Gnaq cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gnaq
Entrez Gene ID	14682
Full Name	guanine nucleotide binding protein, alpha q polypeptide
Synonyms	1110005L02Rik,6230401I02Rik,AA408290,AW060788,Dsk1,Dsk10,Galphaq,Gq,GqI
General protein information	Preferred Names guanine nucleotide binding protein, alpha q polypeptide Names guanine nucleotide-binding protein G(q) subunit alpha G alpha q guanine nucleotide-binding protein alpha-q
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19 A\|19 11.01 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008139.6	NP_032165.3	guanine nucleotide-binding protein G(q) subunit alpha
NM_008139.5	NP_032165.3	guanine nucleotide-binding protein G(q) subunit alpha

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	gnaq	NP_001138271.1
Xenopus tropicalis (tropical clawed frog)	gnaq	NP_001037982.1
Rattus norvegicus (Norway rat)	Gnaq	NP_112298.1
Gallus gallus (chicken)	GNAQ	NP_001026598.1
Canis lupus familiaris (dog)	GNAQ	NP_001003249.1
Pan troglodytes (chimpanzee)	GNAQ	XP_003312167.1
Macaca mulatta (Rhesus monkey)	GNAQ	XP_001100833.1
Bos taurus (cattle)	GNAQ	NP_001103472.1
Mus musculus (house mouse)	Gnaq	NP_032165.3
Homo sapiens (human)	GNAQ	NP_002063.2

Gene Ontology
Bibliography

Related articles in PubMed

Translating biased signaling in the ghrelin receptor system into differential in vivo functions.
Mende F, Hundahl C, Plouffe B, Skov LJ, Sivertsen B, Madsen AN, Lückmann M, Diep TA, Offermanns S, Frimurer TM, Bouvier M, Holst B
Proceedings of the National Academy of Sciences of the United States of America115(43)E10255-E10264(2018 10)

PIP
Harraz OF, Longden TA, Hill-Eubanks D, Nelson MT
eLife7(2018 08)

The role of striatal Gα
Lee KW, Kim K, Kim HC, Lee SY, Jang CG
Behavioural brain research34666-72(2018 07)

Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.
Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF, Lin A, Mo H, Lu YJ, Li MJ, Kong W, Chung KY, Yi F, Li JY, Qin YY, Li J, Thomsen ARB, Kahsai AW, Chen ZJ, Xu ZG, Liu M, Li D, Yu X, Sun JP
eLife7(2018 02)

Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis.
Müller-Fielitz H, Stahr M, Bernau M, Richter M, Abele S, Krajka V, Benzin A, Wenzel J, Kalies K, Mittag J, Heuer H, Offermanns S, Schwaninger M
Nature communications8(1)484(2017 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Gnaq gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gnaq cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19275	NM_008139.6 Latest version!	Mus musculus guanine nucleotide binding protein, alpha q polypeptide (Gnaq), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$188.30 $269.00
View Old Accession Versions >>
OMu19275	NM_008139.5	Mus musculus guanine nucleotide binding protein, alpha q polypeptide (Gnaq), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gnaq ( NM_008139.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032165.3 Mus musculus guanine nucleotide binding protein, alpha q polypeptide (Gnaq), mRNA.

Price & Availability↑

CloneID	OMu19275
Clone ID Related Accession (Same CDS sequence)	NM_008139.6 , NM_008139.5
Accession Version	NM_008139.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1512835200000
Organism	Mus musculus(house mouse)
Product	guanine nucleotide-binding protein G(q) subunit alpha
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC102062.9, AC125202.3 and AC126031.2. On Apr 27, 2007 this sequence version replaced NM_008139.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK147393.1, SRR1660819.168855.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGACTCTGG AGTCCATCAT GGCGTGCTGC CTGAGCGAGG AGGCCAAGGA AGCCCGGAGG 
ATCAACGACG AGATCGAGCG GCAGCTGCGC AGGGACAAGC GCGACGCCCG CCGGGAGCTC 
AAGCTGCTGC TGCTGGGGAC AGGGGAGAGT GGCAAGAGCA CCTTCATCAA GCAGATGAGG 
ATCATCCACG GGTCGGGCTA CTCTGACGAA GACAAGCGCG GCTTCACCAA GCTGGTGTAT 
CAGAACATCT TCACGGCCAT GCAGGCCATG ATCAGAGCGA TGGACACGCT CAAGATCCCA 
TACAAGTATG AACACAATAA GGCTCATGCA CAATTGGTTC GAGAGGTTGA TGTGGAGAAG 
GTGTCTGCTT TTGAGAATCC ATATGTAGAT GCAATAAAGA GCTTGTGGAA TGATCCTGGA 
ATCCAGGAGT GCTACGACAG ACGACGGGAA TATCAGTTAT CTGACTCTAC CAAATACTAT 
CTGAATGACT TGGACCGTGT AGCCGACCCT TCCTATCTGC CTACACAACA AGACGTGCTT 
AGAGTTCGAG TCCCCACTAC AGGGATCATC GAATACCCCT TTGACTTACA AAGTGTCATT 
TTCAGAATGG TCGATGTAGG GGGCCAAAGG TCAGAGAGAA GAAAATGGAT ACACTGCTTT 
GAAAATGTCA CCTCCATCAT GTTTCTAGTA GCGCTTAGCG AATATGATCA AGTTCTTGTG 
GAGTCAGACA ATGAGAACCG CATGGAGGAG AGCAAAGCAC TCTTTAGAAC AATTATCACC 
TACCCCTGGT TCCAGAACTC CTCTGTGATT CTGTTCTTAA ACAAGAAAGA TCTTCTAGAG 
GAGAAAATCA TGTATTCCCA CCTAGTCGAC TACTTCCCAG AATATGATGG ACCCCAGAGA 
GATGCCCAGG CAGCTCGAGA ATTCATCCTG AAAATGTTCG TGGACCTGAA CCCCGACAGT 
GACAAAATCA TCTACTCCCA CTTCACGTGC GCCACAGATA CCGAGAACAT CCGCTTCGTC 
TTTGCAGCCG TCAAGGACAC CATCCTGCAG CTGAACCTGA AGGAGTACAA TCTGGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032165.3
CDS	496..1575
Translation	MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV

Target ORF information:

RefSeq Version	NM_008139.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanine nucleotide binding protein, alpha q polypeptide (Gnaq), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008139.5

ORF Insert Sequence:

ATGACTCTGG AGTCCATCAT GGCGTGCTGC CTGAGCGAGG AGGCCAAGGA AGCCCGGAGG 
ATCAACGACG AGATCGAGCG GCAGCTGCGC AGGGACAAGC GCGACGCCCG CCGGGAGCTC 
AAGCTGCTGC TGCTGGGGAC AGGGGAGAGT GGCAAGAGCA CCTTCATCAA GCAGATGAGG 
ATCATCCACG GGTCGGGCTA CTCTGACGAA GACAAGCGCG GCTTCACCAA GCTGGTGTAT 
CAGAACATCT TCACGGCCAT GCAGGCCATG ATCAGAGCGA TGGACACGCT CAAGATCCCA 
TACAAGTATG AACACAATAA GGCTCATGCA CAATTGGTTC GAGAGGTTGA TGTGGAGAAG 
GTGTCTGCTT TTGAGAATCC ATATGTAGAT GCAATAAAGA GCTTGTGGAA TGATCCTGGA 
ATCCAGGAGT GCTACGACAG ACGACGGGAA TATCAGTTAT CTGACTCTAC CAAATACTAT 
CTGAATGACT TGGACCGTGT AGCCGACCCT TCCTATCTGC CTACACAACA AGACGTGCTT 
AGAGTTCGAG TCCCCACTAC AGGGATCATC GAATACCCCT TTGACTTACA AAGTGTCATT 
TTCAGAATGG TCGATGTAGG GGGCCAAAGG TCAGAGAGAA GAAAATGGAT ACACTGCTTT 
GAAAATGTCA CCTCCATCAT GTTTCTAGTA GCGCTTAGCG AATATGATCA AGTTCTTGTG 
GAGTCAGACA ATGAGAACCG CATGGAGGAG AGCAAAGCAC TCTTTAGAAC AATTATCACC 
TACCCCTGGT TCCAGAACTC CTCTGTGATT CTGTTCTTAA ACAAGAAAGA TCTTCTAGAG 
GAGAAAATCA TGTATTCCCA CCTAGTCGAC TACTTCCCAG AATATGATGG ACCCCAGAGA 
GATGCCCAGG CAGCTCGAGA ATTCATCCTG AAAATGTTCG TGGACCTGAA CCCCGACAGT 
GACAAAATCA TCTACTCCCA CTTCACGTGC GCCACAGATA CCGAGAACAT CCGCTTCGTC 
TTTGCAGCCG TCAAGGACAC CATCCTGCAG CTGAACCTGA AGGAGTACAA TCTGGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gnaq ( NM_008139.6 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032165.3 Mus musculus guanine nucleotide binding protein, alpha q polypeptide (Gnaq), mRNA.

Price & Availability↑

CloneID	OMu19275
Clone ID Related Accession (Same CDS sequence)	NM_008139.6 , NM_008139.5
Accession Version	NM_008139.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Mus musculus(house mouse)
Product	guanine nucleotide-binding protein G(q) subunit alpha
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC102062.9, AC125202.3 and AC126031.2. On Jul 21, 2018 this sequence version replaced NM_008139.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK147393.1, SRR7974084.63.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTCTGG AGTCCATCAT GGCGTGCTGC CTGAGCGAGG AGGCCAAGGA AGCCCGGAGG 
ATCAACGACG AGATCGAGCG GCAGCTGCGC AGGGACAAGC GCGACGCCCG CCGGGAGCTC 
AAGCTGCTGC TGCTGGGGAC AGGGGAGAGT GGCAAGAGCA CCTTCATCAA GCAGATGAGG 
ATCATCCACG GGTCGGGCTA CTCTGACGAA GACAAGCGCG GCTTCACCAA GCTGGTGTAT 
CAGAACATCT TCACGGCCAT GCAGGCCATG ATCAGAGCGA TGGACACGCT CAAGATCCCA 
TACAAGTATG AACACAATAA GGCTCATGCA CAATTGGTTC GAGAGGTTGA TGTGGAGAAG 
GTGTCTGCTT TTGAGAATCC ATATGTAGAT GCAATAAAGA GCTTGTGGAA TGATCCTGGA 
ATCCAGGAGT GCTACGACAG ACGACGGGAA TATCAGTTAT CTGACTCTAC CAAATACTAT 
CTGAATGACT TGGACCGTGT AGCCGACCCT TCCTATCTGC CTACACAACA AGACGTGCTT 
AGAGTTCGAG TCCCCACTAC AGGGATCATC GAATACCCCT TTGACTTACA AAGTGTCATT 
TTCAGAATGG TCGATGTAGG GGGCCAAAGG TCAGAGAGAA GAAAATGGAT ACACTGCTTT 
GAAAATGTCA CCTCCATCAT GTTTCTAGTA GCGCTTAGCG AATATGATCA AGTTCTTGTG 
GAGTCAGACA ATGAGAACCG CATGGAGGAG AGCAAAGCAC TCTTTAGAAC AATTATCACC 
TACCCCTGGT TCCAGAACTC CTCTGTGATT CTGTTCTTAA ACAAGAAAGA TCTTCTAGAG 
GAGAAAATCA TGTATTCCCA CCTAGTCGAC TACTTCCCAG AATATGATGG ACCCCAGAGA 
GATGCCCAGG CAGCTCGAGA ATTCATCCTG AAAATGTTCG TGGACCTGAA CCCCGACAGT 
GACAAAATCA TCTACTCCCA CTTCACGTGC GCCACAGATA CCGAGAACAT CCGCTTCGTC 
TTTGCAGCCG TCAAGGACAC CATCCTGCAG CTGAACCTGA AGGAGTACAA TCTGGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032165.3
CDS	643..1722
Translation	MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV

Target ORF information:

RefSeq Version	NM_008139.6
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanine nucleotide binding protein, alpha q polypeptide (Gnaq), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008139.6

ORF Insert Sequence:

ATGACTCTGG AGTCCATCAT GGCGTGCTGC CTGAGCGAGG AGGCCAAGGA AGCCCGGAGG 
ATCAACGACG AGATCGAGCG GCAGCTGCGC AGGGACAAGC GCGACGCCCG CCGGGAGCTC 
AAGCTGCTGC TGCTGGGGAC AGGGGAGAGT GGCAAGAGCA CCTTCATCAA GCAGATGAGG 
ATCATCCACG GGTCGGGCTA CTCTGACGAA GACAAGCGCG GCTTCACCAA GCTGGTGTAT 
CAGAACATCT TCACGGCCAT GCAGGCCATG ATCAGAGCGA TGGACACGCT CAAGATCCCA 
TACAAGTATG AACACAATAA GGCTCATGCA CAATTGGTTC GAGAGGTTGA TGTGGAGAAG 
GTGTCTGCTT TTGAGAATCC ATATGTAGAT GCAATAAAGA GCTTGTGGAA TGATCCTGGA 
ATCCAGGAGT GCTACGACAG ACGACGGGAA TATCAGTTAT CTGACTCTAC CAAATACTAT 
CTGAATGACT TGGACCGTGT AGCCGACCCT TCCTATCTGC CTACACAACA AGACGTGCTT 
AGAGTTCGAG TCCCCACTAC AGGGATCATC GAATACCCCT TTGACTTACA AAGTGTCATT 
TTCAGAATGG TCGATGTAGG GGGCCAAAGG TCAGAGAGAA GAAAATGGAT ACACTGCTTT 
GAAAATGTCA CCTCCATCAT GTTTCTAGTA GCGCTTAGCG AATATGATCA AGTTCTTGTG 
GAGTCAGACA ATGAGAACCG CATGGAGGAG AGCAAAGCAC TCTTTAGAAC AATTATCACC 
TACCCCTGGT TCCAGAACTC CTCTGTGATT CTGTTCTTAA ACAAGAAAGA TCTTCTAGAG 
GAGAAAATCA TGTATTCCCA CCTAGTCGAC TACTTCCCAG AATATGATGG ACCCCAGAGA 
GATGCCCAGG CAGCTCGAGA ATTCATCCTG AAAATGTTCG TGGACCTGAA CCCCGACAGT 
GACAAAATCA TCTACTCCCA CTTCACGTGC GCCACAGATA CCGAGAACAT CCGCTTCGTC 
TTTGCAGCCG TCAAGGACAC CATCCTGCAG CTGAACCTGA AGGAGTACAA TCTGGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Translating biased signaling in the ghrelin receptor system into differential in vivo functions.
Proceedings of the National Academy of Sciences of the United States of America115(43)E10255-E10264(2018 10)
Mende F,Hundahl C,Plouffe B,Skov LJ,Sivertsen B,Madsen AN,Lückmann M,Diep TA,Offermanns S,Frimurer TM,Bouvier M,Holst B

PIP
eLife7(2018 08)
Harraz OF,Longden TA,Hill-Eubanks D,Nelson MT

The role of striatal Gα
Behavioural brain research34666-72(2018 07)
Lee KW,Kim K,Kim HC,Lee SY,Jang CG

Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.
eLife7(2018 02)
Zhang DL,Sun YJ,Ma ML,Wang YJ,Lin H,Li RR,Liang ZL,Gao Y,Yang Z,He DF,Lin A,Mo H,Lu YJ,Li MJ,Kong W,Chung KY,Yi F,Li JY,Qin YY,Li J,Thomsen ARB,Kahsai AW,Chen ZJ,Xu ZG,Liu M,Li D,Yu X,Sun JP

Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis.
Nature communications8(1)484(2017 09)
Müller-Fielitz H,Stahr M,Bernau M,Richter M,Abele S,Krajka V,Benzin A,Wenzel J,Kalies K,Mittag J,Heuer H,Offermanns S,Schwaninger M

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Gnaq cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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