JAM2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	JAM2
Entrez Gene ID	58494
Full Name	junctional adhesion molecule 2
Synonyms	C21orf43,CD322,JAM-B,JAMB,PRO245,VE-JAM,VEJAM
General protein information	Preferred Names junctional adhesion molecule 2 Names junctional adhesion molecule B JAM-2 JAM-IT/VE-JAM vascular endothelial junction-associated molecule
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 21 Map Location: 21q21.3
Summary	This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012].
Disorder MIM:	606870

mRNA and Protein(s)

mRNA	Protein	Name
NM_021219.3	NP_067042.1	junctional adhesion molecule B isoform 1 precursor
NM_001270408.1	NP_001257337.1	junctional adhesion molecule B isoform 3 precursor
NM_001270407.1	NP_001257336.1	junctional adhesion molecule B isoform 2 precursor
XM_024452123.1	XP_024307891.1	junctional adhesion molecule B isoform X1
XM_024452124.1	XP_024307892.1	junctional adhesion molecule B isoform X1
NM_001270408.2	NP_001257337.1	junctional adhesion molecule B isoform 3 precursor
NM_021219.4	NP_067042.1	junctional adhesion molecule B isoform 1 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Jam2	NP_001029176.1
Homo sapiens (human)	JAM2	NP_067042.1
Bos taurus (cattle)	JAM2	NP_001077205.1
Mus musculus (house mouse)	Jam2	NP_076333.3
Gallus gallus (chicken)	JAM2	NP_001006257.1
Xenopus tropicalis (tropical clawed frog)	jam2	NP_001072218.1
Pan troglodytes (chimpanzee)	JAM2	XP_001157948.1
Canis lupus familiaris (dog)	JAM2	XP_535568.1

Gene Ontology
Bibliography

Related articles in PubMed

MicroRNA-374b inhibits cervical cancer cell proliferation and induces apoptosis through the p38/ERK signaling pathway by binding to JAM-2.
Li GC, Cao XY, Li YN, Qiu YY, Li YN, Liu XJ, Sun XX
Journal of cellular physiology233(9)7379-7390(2018 09)

The role of JAM-B in cancer and cancer metastasis (Review).
Zhao H, Yu H, Martin TA, Teng X, Jiang WG
Oncology reports36(1)3-9(2016 Jul)

Effect of junctional adhesion molecule-2 expression on cell growth, invasion and migration in human colorectal cancer.
Zhao H, Yu H, Martin TA, Zhang Y, Chen G, Jiang WG
International journal of oncology48(3)929-36(2016 Mar)

Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts.
Khondoker M, Newhouse S, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Dobson R, Simmons A, ,
Journal of Alzheimer's disease : JAD45(3)851-64(2015)

Function of Jam-B/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells.
Arcangeli ML, Bardin F, Frontera V, Bidaut G, Obrados E, Adams RH, Chabannon C, Aurrand-Lions M
Stem cells (Dayton, Ohio)32(4)1043-54(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following JAM2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the JAM2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03648	NM_001270407.1 Latest version!	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu03650	NM_001270408.2 Latest version!	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu105204	XM_024452124.1 Latest version!	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu105204	XM_024452123.1 Latest version!	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu56087	NM_021219.4 Latest version!	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
View Old Accession Versions >>
OHu03650	NM_001270408.1	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu56087	NM_021219.3	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

JAM2 ( NM_021219.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_067042.1 Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu56087
Clone ID Related Accession (Same CDS sequence)	NM_021219.3 , NM_021219.4
Accession Version	NM_021219.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	junctional adhesion molecule B isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM921497.1, AY077698.1, AK294769.1, CX870550.1, AK056079.1, BG540412.1 and AI742752.1. On Jul 4, 2012 this sequence version replaced NM_021219.2. Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.160828.1, SRR1803614.52505.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGGA GGAGCCGCCA CCGCCTCCTC CTGCTGCTGC TGCGCTACCT GGTGGTCGCC 
CTGGGCTATC ATAAGGCCTA TGGGTTTTCT GCCCCAAAAG ACCAACAAGT AGTCACAGCA 
GTAGAGTACC AAGAGGCTAT TTTAGCCTGC AAAACCCCAA AGAAGACTGT TTCCTCCAGA 
TTAGAGTGGA AGAAACTGGG TCGGAGTGTC TCCTTTGTCT ACTATCAACA GACTCTTCAA 
GGTGATTTTA AAAATCGAGC TGAGATGATA GATTTCAATA TCCGGATCAA AAATGTGACA 
AGAAGTGATG CGGGGAAATA TCGTTGTGAA GTTAGTGCCC CATCTGAGCA AGGCCAAAAC 
CTGGAAGAGG ATACAGTCAC TCTGGAAGTA TTAGTGGCTC CAGCAGTTCC ATCATGTGAA 
GTACCCTCTT CTGCTCTGAG TGGAACTGTG GTAGAGCTAC GATGTCAAGA CAAAGAAGGG 
AATCCAGCTC CTGAATACAC ATGGTTTAAG GATGGCATCC GTTTGCTAGA AAATCCCAGA 
CTTGGCTCCC AAAGCACCAA CAGCTCATAC ACAATGAATA CAAAAACTGG AACTCTGCAA 
TTTAATACTG TTTCCAAACT GGACACTGGA GAATATTCCT GTGAAGCCCG CAATTCTGTT 
GGATATCGCA GGTGTCCTGG GAAACGAATG CAAGTAGATG ATCTCAACAT AAGTGGCATC 
ATAGCAGCCG TAGTAGTTGT GGCCTTAGTG ATTTCCGTTT GTGGCCTTGG TGTATGCTAT 
GCTCAGAGGA AAGGCTACTT TTCAAAAGAA ACCTCCTTCC AGAAGAGTAA TTCTTCATCT 
AAAGCCACGA CAATGAGTGA AAATGATTTC AAGCACACAA AATCCTTTAT AATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067042.1
CDS	541..1437
Translation	MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII

Target ORF information:

RefSeq Version	NM_021219.3
Organism	Homo sapiens(human)
Definition	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021219.3

ORF Insert Sequence:

ATGGCGAGGA GGAGCCGCCA CCGCCTCCTC CTGCTGCTGC TGCGCTACCT GGTGGTCGCC 
CTGGGCTATC ATAAGGCCTA TGGGTTTTCT GCCCCAAAAG ACCAACAAGT AGTCACAGCA 
GTAGAGTACC AAGAGGCTAT TTTAGCCTGC AAAACCCCAA AGAAGACTGT TTCCTCCAGA 
TTAGAGTGGA AGAAACTGGG TCGGAGTGTC TCCTTTGTCT ACTATCAACA GACTCTTCAA 
GGTGATTTTA AAAATCGAGC TGAGATGATA GATTTCAATA TCCGGATCAA AAATGTGACA 
AGAAGTGATG CGGGGAAATA TCGTTGTGAA GTTAGTGCCC CATCTGAGCA AGGCCAAAAC 
CTGGAAGAGG ATACAGTCAC TCTGGAAGTA TTAGTGGCTC CAGCAGTTCC ATCATGTGAA 
GTACCCTCTT CTGCTCTGAG TGGAACTGTG GTAGAGCTAC GATGTCAAGA CAAAGAAGGG 
AATCCAGCTC CTGAATACAC ATGGTTTAAG GATGGCATCC GTTTGCTAGA AAATCCCAGA 
CTTGGCTCCC AAAGCACCAA CAGCTCATAC ACAATGAATA CAAAAACTGG AACTCTGCAA 
TTTAATACTG TTTCCAAACT GGACACTGGA GAATATTCCT GTGAAGCCCG CAATTCTGTT 
GGATATCGCA GGTGTCCTGG GAAACGAATG CAAGTAGATG ATCTCAACAT AAGTGGCATC 
ATAGCAGCCG TAGTAGTTGT GGCCTTAGTG ATTTCCGTTT GTGGCCTTGG TGTATGCTAT 
GCTCAGAGGA AAGGCTACTT TTCAAAAGAA ACCTCCTTCC AGAAGAGTAA TTCTTCATCT 
AAAGCCACGA CAATGAGTGA AAATGATTTC AAGCACACAA AATCCTTTAT AATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JAM2 ( NM_001270407.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001257336.1 Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03648
Clone ID Related Accession (Same CDS sequence)	NM_001270407.1
Accession Version	NM_001270407.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570377600000
Organism	Homo sapiens(human)
Product	junctional adhesion molecule B isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM921497.1, AK294769.1, CX870550.1, AK056079.1, BG540412.1 and AI742752.1. Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1, which results in a shorter isoform (2) missing an internal protein segment compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294769.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGGA GGAGCCGCCA CCGCCTCCTC CTGCTGCTGC TGCGCTACCT GGTGGTCGCC 
CTGGGCTATC ATAAGGCCTA TGGGTTTTCT GCCCCAAAAG ACCAACAAGT AGTCACAGCA 
GTAGAGTACC AAGGTGATTT TAAAAATCGA GCTGAGATGA TAGATTTCAA TATCCGGATC 
AAAAATGTGA CAAGAAGTGA TGCGGGGAAA TATCGTTGTG AAGTTAGTGC CCCATCTGAG 
CAAGGCCAAA ACCTGGAAGA GGATACAGTC ACTCTGGAAG TATTAGTGGC TCCAGCAGTT 
CCATCATGTG AAGTACCCTC TTCTGCTCTG AGTGGAACTG TGGTAGAGCT ACGATGTCAA 
GACAAAGAAG GGAATCCAGC TCCTGAATAC ACATGGTTTA AGGATGGCAT CCGTTTGCTA 
GAAAATCCCA GACTTGGCTC CCAAAGCACC AACAGCTCAT ACACAATGAA TACAAAAACT 
GGAACTCTGC AATTTAATAC TGTTTCCAAA CTGGACACTG GAGAATATTC CTGTGAAGCC 
CGCAATTCTG TTGGATATCG CAGGTGTCCT GGGAAACGAA TGCAAGTAGA TGATCTCAAC 
ATAAGTGGCA TCATAGCAGC CGTAGTAGTT GTGGCCTTAG TGATTTCCGT TTGTGGCCTT 
GGTGTATGCT ATGCTCAGAG GAAAGGCTAC TTTTCAAAAG AAACCTCCTT CCAGAAGAGT 
AATTCTTCAT CTAAAGCCAC GACAATGAGT GAAAATGATT TCAAGCACAC AAAATCCTTT 
ATAATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257336.1
CDS	541..1329
Translation	MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII

Target ORF information:

RefSeq Version	NM_001270407.1
Organism	Homo sapiens(human)
Definition	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270407.1

ORF Insert Sequence:

ATGGCGAGGA GGAGCCGCCA CCGCCTCCTC CTGCTGCTGC TGCGCTACCT GGTGGTCGCC 
CTGGGCTATC ATAAGGCCTA TGGGTTTTCT GCCCCAAAAG ACCAACAAGT AGTCACAGCA 
GTAGAGTACC AAGGTGATTT TAAAAATCGA GCTGAGATGA TAGATTTCAA TATCCGGATC 
AAAAATGTGA CAAGAAGTGA TGCGGGGAAA TATCGTTGTG AAGTTAGTGC CCCATCTGAG 
CAAGGCCAAA ACCTGGAAGA GGATACAGTC ACTCTGGAAG TATTAGTGGC TCCAGCAGTT 
CCATCATGTG AAGTACCCTC TTCTGCTCTG AGTGGAACTG TGGTAGAGCT ACGATGTCAA 
GACAAAGAAG GGAATCCAGC TCCTGAATAC ACATGGTTTA AGGATGGCAT CCGTTTGCTA 
GAAAATCCCA GACTTGGCTC CCAAAGCACC AACAGCTCAT ACACAATGAA TACAAAAACT 
GGAACTCTGC AATTTAATAC TGTTTCCAAA CTGGACACTG GAGAATATTC CTGTGAAGCC 
CGCAATTCTG TTGGATATCG CAGGTGTCCT GGGAAACGAA TGCAAGTAGA TGATCTCAAC 
ATAAGTGGCA TCATAGCAGC CGTAGTAGTT GTGGCCTTAG TGATTTCCGT TTGTGGCCTT 
GGTGTATGCT ATGCTCAGAG GAAAGGCTAC TTTTCAAAAG AAACCTCCTT CCAGAAGAGT 
AATTCTTCAT CTAAAGCCAC GACAATGAGT GAAAATGATT TCAAGCACAC AAAATCCTTT 
ATAATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JAM2 ( NM_001270408.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001257337.1 Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu03650
Clone ID Related Accession (Same CDS sequence)	NM_001270408.1 , NM_001270408.2
Accession Version	NM_001270408.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550764800000
Organism	Homo sapiens(human)
Product	junctional adhesion molecule B isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM921497.1 and AY358361.1. Transcript Variant: This variant (3) contains an alternate 3' terminal exon compared to variant 1, which results in a frame-shift, and a longer isoform (3) with a distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358361.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGGA GGAGCCGCCA CCGCCTCCTC CTGCTGCTGC TGCGCTACCT GGTGGTCGCC 
CTGGGCTATC ATAAGGCCTA TGGGTTTTCT GCCCCAAAAG ACCAACAAGT AGTCACAGCA 
GTAGAGTACC AAGAGGCTAT TTTAGCCTGC AAAACCCCAA AGAAGACTGT TTCCTCCAGA 
TTAGAGTGGA AGAAACTGGG TCGGAGTGTC TCCTTTGTCT ACTATCAACA GACTCTTCAA 
GGTGATTTTA AAAATCGAGC TGAGATGATA GATTTCAATA TCCGGATCAA AAATGTGACA 
AGAAGTGATG CGGGGAAATA TCGTTGTGAA GTTAGTGCCC CATCTGAGCA AGGCCAAAAC 
CTGGAAGAGG ATACAGTCAC TCTGGAAGTA TTAGTGGCTC CAGCAGTTCC ATCATGTGAA 
GTACCCTCTT CTGCTCTGAG TGGAACTGTG GTAGAGCTAC GATGTCAAGA CAAAGAAGGG 
AATCCAGCTC CTGAATACAC ATGGTTTAAG GATGGCATCC GTTTGCTAGA AAATCCCAGA 
CTTGGCTCCC AAAGCACCAA CAGCTCATAC ACAATGAATA CAAAAACTGG AACTCTGCAA 
TTTAATACTG TTTCCAAACT GGACACTGGA GAATATTCCT GTGAAGCCCG CAATTCTGTT 
GGATATCGCA GGTGTCCTGG GAAACGAATG CAAGTAGATG ATCTCAACAT AAGTGGCATC 
ATAGCAGCCG TAGTAGTTGT GGCCTTAGTG ATTTCCGTTT GTGGCCTTGG TGTATGCTAT 
GCTCAGAGGA AAGGCTACTT TTCAAAAGAA ACCTCCTTCC AGAAGAGTAA TTCTTCATCT 
AAAGCCACGA CAATGAGTGA AAATGTGCAG TGGCTCACGC CTGTAATCCC AGCACTTTGG 
AAGGCCGCGG CGGGCGGATC ACGAGGTCAG GAGTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257337.1
CDS	541..1479
Translation	MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENVQWLTPVIPALWKAAAGGSRGQEF

Target ORF information:

RefSeq Version	NM_001270408.1
Organism	Homo sapiens(human)
Definition	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270408.1

ORF Insert Sequence:

ATGGCGAGGA GGAGCCGCCA CCGCCTCCTC CTGCTGCTGC TGCGCTACCT GGTGGTCGCC 
CTGGGCTATC ATAAGGCCTA TGGGTTTTCT GCCCCAAAAG ACCAACAAGT AGTCACAGCA 
GTAGAGTACC AAGAGGCTAT TTTAGCCTGC AAAACCCCAA AGAAGACTGT TTCCTCCAGA 
TTAGAGTGGA AGAAACTGGG TCGGAGTGTC TCCTTTGTCT ACTATCAACA GACTCTTCAA 
GGTGATTTTA AAAATCGAGC TGAGATGATA GATTTCAATA TCCGGATCAA AAATGTGACA 
AGAAGTGATG CGGGGAAATA TCGTTGTGAA GTTAGTGCCC CATCTGAGCA AGGCCAAAAC 
CTGGAAGAGG ATACAGTCAC TCTGGAAGTA TTAGTGGCTC CAGCAGTTCC ATCATGTGAA 
GTACCCTCTT CTGCTCTGAG TGGAACTGTG GTAGAGCTAC GATGTCAAGA CAAAGAAGGG 
AATCCAGCTC CTGAATACAC ATGGTTTAAG GATGGCATCC GTTTGCTAGA AAATCCCAGA 
CTTGGCTCCC AAAGCACCAA CAGCTCATAC ACAATGAATA CAAAAACTGG AACTCTGCAA 
TTTAATACTG TTTCCAAACT GGACACTGGA GAATATTCCT GTGAAGCCCG CAATTCTGTT 
GGATATCGCA GGTGTCCTGG GAAACGAATG CAAGTAGATG ATCTCAACAT AAGTGGCATC 
ATAGCAGCCG TAGTAGTTGT GGCCTTAGTG ATTTCCGTTT GTGGCCTTGG TGTATGCTAT 
GCTCAGAGGA AAGGCTACTT TTCAAAAGAA ACCTCCTTCC AGAAGAGTAA TTCTTCATCT 
AAAGCCACGA CAATGAGTGA AAATGTGCAG TGGCTCACGC CTGTAATCCC AGCACTTTGG 
AAGGCCGCGG CGGGCGGATC ACGAGGTCAG GAGTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JAM2 ( NM_001270408.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001257337.1 Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu03650
Clone ID Related Accession (Same CDS sequence)	NM_001270408.1 , NM_001270408.2
Accession Version	NM_001270408.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570377600000
Organism	Homo sapiens(human)
Product	junctional adhesion molecule B isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000223.1, BM921497.1, AY358361.1 and AP000226.2. On May 31, 2019 this sequence version replaced NM_001270408.1. Transcript Variant: This variant (3) contains an alternate 3' terminal exon compared to variant 1, which results in a frame-shift, and a longer isoform (3) with a distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358361.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGGA GGAGCCGCCA CCGCCTCCTC CTGCTGCTGC TGCGCTACCT GGTGGTCGCC 
CTGGGCTATC ATAAGGCCTA TGGGTTTTCT GCCCCAAAAG ACCAACAAGT AGTCACAGCA 
GTAGAGTACC AAGAGGCTAT TTTAGCCTGC AAAACCCCAA AGAAGACTGT TTCCTCCAGA 
TTAGAGTGGA AGAAACTGGG TCGGAGTGTC TCCTTTGTCT ACTATCAACA GACTCTTCAA 
GGTGATTTTA AAAATCGAGC TGAGATGATA GATTTCAATA TCCGGATCAA AAATGTGACA 
AGAAGTGATG CGGGGAAATA TCGTTGTGAA GTTAGTGCCC CATCTGAGCA AGGCCAAAAC 
CTGGAAGAGG ATACAGTCAC TCTGGAAGTA TTAGTGGCTC CAGCAGTTCC ATCATGTGAA 
GTACCCTCTT CTGCTCTGAG TGGAACTGTG GTAGAGCTAC GATGTCAAGA CAAAGAAGGG 
AATCCAGCTC CTGAATACAC ATGGTTTAAG GATGGCATCC GTTTGCTAGA AAATCCCAGA 
CTTGGCTCCC AAAGCACCAA CAGCTCATAC ACAATGAATA CAAAAACTGG AACTCTGCAA 
TTTAATACTG TTTCCAAACT GGACACTGGA GAATATTCCT GTGAAGCCCG CAATTCTGTT 
GGATATCGCA GGTGTCCTGG GAAACGAATG CAAGTAGATG ATCTCAACAT AAGTGGCATC 
ATAGCAGCCG TAGTAGTTGT GGCCTTAGTG ATTTCCGTTT GTGGCCTTGG TGTATGCTAT 
GCTCAGAGGA AAGGCTACTT TTCAAAAGAA ACCTCCTTCC AGAAGAGTAA TTCTTCATCT 
AAAGCCACGA CAATGAGTGA AAATGTGCAG TGGCTCACGC CTGTAATCCC AGCACTTTGG 
AAGGCCGCGG CGGGCGGATC ACGAGGTCAG GAGTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257337.1
CDS	565..1503
Translation	MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENVQWLTPVIPALWKAAAGGSRGQEF

Target ORF information:

RefSeq Version	NM_001270408.2
Organism	Homo sapiens(human)
Definition	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270408.2

ORF Insert Sequence:

ATGGCGAGGA GGAGCCGCCA CCGCCTCCTC CTGCTGCTGC TGCGCTACCT GGTGGTCGCC 
CTGGGCTATC ATAAGGCCTA TGGGTTTTCT GCCCCAAAAG ACCAACAAGT AGTCACAGCA 
GTAGAGTACC AAGAGGCTAT TTTAGCCTGC AAAACCCCAA AGAAGACTGT TTCCTCCAGA 
TTAGAGTGGA AGAAACTGGG TCGGAGTGTC TCCTTTGTCT ACTATCAACA GACTCTTCAA 
GGTGATTTTA AAAATCGAGC TGAGATGATA GATTTCAATA TCCGGATCAA AAATGTGACA 
AGAAGTGATG CGGGGAAATA TCGTTGTGAA GTTAGTGCCC CATCTGAGCA AGGCCAAAAC 
CTGGAAGAGG ATACAGTCAC TCTGGAAGTA TTAGTGGCTC CAGCAGTTCC ATCATGTGAA 
GTACCCTCTT CTGCTCTGAG TGGAACTGTG GTAGAGCTAC GATGTCAAGA CAAAGAAGGG 
AATCCAGCTC CTGAATACAC ATGGTTTAAG GATGGCATCC GTTTGCTAGA AAATCCCAGA 
CTTGGCTCCC AAAGCACCAA CAGCTCATAC ACAATGAATA CAAAAACTGG AACTCTGCAA 
TTTAATACTG TTTCCAAACT GGACACTGGA GAATATTCCT GTGAAGCCCG CAATTCTGTT 
GGATATCGCA GGTGTCCTGG GAAACGAATG CAAGTAGATG ATCTCAACAT AAGTGGCATC 
ATAGCAGCCG TAGTAGTTGT GGCCTTAGTG ATTTCCGTTT GTGGCCTTGG TGTATGCTAT 
GCTCAGAGGA AAGGCTACTT TTCAAAAGAA ACCTCCTTCC AGAAGAGTAA TTCTTCATCT 
AAAGCCACGA CAATGAGTGA AAATGTGCAG TGGCTCACGC CTGTAATCCC AGCACTTTGG 
AAGGCCGCGG CGGGCGGATC ACGAGGTCAG GAGTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JAM2 ( XM_024452123.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307891.1 Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu105204
Clone ID Related Accession (Same CDS sequence)	XM_024452123.1 , XM_024452124.1
Accession Version	XM_024452123.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	junctional adhesion molecule B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATAGATT TCAATATCCG GATCAAAAAT GTGACAAGAA GTGATGCGGG GAAATATCGT 
TGTGAAGTTA GTGCCCCATC TGAGCAAGGC CAAAACCTGG AAGAGGATAC AGTCACTCTG 
GAAGTATTAG TGGCTCCAGC AGTTCCATCA TGTGAAGTAC CCTCTTCTGC TCTGAGTGGA 
ACTGTGGTAG AGCTACGATG TCAAGACAAA GAAGGGAATC CAGCTCCTGA ATACACATGG 
TTTAAGGATG GCATCCGTTT GCTAGAAAAT CCCAGACTTG GCTCCCAAAG CACCAACAGC 
TCATACACAA TGAATACAAA AACTGGAACT CTGCAATTTA ATACTGTTTC CAAACTGGAC 
ACTGGAGAAT ATTCCTGTGA AGCCCGCAAT TCTGTTGGAT ATCGCAGGTG TCCTGGGAAA 
CGAATGCAAG TAGATGATCT CAACATAAGT GGCATCATAG CAGCCGTAGT AGTTGTGGCC 
TTAGTGATTT CCGTTTGTGG CCTTGGTGTA TGCTATGCTC AGAGGAAAGG CTACTTTTCA 
AAAGAAACCT CCTTCCAGAA GAGTAATTCT TCATCTAAAG CCACGACAAT GAGTGAAAAT 
GATTTCAAGC ACACAAAATC CTTTATAATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307891.1
CDS	557..1189
Translation	MIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII

Target ORF information:

RefSeq Version	XM_024452123.1
Organism	Homo sapiens(human)
Definition	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452123.1

ORF Insert Sequence:

ATGATAGATT TCAATATCCG GATCAAAAAT GTGACAAGAA GTGATGCGGG GAAATATCGT 
TGTGAAGTTA GTGCCCCATC TGAGCAAGGC CAAAACCTGG AAGAGGATAC AGTCACTCTG 
GAAGTATTAG TGGCTCCAGC AGTTCCATCA TGTGAAGTAC CCTCTTCTGC TCTGAGTGGA 
ACTGTGGTAG AGCTACGATG TCAAGACAAA GAAGGGAATC CAGCTCCTGA ATACACATGG 
TTTAAGGATG GCATCCGTTT GCTAGAAAAT CCCAGACTTG GCTCCCAAAG CACCAACAGC 
TCATACACAA TGAATACAAA AACTGGAACT CTGCAATTTA ATACTGTTTC CAAACTGGAC 
ACTGGAGAAT ATTCCTGTGA AGCCCGCAAT TCTGTTGGAT ATCGCAGGTG TCCTGGGAAA 
CGAATGCAAG TAGATGATCT CAACATAAGT GGCATCATAG CAGCCGTAGT AGTTGTGGCC 
TTAGTGATTT CCGTTTGTGG CCTTGGTGTA TGCTATGCTC AGAGGAAAGG CTACTTTTCA 
AAAGAAACCT CCTTCCAGAA GAGTAATTCT TCATCTAAAG CCACGACAAT GAGTGAAAAT 
GATTTCAAGC ACACAAAATC CTTTATAATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JAM2 ( XM_024452124.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307892.1 Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu105204
Clone ID Related Accession (Same CDS sequence)	XM_024452123.1 , XM_024452124.1
Accession Version	XM_024452124.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	junctional adhesion molecule B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATAGATT TCAATATCCG GATCAAAAAT GTGACAAGAA GTGATGCGGG GAAATATCGT 
TGTGAAGTTA GTGCCCCATC TGAGCAAGGC CAAAACCTGG AAGAGGATAC AGTCACTCTG 
GAAGTATTAG TGGCTCCAGC AGTTCCATCA TGTGAAGTAC CCTCTTCTGC TCTGAGTGGA 
ACTGTGGTAG AGCTACGATG TCAAGACAAA GAAGGGAATC CAGCTCCTGA ATACACATGG 
TTTAAGGATG GCATCCGTTT GCTAGAAAAT CCCAGACTTG GCTCCCAAAG CACCAACAGC 
TCATACACAA TGAATACAAA AACTGGAACT CTGCAATTTA ATACTGTTTC CAAACTGGAC 
ACTGGAGAAT ATTCCTGTGA AGCCCGCAAT TCTGTTGGAT ATCGCAGGTG TCCTGGGAAA 
CGAATGCAAG TAGATGATCT CAACATAAGT GGCATCATAG CAGCCGTAGT AGTTGTGGCC 
TTAGTGATTT CCGTTTGTGG CCTTGGTGTA TGCTATGCTC AGAGGAAAGG CTACTTTTCA 
AAAGAAACCT CCTTCCAGAA GAGTAATTCT TCATCTAAAG CCACGACAAT GAGTGAAAAT 
GATTTCAAGC ACACAAAATC CTTTATAATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307892.1
CDS	579..1211
Translation	MIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII

Target ORF information:

RefSeq Version	XM_024452124.1
Organism	Homo sapiens(human)
Definition	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452124.1

ORF Insert Sequence:

ATGATAGATT TCAATATCCG GATCAAAAAT GTGACAAGAA GTGATGCGGG GAAATATCGT 
TGTGAAGTTA GTGCCCCATC TGAGCAAGGC CAAAACCTGG AAGAGGATAC AGTCACTCTG 
GAAGTATTAG TGGCTCCAGC AGTTCCATCA TGTGAAGTAC CCTCTTCTGC TCTGAGTGGA 
ACTGTGGTAG AGCTACGATG TCAAGACAAA GAAGGGAATC CAGCTCCTGA ATACACATGG 
TTTAAGGATG GCATCCGTTT GCTAGAAAAT CCCAGACTTG GCTCCCAAAG CACCAACAGC 
TCATACACAA TGAATACAAA AACTGGAACT CTGCAATTTA ATACTGTTTC CAAACTGGAC 
ACTGGAGAAT ATTCCTGTGA AGCCCGCAAT TCTGTTGGAT ATCGCAGGTG TCCTGGGAAA 
CGAATGCAAG TAGATGATCT CAACATAAGT GGCATCATAG CAGCCGTAGT AGTTGTGGCC 
TTAGTGATTT CCGTTTGTGG CCTTGGTGTA TGCTATGCTC AGAGGAAAGG CTACTTTTCA 
AAAGAAACCT CCTTCCAGAA GAGTAATTCT TCATCTAAAG CCACGACAAT GAGTGAAAAT 
GATTTCAAGC ACACAAAATC CTTTATAATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JAM2 ( NM_021219.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_067042.1 Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu56087
Clone ID Related Accession (Same CDS sequence)	NM_021219.3 , NM_021219.4
Accession Version	NM_021219.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570377600000
Organism	Homo sapiens(human)
Product	junctional adhesion molecule B isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000223.1, BM921497.1, AY077698.1, AK294769.1, CX870550.1, AK056079.1, BG540412.1 and AI742752.1. On Nov 22, 2018 this sequence version replaced NM_021219.3. Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.160828.1, SRR1803614.52505.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000480456.6/ ENSP00000420419.1 RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGAGGA GGAGCCGCCA CCGCCTCCTC CTGCTGCTGC TGCGCTACCT GGTGGTCGCC 
CTGGGCTATC ATAAGGCCTA TGGGTTTTCT GCCCCAAAAG ACCAACAAGT AGTCACAGCA 
GTAGAGTACC AAGAGGCTAT TTTAGCCTGC AAAACCCCAA AGAAGACTGT TTCCTCCAGA 
TTAGAGTGGA AGAAACTGGG TCGGAGTGTC TCCTTTGTCT ACTATCAACA GACTCTTCAA 
GGTGATTTTA AAAATCGAGC TGAGATGATA GATTTCAATA TCCGGATCAA AAATGTGACA 
AGAAGTGATG CGGGGAAATA TCGTTGTGAA GTTAGTGCCC CATCTGAGCA AGGCCAAAAC 
CTGGAAGAGG ATACAGTCAC TCTGGAAGTA TTAGTGGCTC CAGCAGTTCC ATCATGTGAA 
GTACCCTCTT CTGCTCTGAG TGGAACTGTG GTAGAGCTAC GATGTCAAGA CAAAGAAGGG 
AATCCAGCTC CTGAATACAC ATGGTTTAAG GATGGCATCC GTTTGCTAGA AAATCCCAGA 
CTTGGCTCCC AAAGCACCAA CAGCTCATAC ACAATGAATA CAAAAACTGG AACTCTGCAA 
TTTAATACTG TTTCCAAACT GGACACTGGA GAATATTCCT GTGAAGCCCG CAATTCTGTT 
GGATATCGCA GGTGTCCTGG GAAACGAATG CAAGTAGATG ATCTCAACAT AAGTGGCATC 
ATAGCAGCCG TAGTAGTTGT GGCCTTAGTG ATTTCCGTTT GTGGCCTTGG TGTATGCTAT 
GCTCAGAGGA AAGGCTACTT TTCAAAAGAA ACCTCCTTCC AGAAGAGTAA TTCTTCATCT 
AAAGCCACGA CAATGAGTGA AAATGATTTC AAGCACACAA AATCCTTTAT AATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067042.1
CDS	565..1461
Translation	MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII

Target ORF information:

RefSeq Version	NM_021219.4
Organism	Homo sapiens(human)
Definition	Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021219.4

ORF Insert Sequence:

ATGGCGAGGA GGAGCCGCCA CCGCCTCCTC CTGCTGCTGC TGCGCTACCT GGTGGTCGCC 
CTGGGCTATC ATAAGGCCTA TGGGTTTTCT GCCCCAAAAG ACCAACAAGT AGTCACAGCA 
GTAGAGTACC AAGAGGCTAT TTTAGCCTGC AAAACCCCAA AGAAGACTGT TTCCTCCAGA 
TTAGAGTGGA AGAAACTGGG TCGGAGTGTC TCCTTTGTCT ACTATCAACA GACTCTTCAA 
GGTGATTTTA AAAATCGAGC TGAGATGATA GATTTCAATA TCCGGATCAA AAATGTGACA 
AGAAGTGATG CGGGGAAATA TCGTTGTGAA GTTAGTGCCC CATCTGAGCA AGGCCAAAAC 
CTGGAAGAGG ATACAGTCAC TCTGGAAGTA TTAGTGGCTC CAGCAGTTCC ATCATGTGAA 
GTACCCTCTT CTGCTCTGAG TGGAACTGTG GTAGAGCTAC GATGTCAAGA CAAAGAAGGG 
AATCCAGCTC CTGAATACAC ATGGTTTAAG GATGGCATCC GTTTGCTAGA AAATCCCAGA 
CTTGGCTCCC AAAGCACCAA CAGCTCATAC ACAATGAATA CAAAAACTGG AACTCTGCAA 
TTTAATACTG TTTCCAAACT GGACACTGGA GAATATTCCT GTGAAGCCCG CAATTCTGTT 
GGATATCGCA GGTGTCCTGG GAAACGAATG CAAGTAGATG ATCTCAACAT AAGTGGCATC 
ATAGCAGCCG TAGTAGTTGT GGCCTTAGTG ATTTCCGTTT GTGGCCTTGG TGTATGCTAT 
GCTCAGAGGA AAGGCTACTT TTCAAAAGAA ACCTCCTTCC AGAAGAGTAA TTCTTCATCT 
AAAGCCACGA CAATGAGTGA AAATGATTTC AAGCACACAA AATCCTTTAT AATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MicroRNA-374b inhibits cervical cancer cell proliferation and induces apoptosis through the p38/ERK signaling pathway by binding to JAM-2.
Journal of cellular physiology233(9)7379-7390(2018 09)
Li GC,Cao XY,Li YN,Qiu YY,Li YN,Liu XJ,Sun XX

The role of JAM-B in cancer and cancer metastasis (Review).
Oncology reports36(1)3-9(2016 Jul)
Zhao H,Yu H,Martin TA,Teng X,Jiang WG

Effect of junctional adhesion molecule-2 expression on cell growth, invasion and migration in human colorectal cancer.
International journal of oncology48(3)929-36(2016 Mar)
Zhao H,Yu H,Martin TA,Zhang Y,Chen G,Jiang WG

Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts.
Journal of Alzheimer's disease : JAD45(3)851-64(2015)
Khondoker M,Newhouse S,Westman E,Muehlboeck JS,Mecocci P,Vellas B,Tsolaki M,Kłoszewska I,Soininen H,Lovestone S,Dobson R,Simmons A,,

Function of Jam-B/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells.
Stem cells (Dayton, Ohio)32(4)1043-54(2014 Apr)
Arcangeli ML,Bardin F,Frontera V,Bidaut G,Obrados E,Adams RH,Chabannon C,Aurrand-Lions M

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JAM2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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