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Home » Protein Expression » TurboCHO™ or Nothing » TurboCHO™ Express Platform
GenScript has developed the proprietary TurboCHO™ expression system for higher-titer production of recombinant antibodies. Unlike TurboCHO™ High throughput platform, TurboCHO™ Express is designed for middle-scale production, with a timeline from gene synthesis to antibody delivery of just 10 business days! It also offers multiple purification and endotoxin control options in the default QC list, ensuring high-quality product delivery. TurboCHO™ Express platform can also deliver a range of purified antibody products (e.g., IgGs, Fab, scFV, VHH, bi-specific antibodies, and more) in quantities (i.e., from 5 mg to 1 g).
Additionally, GenScript introduces the FucoFree Cell line, designed for the production of afucosylated antibodies. This innovative cell line eliminates fucose modification, resulting in enhanced antibody-dependent cellular cytotoxicity (ADCC) and improved therapeutic efficacy. The combination of TurboCHO™ Express and the FucoFree Cell line provides researchers with efficient and tailored antibody production, offering new possibilities in the field of antibody therapeutics.
Cost-Effective
Superior Quality
Easy to Scale-up
FucoFree Cell Available
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Note: This customized solution applies to all
types of proteins, antibody species, isotypes, and fragments.
1. All incoming projects are subjected to evaluation.
2. Optional steps are offered with an extra charge upon
request.
3. The 10 business days is decided from sequence evaluation.
Bi-specific Antibody Production – Case 1, Titer: 374 mg/L with Purity > 99%
Bi-specific Antibody Production – Case 2, After purification yield: 65mg/L, Purity (SDS-Page)>95%, Purity (SEC)>93%
Bi-specific Antibody Production – Case 3, After purification yield: 98mg/L, Purity (SDS-Page)>90%, Purity (SEC)>99%
1. Similar expression performance in Fuco free TurboCHO system compared to wild-type TurboCHO!
| No. | Control Titer (mg/L) | Fuco-free Titer (mg/L) | Titer Differences (%) |
|---|---|---|---|
| test-1 | 574 | 577 | 0.50% |
| test-2 | 575 | 612 | 6.07% |
| test-3 | 577 | 565 | -2.08% |
2. Comparable purity in Fuco free TurboCHO system compared to wild-type TurboCHO!
3. No fucosylation modification in Fuco free TurboCHO system compared to wild-type TurboCHO!
| N-Glycan | G0F-GlcNAc | Man 5 | G0F | G1F |
|---|---|---|---|---|
| TurboCHO™ | 15.5% | 10.7% | 65.3% | 8.5% |
| N-Glycan | G0-GlcNAc | Man 5 | G0 | G1 |
| FucoFree TurboCHO™ | 15.0% | 8.9% | 71.2% | 4.9% |
From gene synthesis to antibody delivery starting at 8 BDs
Our customer service representatives are available 24 hours Monday through Friday. You may contact us anytime for assistance. Orders can be placed online, over the phone, by email or fax. Please have your payment information (credit card, purchase order or bank information) ready.
Click the quote button, provide service information and submit
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Your review and approve final order details and price
You provide credit card/PO information and order is placed
Project is initiated inmediately
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