polyploidy associated protein kinase pseudokinase ALS2CR2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 C1.3\|1 29.2 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_172656.5	NP_766244.4	STE20-related kinase adapter protein beta
NM_172656.6	NP_766244.4	STE20-related kinase adapter protein beta

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Stradb	NP_001102777.2
Gallus gallus (chicken)	STRADB	XP_004942668.1
Macaca mulatta (Rhesus monkey)	STRADB	XP_001098785.1
Canis lupus familiaris (dog)	STRADB	XP_536030.2
Pan troglodytes (chimpanzee)	STRADB	XP_516032.3
Xenopus tropicalis (tropical clawed frog)	stradb	XP_002936585.2
Bos taurus (cattle)	STRADB	NP_001179010.2
Mus musculus (house mouse)	Stradb	NP_766244.4
Homo sapiens (human)	STRADB	NP_061041.2

Gene Ontology
Bibliography

Related articles in PubMed

STRAD pseudokinases regulate axogenesis and LKB1 stability.
Veleva-Rotse BO, Smart JL, Baas AF, Edmonds B, Zhao ZM, Brown A, Klug LR, Hansen K, Reilly G, Gardner AP, Subbiah K, Gaucher EA, Clevers H, Barnes AP
Neural development95(2014 Mar)

Characterization of the liver kinase B1-mouse protein-25 -Ste-20-related adaptor protein complex in adult mouse skeletal muscle.
Smith CD, Compton RA, Bowler JS, Kemp JT, Sudweeks SN, Thomson DM, Winder WW
Journal of applied physiology (Bethesda, Md. : 1985)111(6)1622-8(2011 Dec)

Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling.
Ling KH, Hewitt CA, Beissbarth T, Hyde L, Banerjee K, Cheah PS, Cannon PZ, Hahn CN, Thomas PQ, Smyth GK, Tan SS, Thomas T, Scott HS
Genome biology10(10)R104(2009)

LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.
Barnes AP, Lilley BN, Pan YA, Plummer LJ, Powell AW, Raines AN, Sanes JR, Polleux F
Cell129(3)549-63(2007 May)

Identification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinase.
Nishigaki K, Thompson D, Yugawa T, Rulli K, Hanson C, Cmarik J, Gutkind JS, Teramoto H, Ruscetti S
The Journal of biological chemistry278(15)13520-30(2003 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Stradb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Stradb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu03835	NM_172656.6 Latest version!	Mus musculus STE20-related kinase adaptor beta (Stradb), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OMu03835	NM_172656.5	Mus musculus STE20-related kinase adaptor beta (Stradb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Stradb ( NM_172656.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_766244.4 Mus musculus STE20-related kinase adaptor beta (Stradb), mRNA.

Price & Availability↑

CloneID	OMu03835
Clone ID Related Accession (Same CDS sequence)	NM_172656.5 , NM_172656.6
Accession Version	NM_172656.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1473264000000
Organism	Mus musculus(House mouse)
Product	STE20-related kinase adapter protein beta
Comment	VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ060534.1, AK080096.1 and AI643873.1. On Feb 14, 2006 this sequence version replaced NM_172656.4. ##Evidence-Data-START## Transcript exon combination :: BC037003.1, AK046790.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTCTTT TGGATTGTTT CTGTGCTTCA CGAACACGAG TCGAATCACT CAGACCCGAA 
AAACAGTCTG AAACCAGTAT CCATCAGTAC TTGGTTGATG AGTCAGCCAT TTCCCGGCCC 
CCTCCGTCTG CTAGAGCCAG TGAGGTGATC TGCTCCACTG ACGTGTCTCA CTATGAACTG 
CAAGTGGAGA TAGGAAGAGG GTTTGACAAC TTGACCTCTG TTCATCTTGC ACGGCACACT 
CCTACAGGAA CACTGGTAAC TGTAAAGATT ACAAACCTGG AAAGCTGCAC TGAAGAACGT 
CTGAAAGCTT TACAGAGAGC AGTGATTCTA TCTCACTTTT TCCAACATCC CAATATTACA 
ACTTATTGGA CAGTGTTCAC TGTTGGCAGC TGGCTTTGGG TTATTTCTCC ATTTATGGCC 
TACGGTTCAG CAAGTCAGCT CCTAAGGACC TACTTTCCTG ATGGAATGAG TGAGACTTTA 
ATAAGAAACA TTCTCTTTGG AGCAGTACAA GGGTTGAACT ATCTGCACCA AAATGGCTGT 
ATCCATAGGA GTTTTAAAGC CAGCCATATC CTCATTTCTG GTGATGGCCT GGTGACCCTC 
TCTGGCCTGT CCCACCTGCA TAGTTTGCTT AAGCACGGAC AAAGGCATAG GGCTGTGTTT 
GATTTCCCAC AGTTCAGCAC ATCAGTGCAG CCGTGGCTGA GTCCAGAACT ACTGAGACAG 
GATTTACATG GATATAATGT GAAGTCAGAT ATTTACAGTG TTGGGATCAC AGCCTGTGAA 
TTGGCCAGCG GGCAGGTACC TTTCCAGGAC ATGCATAGGA CTCAGATGCT ATTACAGAAA 
CTGAAAGGTC CTCCGTATAG CCCACTGGAT GTCAGTATTT TTCCTCAGTC AGACTCTAGA 
ATGAGAAATT CCCAGTCAGG AGTAGACTCT GGGATTGGAG AGAGTGTGCT TGTCTCCACT 
GGAACTCACA CAGTCAATAG TGACCGGCTC CATACGCCAT CCACAAAGAC GTTCTCTCCT 
GCCTTTTTTA GCTTGGTGCA GCTGTGTTTG CAGCAAGATC CTGAGAAAAG GCCATCAGCA 
AGCAGTTTGT TGTCCCATGT ATTCTTCAAG CAGATGAAAG AAGAAAGCCA GGATTCCATA 
CTTCCCCTGT TGCCACCTGC TTATAACAGG CCATCAGCGT CACTGCAGCC AGTGTCGCCG 
TGGAGCGAGC TGGAATTCCA GTTTCCTGAT GACAAAGACC CAGTGTGGGA ATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_766244.4
CDS	376..1632
Translation	MSLLDCFCASRTRVESLRPEKQSETSIHQYLVDESAISRPPPSARASEVICSTDVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTVKITNLESCTEERLKALQRAVILSHFFQHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPDGMSETLIRNILFGAVQGLNYLHQNGCIHRSFKASHILISGDGLVTLSGLSHLHSLLKHGQRHRAVFDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDVSIFPQSDSRMRNSQSGVDSGIGESVLVSTGTHTVNSDRLHTPSTKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILPLLPPAYNRPSASLQPVSPWSELEFQFPDDKDPVWEF

Target ORF information:

RefSeq Version	NM_172656.5
Organism	Mus musculus(House mouse)
Definition	Mus musculus STE20-related kinase adaptor beta (Stradb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172656.5

ORF Insert Sequence:

ATGTCTCTTT TGGATTGTTT CTGTGCTTCA CGAACACGAG TCGAATCACT CAGACCCGAA 
AAACAGTCTG AAACCAGTAT CCATCAGTAC TTGGTTGATG AGTCAGCCAT TTCCCGGCCC 
CCTCCGTCTG CTAGAGCCAG TGAGGTGATC TGCTCCACTG ACGTGTCTCA CTATGAACTG 
CAAGTGGAGA TAGGAAGAGG GTTTGACAAC TTGACCTCTG TTCATCTTGC ACGGCACACT 
CCTACAGGAA CACTGGTAAC TGTAAAGATT ACAAACCTGG AAAGCTGCAC TGAAGAACGT 
CTGAAAGCTT TACAGAGAGC AGTGATTCTA TCTCACTTTT TCCAACATCC CAATATTACA 
ACTTATTGGA CAGTGTTCAC TGTTGGCAGC TGGCTTTGGG TTATTTCTCC ATTTATGGCC 
TACGGTTCAG CAAGTCAGCT CCTAAGGACC TACTTTCCTG ATGGAATGAG TGAGACTTTA 
ATAAGAAACA TTCTCTTTGG AGCAGTACAA GGGTTGAACT ATCTGCACCA AAATGGCTGT 
ATCCATAGGA GTTTTAAAGC CAGCCATATC CTCATTTCTG GTGATGGCCT GGTGACCCTC 
TCTGGCCTGT CCCACCTGCA TAGTTTGCTT AAGCACGGAC AAAGGCATAG GGCTGTGTTT 
GATTTCCCAC AGTTCAGCAC ATCAGTGCAG CCGTGGCTGA GTCCAGAACT ACTGAGACAG 
GATTTACATG GATATAATGT GAAGTCAGAT ATTTACAGTG TTGGGATCAC AGCCTGTGAA 
TTGGCCAGCG GGCAGGTACC TTTCCAGGAC ATGCATAGGA CTCAGATGCT ATTACAGAAA 
CTGAAAGGTC CTCCGTATAG CCCACTGGAT GTCAGTATTT TTCCTCAGTC AGACTCTAGA 
ATGAGAAATT CCCAGTCAGG AGTAGACTCT GGGATTGGAG AGAGTGTGCT TGTCTCCACT 
GGAACTCACA CAGTCAATAG TGACCGGCTC CATACGCCAT CCACAAAGAC GTTCTCTCCT 
GCCTTTTTTA GCTTGGTGCA GCTGTGTTTG CAGCAAGATC CTGAGAAAAG GCCATCAGCA 
AGCAGTTTGT TGTCCCATGT ATTCTTCAAG CAGATGAAAG AAGAAAGCCA GGATTCCATA 
CTTCCCCTGT TGCCACCTGC TTATAACAGG CCATCAGCGT CACTGCAGCC AGTGTCGCCG 
TGGAGCGAGC TGGAATTCCA GTTTCCTGAT GACAAAGACC CAGTGTGGGA ATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stradb ( NM_172656.6 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_766244.4 Mus musculus STE20-related kinase adaptor beta (Stradb), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu03835
Clone ID Related Accession (Same CDS sequence)	NM_172656.5 , NM_172656.6
Accession Version	NM_172656.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569340800000
Organism	Mus musculus(house mouse)
Product	STE20-related kinase adapter protein beta
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK140272.1, AK080096.1 and AI643873.1. On Oct 27, 2017 this sequence version replaced NM_172656.5. ##Evidence-Data-START## Transcript exon combination :: BC037003.1, AK046790.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTCTTT TGGATTGTTT CTGTGCTTCA CGAACACGAG TCGAATCACT CAGACCCGAA 
AAACAGTCTG AAACCAGTAT CCATCAGTAC TTGGTTGATG AGTCAGCCAT TTCCCGGCCC 
CCTCCGTCTG CTAGAGCCAG TGAGGTGATC TGCTCCACTG ACGTGTCTCA CTATGAACTG 
CAAGTGGAGA TAGGAAGAGG GTTTGACAAC TTGACCTCTG TTCATCTTGC ACGGCACACT 
CCTACAGGAA CACTGGTAAC TGTAAAGATT ACAAACCTGG AAAGCTGCAC TGAAGAACGT 
CTGAAAGCTT TACAGAGAGC AGTGATTCTA TCTCACTTTT TCCAACATCC CAATATTACA 
ACTTATTGGA CAGTGTTCAC TGTTGGCAGC TGGCTTTGGG TTATTTCTCC ATTTATGGCC 
TACGGTTCAG CAAGTCAGCT CCTAAGGACC TACTTTCCTG ATGGAATGAG TGAGACTTTA 
ATAAGAAACA TTCTCTTTGG AGCAGTACAA GGGTTGAACT ATCTGCACCA AAATGGCTGT 
ATCCATAGGA GTTTTAAAGC CAGCCATATC CTCATTTCTG GTGATGGCCT GGTGACCCTC 
TCTGGCCTGT CCCACCTGCA TAGTTTGCTT AAGCACGGAC AAAGGCATAG GGCTGTGTTT 
GATTTCCCAC AGTTCAGCAC ATCAGTGCAG CCGTGGCTGA GTCCAGAACT ACTGAGACAG 
GATTTACATG GATATAATGT GAAGTCAGAT ATTTACAGTG TTGGGATCAC AGCCTGTGAA 
TTGGCCAGCG GGCAGGTACC TTTCCAGGAC ATGCATAGGA CTCAGATGCT ATTACAGAAA 
CTGAAAGGTC CTCCGTATAG CCCACTGGAT GTCAGTATTT TTCCTCAGTC AGACTCTAGA 
ATGAGAAATT CCCAGTCAGG AGTAGACTCT GGGATTGGAG AGAGTGTGCT TGTCTCCACT 
GGAACTCACA CAGTCAATAG TGACCGGCTC CATACGCCAT CCACAAAGAC GTTCTCTCCT 
GCCTTTTTTA GCTTGGTGCA GCTGTGTTTG CAGCAAGATC CTGAGAAAAG GCCATCAGCA 
AGCAGTTTGT TGTCCCATGT ATTCTTCAAG CAGATGAAAG AAGAAAGCCA GGATTCCATA 
CTTCCCCTGT TGCCACCTGC TTATAACAGG CCATCAGCGT CACTGCAGCC AGTGTCGCCG 
TGGAGCGAGC TGGAATTCCA GTTTCCTGAT GACAAAGACC CAGTGTGGGA ATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_766244.4
CDS	425..1681
Translation	MSLLDCFCASRTRVESLRPEKQSETSIHQYLVDESAISRPPPSARASEVICSTDVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTVKITNLESCTEERLKALQRAVILSHFFQHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPDGMSETLIRNILFGAVQGLNYLHQNGCIHRSFKASHILISGDGLVTLSGLSHLHSLLKHGQRHRAVFDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDVSIFPQSDSRMRNSQSGVDSGIGESVLVSTGTHTVNSDRLHTPSTKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILPLLPPAYNRPSASLQPVSPWSELEFQFPDDKDPVWEF

Target ORF information:

RefSeq Version	NM_172656.6
Organism	Mus musculus(house mouse)
Definition	Mus musculus STE20-related kinase adaptor beta (Stradb), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172656.6

ORF Insert Sequence:

ATGTCTCTTT TGGATTGTTT CTGTGCTTCA CGAACACGAG TCGAATCACT CAGACCCGAA 
AAACAGTCTG AAACCAGTAT CCATCAGTAC TTGGTTGATG AGTCAGCCAT TTCCCGGCCC 
CCTCCGTCTG CTAGAGCCAG TGAGGTGATC TGCTCCACTG ACGTGTCTCA CTATGAACTG 
CAAGTGGAGA TAGGAAGAGG GTTTGACAAC TTGACCTCTG TTCATCTTGC ACGGCACACT 
CCTACAGGAA CACTGGTAAC TGTAAAGATT ACAAACCTGG AAAGCTGCAC TGAAGAACGT 
CTGAAAGCTT TACAGAGAGC AGTGATTCTA TCTCACTTTT TCCAACATCC CAATATTACA 
ACTTATTGGA CAGTGTTCAC TGTTGGCAGC TGGCTTTGGG TTATTTCTCC ATTTATGGCC 
TACGGTTCAG CAAGTCAGCT CCTAAGGACC TACTTTCCTG ATGGAATGAG TGAGACTTTA 
ATAAGAAACA TTCTCTTTGG AGCAGTACAA GGGTTGAACT ATCTGCACCA AAATGGCTGT 
ATCCATAGGA GTTTTAAAGC CAGCCATATC CTCATTTCTG GTGATGGCCT GGTGACCCTC 
TCTGGCCTGT CCCACCTGCA TAGTTTGCTT AAGCACGGAC AAAGGCATAG GGCTGTGTTT 
GATTTCCCAC AGTTCAGCAC ATCAGTGCAG CCGTGGCTGA GTCCAGAACT ACTGAGACAG 
GATTTACATG GATATAATGT GAAGTCAGAT ATTTACAGTG TTGGGATCAC AGCCTGTGAA 
TTGGCCAGCG GGCAGGTACC TTTCCAGGAC ATGCATAGGA CTCAGATGCT ATTACAGAAA 
CTGAAAGGTC CTCCGTATAG CCCACTGGAT GTCAGTATTT TTCCTCAGTC AGACTCTAGA 
ATGAGAAATT CCCAGTCAGG AGTAGACTCT GGGATTGGAG AGAGTGTGCT TGTCTCCACT 
GGAACTCACA CAGTCAATAG TGACCGGCTC CATACGCCAT CCACAAAGAC GTTCTCTCCT 
GCCTTTTTTA GCTTGGTGCA GCTGTGTTTG CAGCAAGATC CTGAGAAAAG GCCATCAGCA 
AGCAGTTTGT TGTCCCATGT ATTCTTCAAG CAGATGAAAG AAGAAAGCCA GGATTCCATA 
CTTCCCCTGT TGCCACCTGC TTATAACAGG CCATCAGCGT CACTGCAGCC AGTGTCGCCG 
TGGAGCGAGC TGGAATTCCA GTTTCCTGAT GACAAAGACC CAGTGTGGGA ATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

STRAD pseudokinases regulate axogenesis and LKB1 stability.
Neural development95(2014 Mar)
Veleva-Rotse BO,Smart JL,Baas AF,Edmonds B,Zhao ZM,Brown A,Klug LR,Hansen K,Reilly G,Gardner AP,Subbiah K,Gaucher EA,Clevers H,Barnes AP

Characterization of the liver kinase B1-mouse protein-25 -Ste-20-related adaptor protein complex in adult mouse skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985)111(6)1622-8(2011 Dec)
Smith CD,Compton RA,Bowler JS,Kemp JT,Sudweeks SN,Thomson DM,Winder WW

Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling.
Genome biology10(10)R104(2009)
Ling KH,Hewitt CA,Beissbarth T,Hyde L,Banerjee K,Cheah PS,Cannon PZ,Hahn CN,Thomas PQ,Smyth GK,Tan SS,Thomas T,Scott HS

LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.
Cell129(3)549-63(2007 May)
Barnes AP,Lilley BN,Pan YA,Plummer LJ,Powell AW,Raines AN,Sanes JR,Polleux F

Identification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinase.
The Journal of biological chemistry278(15)13520-30(2003 Apr)
Nishigaki K,Thompson D,Yugawa T,Rulli K,Hanson C,Cmarik J,Gutkind JS,Teramoto H,Ruscetti S

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Stradb cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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