Chml cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Chml
Entrez Gene ID	12663
Full Name	choroideremia-like
Synonyms	AI450814,E030003F13Rik,REP-2,Rep2
General protein information	Preferred Names choroideremia-like Names rab proteins geranylgeranyltransferase component A 2 choroideraemia-like protein choroideremia-like protein rab escort protein-2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 H3\|1 81.7 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_021350.2	NP_067325.2	rab proteins geranylgeranyltransferase component A 2

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os01g0269100	NP_001042697.1
Canis lupus familiaris (dog)	CHML	XP_537217.1
Pan troglodytes (chimpanzee)	CHML	XP_514301.1
Bos taurus (cattle)	CHML	XP_005216928.1
Rattus norvegicus (Norway rat)	Chml	NP_001102994.1
Homo sapiens (human)	CHML	NP_001812.2
Mus musculus (house mouse)	Chml	NP_067325.2
Caenorhabditis elegans (roundworm)	rep-1	NP_001022928.1
Danio rerio (zebrafish)	chm	NP_982286.1
Arabidopsis thaliana (thale cress)	REP	NP_187306.2

Gene Ontology
Bibliography

Related articles in PubMed

Different structural organization of the encephalopsin gene in man and mouse.
Kasper G, Taudien S, Staub E, Mennerich D, Rieder M, Hinzmann B, Dahl E, Schwidetzky U, Rosenthal A, Rump A
Gene295(1)27-32(2002 Jul)

Localization of the Rab escort protein-2 (REP2) and inositol 1,4,5-trisphosphate 3-kinase (ITPKB) genes to mouse chromosome 1 by in situ hybridization and precision of the syntenic regions between mouse and human 1q42-q44.
Barrat FJ, Depetris D, Certain S, Mattei MG, de Saint Basile G
Genomics43(1)111-3(1997 Jul)

Mouse choroideremia gene mutation causes photoreceptor cell degeneration and is not transmitted through the female germline.
van den Hurk JA, Hendriks W, van de Pol DJ, Oerlemans F, Jaissle G, Rüther K, Kohler K, Hartmann J, Zrenner E, van Bokhoven H, Wieringa B, Ropers HH, Cremers FP
Human molecular genetics6(6)851-8(1997 Jun)

Genetic mapping of 20 novel expressed sequence tags from midgestation mouse embryos suggests chromosomal clustering.
Tchernev VT, Barbosa MD, Detter JC, Patel TD, Achey K, Wakeland EK, Gueorguieva RV, Yang MC, Gossler A, Kingsmore SF
Genomics40(1)170-4(1997 Feb)

Genetic mapping of the choroideremia-like, rab escort protein-2 gene on mouse chromosome 1.
Barbosa MD, Johnson SA, Achey K, Gutierrez MJ, Wakeland EK, Kingsmore SF
Mammalian genome : official journal of the International Mammalian Genome Society6(7)488-9(1995 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Chml gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Chml cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58623	NM_021350.2 Latest version!	Mus musculus choroideremia-like (Chml), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Chml ( NM_021350.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067325.2 Mus musculus choroideremia-like (Chml), mRNA.

Price & Availability↑

CloneID	OMu58623
Clone ID Related Accession (Same CDS sequence)	NM_021350.2
Accession Version	NM_021350.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1866bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Mus musculus(house mouse)
Product	rab proteins geranylgeranyltransferase component A 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC124366.4. On Nov 2, 2007 this sequence version replaced NM_021350.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. COMPLETENESS: complete on the 3' end.

ATGGCGGAGA AGCTTCCCAC AGAGTTTGAT GTGGTAATAA TAGGGACAGG CTTGCCGGAG 
TCCATCCTGG CAGCTGCATG TTCAAGAAGT GGACAGAGAG TTCTGCATGT TGACTCAAGG 
AGTTACTATG GAGGGAATTG GGCGAGTTTC AGCTTTACAG GTTTGCAGTC CTGGCTGAAG 
GACTATCAAC AGAACCATGA CAGCGAGGAA GGCGTGACCG CCACATGGCA AGACCTGATC 
CATGAAACAG AAGAAGCCAT CTCTCTTCGC AAGAAGGATG AAACTATTCA GCACACAGAA 
GTCTTCTGTT ATGCTAGTCA AGATGTGGAG GACAGCGTGC AAGACACCGA GACTCTGCAG 
AGAAGTTCCC CCCTAGAGGC ATCTGCTACT CCGGCTGACT CTCTGGATTC TGCAAGCTTG 
CCCAAAGAAA GGCAGTCAGC TTACTCTACA AGCTATGAAG TGCCTTCTAG ACATACAGAG 
GAAAGTGATA GAGAGCTTTC ACTACCCTCA GCTAATGTGG AGGACTCACT GGAGAAAGAA 
AAGTACTGTG GCGATAAGAC GGATATGCAC ACAGTTTCAG GTGAAGATAA AGGTGAACAC 
AAACTTGTTG TACAAGACAG CATTGAACAA CCAAAGAGAA ATAGGATTAC TTACTCTCAA 
ATGGTTAAGG AGAGCCGGAG ATTTAATATT GACTTGGTAT CAAAGCCGCT GTATTCTCAA 
GGGTCACTGA TTGATCTTCT AATCAAATCA AATGTTAGTC GTTATGCAGA ATTTAAGAAT 
GTCACTAGGA TCCTTGCATT TTGGGAAGGG AAGGTAGAAC AGGTGCCTTG CTCCAGAGCA 
GATGTCTTTA ATAGTAAAGA GCTCAGTATG GTTGAAAAGA GAATGCTAAT GAAGTTTCTT 
ACATTCTGTT TAGACTATGA ACAACATTCT GATGAATACC AAGATTTCAA ACAGTGTTCA 
TTTTCTGACT ACTTAAAAAC TAAAAAACTA ACACCTAATC TCCAGCACTT CATACTACAC 
TCAATTGCAA TGACATCAGA ATCATCTTGC ACTACATTAG ATGGCCTTCA AGCAACAAAA 
ACCTTTCTTC AGTGTCTTGG ACGGTTTGGC AATACTCCCT TTATATTTCC TTTATACGGC 
CACGGAGAAA TTCCCCAGTG TTTCTGCAGG ATGTGTGCAG TTTTTGGTGG AGTCTATTGT 
CTTCGCCATA AAGTACAATG CCTTGTAGTT GACAAAGACT CTGGAAGATG TAAAGGAATC 
ATAGATGCCT TTGGTCAGAG AATAAGTGCC AACTACTTTA TTGTGGAGGA CAGTTATCTT 
CCTAAGGAAA CATGTTCAAA CGTGCAATAT AAGCAGATCT CAAGGGCAGT GCTCATCACA 
GATCAGTCCA TCCTGAAGAC AGATTCGGAC CAGCAGATTT CCATTTTGGT AGTGCCTCCT 
CTGGAGCCAG GAACCACTTC TGTTCGGGTC ATGGAATTAT GTTCGTCAAC CATGACATGC 
ATGAAGGACA GCTATCTGGT CCACCTGACC TGTTCCTCTT CAAAAACAGC CAGAGAAGAC 
TTGGAACCTG TGGTGAAGCA GTTATTCATT CCTGAAGCAG AAGCAGAAGC AGGCAAAGAT 
GAACTCCGAA AACCAAGACT CTTGTGGGCT CTTTATTTTA ATATGAGAGA TTCCTCAGGA 
GTGAGCCGAA GCTCATACTG TGGCTTACCT TCCAATGTGT ACATCTGCTC TGGGCCTGAC 
TGGGGACTGG GGAGTGAGCA TGCAGTCAAG CAGGCGGAAA CACTGTTCCA AGAGATTTTT 
CCCAGTGAAG AGTTCTGCCC TCCTCCACCA AACCCTGAAG ACATCATCTT TGAAGCTGAG 
GGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067325.2
CDS	1..1866
Translation	MAEKLPTEFDVVIIGTGLPESILAAACSRSGQRVLHVDSRSYYGGNWASFSFTGLQSWLKDYQQNHDSEEGVTATWQDLIHETEEAISLRKKDETIQHTEVFCYASQDVEDSVQDTETLQRSSPLEASATPADSLDSASLPKERQSAYSTSYEVPSRHTEESDRELSLPSANVEDSLEKEKYCGDKTDMHTVSGEDKGEHKLVVQDSIEQPKRNRITYSQMVKESRRFNIDLVSKPLYSQGSLIDLLIKSNVSRYAEFKNVTRILAFWEGKVEQVPCSRADVFNSKELSMVEKRMLMKFLTFCLDYEQHSDEYQDFKQCSFSDYLKTKKLTPNLQHFILHSIAMTSESSCTTLDGLQATKTFLQCLGRFGNTPFIFPLYGHGEIPQCFCRMCAVFGGVYCLRHKVQCLVVDKDSGRCKGIIDAFGQRISANYFIVEDSYLPKETCSNVQYKQISRAVLITDQSILKTDSDQQISILVVPPLEPGTTSVRVMELCSSTMTCMKDSYLVHLTCSSSKTAREDLEPVVKQLFIPEAEAEAGKDELRKPRLLWALYFNMRDSSGVSRSSYCGLPSNVYICSGPDWGLGSEHAVKQAETLFQEIFPSEEFCPPPPNPEDIIFEAEG

Target ORF information:

RefSeq Version	NM_021350.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus choroideremia-like (Chml), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021350.2

ORF Insert Sequence:

ATGGCGGAGA AGCTTCCCAC AGAGTTTGAT GTGGTAATAA TAGGGACAGG CTTGCCGGAG 
TCCATCCTGG CAGCTGCATG TTCAAGAAGT GGACAGAGAG TTCTGCATGT TGACTCAAGG 
AGTTACTATG GAGGGAATTG GGCGAGTTTC AGCTTTACAG GTTTGCAGTC CTGGCTGAAG 
GACTATCAAC AGAACCATGA CAGCGAGGAA GGCGTGACCG CCACATGGCA AGACCTGATC 
CATGAAACAG AAGAAGCCAT CTCTCTTCGC AAGAAGGATG AAACTATTCA GCACACAGAA 
GTCTTCTGTT ATGCTAGTCA AGATGTGGAG GACAGCGTGC AAGACACCGA GACTCTGCAG 
AGAAGTTCCC CCCTAGAGGC ATCTGCTACT CCGGCTGACT CTCTGGATTC TGCAAGCTTG 
CCCAAAGAAA GGCAGTCAGC TTACTCTACA AGCTATGAAG TGCCTTCTAG ACATACAGAG 
GAAAGTGATA GAGAGCTTTC ACTACCCTCA GCTAATGTGG AGGACTCACT GGAGAAAGAA 
AAGTACTGTG GCGATAAGAC GGATATGCAC ACAGTTTCAG GTGAAGATAA AGGTGAACAC 
AAACTTGTTG TACAAGACAG CATTGAACAA CCAAAGAGAA ATAGGATTAC TTACTCTCAA 
ATGGTTAAGG AGAGCCGGAG ATTTAATATT GACTTGGTAT CAAAGCCGCT GTATTCTCAA 
GGGTCACTGA TTGATCTTCT AATCAAATCA AATGTTAGTC GTTATGCAGA ATTTAAGAAT 
GTCACTAGGA TCCTTGCATT TTGGGAAGGG AAGGTAGAAC AGGTGCCTTG CTCCAGAGCA 
GATGTCTTTA ATAGTAAAGA GCTCAGTATG GTTGAAAAGA GAATGCTAAT GAAGTTTCTT 
ACATTCTGTT TAGACTATGA ACAACATTCT GATGAATACC AAGATTTCAA ACAGTGTTCA 
TTTTCTGACT ACTTAAAAAC TAAAAAACTA ACACCTAATC TCCAGCACTT CATACTACAC 
TCAATTGCAA TGACATCAGA ATCATCTTGC ACTACATTAG ATGGCCTTCA AGCAACAAAA 
ACCTTTCTTC AGTGTCTTGG ACGGTTTGGC AATACTCCCT TTATATTTCC TTTATACGGC 
CACGGAGAAA TTCCCCAGTG TTTCTGCAGG ATGTGTGCAG TTTTTGGTGG AGTCTATTGT 
CTTCGCCATA AAGTACAATG CCTTGTAGTT GACAAAGACT CTGGAAGATG TAAAGGAATC 
ATAGATGCCT TTGGTCAGAG AATAAGTGCC AACTACTTTA TTGTGGAGGA CAGTTATCTT 
CCTAAGGAAA CATGTTCAAA CGTGCAATAT AAGCAGATCT CAAGGGCAGT GCTCATCACA 
GATCAGTCCA TCCTGAAGAC AGATTCGGAC CAGCAGATTT CCATTTTGGT AGTGCCTCCT 
CTGGAGCCAG GAACCACTTC TGTTCGGGTC ATGGAATTAT GTTCGTCAAC CATGACATGC 
ATGAAGGACA GCTATCTGGT CCACCTGACC TGTTCCTCTT CAAAAACAGC CAGAGAAGAC 
TTGGAACCTG TGGTGAAGCA GTTATTCATT CCTGAAGCAG AAGCAGAAGC AGGCAAAGAT 
GAACTCCGAA AACCAAGACT CTTGTGGGCT CTTTATTTTA ATATGAGAGA TTCCTCAGGA 
GTGAGCCGAA GCTCATACTG TGGCTTACCT TCCAATGTGT ACATCTGCTC TGGGCCTGAC 
TGGGGACTGG GGAGTGAGCA TGCAGTCAAG CAGGCGGAAA CACTGTTCCA AGAGATTTTT 
CCCAGTGAAG AGTTCTGCCC TCCTCCACCA AACCCTGAAG ACATCATCTT TGAAGCTGAG 
GGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Different structural organization of the encephalopsin gene in man and mouse.
Gene295(1)27-32(2002 Jul)
Kasper G,Taudien S,Staub E,Mennerich D,Rieder M,Hinzmann B,Dahl E,Schwidetzky U,Rosenthal A,Rump A

Localization of the Rab escort protein-2 (REP2) and inositol 1,4,5-trisphosphate 3-kinase (ITPKB) genes to mouse chromosome 1 by in situ hybridization and precision of the syntenic regions between mouse and human 1q42-q44.
Genomics43(1)111-3(1997 Jul)
Barrat FJ,Depetris D,Certain S,Mattei MG,de Saint Basile G

Mouse choroideremia gene mutation causes photoreceptor cell degeneration and is not transmitted through the female germline.
Human molecular genetics6(6)851-8(1997 Jun)
van den Hurk JA,Hendriks W,van de Pol DJ,Oerlemans F,Jaissle G,Rüther K,Kohler K,Hartmann J,Zrenner E,van Bokhoven H,Wieringa B,Ropers HH,Cremers FP

Genetic mapping of 20 novel expressed sequence tags from midgestation mouse embryos suggests chromosomal clustering.
Genomics40(1)170-4(1997 Feb)
Tchernev VT,Barbosa MD,Detter JC,Patel TD,Achey K,Wakeland EK,Gueorguieva RV,Yang MC,Gossler A,Kingsmore SF

Genetic mapping of the choroideremia-like, rab escort protein-2 gene on mouse chromosome 1.
Mammalian genome : official journal of the International Mammalian Genome Society6(7)488-9(1995 Jul)
Barbosa MD,Johnson SA,Achey K,Gutierrez MJ,Wakeland EK,Kingsmore SF

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Chml cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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