| Gene Symbol | TAF1C |
| Entrez Gene ID | 9013 |
| Full Name | TATA-box binding protein associated factor, RNA polymerase I subunit C |
| Synonyms | MGC:39976,SL1,TAFI110,TAFI95 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]. |
| Disorder MIM: |
User Manual