| Gene Symbol | DPM3 |
| Entrez Gene ID | 54344 |
| Full Name | dolichyl-phosphate mannosyltransferase subunit 3 |
| Synonyms | CDG1O |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex. [provided by RefSeq, Jul 2008]. |
| Disorder MIM: | |
| Disorder Html: | Congenital disorder of glycosylation, type Io, 612937 (3) |
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