KCNK15 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KCNK15
Entrez Gene ID	60598
Full Name	potassium two pore domain channel subfamily K member 15
Synonyms	K2p15.1,KCNK11,KCNK14,KT3.3,TASK-5,TASK5,dJ781B1.1
General protein information	Preferred Names potassium two pore domain channel subfamily K member 15 Names potassium channel subfamily K member 15 TWIK-related acid-sensitive K(+) channel 5 acid-sensitive potassium channel protein TASK-5 potassium channel, subfamily K, member 14 potassium channel, two pore domain subfamily K, member 15 two pore K(+) channel KT3.3 two pore potassium channel KT3.3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.12
Summary	This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008].
Disorder MIM:	607368

mRNA and Protein(s)

mRNA	Protein	Name
NM_022358.3	NP_071753.2	potassium channel subfamily K member 15 precursor
XM_017028003.1	XP_016883492.1	potassium channel subfamily K member 15 isoform X1
NM_022358.4	NP_071753.2	potassium channel subfamily K member 15 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	KCNK15	NP_071753.2
Canis lupus familiaris (dog)	KCNK15	XP_543011.2
Mus musculus (house mouse)	Kcnk15	NP_001025463.1
Danio rerio (zebrafish)	kcnk15	NP_001104701.1
Rattus norvegicus (Norway rat)	Kcnk15	NP_570826.1
Pan troglodytes (chimpanzee)	KCNK15	XP_001152552.1
Bos taurus (cattle)	KCNK15	NP_001193475.1

Gene Ontology
Bibliography

Related articles in PubMed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)

International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels.
Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S
Pharmacological reviews57(4)527-40(2005 Dec)

The DNA sequence and comparative analysis of human chromosome 20.
Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, Stavrides G, Almeida JP, Babbage AK, Bagguley CL, Bailey J, Barlow KF, Bates KN, Beard LM, Beare DM, Beasley OP, Bird CP, Blakey SE, Bridgeman AM, Brown AJ, Buck D, Burrill W, Butler AP, Carder C, Carter NP, Chapman JC, Clamp M, Clark G, Clark LN, Clark SY, Clee CM, Clegg S, Cobley VE, Collier RE, Connor R, Corby NR, Coulson A, Coville GJ, Deadman R, Dhami P, Dunn M, Ellington AG, Frankland JA, Fraser A, French L, Garner P, Grafham DV, Griffiths C, Griffiths MN, Gwilliam R, Hall RE, Hammond S, Harley JL, Heath PD, Ho S, Holden JL, Howden PJ, Huckle E, Hunt AR, Hunt SE, Jekosch K, Johnson CM, Johnson D, Kay MP, Kimberley AM, King A, Knights A, Laird GK, Lawlor S, Lehvaslaiho MH, Leversha M, Lloyd C, Lloyd DM, Lovell JD, Marsh VL, Martin SL, McConnachie LJ, McLay K, McMurray AA, Milne S, Mistry D, Moore MJ, Mullikin JC, Nickerson T, Oliver K, Parker A, Patel R, Pearce TA, Peck AI, Phillimore BJ, Prathalingam SR, Plumb RW, Ramsay H, Rice CM, Ross MT, Scott CE, Sehra HK, Shownkeen R, Sims S, Skuce CD, Smith ML, Soderlund C, Steward CA, Sulston JE, Swann M, Sycamore N, Taylor R, Tee L, Thomas DW, Thorpe A, Tracey A, Tromans AC, Vaudin M, Wall M, Wallis JM, Whitehead SL, Whittaker P, Willey DL, Williams L, Williams SA, Wilming L, Wray PW, Hubbard T, Durbin RM, Bentley DR, Beck S, Rogers J
Nature414(6866)865-71(2001 Dec 20-27)

Expression pattern in brain of TASK-1, TASK-3, and a tandem pore domain K(+) channel subunit, TASK-5, associated with the central auditory nervous system.
Karschin C, Wischmeyer E, Preisig-Müller R, Rajan S, Derst C, Grzeschik KH, Daut J, Karschin A
Molecular and cellular neurosciences18(6)632-48(2001 Dec)

TASK-5, a novel member of the tandem pore K+ channel family.
Ashmole I, Goodwin PA, Stanfield PR
Pflugers Archiv : European journal of physiology442(6)828-33(2001 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KCNK15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNK15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu93106	XM_017028003.1 Latest version!	Homo sapiens potassium two pore domain channel subfamily K member 15 (KCNK15), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu32340	NM_022358.4 Latest version!	Homo sapiens potassium two pore domain channel subfamily K member 15 (KCNK15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
View Old Accession Versions >>
OHu32340	NM_022358.3	Homo sapiens potassium two pore domain channel subfamily K member 15 (KCNK15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KCNK15 ( XM_017028003.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016883492.1 Homo sapiens potassium two pore domain channel subfamily K member 15 (KCNK15), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu93106
Clone ID Related Accession (Same CDS sequence)	XM_017028003.1
Accession Version	XM_017028003.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	potassium channel subfamily K member 15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCCCG GGCAGGCGAG TGGGAGGCGG ACAGGGGAGC GGTTCTTCCG GCCCCCACCC 
GTGGCGATCC CAGCCTCCAG GTTCCCGGCA GTCGCCCCGC CTCGCCCGTC ACAACCCTGC 
CGCGTGGGGC CGGGGTTGGA GGGGGCGGAG CGCGCGGTCC GGGCACACGG AGCAGGTTGG 
GACCGCGGCG GGTACCGGGG CCGGGGCGCC ATGCGGAGGC CGAGCGTGCG CGCGGCCGGG 
CTGGTCCTGT GCACCCTGTG TTACCTGCTG GTGGGCGCTG CTGTCTTCGA CGCGCTCGAG 
TCCGAGGCGG AAAGCGGCCG CCAGCGACTG CTGGTCCAGA AGCGGGGCGC TCTCCGGAGG 
AAGTTCGGCT TCTCGGCCGA GGACTACCGC GAGCTGGAGC GCCTGGCGCT CCAGGCTGAG 
CCCCACCGCG CCGGCCGCCA GTGGAAGTTC CCCGGCTCCT TCTACTTCGC CATCACCGTC 
ATCACTACCA TCGGGATGCA GAGCAGTTCC TTTGGAGCAT CTGGACCACC AGCTGTTGCC 
ATGACTACCA TCTGGCTGGT ACCTGCTGAG CCTAAACCTG GGGGAACAGG AAGGAGAGAA 
GTGGGCTCTG CAGGGCTCCA GGCTTGGTGC CAGCCACTCC CCAGGCTCCA GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016883492.1
CDS	97..753
Translation	MNPGQASGRRTGERFFRPPPVAIPASRFPAVAPPRPSQPCRVGPGLEGAERAVRAHGAGWDRGGYRGRGAMRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYRELERLALQAEPHRAGRQWKFPGSFYFAITVITTIGMQSSSFGASGPPAVAMTTIWLVPAEPKPGGTGRREVGSAGLQAWCQPLPRLQL

Target ORF information:

RefSeq Version	XM_017028003.1
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium two pore domain channel subfamily K member 15 (KCNK15), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017028003.1

ORF Insert Sequence:

ATGAACCCCG GGCAGGCGAG TGGGAGGCGG ACAGGGGAGC GGTTCTTCCG GCCCCCACCC 
GTGGCGATCC CAGCCTCCAG GTTCCCGGCA GTCGCCCCGC CTCGCCCGTC ACAACCCTGC 
CGCGTGGGGC CGGGGTTGGA GGGGGCGGAG CGCGCGGTCC GGGCACACGG AGCAGGTTGG 
GACCGCGGCG GGTACCGGGG CCGGGGCGCC ATGCGGAGGC CGAGCGTGCG CGCGGCCGGG 
CTGGTCCTGT GCACCCTGTG TTACCTGCTG GTGGGCGCTG CTGTCTTCGA CGCGCTCGAG 
TCCGAGGCGG AAAGCGGCCG CCAGCGACTG CTGGTCCAGA AGCGGGGCGC TCTCCGGAGG 
AAGTTCGGCT TCTCGGCCGA GGACTACCGC GAGCTGGAGC GCCTGGCGCT CCAGGCTGAG 
CCCCACCGCG CCGGCCGCCA GTGGAAGTTC CCCGGCTCCT TCTACTTCGC CATCACCGTC 
ATCACTACCA TCGGGATGCA GAGCAGTTCC TTTGGAGCAT CTGGACCACC AGCTGTTGCC 
ATGACTACCA TCTGGCTGGT ACCTGCTGAG CCTAAACCTG GGGGAACAGG AAGGAGAGAA 
GTGGGCTCTG CAGGGCTCCA GGCTTGGTGC CAGCCACTCC CCAGGCTCCA GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNK15 ( NM_022358.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_071753.2 Homo sapiens potassium two pore domain channel subfamily K member 15 (KCNK15), mRNA.

Price & Availability↑

CloneID	OHu32340
Clone ID Related Accession (Same CDS sequence)	NM_022358.3 , NM_022358.4
Accession Version	NM_022358.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	potassium channel subfamily K member 15 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF257081.1, AF294351.1 and BC082981.1. On May 19, 2011 this sequence version replaced NM_022358.2. ##Evidence-Data-START## Transcript exon combination :: AF257081.1, AF294350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCGGAGGC CGAGCGTGCG CGCGGCCGGG CTGGTCCTGT GCACCCTGTG TTACCTGCTG 
GTGGGCGCTG CTGTCTTCGA CGCGCTCGAG TCCGAGGCGG AAAGCGGCCG CCAGCGACTG 
CTGGTCCAGA AGCGGGGCGC TCTCCGGAGG AAGTTCGGCT TCTCGGCCGA GGACTACCGC 
GAGCTGGAGC GCCTGGCGCT CCAGGCTGAG CCCCACCGCG CCGGCCGCCA GTGGAAGTTC 
CCCGGCTCCT TCTACTTCGC CATCACCGTC ATCACTACCA TCGAGTACGG CCACGCCGCG 
CCGGGTACGG ACTCCGGCAA GGTCTTCTGC ATGTTCTACG CGCTCCTGGG CATCCCGCTG 
ACGCTGGTCA CTTTCCAGAG CCTGGGCGAA CGGCTGAACG CGGTGGTGCG GCGCCTCCTG 
TTGGCGGCCA AGTGCTGCCT GGGCCTGCGG TGGACGTGCG TGTCCACGGA GAACCTGGTG 
GTGGCCGGGC TGCTGGCGTG TGCCGCCACC CTGGCCCTCG GGGCCGTCGC CTTCTCGCAC 
TTCGAGGGCT GGACCTTCTT CCACGCCTAC TACTACTGCT TCATCACCCT CACCACCATC 
GGCTTCGGCG ACTTCGTGGC ACTGCAGAGC GGCGAGGCGC TGCAGAGGAA GCTCCCCTAC 
GTGGCCTTCA GCTTCCTCTA CATCCTCCTG GGGCTCACGG TCATTGGCGC CTTCCTCAAC 
CTGGTGGTCC TGCGCTTCCT CGTTGCCAGC GCCGACTGGC CCGAGCGCGC TGCCCGCACC 
CCCAGCCCGC GCCCCCCGGG GGCGCCCGAG AGCCGTGGCC TCTGGCTGCC CCGCCGCCCG 
GCCCGCTCCG TGGGCTCCGC CTCTGTCTTC TGCCACGTGC ACAAGCTGGA GAGGTGCGCC 
CGCGACAACC TGGGCTTTTC GCCCCCCTCG AGCCCGGGGG TCGTGCGTGG CGGGCAGGCT 
CCCAGGCTTG GGGCCCGGTG GAAGTCCATC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071753.2
CDS	65..1057
Translation	MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYRELERLALQAEPHRAGRQWKFPGSFYFAITVITTIEYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLNLVVLRFLVASADWPERAARTPSPRPPGAPESRGLWLPRRPARSVGSASVFCHVHKLERCARDNLGFSPPSSPGVVRGGQAPRLGARWKSI

Target ORF information:

RefSeq Version	NM_022358.3
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium two pore domain channel subfamily K member 15 (KCNK15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022358.3

ORF Insert Sequence:

ATGCGGAGGC CGAGCGTGCG CGCGGCCGGG CTGGTCCTGT GCACCCTGTG TTACCTGCTG 
GTGGGCGCTG CTGTCTTCGA CGCGCTCGAG TCCGAGGCGG AAAGCGGCCG CCAGCGACTG 
CTGGTCCAGA AGCGGGGCGC TCTCCGGAGG AAGTTCGGCT TCTCGGCCGA GGACTACCGC 
GAGCTGGAGC GCCTGGCGCT CCAGGCTGAG CCCCACCGCG CCGGCCGCCA GTGGAAGTTC 
CCCGGCTCCT TCTACTTCGC CATCACCGTC ATCACTACCA TCGAGTACGG CCACGCCGCG 
CCGGGTACGG ACTCCGGCAA GGTCTTCTGC ATGTTCTACG CGCTCCTGGG CATCCCGCTG 
ACGCTGGTCA CTTTCCAGAG CCTGGGCGAA CGGCTGAACG CGGTGGTGCG GCGCCTCCTG 
TTGGCGGCCA AGTGCTGCCT GGGCCTGCGG TGGACGTGCG TGTCCACGGA GAACCTGGTG 
GTGGCCGGGC TGCTGGCGTG TGCCGCCACC CTGGCCCTCG GGGCCGTCGC CTTCTCGCAC 
TTCGAGGGCT GGACCTTCTT CCACGCCTAC TACTACTGCT TCATCACCCT CACCACCATC 
GGCTTCGGCG ACTTCGTGGC ACTGCAGAGC GGCGAGGCGC TGCAGAGGAA GCTCCCCTAC 
GTGGCCTTCA GCTTCCTCTA CATCCTCCTG GGGCTCACGG TCATTGGCGC CTTCCTCAAC 
CTGGTGGTCC TGCGCTTCCT CGTTGCCAGC GCCGACTGGC CCGAGCGCGC TGCCCGCACC 
CCCAGCCCGC GCCCCCCGGG GGCGCCCGAG AGCCGTGGCC TCTGGCTGCC CCGCCGCCCG 
GCCCGCTCCG TGGGCTCCGC CTCTGTCTTC TGCCACGTGC ACAAGCTGGA GAGGTGCGCC 
CGCGACAACC TGGGCTTTTC GCCCCCCTCG AGCCCGGGGG TCGTGCGTGG CGGGCAGGCT 
CCCAGGCTTG GGGCCCGGTG GAAGTCCATC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNK15 ( NM_022358.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_071753.2 Homo sapiens potassium two pore domain channel subfamily K member 15 (KCNK15), mRNA.

Price & Availability↑

CloneID	OHu32340
Clone ID Related Accession (Same CDS sequence)	NM_022358.3 , NM_022358.4
Accession Version	NM_022358.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577721600000
Organism	Homo sapiens(human)
Product	potassium channel subfamily K member 15 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF257081.1, AF294351.1 and BC082981.1. On Nov 23, 2018 this sequence version replaced NM_022358.3. ##Evidence-Data-START## Transcript exon combination :: AF257081.1, AF294350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000372861.5/ ENSP00000361952.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCGGAGGC CGAGCGTGCG CGCGGCCGGG CTGGTCCTGT GCACCCTGTG TTACCTGCTG 
GTGGGCGCTG CTGTCTTCGA CGCGCTCGAG TCCGAGGCGG AAAGCGGCCG CCAGCGACTG 
CTGGTCCAGA AGCGGGGCGC TCTCCGGAGG AAGTTCGGCT TCTCGGCCGA GGACTACCGC 
GAGCTGGAGC GCCTGGCGCT CCAGGCTGAG CCCCACCGCG CCGGCCGCCA GTGGAAGTTC 
CCCGGCTCCT TCTACTTCGC CATCACCGTC ATCACTACCA TCGAGTACGG CCACGCCGCG 
CCGGGTACGG ACTCCGGCAA GGTCTTCTGC ATGTTCTACG CGCTCCTGGG CATCCCGCTG 
ACGCTGGTCA CTTTCCAGAG CCTGGGCGAA CGGCTGAACG CGGTGGTGCG GCGCCTCCTG 
TTGGCGGCCA AGTGCTGCCT GGGCCTGCGG TGGACGTGCG TGTCCACGGA GAACCTGGTG 
GTGGCCGGGC TGCTGGCGTG TGCCGCCACC CTGGCCCTCG GGGCCGTCGC CTTCTCGCAC 
TTCGAGGGCT GGACCTTCTT CCACGCCTAC TACTACTGCT TCATCACCCT CACCACCATC 
GGCTTCGGCG ACTTCGTGGC ACTGCAGAGC GGCGAGGCGC TGCAGAGGAA GCTCCCCTAC 
GTGGCCTTCA GCTTCCTCTA CATCCTCCTG GGGCTCACGG TCATTGGCGC CTTCCTCAAC 
CTGGTGGTCC TGCGCTTCCT CGTTGCCAGC GCCGACTGGC CCGAGCGCGC TGCCCGCACC 
CCCAGCCCGC GCCCCCCGGG GGCGCCCGAG AGCCGTGGCC TCTGGCTGCC CCGCCGCCCG 
GCCCGCTCCG TGGGCTCCGC CTCTGTCTTC TGCCACGTGC ACAAGCTGGA GAGGTGCGCC 
CGCGACAACC TGGGCTTTTC GCCCCCCTCG AGCCCGGGGG TCGTGCGTGG CGGGCAGGCT 
CCCAGGCTTG GGGCCCGGTG GAAGTCCATC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071753.2
CDS	47..1039
Translation	MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYRELERLALQAEPHRAGRQWKFPGSFYFAITVITTIEYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLNLVVLRFLVASADWPERAARTPSPRPPGAPESRGLWLPRRPARSVGSASVFCHVHKLERCARDNLGFSPPSSPGVVRGGQAPRLGARWKSI

Target ORF information:

RefSeq Version	NM_022358.4
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium two pore domain channel subfamily K member 15 (KCNK15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022358.4

ORF Insert Sequence:

ATGCGGAGGC CGAGCGTGCG CGCGGCCGGG CTGGTCCTGT GCACCCTGTG TTACCTGCTG 
GTGGGCGCTG CTGTCTTCGA CGCGCTCGAG TCCGAGGCGG AAAGCGGCCG CCAGCGACTG 
CTGGTCCAGA AGCGGGGCGC TCTCCGGAGG AAGTTCGGCT TCTCGGCCGA GGACTACCGC 
GAGCTGGAGC GCCTGGCGCT CCAGGCTGAG CCCCACCGCG CCGGCCGCCA GTGGAAGTTC 
CCCGGCTCCT TCTACTTCGC CATCACCGTC ATCACTACCA TCGAGTACGG CCACGCCGCG 
CCGGGTACGG ACTCCGGCAA GGTCTTCTGC ATGTTCTACG CGCTCCTGGG CATCCCGCTG 
ACGCTGGTCA CTTTCCAGAG CCTGGGCGAA CGGCTGAACG CGGTGGTGCG GCGCCTCCTG 
TTGGCGGCCA AGTGCTGCCT GGGCCTGCGG TGGACGTGCG TGTCCACGGA GAACCTGGTG 
GTGGCCGGGC TGCTGGCGTG TGCCGCCACC CTGGCCCTCG GGGCCGTCGC CTTCTCGCAC 
TTCGAGGGCT GGACCTTCTT CCACGCCTAC TACTACTGCT TCATCACCCT CACCACCATC 
GGCTTCGGCG ACTTCGTGGC ACTGCAGAGC GGCGAGGCGC TGCAGAGGAA GCTCCCCTAC 
GTGGCCTTCA GCTTCCTCTA CATCCTCCTG GGGCTCACGG TCATTGGCGC CTTCCTCAAC 
CTGGTGGTCC TGCGCTTCCT CGTTGCCAGC GCCGACTGGC CCGAGCGCGC TGCCCGCACC 
CCCAGCCCGC GCCCCCCGGG GGCGCCCGAG AGCCGTGGCC TCTGGCTGCC CCGCCGCCCG 
GCCCGCTCCG TGGGCTCCGC CTCTGTCTTC TGCCACGTGC ACAAGCTGGA GAGGTGCGCC 
CGCGACAACC TGGGCTTTTC GCCCCCCTCG AGCCCGGGGG TCGTGCGTGG CGGGCAGGCT 
CCCAGGCTTG GGGCCCGGTG GAAGTCCATC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
PloS one7(12)e51954(2012)
Comuzzie AG,Cole SA,Laston SL,Voruganti VS,Haack K,Gibbs RA,Butte NF

International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels.
Pharmacological reviews57(4)527-40(2005 Dec)
Goldstein SA,Bayliss DA,Kim D,Lesage F,Plant LD,Rajan S

The DNA sequence and comparative analysis of human chromosome 20.
Nature414(6866)865-71(2001 Dec 20-27)
Deloukas P,Matthews LH,Ashurst J,Burton J,Gilbert JG,Jones M,Stavrides G,Almeida JP,Babbage AK,Bagguley CL,Bailey J,Barlow KF,Bates KN,Beard LM,Beare DM,Beasley OP,Bird CP,Blakey SE,Bridgeman AM,Brown AJ,Buck D,Burrill W,Butler AP,Carder C,Carter NP,Chapman JC,Clamp M,Clark G,Clark LN,Clark SY,Clee CM,Clegg S,Cobley VE,Collier RE,Connor R,Corby NR,Coulson A,Coville GJ,Deadman R,Dhami P,Dunn M,Ellington AG,Frankland JA,Fraser A,French L,Garner P,Grafham DV,Griffiths C,Griffiths MN,Gwilliam R,Hall RE,Hammond S,Harley JL,Heath PD,Ho S,Holden JL,Howden PJ,Huckle E,Hunt AR,Hunt SE,Jekosch K,Johnson CM,Johnson D,Kay MP,Kimberley AM,King A,Knights A,Laird GK,Lawlor S,Lehvaslaiho MH,Leversha M,Lloyd C,Lloyd DM,Lovell JD,Marsh VL,Martin SL,McConnachie LJ,McLay K,McMurray AA,Milne S,Mistry D,Moore MJ,Mullikin JC,Nickerson T,Oliver K,Parker A,Patel R,Pearce TA,Peck AI,Phillimore BJ,Prathalingam SR,Plumb RW,Ramsay H,Rice CM,Ross MT,Scott CE,Sehra HK,Shownkeen R,Sims S,Skuce CD,Smith ML,Soderlund C,Steward CA,Sulston JE,Swann M,Sycamore N,Taylor R,Tee L,Thomas DW,Thorpe A,Tracey A,Tromans AC,Vaudin M,Wall M,Wallis JM,Whitehead SL,Whittaker P,Willey DL,Williams L,Williams SA,Wilming L,Wray PW,Hubbard T,Durbin RM,Bentley DR,Beck S,Rogers J

Expression pattern in brain of TASK-1, TASK-3, and a tandem pore domain K(+) channel subunit, TASK-5, associated with the central auditory nervous system.
Molecular and cellular neurosciences18(6)632-48(2001 Dec)
Karschin C,Wischmeyer E,Preisig-Müller R,Rajan S,Derst C,Grzeschik KH,Daut J,Karschin A

TASK-5, a novel member of the tandem pore K+ channel family.
Pflugers Archiv : European journal of physiology442(6)828-33(2001 Sep)
Ashmole I,Goodwin PA,Stanfield PR

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KCNK15 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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