SDC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SDC2
Entrez Gene ID	6383
Full Name	syndecan 2
Synonyms	CD362,HSPG,HSPG1,SYND2
General protein information	Preferred Names syndecan 2 Names syndecan-2 cell surface-associated heparan sulfate proteoglycan 1 fibroglycan heparan sulfate proteoglycan 1, cell surface-associated heparan sulfate proteoglycan core protein syndecan proteoglycan 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q22.1
Summary	The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008].
Disorder MIM:	142460

mRNA and Protein(s)

mRNA	Protein	Name
NM_002998.3	NP_002989.2	syndecan-2 precursor
NM_002998.4	NP_002989.2	syndecan-2 precursor
XM_024447228.1	XP_024302996.1	syndecan-2 isoform X1
XM_011517212.2	XP_011515514.1	syndecan-2 isoform X1
XM_011517212.3	XP_011515514.1	syndecan-2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SDC2	NP_002989.2
Rattus norvegicus (Norway rat)	Sdc2	NP_037214.1
Pan troglodytes (chimpanzee)	SDC2	XP_003311905.1
Bos taurus (cattle)	SDC2	NP_001029960.2
Canis lupus familiaris (dog)	SDC2	XP_005638221.1
Gallus gallus (chicken)	SDC2	NP_001001462.1
Danio rerio (zebrafish)	sdc2	NP_775330.2
Xenopus tropicalis (tropical clawed frog)	sdc2	NP_001017163.1
Macaca mulatta (Rhesus monkey)	SDC2	XP_002805455.1
Mus musculus (house mouse)	Sdc2	NP_032330.1

Gene Ontology
Bibliography

Related articles in PubMed

Emerging roles of syndecan 2 in epithelial and mesenchymal cancer progression.
Mytilinaiou M, Nikitovic D, Berdiaki A, Kostouras A, Papoutsidakis A, Tsatsakis AM, Tzanakakis GN
IUBMB life69(11)824-833(2017 11)

Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples.
Barták BK, Kalmár A, Péterfia B, Patai ÁV, Galamb O, Valcz G, Spisák S, Wichmann B, Nagy ZB, Tóth K, Tulassay Z, Igaz P, Molnár B
Epigenetics12(9)751-763(2017 09)

Syndecan-2 enhances E-cadherin shedding and fibroblast-like morphological changes by inducing MMP-7 expression in colon cancer cells.
Jang B, Jung H, Chung H, Moon BI, Oh ES
Biochemical and biophysical research communications477(1)47-53(2016 08)

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Barallobre-Barreiro J, Oklu R, Lynch M, Fava M, Baig F, Yin X, Barwari T, Potier DN, Albadawi H, Jahangiri M, Porter KE, Watkins MT, Misra S, Stoughton J, Mayr M
Cardiovascular research110(3)419-30(2016 06)

[Role of syndecan-2 in amyloid plaque formation].
Leonova EI, Galzitskaia OV
Molekuliarnaia biologiia49(1)89-98(2015 Jan-Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SDC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SDC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26958	NM_002998.4 Latest version!	Homo sapiens syndecan 2 (SDC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu42550	XM_011517212.3 Latest version!	Homo sapiens syndecan 2 (SDC2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu42550	XM_024447228.1 Latest version!	Homo sapiens syndecan 2 (SDC2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu26958	NM_002998.3	Homo sapiens syndecan 2 (SDC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu42550	XM_011517212.2	Homo sapiens syndecan 2 (SDC2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SDC2 ( NM_002998.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002989.2 Homo sapiens syndecan 2 (SDC2), mRNA.

Price & Availability↑

CloneID	OHu26958
Clone ID Related Accession (Same CDS sequence)	NM_002998.3 , NM_002998.4
Accession Version	NM_002998.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514217600000
Organism	Homo sapiens(human)
Product	syndecan-2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CK825252.1, BC049836.1, BC030133.2 and AA114891.1. On Nov 22, 2004 this sequence version replaced NM_002998.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.246588.1, BC030133.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGGCGCG CGTGGATCCT GCTCACCTTG GGCTTGGTGG CCTGCGTGTC GGCGGAGTCG 
AGAGCAGAGC TGACATCTGA TAAAGACATG TACCTTGACA ACAGCTCCAT TGAAGAAGCT 
TCAGGAGTGT ATCCTATTGA TGACGATGAC TACGCTTCTG CGTCTGGCTC GGGAGCTGAT 
GAGGATGTAG AGAGTCCAGA GCTGACAACA TCTCGACCAC TTCCAAAGAT ACTGTTGACT 
AGTGCTGCTC CAAAAGTGGA AACCACGACG CTGAATATAC AGAACAAGAT ACCTGCTCAG 
ACAAAGTCAC CTGAAGAAAC TGATAAAGAG AAAGTTCACC TCTCTGACTC AGAAAGGAAA 
ATGGACCCAG CCGAAGAGGA TACAAATGTG TATACTGAGA AACACTCAGA CAGTCTGTTT 
AAACGGACAG AAGTCCTAGC AGCTGTCATT GCTGGTGGAG TTATTGGCTT TCTCTTTGCA 
ATTTTTCTTA TCCTGCTGTT GGTGTATCGC ATGAGAAAGA AGGATGAAGG AAGCTATGAC 
CTTGGAGAAC GCAAACCATC CAGTGCTGCT TATCAGAAGG CACCTACTAA GGAGTTTTAT 
GCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002989.2
CDS	619..1224
Translation	MRRAWILLTLGLVACVSAESRAELTSDKDMYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA

Target ORF information:

RefSeq Version	NM_002998.3
Organism	Homo sapiens(human)
Definition	Homo sapiens syndecan 2 (SDC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002998.3

ORF Insert Sequence:

ATGCGGCGCG CGTGGATCCT GCTCACCTTG GGCTTGGTGG CCTGCGTGTC GGCGGAGTCG 
AGAGCAGAGC TGACATCTGA TAAAGACATG TACCTTGACA ACAGCTCCAT TGAAGAAGCT 
TCAGGAGTGT ATCCTATTGA TGACGATGAC TACGCTTCTG CGTCTGGCTC GGGAGCTGAT 
GAGGATGTAG AGAGTCCAGA GCTGACAACA TCTCGACCAC TTCCAAAGAT ACTGTTGACT 
AGTGCTGCTC CAAAAGTGGA AACCACGACG CTGAATATAC AGAACAAGAT ACCTGCTCAG 
ACAAAGTCAC CTGAAGAAAC TGATAAAGAG AAAGTTCACC TCTCTGACTC AGAAAGGAAA 
ATGGACCCAG CCGAAGAGGA TACAAATGTG TATACTGAGA AACACTCAGA CAGTCTGTTT 
AAACGGACAG AAGTCCTAGC AGCTGTCATT GCTGGTGGAG TTATTGGCTT TCTCTTTGCA 
ATTTTTCTTA TCCTGCTGTT GGTGTATCGC ATGAGAAAGA AGGATGAAGG AAGCTATGAC 
CTTGGAGAAC GCAAACCATC CAGTGCTGCT TATCAGAAGG CACCTACTAA GGAGTTTTAT 
GCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SDC2 ( NM_002998.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002989.2 Homo sapiens syndecan 2 (SDC2), mRNA.

Price & Availability↑

CloneID	OHu26958
Clone ID Related Accession (Same CDS sequence)	NM_002998.3 , NM_002998.4
Accession Version	NM_002998.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569427200000
Organism	Homo sapiens(human)
Product	syndecan-2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CK825252.1, BC049836.1, BC030133.2 and AA114891.1. On Nov 23, 2018 this sequence version replaced NM_002998.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.250362.1, SRR1660809.243341.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000302190.9/ ENSP00000307046.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCGGCGCG CGTGGATCCT GCTCACCTTG GGCTTGGTGG CCTGCGTGTC GGCGGAGTCG 
AGAGCAGAGC TGACATCTGA TAAAGACATG TACCTTGACA ACAGCTCCAT TGAAGAAGCT 
TCAGGAGTGT ATCCTATTGA TGACGATGAC TACGCTTCTG CGTCTGGCTC GGGAGCTGAT 
GAGGATGTAG AGAGTCCAGA GCTGACAACA TCTCGACCAC TTCCAAAGAT ACTGTTGACT 
AGTGCTGCTC CAAAAGTGGA AACCACGACG CTGAATATAC AGAACAAGAT ACCTGCTCAG 
ACAAAGTCAC CTGAAGAAAC TGATAAAGAG AAAGTTCACC TCTCTGACTC AGAAAGGAAA 
ATGGACCCAG CCGAAGAGGA TACAAATGTG TATACTGAGA AACACTCAGA CAGTCTGTTT 
AAACGGACAG AAGTCCTAGC AGCTGTCATT GCTGGTGGAG TTATTGGCTT TCTCTTTGCA 
ATTTTTCTTA TCCTGCTGTT GGTGTATCGC ATGAGAAAGA AGGATGAAGG AAGCTATGAC 
CTTGGAGAAC GCAAACCATC CAGTGCTGCT TATCAGAAGG CACCTACTAA GGAGTTTTAT 
GCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002989.2
CDS	460..1065
Translation	MRRAWILLTLGLVACVSAESRAELTSDKDMYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA

Target ORF information:

RefSeq Version	NM_002998.4
Organism	Homo sapiens(human)
Definition	Homo sapiens syndecan 2 (SDC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002998.4

ORF Insert Sequence:

ATGCGGCGCG CGTGGATCCT GCTCACCTTG GGCTTGGTGG CCTGCGTGTC GGCGGAGTCG 
AGAGCAGAGC TGACATCTGA TAAAGACATG TACCTTGACA ACAGCTCCAT TGAAGAAGCT 
TCAGGAGTGT ATCCTATTGA TGACGATGAC TACGCTTCTG CGTCTGGCTC GGGAGCTGAT 
GAGGATGTAG AGAGTCCAGA GCTGACAACA TCTCGACCAC TTCCAAAGAT ACTGTTGACT 
AGTGCTGCTC CAAAAGTGGA AACCACGACG CTGAATATAC AGAACAAGAT ACCTGCTCAG 
ACAAAGTCAC CTGAAGAAAC TGATAAAGAG AAAGTTCACC TCTCTGACTC AGAAAGGAAA 
ATGGACCCAG CCGAAGAGGA TACAAATGTG TATACTGAGA AACACTCAGA CAGTCTGTTT 
AAACGGACAG AAGTCCTAGC AGCTGTCATT GCTGGTGGAG TTATTGGCTT TCTCTTTGCA 
ATTTTTCTTA TCCTGCTGTT GGTGTATCGC ATGAGAAAGA AGGATGAAGG AAGCTATGAC 
CTTGGAGAAC GCAAACCATC CAGTGCTGCT TATCAGAAGG CACCTACTAA GGAGTTTTAT 
GCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SDC2 ( XM_024447228.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024302996.1 Homo sapiens syndecan 2 (SDC2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu42550
Clone ID Related Accession (Same CDS sequence)	XM_024447228.1 , XM_011517212.2 , XM_011517212.3
Accession Version	XM_024447228.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	syndecan-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACCTTG ACAACAGCTC CATTGAAGAA GCTTCAGGAG TGTATCCTAT TGATGACGAT 
GACTACGCTT CTGCGTCTGG CTCGGGAGCT GATGAGGATG TAGAGAGTCC AGAGCTGACA 
ACATCTCGAC CACTTCCAAA GATACTGTTG ACTAGTGCTG CTCCAAAAGT GGAAACCACG 
ACGCTGAATA TACAGAACAA GATACCTGCT CAGACAAAGT CACCTGAAGA AACTGATAAA 
GAGAAAGTTC ACCTCTCTGA CTCAGAAAGG AAAATGGACC CAGCCGAAGA GGATACAAAT 
GTGTATACTG AGAAACACTC AGACAGTCTG TTTAAACGGA CAGAAGTCCT AGCAGCTGTC 
ATTGCTGGTG GAGTTATTGG CTTTCTCTTT GCAATTTTTC TTATCCTGCT GTTGGTGTAT 
CGCATGAGAA AGAAGGATGA AGGAAGCTAT GACCTTGGAG AACGCAAACC ATCCAGTGCT 
GCTTATCAGA AGGCACCTAC TAAGGAGTTT TATGCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024302996.1
CDS	964..1482
Translation	MYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA

Target ORF information:

RefSeq Version	XM_024447228.1
Organism	Homo sapiens(human)
Definition	Homo sapiens syndecan 2 (SDC2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024447228.1

ORF Insert Sequence:

ATGTACCTTG ACAACAGCTC CATTGAAGAA GCTTCAGGAG TGTATCCTAT TGATGACGAT 
GACTACGCTT CTGCGTCTGG CTCGGGAGCT GATGAGGATG TAGAGAGTCC AGAGCTGACA 
ACATCTCGAC CACTTCCAAA GATACTGTTG ACTAGTGCTG CTCCAAAAGT GGAAACCACG 
ACGCTGAATA TACAGAACAA GATACCTGCT CAGACAAAGT CACCTGAAGA AACTGATAAA 
GAGAAAGTTC ACCTCTCTGA CTCAGAAAGG AAAATGGACC CAGCCGAAGA GGATACAAAT 
GTGTATACTG AGAAACACTC AGACAGTCTG TTTAAACGGA CAGAAGTCCT AGCAGCTGTC 
ATTGCTGGTG GAGTTATTGG CTTTCTCTTT GCAATTTTTC TTATCCTGCT GTTGGTGTAT 
CGCATGAGAA AGAAGGATGA AGGAAGCTAT GACCTTGGAG AACGCAAACC ATCCAGTGCT 
GCTTATCAGA AGGCACCTAC TAAGGAGTTT TATGCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SDC2 ( XM_011517212.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011515514.1 Homo sapiens syndecan 2 (SDC2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu42550
Clone ID Related Accession (Same CDS sequence)	XM_024447228.1 , XM_011517212.2 , XM_011517212.3
Accession Version	XM_011517212.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	syndecan-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011517212.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACCTTG ACAACAGCTC CATTGAAGAA GCTTCAGGAG TGTATCCTAT TGATGACGAT 
GACTACGCTT CTGCGTCTGG CTCGGGAGCT GATGAGGATG TAGAGAGTCC AGAGCTGACA 
ACATCTCGAC CACTTCCAAA GATACTGTTG ACTAGTGCTG CTCCAAAAGT GGAAACCACG 
ACGCTGAATA TACAGAACAA GATACCTGCT CAGACAAAGT CACCTGAAGA AACTGATAAA 
GAGAAAGTTC ACCTCTCTGA CTCAGAAAGG AAAATGGACC CAGCCGAAGA GGATACAAAT 
GTGTATACTG AGAAACACTC AGACAGTCTG TTTAAACGGA CAGAAGTCCT AGCAGCTGTC 
ATTGCTGGTG GAGTTATTGG CTTTCTCTTT GCAATTTTTC TTATCCTGCT GTTGGTGTAT 
CGCATGAGAA AGAAGGATGA AGGAAGCTAT GACCTTGGAG AACGCAAACC ATCCAGTGCT 
GCTTATCAGA AGGCACCTAC TAAGGAGTTT TATGCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011515514.1
CDS	238..756
Translation	MYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA

Target ORF information:

RefSeq Version	XM_011517212.2
Organism	Homo sapiens(human)
Definition	Homo sapiens syndecan 2 (SDC2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011517212.2

ORF Insert Sequence:

ATGTACCTTG ACAACAGCTC CATTGAAGAA GCTTCAGGAG TGTATCCTAT TGATGACGAT 
GACTACGCTT CTGCGTCTGG CTCGGGAGCT GATGAGGATG TAGAGAGTCC AGAGCTGACA 
ACATCTCGAC CACTTCCAAA GATACTGTTG ACTAGTGCTG CTCCAAAAGT GGAAACCACG 
ACGCTGAATA TACAGAACAA GATACCTGCT CAGACAAAGT CACCTGAAGA AACTGATAAA 
GAGAAAGTTC ACCTCTCTGA CTCAGAAAGG AAAATGGACC CAGCCGAAGA GGATACAAAT 
GTGTATACTG AGAAACACTC AGACAGTCTG TTTAAACGGA CAGAAGTCCT AGCAGCTGTC 
ATTGCTGGTG GAGTTATTGG CTTTCTCTTT GCAATTTTTC TTATCCTGCT GTTGGTGTAT 
CGCATGAGAA AGAAGGATGA AGGAAGCTAT GACCTTGGAG AACGCAAACC ATCCAGTGCT 
GCTTATCAGA AGGCACCTAC TAAGGAGTTT TATGCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SDC2 ( XM_011517212.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011515514.1 Homo sapiens syndecan 2 (SDC2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu42550
Clone ID Related Accession (Same CDS sequence)	XM_024447228.1 , XM_011517212.2 , XM_011517212.3
Accession Version	XM_011517212.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	syndecan-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011517212.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACCTTG ACAACAGCTC CATTGAAGAA GCTTCAGGAG TGTATCCTAT TGATGACGAT 
GACTACGCTT CTGCGTCTGG CTCGGGAGCT GATGAGGATG TAGAGAGTCC AGAGCTGACA 
ACATCTCGAC CACTTCCAAA GATACTGTTG ACTAGTGCTG CTCCAAAAGT GGAAACCACG 
ACGCTGAATA TACAGAACAA GATACCTGCT CAGACAAAGT CACCTGAAGA AACTGATAAA 
GAGAAAGTTC ACCTCTCTGA CTCAGAAAGG AAAATGGACC CAGCCGAAGA GGATACAAAT 
GTGTATACTG AGAAACACTC AGACAGTCTG TTTAAACGGA CAGAAGTCCT AGCAGCTGTC 
ATTGCTGGTG GAGTTATTGG CTTTCTCTTT GCAATTTTTC TTATCCTGCT GTTGGTGTAT 
CGCATGAGAA AGAAGGATGA AGGAAGCTAT GACCTTGGAG AACGCAAACC ATCCAGTGCT 
GCTTATCAGA AGGCACCTAC TAAGGAGTTT TATGCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011515514.1
CDS	238..756
Translation	MYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA

Target ORF information:

RefSeq Version	XM_011517212.3
Organism	Homo sapiens(human)
Definition	Homo sapiens syndecan 2 (SDC2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011517212.3

ORF Insert Sequence:

ATGTACCTTG ACAACAGCTC CATTGAAGAA GCTTCAGGAG TGTATCCTAT TGATGACGAT 
GACTACGCTT CTGCGTCTGG CTCGGGAGCT GATGAGGATG TAGAGAGTCC AGAGCTGACA 
ACATCTCGAC CACTTCCAAA GATACTGTTG ACTAGTGCTG CTCCAAAAGT GGAAACCACG 
ACGCTGAATA TACAGAACAA GATACCTGCT CAGACAAAGT CACCTGAAGA AACTGATAAA 
GAGAAAGTTC ACCTCTCTGA CTCAGAAAGG AAAATGGACC CAGCCGAAGA GGATACAAAT 
GTGTATACTG AGAAACACTC AGACAGTCTG TTTAAACGGA CAGAAGTCCT AGCAGCTGTC 
ATTGCTGGTG GAGTTATTGG CTTTCTCTTT GCAATTTTTC TTATCCTGCT GTTGGTGTAT 
CGCATGAGAA AGAAGGATGA AGGAAGCTAT GACCTTGGAG AACGCAAACC ATCCAGTGCT 
GCTTATCAGA AGGCACCTAC TAAGGAGTTT TATGCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Emerging roles of syndecan 2 in epithelial and mesenchymal cancer progression.
IUBMB life69(11)824-833(2017 11)
Mytilinaiou M,Nikitovic D,Berdiaki A,Kostouras A,Papoutsidakis A,Tsatsakis AM,Tzanakakis GN

Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples.
Epigenetics12(9)751-763(2017 09)
Barták BK,Kalmár A,Péterfia B,Patai ÁV,Galamb O,Valcz G,Spisák S,Wichmann B,Nagy ZB,Tóth K,Tulassay Z,Igaz P,Molnár B

Syndecan-2 enhances E-cadherin shedding and fibroblast-like morphological changes by inducing MMP-7 expression in colon cancer cells.
Biochemical and biophysical research communications477(1)47-53(2016 08)
Jang B,Jung H,Chung H,Moon BI,Oh ES

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Cardiovascular research110(3)419-30(2016 06)
Barallobre-Barreiro J,Oklu R,Lynch M,Fava M,Baig F,Yin X,Barwari T,Potier DN,Albadawi H,Jahangiri M,Porter KE,Watkins MT,Misra S,Stoughton J,Mayr M

[Role of syndecan-2 in amyloid plaque formation].
Molekuliarnaia biologiia49(1)89-98(2015 Jan-Feb)
Leonova EI,Galzitskaia OV

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SDC2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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