ALDH8A1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ALDH8A1
Entrez Gene ID	64577
Full Name	aldehyde dehydrogenase 8 family member A1
Synonyms	ALDH12,DJ352A20.2
General protein information	Preferred Names aldehyde dehydrogenase 8 family member A1 Names aldehyde dehydrogenase family 8 member A1 aldehyde dehydrogenase 12 aldehyde dehydrogenase family protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q23.3
Summary	This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. [provided by RefSeq, Jul 2010].
Disorder MIM:	606467

mRNA and Protein(s)

mRNA	Protein	Name
NM_170771.3	NP_739577.1	2-aminomuconic semialdehyde dehydrogenase isoform 2
NM_022568.4	NP_072090.1	2-aminomuconic semialdehyde dehydrogenase isoform 1
NM_001193480.2	NP_001180409.1	2-aminomuconic semialdehyde dehydrogenase isoform 3
NM_170771.2	NP_739577.1	2-aminomuconic semialdehyde dehydrogenase isoform 2
NM_022568.3	NP_072090.1	aldehyde dehydrogenase family 8 member A1 isoform 1
NM_001193480.1	NP_001180409.1	2-aminomuconic semialdehyde dehydrogenase isoform 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	ALDH8A1	NP_072090.1
Pan troglodytes (chimpanzee)	ALDH8A1	XP_001170111.2
Canis lupus familiaris (dog)	ALDH8A1	XP_533415.2
Bos taurus (cattle)	ALDH8A1	NP_001069094.1
Gallus gallus (chicken)	ALDH8A1	XP_419732.1
Caenorhabditis elegans (roundworm)	alh-10	NP_509203.1
Xenopus tropicalis (tropical clawed frog)	aldh8a1	XP_002935852.1
Danio rerio (zebrafish)	aldh8a1	NP_001004540.1
Macaca mulatta (Rhesus monkey)	LOC712386	XP_001101362.1
Mus musculus (house mouse)	Aldh8a1	NP_848828.1
Rattus norvegicus (Norway rat)	Aldh8a1	NP_001178017.1

Gene Ontology
Bibliography

Related articles in PubMed

Reassignment of the human aldehyde dehydrogenase ALDH8A1 (ALDH12) to the kynurenine pathway in tryptophan catabolism.
Davis I, Yang Y, Wherritt D, Liu A
The Journal of biological chemistry293(25)9594-9603(2018 06)

Genetics of coronary artery calcification among African Americans, a meta-analysis.
Wojczynski MK, Li M, Bielak LF, Kerr KF, Reiner AP, Wong ND, Yanek LR, Qu L, White CC, Lange LA, Ferguson JF, He J, Young T, Mosley TH, Smith JA, Kral BG, Guo X, Wong Q, Ganesh SK, Heckbert SR, Griswold ME, O'Leary DH, Budoff M, Carr JJ, Taylor HA Jr, Bluemke DA, Demissie S, Hwang SJ, Paltoo DN, Polak JF, Psaty BM, Becker DM, Province MA, Post WS, O'Donnell CJ, Wilson JG, Harris TB, Kavousi M, Cupples LA, Rotter JI, Fornage M, Becker LC, Peyser PA, Borecki IB, Reilly MP
BMC medical genetics1475(2013 Jul)

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.
Saito A, Kawamoto M, Kamatani N
Journal of human genetics54(6)317-23(2009 Jun)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

cDNA cloning and expression of a human aldehyde dehydrogenase (ALDH) active with 9-cis-retinal and identification of a rat ortholog, ALDH12.
Lin M, Napoli JL
The Journal of biological chemistry275(51)40106-12(2000 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ALDH8A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALDH8A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09340	NM_170771.3 Latest version!	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu09488	NM_001193480.2 Latest version!	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu18324	NM_022568.4 Latest version!	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
View Old Accession Versions >>
OHu09340	NM_170771.2	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu18324	NM_022568.3	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
OHu09488	NM_001193480.1	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ALDH8A1 ( NM_170771.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_739577.1 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09340
Clone ID Related Accession (Same CDS sequence)	NM_170771.3 , NM_170771.2
Accession Version	NM_170771.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Homo sapiens(human)
Product	2-aminomuconic semialdehyde dehydrogenase isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK074266.1, AK290784.1, BX647324.1 and BF590409.1. On May 31, 2019 this sequence version replaced NM_170771.2. Transcript Variant: This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter protein (isoform 2), that is missing an internal segment compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK074266.1, SRR5189664.87762.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG TCAGAAGTTA CGTCAAGAGA GCTCTTGCTG AAGGTGCCCA AATTTGGTGC 
GGTGAGGGAG TGGATAAGTT GAGCCTCCCT GCCAGGAACC AGGCAGGCTA CTTTATGCTT 
CCCACGGTGA TAACAGACAT TAAGGATGAA TCCTGCTGCA TGACGGAAGA GATATTTGGT 
CCAGTGACGT GTGTCGTCCC CTTTGATAGT GAAGAGGAGG TGATTGAAAG AGCCAACAAC 
GTTAAGTATG GGCTGGCGGC TACCGTGTGG TCCAGCAATG TGGGGCGCGT CCACCGGGTG 
GCTAAGAAGC TGCAGTCTGG CTTGGTCTGG ACCAACTGCT GGCTCATCAG GGAGCTGAAC 
CTTCCTTTCG GGGGGATGAA GAGTTCTGGA ATAGGTAGAG AGGGAGCCAA GGACTCTTAC 
GACTTCTTCA CTGAGATCAA AACCATCACC GTTAAACACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_739577.1
CDS	49..1350
Translation	MAGTNALLMLENFIDGKFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITVKH

Target ORF information:

RefSeq Version	NM_170771.3
Organism	Homo sapiens(human)
Definition	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_170771.3

ORF Insert Sequence:

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG TCAGAAGTTA CGTCAAGAGA GCTCTTGCTG AAGGTGCCCA AATTTGGTGC 
GGTGAGGGAG TGGATAAGTT GAGCCTCCCT GCCAGGAACC AGGCAGGCTA CTTTATGCTT 
CCCACGGTGA TAACAGACAT TAAGGATGAA TCCTGCTGCA TGACGGAAGA GATATTTGGT 
CCAGTGACGT GTGTCGTCCC CTTTGATAGT GAAGAGGAGG TGATTGAAAG AGCCAACAAC 
GTTAAGTATG GGCTGGCGGC TACCGTGTGG TCCAGCAATG TGGGGCGCGT CCACCGGGTG 
GCTAAGAAGC TGCAGTCTGG CTTGGTCTGG ACCAACTGCT GGCTCATCAG GGAGCTGAAC 
CTTCCTTTCG GGGGGATGAA GAGTTCTGGA ATAGGTAGAG AGGGAGCCAA GGACTCTTAC 
GACTTCTTCA CTGAGATCAA AACCATCACC GTTAAACACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALDH8A1 ( NM_170771.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_739577.1 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09340
Clone ID Related Accession (Same CDS sequence)	NM_170771.3 , NM_170771.2
Accession Version	NM_170771.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550678400000
Organism	Homo sapiens(human)
Product	2-aminomuconic semialdehyde dehydrogenase isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA635162.1, AK074266.1, AK290784.1, BX647324.1 and BF590409.1. On Jul 28, 2010 this sequence version replaced NM_170771.1. Transcript Variant: This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter protein (isoform 2), that is missing an internal segment compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK074266.1, AK222848.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG TCAGAAGTTA CGTCAAGAGA GCTCTTGCTG AAGGTGCCCA AATTTGGTGC 
GGTGAGGGAG TGGATAAGTT GAGCCTCCCT GCCAGGAACC AGGCAGGCTA CTTTATGCTT 
CCCACGGTGA TAACAGACAT TAAGGATGAA TCCTGCTGCA TGACGGAAGA GATATTTGGT 
CCAGTGACGT GTGTCGTCCC CTTTGATAGT GAAGAGGAGG TGATTGAAAG AGCCAACAAC 
GTTAAGTATG GGCTGGCGGC TACCGTGTGG TCCAGCAATG TGGGGCGCGT CCACCGGGTG 
GCTAAGAAGC TGCAGTCTGG CTTGGTCTGG ACCAACTGCT GGCTCATCAG GGAGCTGAAC 
CTTCCTTTCG GGGGGATGAA GAGTTCTGGA ATAGGTAGAG AGGGAGCCAA GGACTCTTAC 
GACTTCTTCA CTGAGATCAA AACCATCACC GTTAAACACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_739577.1
CDS	70..1371
Translation	MAGTNALLMLENFIDGKFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITVKH

Target ORF information:

RefSeq Version	NM_170771.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_170771.2

ORF Insert Sequence:

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG TCAGAAGTTA CGTCAAGAGA GCTCTTGCTG AAGGTGCCCA AATTTGGTGC 
GGTGAGGGAG TGGATAAGTT GAGCCTCCCT GCCAGGAACC AGGCAGGCTA CTTTATGCTT 
CCCACGGTGA TAACAGACAT TAAGGATGAA TCCTGCTGCA TGACGGAAGA GATATTTGGT 
CCAGTGACGT GTGTCGTCCC CTTTGATAGT GAAGAGGAGG TGATTGAAAG AGCCAACAAC 
GTTAAGTATG GGCTGGCGGC TACCGTGTGG TCCAGCAATG TGGGGCGCGT CCACCGGGTG 
GCTAAGAAGC TGCAGTCTGG CTTGGTCTGG ACCAACTGCT GGCTCATCAG GGAGCTGAAC 
CTTCCTTTCG GGGGGATGAA GAGTTCTGGA ATAGGTAGAG AGGGAGCCAA GGACTCTTAC 
GACTTCTTCA CTGAGATCAA AACCATCACC GTTAAACACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALDH8A1 ( NM_001193480.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001180409.1 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu09488
Clone ID Related Accession (Same CDS sequence)	NM_001193480.2 , NM_001193480.1
Accession Version	NM_001193480.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1314bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Homo sapiens(human)
Product	2-aminomuconic semialdehyde dehydrogenase isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA635162.1, AK298325.1, BX647324.1 and BF590409.1. On May 31, 2019 this sequence version replaced NM_001193480.1. Transcript Variant: This variant (3) lacks an alternate, in-frame, coding region segment, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK298325.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGGTGTTCCA CCAGGTGTGG TCAATATTGT GTTTGGAACC 
GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC CACCCAGAGG TGCCCCTGAT CTCCTTCACC 
GGGAGCCAGC CCACCGCTGA GCGGATCACC CAGCTGAGCG CTCCCCACTG CAAAAAGCTC 
TCCCTGGAGC TGGGGGGCAA GAATCCTGCC ATCATCTTTG AGGACGCCAA CCTGGATGAG 
TGCATTCCGG CAACCGTCAG GTCCAGCTTT GCCAACCAGG GTGAAATCTG TCTCTGTACC 
AGCAGGATCT TTGTCCAGAA GAGCATCTAT AGTGAATTTT TAAAGAGATT TGTAGAAGCT 
ACCAGAAAGT GGAAAGTCGG CATTCCCTCT GATCCACTGG TGAGCATAGG TGCTCTGATA 
AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT TACGTCAAGA GAGCTCTTGC TGAAGGTGCC 
CAAATTTGGT GCGGTGAGGG AGTGGATAAG TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC 
TACTTTATGC TTCCCACGGT GATAACAGAC ATTAAGGATG AATCCTGCTG CATGACGGAA 
GAGATATTTG GTCCAGTGAC GTGTGTCGTC CCCTTTGATA GTGAAGAGGA GGTGATTGAA 
AGAGCCAACA ACGTTAAGTA TGGGCTGGCG GCTACCGTGT GGTCCAGCAA TGTGGGGCGC 
GTCCACCGGG TGGCTAAGAA GCTGCAGTCT GGCTTGGTCT GGACCAACTG CTGGCTCATC 
AGGGAGCTGA ACCTTCCTTT CGGGGGGATG AAGAGTTCTG GAATAGGTAG AGAGGGAGCC 
AAGGACTCTT ACGACTTCTT CACTGAGATC AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001180409.1
CDS	49..1362
Translation	MAGTNALLMLENFIDGKFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMHYTVRAPVGVGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITVKH

Target ORF information:

RefSeq Version	NM_001193480.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001193480.2

ORF Insert Sequence:

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGGTGTTCCA CCAGGTGTGG TCAATATTGT GTTTGGAACC 
GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC CACCCAGAGG TGCCCCTGAT CTCCTTCACC 
GGGAGCCAGC CCACCGCTGA GCGGATCACC CAGCTGAGCG CTCCCCACTG CAAAAAGCTC 
TCCCTGGAGC TGGGGGGCAA GAATCCTGCC ATCATCTTTG AGGACGCCAA CCTGGATGAG 
TGCATTCCGG CAACCGTCAG GTCCAGCTTT GCCAACCAGG GTGAAATCTG TCTCTGTACC 
AGCAGGATCT TTGTCCAGAA GAGCATCTAT AGTGAATTTT TAAAGAGATT TGTAGAAGCT 
ACCAGAAAGT GGAAAGTCGG CATTCCCTCT GATCCACTGG TGAGCATAGG TGCTCTGATA 
AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT TACGTCAAGA GAGCTCTTGC TGAAGGTGCC 
CAAATTTGGT GCGGTGAGGG AGTGGATAAG TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC 
TACTTTATGC TTCCCACGGT GATAACAGAC ATTAAGGATG AATCCTGCTG CATGACGGAA 
GAGATATTTG GTCCAGTGAC GTGTGTCGTC CCCTTTGATA GTGAAGAGGA GGTGATTGAA 
AGAGCCAACA ACGTTAAGTA TGGGCTGGCG GCTACCGTGT GGTCCAGCAA TGTGGGGCGC 
GTCCACCGGG TGGCTAAGAA GCTGCAGTCT GGCTTGGTCT GGACCAACTG CTGGCTCATC 
AGGGAGCTGA ACCTTCCTTT CGGGGGGATG AAGAGTTCTG GAATAGGTAG AGAGGGAGCC 
AAGGACTCTT ACGACTTCTT CACTGAGATC AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALDH8A1 ( NM_001193480.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001180409.1 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 3, mRNA.

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CloneID	OHu09488
Clone ID Related Accession (Same CDS sequence)	NM_001193480.2 , NM_001193480.1
Accession Version	NM_001193480.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1314bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550678400000
Organism	Homo sapiens(human)
Product	2-aminomuconic semialdehyde dehydrogenase isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA635162.1, AK298325.1, BX647324.1 and BF590409.1. Transcript Variant: This variant (3) lacks an alternate, in-frame, coding region segment, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK298325.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGGTGTTCCA CCAGGTGTGG TCAATATTGT GTTTGGAACC 
GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC CACCCAGAGG TGCCCCTGAT CTCCTTCACC 
GGGAGCCAGC CCACCGCTGA GCGGATCACC CAGCTGAGCG CTCCCCACTG CAAAAAGCTC 
TCCCTGGAGC TGGGGGGCAA GAATCCTGCC ATCATCTTTG AGGACGCCAA CCTGGATGAG 
TGCATTCCGG CAACCGTCAG GTCCAGCTTT GCCAACCAGG GTGAAATCTG TCTCTGTACC 
AGCAGGATCT TTGTCCAGAA GAGCATCTAT AGTGAATTTT TAAAGAGATT TGTAGAAGCT 
ACCAGAAAGT GGAAAGTCGG CATTCCCTCT GATCCACTGG TGAGCATAGG TGCTCTGATA 
AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT TACGTCAAGA GAGCTCTTGC TGAAGGTGCC 
CAAATTTGGT GCGGTGAGGG AGTGGATAAG TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC 
TACTTTATGC TTCCCACGGT GATAACAGAC ATTAAGGATG AATCCTGCTG CATGACGGAA 
GAGATATTTG GTCCAGTGAC GTGTGTCGTC CCCTTTGATA GTGAAGAGGA GGTGATTGAA 
AGAGCCAACA ACGTTAAGTA TGGGCTGGCG GCTACCGTGT GGTCCAGCAA TGTGGGGCGC 
GTCCACCGGG TGGCTAAGAA GCTGCAGTCT GGCTTGGTCT GGACCAACTG CTGGCTCATC 
AGGGAGCTGA ACCTTCCTTT CGGGGGGATG AAGAGTTCTG GAATAGGTAG AGAGGGAGCC 
AAGGACTCTT ACGACTTCTT CACTGAGATC AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001180409.1
CDS	70..1383
Translation	MAGTNALLMLENFIDGKFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMHYTVRAPVGVGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITVKH

Target ORF information:

RefSeq Version	NM_001193480.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001193480.1

ORF Insert Sequence:

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGGTGTTCCA CCAGGTGTGG TCAATATTGT GTTTGGAACC 
GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC CACCCAGAGG TGCCCCTGAT CTCCTTCACC 
GGGAGCCAGC CCACCGCTGA GCGGATCACC CAGCTGAGCG CTCCCCACTG CAAAAAGCTC 
TCCCTGGAGC TGGGGGGCAA GAATCCTGCC ATCATCTTTG AGGACGCCAA CCTGGATGAG 
TGCATTCCGG CAACCGTCAG GTCCAGCTTT GCCAACCAGG GTGAAATCTG TCTCTGTACC 
AGCAGGATCT TTGTCCAGAA GAGCATCTAT AGTGAATTTT TAAAGAGATT TGTAGAAGCT 
ACCAGAAAGT GGAAAGTCGG CATTCCCTCT GATCCACTGG TGAGCATAGG TGCTCTGATA 
AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT TACGTCAAGA GAGCTCTTGC TGAAGGTGCC 
CAAATTTGGT GCGGTGAGGG AGTGGATAAG TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC 
TACTTTATGC TTCCCACGGT GATAACAGAC ATTAAGGATG AATCCTGCTG CATGACGGAA 
GAGATATTTG GTCCAGTGAC GTGTGTCGTC CCCTTTGATA GTGAAGAGGA GGTGATTGAA 
AGAGCCAACA ACGTTAAGTA TGGGCTGGCG GCTACCGTGT GGTCCAGCAA TGTGGGGCGC 
GTCCACCGGG TGGCTAAGAA GCTGCAGTCT GGCTTGGTCT GGACCAACTG CTGGCTCATC 
AGGGAGCTGA ACCTTCCTTT CGGGGGGATG AAGAGTTCTG GAATAGGTAG AGAGGGAGCC 
AAGGACTCTT ACGACTTCTT CACTGAGATC AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALDH8A1 ( NM_022568.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_072090.1 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18324
Clone ID Related Accession (Same CDS sequence)	NM_022568.4 , NM_022568.3
Accession Version	NM_022568.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1464bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1566316800000
Organism	Homo sapiens(human)
Product	2-aminomuconic semialdehyde dehydrogenase isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF303134.1, BX647324.1 and BF590409.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_022568.3. Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer protein (isoform 1). ##Evidence-Data-START## Transcript exon combination :: AF303134.1, ERR279862.3397.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265605.7/ ENSP00000265605.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG GTGAAATCTG TCTCTGTACC AGCAGGATCT TTGTCCAGAA GAGCATCTAT 
AGTGAATTTT TAAAGAGATT TGTAGAAGCT ACCAGAAAGT GGAAAGTCGG CATTCCCTCT 
GATCCACTGG TGAGCATAGG TGCTCTGATA AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT 
TACGTCAAGA GAGCTCTTGC TGAAGGTGCC CAAATTTGGT GCGGTGAGGG AGTGGATAAG 
TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC TACTTTATGC TTCCCACGGT GATAACAGAC 
ATTAAGGATG AATCCTGCTG CATGACGGAA GAGATATTTG GTCCAGTGAC GTGTGTCGTC 
CCCTTTGATA GTGAAGAGGA GGTGATTGAA AGAGCCAACA ACGTTAAGTA TGGGCTGGCG 
GCTACCGTGT GGTCCAGCAA TGTGGGGCGC GTCCACCGGG TGGCTAAGAA GCTGCAGTCT 
GGCTTGGTCT GGACCAACTG CTGGCTCATC AGGGAGCTGA ACCTTCCTTT CGGGGGGATG 
AAGAGTTCTG GAATAGGTAG AGAGGGAGCC AAGGACTCTT ACGACTTCTT CACTGAGATC 
AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_072090.1
CDS	49..1512
Translation	MAGTNALLMLENFIDGKFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITVKH

Target ORF information:

RefSeq Version	NM_022568.4
Organism	Homo sapiens(human)
Definition	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022568.4

ORF Insert Sequence:

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG GTGAAATCTG TCTCTGTACC AGCAGGATCT TTGTCCAGAA GAGCATCTAT 
AGTGAATTTT TAAAGAGATT TGTAGAAGCT ACCAGAAAGT GGAAAGTCGG CATTCCCTCT 
GATCCACTGG TGAGCATAGG TGCTCTGATA AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT 
TACGTCAAGA GAGCTCTTGC TGAAGGTGCC CAAATTTGGT GCGGTGAGGG AGTGGATAAG 
TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC TACTTTATGC TTCCCACGGT GATAACAGAC 
ATTAAGGATG AATCCTGCTG CATGACGGAA GAGATATTTG GTCCAGTGAC GTGTGTCGTC 
CCCTTTGATA GTGAAGAGGA GGTGATTGAA AGAGCCAACA ACGTTAAGTA TGGGCTGGCG 
GCTACCGTGT GGTCCAGCAA TGTGGGGCGC GTCCACCGGG TGGCTAAGAA GCTGCAGTCT 
GGCTTGGTCT GGACCAACTG CTGGCTCATC AGGGAGCTGA ACCTTCCTTT CGGGGGGATG 
AAGAGTTCTG GAATAGGTAG AGAGGGAGCC AAGGACTCTT ACGACTTCTT CACTGAGATC 
AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALDH8A1 ( NM_022568.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_072090.1 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18324
Clone ID Related Accession (Same CDS sequence)	NM_022568.4 , NM_022568.3
Accession Version	NM_022568.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1464bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	aldehyde dehydrogenase family 8 member A1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA635162.1, AF303134.1, BX647324.1 and BF590409.1. This sequence is a reference standard in the RefSeqGene project. On Jul 28, 2010 this sequence version replaced NM_022568.2. Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer protein (isoform 1). ##Evidence-Data-START## Transcript exon combination :: AF303134.1, ERR279862.3397.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG GTGAAATCTG TCTCTGTACC AGCAGGATCT TTGTCCAGAA GAGCATCTAT 
AGTGAATTTT TAAAGAGATT TGTAGAAGCT ACCAGAAAGT GGAAAGTCGG CATTCCCTCT 
GATCCACTGG TGAGCATAGG TGCTCTGATA AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT 
TACGTCAAGA GAGCTCTTGC TGAAGGTGCC CAAATTTGGT GCGGTGAGGG AGTGGATAAG 
TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC TACTTTATGC TTCCCACGGT GATAACAGAC 
ATTAAGGATG AATCCTGCTG CATGACGGAA GAGATATTTG GTCCAGTGAC GTGTGTCGTC 
CCCTTTGATA GTGAAGAGGA GGTGATTGAA AGAGCCAACA ACGTTAAGTA TGGGCTGGCG 
GCTACCGTGT GGTCCAGCAA TGTGGGGCGC GTCCACCGGG TGGCTAAGAA GCTGCAGTCT 
GGCTTGGTCT GGACCAACTG CTGGCTCATC AGGGAGCTGA ACCTTCCTTT CGGGGGGATG 
AAGAGTTCTG GAATAGGTAG AGAGGGAGCC AAGGACTCTT ACGACTTCTT CACTGAGATC 
AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_072090.1
CDS	70..1533
Translation	MAGTNALLMLENFIDGKFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITVKH

Target ORF information:

RefSeq Version	NM_022568.3
Organism	Homo sapiens(human)
Definition	Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022568.3

ORF Insert Sequence:

ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG GTGAAATCTG TCTCTGTACC AGCAGGATCT TTGTCCAGAA GAGCATCTAT 
AGTGAATTTT TAAAGAGATT TGTAGAAGCT ACCAGAAAGT GGAAAGTCGG CATTCCCTCT 
GATCCACTGG TGAGCATAGG TGCTCTGATA AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT 
TACGTCAAGA GAGCTCTTGC TGAAGGTGCC CAAATTTGGT GCGGTGAGGG AGTGGATAAG 
TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC TACTTTATGC TTCCCACGGT GATAACAGAC 
ATTAAGGATG AATCCTGCTG CATGACGGAA GAGATATTTG GTCCAGTGAC GTGTGTCGTC 
CCCTTTGATA GTGAAGAGGA GGTGATTGAA AGAGCCAACA ACGTTAAGTA TGGGCTGGCG 
GCTACCGTGT GGTCCAGCAA TGTGGGGCGC GTCCACCGGG TGGCTAAGAA GCTGCAGTCT 
GGCTTGGTCT GGACCAACTG CTGGCTCATC AGGGAGCTGA ACCTTCCTTT CGGGGGGATG 
AAGAGTTCTG GAATAGGTAG AGAGGGAGCC AAGGACTCTT ACGACTTCTT CACTGAGATC 
AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Reassignment of the human aldehyde dehydrogenase ALDH8A1 (ALDH12) to the kynurenine pathway in tryptophan catabolism.
The Journal of biological chemistry293(25)9594-9603(2018 06)
Davis I,Yang Y,Wherritt D,Liu A

Genetics of coronary artery calcification among African Americans, a meta-analysis.
BMC medical genetics1475(2013 Jul)
Wojczynski MK,Li M,Bielak LF,Kerr KF,Reiner AP,Wong ND,Yanek LR,Qu L,White CC,Lange LA,Ferguson JF,He J,Young T,Mosley TH,Smith JA,Kral BG,Guo X,Wong Q,Ganesh SK,Heckbert SR,Griswold ME,O'Leary DH,Budoff M,Carr JJ,Taylor HA Jr,Bluemke DA,Demissie S,Hwang SJ,Paltoo DN,Polak JF,Psaty BM,Becker DM,Province MA,Post WS,O'Donnell CJ,Wilson JG,Harris TB,Kavousi M,Cupples LA,Rotter JI,Fornage M,Becker LC,Peyser PA,Borecki IB,Reilly MP

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.
Journal of human genetics54(6)317-23(2009 Jun)
Saito A,Kawamoto M,Kamatani N

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

cDNA cloning and expression of a human aldehyde dehydrogenase (ALDH) active with 9-cis-retinal and identification of a rat ortholog, ALDH12.
The Journal of biological chemistry275(51)40106-12(2000 Dec)
Lin M,Napoli JL

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ALDH8A1 cDNA ORF clone, Homo sapiens(human)

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