Egfr cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Egfr
Entrez Gene ID	13649
Full Name	epidermal growth factor receptor
Synonyms	9030024J15Rik,AI552599,Erbb,Errb1,Errp,Wa5,wa-2,wa2
General protein information	Preferred Names epidermal growth factor receptor Names epidermal growth factor receptor avian erythroblastic leukemia viral (v-erb-b) oncogene homolog waved 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11 A2\|11 9.41 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_007912.4	NP_031938.1	epidermal growth factor receptor isoform 2 precursor
NM_207655.2	NP_997538.1	epidermal growth factor receptor isoform 1 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	EGFR	XP_533073.3
Danio rerio (zebrafish)	egfra	NP_919405.1
Pan troglodytes (chimpanzee)	EGFR	XP_519102.3
Bos taurus (cattle)	EGFR	XP_002696936.2
Mus musculus (house mouse)	Egfr	NP_997538.1
Gallus gallus (chicken)	EGFR	NP_990828.2
Macaca mulatta (Rhesus monkey)	EGFR	XP_001107305.1
Rattus norvegicus (Norway rat)	Egfr	NP_113695.1
Homo sapiens (human)	EGFR	NP_005219.2
Xenopus tropicalis (tropical clawed frog)	egfr	XP_002939960.2

Gene Ontology
Bibliography

Related articles in PubMed

Deficiency in the secreted protein Semaphorin3d causes abnormal parathyroid development in mice.
Singh A, Mia MM, Cibi DM, Arya AK, Bhadada SK, Singh MK
The Journal of biological chemistry294(21)8336-8347(2019 05)

A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation.
Minutti CM, Modak RV, Macdonald F, Li F, Smyth DJ, Dorward DA, Blair N, Husovsky C, Muir A, Giampazolias E, Dobie R, Maizels RM, Kendall TJ, Griggs DW, Kopf M, Henderson NC, Zaiss DM
Immunity50(3)645-654.e6(2019 03)

Epidermal growth factor receptor inhibition attenuates non-alcoholic fatty liver disease in diet-induced obese mice.
Choung S, Kim JM, Joung KH, Lee ES, Kim HJ, Ku BJ
PloS one14(2)e0210828(2019)

Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Starossom SC, Campo Garcia J, Woelfle T, Romero-Suarez S, Olah M, Watanabe F, Cao L, Yeste A, Tukker JJ, Quintana FJ, Imitola J, Witzel F, Schmitz D, Morkel M, Paul F, Infante-Duarte C, Khoury SJ
Nature communications10(1)217(2019 01)

Disruption of the Interaction of RAS with PI 3-Kinase Induces Regression of EGFR-Mutant-Driven Lung Cancer.
Murillo MM, Rana S, Spencer-Dene B, Nye E, Stamp G, Downward J
Cell reports25(13)3545-3553.e2(2018 12)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Egfr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Egfr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu22406	NM_007912.4 Latest version!	Mus musculus epidermal growth factor receptor (Egfr), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu22295	NM_207655.2 Latest version!	Mus musculus epidermal growth factor receptor (Egfr), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Egfr ( NM_007912.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031938.1 Mus musculus epidermal growth factor receptor (Egfr), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu22406
Clone ID Related Accession (Same CDS sequence)	NM_007912.4
Accession Version	NM_007912.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Mus musculus(house mouse)
Product	epidermal growth factor receptor isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK004883.1 and AK004944.1. On Mar 24, 2006 this sequence version replaced NM_007912.3. Transcript Variant: This variant (2) lacks several exons and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC023729.1, AK004944.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END##

ATGCGACCCT CAGGGACCGC GAGAACCACA CTGCTGGTGT TGCTGACCGC GCTCTGCGCC 
GCAGGTGGGG CGTTGGAGGA AAAGAAAGTC TGCCAAGGCA CAAGTAACAG GCTCACCCAA 
CTGGGCACTT TTGAAGACCA CTTTCTGAGC CTGCAGAGGA TGTACAACAA CTGTGAAGTG 
GTCCTTGGGA ACTTGGAAAT TACCTATGTG CAAAGGAATT ACGACCTTTC CTTCTTAAAG 
ACCATCCAGG AGGTGGCCGG CTATGTCCTC ATTGCCCTCA ACACCGTGGA GAGAATCCCT 
TTGGAGAACC TGCAGATCAT CAGGGGAAAT GCTCTTTATG AAAACACCTA TGCCTTAGCC 
ATCCTGTCCA ACTATGGGAC AAACAGAACT GGGCTTAGGG AACTGCCCAT GCGGAACTTA 
CAGGAAATCC TGATTGGTGC TGTGCGATTC AGCAACAACC CCATCCTCTG CAATATGGAT 
ACTATCCAGT GGAGGGACAT CGTCCAAAAC GTCTTTATGA GCAACATGTC AATGGACTTA 
CAGAGCCATC CGAGCAGTTG CCCCAAATGT GATCCAAGCT GTCCCAATGG AAGCTGCTGG 
GGAGGAGGAG AGGAGAACTG CCAGAAATTG ACCAAAATCA TCTGTGCCCA GCAATGTTCC 
CATCGCTGTC GTGGCAGGTC CCCCAGTGAC TGCTGCCACA ACCAATGTGC TGCGGGGTGT 
ACAGGGCCCC GAGAGAGTGA CTGTCTGGTC TGCCAAAAGT TCCAAGATGA GGCCACATGC 
AAAGACACCT GCCCACCACT CATGCTGTAC AACCCCACCA CCTATCAGAT GGATGTCAAC 
CCTGAAGGGA AGTACAGCTT TGGTGCCACC TGTGTGAAGA AGTGCCCCCG AAACTACGTG 
GTGACAGATC ATGGCTCATG TGTCCGAGCC TGTGGGCCTG ACTACTACGA AGTGGAAGAA 
GATGGCATCC GCAAGTGTAA AAAATGTGAT GGGCCCTGTC GCAAAGTTTG TAATGGCATA 
GGCATTGGTG AATTTAAAGA CACACTCTCC ATAAATGCTA CAAACATCAA ACACTTCAAA 
TACTGCACTG CCATCAGCGG GGACCTTCAC ATCCTGCCAG TGGCCTTTAA GGGGGATTCT 
TTCACGCGCA CTCCTCCTCT AGACCCACGA GAACTAGAAA TTCTAAAAAC CGTAAAGGAA 
ATAACAGGCT TTTTGCTGAT TCAGGCTTGG CCTGATAACT GGACTGACCT CCATGCTTTC 
GAGAACCTAG AAATAATACG TGGCAGAACA AAGCAACATG GTCAGTTTTC TTTGGCGGTC 
GTTGGCCTGA ACATCACATC ACTGGGGCTG CGTTCCCTCA AGGAGATCAG TGATGGGGAT 
GTGATCATTT CTGGAAACCG AAATTTGTGC TACGCAAACA CAATAAACTG GAAAAAACTC 
TTCGGGACAC CCAATCAGAA AACCAAAATC ATGAACAACA GAGCTGAGAA AGACTGCAAG 
GCCGTGAACC ACGTCTGCAA TCCTTTATGC TCCTCGGAAG GCTGCTGGGG CCCTGAGCCC 
AGGGACTGTG TCTCCTGCCA GAATGTGAGC AGAGGCAGGG AGTGCGTGGA GAAATGCAAC 
ATCCTGGAGG GGGAACCAAG GGAGTTTGTG GAAAATTCTG AATGCATCCA GTGCCATCCA 
GAATGTCTGC CCCAGGCCAT GAACATCACC TGTACAGGCA GGGGACCAGA CAACTGCATC 
CAGTGTGCCC ACTACATTGA TGGCCCACAC TGTGTCAAGA CCTGCCCAGC TGGCATCATG 
GGAGAGAACA ACACTCTGGT CTGGAAGTAT GCAGATGCCA ATAATGTCTG CCACCTATGC 
CACGCCAACT GTACCTATGG ATGTGCTGGG CCAGGTCTTC AAGGATGTGA AGTGTGGCCA 
TCTGGGTACG TTCAATGGCA GTGGATCTTA AAGACCTTTT GGATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031938.1
CDS	281..2248
Translation	MRPSGTARTTLLVLLTALCAAGGALEEKKVCQGTSNRLTQLGTFEDHFLSLQRMYNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALYENTYALAILSNYGTNRTGLRELPMRNLQEILIGAVRFSNNPILCNMDTIQWRDIVQNVFMSNMSMDLQSHPSSCPKCDPSCPNGSCWGGGEENCQKLTKIICAQQCSHRCRGRSPSDCCHNQCAAGCTGPRESDCLVCQKFQDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVEEDGIRKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFKGDSFTRTPPLDPRELEILKTVKEITGFLLIQAWPDNWTDLHAFENLEIIRGRTKQHGQFSLAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFGTPNQKTKIMNNRAEKDCKAVNHVCNPLCSSEGCWGPEPRDCVSCQNVSRGRECVEKCNILEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGIMGENNTLVWKYADANNVCHLCHANCTYGCAGPGLQGCEVWPSGYVQWQWILKTFWI

Target ORF information:

RefSeq Version	NM_007912.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus epidermal growth factor receptor (Egfr), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007912.4

ORF Insert Sequence:

ATGCGACCCT CAGGGACCGC GAGAACCACA CTGCTGGTGT TGCTGACCGC GCTCTGCGCC 
GCAGGTGGGG CGTTGGAGGA AAAGAAAGTC TGCCAAGGCA CAAGTAACAG GCTCACCCAA 
CTGGGCACTT TTGAAGACCA CTTTCTGAGC CTGCAGAGGA TGTACAACAA CTGTGAAGTG 
GTCCTTGGGA ACTTGGAAAT TACCTATGTG CAAAGGAATT ACGACCTTTC CTTCTTAAAG 
ACCATCCAGG AGGTGGCCGG CTATGTCCTC ATTGCCCTCA ACACCGTGGA GAGAATCCCT 
TTGGAGAACC TGCAGATCAT CAGGGGAAAT GCTCTTTATG AAAACACCTA TGCCTTAGCC 
ATCCTGTCCA ACTATGGGAC AAACAGAACT GGGCTTAGGG AACTGCCCAT GCGGAACTTA 
CAGGAAATCC TGATTGGTGC TGTGCGATTC AGCAACAACC CCATCCTCTG CAATATGGAT 
ACTATCCAGT GGAGGGACAT CGTCCAAAAC GTCTTTATGA GCAACATGTC AATGGACTTA 
CAGAGCCATC CGAGCAGTTG CCCCAAATGT GATCCAAGCT GTCCCAATGG AAGCTGCTGG 
GGAGGAGGAG AGGAGAACTG CCAGAAATTG ACCAAAATCA TCTGTGCCCA GCAATGTTCC 
CATCGCTGTC GTGGCAGGTC CCCCAGTGAC TGCTGCCACA ACCAATGTGC TGCGGGGTGT 
ACAGGGCCCC GAGAGAGTGA CTGTCTGGTC TGCCAAAAGT TCCAAGATGA GGCCACATGC 
AAAGACACCT GCCCACCACT CATGCTGTAC AACCCCACCA CCTATCAGAT GGATGTCAAC 
CCTGAAGGGA AGTACAGCTT TGGTGCCACC TGTGTGAAGA AGTGCCCCCG AAACTACGTG 
GTGACAGATC ATGGCTCATG TGTCCGAGCC TGTGGGCCTG ACTACTACGA AGTGGAAGAA 
GATGGCATCC GCAAGTGTAA AAAATGTGAT GGGCCCTGTC GCAAAGTTTG TAATGGCATA 
GGCATTGGTG AATTTAAAGA CACACTCTCC ATAAATGCTA CAAACATCAA ACACTTCAAA 
TACTGCACTG CCATCAGCGG GGACCTTCAC ATCCTGCCAG TGGCCTTTAA GGGGGATTCT 
TTCACGCGCA CTCCTCCTCT AGACCCACGA GAACTAGAAA TTCTAAAAAC CGTAAAGGAA 
ATAACAGGCT TTTTGCTGAT TCAGGCTTGG CCTGATAACT GGACTGACCT CCATGCTTTC 
GAGAACCTAG AAATAATACG TGGCAGAACA AAGCAACATG GTCAGTTTTC TTTGGCGGTC 
GTTGGCCTGA ACATCACATC ACTGGGGCTG CGTTCCCTCA AGGAGATCAG TGATGGGGAT 
GTGATCATTT CTGGAAACCG AAATTTGTGC TACGCAAACA CAATAAACTG GAAAAAACTC 
TTCGGGACAC CCAATCAGAA AACCAAAATC ATGAACAACA GAGCTGAGAA AGACTGCAAG 
GCCGTGAACC ACGTCTGCAA TCCTTTATGC TCCTCGGAAG GCTGCTGGGG CCCTGAGCCC 
AGGGACTGTG TCTCCTGCCA GAATGTGAGC AGAGGCAGGG AGTGCGTGGA GAAATGCAAC 
ATCCTGGAGG GGGAACCAAG GGAGTTTGTG GAAAATTCTG AATGCATCCA GTGCCATCCA 
GAATGTCTGC CCCAGGCCAT GAACATCACC TGTACAGGCA GGGGACCAGA CAACTGCATC 
CAGTGTGCCC ACTACATTGA TGGCCCACAC TGTGTCAAGA CCTGCCCAGC TGGCATCATG 
GGAGAGAACA ACACTCTGGT CTGGAAGTAT GCAGATGCCA ATAATGTCTG CCACCTATGC 
CACGCCAACT GTACCTATGG ATGTGCTGGG CCAGGTCTTC AAGGATGTGA AGTGTGGCCA 
TCTGGGTACG TTCAATGGCA GTGGATCTTA AAGACCTTTT GGATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Egfr ( NM_207655.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_997538.1 Mus musculus epidermal growth factor receptor (Egfr), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu22295
Clone ID Related Accession (Same CDS sequence)	NM_207655.2
Accession Version	NM_207655.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Mus musculus(house mouse)
Product	epidermal growth factor receptor isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK004883.1, AF275367.1, BQ553815.1, BY725722.1 and AK163338.1. On Mar 24, 2006 this sequence version replaced NM_207655.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF275367.1, X78987.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END##

ATGCGACCCT CAGGGACCGC GAGAACCACA CTGCTGGTGT TGCTGACCGC GCTCTGCGCC 
GCAGGTGGGG CGTTGGAGGA AAAGAAAGTC TGCCAAGGCA CAAGTAACAG GCTCACCCAA 
CTGGGCACTT TTGAAGACCA CTTTCTGAGC CTGCAGAGGA TGTACAACAA CTGTGAAGTG 
GTCCTTGGGA ACTTGGAAAT TACCTATGTG CAAAGGAATT ACGACCTTTC CTTCTTAAAG 
ACCATCCAGG AGGTGGCCGG CTATGTCCTC ATTGCCCTCA ACACCGTGGA GAGAATCCCT 
TTGGAGAACC TGCAGATCAT CAGGGGAAAT GCTCTTTATG AAAACACCTA TGCCTTAGCC 
ATCCTGTCCA ACTATGGGAC AAACAGAACT GGGCTTAGGG AACTGCCCAT GCGGAACTTA 
CAGGAAATCC TGATTGGTGC TGTGCGATTC AGCAACAACC CCATCCTCTG CAATATGGAT 
ACTATCCAGT GGAGGGACAT CGTCCAAAAC GTCTTTATGA GCAACATGTC AATGGACTTA 
CAGAGCCATC CGAGCAGTTG CCCCAAATGT GATCCAAGCT GTCCCAATGG AAGCTGCTGG 
GGAGGAGGAG AGGAGAACTG CCAGAAATTG ACCAAAATCA TCTGTGCCCA GCAATGTTCC 
CATCGCTGTC GTGGCAGGTC CCCCAGTGAC TGCTGCCACA ACCAATGTGC TGCGGGGTGT 
ACAGGGCCCC GAGAGAGTGA CTGTCTGGTC TGCCAAAAGT TCCAAGATGA GGCCACATGC 
AAAGACACCT GCCCACCACT CATGCTGTAC AACCCCACCA CCTATCAGAT GGATGTCAAC 
CCTGAAGGGA AGTACAGCTT TGGTGCCACC TGTGTGAAGA AGTGCCCCCG AAACTACGTG 
GTGACAGATC ATGGCTCATG TGTCCGAGCC TGTGGGCCTG ACTACTACGA AGTGGAAGAA 
GATGGCATCC GCAAGTGTAA AAAATGTGAT GGGCCCTGTC GCAAAGTTTG TAATGGCATA 
GGCATTGGTG AATTTAAAGA CACACTCTCC ATAAATGCTA CAAACATCAA ACACTTCAAA 
TACTGCACTG CCATCAGCGG GGACCTTCAC ATCCTGCCAG TGGCCTTTAA GGGGGATTCT 
TTCACGCGCA CTCCTCCTCT AGACCCACGA GAACTAGAAA TTCTAAAAAC CGTAAAGGAA 
ATAACAGGCT TTTTGCTGAT TCAGGCTTGG CCTGATAACT GGACTGACCT CCATGCTTTC 
GAGAACCTAG AAATAATACG TGGCAGAACA AAGCAACATG GTCAGTTTTC TTTGGCGGTC 
GTTGGCCTGA ACATCACATC ACTGGGGCTG CGTTCCCTCA AGGAGATCAG TGATGGGGAT 
GTGATCATTT CTGGAAACCG AAATTTGTGC TACGCAAACA CAATAAACTG GAAAAAACTC 
TTCGGGACAC CCAATCAGAA AACCAAAATC ATGAACAACA GAGCTGAGAA AGACTGCAAG 
GCCGTGAACC ACGTCTGCAA TCCTTTATGC TCCTCGGAAG GCTGCTGGGG CCCTGAGCCC 
AGGGACTGTG TCTCCTGCCA GAATGTGAGC AGAGGCAGGG AGTGCGTGGA GAAATGCAAC 
ATCCTGGAGG GGGAACCAAG GGAGTTTGTG GAAAATTCTG AATGCATCCA GTGCCATCCA 
GAATGTCTGC CCCAGGCCAT GAACATCACC TGTACAGGCA GGGGACCAGA CAACTGCATC 
CAGTGTGCCC ACTACATTGA TGGCCCACAC TGTGTCAAGA CCTGCCCAGC TGGCATCATG 
GGAGAGAACA ACACTCTGGT CTGGAAGTAT GCAGATGCCA ATAATGTCTG CCACCTATGC 
CACGCCAACT GTACCTATGG ATGTGCTGGG CCAGGTCTTC AAGGATGTGA AGTGTGGCCA 
TCTGGGCCAA AGATACCATC TATTGCCACT GGGATTGTGG GTGGCCTCCT CTTCATAGTG 
GTGGTGGCCC TTGGGATTGG CCTATTCATG CGAAGACGTC ACATTGTTCG AAAGCGTACA 
CTACGCCGCC TGCTTCAAGA GAGAGAGCTC GTGGAACCTC TCACACCCAG CGGAGAAGCT 
CCAAACCAAG CCCACTTGAG GATATTAAAG GAAACAGAAT TCAAAAAGAT CAAAGTTCTG 
GGTTCGGGAG CATTTGGCAC AGTGTATAAG GGTCTCTGGA TCCCAGAAGG TGAGAAAGTA 
AAAATCCCGG TGGCCATCAA GGAGTTAAGA GAAGCCACAT CTCCAAAAGC CAACAAAGAA 
ATCCTTGACG AAGCCTATGT GATGGCTAGT GTGGACAACC CTCATGTATG CCGCCTCCTG 
GGCATCTGTC TGACCTCCAC TGTCCAGCTC ATTACACAGC TCATGCCCTA CGGTTGCCTC 
CTGGACTACG TCCGAGAACA CAAGGACAAC ATTGGCTCCC AGTACCTCCT CAACTGGTGT 
GTGCAGATTG CAAAGGGCAT GAACTACCTG GAAGATCGGC GTTTGGTGCA CCGTGACTTG 
GCAGCCAGGA ATGTACTGGT GAAGACACCA CAGCATGTCA AGATCACAGA TTTTGGGCTG 
GCCAAACTGC TTGGTGCTGA AGAGAAAGAA TATCATGCCG AGGGGGGCAA AGTGCCTATC 
AAGTGGATGG CTTTGGAATC AATTTTACAC CGAATTTATA CACACCAAAG TGATGTCTGG 
AGCTATGGTG TCACTGTGTG GGAACTGATG ACCTTTGGGT CCAAGCCTTA TGATGGAATC 
CCAGCAAGTG ACATCTCATC CATCCTAGAG AAAGGAGAGC GCCTTCCACA GCCACCTATC 
TGCACCATCG ATGTCTACAT GATCATGGTC AAGTGCTGGA TGATAGATGC TGATAGCCGC 
CCAAAGTTCC GAGAGTTGAT TCTTGAATTC TCCAAAATGG CCCGAGACCC ACAGCGCTAC 
CTTGTTATCC AGGGGGATGA AAGAATGCAT TTGCCAAGCC CTACAGACTC CAACTTTTAC 
CGAGCCCTGA TGGATGAAGA GGACATGGAG GATGTAGTTG ATGCTGATGA GTATCTTATC 
CCACAGCAAG GCTTCTTCAA CAGCCCGTCC ACGTCGAGGA CTCCCCTCTT GAGTTCTCTG 
AGTGCAACTA GCAACAATTC CACTGTGGCT TGCATTAATA GAAATGGGAG CTGCCGTGTC 
AAAGAAGACG CCTTCTTGCA GCGGTACAGC TCCGACCCCA CAGGTGCTGT AACAGAGGAC 
AACATAGATG ACGCATTCCT CCCTGTACCT GAATATGTAA ACCAATCTGT TCCCAAGAGG 
CCAGCAGGCT CTGTGCAGAA CCCTGTCTAT CACAATCAGC CCCTGCATCC AGCTCCTGGA 
AGAGACCTGC ATTATCAAAA TCCCCACAGC AATGCAGTGG GCAACCCTGA GTATCTCAAC 
ACTGCCCAGC CTACCTGTCT CAGTAGTGGG TTTAACAGCC CTGCACTCTG GATCCAGAAA 
GGCAGTCACC AAATGAGCCT AGACAACCCT GACTACCAGC AGGACTTCTT CCCCAAGGAA 
ACCAAGCCAA ATGGCATATT TAAGGGCCCC ACAGCTGAAA ATGCAGAGTA CCTACGGGTG 
GCACCTCCAA GCAGTGAGTT TATTGGAGCA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997538.1
CDS	281..3913
Translation	MRPSGTARTTLLVLLTALCAAGGALEEKKVCQGTSNRLTQLGTFEDHFLSLQRMYNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALYENTYALAILSNYGTNRTGLRELPMRNLQEILIGAVRFSNNPILCNMDTIQWRDIVQNVFMSNMSMDLQSHPSSCPKCDPSCPNGSCWGGGEENCQKLTKIICAQQCSHRCRGRSPSDCCHNQCAAGCTGPRESDCLVCQKFQDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVEEDGIRKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFKGDSFTRTPPLDPRELEILKTVKEITGFLLIQAWPDNWTDLHAFENLEIIRGRTKQHGQFSLAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFGTPNQKTKIMNNRAEKDCKAVNHVCNPLCSSEGCWGPEPRDCVSCQNVSRGRECVEKCNILEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGIMGENNTLVWKYADANNVCHLCHANCTYGCAGPGLQGCEVWPSGPKIPSIATGIVGGLLFIVVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASDISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLIPQQGFFNSPSTSRTPLLSSLSATSNNSTVACINRNGSCRVKEDAFLQRYSSDPTGAVTEDNIDDAFLPVPEYVNQSVPKRPAGSVQNPVYHNQPLHPAPGRDLHYQNPHSNAVGNPEYLNTAQPTCLSSGFNSPALWIQKGSHQMSLDNPDYQQDFFPKETKPNGIFKGPTAENAEYLRVAPPSSEFIGA

Target ORF information:

RefSeq Version	NM_207655.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus epidermal growth factor receptor (Egfr), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207655.2

ORF Insert Sequence:

ATGCGACCCT CAGGGACCGC GAGAACCACA CTGCTGGTGT TGCTGACCGC GCTCTGCGCC 
GCAGGTGGGG CGTTGGAGGA AAAGAAAGTC TGCCAAGGCA CAAGTAACAG GCTCACCCAA 
CTGGGCACTT TTGAAGACCA CTTTCTGAGC CTGCAGAGGA TGTACAACAA CTGTGAAGTG 
GTCCTTGGGA ACTTGGAAAT TACCTATGTG CAAAGGAATT ACGACCTTTC CTTCTTAAAG 
ACCATCCAGG AGGTGGCCGG CTATGTCCTC ATTGCCCTCA ACACCGTGGA GAGAATCCCT 
TTGGAGAACC TGCAGATCAT CAGGGGAAAT GCTCTTTATG AAAACACCTA TGCCTTAGCC 
ATCCTGTCCA ACTATGGGAC AAACAGAACT GGGCTTAGGG AACTGCCCAT GCGGAACTTA 
CAGGAAATCC TGATTGGTGC TGTGCGATTC AGCAACAACC CCATCCTCTG CAATATGGAT 
ACTATCCAGT GGAGGGACAT CGTCCAAAAC GTCTTTATGA GCAACATGTC AATGGACTTA 
CAGAGCCATC CGAGCAGTTG CCCCAAATGT GATCCAAGCT GTCCCAATGG AAGCTGCTGG 
GGAGGAGGAG AGGAGAACTG CCAGAAATTG ACCAAAATCA TCTGTGCCCA GCAATGTTCC 
CATCGCTGTC GTGGCAGGTC CCCCAGTGAC TGCTGCCACA ACCAATGTGC TGCGGGGTGT 
ACAGGGCCCC GAGAGAGTGA CTGTCTGGTC TGCCAAAAGT TCCAAGATGA GGCCACATGC 
AAAGACACCT GCCCACCACT CATGCTGTAC AACCCCACCA CCTATCAGAT GGATGTCAAC 
CCTGAAGGGA AGTACAGCTT TGGTGCCACC TGTGTGAAGA AGTGCCCCCG AAACTACGTG 
GTGACAGATC ATGGCTCATG TGTCCGAGCC TGTGGGCCTG ACTACTACGA AGTGGAAGAA 
GATGGCATCC GCAAGTGTAA AAAATGTGAT GGGCCCTGTC GCAAAGTTTG TAATGGCATA 
GGCATTGGTG AATTTAAAGA CACACTCTCC ATAAATGCTA CAAACATCAA ACACTTCAAA 
TACTGCACTG CCATCAGCGG GGACCTTCAC ATCCTGCCAG TGGCCTTTAA GGGGGATTCT 
TTCACGCGCA CTCCTCCTCT AGACCCACGA GAACTAGAAA TTCTAAAAAC CGTAAAGGAA 
ATAACAGGCT TTTTGCTGAT TCAGGCTTGG CCTGATAACT GGACTGACCT CCATGCTTTC 
GAGAACCTAG AAATAATACG TGGCAGAACA AAGCAACATG GTCAGTTTTC TTTGGCGGTC 
GTTGGCCTGA ACATCACATC ACTGGGGCTG CGTTCCCTCA AGGAGATCAG TGATGGGGAT 
GTGATCATTT CTGGAAACCG AAATTTGTGC TACGCAAACA CAATAAACTG GAAAAAACTC 
TTCGGGACAC CCAATCAGAA AACCAAAATC ATGAACAACA GAGCTGAGAA AGACTGCAAG 
GCCGTGAACC ACGTCTGCAA TCCTTTATGC TCCTCGGAAG GCTGCTGGGG CCCTGAGCCC 
AGGGACTGTG TCTCCTGCCA GAATGTGAGC AGAGGCAGGG AGTGCGTGGA GAAATGCAAC 
ATCCTGGAGG GGGAACCAAG GGAGTTTGTG GAAAATTCTG AATGCATCCA GTGCCATCCA 
GAATGTCTGC CCCAGGCCAT GAACATCACC TGTACAGGCA GGGGACCAGA CAACTGCATC 
CAGTGTGCCC ACTACATTGA TGGCCCACAC TGTGTCAAGA CCTGCCCAGC TGGCATCATG 
GGAGAGAACA ACACTCTGGT CTGGAAGTAT GCAGATGCCA ATAATGTCTG CCACCTATGC 
CACGCCAACT GTACCTATGG ATGTGCTGGG CCAGGTCTTC AAGGATGTGA AGTGTGGCCA 
TCTGGGCCAA AGATACCATC TATTGCCACT GGGATTGTGG GTGGCCTCCT CTTCATAGTG 
GTGGTGGCCC TTGGGATTGG CCTATTCATG CGAAGACGTC ACATTGTTCG AAAGCGTACA 
CTACGCCGCC TGCTTCAAGA GAGAGAGCTC GTGGAACCTC TCACACCCAG CGGAGAAGCT 
CCAAACCAAG CCCACTTGAG GATATTAAAG GAAACAGAAT TCAAAAAGAT CAAAGTTCTG 
GGTTCGGGAG CATTTGGCAC AGTGTATAAG GGTCTCTGGA TCCCAGAAGG TGAGAAAGTA 
AAAATCCCGG TGGCCATCAA GGAGTTAAGA GAAGCCACAT CTCCAAAAGC CAACAAAGAA 
ATCCTTGACG AAGCCTATGT GATGGCTAGT GTGGACAACC CTCATGTATG CCGCCTCCTG 
GGCATCTGTC TGACCTCCAC TGTCCAGCTC ATTACACAGC TCATGCCCTA CGGTTGCCTC 
CTGGACTACG TCCGAGAACA CAAGGACAAC ATTGGCTCCC AGTACCTCCT CAACTGGTGT 
GTGCAGATTG CAAAGGGCAT GAACTACCTG GAAGATCGGC GTTTGGTGCA CCGTGACTTG 
GCAGCCAGGA ATGTACTGGT GAAGACACCA CAGCATGTCA AGATCACAGA TTTTGGGCTG 
GCCAAACTGC TTGGTGCTGA AGAGAAAGAA TATCATGCCG AGGGGGGCAA AGTGCCTATC 
AAGTGGATGG CTTTGGAATC AATTTTACAC CGAATTTATA CACACCAAAG TGATGTCTGG 
AGCTATGGTG TCACTGTGTG GGAACTGATG ACCTTTGGGT CCAAGCCTTA TGATGGAATC 
CCAGCAAGTG ACATCTCATC CATCCTAGAG AAAGGAGAGC GCCTTCCACA GCCACCTATC 
TGCACCATCG ATGTCTACAT GATCATGGTC AAGTGCTGGA TGATAGATGC TGATAGCCGC 
CCAAAGTTCC GAGAGTTGAT TCTTGAATTC TCCAAAATGG CCCGAGACCC ACAGCGCTAC 
CTTGTTATCC AGGGGGATGA AAGAATGCAT TTGCCAAGCC CTACAGACTC CAACTTTTAC 
CGAGCCCTGA TGGATGAAGA GGACATGGAG GATGTAGTTG ATGCTGATGA GTATCTTATC 
CCACAGCAAG GCTTCTTCAA CAGCCCGTCC ACGTCGAGGA CTCCCCTCTT GAGTTCTCTG 
AGTGCAACTA GCAACAATTC CACTGTGGCT TGCATTAATA GAAATGGGAG CTGCCGTGTC 
AAAGAAGACG CCTTCTTGCA GCGGTACAGC TCCGACCCCA CAGGTGCTGT AACAGAGGAC 
AACATAGATG ACGCATTCCT CCCTGTACCT GAATATGTAA ACCAATCTGT TCCCAAGAGG 
CCAGCAGGCT CTGTGCAGAA CCCTGTCTAT CACAATCAGC CCCTGCATCC AGCTCCTGGA 
AGAGACCTGC ATTATCAAAA TCCCCACAGC AATGCAGTGG GCAACCCTGA GTATCTCAAC 
ACTGCCCAGC CTACCTGTCT CAGTAGTGGG TTTAACAGCC CTGCACTCTG GATCCAGAAA 
GGCAGTCACC AAATGAGCCT AGACAACCCT GACTACCAGC AGGACTTCTT CCCCAAGGAA 
ACCAAGCCAA ATGGCATATT TAAGGGCCCC ACAGCTGAAA ATGCAGAGTA CCTACGGGTG 
GCACCTCCAA GCAGTGAGTT TATTGGAGCA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Deficiency in the secreted protein Semaphorin3d causes abnormal parathyroid development in mice.
The Journal of biological chemistry294(21)8336-8347(2019 05)
Singh A,Mia MM,Cibi DM,Arya AK,Bhadada SK,Singh MK

A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation.
Immunity50(3)645-654.e6(2019 03)
Minutti CM,Modak RV,Macdonald F,Li F,Smyth DJ,Dorward DA,Blair N,Husovsky C,Muir A,Giampazolias E,Dobie R,Maizels RM,Kendall TJ,Griggs DW,Kopf M,Henderson NC,Zaiss DM

Epidermal growth factor receptor inhibition attenuates non-alcoholic fatty liver disease in diet-induced obese mice.
PloS one14(2)e0210828(2019)
Choung S,Kim JM,Joung KH,Lee ES,Kim HJ,Ku BJ

Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Nature communications10(1)217(2019 01)
Starossom SC,Campo Garcia J,Woelfle T,Romero-Suarez S,Olah M,Watanabe F,Cao L,Yeste A,Tukker JJ,Quintana FJ,Imitola J,Witzel F,Schmitz D,Morkel M,Paul F,Infante-Duarte C,Khoury SJ

Disruption of the Interaction of RAS with PI 3-Kinase Induces Regression of EGFR-Mutant-Driven Lung Cancer.
Cell reports25(13)3545-3553.e2(2018 12)
Murillo MM,Rana S,Spencer-Dene B,Nye E,Stamp G,Downward J

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Egfr cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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ORF Insert Sequence:

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