Irak1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Irak1
Entrez Gene ID	16179
Full Name	interleukin-1 receptor-associated kinase 1
Synonyms	AA408924,IRAK,IRAK-1,IRAK1-S,IRAK1b,Il1rak,Plpk,mPLK
General protein information	Preferred Names interleukin-1 receptor-associated kinase 1 Names interleukin-1 receptor-associated kinase 1 interleukin-1 receptor-associated kinase-1b pelle-like protein kinase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X A7.3\|X 37.61 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008363.2	NP_032389.2	interleukin-1 receptor-associated kinase 1 isoform 4
NM_001177974.1	NP_001171445.1	interleukin-1 receptor-associated kinase 1 isoform 4
NM_001177976.1	NP_001171447.1	interleukin-1 receptor-associated kinase 1 isoform 2
NM_001177973.1	NP_001171444.1	interleukin-1 receptor-associated kinase 1 isoform 1
NM_001177975.1	NP_001171446.1	interleukin-1 receptor-associated kinase 1 isoform 3

Pathways from BioSystems

Homologies

Arabidopsis thaliana (thale cress)	AT4G32710	NP_567903.3
Homo sapiens (human)	IRAK1	NP_001560.2
Canis lupus familiaris (dog)	IRAK1	XP_549367.2
Rattus norvegicus (Norway rat)	Irak1	NP_001121027.1
Xenopus tropicalis (tropical clawed frog)	irak1	NP_001006713.1
Danio rerio (zebrafish)	irak1	XP_005166760.1
Bos taurus (cattle)	IRAK1	NP_001035645.1
Mus musculus (house mouse)	Irak1	NP_001171446.1
Pan troglodytes (chimpanzee)	IRAK1	XP_521332.3

Gene Ontology
Bibliography

Related articles in PubMed

Nod1-mediated lipolysis promotes diacylglycerol accumulation and successive inflammation via PKCδ-IRAK axis in adipocytes.
Sharma A, Maurya CK, Arha D, Rai AK, Singh S, Varshney S, Schertzer JD, Tamrakar AK
Biochimica et biophysica acta. Molecular basis of disease1865(1)136-146(2019 01)

Down-regulation of IRAK1 attenuates podocyte apoptosis in diabetic nephropathy through PI3K/Akt signaling pathway.
Zhang Y, Chen X, Yuan L, Zhang Y, Wu J, Guo N, Chen X, Liu J
Biochemical and biophysical research communications506(3)529-535(2018 11)

Globular Adiponectin Exerts a Pro-Inflammatory Effect via IκB/NF-κB Pathway Activation and Anti-Inflammatory Effect by IRAK-1 Downregulation.
Lee KH, Jeong J, Woo J, Lee CH, Yoo CG
Molecules and cells41(8)762-770(2018 Aug)

Endotoxin Tolerant Dendritic Cells Suppress Inflammatory Responses in Splenocytes via Interleukin-1 Receptor Associated Kinase (IRAK)-M and Programmed Death-Ligand 1 (PDL-1).
Zhou Y, Xia Q, Wang X, Fu S
Medical science monitor : international medical journal of experimental and clinical research244798-4806(2018 Jul)

Anti-inflammatory effects of a novel compound, MPQP, through the inhibition of IRAK1 signaling pathways in LPS-stimulated RAW 264.7 macrophages.
Kim BR, Cho YC, Cho S
BMB reports51(6)308-313(2018 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Irak1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Irak1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu18682	NM_001177974.1 Latest version!	Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu18682	NM_008363.2 Latest version!	Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu19389	NM_001177976.1 Latest version!	Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu19477	NM_001177975.1 Latest version!	Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu19584	NM_001177973.1 Latest version!	Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Irak1 ( NM_008363.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032389.2 Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu18682
Clone ID Related Accession (Same CDS sequence)	NM_008363.2 , NM_001177974.1
Accession Version	NM_008363.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2133bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Mus musculus(house mouse)
Product	interleukin-1 receptor-associated kinase 1 isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL672002.14 and AF103876.1. On Nov 8, 2006 this sequence version replaced NM_008363.1. Transcript Variant: This variant (4) has multiple differences in the coding region but maintains the reading frame compared to variant 1. The resulting protein (isoform 4) is shorter but has the same N- and C-termini compared to isoform 1. Variants 4 and 5 encode the same protein (isoform 4). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY184362.1, U56773.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGGGG GGCCGGGCCC CGGGGAGCCT GTGGTTCCAG GCGCCCAGCA CTTCTTGTAC 
GAGGTGCCAC CCTGGGTTAT GTGCCGCTTC TACAAAGTGA TGGACGCCCT GGAGCCCGCC 
GACTGGTGCC AGTTCGCGGC CTTGATCGTG CGCGACCAGA CAGAGCTGCG GCTGTGCGAG 
CGCTCCGAGC AGCGCACAGC CAGTGTTCTG TGGCCCTGGA TCAACCGCAA CGCGCGCGTA 
GCTGACCTCG TTCACATCCT CACGCACCTG CAGCTGCTGC GTGCGAGGGA CATCATCACA 
GCCTGGCACC CTCCTGCCCC CGTTGTGCCC CCAAGCACCG CTGCCCCAAG GCCCAGCAGC 
ATCTCTGCAG GCTCTGAGGC CGGGGACTGG AGCCCCCGGA AATTGCAGTC CTCTGCCTCC 
ACCTTCCTCT CCCCAGCTTT TCCAGGCTCC CAGACCCATT CTGAGTCAGA GCTCCTCCAG 
GTTCCACTCC CTGTTTCCCT CGGGCCACCA CTACCATCTT CAGCCCCTTC CTCCACCAAG 
TCAAGCCCAG AGAGCCCAGT GTCTGGCCTC CAAAGAGCCC ATCCCTCCCC GTTTTGCTGG 
CCCTTCTGTG AGATTTCCCA AGGCACCTGC AACTTCTCTG AAGAACTCAG GATTGGAGAG 
GGTGGTTTTG GATGTGTGTA CCGAGCAGTC ATGAGAAATA CTACATATGC TGTGAAGAGA 
CTGAAGGAGG AAGCTGACCT AGAGTGGACT ATGGTGAAAC AGAGCTTCTT AACAGAGGTG 
GAACAGCTAT CAAGGTTTCG TCACCCAAAT ATCGTAGACT TTGCTGGCTA CTGTGCAGAG 
AGTGGCTTAT ACTGCCTTGT TTATGGCTTC TTGCCCAATG GCTCCTTGGA GGATCAGCTC 
CACCTTCAGA CCCAGGCCTG CTCCCCACTT TCCTGGCCTC AACGACTGGA CATTCTTCTG 
GGCACAGCCC GGGCTATTCA GTTTTTACAT CAGGATAGCC CCAGCCTTAT CCATGGAGAC 
ATCAAGAGTT CTAACGTGCT TCTGGATGAG AGACTGATGC CCAAGCTGGG AGACTTTGGC 
CTGGCTCGTT TCAGCCGCTT TGCGGGGGCC AAAGCAAGCC AGAGCAGTAC TGTGGCCCGG 
ACTTCCACAG TTCGAGGTAC CCTCGCCTAC TTGCCTGAGG AGTACATCAA GACAGGCCGA 
CTGGCTGTGG ACACCGATAC CTTCAGCTTT GGGGTGGTAA TACTGGAGAC CCTTGCTGGT 
CAGAGGGCTG TGAGGACACA AGGTGCAAAG ACCAAGTATT TGAAAGACCT GATTGAAGAT 
GAGGCTGAAG AGGCTGGAGT GACCCTGAAA AGCACCCAGC CTACTCTGTG GGTGGGTGTA 
GCCACGGATG CTTGGGCTGC TCCAATTGCT GCCCAGATCT ATAAGAAGCA CCTGGACTCC 
AGACCTGGGC CCTGCCCACC CCAGTTGGGC CTGGCCCTGG CTCAACTAGC TTGCTGCTGC 
ATGCACCGTC GGGCCAAGAA GAGGCCCCCC ATGACCCAGG TATACAAGAG ACTAGAAGGG 
CTTCAGGCAG GGCCTCCCTG GGAGCTAGAG GTTGCCGGCC ATGGCTCCCC TTCCCCACAG 
GAGAACTCCT ACATGTCTAC CACTGGCAGT GCCCAGAGTG GGGATGAACC ATGGCAGCCT 
CTAGTAGTGA CCACAAGAGC CCCAGCCCAG GCTGCCCAGC AACTCCAGAG AAGTCCCAAC 
CAGCCAGTGG AAAGTGATGA GAGTGTTCCC GGCCTCTCTG CTACCCTGCA TTCCTGGCAC 
TTGACTCCAG GTTCCCACCC AAGCCCAGCG TCCTTCAGAG AGGCTAGCTG TACCCAGGGA 
GGCACTACCA GAGAATCAAG TGTGAGGAGT AGCCCAGGCT TCCAGCCTAC AACCATGGAA 
GGCTCACCCA CGGGCAGCTC ATCCCTGCTG TCATCAGAAC CACCACAGAT CATCATCAAC 
CCAGCCCGAC AGAAGATGGT ACAAAAGCTG GCTCTTTATG AAGAAGGGGT CTTGGATAGC 
CTGCAACTGC TGTCATCAGG CTTTTTCCCA GGCTTGGATT TAGAACCTGA AAAGAGCCAG 
GGACCTGAAG AAAGTGATGA ATTCCAGAGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032389.2
CDS	177..2309
Translation	MAGGPGPGEPVVPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSEQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPAPVVPPSTAAPRPSSISAGSEAGDWSPRKLQSSASTFLSPAFPGSQTHSESELLQVPLPVSLGPPLPSSAPSSTKSSPESPVSGLQRAHPSPFCWPFCEISQGTCNFSEELRIGEGGFGCVYRAVMRNTTYAVKRLKEEADLEWTMVKQSFLTEVEQLSRFRHPNIVDFAGYCAESGLYCLVYGFLPNGSLEDQLHLQTQACSPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDEAEEAGVTLKSTQPTLWVGVATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYKRLEGLQAGPPWELEVAGHGSPSPQENSYMSTTGSAQSGDEPWQPLVVTTRAPAQAAQQLQRSPNQPVESDESVPGLSATLHSWHLTPGSHPSPASFREASCTQGGTTRESSVRSSPGFQPTTMEGSPTGSSSLLSSEPPQIIINPARQKMVQKLALYEEGVLDSLQLLSSGFFPGLDLEPEKSQGPEESDEFQS

Target ORF information:

RefSeq Version	NM_008363.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008363.2

ORF Insert Sequence:

ATGGCCGGGG GGCCGGGCCC CGGGGAGCCT GTGGTTCCAG GCGCCCAGCA CTTCTTGTAC 
GAGGTGCCAC CCTGGGTTAT GTGCCGCTTC TACAAAGTGA TGGACGCCCT GGAGCCCGCC 
GACTGGTGCC AGTTCGCGGC CTTGATCGTG CGCGACCAGA CAGAGCTGCG GCTGTGCGAG 
CGCTCCGAGC AGCGCACAGC CAGTGTTCTG TGGCCCTGGA TCAACCGCAA CGCGCGCGTA 
GCTGACCTCG TTCACATCCT CACGCACCTG CAGCTGCTGC GTGCGAGGGA CATCATCACA 
GCCTGGCACC CTCCTGCCCC CGTTGTGCCC CCAAGCACCG CTGCCCCAAG GCCCAGCAGC 
ATCTCTGCAG GCTCTGAGGC CGGGGACTGG AGCCCCCGGA AATTGCAGTC CTCTGCCTCC 
ACCTTCCTCT CCCCAGCTTT TCCAGGCTCC CAGACCCATT CTGAGTCAGA GCTCCTCCAG 
GTTCCACTCC CTGTTTCCCT CGGGCCACCA CTACCATCTT CAGCCCCTTC CTCCACCAAG 
TCAAGCCCAG AGAGCCCAGT GTCTGGCCTC CAAAGAGCCC ATCCCTCCCC GTTTTGCTGG 
CCCTTCTGTG AGATTTCCCA AGGCACCTGC AACTTCTCTG AAGAACTCAG GATTGGAGAG 
GGTGGTTTTG GATGTGTGTA CCGAGCAGTC ATGAGAAATA CTACATATGC TGTGAAGAGA 
CTGAAGGAGG AAGCTGACCT AGAGTGGACT ATGGTGAAAC AGAGCTTCTT AACAGAGGTG 
GAACAGCTAT CAAGGTTTCG TCACCCAAAT ATCGTAGACT TTGCTGGCTA CTGTGCAGAG 
AGTGGCTTAT ACTGCCTTGT TTATGGCTTC TTGCCCAATG GCTCCTTGGA GGATCAGCTC 
CACCTTCAGA CCCAGGCCTG CTCCCCACTT TCCTGGCCTC AACGACTGGA CATTCTTCTG 
GGCACAGCCC GGGCTATTCA GTTTTTACAT CAGGATAGCC CCAGCCTTAT CCATGGAGAC 
ATCAAGAGTT CTAACGTGCT TCTGGATGAG AGACTGATGC CCAAGCTGGG AGACTTTGGC 
CTGGCTCGTT TCAGCCGCTT TGCGGGGGCC AAAGCAAGCC AGAGCAGTAC TGTGGCCCGG 
ACTTCCACAG TTCGAGGTAC CCTCGCCTAC TTGCCTGAGG AGTACATCAA GACAGGCCGA 
CTGGCTGTGG ACACCGATAC CTTCAGCTTT GGGGTGGTAA TACTGGAGAC CCTTGCTGGT 
CAGAGGGCTG TGAGGACACA AGGTGCAAAG ACCAAGTATT TGAAAGACCT GATTGAAGAT 
GAGGCTGAAG AGGCTGGAGT GACCCTGAAA AGCACCCAGC CTACTCTGTG GGTGGGTGTA 
GCCACGGATG CTTGGGCTGC TCCAATTGCT GCCCAGATCT ATAAGAAGCA CCTGGACTCC 
AGACCTGGGC CCTGCCCACC CCAGTTGGGC CTGGCCCTGG CTCAACTAGC TTGCTGCTGC 
ATGCACCGTC GGGCCAAGAA GAGGCCCCCC ATGACCCAGG TATACAAGAG ACTAGAAGGG 
CTTCAGGCAG GGCCTCCCTG GGAGCTAGAG GTTGCCGGCC ATGGCTCCCC TTCCCCACAG 
GAGAACTCCT ACATGTCTAC CACTGGCAGT GCCCAGAGTG GGGATGAACC ATGGCAGCCT 
CTAGTAGTGA CCACAAGAGC CCCAGCCCAG GCTGCCCAGC AACTCCAGAG AAGTCCCAAC 
CAGCCAGTGG AAAGTGATGA GAGTGTTCCC GGCCTCTCTG CTACCCTGCA TTCCTGGCAC 
TTGACTCCAG GTTCCCACCC AAGCCCAGCG TCCTTCAGAG AGGCTAGCTG TACCCAGGGA 
GGCACTACCA GAGAATCAAG TGTGAGGAGT AGCCCAGGCT TCCAGCCTAC AACCATGGAA 
GGCTCACCCA CGGGCAGCTC ATCCCTGCTG TCATCAGAAC CACCACAGAT CATCATCAAC 
CCAGCCCGAC AGAAGATGGT ACAAAAGCTG GCTCTTTATG AAGAAGGGGT CTTGGATAGC 
CTGCAACTGC TGTCATCAGG CTTTTTCCCA GGCTTGGATT TAGAACCTGA AAAGAGCCAG 
GGACCTGAAG AAAGTGATGA ATTCCAGAGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irak1 ( NM_001177974.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001171445.1 Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu18682
Clone ID Related Accession (Same CDS sequence)	NM_008363.2 , NM_001177974.1
Accession Version	NM_001177974.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2133bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Mus musculus(house mouse)
Product	interleukin-1 receptor-associated kinase 1 isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL672002.14, U56773.2 and BP760087.1. Transcript Variant: This variant (5) has multiple differences in the coding region but maintains the reading frame compared to variant 1. The resulting protein (isoform 4) is shorter but has the same N- and C-termini compared to isoform 1. Variants 4 and 5 encode the same protein (isoform 4). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY184363.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGGGG GGCCGGGCCC CGGGGAGCCT GTGGTTCCAG GCGCCCAGCA CTTCTTGTAC 
GAGGTGCCAC CCTGGGTTAT GTGCCGCTTC TACAAAGTGA TGGACGCCCT GGAGCCCGCC 
GACTGGTGCC AGTTCGCGGC CTTGATCGTG CGCGACCAGA CAGAGCTGCG GCTGTGCGAG 
CGCTCCGAGC AGCGCACAGC CAGTGTTCTG TGGCCCTGGA TCAACCGCAA CGCGCGCGTA 
GCTGACCTCG TTCACATCCT CACGCACCTG CAGCTGCTGC GTGCGAGGGA CATCATCACA 
GCCTGGCACC CTCCTGCCCC CGTTGTGCCC CCAAGCACCG CTGCCCCAAG GCCCAGCAGC 
ATCTCTGCAG GCTCTGAGGC CGGGGACTGG AGCCCCCGGA AATTGCAGTC CTCTGCCTCC 
ACCTTCCTCT CCCCAGCTTT TCCAGGCTCC CAGACCCATT CTGAGTCAGA GCTCCTCCAG 
GTTCCACTCC CTGTTTCCCT CGGGCCACCA CTACCATCTT CAGCCCCTTC CTCCACCAAG 
TCAAGCCCAG AGAGCCCAGT GTCTGGCCTC CAAAGAGCCC ATCCCTCCCC GTTTTGCTGG 
CCCTTCTGTG AGATTTCCCA AGGCACCTGC AACTTCTCTG AAGAACTCAG GATTGGAGAG 
GGTGGTTTTG GATGTGTGTA CCGAGCAGTC ATGAGAAATA CTACATATGC TGTGAAGAGA 
CTGAAGGAGG AAGCTGACCT AGAGTGGACT ATGGTGAAAC AGAGCTTCTT AACAGAGGTG 
GAACAGCTAT CAAGGTTTCG TCACCCAAAT ATCGTAGACT TTGCTGGCTA CTGTGCAGAG 
AGTGGCTTAT ACTGCCTTGT TTATGGCTTC TTGCCCAATG GCTCCTTGGA GGATCAGCTC 
CACCTTCAGA CCCAGGCCTG CTCCCCACTT TCCTGGCCTC AACGACTGGA CATTCTTCTG 
GGCACAGCCC GGGCTATTCA GTTTTTACAT CAGGATAGCC CCAGCCTTAT CCATGGAGAC 
ATCAAGAGTT CTAACGTGCT TCTGGATGAG AGACTGATGC CCAAGCTGGG AGACTTTGGC 
CTGGCTCGTT TCAGCCGCTT TGCGGGGGCC AAAGCAAGCC AGAGCAGTAC TGTGGCCCGG 
ACTTCCACAG TTCGAGGTAC CCTCGCCTAC TTGCCTGAGG AGTACATCAA GACAGGCCGA 
CTGGCTGTGG ACACCGATAC CTTCAGCTTT GGGGTGGTAA TACTGGAGAC CCTTGCTGGT 
CAGAGGGCTG TGAGGACACA AGGTGCAAAG ACCAAGTATT TGAAAGACCT GATTGAAGAT 
GAGGCTGAAG AGGCTGGAGT GACCCTGAAA AGCACCCAGC CTACTCTGTG GGTGGGTGTA 
GCCACGGATG CTTGGGCTGC TCCAATTGCT GCCCAGATCT ATAAGAAGCA CCTGGACTCC 
AGACCTGGGC CCTGCCCACC CCAGTTGGGC CTGGCCCTGG CTCAACTAGC TTGCTGCTGC 
ATGCACCGTC GGGCCAAGAA GAGGCCCCCC ATGACCCAGG TATACAAGAG ACTAGAAGGG 
CTTCAGGCAG GGCCTCCCTG GGAGCTAGAG GTTGCCGGCC ATGGCTCCCC TTCCCCACAG 
GAGAACTCCT ACATGTCTAC CACTGGCAGT GCCCAGAGTG GGGATGAACC ATGGCAGCCT 
CTAGTAGTGA CCACAAGAGC CCCAGCCCAG GCTGCCCAGC AACTCCAGAG AAGTCCCAAC 
CAGCCAGTGG AAAGTGATGA GAGTGTTCCC GGCCTCTCTG CTACCCTGCA TTCCTGGCAC 
TTGACTCCAG GTTCCCACCC AAGCCCAGCG TCCTTCAGAG AGGCTAGCTG TACCCAGGGA 
GGCACTACCA GAGAATCAAG TGTGAGGAGT AGCCCAGGCT TCCAGCCTAC AACCATGGAA 
GGCTCACCCA CGGGCAGCTC ATCCCTGCTG TCATCAGAAC CACCACAGAT CATCATCAAC 
CCAGCCCGAC AGAAGATGGT ACAAAAGCTG GCTCTTTATG AAGAAGGGGT CTTGGATAGC 
CTGCAACTGC TGTCATCAGG CTTTTTCCCA GGCTTGGATT TAGAACCTGA AAAGAGCCAG 
GGACCTGAAG AAAGTGATGA ATTCCAGAGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171445.1
CDS	177..2309
Translation	MAGGPGPGEPVVPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSEQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPAPVVPPSTAAPRPSSISAGSEAGDWSPRKLQSSASTFLSPAFPGSQTHSESELLQVPLPVSLGPPLPSSAPSSTKSSPESPVSGLQRAHPSPFCWPFCEISQGTCNFSEELRIGEGGFGCVYRAVMRNTTYAVKRLKEEADLEWTMVKQSFLTEVEQLSRFRHPNIVDFAGYCAESGLYCLVYGFLPNGSLEDQLHLQTQACSPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDEAEEAGVTLKSTQPTLWVGVATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYKRLEGLQAGPPWELEVAGHGSPSPQENSYMSTTGSAQSGDEPWQPLVVTTRAPAQAAQQLQRSPNQPVESDESVPGLSATLHSWHLTPGSHPSPASFREASCTQGGTTRESSVRSSPGFQPTTMEGSPTGSSSLLSSEPPQIIINPARQKMVQKLALYEEGVLDSLQLLSSGFFPGLDLEPEKSQGPEESDEFQS

Target ORF information:

RefSeq Version	NM_001177974.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001177974.1

ORF Insert Sequence:

ATGGCCGGGG GGCCGGGCCC CGGGGAGCCT GTGGTTCCAG GCGCCCAGCA CTTCTTGTAC 
GAGGTGCCAC CCTGGGTTAT GTGCCGCTTC TACAAAGTGA TGGACGCCCT GGAGCCCGCC 
GACTGGTGCC AGTTCGCGGC CTTGATCGTG CGCGACCAGA CAGAGCTGCG GCTGTGCGAG 
CGCTCCGAGC AGCGCACAGC CAGTGTTCTG TGGCCCTGGA TCAACCGCAA CGCGCGCGTA 
GCTGACCTCG TTCACATCCT CACGCACCTG CAGCTGCTGC GTGCGAGGGA CATCATCACA 
GCCTGGCACC CTCCTGCCCC CGTTGTGCCC CCAAGCACCG CTGCCCCAAG GCCCAGCAGC 
ATCTCTGCAG GCTCTGAGGC CGGGGACTGG AGCCCCCGGA AATTGCAGTC CTCTGCCTCC 
ACCTTCCTCT CCCCAGCTTT TCCAGGCTCC CAGACCCATT CTGAGTCAGA GCTCCTCCAG 
GTTCCACTCC CTGTTTCCCT CGGGCCACCA CTACCATCTT CAGCCCCTTC CTCCACCAAG 
TCAAGCCCAG AGAGCCCAGT GTCTGGCCTC CAAAGAGCCC ATCCCTCCCC GTTTTGCTGG 
CCCTTCTGTG AGATTTCCCA AGGCACCTGC AACTTCTCTG AAGAACTCAG GATTGGAGAG 
GGTGGTTTTG GATGTGTGTA CCGAGCAGTC ATGAGAAATA CTACATATGC TGTGAAGAGA 
CTGAAGGAGG AAGCTGACCT AGAGTGGACT ATGGTGAAAC AGAGCTTCTT AACAGAGGTG 
GAACAGCTAT CAAGGTTTCG TCACCCAAAT ATCGTAGACT TTGCTGGCTA CTGTGCAGAG 
AGTGGCTTAT ACTGCCTTGT TTATGGCTTC TTGCCCAATG GCTCCTTGGA GGATCAGCTC 
CACCTTCAGA CCCAGGCCTG CTCCCCACTT TCCTGGCCTC AACGACTGGA CATTCTTCTG 
GGCACAGCCC GGGCTATTCA GTTTTTACAT CAGGATAGCC CCAGCCTTAT CCATGGAGAC 
ATCAAGAGTT CTAACGTGCT TCTGGATGAG AGACTGATGC CCAAGCTGGG AGACTTTGGC 
CTGGCTCGTT TCAGCCGCTT TGCGGGGGCC AAAGCAAGCC AGAGCAGTAC TGTGGCCCGG 
ACTTCCACAG TTCGAGGTAC CCTCGCCTAC TTGCCTGAGG AGTACATCAA GACAGGCCGA 
CTGGCTGTGG ACACCGATAC CTTCAGCTTT GGGGTGGTAA TACTGGAGAC CCTTGCTGGT 
CAGAGGGCTG TGAGGACACA AGGTGCAAAG ACCAAGTATT TGAAAGACCT GATTGAAGAT 
GAGGCTGAAG AGGCTGGAGT GACCCTGAAA AGCACCCAGC CTACTCTGTG GGTGGGTGTA 
GCCACGGATG CTTGGGCTGC TCCAATTGCT GCCCAGATCT ATAAGAAGCA CCTGGACTCC 
AGACCTGGGC CCTGCCCACC CCAGTTGGGC CTGGCCCTGG CTCAACTAGC TTGCTGCTGC 
ATGCACCGTC GGGCCAAGAA GAGGCCCCCC ATGACCCAGG TATACAAGAG ACTAGAAGGG 
CTTCAGGCAG GGCCTCCCTG GGAGCTAGAG GTTGCCGGCC ATGGCTCCCC TTCCCCACAG 
GAGAACTCCT ACATGTCTAC CACTGGCAGT GCCCAGAGTG GGGATGAACC ATGGCAGCCT 
CTAGTAGTGA CCACAAGAGC CCCAGCCCAG GCTGCCCAGC AACTCCAGAG AAGTCCCAAC 
CAGCCAGTGG AAAGTGATGA GAGTGTTCCC GGCCTCTCTG CTACCCTGCA TTCCTGGCAC 
TTGACTCCAG GTTCCCACCC AAGCCCAGCG TCCTTCAGAG AGGCTAGCTG TACCCAGGGA 
GGCACTACCA GAGAATCAAG TGTGAGGAGT AGCCCAGGCT TCCAGCCTAC AACCATGGAA 
GGCTCACCCA CGGGCAGCTC ATCCCTGCTG TCATCAGAAC CACCACAGAT CATCATCAAC 
CCAGCCCGAC AGAAGATGGT ACAAAAGCTG GCTCTTTATG AAGAAGGGGT CTTGGATAGC 
CTGCAACTGC TGTCATCAGG CTTTTTCCCA GGCTTGGATT TAGAACCTGA AAAGAGCCAG 
GGACCTGAAG AAAGTGATGA ATTCCAGAGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irak1 ( NM_001177976.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001171447.1 Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 2, mRNA.

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CloneID	OMu19389
Clone ID Related Accession (Same CDS sequence)	NM_001177976.1
Accession Version	NM_001177976.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2139bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	interleukin-1 receptor-associated kinase 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL672002.14, U56773.2 and BP760087.1. Transcript Variant: This variant (2) has multiple differences in the coding region compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY184364.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGGGG GGCCGGGCCC CGGGGAGCCT GTGGTTCCAG GCGCCCAGCA CTTCTTGTAC 
GAGGTGCCAC CCTGGGTTAT GTGCCGCTTC TACAAAGTGA TGGACGCCCT GGAGCCCGCC 
GACTGGTGCC AGTTCGCGGC CTTGATCGTG CGCGACCAGA CAGAGCTGCG GCTGTGCGAG 
CGCTCCGAGC AGCGCACAGC CAGTGTTCTG TGGCCCTGGA TCAACCGCAA CGCGCGCGTA 
GCTGACCTCG TTCACATCCT CACGCACCTG CAGCTGCTGC GTGCGAGGGA CATCATCACA 
GCCTGGCACC CTCCTGCCCC CGTTGTGCCC CCAAGCACCG CTGCCCCAAG GCCCAGCAGC 
ATCTCTGCAG GCTCTGAGGC CGGGGACTGG AGCCCCCGGA AATTGCAGTC CTCTGCCTCC 
ACCTTCCTCT CCCCAGCTTT TCCAGGCTCC CAGACCCATT CTGAGTCAGA GCTCCTCCAG 
GTTCCACTCC CTGTTTCCCT CGGGCCACCA CTACCATCTT CAGCCCCTTC CTCCACCAAG 
TCAAGCCCAG AGAGCCCAGT GTCTGGCCTC CAAAGAGCCC ATCCCTCCCC GTTTTGCTGG 
CCCTTCTGTG AGATTTCCCA AGGCACCTGC AACTTCTCTG AAGAACTCAG GATTGGAGAG 
GGTGGTTTTG GATGTGTGTA CCGAGCAGTC ATGAGAAATA CTACATATGC TGTGAAGAGA 
CTGAAGGAGG AAGCTGACCT AGAGTGGACT ATGGTGAAAC AGAGCTTCTT AACAGAGGTG 
GAACAGCTAT CAAGGTTTCG TCACCCAAAT ATCGTAGACT TTGCTGGCTA CTGTGCAGAG 
AGTGGCTTAT ACTGCCTTGT TTATGGCTTC TTGCCCAATG GCTCCTTGGA GGATCAGCTC 
CACCTTCAGA CCCAGGCCTG CTCCCCACTT TCCTGGCCTC AACGACTGGA CATTCTTCTG 
GGCACAGCCC GGGCTATTCA GTTTTTACAT CAGGATAGCC CCAGCCTTAT CCATGGAGAC 
ATCAAGAGTT CTAACGTGCT TCTGGATGAG AGACTGATGC CCAAGCTGGG AGACTTTGGC 
CTGGCTCGTT TCAGCCGCTT TGCGGGGGCC AAAGCAAGCC AGAGCAGTAC TGTGGCCCGG 
ACTTCCACAG TTCGAGGTAC CCTCGCCTAC TTGCCTGAGG AGTACATCAA GACAGGCCGA 
CTGGCTGTGG ACACCGATAC CTTCAGCTTT GGGGTGGTAA TACTGGAGAC CCTTGCTGGT 
CAGAGGGCTG TGAGGACACA AGGTGCAAAG ACCAAGTATT TGAAAGACCT GATTGAAGAT 
GAGGCTGAAG AGGCTGGAGT GACCCTGAAA AGCACCCAGC CTACTCTGTG GGTGGGTGTA 
GCCACGGATG CTTGGGCTGC TCCAATTGCT GCCCAGATCT ATAAGAAGCA CCTGGACTCC 
AGACCTGGGC CCTGCCCACC CCAGTTGGGC CTGGCCCTGG CTCAACTAGC TTGCTGCTGC 
ATGCACCGTC GGGCCAAGAA GAGGCCCCCC ATGACCCAGG TATACAAGAG ACTAGAAGGG 
CTTCAGGCAG GGCCTCCCTG GGAGCTAGAG GTTGCCGGCC ATGGCTCCCC TTCCCCACAG 
GAGAACTCCT ACATGTCTAC CACTGGCAGT GCCCAGAGTG GGGATGAACC ATGGCAGCCT 
CTAGTAGTGA CCACAAGAGC CCCAGCCCAG GCTGCCCAGC AACTCCAGAG AAGTCCCAAC 
CAGCCAGTGG AAAGTGATGA GAGTGTTCCC GGCCTCTCTG CTACCCTGCA TTCCTGGCAC 
TTGACTCCAG GTTCCCACCC AAGCCCAGCG TCCTTCAGAG AGGCTAGCTG TACCCAGGGA 
GGCACTACCA GAGAATCAAG TGTGAGGAGT AGCCCAGGCT TCCAGCCTAC AACCATGGAA 
GGCTCACCCA CGGGCAGCTC ATCCCTGCTG TCATCAGAAC CACCACAGAT CATCATCAAC 
CCAGCCCGAC AGAAGATGGT ACAAAAGCTG GCTCTTTATG AAGAAGGGGT CTTGGATAGC 
CTGCAACTGC TGTCATCAGG CTTTTTCCCA GATTTCGTGG ATATTGATGC TATTGGAATT 
GAAGCCTTCA TGTCTGAATT ATTCATCAAT CATATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171447.1
CDS	177..2315
Translation	MAGGPGPGEPVVPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSEQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPAPVVPPSTAAPRPSSISAGSEAGDWSPRKLQSSASTFLSPAFPGSQTHSESELLQVPLPVSLGPPLPSSAPSSTKSSPESPVSGLQRAHPSPFCWPFCEISQGTCNFSEELRIGEGGFGCVYRAVMRNTTYAVKRLKEEADLEWTMVKQSFLTEVEQLSRFRHPNIVDFAGYCAESGLYCLVYGFLPNGSLEDQLHLQTQACSPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDEAEEAGVTLKSTQPTLWVGVATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYKRLEGLQAGPPWELEVAGHGSPSPQENSYMSTTGSAQSGDEPWQPLVVTTRAPAQAAQQLQRSPNQPVESDESVPGLSATLHSWHLTPGSHPSPASFREASCTQGGTTRESSVRSSPGFQPTTMEGSPTGSSSLLSSEPPQIIINPARQKMVQKLALYEEGVLDSLQLLSSGFFPDFVDIDAIGIEAFMSELFINHI

Target ORF information:

RefSeq Version	NM_001177976.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001177976.1

ORF Insert Sequence:

ATGGCCGGGG GGCCGGGCCC CGGGGAGCCT GTGGTTCCAG GCGCCCAGCA CTTCTTGTAC 
GAGGTGCCAC CCTGGGTTAT GTGCCGCTTC TACAAAGTGA TGGACGCCCT GGAGCCCGCC 
GACTGGTGCC AGTTCGCGGC CTTGATCGTG CGCGACCAGA CAGAGCTGCG GCTGTGCGAG 
CGCTCCGAGC AGCGCACAGC CAGTGTTCTG TGGCCCTGGA TCAACCGCAA CGCGCGCGTA 
GCTGACCTCG TTCACATCCT CACGCACCTG CAGCTGCTGC GTGCGAGGGA CATCATCACA 
GCCTGGCACC CTCCTGCCCC CGTTGTGCCC CCAAGCACCG CTGCCCCAAG GCCCAGCAGC 
ATCTCTGCAG GCTCTGAGGC CGGGGACTGG AGCCCCCGGA AATTGCAGTC CTCTGCCTCC 
ACCTTCCTCT CCCCAGCTTT TCCAGGCTCC CAGACCCATT CTGAGTCAGA GCTCCTCCAG 
GTTCCACTCC CTGTTTCCCT CGGGCCACCA CTACCATCTT CAGCCCCTTC CTCCACCAAG 
TCAAGCCCAG AGAGCCCAGT GTCTGGCCTC CAAAGAGCCC ATCCCTCCCC GTTTTGCTGG 
CCCTTCTGTG AGATTTCCCA AGGCACCTGC AACTTCTCTG AAGAACTCAG GATTGGAGAG 
GGTGGTTTTG GATGTGTGTA CCGAGCAGTC ATGAGAAATA CTACATATGC TGTGAAGAGA 
CTGAAGGAGG AAGCTGACCT AGAGTGGACT ATGGTGAAAC AGAGCTTCTT AACAGAGGTG 
GAACAGCTAT CAAGGTTTCG TCACCCAAAT ATCGTAGACT TTGCTGGCTA CTGTGCAGAG 
AGTGGCTTAT ACTGCCTTGT TTATGGCTTC TTGCCCAATG GCTCCTTGGA GGATCAGCTC 
CACCTTCAGA CCCAGGCCTG CTCCCCACTT TCCTGGCCTC AACGACTGGA CATTCTTCTG 
GGCACAGCCC GGGCTATTCA GTTTTTACAT CAGGATAGCC CCAGCCTTAT CCATGGAGAC 
ATCAAGAGTT CTAACGTGCT TCTGGATGAG AGACTGATGC CCAAGCTGGG AGACTTTGGC 
CTGGCTCGTT TCAGCCGCTT TGCGGGGGCC AAAGCAAGCC AGAGCAGTAC TGTGGCCCGG 
ACTTCCACAG TTCGAGGTAC CCTCGCCTAC TTGCCTGAGG AGTACATCAA GACAGGCCGA 
CTGGCTGTGG ACACCGATAC CTTCAGCTTT GGGGTGGTAA TACTGGAGAC CCTTGCTGGT 
CAGAGGGCTG TGAGGACACA AGGTGCAAAG ACCAAGTATT TGAAAGACCT GATTGAAGAT 
GAGGCTGAAG AGGCTGGAGT GACCCTGAAA AGCACCCAGC CTACTCTGTG GGTGGGTGTA 
GCCACGGATG CTTGGGCTGC TCCAATTGCT GCCCAGATCT ATAAGAAGCA CCTGGACTCC 
AGACCTGGGC CCTGCCCACC CCAGTTGGGC CTGGCCCTGG CTCAACTAGC TTGCTGCTGC 
ATGCACCGTC GGGCCAAGAA GAGGCCCCCC ATGACCCAGG TATACAAGAG ACTAGAAGGG 
CTTCAGGCAG GGCCTCCCTG GGAGCTAGAG GTTGCCGGCC ATGGCTCCCC TTCCCCACAG 
GAGAACTCCT ACATGTCTAC CACTGGCAGT GCCCAGAGTG GGGATGAACC ATGGCAGCCT 
CTAGTAGTGA CCACAAGAGC CCCAGCCCAG GCTGCCCAGC AACTCCAGAG AAGTCCCAAC 
CAGCCAGTGG AAAGTGATGA GAGTGTTCCC GGCCTCTCTG CTACCCTGCA TTCCTGGCAC 
TTGACTCCAG GTTCCCACCC AAGCCCAGCG TCCTTCAGAG AGGCTAGCTG TACCCAGGGA 
GGCACTACCA GAGAATCAAG TGTGAGGAGT AGCCCAGGCT TCCAGCCTAC AACCATGGAA 
GGCTCACCCA CGGGCAGCTC ATCCCTGCTG TCATCAGAAC CACCACAGAT CATCATCAAC 
CCAGCCCGAC AGAAGATGGT ACAAAAGCTG GCTCTTTATG AAGAAGGGGT CTTGGATAGC 
CTGCAACTGC TGTCATCAGG CTTTTTCCCA GATTTCGTGG ATATTGATGC TATTGGAATT 
GAAGCCTTCA TGTCTGAATT ATTCATCAAT CATATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irak1 ( NM_001177975.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001171446.1 Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu19477
Clone ID Related Accession (Same CDS sequence)	NM_001177975.1
Accession Version	NM_001177975.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	interleukin-1 receptor-associated kinase 1 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY729815.1, AK143694.1 and AL672002.14. Transcript Variant: This variant (3) lacks an alternate exon in the coding region compared to variant 1. The resulting protein (isoform 3) is shorter but has the same N- and C-termini compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK143694.1, AK045958.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGGGG GGCCGGGCCC CGGGGAGCCT GTGGTTCCAG GCGCCCAGCA CTTCTTGTAC 
GAGGTGCCAC CCTGGGTTAT GTGCCGCTTC TACAAAGTGA TGGACGCCCT GGAGCCCGCC 
GACTGGTGCC AGTTCGCGGC CTTGATCGTG CGCGACCAGA CAGAGCTGCG GCTGTGCGAG 
CGCTCCGAGC AGCGCACAGC CAGTGTTCTG TGGCCCTGGA TCAACCGCAA CGCGCGCGTA 
GCTGACCTCG TTCACATCCT CACGCACCTG CAGCTGCTGC GTGCGAGGGA CATCATCACA 
GCCTGGCACC CTCCTGCCCC CGTTGTGCCC CCAAGCACCG CTGCCCCAAG GCCCAGCAGC 
ATCTCTGCAG GCTCTGAGGC CGGGGACTGG AGCCCCCGGA AATTGCAGTC CTCTGCCTCC 
ACCTTCCTCT CCCCAGCTTT TCCAGGCTCC CAGACCCATT CTGAGTCAGA GCTCCTCCAG 
GTTCCACTCC CTGTTTCCCT CGGGCCACCA CTACCATCTT CAGCCCCTTC CTCCACCAAG 
CAGTCAAGCC CAGAGAGCCC AGTGTCTGGC CTCCAAAGAG CCCATCCCTC CCCGTTTTGC 
TGGCCCTTCT GTGAGATTTC CCAAGGCACC TGCAACTTCT CTGAAGAACT CAGGATTGGA 
GAGGGTGGTT TTGGATGTGT GTACCGAGCA GTCATGAGAA ATACTACATA TGCTGTGAAG 
AGACTGAAGG AGGAAGCTGA CCTAGAGTGG ACTATGGTGA AACAGAGCTT CTTAACAGAG 
GTGGAACAGC TATCAAGGTT TCGTCACCCA AATATCGTAG ACTTTGCTGG CTACTGTGCA 
GAGAGTGGCT TATACTGCCT TGTTTATGGC TTCTTGCCCA ATGGCTCCTT GGAGGATCAG 
CTCCACCTTC AGACCCAGGC CTGCTCCCCA CTTTCCTGGC CTCAACGACT GGACATTCTT 
CTGGGCACAG CCCGGGCTAT TCAGTTTTTA CATCAGGATA GCCCCAGCCT TATCCATGGA 
GACATCAAGA GTTCTAACGT GCTTCTGGAT GAGAGACTGA TGCCCAAGCT GGGAGACTTT 
GGCCTGGCTC GTTTCAGCCG CTTTGCGGGG GCCAAAGCAA GCCAGAGCAG TACTGTGGCC 
CGGACTTCCA CAGTTCGAGG TACCCTCGCC TACTTGCCTG AGGAGTACAT CAAGACAGGC 
CGACTGGCTG TGGACACCGA TACCTTCAGC TTTGGGGTGG TAATACTGGA GACCCTTGCT 
GGTCAGAGGG CTGTGAGGAC ACAAGGTGCA AAGACCAAGT ATTTGAAAGA CCTGATTGAA 
GATGAGGCTG AAGAGGCTGG AGTGACCCTG AAAAGCACCC AGCCTACTCT GTGGGTGGGT 
GTAGCCACGG ATGCTTGGGC TGCTCCAATT GCTGCCCAGA TCTATAAGAA GCACCTGGAC 
TCCAGACCTG GGCCCTGCCC ACCCCAGTTG GGCCTGGCCC TGGCTCAACT AGCTTGCTGC 
TGCATGCACC GTCGGGCCAA GAAGAGGCCC CCCATGACCC AGGTATACAA GAGACTAGAA 
GGGCTTCAGG CAGGGCCTCC CTGGGAGCTA GAGGTTGCCG GCCATGGCTC CCCTTCCCCA 
CAGGAGAACT CCTACATGTC TACCACTGGC AGTGCCCAGA GTGGGGATGA ACCATGGCAG 
CCTCTAGTAG TGACCACAAG AGCCCCAGCC CAGGCTGCCC AGCAACTCCA GAGAAGTCCC 
AACCAGCCAG TGGAAAGTGA TGAGAGTGTT CCCGGCCTCT CTGCTACCCT GCATTCCTGG 
CACTTGACTC CAGGTTCCCA CCCAAGCCCA GCGTCCTTCA GAGAGGCTAG CTGTACCCAG 
GGAGGCACTA CCAGAGAATC AAGTGTGAGG AGTAGCCCAG GCTTCCAGCC TACAACCATG 
GAAGGCTCAC CCACGGGCAG CTCATCCCTG CTGTCATCAG AACCACCACA GATCATCATC 
AACCCAGCCC GACAGAAGAT GGTACAAAAG CTGGCTCTTT ATGAAGAAGG GGTCTTGGAT 
AGCCTGCAAC TGCTGTCATC AGGCTTTTTC CCAGGCTTGG ATTTAGAACC TGAAAAGAGC 
CAGGGACCTG AAGAAAGTGA TGAATTCCAG AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171446.1
CDS	174..2309
Translation	MAGGPGPGEPVVPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSEQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPAPVVPPSTAAPRPSSISAGSEAGDWSPRKLQSSASTFLSPAFPGSQTHSESELLQVPLPVSLGPPLPSSAPSSTKQSSPESPVSGLQRAHPSPFCWPFCEISQGTCNFSEELRIGEGGFGCVYRAVMRNTTYAVKRLKEEADLEWTMVKQSFLTEVEQLSRFRHPNIVDFAGYCAESGLYCLVYGFLPNGSLEDQLHLQTQACSPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDEAEEAGVTLKSTQPTLWVGVATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYKRLEGLQAGPPWELEVAGHGSPSPQENSYMSTTGSAQSGDEPWQPLVVTTRAPAQAAQQLQRSPNQPVESDESVPGLSATLHSWHLTPGSHPSPASFREASCTQGGTTRESSVRSSPGFQPTTMEGSPTGSSSLLSSEPPQIIINPARQKMVQKLALYEEGVLDSLQLLSSGFFPGLDLEPEKSQGPEESDEFQS

Target ORF information:

RefSeq Version	NM_001177975.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001177975.1

ORF Insert Sequence:

ATGGCCGGGG GGCCGGGCCC CGGGGAGCCT GTGGTTCCAG GCGCCCAGCA CTTCTTGTAC 
GAGGTGCCAC CCTGGGTTAT GTGCCGCTTC TACAAAGTGA TGGACGCCCT GGAGCCCGCC 
GACTGGTGCC AGTTCGCGGC CTTGATCGTG CGCGACCAGA CAGAGCTGCG GCTGTGCGAG 
CGCTCCGAGC AGCGCACAGC CAGTGTTCTG TGGCCCTGGA TCAACCGCAA CGCGCGCGTA 
GCTGACCTCG TTCACATCCT CACGCACCTG CAGCTGCTGC GTGCGAGGGA CATCATCACA 
GCCTGGCACC CTCCTGCCCC CGTTGTGCCC CCAAGCACCG CTGCCCCAAG GCCCAGCAGC 
ATCTCTGCAG GCTCTGAGGC CGGGGACTGG AGCCCCCGGA AATTGCAGTC CTCTGCCTCC 
ACCTTCCTCT CCCCAGCTTT TCCAGGCTCC CAGACCCATT CTGAGTCAGA GCTCCTCCAG 
GTTCCACTCC CTGTTTCCCT CGGGCCACCA CTACCATCTT CAGCCCCTTC CTCCACCAAG 
CAGTCAAGCC CAGAGAGCCC AGTGTCTGGC CTCCAAAGAG CCCATCCCTC CCCGTTTTGC 
TGGCCCTTCT GTGAGATTTC CCAAGGCACC TGCAACTTCT CTGAAGAACT CAGGATTGGA 
GAGGGTGGTT TTGGATGTGT GTACCGAGCA GTCATGAGAA ATACTACATA TGCTGTGAAG 
AGACTGAAGG AGGAAGCTGA CCTAGAGTGG ACTATGGTGA AACAGAGCTT CTTAACAGAG 
GTGGAACAGC TATCAAGGTT TCGTCACCCA AATATCGTAG ACTTTGCTGG CTACTGTGCA 
GAGAGTGGCT TATACTGCCT TGTTTATGGC TTCTTGCCCA ATGGCTCCTT GGAGGATCAG 
CTCCACCTTC AGACCCAGGC CTGCTCCCCA CTTTCCTGGC CTCAACGACT GGACATTCTT 
CTGGGCACAG CCCGGGCTAT TCAGTTTTTA CATCAGGATA GCCCCAGCCT TATCCATGGA 
GACATCAAGA GTTCTAACGT GCTTCTGGAT GAGAGACTGA TGCCCAAGCT GGGAGACTTT 
GGCCTGGCTC GTTTCAGCCG CTTTGCGGGG GCCAAAGCAA GCCAGAGCAG TACTGTGGCC 
CGGACTTCCA CAGTTCGAGG TACCCTCGCC TACTTGCCTG AGGAGTACAT CAAGACAGGC 
CGACTGGCTG TGGACACCGA TACCTTCAGC TTTGGGGTGG TAATACTGGA GACCCTTGCT 
GGTCAGAGGG CTGTGAGGAC ACAAGGTGCA AAGACCAAGT ATTTGAAAGA CCTGATTGAA 
GATGAGGCTG AAGAGGCTGG AGTGACCCTG AAAAGCACCC AGCCTACTCT GTGGGTGGGT 
GTAGCCACGG ATGCTTGGGC TGCTCCAATT GCTGCCCAGA TCTATAAGAA GCACCTGGAC 
TCCAGACCTG GGCCCTGCCC ACCCCAGTTG GGCCTGGCCC TGGCTCAACT AGCTTGCTGC 
TGCATGCACC GTCGGGCCAA GAAGAGGCCC CCCATGACCC AGGTATACAA GAGACTAGAA 
GGGCTTCAGG CAGGGCCTCC CTGGGAGCTA GAGGTTGCCG GCCATGGCTC CCCTTCCCCA 
CAGGAGAACT CCTACATGTC TACCACTGGC AGTGCCCAGA GTGGGGATGA ACCATGGCAG 
CCTCTAGTAG TGACCACAAG AGCCCCAGCC CAGGCTGCCC AGCAACTCCA GAGAAGTCCC 
AACCAGCCAG TGGAAAGTGA TGAGAGTGTT CCCGGCCTCT CTGCTACCCT GCATTCCTGG 
CACTTGACTC CAGGTTCCCA CCCAAGCCCA GCGTCCTTCA GAGAGGCTAG CTGTACCCAG 
GGAGGCACTA CCAGAGAATC AAGTGTGAGG AGTAGCCCAG GCTTCCAGCC TACAACCATG 
GAAGGCTCAC CCACGGGCAG CTCATCCCTG CTGTCATCAG AACCACCACA GATCATCATC 
AACCCAGCCC GACAGAAGAT GGTACAAAAG CTGGCTCTTT ATGAAGAAGG GGTCTTGGAT 
AGCCTGCAAC TGCTGTCATC AGGCTTTTTC CCAGGCTTGG ATTTAGAACC TGAAAAGAGC 
CAGGGACCTG AAGAAAGTGA TGAATTCCAG AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irak1 ( NM_001177973.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001171444.1 Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu19584
Clone ID Related Accession (Same CDS sequence)	NM_001177973.1
Accession Version	NM_001177973.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568908800000
Organism	Mus musculus(house mouse)
Product	interleukin-1 receptor-associated kinase 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL672002.14 and AK143694.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC004778.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGGGG GGCCGGGCCC CGGGGAGCCT GTGGTTCCAG GCGCCCAGCA CTTCTTGTAC 
GAGGTGCCAC CCTGGGTTAT GTGCCGCTTC TACAAAGTGA TGGACGCCCT GGAGCCCGCC 
GACTGGTGCC AGTTCGCGGC CTTGATCGTG CGCGACCAGA CAGAGCTGCG GCTGTGCGAG 
CGCTCCGAGC AGCGCACAGC CAGTGTTCTG TGGCCCTGGA TCAACCGCAA CGCGCGCGTA 
GCTGACCTCG TTCACATCCT CACGCACCTG CAGCTGCTGC GTGCGAGGGA CATCATCACA 
GCCTGGCACC CTCCTGCCCC CGTTGTGCCC CCAAGCACCG CTGCCCCAAG GCCCAGCAGC 
ATCTCTGCAG GCTCTGAGGC CGGGGACTGG AGCCCCCGGA AATTGCAGTC CTCTGCCTCC 
ACCTTCCTCT CCCCAGCTTT TCCAGGCTCC CAGACCCATT CTGAGTCAGA GCTCCTCCAG 
GTTCCACTCC CTGTTTCCCT CGGGCCACCA CTACCATCTT CAGCCCCTTC CTCCACCAAG 
CAGTCAAGCC CAGAGAGCCC AGTGTCTGGC CTCCAAAGAG CCCATCCCTC CCCGTTTTGC 
TGGCCCTTCT GTGAGATTTC CCAAGGCACC TGCAACTTCT CTGAAGAACT CAGGATTGGA 
GAGGGTGGTT TTGGATGTGT GTACCGAGCA GTCATGAGAA ATACTACATA TGCTGTGAAG 
AGACTGAAGG AGGAAGCTGA CCTAGAGTGG ACTATGGTGA AACAGAGCTT CTTAACAGAG 
GTGGAACAGC TATCAAGGTT TCGTCACCCA AATATCGTAG ACTTTGCTGG CTACTGTGCA 
GAGAGTGGCT TATACTGCCT TGTTTATGGC TTCTTGCCCA ATGGCTCCTT GGAGGATCAG 
CTCCACCTTC AGACCCAGGC CTGCTCCCCA CTTTCCTGGC CTCAACGACT GGACATTCTT 
CTGGGCACAG CCCGGGCTAT TCAGTTTTTA CATCAGGATA GCCCCAGCCT TATCCATGGA 
GACATCAAGA GTTCTAACGT GCTTCTGGAT GAGAGACTGA TGCCCAAGCT GGGAGACTTT 
GGCCTGGCTC GTTTCAGCCG CTTTGCGGGG GCCAAAGCAA GCCAGAGCAG TACTGTGGCC 
CGGACTTCCA CAGTTCGAGG TACCCTCGCC TACTTGCCTG AGGAGTACAT CAAGACAGGC 
CGACTGGCTG TGGACACCGA TACCTTCAGC TTTGGGGTGG TAATACTGGA GACCCTTGCT 
GGTCAGAGGG CTGTGAGGAC ACAAGGTGCA AAGACCAAGT ATTTGAAAGA CCTGATTGAA 
GATGAGGCTG AAGAGGCTGG AGTGACCCTG AAAAGCACCC AGCCTACTCT GTGGGTGGGT 
GTAGCCACGG ATGCTTGGGC TGCTCCAATT GCTGCCCAGA TCTATAAGAA GCACCTGGAC 
TCCAGACCTG GGCCCTGCCC ACCCCAGTTG GGCCTGGCCC TGGCTCAACT AGCTTGCTGC 
TGCATGCACC GTCGGGCCAA GAAGAGGCCC CCCATGACCC AGAGGCAAAA CTCCCAACAT 
TCCTTGCTTG CCCTTTGGCT CTATTTGGGG AGGTGCTCTG TGGAACTAAG TGGTAAAGGG 
CTGCTGCTTT GCTGGATGAG CCTCAGATCC CAGGAACAGG TATACAAGAG ACTAGAAGGG 
CTTCAGGCAG GGCCTCCCTG GGAGCTAGAG GTTGCCGGCC ATGGCTCCCC TTCCCCACAG 
GAGAACTCCT ACATGTCTAC CACTGGCAGT GCCCAGAGTG GGGATGAACC ATGGCAGCCT 
CTAGTAGTGA CCACAAGAGC CCCAGCCCAG GCTGCCCAGC AACTCCAGAG AAGTCCCAAC 
CAGCCAGTGG AAAGTGATGA GAGTGTTCCC GGCCTCTCTG CTACCCTGCA TTCCTGGCAC 
TTGACTCCAG GTTCCCACCC AAGCCCAGCG TCCTTCAGAG AGGCTAGCTG TACCCAGGGA 
GGCACTACCA GAGAATCAAG TGTGAGGAGT AGCCCAGGCT TCCAGCCTAC AACCATGGAA 
GGCTCACCCA CGGGCAGCTC ATCCCTGCTG TCATCAGAAC CACCACAGAT CATCATCAAC 
CCAGCCCGAC AGAAGATGGT ACAAAAGCTG GCTCTTTATG AAGAAGGGGT CTTGGATAGC 
CTGCAACTGC TGTCATCAGG CTTTTTCCCA GGCTTGGATT TAGAACCTGA AAAGAGCCAG 
GGACCTGAAG AAAGTGATGA ATTCCAGAGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171444.1
CDS	177..2429
Translation	MAGGPGPGEPVVPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSEQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPAPVVPPSTAAPRPSSISAGSEAGDWSPRKLQSSASTFLSPAFPGSQTHSESELLQVPLPVSLGPPLPSSAPSSTKQSSPESPVSGLQRAHPSPFCWPFCEISQGTCNFSEELRIGEGGFGCVYRAVMRNTTYAVKRLKEEADLEWTMVKQSFLTEVEQLSRFRHPNIVDFAGYCAESGLYCLVYGFLPNGSLEDQLHLQTQACSPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDEAEEAGVTLKSTQPTLWVGVATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQRQNSQHSLLALWLYLGRCSVELSGKGLLLCWMSLRSQEQVYKRLEGLQAGPPWELEVAGHGSPSPQENSYMSTTGSAQSGDEPWQPLVVTTRAPAQAAQQLQRSPNQPVESDESVPGLSATLHSWHLTPGSHPSPASFREASCTQGGTTRESSVRSSPGFQPTTMEGSPTGSSSLLSSEPPQIIINPARQKMVQKLALYEEGVLDSLQLLSSGFFPGLDLEPEKSQGPEESDEFQS

Target ORF information:

RefSeq Version	NM_001177973.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin-1 receptor-associated kinase 1 (Irak1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001177973.1

ORF Insert Sequence:

ATGGCCGGGG GGCCGGGCCC CGGGGAGCCT GTGGTTCCAG GCGCCCAGCA CTTCTTGTAC 
GAGGTGCCAC CCTGGGTTAT GTGCCGCTTC TACAAAGTGA TGGACGCCCT GGAGCCCGCC 
GACTGGTGCC AGTTCGCGGC CTTGATCGTG CGCGACCAGA CAGAGCTGCG GCTGTGCGAG 
CGCTCCGAGC AGCGCACAGC CAGTGTTCTG TGGCCCTGGA TCAACCGCAA CGCGCGCGTA 
GCTGACCTCG TTCACATCCT CACGCACCTG CAGCTGCTGC GTGCGAGGGA CATCATCACA 
GCCTGGCACC CTCCTGCCCC CGTTGTGCCC CCAAGCACCG CTGCCCCAAG GCCCAGCAGC 
ATCTCTGCAG GCTCTGAGGC CGGGGACTGG AGCCCCCGGA AATTGCAGTC CTCTGCCTCC 
ACCTTCCTCT CCCCAGCTTT TCCAGGCTCC CAGACCCATT CTGAGTCAGA GCTCCTCCAG 
GTTCCACTCC CTGTTTCCCT CGGGCCACCA CTACCATCTT CAGCCCCTTC CTCCACCAAG 
CAGTCAAGCC CAGAGAGCCC AGTGTCTGGC CTCCAAAGAG CCCATCCCTC CCCGTTTTGC 
TGGCCCTTCT GTGAGATTTC CCAAGGCACC TGCAACTTCT CTGAAGAACT CAGGATTGGA 
GAGGGTGGTT TTGGATGTGT GTACCGAGCA GTCATGAGAA ATACTACATA TGCTGTGAAG 
AGACTGAAGG AGGAAGCTGA CCTAGAGTGG ACTATGGTGA AACAGAGCTT CTTAACAGAG 
GTGGAACAGC TATCAAGGTT TCGTCACCCA AATATCGTAG ACTTTGCTGG CTACTGTGCA 
GAGAGTGGCT TATACTGCCT TGTTTATGGC TTCTTGCCCA ATGGCTCCTT GGAGGATCAG 
CTCCACCTTC AGACCCAGGC CTGCTCCCCA CTTTCCTGGC CTCAACGACT GGACATTCTT 
CTGGGCACAG CCCGGGCTAT TCAGTTTTTA CATCAGGATA GCCCCAGCCT TATCCATGGA 
GACATCAAGA GTTCTAACGT GCTTCTGGAT GAGAGACTGA TGCCCAAGCT GGGAGACTTT 
GGCCTGGCTC GTTTCAGCCG CTTTGCGGGG GCCAAAGCAA GCCAGAGCAG TACTGTGGCC 
CGGACTTCCA CAGTTCGAGG TACCCTCGCC TACTTGCCTG AGGAGTACAT CAAGACAGGC 
CGACTGGCTG TGGACACCGA TACCTTCAGC TTTGGGGTGG TAATACTGGA GACCCTTGCT 
GGTCAGAGGG CTGTGAGGAC ACAAGGTGCA AAGACCAAGT ATTTGAAAGA CCTGATTGAA 
GATGAGGCTG AAGAGGCTGG AGTGACCCTG AAAAGCACCC AGCCTACTCT GTGGGTGGGT 
GTAGCCACGG ATGCTTGGGC TGCTCCAATT GCTGCCCAGA TCTATAAGAA GCACCTGGAC 
TCCAGACCTG GGCCCTGCCC ACCCCAGTTG GGCCTGGCCC TGGCTCAACT AGCTTGCTGC 
TGCATGCACC GTCGGGCCAA GAAGAGGCCC CCCATGACCC AGAGGCAAAA CTCCCAACAT 
TCCTTGCTTG CCCTTTGGCT CTATTTGGGG AGGTGCTCTG TGGAACTAAG TGGTAAAGGG 
CTGCTGCTTT GCTGGATGAG CCTCAGATCC CAGGAACAGG TATACAAGAG ACTAGAAGGG 
CTTCAGGCAG GGCCTCCCTG GGAGCTAGAG GTTGCCGGCC ATGGCTCCCC TTCCCCACAG 
GAGAACTCCT ACATGTCTAC CACTGGCAGT GCCCAGAGTG GGGATGAACC ATGGCAGCCT 
CTAGTAGTGA CCACAAGAGC CCCAGCCCAG GCTGCCCAGC AACTCCAGAG AAGTCCCAAC 
CAGCCAGTGG AAAGTGATGA GAGTGTTCCC GGCCTCTCTG CTACCCTGCA TTCCTGGCAC 
TTGACTCCAG GTTCCCACCC AAGCCCAGCG TCCTTCAGAG AGGCTAGCTG TACCCAGGGA 
GGCACTACCA GAGAATCAAG TGTGAGGAGT AGCCCAGGCT TCCAGCCTAC AACCATGGAA 
GGCTCACCCA CGGGCAGCTC ATCCCTGCTG TCATCAGAAC CACCACAGAT CATCATCAAC 
CCAGCCCGAC AGAAGATGGT ACAAAAGCTG GCTCTTTATG AAGAAGGGGT CTTGGATAGC 
CTGCAACTGC TGTCATCAGG CTTTTTCCCA GGCTTGGATT TAGAACCTGA AAAGAGCCAG 
GGACCTGAAG AAAGTGATGA ATTCCAGAGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nod1-mediated lipolysis promotes diacylglycerol accumulation and successive inflammation via PKCδ-IRAK axis in adipocytes.
Biochimica et biophysica acta. Molecular basis of disease1865(1)136-146(2019 01)
Sharma A,Maurya CK,Arha D,Rai AK,Singh S,Varshney S,Schertzer JD,Tamrakar AK

Down-regulation of IRAK1 attenuates podocyte apoptosis in diabetic nephropathy through PI3K/Akt signaling pathway.
Biochemical and biophysical research communications506(3)529-535(2018 11)
Zhang Y,Chen X,Yuan L,Zhang Y,Wu J,Guo N,Chen X,Liu J

Globular Adiponectin Exerts a Pro-Inflammatory Effect via IκB/NF-κB Pathway Activation and Anti-Inflammatory Effect by IRAK-1 Downregulation.
Molecules and cells41(8)762-770(2018 Aug)
Lee KH,Jeong J,Woo J,Lee CH,Yoo CG

Endotoxin Tolerant Dendritic Cells Suppress Inflammatory Responses in Splenocytes via Interleukin-1 Receptor Associated Kinase (IRAK)-M and Programmed Death-Ligand 1 (PDL-1).
Medical science monitor : international medical journal of experimental and clinical research244798-4806(2018 Jul)
Zhou Y,Xia Q,Wang X,Fu S

Anti-inflammatory effects of a novel compound, MPQP, through the inhibition of IRAK1 signaling pathways in LPS-stimulated RAW 264.7 macrophages.
BMB reports51(6)308-313(2018 Jun)
Kim BR,Cho YC,Cho S

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Irak1 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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