WDR83 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	WDR83
Entrez Gene ID	84292
Full Name	WD repeat domain 83
Synonyms	MORG1
General protein information	Preferred Names WD repeat domain 83 Names WD repeat domain-containing protein 83 MAPK organizer 1 mitogen-activated protein kinase organizer 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.13
Summary	This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
Disorder MIM:	616850

mRNA and Protein(s)

mRNA	Protein	Name
NM_032332.3	NP_115708.1	WD repeat domain-containing protein 83
NM_032332.4	NP_115708.1	WD repeat domain-containing protein 83
NM_001099737.2	NP_001093207.1	WD repeat domain-containing protein 83
NM_001099737.3	NP_001093207.1	WD repeat domain-containing protein 83

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008129	XP_317330.3
Rattus norvegicus (Norway rat)	Wdr83	NP_001041312.1
Caenorhabditis elegans (roundworm)	F33G12.2	NP_494926.1
Oryza sativa (rice)	Os02g0543400	NP_001047075.1
Canis lupus familiaris (dog)	WDR83	XP_542047.1
Bos taurus (cattle)	WDR83	NP_001073118.1
Mus musculus (house mouse)	Wdr83	NP_080675.2
Homo sapiens (human)	WDR83	NP_115708.1
Pan troglodytes (chimpanzee)	WDR83	XP_003953427.1
Danio rerio (zebrafish)	wdr83	NP_001002429.1
Drosophila melanogaster (fruit fly)	CG4935	NP_609782.2
Macaca mulatta (Rhesus monkey)	WDR83	XP_001108218.1
Arabidopsis thaliana (thale cress)	AT5G64730	NP_568993.1
Xenopus tropicalis (tropical clawed frog)	wdr83	NP_001011071.1

Gene Ontology
Bibliography

Related articles in PubMed

The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells.
Hayase J, Kamakura S, Iwakiri Y, Yamaguchi Y, Izaki T, Ito T, Sumimoto H
The Journal of cell biology200(5)635-50(2013 Mar)

Bidirectional regulation between WDR83 and its natural antisense transcript DHPS in gastric cancer.
Su WY, Li JT, Cui Y, Hong J, Du W, Wang YC, Lin YW, Xiong H, Wang JL, Kong X, Gao QY, Wei LP, Fang JY
Cell research22(9)1374-89(2012 Sep)

Dynamic protein-protein interaction wiring of the human spliceosome.
Hegele A, Kamburov A, Grossmann A, Sourlis C, Wowro S, Weimann M, Will CL, Pena V, Lührmann R, Stelzl U
Molecular cell45(4)567-80(2012 Feb)

Reduced Morg1 expression in ischemic human brain.
Haase D, Keiner S, Mawrin C, Wolf G
Neuroscience letters455(1)46-50(2009 May)

Comparative proteomic analysis of human leukemic cells with and without inducible expression of leukemogenic AML1-ETO protein.
Zhang L, Wang LS, Xu Y, Xia L, Chen WL, Zheng Y, Chen GQ
The Chinese journal of physiology49(4)182-91(2006 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following WDR83 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WDR83 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04969	NM_001099737.3 Latest version!	Homo sapiens WD repeat domain 83 (WDR83), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OHu04969	NM_032332.4 Latest version!	Homo sapiens WD repeat domain 83 (WDR83), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
View Old Accession Versions >>
OHu04969	NM_032332.3	Homo sapiens WD repeat domain 83 (WDR83), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OHu04969	NM_001099737.2	Homo sapiens WD repeat domain 83 (WDR83), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

WDR83 ( NM_032332.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_115708.1 Homo sapiens WD repeat domain 83 (WDR83), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04969
Clone ID Related Accession (Same CDS sequence)	NM_032332.3 , NM_032332.4 , NM_001099737.2 , NM_001099737.3
Accession Version	NM_032332.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529683200000
Organism	Homo sapiens(human)
Product	WD repeat domain-containing protein 83
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB143206.1 and BC005870.2. On Jul 25, 2007 this sequence version replaced NM_032332.2. Transcript Variant: This variant (2) represents use of an alternate promoter and 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.557540.1, SRR1163658.209885.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTTCC CTGAGCCAAA GCCGCGGCCT CCAGAGCTGC CGCAGAAACG GTTGAAGACG 
CTGGACTGCG GGCAGGGGGC AGTGCGAGCC GTACGATTTA ATGTGGATGG CAATTACTGC 
CTGACGTGCG GCAGTGACAA GACGCTGAAG CTGTGGAACC CGCTTCGGGG GACGCTGCTG 
CGGACGTACA GCGGCCACGG CTACGAGGTG CTGGATGCGG CCGGCTCCTT TGACAACAGT 
AGTCTCTGCT CCGGCGGCGG GGACAAGGCG GTGGTTCTGT GGGATGTGGC ATCAGGGCAG 
GTCGTGCGCA AATTCCGGGG CCACGCAGGG AAGGTGAACA CGGTGCAGTT TAATGAAGAG 
GCCACAGTTA TCCTGTCCGG CTCTATTGAT TCCAGTATCC GCTGTTGGGA TTGCCGCTCA 
CGGAGGCCTG AGCCAGTGCA GACGCTGGAT GAGGCCAGAG ATGGCGTGTC CAGTGTGAAG 
GTGTCAGACC ACGAGATCCT GGCAGGCTCC GTGGATGGCC GCGTGAGACG CTATGACCTA 
AGGATGGGGC AGCTCTTCTC AGACTACGTG GGCAGCCCCA TCACCTGCAC CTGCTTCAGC 
CGGGATGGGC AGTGCACCCT GGTGTCCAGC CTGGACTCCA CATTGCGGCT CCTGGACAAA 
GACACAGGGG AGCTGCTGGG CGAGTACAAG GGCCATAAGA ACCAGGAATA CAAGCTGGAC 
TGCTGCCTGA GCGAGCGTGA CACACATGTG GTCAGCTGTT CTGAGGACGG GAAGGTGTTC 
TTCTGGGACC TGGTGGAGGG TGCGCTGGCT CTGGCCCTGC CTGTGGGTTC CGGTGTGGTG 
CAGTCGCTGG CCTACCACCC AACAGAGCCC TGCCTGCTGA CCGCCATGGG AGGCAGCGTC 
CAGTGCTGGC GAGAGGAGGC CTATGAGGCA GAGGATGGAG CAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115708.1
CDS	89..1036
Translation	MAFPEPKPRPPELPQKRLKTLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVGSGVVQSLAYHPTEPCLLTAMGGSVQCWREEAYEAEDGAG

Target ORF information:

RefSeq Version	NM_032332.3
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 83 (WDR83), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032332.3

ORF Insert Sequence:

ATGGCTTTCC CTGAGCCAAA GCCGCGGCCT CCAGAGCTGC CGCAGAAACG GTTGAAGACG 
CTGGACTGCG GGCAGGGGGC AGTGCGAGCC GTACGATTTA ATGTGGATGG CAATTACTGC 
CTGACGTGCG GCAGTGACAA GACGCTGAAG CTGTGGAACC CGCTTCGGGG GACGCTGCTG 
CGGACGTACA GCGGCCACGG CTACGAGGTG CTGGATGCGG CCGGCTCCTT TGACAACAGT 
AGTCTCTGCT CCGGCGGCGG GGACAAGGCG GTGGTTCTGT GGGATGTGGC ATCAGGGCAG 
GTCGTGCGCA AATTCCGGGG CCACGCAGGG AAGGTGAACA CGGTGCAGTT TAATGAAGAG 
GCCACAGTTA TCCTGTCCGG CTCTATTGAT TCCAGTATCC GCTGTTGGGA TTGCCGCTCA 
CGGAGGCCTG AGCCAGTGCA GACGCTGGAT GAGGCCAGAG ATGGCGTGTC CAGTGTGAAG 
GTGTCAGACC ACGAGATCCT GGCAGGCTCC GTGGATGGCC GCGTGAGACG CTATGACCTA 
AGGATGGGGC AGCTCTTCTC AGACTACGTG GGCAGCCCCA TCACCTGCAC CTGCTTCAGC 
CGGGATGGGC AGTGCACCCT GGTGTCCAGC CTGGACTCCA CATTGCGGCT CCTGGACAAA 
GACACAGGGG AGCTGCTGGG CGAGTACAAG GGCCATAAGA ACCAGGAATA CAAGCTGGAC 
TGCTGCCTGA GCGAGCGTGA CACACATGTG GTCAGCTGTT CTGAGGACGG GAAGGTGTTC 
TTCTGGGACC TGGTGGAGGG TGCGCTGGCT CTGGCCCTGC CTGTGGGTTC CGGTGTGGTG 
CAGTCGCTGG CCTACCACCC AACAGAGCCC TGCCTGCTGA CCGCCATGGG AGGCAGCGTC 
CAGTGCTGGC GAGAGGAGGC CTATGAGGCA GAGGATGGAG CAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDR83 ( NM_032332.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_115708.1 Homo sapiens WD repeat domain 83 (WDR83), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04969
Clone ID Related Accession (Same CDS sequence)	NM_032332.3 , NM_032332.4 , NM_001099737.2 , NM_001099737.3
Accession Version	NM_032332.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569513600000
Organism	Homo sapiens(human)
Product	WD repeat domain-containing protein 83
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB143206.1 and BC005870.2. On May 31, 2019 this sequence version replaced NM_032332.3. Transcript Variant: This variant (2) represents use of an alternate promoter and 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC005870.2, AK223195.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTTCC CTGAGCCAAA GCCGCGGCCT CCAGAGCTGC CGCAGAAACG GTTGAAGACG 
CTGGACTGCG GGCAGGGGGC AGTGCGAGCC GTACGATTTA ATGTGGATGG CAATTACTGC 
CTGACGTGCG GCAGTGACAA GACGCTGAAG CTGTGGAACC CGCTTCGGGG GACGCTGCTG 
CGGACGTACA GCGGCCACGG CTACGAGGTG CTGGATGCGG CCGGCTCCTT TGACAACAGT 
AGTCTCTGCT CCGGCGGCGG GGACAAGGCG GTGGTTCTGT GGGATGTGGC ATCAGGGCAG 
GTCGTGCGCA AATTCCGGGG CCACGCAGGG AAGGTGAACA CGGTGCAGTT TAATGAAGAG 
GCCACAGTTA TCCTGTCCGG CTCTATTGAT TCCAGTATCC GCTGTTGGGA TTGCCGCTCA 
CGGAGGCCTG AGCCAGTGCA GACGCTGGAT GAGGCCAGAG ATGGCGTGTC CAGTGTGAAG 
GTGTCAGACC ACGAGATCCT GGCAGGCTCC GTGGATGGCC GCGTGAGACG CTATGACCTA 
AGGATGGGGC AGCTCTTCTC AGACTACGTG GGCAGCCCCA TCACCTGCAC CTGCTTCAGC 
CGGGATGGGC AGTGCACCCT GGTGTCCAGC CTGGACTCCA CATTGCGGCT CCTGGACAAA 
GACACAGGGG AGCTGCTGGG CGAGTACAAG GGCCATAAGA ACCAGGAATA CAAGCTGGAC 
TGCTGCCTGA GCGAGCGTGA CACACATGTG GTCAGCTGTT CTGAGGACGG GAAGGTGTTC 
TTCTGGGACC TGGTGGAGGG TGCGCTGGCT CTGGCCCTGC CTGTGGGTTC CGGTGTGGTG 
CAGTCGCTGG CCTACCACCC AACAGAGCCC TGCCTGCTGA CCGCCATGGG AGGCAGCGTC 
CAGTGCTGGC GAGAGGAGGC CTATGAGGCA GAGGATGGAG CAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115708.1
CDS	39..986
Translation	MAFPEPKPRPPELPQKRLKTLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVGSGVVQSLAYHPTEPCLLTAMGGSVQCWREEAYEAEDGAG

Target ORF information:

RefSeq Version	NM_032332.4
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 83 (WDR83), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032332.4

ORF Insert Sequence:

ATGGCTTTCC CTGAGCCAAA GCCGCGGCCT CCAGAGCTGC CGCAGAAACG GTTGAAGACG 
CTGGACTGCG GGCAGGGGGC AGTGCGAGCC GTACGATTTA ATGTGGATGG CAATTACTGC 
CTGACGTGCG GCAGTGACAA GACGCTGAAG CTGTGGAACC CGCTTCGGGG GACGCTGCTG 
CGGACGTACA GCGGCCACGG CTACGAGGTG CTGGATGCGG CCGGCTCCTT TGACAACAGT 
AGTCTCTGCT CCGGCGGCGG GGACAAGGCG GTGGTTCTGT GGGATGTGGC ATCAGGGCAG 
GTCGTGCGCA AATTCCGGGG CCACGCAGGG AAGGTGAACA CGGTGCAGTT TAATGAAGAG 
GCCACAGTTA TCCTGTCCGG CTCTATTGAT TCCAGTATCC GCTGTTGGGA TTGCCGCTCA 
CGGAGGCCTG AGCCAGTGCA GACGCTGGAT GAGGCCAGAG ATGGCGTGTC CAGTGTGAAG 
GTGTCAGACC ACGAGATCCT GGCAGGCTCC GTGGATGGCC GCGTGAGACG CTATGACCTA 
AGGATGGGGC AGCTCTTCTC AGACTACGTG GGCAGCCCCA TCACCTGCAC CTGCTTCAGC 
CGGGATGGGC AGTGCACCCT GGTGTCCAGC CTGGACTCCA CATTGCGGCT CCTGGACAAA 
GACACAGGGG AGCTGCTGGG CGAGTACAAG GGCCATAAGA ACCAGGAATA CAAGCTGGAC 
TGCTGCCTGA GCGAGCGTGA CACACATGTG GTCAGCTGTT CTGAGGACGG GAAGGTGTTC 
TTCTGGGACC TGGTGGAGGG TGCGCTGGCT CTGGCCCTGC CTGTGGGTTC CGGTGTGGTG 
CAGTCGCTGG CCTACCACCC AACAGAGCCC TGCCTGCTGA CCGCCATGGG AGGCAGCGTC 
CAGTGCTGGC GAGAGGAGGC CTATGAGGCA GAGGATGGAG CAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDR83 ( NM_001099737.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093207.1 Homo sapiens WD repeat domain 83 (WDR83), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04969
Clone ID Related Accession (Same CDS sequence)	NM_032332.3 , NM_032332.4 , NM_001099737.2 , NM_001099737.3
Accession Version	NM_001099737.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	WD repeat domain-containing protein 83
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z46189.1, AK314164.1 and BC005870.2. This sequence is a reference standard in the RefSeqGene project. On Oct 8, 2009 this sequence version replaced NM_001099737.1. Transcript Variant: This variant (1) represents the longest transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.188019.1, SRR1163655.387263.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTTCC CTGAGCCAAA GCCGCGGCCT CCAGAGCTGC CGCAGAAACG GTTGAAGACG 
CTGGACTGCG GGCAGGGGGC AGTGCGAGCC GTACGATTTA ATGTGGATGG CAATTACTGC 
CTGACGTGCG GCAGTGACAA GACGCTGAAG CTGTGGAACC CGCTTCGGGG GACGCTGCTG 
CGGACGTACA GCGGCCACGG CTACGAGGTG CTGGATGCGG CCGGCTCCTT TGACAACAGT 
AGTCTCTGCT CCGGCGGCGG GGACAAGGCG GTGGTTCTGT GGGATGTGGC ATCAGGGCAG 
GTCGTGCGCA AATTCCGGGG CCACGCAGGG AAGGTGAACA CGGTGCAGTT TAATGAAGAG 
GCCACAGTTA TCCTGTCCGG CTCTATTGAT TCCAGTATCC GCTGTTGGGA TTGCCGCTCA 
CGGAGGCCTG AGCCAGTGCA GACGCTGGAT GAGGCCAGAG ATGGCGTGTC CAGTGTGAAG 
GTGTCAGACC ACGAGATCCT GGCAGGCTCC GTGGATGGCC GCGTGAGACG CTATGACCTA 
AGGATGGGGC AGCTCTTCTC AGACTACGTG GGCAGCCCCA TCACCTGCAC CTGCTTCAGC 
CGGGATGGGC AGTGCACCCT GGTGTCCAGC CTGGACTCCA CATTGCGGCT CCTGGACAAA 
GACACAGGGG AGCTGCTGGG CGAGTACAAG GGCCATAAGA ACCAGGAATA CAAGCTGGAC 
TGCTGCCTGA GCGAGCGTGA CACACATGTG GTCAGCTGTT CTGAGGACGG GAAGGTGTTC 
TTCTGGGACC TGGTGGAGGG TGCGCTGGCT CTGGCCCTGC CTGTGGGTTC CGGTGTGGTG 
CAGTCGCTGG CCTACCACCC AACAGAGCCC TGCCTGCTGA CCGCCATGGG AGGCAGCGTC 
CAGTGCTGGC GAGAGGAGGC CTATGAGGCA GAGGATGGAG CAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093207.1
CDS	346..1293
Translation	MAFPEPKPRPPELPQKRLKTLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVGSGVVQSLAYHPTEPCLLTAMGGSVQCWREEAYEAEDGAG

Target ORF information:

RefSeq Version	NM_001099737.2
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 83 (WDR83), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001099737.2

ORF Insert Sequence:

ATGGCTTTCC CTGAGCCAAA GCCGCGGCCT CCAGAGCTGC CGCAGAAACG GTTGAAGACG 
CTGGACTGCG GGCAGGGGGC AGTGCGAGCC GTACGATTTA ATGTGGATGG CAATTACTGC 
CTGACGTGCG GCAGTGACAA GACGCTGAAG CTGTGGAACC CGCTTCGGGG GACGCTGCTG 
CGGACGTACA GCGGCCACGG CTACGAGGTG CTGGATGCGG CCGGCTCCTT TGACAACAGT 
AGTCTCTGCT CCGGCGGCGG GGACAAGGCG GTGGTTCTGT GGGATGTGGC ATCAGGGCAG 
GTCGTGCGCA AATTCCGGGG CCACGCAGGG AAGGTGAACA CGGTGCAGTT TAATGAAGAG 
GCCACAGTTA TCCTGTCCGG CTCTATTGAT TCCAGTATCC GCTGTTGGGA TTGCCGCTCA 
CGGAGGCCTG AGCCAGTGCA GACGCTGGAT GAGGCCAGAG ATGGCGTGTC CAGTGTGAAG 
GTGTCAGACC ACGAGATCCT GGCAGGCTCC GTGGATGGCC GCGTGAGACG CTATGACCTA 
AGGATGGGGC AGCTCTTCTC AGACTACGTG GGCAGCCCCA TCACCTGCAC CTGCTTCAGC 
CGGGATGGGC AGTGCACCCT GGTGTCCAGC CTGGACTCCA CATTGCGGCT CCTGGACAAA 
GACACAGGGG AGCTGCTGGG CGAGTACAAG GGCCATAAGA ACCAGGAATA CAAGCTGGAC 
TGCTGCCTGA GCGAGCGTGA CACACATGTG GTCAGCTGTT CTGAGGACGG GAAGGTGTTC 
TTCTGGGACC TGGTGGAGGG TGCGCTGGCT CTGGCCCTGC CTGTGGGTTC CGGTGTGGTG 
CAGTCGCTGG CCTACCACCC AACAGAGCCC TGCCTGCTGA CCGCCATGGG AGGCAGCGTC 
CAGTGCTGGC GAGAGGAGGC CTATGAGGCA GAGGATGGAG CAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDR83 ( NM_001099737.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093207.1 Homo sapiens WD repeat domain 83 (WDR83), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04969
Clone ID Related Accession (Same CDS sequence)	NM_032332.3 , NM_032332.4 , NM_001099737.2 , NM_001099737.3
Accession Version	NM_001099737.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571760000000
Organism	Homo sapiens(human)
Product	WD repeat domain-containing protein 83
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z46189.1, AK314164.1 and BC005870.2. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001099737.2. Transcript Variant: This variant (1) represents the longest transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.680912.1, SRR3476690.661101.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000418543.8/ ENSP00000402653.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTTTCC CTGAGCCAAA GCCGCGGCCT CCAGAGCTGC CGCAGAAACG GTTGAAGACG 
CTGGACTGCG GGCAGGGGGC AGTGCGAGCC GTACGATTTA ATGTGGATGG CAATTACTGC 
CTGACGTGCG GCAGTGACAA GACGCTGAAG CTGTGGAACC CGCTTCGGGG GACGCTGCTG 
CGGACGTACA GCGGCCACGG CTACGAGGTG CTGGATGCGG CCGGCTCCTT TGACAACAGT 
AGTCTCTGCT CCGGCGGCGG GGACAAGGCG GTGGTTCTGT GGGATGTGGC ATCAGGGCAG 
GTCGTGCGCA AATTCCGGGG CCACGCAGGG AAGGTGAACA CGGTGCAGTT TAATGAAGAG 
GCCACAGTTA TCCTGTCCGG CTCTATTGAT TCCAGTATCC GCTGTTGGGA TTGCCGCTCA 
CGGAGGCCTG AGCCAGTGCA GACGCTGGAT GAGGCCAGAG ATGGCGTGTC CAGTGTGAAG 
GTGTCAGACC ACGAGATCCT GGCAGGCTCC GTGGATGGCC GCGTGAGACG CTATGACCTA 
AGGATGGGGC AGCTCTTCTC AGACTACGTG GGCAGCCCCA TCACCTGCAC CTGCTTCAGC 
CGGGATGGGC AGTGCACCCT GGTGTCCAGC CTGGACTCCA CATTGCGGCT CCTGGACAAA 
GACACAGGGG AGCTGCTGGG CGAGTACAAG GGCCATAAGA ACCAGGAATA CAAGCTGGAC 
TGCTGCCTGA GCGAGCGTGA CACACATGTG GTCAGCTGTT CTGAGGACGG GAAGGTGTTC 
TTCTGGGACC TGGTGGAGGG TGCGCTGGCT CTGGCCCTGC CTGTGGGTTC CGGTGTGGTG 
CAGTCGCTGG CCTACCACCC AACAGAGCCC TGCCTGCTGA CCGCCATGGG AGGCAGCGTC 
CAGTGCTGGC GAGAGGAGGC CTATGAGGCA GAGGATGGAG CAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093207.1
CDS	343..1290
Translation	MAFPEPKPRPPELPQKRLKTLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVGSGVVQSLAYHPTEPCLLTAMGGSVQCWREEAYEAEDGAG

Target ORF information:

RefSeq Version	NM_001099737.3
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 83 (WDR83), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001099737.3

ORF Insert Sequence:

ATGGCTTTCC CTGAGCCAAA GCCGCGGCCT CCAGAGCTGC CGCAGAAACG GTTGAAGACG 
CTGGACTGCG GGCAGGGGGC AGTGCGAGCC GTACGATTTA ATGTGGATGG CAATTACTGC 
CTGACGTGCG GCAGTGACAA GACGCTGAAG CTGTGGAACC CGCTTCGGGG GACGCTGCTG 
CGGACGTACA GCGGCCACGG CTACGAGGTG CTGGATGCGG CCGGCTCCTT TGACAACAGT 
AGTCTCTGCT CCGGCGGCGG GGACAAGGCG GTGGTTCTGT GGGATGTGGC ATCAGGGCAG 
GTCGTGCGCA AATTCCGGGG CCACGCAGGG AAGGTGAACA CGGTGCAGTT TAATGAAGAG 
GCCACAGTTA TCCTGTCCGG CTCTATTGAT TCCAGTATCC GCTGTTGGGA TTGCCGCTCA 
CGGAGGCCTG AGCCAGTGCA GACGCTGGAT GAGGCCAGAG ATGGCGTGTC CAGTGTGAAG 
GTGTCAGACC ACGAGATCCT GGCAGGCTCC GTGGATGGCC GCGTGAGACG CTATGACCTA 
AGGATGGGGC AGCTCTTCTC AGACTACGTG GGCAGCCCCA TCACCTGCAC CTGCTTCAGC 
CGGGATGGGC AGTGCACCCT GGTGTCCAGC CTGGACTCCA CATTGCGGCT CCTGGACAAA 
GACACAGGGG AGCTGCTGGG CGAGTACAAG GGCCATAAGA ACCAGGAATA CAAGCTGGAC 
TGCTGCCTGA GCGAGCGTGA CACACATGTG GTCAGCTGTT CTGAGGACGG GAAGGTGTTC 
TTCTGGGACC TGGTGGAGGG TGCGCTGGCT CTGGCCCTGC CTGTGGGTTC CGGTGTGGTG 
CAGTCGCTGG CCTACCACCC AACAGAGCCC TGCCTGCTGA CCGCCATGGG AGGCAGCGTC 
CAGTGCTGGC GAGAGGAGGC CTATGAGGCA GAGGATGGAG CAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells.
The Journal of cell biology200(5)635-50(2013 Mar)
Hayase J,Kamakura S,Iwakiri Y,Yamaguchi Y,Izaki T,Ito T,Sumimoto H

Bidirectional regulation between WDR83 and its natural antisense transcript DHPS in gastric cancer.
Cell research22(9)1374-89(2012 Sep)
Su WY,Li JT,Cui Y,Hong J,Du W,Wang YC,Lin YW,Xiong H,Wang JL,Kong X,Gao QY,Wei LP,Fang JY

Dynamic protein-protein interaction wiring of the human spliceosome.
Molecular cell45(4)567-80(2012 Feb)
Hegele A,Kamburov A,Grossmann A,Sourlis C,Wowro S,Weimann M,Will CL,Pena V,Lührmann R,Stelzl U

Reduced Morg1 expression in ischemic human brain.
Neuroscience letters455(1)46-50(2009 May)
Haase D,Keiner S,Mawrin C,Wolf G

Comparative proteomic analysis of human leukemic cells with and without inducible expression of leukemogenic AML1-ETO protein.
The Chinese journal of physiology49(4)182-91(2006 Aug)
Zhang L,Wang LS,Xu Y,Xia L,Chen WL,Zheng Y,Chen GQ

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WDR83 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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