EIF4E2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EIF4E2
Entrez Gene ID	9470
Full Name	eukaryotic translation initiation factor 4E family member 2
Synonyms	4E-LP,4EHP,EIF4EL3,IF4e,h4EHP
General protein information	Preferred Names eukaryotic translation initiation factor 4E family member 2 Names eukaryotic translation initiation factor 4E type 2 eIF-4E type 2 eIF4E-like cap-binding protein eIF4E-like protein 4E-LP eukaryotic translation initiation factor 4E homologous protein eukaryotic translation initiation factor 4E-like 3 mRNA cap-binding protein type 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q37.1
Disorder MIM:	605895

mRNA and Protein(s)

mRNA	Protein	Name
NM_004846.3	NP_004837.1	eukaryotic translation initiation factor 4E type 2 isoform A
NM_001276337.1	NP_001263266.1	eukaryotic translation initiation factor 4E type 2 isoform D
NM_001282958.1	NP_001269887.1	eukaryotic translation initiation factor 4E type 2 isoform B
NM_001330203.1	NP_001317132.1	eukaryotic translation initiation factor 4E type 2 isoform F
NM_001330201.1	NP_001317130.1	eukaryotic translation initiation factor 4E type 2 isoform E
NM_004846.4	NP_004837.1	eukaryotic translation initiation factor 4E type 2 isoform A
NM_001276336.1	NP_001263265.1	eukaryotic translation initiation factor 4E type 2 isoform C
NM_001330202.1	NP_001317131.1	eukaryotic translation initiation factor 4E type 2 isoform G

Pathways from BioSystems

Homologies

Homo sapiens (human)	EIF4E2	NP_004837.1
Macaca mulatta (Rhesus monkey)	EIF4E2	XP_001114151.2
Mus musculus (house mouse)	Eif4e2	NP_001034259.1
Magnaporthe oryzae (rice blast fungus)	MGG_08170	XP_003715142.1
Neurospora crassa	NCU10582	XP_958765.2
Gallus gallus (chicken)	EIF4E2	XP_422748.2
Canis lupus familiaris (dog)	EIF4E2	NP_001238872.1
Caenorhabditis elegans (roundworm)	ife-4	NP_508210.1
Xenopus tropicalis (tropical clawed frog)	MGC89871	NP_001005099.1
Pan troglodytes (chimpanzee)	EIF4E2	XP_516153.2
Bos taurus (cattle)	EIF4E2	NP_001193345.1
Danio rerio (zebrafish)	eif4e2	NP_001014815.2

Gene Ontology
Bibliography

Related articles in PubMed

Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion.
Kelly NJ, Varga JFA, Specker EJ, Romeo CM, Coomber BL, Uniacke J
Oncogene37(5)651-662(2018 02)

Translational control of ERK signaling through miRNA/4EHP-directed silencing.
Jafarnejad SM, Chapat C, Matta-Camacho E, Gelbart IA, Hesketh GG, Arguello M, Garzia A, Kim SH, Attig J, Shapiro M, Morita M, Khoutorsky A, Alain T, Gkogkas CG, Stern-Ginossar N, Tuschl T, Gingras AC, Duchaine TF, Sonenberg N
eLife7(2018 02)

Major splice variants and multiple polyadenylation site utilization in mRNAs encoding human translation initiation factors eIF4E1 and eIF4E3 regulate the translational regulators?
Mrvová S, Frydrýšková K, Pospíšek M, Vopálenský V, Mašek T
Molecular genetics and genomics : MGG293(1)167-186(2018 Feb)

MicroRNAs recruit eIF4E2 to repress translation of target mRNAs.
Chen S, Gao G
Protein & cell8(10)750-761(2017 Oct)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following EIF4E2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EIF4E2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00439	NM_001282958.1 Latest version!	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu00474	NM_001276336.1 Latest version!	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu04108	NM_001276337.1 Latest version!	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu101628	NM_001330203.1 Latest version!	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu36852	NM_001330201.1 Latest version!	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu62852	NM_001330202.1 Latest version!	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu00384	NM_004846.4 Latest version!	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu00384	NM_004846.3	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EIF4E2 ( NM_001282958.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269887.1 Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu00439
Clone ID Related Accession (Same CDS sequence)	NM_001282958.1
Accession Version	NM_001282958.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E type 2 isoform B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA992544.1, BG913475.1, DA408433.1, AB209519.1, DA592245.1, DA201209.1, AK027239.1 and BG029258.1. On Sep 23, 2013 this sequence version replaced XM_005246973.1. Transcript Variant: This variant (2) contains alternate 3' exon structure and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (B) has a distinct C-terminus and is shorter than isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.259777.1, SRR1803615.258039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGCTGT TGTCCCTGGA CCGGCAGAGC ATCCCCTGCA GTACAACTAC 
ACTTTTTGGT ACTCCAGGAG AACCCCCGGC CGTCCCACGA GCTCACAGAG CTATGAACAG 
AATATCAAAC AGATTGGCAC CTTTGCCTCT GTGGAGCAGT TCTGGAGGTT TTATAGCCAC 
ATGGTACGTC CTGGGGACCT GACAGGCCAC AGTGACTTCC ATCTCTTCAA AGAAGGAATT 
AAACCCATGT GGGAGGATGA TGCAAATAAA AATGGTGGCA AGTGGATTAT TCGGCTGCGG 
AAGGGCTTGG CCTCCCGTTG CTGGGAGAAT CTCATTTTGG CCATGCTGGG GGAACAGTTC 
ATGGTTGGGG AGGAGATCTG TGGGGCTGTG GTGTCTGTCC GCTTTCAGGA AGACATTATT 
TCAATATGGA ATAAGACTGC CAGTGACCAA GCAACCACAG CCCGAATCCG GGACACACTT 
CGGCGAGTGC TTAACCTACC TCCCAACACC ATTATGGAAT ACAAAACTCA CACCGACAGC 
ATCAAGGCCT GGGAGGAGTT TCATGGCCTG GTGAACAGCA GCGGCCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269887.1
CDS	139..849
Translation	MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKAWEEFHGLVNSSGR

Target ORF information:

RefSeq Version	NM_001282958.1
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282958.1

ORF Insert Sequence:

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGCTGT TGTCCCTGGA CCGGCAGAGC ATCCCCTGCA GTACAACTAC 
ACTTTTTGGT ACTCCAGGAG AACCCCCGGC CGTCCCACGA GCTCACAGAG CTATGAACAG 
AATATCAAAC AGATTGGCAC CTTTGCCTCT GTGGAGCAGT TCTGGAGGTT TTATAGCCAC 
ATGGTACGTC CTGGGGACCT GACAGGCCAC AGTGACTTCC ATCTCTTCAA AGAAGGAATT 
AAACCCATGT GGGAGGATGA TGCAAATAAA AATGGTGGCA AGTGGATTAT TCGGCTGCGG 
AAGGGCTTGG CCTCCCGTTG CTGGGAGAAT CTCATTTTGG CCATGCTGGG GGAACAGTTC 
ATGGTTGGGG AGGAGATCTG TGGGGCTGTG GTGTCTGTCC GCTTTCAGGA AGACATTATT 
TCAATATGGA ATAAGACTGC CAGTGACCAA GCAACCACAG CCCGAATCCG GGACACACTT 
CGGCGAGTGC TTAACCTACC TCCCAACACC ATTATGGAAT ACAAAACTCA CACCGACAGC 
ATCAAGGCCT GGGAGGAGTT TCATGGCCTG GTGAACAGCA GCGGCCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E2 ( NM_001276336.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001263265.1 Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu00474
Clone ID Related Accession (Same CDS sequence)	NM_001276336.1
Accession Version	NM_001276336.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 705bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E type 2 isoform C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA992544.1, AB209519.1, DA592245.1, DA201209.1, AK027239.1 and BG029258.1. On Sep 23, 2013 this sequence version replaced XM_005246974.1. Transcript Variant: This variant (3) uses an alternate 3' terminal exon and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (C) has a distinct C-terminus and is shorter than isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.63422.1, SRR1803613.17205.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGCTGT TGTCCCTGGA CCGGCAGAGC ATCCCCTGCA GTACAACTAC 
ACTTTTTGGT ACTCCAGGAG AACCCCCGGC CGTCCCACGA GCTCACAGAG CTATGAACAG 
AATATCAAAC AGATTGGCAC CTTTGCCTCT GTGGAGCAGT TCTGGAGGTT TTATAGCCAC 
ATGGTACGTC CTGGGGACCT GACAGGCCAC AGTGACTTCC ATCTCTTCAA AGAAGGAATT 
AAACCCATGT GGGAGGATGA TGCAAATAAA AATGGTGGCA AGTGGATTAT TCGGCTGCGG 
AAGGGCTTGG CCTCCCGTTG CTGGGAGAAT CTCATTTTGG CCATGCTGGG GGAACAGTTC 
ATGGTTGGGG AGGAGATCTG TGGGGCTGTG GTGTCTGTCC GCTTTCAGGA AGACATTATT 
TCAATATGGA ATAAGACTGC CAGTGACCAA GCAACCACAG CCCGAATCCG GGACACACTT 
CGGCGAGTGC TTAACCTACC TCCCAACACC ATTATGGAAT ACAAAACTCA CACCGACAGC 
ATCAAGGACA ATTCAAGCTT TCGAAATACA AAAATCACAT TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001263265.1
CDS	139..843
Translation	MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKDNSSFRNTKITL

Target ORF information:

RefSeq Version	NM_001276336.1
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001276336.1

ORF Insert Sequence:

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGCTGT TGTCCCTGGA CCGGCAGAGC ATCCCCTGCA GTACAACTAC 
ACTTTTTGGT ACTCCAGGAG AACCCCCGGC CGTCCCACGA GCTCACAGAG CTATGAACAG 
AATATCAAAC AGATTGGCAC CTTTGCCTCT GTGGAGCAGT TCTGGAGGTT TTATAGCCAC 
ATGGTACGTC CTGGGGACCT GACAGGCCAC AGTGACTTCC ATCTCTTCAA AGAAGGAATT 
AAACCCATGT GGGAGGATGA TGCAAATAAA AATGGTGGCA AGTGGATTAT TCGGCTGCGG 
AAGGGCTTGG CCTCCCGTTG CTGGGAGAAT CTCATTTTGG CCATGCTGGG GGAACAGTTC 
ATGGTTGGGG AGGAGATCTG TGGGGCTGTG GTGTCTGTCC GCTTTCAGGA AGACATTATT 
TCAATATGGA ATAAGACTGC CAGTGACCAA GCAACCACAG CCCGAATCCG GGACACACTT 
CGGCGAGTGC TTAACCTACC TCCCAACACC ATTATGGAAT ACAAAACTCA CACCGACAGC 
ATCAAGGACA ATTCAAGCTT TCGAAATACA AAAATCACAT TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E2 ( NM_001276337.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001263266.1 Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu04108
Clone ID Related Accession (Same CDS sequence)	NM_001276337.1
Accession Version	NM_001276337.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E type 2 isoform D
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA992544.1, CD684451.1, AB209519.1, DA592245.1, DA201209.1, AK027239.1 and BG029258.1. Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 5' coding region, and uses an alternate 3' terminal exon and thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (D) has a distinct C-terminus and is shorter than isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.207292.1, SRR1660803.249910.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGTGGA GCAGTTCTGG AGGTTTTATA GCCACATGGT ACGTCCTGGG 
GACCTGACAG GCCACAGTGA CTTCCATCTC TTCAAAGAAG GAATTAAACC CATGTGGGAG 
GATGATGCAA ATAAAAATGG TGGCAAGTGG ATTATTCGGC TGCGGAAGGG CTTGGCCTCC 
CGTTGCTGGG AGAATCTCAT TTTGGCCATG CTGGGGGAAC AGTTCATGGT TGGGGAGGAG 
ATCTGTGGGG CTGTGGTGTC TGTCCGCTTT CAGGAAGACA TTATTTCAAT ATGGAATAAG 
ACTGCCAGTG ACCAAGCAAC CACAGCCCGA ATCCGGGACA CACTTCGGCG AGTGCTTAAC 
CTACCTCCCA ACACCATTAT GGAATACAAA ACTCACACCG ACAGCATCAA GGACAATTCA 
AGCTTTCGAA ATACAAAAAT CACATTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001263266.1
CDS	139..708
Translation	MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKDNSSFRNTKITL

Target ORF information:

RefSeq Version	NM_001276337.1
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001276337.1

ORF Insert Sequence:

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGTGGA GCAGTTCTGG AGGTTTTATA GCCACATGGT ACGTCCTGGG 
GACCTGACAG GCCACAGTGA CTTCCATCTC TTCAAAGAAG GAATTAAACC CATGTGGGAG 
GATGATGCAA ATAAAAATGG TGGCAAGTGG ATTATTCGGC TGCGGAAGGG CTTGGCCTCC 
CGTTGCTGGG AGAATCTCAT TTTGGCCATG CTGGGGGAAC AGTTCATGGT TGGGGAGGAG 
ATCTGTGGGG CTGTGGTGTC TGTCCGCTTT CAGGAAGACA TTATTTCAAT ATGGAATAAG 
ACTGCCAGTG ACCAAGCAAC CACAGCCCGA ATCCGGGACA CACTTCGGCG AGTGCTTAAC 
CTACCTCCCA ACACCATTAT GGAATACAAA ACTCACACCG ACAGCATCAA GGACAATTCA 
AGCTTTCGAA ATACAAAAAT CACATTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E2 ( NM_001330203.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317132.1 Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu101628
Clone ID Related Accession (Same CDS sequence)	NM_001330203.1
Accession Version	NM_001330203.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E type 2 isoform F
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092165.4 and AC073254.6. On Aug 20, 2016 this sequence version replaced XM_017005377.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.175767.1, SRR1660809.124578.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGTGGA GCAGTTCTGG AGGTTTTATA GCCACATGGT ACGTCCTGGG 
GACCTGACAG GCCACAGTGA CTTCCATCTC TTCAAAGAAG GAATTAAACC CATGTGGGAG 
GATGATGCAA ATAAAAATGG TGGCAAGTGG ATTATTCGGC TGCGGAAGGG CTTGGCCTCC 
CGTTGCTGGG AGAATCTCAT TTTGGCCATG CTGGGGGAAC AGTTCATGGT TGGGGAGGAG 
ATCTGTGGGG CTGTGGTGTC TGTCCGCTTT CAGGAAGACA TTATTTCAAT ATGGAATAAG 
ACTGCCAGTG ACCAAGCAAC CACAGCCCGA ATCCGGGACA CACTTCGGCG AGTGCTTAAC 
CTACCTCCCA ACACCATTAT GGAATACAAA ACTCACACCG ACAGCATCAA GGCCTGGGAG 
GAGTTTCATG GCCTGGTGAA CAGCAGCGGC CGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317132.1
CDS	139..714
Translation	MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKAWEEFHGLVNSSGR

Target ORF information:

RefSeq Version	NM_001330203.1
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330203.1

ORF Insert Sequence:

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGTGGA GCAGTTCTGG AGGTTTTATA GCCACATGGT ACGTCCTGGG 
GACCTGACAG GCCACAGTGA CTTCCATCTC TTCAAAGAAG GAATTAAACC CATGTGGGAG 
GATGATGCAA ATAAAAATGG TGGCAAGTGG ATTATTCGGC TGCGGAAGGG CTTGGCCTCC 
CGTTGCTGGG AGAATCTCAT TTTGGCCATG CTGGGGGAAC AGTTCATGGT TGGGGAGGAG 
ATCTGTGGGG CTGTGGTGTC TGTCCGCTTT CAGGAAGACA TTATTTCAAT ATGGAATAAG 
ACTGCCAGTG ACCAAGCAAC CACAGCCCGA ATCCGGGACA CACTTCGGCG AGTGCTTAAC 
CTACCTCCCA ACACCATTAT GGAATACAAA ACTCACACCG ACAGCATCAA GGCCTGGGAG 
GAGTTTCATG GCCTGGTGAA CAGCAGCGGC CGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E2 ( NM_001330201.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317130.1 Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu36852
Clone ID Related Accession (Same CDS sequence)	NM_001330201.1
Accession Version	NM_001330201.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E type 2 isoform E
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092165.4 and AC093383.4. On Aug 20, 2016 this sequence version replaced XM_005246975.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.446862.1, SRR1163658.139541.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGTGGA GCAGTTCTGG AGGTTTTATA GCCACATGGT ACGTCCTGGG 
GACCTGACAG GCCACAGTGA CTTCCATCTC TTCAAAGAAG GAATTAAACC CATGTGGGAG 
GATGATGCAA ATAAAAATGG TGGCAAGTGG ATTATTCGGC TGCGGAAGGG CTTGGCCTCC 
CGTTGCTGGG AGAATCTCAT TTTGGCCATG CTGGGGGAAC AGTTCATGGT TGGGGAGGAG 
ATCTGTGGGG CTGTGGTGTC TGTCCGCTTT CAGGAAGACA TTATTTCAAT ATGGAATAAG 
ACTGCCAGTG ACCAAGCAAC CACAGCCCGA ATCCGGGACA CACTTCGGCG AGTGCTTAAC 
CTACCTCCCA ACACCATTAT GGAATACAAA ACTCACACCG ACAGCATCAA AATGCCAGGC 
AGGCTGGGCC CCCAAAGGCT CCTTTTTCAA AACCTCTGGA AGCCGCGGTT GAATGTGCCA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317130.1
CDS	139..741
Translation	MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGRLGPQRLLFQNLWKPRLNVP

Target ORF information:

RefSeq Version	NM_001330201.1
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330201.1

ORF Insert Sequence:

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGTGGA GCAGTTCTGG AGGTTTTATA GCCACATGGT ACGTCCTGGG 
GACCTGACAG GCCACAGTGA CTTCCATCTC TTCAAAGAAG GAATTAAACC CATGTGGGAG 
GATGATGCAA ATAAAAATGG TGGCAAGTGG ATTATTCGGC TGCGGAAGGG CTTGGCCTCC 
CGTTGCTGGG AGAATCTCAT TTTGGCCATG CTGGGGGAAC AGTTCATGGT TGGGGAGGAG 
ATCTGTGGGG CTGTGGTGTC TGTCCGCTTT CAGGAAGACA TTATTTCAAT ATGGAATAAG 
ACTGCCAGTG ACCAAGCAAC CACAGCCCGA ATCCGGGACA CACTTCGGCG AGTGCTTAAC 
CTACCTCCCA ACACCATTAT GGAATACAAA ACTCACACCG ACAGCATCAA AATGCCAGGC 
AGGCTGGGCC CCCAAAGGCT CCTTTTTCAA AACCTCTGGA AGCCGCGGTT GAATGTGCCA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E2 ( NM_001330202.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317131.1 Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu62852
Clone ID Related Accession (Same CDS sequence)	NM_001330202.1
Accession Version	NM_001330202.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570636800000
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E type 2 isoform G
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092165.4 and AC093383.4. On Aug 20, 2016 this sequence version replaced XM_011512206.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.115825.1, SRR1163657.393299.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTTTGA AAGATGATGA CAGTGGGGAC CATGATCAGA ATGAAGAAAA CAGCACACAG 
AAAGATGGTG AGAAGGAAAA AACGGAACGA GACAAGAATC AGAGCAGTAG CAAGAGAAAG 
GCTGTTGTCC CTGGACCGGC AGAGCATCCC CTGCAGTACA ACTACACTTT TTGGTACTCC 
AGGAGAACCC CCGGCCGTCC CACGAGCTCA CAGAGCTATG AACAGAATAT CAAACAGATT 
GGCACCTTTG CCTCTGTGGA GCAGTTCTGG AGGTTTTATA GCCACATGGT ACGTCCTGGG 
GACCTGACAG GCCACAGTGA CTTCCATCTC TTCAAAGAAG GAATTAAACC CATGTGGGAG 
GATGATGCAA ATAAAAATGG TGGCAAGTGG ATTATTCGGC TGCGGAAGGG CTTGGCCTCC 
CGTTGCTGGG AGAATCTCAT TTTGGCCATG CTGGGGGAAC AGTTCATGGT TGGGGAGGAG 
ATCTGTGGGG CTGTGGTGTC TGTCCGCTTT CAGGAAGACA TTATTTCAAT ATGGAATAAG 
ACTGCCAGTG ACCAAGCAAC CACAGCCCGA ATCCGGGACA CACTTCGGCG AGTGCTTAAC 
CTACCTCCCA ACACCATTAT GGAATACAAA ACTCACACCG ACAGCATCAA AATGCCAGGC 
AGGCTGGGCC CCCAAAGGCT CCTTTTTCAA AACCTCTGGA AGCCGCGGTT GAATGTGCCA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317131.1
CDS	409..1131
Translation	MSLKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGRLGPQRLLFQNLWKPRLNVP

Target ORF information:

RefSeq Version	NM_001330202.1
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330202.1

ORF Insert Sequence:

ATGAGTTTGA AAGATGATGA CAGTGGGGAC CATGATCAGA ATGAAGAAAA CAGCACACAG 
AAAGATGGTG AGAAGGAAAA AACGGAACGA GACAAGAATC AGAGCAGTAG CAAGAGAAAG 
GCTGTTGTCC CTGGACCGGC AGAGCATCCC CTGCAGTACA ACTACACTTT TTGGTACTCC 
AGGAGAACCC CCGGCCGTCC CACGAGCTCA CAGAGCTATG AACAGAATAT CAAACAGATT 
GGCACCTTTG CCTCTGTGGA GCAGTTCTGG AGGTTTTATA GCCACATGGT ACGTCCTGGG 
GACCTGACAG GCCACAGTGA CTTCCATCTC TTCAAAGAAG GAATTAAACC CATGTGGGAG 
GATGATGCAA ATAAAAATGG TGGCAAGTGG ATTATTCGGC TGCGGAAGGG CTTGGCCTCC 
CGTTGCTGGG AGAATCTCAT TTTGGCCATG CTGGGGGAAC AGTTCATGGT TGGGGAGGAG 
ATCTGTGGGG CTGTGGTGTC TGTCCGCTTT CAGGAAGACA TTATTTCAAT ATGGAATAAG 
ACTGCCAGTG ACCAAGCAAC CACAGCCCGA ATCCGGGACA CACTTCGGCG AGTGCTTAAC 
CTACCTCCCA ACACCATTAT GGAATACAAA ACTCACACCG ACAGCATCAA AATGCCAGGC 
AGGCTGGGCC CCCAAAGGCT CCTTTTTCAA AACCTCTGGA AGCCGCGGTT GAATGTGCCA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E2 ( NM_004846.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004837.1 Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00384
Clone ID Related Accession (Same CDS sequence)	NM_004846.3 , NM_004846.4
Accession Version	NM_004846.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1512403200000
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E type 2 isoform A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA992544.1, BC005874.2 and BM018173.1. On Sep 23, 2013 this sequence version replaced NM_004846.2. Transcript Variant: This variant (1) encodes the longest isoform (A). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.412054.1, SRR1163657.177265.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGCTGT TGTCCCTGGA CCGGCAGAGC ATCCCCTGCA GTACAACTAC 
ACTTTTTGGT ACTCCAGGAG AACCCCCGGC CGTCCCACGA GCTCACAGAG CTATGAACAG 
AATATCAAAC AGATTGGCAC CTTTGCCTCT GTGGAGCAGT TCTGGAGGTT TTATAGCCAC 
ATGGTACGTC CTGGGGACCT GACAGGCCAC AGTGACTTCC ATCTCTTCAA AGAAGGAATT 
AAACCCATGT GGGAGGATGA TGCAAATAAA AATGGTGGCA AGTGGATTAT TCGGCTGCGG 
AAGGGCTTGG CCTCCCGTTG CTGGGAGAAT CTCATTTTGG CCATGCTGGG GGAACAGTTC 
ATGGTTGGGG AGGAGATCTG TGGGGCTGTG GTGTCTGTCC GCTTTCAGGA AGACATTATT 
TCAATATGGA ATAAGACTGC CAGTGACCAA GCAACCACAG CCCGAATCCG GGACACACTT 
CGGCGAGTGC TTAACCTACC TCCCAACACC ATTATGGAAT ACAAAACTCA CACCGACAGC 
ATCAAAATGC CAGGCAGGCT GGGCCCCCAA AGGCTCCTTT TTCAAAACCT CTGGAAGCCG 
CGGTTGAATG TGCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004837.1
CDS	139..876
Translation	MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGRLGPQRLLFQNLWKPRLNVP

Target ORF information:

RefSeq Version	NM_004846.3
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004846.3

ORF Insert Sequence:

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGCTGT TGTCCCTGGA CCGGCAGAGC ATCCCCTGCA GTACAACTAC 
ACTTTTTGGT ACTCCAGGAG AACCCCCGGC CGTCCCACGA GCTCACAGAG CTATGAACAG 
AATATCAAAC AGATTGGCAC CTTTGCCTCT GTGGAGCAGT TCTGGAGGTT TTATAGCCAC 
ATGGTACGTC CTGGGGACCT GACAGGCCAC AGTGACTTCC ATCTCTTCAA AGAAGGAATT 
AAACCCATGT GGGAGGATGA TGCAAATAAA AATGGTGGCA AGTGGATTAT TCGGCTGCGG 
AAGGGCTTGG CCTCCCGTTG CTGGGAGAAT CTCATTTTGG CCATGCTGGG GGAACAGTTC 
ATGGTTGGGG AGGAGATCTG TGGGGCTGTG GTGTCTGTCC GCTTTCAGGA AGACATTATT 
TCAATATGGA ATAAGACTGC CAGTGACCAA GCAACCACAG CCCGAATCCG GGACACACTT 
CGGCGAGTGC TTAACCTACC TCCCAACACC ATTATGGAAT ACAAAACTCA CACCGACAGC 
ATCAAAATGC CAGGCAGGCT GGGCCCCCAA AGGCTCCTTT TTCAAAACCT CTGGAAGCCG 
CGGTTGAATG TGCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E2 ( NM_004846.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004837.1 Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00384
Clone ID Related Accession (Same CDS sequence)	NM_004846.3 , NM_004846.4
Accession Version	NM_004846.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E type 2 isoform A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC005874.2. On Nov 22, 2018 this sequence version replaced NM_004846.3. Transcript Variant: This variant (1) encodes the longest isoform (A). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM423333.1, BC005874.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000258416.8/ ENSP00000258416.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGCTGT TGTCCCTGGA CCGGCAGAGC ATCCCCTGCA GTACAACTAC 
ACTTTTTGGT ACTCCAGGAG AACCCCCGGC CGTCCCACGA GCTCACAGAG CTATGAACAG 
AATATCAAAC AGATTGGCAC CTTTGCCTCT GTGGAGCAGT TCTGGAGGTT TTATAGCCAC 
ATGGTACGTC CTGGGGACCT GACAGGCCAC AGTGACTTCC ATCTCTTCAA AGAAGGAATT 
AAACCCATGT GGGAGGATGA TGCAAATAAA AATGGTGGCA AGTGGATTAT TCGGCTGCGG 
AAGGGCTTGG CCTCCCGTTG CTGGGAGAAT CTCATTTTGG CCATGCTGGG GGAACAGTTC 
ATGGTTGGGG AGGAGATCTG TGGGGCTGTG GTGTCTGTCC GCTTTCAGGA AGACATTATT 
TCAATATGGA ATAAGACTGC CAGTGACCAA GCAACCACAG CCCGAATCCG GGACACACTT 
CGGCGAGTGC TTAACCTACC TCCCAACACC ATTATGGAAT ACAAAACTCA CACCGACAGC 
ATCAAAATGC CAGGCAGGCT GGGCCCCCAA AGGCTCCTTT TTCAAAACCT CTGGAAGCCG 
CGGTTGAATG TGCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004837.1
CDS	37..774
Translation	MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGRLGPQRLLFQNLWKPRLNVP

Target ORF information:

RefSeq Version	NM_004846.4
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E family member 2 (EIF4E2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004846.4

ORF Insert Sequence:

ATGAACAACA AGTTCGACGC TTTGAAAGAT GATGACAGTG GGGACCATGA TCAGAATGAA 
GAAAACAGCA CACAGAAAGA TGGTGAGAAG GAAAAAACGG AACGAGACAA GAATCAGAGC 
AGTAGCAAGA GAAAGGCTGT TGTCCCTGGA CCGGCAGAGC ATCCCCTGCA GTACAACTAC 
ACTTTTTGGT ACTCCAGGAG AACCCCCGGC CGTCCCACGA GCTCACAGAG CTATGAACAG 
AATATCAAAC AGATTGGCAC CTTTGCCTCT GTGGAGCAGT TCTGGAGGTT TTATAGCCAC 
ATGGTACGTC CTGGGGACCT GACAGGCCAC AGTGACTTCC ATCTCTTCAA AGAAGGAATT 
AAACCCATGT GGGAGGATGA TGCAAATAAA AATGGTGGCA AGTGGATTAT TCGGCTGCGG 
AAGGGCTTGG CCTCCCGTTG CTGGGAGAAT CTCATTTTGG CCATGCTGGG GGAACAGTTC 
ATGGTTGGGG AGGAGATCTG TGGGGCTGTG GTGTCTGTCC GCTTTCAGGA AGACATTATT 
TCAATATGGA ATAAGACTGC CAGTGACCAA GCAACCACAG CCCGAATCCG GGACACACTT 
CGGCGAGTGC TTAACCTACC TCCCAACACC ATTATGGAAT ACAAAACTCA CACCGACAGC 
ATCAAAATGC CAGGCAGGCT GGGCCCCCAA AGGCTCCTTT TTCAAAACCT CTGGAAGCCG 
CGGTTGAATG TGCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion.
Oncogene37(5)651-662(2018 02)
Kelly NJ,Varga JFA,Specker EJ,Romeo CM,Coomber BL,Uniacke J

Translational control of ERK signaling through miRNA/4EHP-directed silencing.
eLife7(2018 02)
Jafarnejad SM,Chapat C,Matta-Camacho E,Gelbart IA,Hesketh GG,Arguello M,Garzia A,Kim SH,Attig J,Shapiro M,Morita M,Khoutorsky A,Alain T,Gkogkas CG,Stern-Ginossar N,Tuschl T,Gingras AC,Duchaine TF,Sonenberg N

Major splice variants and multiple polyadenylation site utilization in mRNAs encoding human translation initiation factors eIF4E1 and eIF4E3 regulate the translational regulators?
Molecular genetics and genomics : MGG293(1)167-186(2018 Feb)
Mrvová S,Frydrýšková K,Pospíšek M,Vopálenský V,Mašek T

MicroRNAs recruit eIF4E2 to repress translation of target mRNAs.
Protein & cell8(10)750-761(2017 Oct)
Chen S,Gao G

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

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EIF4E2 cDNA ORF clone, Homo sapiens(human)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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