Kif5b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kif5b
Entrez Gene ID	16573
Full Name	kinesin family member 5B
Synonyms	AL022807,Khc,Khcs,Kns1,Ukhc
General protein information	Preferred Names kinesin family member 5B Names kinesin-1 heavy chain conventional kinesin heavy chain kinesin heavy chain member 5B, ubiquitous ubiquitous kinesin heavy chain
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18 A1\|18 4.46 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008448.3	NP_032474.2	kinesin-1 heavy chain

Pathways from BioSystems

Homologies

Homo sapiens (human)	KIF5B	NP_004512.1
Bos taurus (cattle)	KIF5B	NP_001179294.1
Neurospora crassa	NCU09730	XP_964432.2
Danio rerio (zebrafish)	kif5ba	XP_005171465.1
Caenorhabditis elegans (roundworm)	unc-116	NP_498842.1
Canis lupus familiaris (dog)	KIF5B	XP_003638926.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000561	XP_310522.2
Macaca mulatta (Rhesus monkey)	KIF5B	XP_002805653.1
Drosophila melanogaster (fruit fly)	Khc	NP_476590.1
Magnaporthe oryzae (rice blast fungus)	MGG_01757	XP_003714755.1
Pan troglodytes (chimpanzee)	KIF5B	XP_507730.2
Mus musculus (house mouse)	Kif5b	NP_032474.2
Rattus norvegicus (Norway rat)	Kif5b	NP_476550.1
Gallus gallus (chicken)	KIF5B	XP_004939228.1
Danio rerio (zebrafish)	kif5bb	XP_002664065.1
Xenopus tropicalis (tropical clawed frog)	kif5b	NP_001122126.1

Gene Ontology
Bibliography

Related articles in PubMed

Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors.
Cromberg LE, Saez TMM, Otero MG, Tomasella E, Alloatti M, Damianich A, Pozo Devoto V, Ferrario J, Gelman D, Rubinstein M, Falzone TL
Journal of neurochemistry149(3)362-380(2019 May)

SNAP23-Kif5 complex controls mGlu1 receptor trafficking.
Raynaud F, Homburger V, Seveno M, Vigy O, Moutin E, Fagni L, Perroy J
Journal of molecular cell biology10(5)423-436(2018 10)

Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.
DuRaine G, Wisner TW, Howard P, Johnson DC
Journal of virology92(20)(2018 10)

Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration.
Latremoliere A, Cheng L, DeLisle M, Wu C, Chew S, Hutchinson EB, Sheridan A, Alexandre C, Latremoliere F, Sheu SH, Golidy S, Omura T, Huebner EA, Fan Y, Whitman MC, Nguyen E, Hermawan C, Pierpaoli C, Tischfield MA, Woolf CJ, Engle EC
Cell reports24(7)1865-1879.e9(2018 08)

Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes.
Habtemichael EN, Li DT, Alcázar-Román A, Westergaard XO, Li M, Petersen MC, Li H, DeVries SG, Li E, Julca-Zevallos O, Wolenski JS, Bogan JS
The Journal of biological chemistry293(27)10466-10486(2018 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kif5b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kif5b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu16208	NM_008448.3 Latest version!	Mus musculus kinesin family member 5B (Kif5b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$566.30 $809.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kif5b ( NM_008448.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032474.2 Mus musculus kinesin family member 5B (Kif5b), mRNA.

Price & Availability↑

CloneID	OMu16208
Clone ID Related Accession (Same CDS sequence)	NM_008448.3
Accession Version	NM_008448.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2892bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	kinesin-1 heavy chain
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI788274.1, BC090841.1, AK014590.1, AV316286.1 and AC113003.9. On Jan 13, 2010 this sequence version replaced NM_008448.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.74537.1, SRR1660813.80310.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACC CGGCGGAGTG CAACATCAAA GTGATGTGTC GCTTCAGACC TCTCAACGAA 
TCTGAAGTGA ACCGCGGCGA TAAGTACGTC GCCAAATTCC AGGGAGAAGA CACGGTGATG 
ATCGCGTCCA AGCCTTATGC CTTTGATCGT GTGTTCCAGT CAAGCACATC TCAAGAGCAA 
GTATACAACG ACTGTGCAAA AAAGATTGTT AAAGATGTTC TTGAGGGCTA TAATGGAACA 
ATATTTGCAT ATGGACAAAC ATCATCTGGG AAGACCCACA CGATGGAGGG TAAACTTCAT 
GATCCAGAAG GCATGGGAAT TATTCCAAGA ATAGTGCAAG ATATTTTTAA TTATATTTAC 
TCCATGGATG AAAATTTGGA ATTTCATATT AAGGTTTCAT ATTTTGAAAT ATATTTGGAT 
AAGATAAGGG ACTTGTTAGA TGTTTCAAAG ACTAACCTTT CAGTCCATGA AGACAAAAAC 
CGTGTTCCCT ATGTAAAGGG GTGCACAGAA CGTTTCGTGT GTAGTCCAGA TGAAGTCATG 
GATACCATAG ATGAAGGGAA ATCCAACAGA CATGTCGCAG TTACAAATAT GAATGAACAT 
AGCTCTAGGA GTCACAGCAT ATTTCTTATT AATGTAAAAC AAGAGAATAC ACAAACGGAA 
CAGAAACTCA GTGGAAAGCT TTATCTGGTT GATTTAGCTG GCAGTGAGAA GGTTAGTAAG 
ACTGGGGCTG AAGGTGCTGT GCTGGATGAA GCTAAGAACA TCAACAAGTC ACTTTCTGCA 
CTTGGAAATG TCATTTCTGC TTTGGCAGAG GGCAGTACCT ATGTTCCTTA TCGAGATAGT 
AAAATGACCA GAATTCTTCA AGATTCATTA GGTGGCAACT GTAGGACCAC TATTGTCATA 
TGCTGCTCTC CATCATCATA CAATGAGTCT GAGACAAAGT CAACACTCCT CTTTGGTCAA 
AGGGCCAAAA CAATTAAGAA CACAGTCTGT GTCAATGTAG AGTTAACTGC GGAGCAGTGG 
AAAAAGAAGT ATGAAAAAGA AAAGGAAAAA AATAAAACTC TACGGAACAC TATTCAGTGG 
CTGGAAAACG AGCTAAACCG TTGGCGTAAC GGGGAGACAG TGCCTATTGA TGAGCAGTTT 
GACAAAGAGA AAGCTAATTT GGAAGCCTTC ACAGCGGATA AAGATATTGC TATTACCAGT 
GATAAACCAG CTGCTGCAGT CGGAATGGCT GGTAGTTTTA CCGATGCTGA AAGAAGAAAG 
TGTGAAGAAG AACTTGCTAA ATTGTATAAA CAACTTGATG ACAAGGATGA AGAGATTAAC 
CAACAAAGCC AATTGGTAGA GAAATTGAAG ACACAAATGC TGGATCAGGA AGAGCTTCTG 
GCATCAACCA GAAGGGATCA AGATAATATG CAAGCTGAAC TGAATCGCCT CCAAGCAGAA 
AATGATGCTT CTAAAGAAGA AGTCAAAGAA GTTTTACAGG CCTTAGAGGA ACTGGCTGTT 
AATTATGATC AGAAGTCTCA GGAAGTTGAA GACAAAACAA AGGAATATGA ATTGCTTAGT 
GATGAATTGA ATCAAAAATC TGCAACTTTA GCAAGTATTG ATGCTGAGCT TCAGAAGCTG 
AAGGAAATGA CCAACCACCA GAAGAAACGA GCAGCTGAAA TGATGGCATC ATTATTAAAA 
GACCTTGCAG AAATAGGAAT TGCTGTGGGG AATAACGATG TGAAGCAACC AGAAGGAACT 
GGTATGATAG ATGAAGAGTT TACTGTTGCA AGACTCTACA TTAGCAAAAT GAAATCAGAA 
GTAAAGACCA TGGTGAAACG CTGCAAACAG CTAGAAAGCA CACAGACTGA GAGCAACAAA 
AAAATGGAAG AAAATGAGAA AGAGTTAGCA GCATGCCAGC TTCGGATCTC CCAACATGAA 
GCCAAAATCA AGTCACTGAC TGAGTACCTT CAGAATGTAG AACAAAAGAA GAGGCAGCTG 
GAGGAGTCTG TTGATTCCCT TGGTGAGGAG CTAGTCCAAC TCCGAGCACA AGAGAAAGTC 
CATGAAATGG AAAAAGAGCA CTTGAACAAG GTTCAGACTG CAAATGAAGT CAAGCAAGCT 
GTTGAGCAGC AGATCCAGAG TCACAGAGAA ACCCACCAAA AACAAATCAG TAGTTTGCGA 
GATGAAGTGG AGGCAAAGGA AAAGCTAATC ACTGACCTCC AAGACCAAAA CCAGAAGATG 
GTGTTGGAGC AGGAACGGCT AAGGGTGGAG CATGAGAGGC TGAAGGCTAC AGACCAAGAG 
AAGAGCAGGA AGCTGCACGA GCTCACGGTT ATGCAAGACA GACGAGAACA AGCAAGACAA 
GACTTGAAGG GTTTGGAGGA GACCGTGGCA AAAGAACTTC AGACTTTACA CAACCTGCGT 
AAGCTCTTTG TTCAGGACTT GGCTACCAGG GTGAAAAAGA GCGCCGAGGT CGACTCTGAC 
GACACTGGCG GCAGTGCTGC ACAGAAGCAG AAAATCTCCT TCCTTGAAAA CAACCTTGAA 
CAGCTCACCA AAGTGCACAA GCAGTTGGTA CGCGATAATG CAGATCTTCG CTGTGAGCTT 
CCTAAGTTAG AGAAACGGCT TAGAGCTACT GCAGAAAGAG TGAAAGCTTT GGAGTCAGCC 
CTGAAAGAAG CCAAAGAAAA TGCATCTCGA GACCGTAAAC GCTATCAGCA AGAAGTAGAC 
CGGATAAAGG AAGCAGTCAG GTCAAAGAAC ATGGCCAGAA GGGGACATTC TGCCCAGATT 
GCAAAGCCGA TCCGTCCTGG ACAGCATCCA GCGGCCTCGC CAACTCACCC GGGCACAGTT 
CGTGGAGGAG GCTCATTTGT TCAGAACAAC CAGCCAGTGG GGCTTCGTGG TGGTGGAGGC 
AAGCAGTCGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032474.2
CDS	418..3309
Translation	MADPAECNIKVMCRFRPLNESEVNRGDKYVAKFQGEDTVMIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKTLRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTADKDIAITSDKPAAAVGMAGSFTDAERRKCEEELAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDSLGEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKEKLITDLQDQNQKMVLEQERLRVEHERLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEVDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHPGTVRGGGSFVQNNQPVGLRGGGGKQS

Target ORF information:

RefSeq Version	NM_008448.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus kinesin family member 5B (Kif5b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008448.3

ORF Insert Sequence:

ATGGCGGACC CGGCGGAGTG CAACATCAAA GTGATGTGTC GCTTCAGACC TCTCAACGAA 
TCTGAAGTGA ACCGCGGCGA TAAGTACGTC GCCAAATTCC AGGGAGAAGA CACGGTGATG 
ATCGCGTCCA AGCCTTATGC CTTTGATCGT GTGTTCCAGT CAAGCACATC TCAAGAGCAA 
GTATACAACG ACTGTGCAAA AAAGATTGTT AAAGATGTTC TTGAGGGCTA TAATGGAACA 
ATATTTGCAT ATGGACAAAC ATCATCTGGG AAGACCCACA CGATGGAGGG TAAACTTCAT 
GATCCAGAAG GCATGGGAAT TATTCCAAGA ATAGTGCAAG ATATTTTTAA TTATATTTAC 
TCCATGGATG AAAATTTGGA ATTTCATATT AAGGTTTCAT ATTTTGAAAT ATATTTGGAT 
AAGATAAGGG ACTTGTTAGA TGTTTCAAAG ACTAACCTTT CAGTCCATGA AGACAAAAAC 
CGTGTTCCCT ATGTAAAGGG GTGCACAGAA CGTTTCGTGT GTAGTCCAGA TGAAGTCATG 
GATACCATAG ATGAAGGGAA ATCCAACAGA CATGTCGCAG TTACAAATAT GAATGAACAT 
AGCTCTAGGA GTCACAGCAT ATTTCTTATT AATGTAAAAC AAGAGAATAC ACAAACGGAA 
CAGAAACTCA GTGGAAAGCT TTATCTGGTT GATTTAGCTG GCAGTGAGAA GGTTAGTAAG 
ACTGGGGCTG AAGGTGCTGT GCTGGATGAA GCTAAGAACA TCAACAAGTC ACTTTCTGCA 
CTTGGAAATG TCATTTCTGC TTTGGCAGAG GGCAGTACCT ATGTTCCTTA TCGAGATAGT 
AAAATGACCA GAATTCTTCA AGATTCATTA GGTGGCAACT GTAGGACCAC TATTGTCATA 
TGCTGCTCTC CATCATCATA CAATGAGTCT GAGACAAAGT CAACACTCCT CTTTGGTCAA 
AGGGCCAAAA CAATTAAGAA CACAGTCTGT GTCAATGTAG AGTTAACTGC GGAGCAGTGG 
AAAAAGAAGT ATGAAAAAGA AAAGGAAAAA AATAAAACTC TACGGAACAC TATTCAGTGG 
CTGGAAAACG AGCTAAACCG TTGGCGTAAC GGGGAGACAG TGCCTATTGA TGAGCAGTTT 
GACAAAGAGA AAGCTAATTT GGAAGCCTTC ACAGCGGATA AAGATATTGC TATTACCAGT 
GATAAACCAG CTGCTGCAGT CGGAATGGCT GGTAGTTTTA CCGATGCTGA AAGAAGAAAG 
TGTGAAGAAG AACTTGCTAA ATTGTATAAA CAACTTGATG ACAAGGATGA AGAGATTAAC 
CAACAAAGCC AATTGGTAGA GAAATTGAAG ACACAAATGC TGGATCAGGA AGAGCTTCTG 
GCATCAACCA GAAGGGATCA AGATAATATG CAAGCTGAAC TGAATCGCCT CCAAGCAGAA 
AATGATGCTT CTAAAGAAGA AGTCAAAGAA GTTTTACAGG CCTTAGAGGA ACTGGCTGTT 
AATTATGATC AGAAGTCTCA GGAAGTTGAA GACAAAACAA AGGAATATGA ATTGCTTAGT 
GATGAATTGA ATCAAAAATC TGCAACTTTA GCAAGTATTG ATGCTGAGCT TCAGAAGCTG 
AAGGAAATGA CCAACCACCA GAAGAAACGA GCAGCTGAAA TGATGGCATC ATTATTAAAA 
GACCTTGCAG AAATAGGAAT TGCTGTGGGG AATAACGATG TGAAGCAACC AGAAGGAACT 
GGTATGATAG ATGAAGAGTT TACTGTTGCA AGACTCTACA TTAGCAAAAT GAAATCAGAA 
GTAAAGACCA TGGTGAAACG CTGCAAACAG CTAGAAAGCA CACAGACTGA GAGCAACAAA 
AAAATGGAAG AAAATGAGAA AGAGTTAGCA GCATGCCAGC TTCGGATCTC CCAACATGAA 
GCCAAAATCA AGTCACTGAC TGAGTACCTT CAGAATGTAG AACAAAAGAA GAGGCAGCTG 
GAGGAGTCTG TTGATTCCCT TGGTGAGGAG CTAGTCCAAC TCCGAGCACA AGAGAAAGTC 
CATGAAATGG AAAAAGAGCA CTTGAACAAG GTTCAGACTG CAAATGAAGT CAAGCAAGCT 
GTTGAGCAGC AGATCCAGAG TCACAGAGAA ACCCACCAAA AACAAATCAG TAGTTTGCGA 
GATGAAGTGG AGGCAAAGGA AAAGCTAATC ACTGACCTCC AAGACCAAAA CCAGAAGATG 
GTGTTGGAGC AGGAACGGCT AAGGGTGGAG CATGAGAGGC TGAAGGCTAC AGACCAAGAG 
AAGAGCAGGA AGCTGCACGA GCTCACGGTT ATGCAAGACA GACGAGAACA AGCAAGACAA 
GACTTGAAGG GTTTGGAGGA GACCGTGGCA AAAGAACTTC AGACTTTACA CAACCTGCGT 
AAGCTCTTTG TTCAGGACTT GGCTACCAGG GTGAAAAAGA GCGCCGAGGT CGACTCTGAC 
GACACTGGCG GCAGTGCTGC ACAGAAGCAG AAAATCTCCT TCCTTGAAAA CAACCTTGAA 
CAGCTCACCA AAGTGCACAA GCAGTTGGTA CGCGATAATG CAGATCTTCG CTGTGAGCTT 
CCTAAGTTAG AGAAACGGCT TAGAGCTACT GCAGAAAGAG TGAAAGCTTT GGAGTCAGCC 
CTGAAAGAAG CCAAAGAAAA TGCATCTCGA GACCGTAAAC GCTATCAGCA AGAAGTAGAC 
CGGATAAAGG AAGCAGTCAG GTCAAAGAAC ATGGCCAGAA GGGGACATTC TGCCCAGATT 
GCAAAGCCGA TCCGTCCTGG ACAGCATCCA GCGGCCTCGC CAACTCACCC GGGCACAGTT 
CGTGGAGGAG GCTCATTTGT TCAGAACAAC CAGCCAGTGG GGCTTCGTGG TGGTGGAGGC 
AAGCAGTCGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors.
Journal of neurochemistry149(3)362-380(2019 May)
Cromberg LE,Saez TMM,Otero MG,Tomasella E,Alloatti M,Damianich A,Pozo Devoto V,Ferrario J,Gelman D,Rubinstein M,Falzone TL

SNAP23-Kif5 complex controls mGlu1 receptor trafficking.
Journal of molecular cell biology10(5)423-436(2018 10)
Raynaud F,Homburger V,Seveno M,Vigy O,Moutin E,Fagni L,Perroy J

Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.
Journal of virology92(20)(2018 10)
DuRaine G,Wisner TW,Howard P,Johnson DC

Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration.
Cell reports24(7)1865-1879.e9(2018 08)
Latremoliere A,Cheng L,DeLisle M,Wu C,Chew S,Hutchinson EB,Sheridan A,Alexandre C,Latremoliere F,Sheu SH,Golidy S,Omura T,Huebner EA,Fan Y,Whitman MC,Nguyen E,Hermawan C,Pierpaoli C,Tischfield MA,Woolf CJ,Engle EC

Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes.
The Journal of biological chemistry293(27)10466-10486(2018 07)
Habtemichael EN,Li DT,Alcázar-Román A,Westergaard XO,Li M,Petersen MC,Li H,DeVries SG,Li E,Julca-Zevallos O,Wolenski JS,Bogan JS

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Kif5b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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