Gucy2d cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gucy2d
Entrez Gene ID	14918
Full Name	guanylate cyclase 2d
General protein information	Preferred Names guanylate cyclase 2d Names olfactory guanylyl cyclase GC-D guanylyl cyclase 2d guanylyl cyclase D
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 E1\|7 53.86 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001130693.3	NP_001124165.1	olfactory guanylyl cyclase GC-D
XM_011241678.2	XP_011239980.2	olfactory guanylyl cyclase GC-D isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Gucy2d	NP_001124165.1
Canis lupus familiaris (dog)	LOC485179	XP_005633836.1
Danio rerio (zebrafish)	gucy2f	NP_571939.2
Xenopus tropicalis (tropical clawed frog)	LOC100489435	XP_004912270.1
Rattus norvegicus (Norway rat)	Gucy2d	NP_570093.1
Bos taurus (cattle)	GUCY2E	XP_003587048.2

Gene Ontology
Bibliography

Related articles in PubMed

The R838S Mutation in Retinal Guanylyl Cyclase 1 (RetGC1) Alters Calcium Sensitivity of cGMP Synthesis in the Retina and Causes Blindness in Transgenic Mice.
Dizhoor AM, Olshevskaya EV, Peshenko IV
The Journal of biological chemistry291(47)24504-24516(2016 Nov)

A Family of non-GPCR Chemosensors Defines an Alternative Logic for Mammalian Olfaction.
Greer PL, Bear DM, Lassance JM, Bloom ML, Tsukahara T, Pashkovski SL, Masuda FK, Nowlan AC, Kirchner R, Hoekstra HE, Datta SR
Cell165(7)1734-1748(2016 Jun)

Functional study of two biochemically unusual mutations in
Boye SL, Olshevskaya EV, Peshenko IV, McCullough KT, Boye SE, Dizhoor AM
Molecular vision221342-1351(2016)

Retinal guanylyl cyclase isozyme 1 is the preferential in vivo target for constitutively active GCAP1 mutants causing congenital degeneration of photoreceptors.
Olshevskaya EV, Peshenko IV, Savchenko AB, Dizhoor AM
The Journal of neuroscience : the official journal of the Society for Neuroscience32(21)7208-17(2012 May)

RD3, the protein associated with Leber congenital amaurosis type 12, is required for guanylate cyclase trafficking in photoreceptor cells.
Azadi S, Molday LL, Molday RS
Proceedings of the National Academy of Sciences of the United States of America107(49)21158-63(2010 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Gucy2d gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gucy2d cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06133	NM_001130693.3 Latest version!	Mus musculus guanylate cyclase 2d (Gucy2d), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OMu81921	XM_011241678.2 Latest version!	Mus musculus guanylate cyclase 2d (Gucy2d), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gucy2d ( NM_001130693.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001124165.1 Mus musculus guanylate cyclase 2d (Gucy2d), mRNA.

Price & Availability↑

CloneID	OMu06133
Clone ID Related Accession (Same CDS sequence)	NM_001130693.3
Accession Version	NM_001130693.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3354bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569772800000
Organism	Mus musculus(house mouse)
Product	olfactory guanylyl cyclase GC-D
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC111084.12 and AC115069.6. On Dec 17, 2013 this sequence version replaced NM_001130693.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN01164137 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END##

ATGGCAGGTC TGCAGCAGGG CTGTCACTTT GAAGGCCAGA ACTGGACAGC ACCACACTGG 
AAGACCTGCC TGCCCTGCCA GGGCCCGTGG AGACTCACTG TCAGTCATCT GAAGACTGTC 
TCTTCCATAT CAGTCCTCTC TGTGGTATTT TGGAGTGTCC TACTTTGGGC TGACTCCCTT 
TCCCTGTTAG CATGGGCAAG AGAGACCTTC ACCCTTGGGG TGCTGGGTCC CTGGGACTGT 
GACCCCATCT TTGCCCAGGC CCTCCCCAGC ATAGCTACCC AGCTGGCTGT AGATCAAGTT 
AATCAGGATG CCTCACTGCT GCCAGGCTCA CAGTTGGATT TCAAGGTCCT CCCCACAGGC 
TGTGACACTC CTCATGCCCT GGCCACATTC GTGGCCCACA AGAACATAGT GGCTGCTTTT 
GTAGGCCCTG TTAATCCTGG GTTCTGCTCA GCAGCAGCCC TGCTGGCCCA AGGCTGGGGC 
AAGTCCCTCT TCTCCTGGGC CTGTGAAGCT CCAGAGGGAG GAGGTGACTT AGTGCCCACT 
TTACCTTCTG CGGCCGATGT GCTACTGTCT GTCATGAGAC ACTTTGGCTG GGCTCGCTGG 
GCCATTGTGT CCTCTCACCA GGACATCTGG GTAACCACAG CCCAGCAGCT GGCCACTGCT 
TTCAGGACTC ATGGGCTGCC CATCGGACTG GTGACCTCTT TGGGACCTGG AGAGAAGGGG 
GCCACAGAGG TTTGCAAGCA GCTCCACAGT GTTCATGGTC TGAAAATTGT GGTTCTGTGC 
ATGCACTCGG CGCTGCTTGG AGGCCTGGAG CAGACCACCC TGCTGCACTG TGCCTGGGAG 
GAGGGCCTCA CAGACGGAAG GCTGGTCTTC CTGCCCTACG ACACGCTGCT CTTTGCCCTG 
CCCTATGGAA ACCGCTCCTA CCTGGTCCTG GATGACCATG GGCCCCTTCA GGAAGCCTAT 
GACGCAGTAC TCACTGTCAG TCTGGAGTCC AGTCCTGAGA GCCACGCCTT CACTGCTACC 
GAGATGAGTG GAGGGGCAAC TGCCAACTTG GAGCCAGAGC AGGTGTCCCC ACTCTTTGGA 
ACTATCTATG ATGCCGTCAT CCTGTTGGCC CATGCCCTGA ACCGATCTGA GACCCATGGA 
GCGGGGCTCT CAGGGGCTCA CTTAGGGGAC CACGTAAGAG CTCTTGATGT GGCTGGTTTT 
AGCCAGAGAA TCCGAACAGA TGGGAAAGGC AGAAGGCTAG CCCAATATGT CATCCTGGAC 
ACAGATGGTG AAGGAAGCCA GTTGGTTCCT ACCCACATTC TGGACACAAG CACATGGCAG 
GTGCAGCCTC TGGGAAAGCC TATACACTTT CCTGGGGGGA GCCCTCCAGC CCATGACGCC 
AGCTGCTGGT TCGACCCCAA CACACTATGC ATCAGAGGTG TGCAGCCCCT GGGCAGCCTC 
CTGACTCTGA CGATAGCCTG TGTCCTGGCA CTGGTTGGTG GATTCCTTGC TTACTTCATC 
AGGTTAGGCC TCCAGCAGCT GCGGCTGTTG CGGGGCCCCC ATCGGATCCT GCTGACATCT 
CAGGAGCTCA CCTTCCTCCA GCGGACCCCC AGCCGGAGGA GGCCACATGT GGACAGCGGC 
AGTGAGTCAA GAAGTGTGGT GGATGGTGGA AGTCCACGGT CGGTGACCCA GGGGTCAGCA 
AGGAGCCTAC CAGCCTTCCT GGAGCACACC AACGTGGCCC TGTACCAGGG AGAGTGGGTA 
TGGCTGAAGA AGTTTGAAGC AGGCGTGGCT CCTGATCTTC GGCCAAGTAG CCTTAGCTTC 
CTGAGAAAGT TGCGGGAGAT GCGGCATGAG AATGTTACTG CCTTCCTGGG CCTCTTTGTG 
GGCCCTGGGG TCAGTGCAAT GGTGCTGGAG CACTGTGCCC GTGGCAGCCT GGAGGACCTG 
CTGCAGAATG AGAACCTGAG GCTAGACTGG ACCTTCAAGG CCTCCTTACT GTTGGATCTG 
ATCCGAGGTT TGCGGTATCT GCACCATCGG CGCTTCCCCC ACGGGCGCCT CAAGTCCAGG 
AACTGTGTGG TGGACACTCG CTTTGTGCTC AAGATCACTG ATCATGGCTA TGCAGAGTTC 
CTGGAGTCTC ACTGTTCTTC CAGGCCCCAG CCAGCCCCAG AAGAGCTTCT GTGGACGGCT 
CCTGAGCTGC TGCGGGGGCC TGGGAAGGCC ACCTTCAAAG GTGATGTTTT CAGCTTGGCC 
ATCATCCTGC AGGAGGTACT GACCCGAGAC CCACCCTACT GCTCCTGGGG ACTCTCAGCA 
GAAGAGATCA TCCGGAAGGT GGCATCTCCC CCTCCTCTGT GCCGGCCACT GGTGTCCCCT 
GACCAGGGTC CCCTCGAGTG TATCCAGTTG ATGCAGCTAT GCTGGGAGGA AGCTCCAGAT 
GACAGGCCAA GCTTGGACCA GATCTACACA CAGTTCAAAA GCATCAACCA AGGCAAGAAG 
ACAAGTGTTG TAGACTCCAT GCTGCGGATG CTGGAGAAGT ATTCCGAAAG CCTGGAAGAT 
CTGGTCCAGG AGCGGACTGA GGAGCTGGAA CTGGAGAGGC GGAAGACAGA GAGGCTGCTC 
TCGCAGATGC TCCCTCCGTC TGTCGCCCAT GCTCTAAAGA TGGGGACAAC AGTGGAGCCC 
GAGTACTTCG ACCAGGTCAC CATCTATTTC AGTGACATCG TGGGCTTCAC CACCATCTCA 
GCCTTGAGTG AGCCCATTGA GGTGGTGGGC TTCCTCAATG ATCTCTACAC GCTGTTTGAT 
GCTGTTCTCG ACAGCCATGA TGTGTATAAG GTGGAGACCA TAGGGGATGC CTACATGGTG 
GCTTCTGGTC TCCCTCGGCG CAATGGAAAT CGGCACGCTG CTGAGATCGC CAACCTGGCC 
CTGGACATCC TTAGCTATGC AGGCAACTTT CGGATGAGGC ATGCACCCGA TGTACCCATC 
CGTGTCAGGG CAGGTCTGCA TTCAGGACCC TGTGTGGCAG GTGTTGTGGG TCTCACCATG 
CCTCGGTACT GCCTCTTTGG GGACACCGTC AACACTGCCT CTAGGATGGA GTCCACTGGG 
CTGCCTTACA GGATCCATGT CAGTCAAAGC ACTGTCCAGG CCCTGCTCAG CCTTGATGAA 
GGCTACAAAA TTGATGTCAG AGGTCAGACT GAACTGAAGG GGAAGGGCTT GGAGGAGACC 
TACTGGCTGA CAGGGAAGGT AGGATTCTGC AGACCCCTGC CTACACCTCT GTCTATCAAG 
CCTGGAGACC CATGGCAGGA CCGCATAAAC CAAGAAATCC GGACTGGCTT TGCCAAAGCA 
CGCCAGGGAC TGGCTGAGCC CAGAAAATCA GGGGAGGCTG GGCCAGGTCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124165.1
CDS	94..3447
Translation	MAGLQQGCHFEGQNWTAPHWKTCLPCQGPWRLTVSHLKTVSSISVLSVVFWSVLLWADSLSLLAWARETFTLGVLGPWDCDPIFAQALPSIATQLAVDQVNQDASLLPGSQLDFKVLPTGCDTPHALATFVAHKNIVAAFVGPVNPGFCSAAALLAQGWGKSLFSWACEAPEGGGDLVPTLPSAADVLLSVMRHFGWARWAIVSSHQDIWVTTAQQLATAFRTHGLPIGLVTSLGPGEKGATEVCKQLHSVHGLKIVVLCMHSALLGGLEQTTLLHCAWEEGLTDGRLVFLPYDTLLFALPYGNRSYLVLDDHGPLQEAYDAVLTVSLESSPESHAFTATEMSGGATANLEPEQVSPLFGTIYDAVILLAHALNRSETHGAGLSGAHLGDHVRALDVAGFSQRIRTDGKGRRLAQYVILDTDGEGSQLVPTHILDTSTWQVQPLGKPIHFPGGSPPAHDASCWFDPNTLCIRGVQPLGSLLTLTIACVLALVGGFLAYFIRLGLQQLRLLRGPHRILLTSQELTFLQRTPSRRRPHVDSGSESRSVVDGGSPRSVTQGSARSLPAFLEHTNVALYQGEWVWLKKFEAGVAPDLRPSSLSFLRKLREMRHENVTAFLGLFVGPGVSAMVLEHCARGSLEDLLQNENLRLDWTFKASLLLDLIRGLRYLHHRRFPHGRLKSRNCVVDTRFVLKITDHGYAEFLESHCSSRPQPAPEELLWTAPELLRGPGKATFKGDVFSLAIILQEVLTRDPPYCSWGLSAEEIIRKVASPPPLCRPLVSPDQGPLECIQLMQLCWEEAPDDRPSLDQIYTQFKSINQGKKTSVVDSMLRMLEKYSESLEDLVQERTEELELERRKTERLLSQMLPPSVAHALKMGTTVEPEYFDQVTIYFSDIVGFTTISALSEPIEVVGFLNDLYTLFDAVLDSHDVYKVETIGDAYMVASGLPRRNGNRHAAEIANLALDILSYAGNFRMRHAPDVPIRVRAGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSQSTVQALLSLDEGYKIDVRGQTELKGKGLEETYWLTGKVGFCRPLPTPLSIKPGDPWQDRINQEIRTGFAKARQGLAEPRKSGEAGPGP

Target ORF information:

RefSeq Version	NM_001130693.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanylate cyclase 2d (Gucy2d), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130693.3

ORF Insert Sequence:

ATGGCAGGTC TGCAGCAGGG CTGTCACTTT GAAGGCCAGA ACTGGACAGC ACCACACTGG 
AAGACCTGCC TGCCCTGCCA GGGCCCGTGG AGACTCACTG TCAGTCATCT GAAGACTGTC 
TCTTCCATAT CAGTCCTCTC TGTGGTATTT TGGAGTGTCC TACTTTGGGC TGACTCCCTT 
TCCCTGTTAG CATGGGCAAG AGAGACCTTC ACCCTTGGGG TGCTGGGTCC CTGGGACTGT 
GACCCCATCT TTGCCCAGGC CCTCCCCAGC ATAGCTACCC AGCTGGCTGT AGATCAAGTT 
AATCAGGATG CCTCACTGCT GCCAGGCTCA CAGTTGGATT TCAAGGTCCT CCCCACAGGC 
TGTGACACTC CTCATGCCCT GGCCACATTC GTGGCCCACA AGAACATAGT GGCTGCTTTT 
GTAGGCCCTG TTAATCCTGG GTTCTGCTCA GCAGCAGCCC TGCTGGCCCA AGGCTGGGGC 
AAGTCCCTCT TCTCCTGGGC CTGTGAAGCT CCAGAGGGAG GAGGTGACTT AGTGCCCACT 
TTACCTTCTG CGGCCGATGT GCTACTGTCT GTCATGAGAC ACTTTGGCTG GGCTCGCTGG 
GCCATTGTGT CCTCTCACCA GGACATCTGG GTAACCACAG CCCAGCAGCT GGCCACTGCT 
TTCAGGACTC ATGGGCTGCC CATCGGACTG GTGACCTCTT TGGGACCTGG AGAGAAGGGG 
GCCACAGAGG TTTGCAAGCA GCTCCACAGT GTTCATGGTC TGAAAATTGT GGTTCTGTGC 
ATGCACTCGG CGCTGCTTGG AGGCCTGGAG CAGACCACCC TGCTGCACTG TGCCTGGGAG 
GAGGGCCTCA CAGACGGAAG GCTGGTCTTC CTGCCCTACG ACACGCTGCT CTTTGCCCTG 
CCCTATGGAA ACCGCTCCTA CCTGGTCCTG GATGACCATG GGCCCCTTCA GGAAGCCTAT 
GACGCAGTAC TCACTGTCAG TCTGGAGTCC AGTCCTGAGA GCCACGCCTT CACTGCTACC 
GAGATGAGTG GAGGGGCAAC TGCCAACTTG GAGCCAGAGC AGGTGTCCCC ACTCTTTGGA 
ACTATCTATG ATGCCGTCAT CCTGTTGGCC CATGCCCTGA ACCGATCTGA GACCCATGGA 
GCGGGGCTCT CAGGGGCTCA CTTAGGGGAC CACGTAAGAG CTCTTGATGT GGCTGGTTTT 
AGCCAGAGAA TCCGAACAGA TGGGAAAGGC AGAAGGCTAG CCCAATATGT CATCCTGGAC 
ACAGATGGTG AAGGAAGCCA GTTGGTTCCT ACCCACATTC TGGACACAAG CACATGGCAG 
GTGCAGCCTC TGGGAAAGCC TATACACTTT CCTGGGGGGA GCCCTCCAGC CCATGACGCC 
AGCTGCTGGT TCGACCCCAA CACACTATGC ATCAGAGGTG TGCAGCCCCT GGGCAGCCTC 
CTGACTCTGA CGATAGCCTG TGTCCTGGCA CTGGTTGGTG GATTCCTTGC TTACTTCATC 
AGGTTAGGCC TCCAGCAGCT GCGGCTGTTG CGGGGCCCCC ATCGGATCCT GCTGACATCT 
CAGGAGCTCA CCTTCCTCCA GCGGACCCCC AGCCGGAGGA GGCCACATGT GGACAGCGGC 
AGTGAGTCAA GAAGTGTGGT GGATGGTGGA AGTCCACGGT CGGTGACCCA GGGGTCAGCA 
AGGAGCCTAC CAGCCTTCCT GGAGCACACC AACGTGGCCC TGTACCAGGG AGAGTGGGTA 
TGGCTGAAGA AGTTTGAAGC AGGCGTGGCT CCTGATCTTC GGCCAAGTAG CCTTAGCTTC 
CTGAGAAAGT TGCGGGAGAT GCGGCATGAG AATGTTACTG CCTTCCTGGG CCTCTTTGTG 
GGCCCTGGGG TCAGTGCAAT GGTGCTGGAG CACTGTGCCC GTGGCAGCCT GGAGGACCTG 
CTGCAGAATG AGAACCTGAG GCTAGACTGG ACCTTCAAGG CCTCCTTACT GTTGGATCTG 
ATCCGAGGTT TGCGGTATCT GCACCATCGG CGCTTCCCCC ACGGGCGCCT CAAGTCCAGG 
AACTGTGTGG TGGACACTCG CTTTGTGCTC AAGATCACTG ATCATGGCTA TGCAGAGTTC 
CTGGAGTCTC ACTGTTCTTC CAGGCCCCAG CCAGCCCCAG AAGAGCTTCT GTGGACGGCT 
CCTGAGCTGC TGCGGGGGCC TGGGAAGGCC ACCTTCAAAG GTGATGTTTT CAGCTTGGCC 
ATCATCCTGC AGGAGGTACT GACCCGAGAC CCACCCTACT GCTCCTGGGG ACTCTCAGCA 
GAAGAGATCA TCCGGAAGGT GGCATCTCCC CCTCCTCTGT GCCGGCCACT GGTGTCCCCT 
GACCAGGGTC CCCTCGAGTG TATCCAGTTG ATGCAGCTAT GCTGGGAGGA AGCTCCAGAT 
GACAGGCCAA GCTTGGACCA GATCTACACA CAGTTCAAAA GCATCAACCA AGGCAAGAAG 
ACAAGTGTTG TAGACTCCAT GCTGCGGATG CTGGAGAAGT ATTCCGAAAG CCTGGAAGAT 
CTGGTCCAGG AGCGGACTGA GGAGCTGGAA CTGGAGAGGC GGAAGACAGA GAGGCTGCTC 
TCGCAGATGC TCCCTCCGTC TGTCGCCCAT GCTCTAAAGA TGGGGACAAC AGTGGAGCCC 
GAGTACTTCG ACCAGGTCAC CATCTATTTC AGTGACATCG TGGGCTTCAC CACCATCTCA 
GCCTTGAGTG AGCCCATTGA GGTGGTGGGC TTCCTCAATG ATCTCTACAC GCTGTTTGAT 
GCTGTTCTCG ACAGCCATGA TGTGTATAAG GTGGAGACCA TAGGGGATGC CTACATGGTG 
GCTTCTGGTC TCCCTCGGCG CAATGGAAAT CGGCACGCTG CTGAGATCGC CAACCTGGCC 
CTGGACATCC TTAGCTATGC AGGCAACTTT CGGATGAGGC ATGCACCCGA TGTACCCATC 
CGTGTCAGGG CAGGTCTGCA TTCAGGACCC TGTGTGGCAG GTGTTGTGGG TCTCACCATG 
CCTCGGTACT GCCTCTTTGG GGACACCGTC AACACTGCCT CTAGGATGGA GTCCACTGGG 
CTGCCTTACA GGATCCATGT CAGTCAAAGC ACTGTCCAGG CCCTGCTCAG CCTTGATGAA 
GGCTACAAAA TTGATGTCAG AGGTCAGACT GAACTGAAGG GGAAGGGCTT GGAGGAGACC 
TACTGGCTGA CAGGGAAGGT AGGATTCTGC AGACCCCTGC CTACACCTCT GTCTATCAAG 
CCTGGAGACC CATGGCAGGA CCGCATAAAC CAAGAAATCC GGACTGGCTT TGCCAAAGCA 
CGCCAGGGAC TGGCTGAGCC CAGAAAATCA GGGGAGGCTG GGCCAGGTCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gucy2d ( XM_011241678.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239980.2 Mus musculus guanylate cyclase 2d (Gucy2d), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu81921
Clone ID Related Accession (Same CDS sequence)	XM_011241678.2
Accession Version	XM_011241678.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3426bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	olfactory guanylyl cyclase GC-D isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011241678.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END##

ATGGCGAGGG ATGTGGACTC TGTGCCCACA TCAGACACAG CAGGAACAAC AAGGCTTATC 
CATACATACC CTTCCTCAGG TCTGCAGCAG GGCTGTCACT TTGAAGGCCA GAACTGGACA 
GCACCACACT GGAAGACCTG CCTGCCCTGC CAGGGCCCGT GGAGACTCAC TGTCAGTCAT 
CTGAAGACTG TCTCTTCCAT ATCAGTCCTC TCTGTGGTAT TTTGGAGTGT CCTACTTTGG 
GCTGACTCCC TTTCCCTGTT AGCATGGGCA AGAGAGACCT TCACCCTTGG GGTGCTGGGT 
CCCTGGGACT GTGACCCCAT CTTTGCCCAG GCCCTCCCCA GCATAGCTAC CCAGCTGGCT 
GTAGATCAAG TTAATCAGGA TGCCTCACTG CTGCCAGGCT CACAGTTGGA TTTCAAGGTC 
CTCCCCACAG GCTGTGACAC TCCTCATGCC CTGGCCACAT TCGTGGCCCA CAAGAACATA 
GTGGCTGCTT TTGTAGGCCC TGTTAATCCT GGGTTCTGCT CAGCAGCAGC CCTGCTGGCC 
CAAGGCTGGG GCAAGTCCCT CTTCTCCTGG GCCTGTGAAG CTCCAGAGGG AGGAGGTGAC 
TTAGTGCCCA CTTTACCTTC TGCGGCCGAT GTGCTACTGT CTGTCATGAG ACACTTTGGC 
TGGGCTCGCT GGGCCATTGT GTCCTCTCAC CAGGACATCT GGGTAACCAC AGCCCAGCAG 
CTGGCCACTG CTTTCAGGAC TCATGGGCTG CCCATCGGAC TGGTGACCTC TTTGGGACCT 
GGAGAGAAGG GGGCCACAGA GGTTTGCAAG CAGCTCCACA GTGTTCATGG TCTGAAAATT 
GTGGTTCTGT GCATGCACTC GGCGCTGCTT GGAGGCCTGG AGCAGACCAC CCTGCTGCAC 
TGTGCCTGGG AGGAGGGCCT CACAGACGGA AGGCTGGTCT TCCTGCCCTA CGACACGCTG 
CTCTTTGCCC TGCCCTATGG AAACCGCTCC TACCTGGTCC TGGATGACCA TGGGCCCCTT 
CAGGAAGCCT ATGACGCAGT ACTCACTGTC AGTCTGGAGT CCAGTCCTGA GAGCCACGCC 
TTCACTGCTA CCGAGATGAG TGGAGGGGCA ACTGCCAACT TGGAGCCAGA GCAGGTGTCC 
CCACTCTTTG GAACTATCTA TGATGCCGTC ATCCTGTTGG CCCATGCCCT GAACCGATCT 
GAGACCCATG GAGCGGGGCT CTCAGGGGCT CACTTAGGGG ACCACGTAAG AGCTCTTGAT 
GTGGCTGGTT TTAGCCAGAG AATCCGAACA GATGGGAAAG GCAGAAGGCT AGCCCAATAT 
GTCATCCTGG ACACAGATGG TGAAGGAAGC CAGTTGGTTC CTACCCACAT TCTGGACACA 
AGCACATGGC AGGTGCAGCC TCTGGGAAAG CCTATACACT TTCCTGGGGG GAGCCCTCCA 
GCCCATGACG CCAGCTGCTG GTTCGACCCC AACACACTAT GCATCAGAGG TGTGCAGCCC 
CTGGGCAGCC TCCTGACTCT GACGATAGCC TGTGTCCTGG CACTGGTTGG TGGATTCCTT 
GCTTACTTCA TCAGGTTAGG CCTCCAGCAG CTGCGGCTGT TGCGGGGCCC CCATCGGATC 
CTGCTGACAT CTCAGGAGCT CACCTTCCTC CAGCGGACCC CCAGCCGGAG GAGGCCACAT 
GTGGACAGCG GCAGTGAGTC AAGAAGTGTG GTGGATGGTG GAAGTCCACG GTCGGTGACC 
CAGGGGTCAG CAAGGAGCCT ACCAGCCTTC CTGGAGCACA CCAACGTGGC CCTGTACCAG 
GGAGAGTGGG TATGGCTGAA GAAGTTTGAA GCAGGCGTGG CTCCTGATCT TCGGCCAAGT 
AGCCTTAGCT TCCTGAGAAA GTTGCGGGAG ATGCGGCATG AGAATGTTAC TGCCTTCCTG 
GGCCTCTTTG TGGGCCCTGG GGTCAGTGCA ATGGTGCTGG AGCACTGTGC CCGTGGCAGC 
CTGGAGGACC TGCTGCAGAA TGAGAACCTG AGGCTAGACT GGACCTTCAA GGCCTCCTTA 
CTGTTGGATC TGATCCGAGG TTTGCGGTAT CTGCACCATC GGCGCTTCCC CCACGGGCGC 
CTCAAGTCCA GGAACTGTGT GGTGGACACT CGCTTTGTGC TCAAGATCAC TGATCATGGC 
TATGCAGAGT TCCTGGAGTC TCACTGTTCT TCCAGGCCCC AGCCAGCCCC AGAAGAGCTT 
CTGTGGACGG CTCCTGAGCT GCTGCGGGGG CCTGGGAAGG CCACCTTCAA AGGTGATGTT 
TTCAGCTTGG CCATCATCCT GCAGGAGGTA CTGACCCGAG ACCCACCCTA CTGCTCCTGG 
GGACTCTCAG CAGAAGAGAT CATCCGGAAG GTGGCATCTC CCCCTCCTCT GTGCCGGCCA 
CTGGTGTCCC CTGACCAGGG TCCCCTCGAG TGTATCCAGT TGATGCAGCT ATGCTGGGAG 
GAAGCTCCAG ATGACAGGCC AAGCTTGGAC CAGATCTACA CACAGTTCAA AAGCATCAAC 
CAAGGCAAGA AGACAAGTGT TGTAGACTCC ATGCTGCGGA TGCTGGAGAA GTATTCCGAA 
AGCCTGGAAG ATCTGGTCCA GGAGCGGACT GAGGAGCTGG AACTGGAGAG GCGGAAGACA 
GAGAGGCTGC TCTCGCAGAT GCTCCCTCCG TCTGTCGCCC ATGCTCTAAA GATGGGGACA 
ACAGTGGAGC CCGAGTACTT CGACCAGGTC ACCATCTATT TCAGTGACAT CGTGGGCTTC 
ACCACCATCT CAGCCTTGAG TGAGCCCATT GAGGTGGTGG GCTTCCTCAA TGATCTCTAC 
ACGCTGTTTG ATGCTGTTCT CGACAGCCAT GATGTGTATA AGGTGGAGAC CATAGGGGAT 
GCCTACATGG TGGCTTCTGG TCTCCCTCGG CGCAATGGAA ATCGGCACGC TGCTGAGATC 
GCCAACCTGG CCCTGGACAT CCTTAGCTAT GCAGGCAACT TTCGGATGAG GCATGCACCC 
GATGTACCCA TCCGTGTCAG GGCAGGTCTG CATTCAGGAC CCTGTGTGGC AGGTGTTGTG 
GGTCTCACCA TGCCTCGGTA CTGCCTCTTT GGGGACACCG TCAACACTGC CTCTAGGATG 
GAGTCCACTG GGCTGCCTTA CAGGATCCAT GTCAGTCAAA GCACTGTCCA GGCCCTGCTC 
AGCCTTGATG AAGGCTACAA AATTGATGTC AGAGGTCAGA CTGAACTGAA GGGGAAGGGC 
TTGGAGGAGA CCTACTGGCT GACAGGGAAG GTAGGATTCT GCAGACCCCT GCCTACACCT 
CTGTCTATCA AGCCTGGAGA CCCATGGCAG GACCGCATAA ACCAAGAAAT CCGGACTGGC 
TTTGCCAAAG CACGCCAGGG ACTGGCTGAG CCCAGAAAAT CAGGGGAGGC TGGGCCAGGT 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239980.2
CDS	1..3426
Translation	MARDVDSVPTSDTAGTTRLIHTYPSSGLQQGCHFEGQNWTAPHWKTCLPCQGPWRLTVSHLKTVSSISVLSVVFWSVLLWADSLSLLAWARETFTLGVLGPWDCDPIFAQALPSIATQLAVDQVNQDASLLPGSQLDFKVLPTGCDTPHALATFVAHKNIVAAFVGPVNPGFCSAAALLAQGWGKSLFSWACEAPEGGGDLVPTLPSAADVLLSVMRHFGWARWAIVSSHQDIWVTTAQQLATAFRTHGLPIGLVTSLGPGEKGATEVCKQLHSVHGLKIVVLCMHSALLGGLEQTTLLHCAWEEGLTDGRLVFLPYDTLLFALPYGNRSYLVLDDHGPLQEAYDAVLTVSLESSPESHAFTATEMSGGATANLEPEQVSPLFGTIYDAVILLAHALNRSETHGAGLSGAHLGDHVRALDVAGFSQRIRTDGKGRRLAQYVILDTDGEGSQLVPTHILDTSTWQVQPLGKPIHFPGGSPPAHDASCWFDPNTLCIRGVQPLGSLLTLTIACVLALVGGFLAYFIRLGLQQLRLLRGPHRILLTSQELTFLQRTPSRRRPHVDSGSESRSVVDGGSPRSVTQGSARSLPAFLEHTNVALYQGEWVWLKKFEAGVAPDLRPSSLSFLRKLREMRHENVTAFLGLFVGPGVSAMVLEHCARGSLEDLLQNENLRLDWTFKASLLLDLIRGLRYLHHRRFPHGRLKSRNCVVDTRFVLKITDHGYAEFLESHCSSRPQPAPEELLWTAPELLRGPGKATFKGDVFSLAIILQEVLTRDPPYCSWGLSAEEIIRKVASPPPLCRPLVSPDQGPLECIQLMQLCWEEAPDDRPSLDQIYTQFKSINQGKKTSVVDSMLRMLEKYSESLEDLVQERTEELELERRKTERLLSQMLPPSVAHALKMGTTVEPEYFDQVTIYFSDIVGFTTISALSEPIEVVGFLNDLYTLFDAVLDSHDVYKVETIGDAYMVASGLPRRNGNRHAAEIANLALDILSYAGNFRMRHAPDVPIRVRAGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSQSTVQALLSLDEGYKIDVRGQTELKGKGLEETYWLTGKVGFCRPLPTPLSIKPGDPWQDRINQEIRTGFAKARQGLAEPRKSGEAGPGP

Target ORF information:

RefSeq Version	XM_011241678.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanylate cyclase 2d (Gucy2d), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241678.2

ORF Insert Sequence:

ATGGCGAGGG ATGTGGACTC TGTGCCCACA TCAGACACAG CAGGAACAAC AAGGCTTATC 
CATACATACC CTTCCTCAGG TCTGCAGCAG GGCTGTCACT TTGAAGGCCA GAACTGGACA 
GCACCACACT GGAAGACCTG CCTGCCCTGC CAGGGCCCGT GGAGACTCAC TGTCAGTCAT 
CTGAAGACTG TCTCTTCCAT ATCAGTCCTC TCTGTGGTAT TTTGGAGTGT CCTACTTTGG 
GCTGACTCCC TTTCCCTGTT AGCATGGGCA AGAGAGACCT TCACCCTTGG GGTGCTGGGT 
CCCTGGGACT GTGACCCCAT CTTTGCCCAG GCCCTCCCCA GCATAGCTAC CCAGCTGGCT 
GTAGATCAAG TTAATCAGGA TGCCTCACTG CTGCCAGGCT CACAGTTGGA TTTCAAGGTC 
CTCCCCACAG GCTGTGACAC TCCTCATGCC CTGGCCACAT TCGTGGCCCA CAAGAACATA 
GTGGCTGCTT TTGTAGGCCC TGTTAATCCT GGGTTCTGCT CAGCAGCAGC CCTGCTGGCC 
CAAGGCTGGG GCAAGTCCCT CTTCTCCTGG GCCTGTGAAG CTCCAGAGGG AGGAGGTGAC 
TTAGTGCCCA CTTTACCTTC TGCGGCCGAT GTGCTACTGT CTGTCATGAG ACACTTTGGC 
TGGGCTCGCT GGGCCATTGT GTCCTCTCAC CAGGACATCT GGGTAACCAC AGCCCAGCAG 
CTGGCCACTG CTTTCAGGAC TCATGGGCTG CCCATCGGAC TGGTGACCTC TTTGGGACCT 
GGAGAGAAGG GGGCCACAGA GGTTTGCAAG CAGCTCCACA GTGTTCATGG TCTGAAAATT 
GTGGTTCTGT GCATGCACTC GGCGCTGCTT GGAGGCCTGG AGCAGACCAC CCTGCTGCAC 
TGTGCCTGGG AGGAGGGCCT CACAGACGGA AGGCTGGTCT TCCTGCCCTA CGACACGCTG 
CTCTTTGCCC TGCCCTATGG AAACCGCTCC TACCTGGTCC TGGATGACCA TGGGCCCCTT 
CAGGAAGCCT ATGACGCAGT ACTCACTGTC AGTCTGGAGT CCAGTCCTGA GAGCCACGCC 
TTCACTGCTA CCGAGATGAG TGGAGGGGCA ACTGCCAACT TGGAGCCAGA GCAGGTGTCC 
CCACTCTTTG GAACTATCTA TGATGCCGTC ATCCTGTTGG CCCATGCCCT GAACCGATCT 
GAGACCCATG GAGCGGGGCT CTCAGGGGCT CACTTAGGGG ACCACGTAAG AGCTCTTGAT 
GTGGCTGGTT TTAGCCAGAG AATCCGAACA GATGGGAAAG GCAGAAGGCT AGCCCAATAT 
GTCATCCTGG ACACAGATGG TGAAGGAAGC CAGTTGGTTC CTACCCACAT TCTGGACACA 
AGCACATGGC AGGTGCAGCC TCTGGGAAAG CCTATACACT TTCCTGGGGG GAGCCCTCCA 
GCCCATGACG CCAGCTGCTG GTTCGACCCC AACACACTAT GCATCAGAGG TGTGCAGCCC 
CTGGGCAGCC TCCTGACTCT GACGATAGCC TGTGTCCTGG CACTGGTTGG TGGATTCCTT 
GCTTACTTCA TCAGGTTAGG CCTCCAGCAG CTGCGGCTGT TGCGGGGCCC CCATCGGATC 
CTGCTGACAT CTCAGGAGCT CACCTTCCTC CAGCGGACCC CCAGCCGGAG GAGGCCACAT 
GTGGACAGCG GCAGTGAGTC AAGAAGTGTG GTGGATGGTG GAAGTCCACG GTCGGTGACC 
CAGGGGTCAG CAAGGAGCCT ACCAGCCTTC CTGGAGCACA CCAACGTGGC CCTGTACCAG 
GGAGAGTGGG TATGGCTGAA GAAGTTTGAA GCAGGCGTGG CTCCTGATCT TCGGCCAAGT 
AGCCTTAGCT TCCTGAGAAA GTTGCGGGAG ATGCGGCATG AGAATGTTAC TGCCTTCCTG 
GGCCTCTTTG TGGGCCCTGG GGTCAGTGCA ATGGTGCTGG AGCACTGTGC CCGTGGCAGC 
CTGGAGGACC TGCTGCAGAA TGAGAACCTG AGGCTAGACT GGACCTTCAA GGCCTCCTTA 
CTGTTGGATC TGATCCGAGG TTTGCGGTAT CTGCACCATC GGCGCTTCCC CCACGGGCGC 
CTCAAGTCCA GGAACTGTGT GGTGGACACT CGCTTTGTGC TCAAGATCAC TGATCATGGC 
TATGCAGAGT TCCTGGAGTC TCACTGTTCT TCCAGGCCCC AGCCAGCCCC AGAAGAGCTT 
CTGTGGACGG CTCCTGAGCT GCTGCGGGGG CCTGGGAAGG CCACCTTCAA AGGTGATGTT 
TTCAGCTTGG CCATCATCCT GCAGGAGGTA CTGACCCGAG ACCCACCCTA CTGCTCCTGG 
GGACTCTCAG CAGAAGAGAT CATCCGGAAG GTGGCATCTC CCCCTCCTCT GTGCCGGCCA 
CTGGTGTCCC CTGACCAGGG TCCCCTCGAG TGTATCCAGT TGATGCAGCT ATGCTGGGAG 
GAAGCTCCAG ATGACAGGCC AAGCTTGGAC CAGATCTACA CACAGTTCAA AAGCATCAAC 
CAAGGCAAGA AGACAAGTGT TGTAGACTCC ATGCTGCGGA TGCTGGAGAA GTATTCCGAA 
AGCCTGGAAG ATCTGGTCCA GGAGCGGACT GAGGAGCTGG AACTGGAGAG GCGGAAGACA 
GAGAGGCTGC TCTCGCAGAT GCTCCCTCCG TCTGTCGCCC ATGCTCTAAA GATGGGGACA 
ACAGTGGAGC CCGAGTACTT CGACCAGGTC ACCATCTATT TCAGTGACAT CGTGGGCTTC 
ACCACCATCT CAGCCTTGAG TGAGCCCATT GAGGTGGTGG GCTTCCTCAA TGATCTCTAC 
ACGCTGTTTG ATGCTGTTCT CGACAGCCAT GATGTGTATA AGGTGGAGAC CATAGGGGAT 
GCCTACATGG TGGCTTCTGG TCTCCCTCGG CGCAATGGAA ATCGGCACGC TGCTGAGATC 
GCCAACCTGG CCCTGGACAT CCTTAGCTAT GCAGGCAACT TTCGGATGAG GCATGCACCC 
GATGTACCCA TCCGTGTCAG GGCAGGTCTG CATTCAGGAC CCTGTGTGGC AGGTGTTGTG 
GGTCTCACCA TGCCTCGGTA CTGCCTCTTT GGGGACACCG TCAACACTGC CTCTAGGATG 
GAGTCCACTG GGCTGCCTTA CAGGATCCAT GTCAGTCAAA GCACTGTCCA GGCCCTGCTC 
AGCCTTGATG AAGGCTACAA AATTGATGTC AGAGGTCAGA CTGAACTGAA GGGGAAGGGC 
TTGGAGGAGA CCTACTGGCT GACAGGGAAG GTAGGATTCT GCAGACCCCT GCCTACACCT 
CTGTCTATCA AGCCTGGAGA CCCATGGCAG GACCGCATAA ACCAAGAAAT CCGGACTGGC 
TTTGCCAAAG CACGCCAGGG ACTGGCTGAG CCCAGAAAAT CAGGGGAGGC TGGGCCAGGT 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The R838S Mutation in Retinal Guanylyl Cyclase 1 (RetGC1) Alters Calcium Sensitivity of cGMP Synthesis in the Retina and Causes Blindness in Transgenic Mice.
The Journal of biological chemistry291(47)24504-24516(2016 Nov)
Dizhoor AM,Olshevskaya EV,Peshenko IV

A Family of non-GPCR Chemosensors Defines an Alternative Logic for Mammalian Olfaction.
Cell165(7)1734-1748(2016 Jun)
Greer PL,Bear DM,Lassance JM,Bloom ML,Tsukahara T,Pashkovski SL,Masuda FK,Nowlan AC,Kirchner R,Hoekstra HE,Datta SR

Functional study of two biochemically unusual mutations in
Molecular vision221342-1351(2016)
Boye SL,Olshevskaya EV,Peshenko IV,McCullough KT,Boye SE,Dizhoor AM

Retinal guanylyl cyclase isozyme 1 is the preferential in vivo target for constitutively active GCAP1 mutants causing congenital degeneration of photoreceptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience32(21)7208-17(2012 May)
Olshevskaya EV,Peshenko IV,Savchenko AB,Dizhoor AM

RD3, the protein associated with Leber congenital amaurosis type 12, is required for guanylate cyclase trafficking in photoreceptor cells.
Proceedings of the National Academy of Sciences of the United States of America107(49)21158-63(2010 Dec)
Azadi S,Molday LL,Molday RS

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Gucy2d cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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