Tgm2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tgm2
Entrez Gene ID	21817
Full Name	transglutaminase 2, C polypeptide
Synonyms	G[a]h,TG2,TGase2,tTG,tTGas
General protein information	Preferred Names transglutaminase 2, C polypeptide Names protein-glutamine gamma-glutamyltransferase 2 C polypeptide TG(C) TGC TGase C TGase-2 protein-glutamine-gamma-glutamyltransferase tissue transglutaminase transglutaminase C transglutaminase-2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 H1\|2 78.72 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_009373.3	NP_033399.1	protein-glutamine gamma-glutamyltransferase 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TGM2	XP_001144553.2
Canis lupus familiaris (dog)	TGM2	XP_542991.4
Gallus gallus (chicken)	TGM2	NP_990779.1
Danio rerio (zebrafish)	tgm2b	NP_997821.2
Homo sapiens (human)	TGM2	NP_004604.2
Bos taurus (cattle)	TGM2	NP_803473.1
Rattus norvegicus (Norway rat)	Tgm2	NP_062259.2
Xenopus tropicalis (tropical clawed frog)	tgm2	NP_001123852.1
Mus musculus (house mouse)	Tgm2	NP_033399.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of Betamethasone-Regulated Target Genes and Cell Pathways in Fetal Rat Lung Mesenchymal Fibroblasts.
Seow BKL, McDougall ARA, Short KL, Wallace MJ, Hooper SB, Cole TJ
Endocrinology160(8)1868-1884(2019 08)

Contribution of tissue transglutaminase to the severity of hepatic fibrosis resulting from Schistosoma japonicum infection through the regulation of IL-33/ST2 expression.
Li ZY, Xiao L, Lin G, Tang J, Chen Y, Chen L, Li B, Wu M, Liu S, Huang C, Ferrandon D, Li Z
Parasites & vectors12(1)302(2019 Jun)

A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia.
Serrano RL, Yu W, Graham RM, Bryan RL, Terkeltaub R
PloS one14(4)e0212235(2019)

Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75.
D'Eletto M, Rossin F, Occhigrossi L, Farrace MG, Faccenda D, Desai R, Marchi S, Refolo G, Falasca L, Antonioli M, Ciccosanti F, Fimia GM, Pinton P, Campanella M, Piacentini M
Cell reports25(13)3573-3581.e4(2018 12)

Transglutaminase 2 Induces Deficits in Social Behavior in Mice.
Crider A, Davis T, Ahmed AO, Mei L, Pillai A
Neural plasticity20182019091(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tgm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tgm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu19696	NM_009373.3 Latest version!	Mus musculus transglutaminase 2, C polypeptide (Tgm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$398.30 $569.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tgm2 ( NM_009373.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033399.1 Mus musculus transglutaminase 2, C polypeptide (Tgm2), mRNA.

Price & Availability↑

CloneID	OMu19696
Clone ID Related Accession (Same CDS sequence)	NM_009373.3
Accession Version	NM_009373.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575648000000
Organism	Mus musculus(house mouse)
Product	protein-glutamine gamma-glutamyltransferase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL669824.13. On Nov 17, 2006 this sequence version replaced NM_009373.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK151776.1, AK152627.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164134 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGAGG AGCTGCTCCT GGAGAGGTGT GATTTGGAGA TTCAGGCCAA TGGCCGTGAC 
CACCACACGG CCGACCTATG CCAAGAGAAA CTGGTGCTGC GTCGTGGTCA GCGCTTCCGG 
CTGACTCTGT ACTTCGAGGG CCGTGGCTAC GAGGCCAGCG TGGACAGCCT CACGTTCGGT 
GCTGTGACCG GCCCAGATCC CAGTGAAGAG GCAGGGACCA AGGCCCGCTT CTCACTGTCT 
GACAATGTGG AGGAGGGATC TTGGTCAGCC TCAGTGCTGG ACCAACAGGA CAATGTCCTC 
TCGCTACAGC TCTGCACCCC AGCCAATGCT CCTATTGGCC TGTACCGTCT CAGCCTAGAG 
GCTTCTACTG GCTACCAGGG CTCCAGCTTT GTGCTGGGCC ACTTCATCCT GCTCTACAAT 
GCCTGGTGCC CAGCCGATGA TGTGTACCTA GACTCAGAGG AGGAGCGACG GGAATATGTC 
CTTACGCAAC AGGGCTTCAT CTACCAAGGC TCTGTCAAGT TCATCAAGAG TGTGCCTTGG 
AACTTTGGGC AGTTCGAGGA TGGAATCCTG GATACCTGCC TGATGCTCTT GGATATGAAC 
CCCAAGTTCC TGAAGAACCG TAGTCGGGAC TGCTCACGCC GCAGCAGTCC CATCTATGTG 
GGCCGCGTGG TGAGCGCCAT GGTCAACTGC AATGATGACC AGGGTGTGCT TCTGGGCCGC 
TGGGACAACA ACTATGGGGA TGGTATCAGT CCCATGGCCT GGATTGGCAG TGTGGACATT 
CTGCGGCGCT GGAAGGAACA CGGCTGTCAG CAAGTGAAGT ACGGGCAGTG CTGGGTGTTT 
GCAGCGGTGG CCTGCACAGT GCTGCGGTGC CTCGGCATCC CTACCAGAGT GGTGACCAAC 
TACAACTCCG CCCACGACCA GAACAGCAAC CTGCTCATCG AGTACTTCCG AAATGAGTTC 
GGGGAGCTGG AGAGCAACAA GAGCGAGATG ATCTGGAACT TCCACTGCTG GGTGGAGTCC 
TGGATGACCA GGCCAGACCT ACAGCCGGGC TATGAGGGGT GGCAGGCCAT TGACCCCACA 
CCACAGGAGA AGAGCGAAGG GACATACTGT TGTGGCCCAG TCTCAGTGCG AGCCATCAAG 
GAGGGAGACC TGAGTACCAA GTATGATGCA CCCTTCGTGT TTGCCGAGGT CAACGCTGAT 
GTGGTGGACT GGATCCGGCA GGAAGATGGG TCTGTGCTCA AATCCATCAA CCGTTCCTTG 
GTCGTGGGGC AGAAGATCAG CACTAAGAGT GTGGGCCGTG ATGACCGGGA GGACATCACC 
CATACCTACA AGTACCCAGA GGGGTCACCC GAGGAGAGGG AAGTCTTCAC CAAGGCCAAC 
CACCTGAACA AACTGGCAGA GAAAGAGGAG ACAGGGGTGG CCATGCGCAT CCGAGTGGGG 
GACAGTATGA GCATGGGCAA CGACTTCGAC GTGTTTGCCC ACATCGGCAA CGACACCTCG 
GAGACTCGAG AGTGTCGTCT CCTGCTCTGT GCCCGCACTG TCAGCTACAA CGGGGTGCTG 
GGGCCCGAGT GTGGCACTGA GGACATCAAC CTGACCCTGG ATCCCTACTC TGAGAACAGC 
ATCCCACTTC GAATCCTCTA CGAGAAGTAC AGCGGGTGCC TGACAGAGTC AAACCTCATC 
AAGGTGCGGG GCCTTCTCAT CGAACCAGCT GCCAACAGCT ACCTGCTGGC TGAGAGAGAT 
CTCTACCTGG AGAATCCCGA AATCAAGATC CGGGTCCTGG GAGAACCCAA GCAAAACCGC 
AAACTGGTGG CTGAGGTGTC CCTGAAGAAC CCACTTTCCG ATCCCCTGTA TGACTGCATC 
TTCACTGTGG AGGGGGCTGG CCTGACCAAG GAGCAGAAGT CTGTGGAAGT CTCAGACCCG 
GTGCCAGCGG GCGATTTGGT CAAGGCACGG GTCGACCTGT TCCCGACTGA TATTGGCCTC 
CACAAGCTGG TGGTGAACTT CCAGTGTGAC AAGCTGAAGT CGGTGAAGGG TTACCGGAAT 
GTTATCATCG GCCCGGCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033399.1
CDS	93..2153
Translation	MAEELLLERCDLEIQANGRDHHTADLCQEKLVLRRGQRFRLTLYFEGRGYEASVDSLTFGAVTGPDPSEEAGTKARFSLSDNVEEGSWSASVLDQQDNVLSLQLCTPANAPIGLYRLSLEASTGYQGSSFVLGHFILLYNAWCPADDVYLDSEEERREYVLTQQGFIYQGSVKFIKSVPWNFGQFEDGILDTCLMLLDMNPKFLKNRSRDCSRRSSPIYVGRVVSAMVNCNDDQGVLLGRWDNNYGDGISPMAWIGSVDILRRWKEHGCQQVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEFGELESNKSEMIWNFHCWVESWMTRPDLQPGYEGWQAIDPTPQEKSEGTYCCGPVSVRAIKEGDLSTKYDAPFVFAEVNADVVDWIRQEDGSVLKSINRSLVVGQKISTKSVGRDDREDITHTYKYPEGSPEEREVFTKANHLNKLAEKEETGVAMRIRVGDSMSMGNDFDVFAHIGNDTSETRECRLLLCARTVSYNGVLGPECGTEDINLTLDPYSENSIPLRILYEKYSGCLTESNLIKVRGLLIEPAANSYLLAERDLYLENPEIKIRVLGEPKQNRKLVAEVSLKNPLSDPLYDCIFTVEGAGLTKEQKSVEVSDPVPAGDLVKARVDLFPTDIGLHKLVVNFQCDKLKSVKGYRNVIIGPA

Target ORF information:

RefSeq Version	NM_009373.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus transglutaminase 2, C polypeptide (Tgm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009373.3

ORF Insert Sequence:

ATGGCAGAGG AGCTGCTCCT GGAGAGGTGT GATTTGGAGA TTCAGGCCAA TGGCCGTGAC 
CACCACACGG CCGACCTATG CCAAGAGAAA CTGGTGCTGC GTCGTGGTCA GCGCTTCCGG 
CTGACTCTGT ACTTCGAGGG CCGTGGCTAC GAGGCCAGCG TGGACAGCCT CACGTTCGGT 
GCTGTGACCG GCCCAGATCC CAGTGAAGAG GCAGGGACCA AGGCCCGCTT CTCACTGTCT 
GACAATGTGG AGGAGGGATC TTGGTCAGCC TCAGTGCTGG ACCAACAGGA CAATGTCCTC 
TCGCTACAGC TCTGCACCCC AGCCAATGCT CCTATTGGCC TGTACCGTCT CAGCCTAGAG 
GCTTCTACTG GCTACCAGGG CTCCAGCTTT GTGCTGGGCC ACTTCATCCT GCTCTACAAT 
GCCTGGTGCC CAGCCGATGA TGTGTACCTA GACTCAGAGG AGGAGCGACG GGAATATGTC 
CTTACGCAAC AGGGCTTCAT CTACCAAGGC TCTGTCAAGT TCATCAAGAG TGTGCCTTGG 
AACTTTGGGC AGTTCGAGGA TGGAATCCTG GATACCTGCC TGATGCTCTT GGATATGAAC 
CCCAAGTTCC TGAAGAACCG TAGTCGGGAC TGCTCACGCC GCAGCAGTCC CATCTATGTG 
GGCCGCGTGG TGAGCGCCAT GGTCAACTGC AATGATGACC AGGGTGTGCT TCTGGGCCGC 
TGGGACAACA ACTATGGGGA TGGTATCAGT CCCATGGCCT GGATTGGCAG TGTGGACATT 
CTGCGGCGCT GGAAGGAACA CGGCTGTCAG CAAGTGAAGT ACGGGCAGTG CTGGGTGTTT 
GCAGCGGTGG CCTGCACAGT GCTGCGGTGC CTCGGCATCC CTACCAGAGT GGTGACCAAC 
TACAACTCCG CCCACGACCA GAACAGCAAC CTGCTCATCG AGTACTTCCG AAATGAGTTC 
GGGGAGCTGG AGAGCAACAA GAGCGAGATG ATCTGGAACT TCCACTGCTG GGTGGAGTCC 
TGGATGACCA GGCCAGACCT ACAGCCGGGC TATGAGGGGT GGCAGGCCAT TGACCCCACA 
CCACAGGAGA AGAGCGAAGG GACATACTGT TGTGGCCCAG TCTCAGTGCG AGCCATCAAG 
GAGGGAGACC TGAGTACCAA GTATGATGCA CCCTTCGTGT TTGCCGAGGT CAACGCTGAT 
GTGGTGGACT GGATCCGGCA GGAAGATGGG TCTGTGCTCA AATCCATCAA CCGTTCCTTG 
GTCGTGGGGC AGAAGATCAG CACTAAGAGT GTGGGCCGTG ATGACCGGGA GGACATCACC 
CATACCTACA AGTACCCAGA GGGGTCACCC GAGGAGAGGG AAGTCTTCAC CAAGGCCAAC 
CACCTGAACA AACTGGCAGA GAAAGAGGAG ACAGGGGTGG CCATGCGCAT CCGAGTGGGG 
GACAGTATGA GCATGGGCAA CGACTTCGAC GTGTTTGCCC ACATCGGCAA CGACACCTCG 
GAGACTCGAG AGTGTCGTCT CCTGCTCTGT GCCCGCACTG TCAGCTACAA CGGGGTGCTG 
GGGCCCGAGT GTGGCACTGA GGACATCAAC CTGACCCTGG ATCCCTACTC TGAGAACAGC 
ATCCCACTTC GAATCCTCTA CGAGAAGTAC AGCGGGTGCC TGACAGAGTC AAACCTCATC 
AAGGTGCGGG GCCTTCTCAT CGAACCAGCT GCCAACAGCT ACCTGCTGGC TGAGAGAGAT 
CTCTACCTGG AGAATCCCGA AATCAAGATC CGGGTCCTGG GAGAACCCAA GCAAAACCGC 
AAACTGGTGG CTGAGGTGTC CCTGAAGAAC CCACTTTCCG ATCCCCTGTA TGACTGCATC 
TTCACTGTGG AGGGGGCTGG CCTGACCAAG GAGCAGAAGT CTGTGGAAGT CTCAGACCCG 
GTGCCAGCGG GCGATTTGGT CAAGGCACGG GTCGACCTGT TCCCGACTGA TATTGGCCTC 
CACAAGCTGG TGGTGAACTT CCAGTGTGAC AAGCTGAAGT CGGTGAAGGG TTACCGGAAT 
GTTATCATCG GCCCGGCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of Betamethasone-Regulated Target Genes and Cell Pathways in Fetal Rat Lung Mesenchymal Fibroblasts.
Endocrinology160(8)1868-1884(2019 08)
Seow BKL,McDougall ARA,Short KL,Wallace MJ,Hooper SB,Cole TJ

Contribution of tissue transglutaminase to the severity of hepatic fibrosis resulting from Schistosoma japonicum infection through the regulation of IL-33/ST2 expression.
Parasites & vectors12(1)302(2019 Jun)
Li ZY,Xiao L,Lin G,Tang J,Chen Y,Chen L,Li B,Wu M,Liu S,Huang C,Ferrandon D,Li Z

A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia.
PloS one14(4)e0212235(2019)
Serrano RL,Yu W,Graham RM,Bryan RL,Terkeltaub R

Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75.
Cell reports25(13)3573-3581.e4(2018 12)
D'Eletto M,Rossin F,Occhigrossi L,Farrace MG,Faccenda D,Desai R,Marchi S,Refolo G,Falasca L,Antonioli M,Ciccosanti F,Fimia GM,Pinton P,Campanella M,Piacentini M

Transglutaminase 2 Induces Deficits in Social Behavior in Mice.
Neural plasticity20182019091(2018)
Crider A,Davis T,Ahmed AO,Mei L,Pillai A

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Tgm2 cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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