PHAX cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PHAX
Entrez Gene ID	51808
Full Name	phosphorylated adaptor for RNA export
Synonyms	RNUXA
General protein information	Preferred Names phosphorylated adaptor for RNA export Names phosphorylated adapter RNA export protein RNA U small nuclear RNA export adapter protein RNA U, small nuclear RNA export adapter (phosphorylation regulated) RNA U, small nuclear RNA export adaptor (phosphorylation regulated)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q23.2
Disorder MIM:	604924

mRNA and Protein(s)

mRNA	Protein	Name
NM_032177.3	NP_115553.2	phosphorylated adapter RNA export protein
NM_032177.4	NP_115553.2	phosphorylated adapter RNA export protein

Pathways from BioSystems

Homologies

Homo sapiens (human)	PHAX	NP_115553.2
Pan troglodytes (chimpanzee)	PHAX	XP_517905.3
Rattus norvegicus (Norway rat)	Phax	NP_775156.2
Danio rerio (zebrafish)	phax	NP_001003995.1
Bos taurus (cattle)	PHAX	NP_001160034.1
Canis lupus familiaris (dog)	PHAX	XP_851359.1
Mus musculus (house mouse)	Phax	NP_064380.3
Xenopus tropicalis (tropical clawed frog)	phax	XP_002931759.1
Macaca mulatta (Rhesus monkey)	PHAX	XP_001096578.1
Gallus gallus (chicken)	PHAX	NP_001006575.1

Gene Ontology
Bibliography

Related articles in PubMed

mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3.
Gebhardt A, Habjan M, Benda C, Meiler A, Haas DA, Hein MY, Mann A, Mann M, Habermann B, Pichlmair A
Nature communications68192(2015 Sep)

Structure and RNA recognition by the snRNA and snoRNA transport factor PHAX.
Mourão A, Varrot A, Mackereth CD, Cusack S, Sattler M
RNA (New York, N.Y.)16(6)1205-16(2010 Jun)

Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies.
Lemm I, Girard C, Kuhn AN, Watkins NJ, Schneider M, Bordonné R, Lührmann R
Molecular biology of the cell17(7)3221-31(2006 Jul)

PHAX and CRM1 are required sequentially to transport U3 snoRNA to nucleoli.
Boulon S, Verheggen C, Jady BE, Girard C, Pescia C, Paul C, Ospina JK, Kiss T, Matera AG, Bordonné R, Bertrand E
Molecular cell16(5)777-87(2004 Dec)

Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex.
Watkins NJ, Lemm I, Ingelfinger D, Schneider C, Hossbach M, Urlaub H, Lührmann R
Molecular cell16(5)789-98(2004 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PHAX gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PHAX cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00907	NM_032177.4 Latest version!	Homo sapiens phosphorylated adaptor for RNA export (PHAX), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
View Old Accession Versions >>
OHu00907	NM_032177.3	Homo sapiens phosphorylated adaptor for RNA export (PHAX), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PHAX ( NM_032177.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_115553.2 Homo sapiens phosphorylated adaptor for RNA export (PHAX), mRNA.

Price & Availability↑

CloneID	OHu00907
Clone ID Related Accession (Same CDS sequence)	NM_032177.3 , NM_032177.4
Accession Version	NM_032177.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1185bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	phosphorylated adapter RNA export protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK023255.1, BC021161.2 and AC099513.3. On Jul 27, 2010 this sequence version replaced NM_032177.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.233929.1, SRR1803614.34429.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCGTTGG AGGTCGGCGA TATGGAAGAT GGGCAGCTTT CCGACTCGGA TTCCGACATG 
ACGGTCGCAC CCAGCGACAG GCCGCTGCAA TTGCCAAAAG TGCTAGGTGG CGACAGTGCT 
ATGAGGGCCT TCCAGAACAC GGCAACTGCA TGTGCACCAG TATCACATTA TCGAGCTGTT 
GAAAGTGTGG ATTCAAGTGA AGAAAGTTTT TCTGATTCAG ATGATGATAG CTGTCTTTGG 
AAACGCAAAC GACAGAAATG TTTTAACCCT CCTCCCAAAC CAGAGCCTTT TCAGTTTGGC 
CAGAGCAGTC AGAAACCACC TGTTGCTGGA GGAAAGAAGA TTAACAACAT ATGGGGTGCT 
GTGCTGCAGG AACAGAATCA AGATGCAGTG GCCACTGAAC TTGGTATCTT GGGAATGGAG 
GGCACTATTG ACAGAAGCAG ACAATCCGAG ACCTACAATT ATTTGCTTGC CAAGAAACTT 
AGGAAGGAAT CTCAAGAGCA TACAAAAGAT CTAGACAAGG AACTAGATGA ATATATGCAT 
GGTGGCAAAA AAATGGGATC AAAGGAAGAG GAAAATGGGC AAGGTCATCT CAAAAGGAAA 
CGACCTGTCA AAGACAGGCT AGGGAACAGA CCAGAAATGA ACTATAAAGG TCGATACGAG 
ATCACAGCGG AAGATTCTCA AGAGAAAGTG GCTGATGAAA TTTCATTCAG GTTACAGGAA 
CCAAAGAAAG ACCTGATAGC CCGAGTAGTG AGGATTATTG GTAACAAAAA GGCAATTGAA 
CTTCTGATGG AAACCGCTGA AGTTGAACAA AATGGTGGTC TCTTTATAAT GAATGGTAGT 
CGAAGAAGAA CACCAGGTGG AGTTTTTCTG AATCTCTTGA AAAACACTCC TAGTATCAGC 
GAGGAACAAA TTAAGGACAT TTTCTACATT GAAAACCAAA AGGAATATGA AAATAAAAAA 
GCTGCTAGGA AGAGGAGAAC ACAAGTGTTG GGGAAAAAGA TGAAACAAGC TATTAAAAGT 
CTAAATTTTC AAGAAGATGA TGATACATCA CGAGAAACTT TTGCAAGTGA CACGAATGAG 
GCCTTGGCCT CTCTTGATGA GTCACAGGAA GGACATGCAG AAGCCAAGTT GGAGGCAGAG 
GAAGCCATTG AAGTTGATCA TTCTCATGAT TTGGACATCT TTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115553.2
CDS	49..1233
Translation	MALEVGDMEDGQLSDSDSDMTVAPSDRPLQLPKVLGGDSAMRAFQNTATACAPVSHYRAVESVDSSEESFSDSDDDSCLWKRKRQKCFNPPPKPEPFQFGQSSQKPPVAGGKKINNIWGAVLQEQNQDAVATELGILGMEGTIDRSRQSETYNYLLAKKLRKESQEHTKDLDKELDEYMHGGKKMGSKEEENGQGHLKRKRPVKDRLGNRPEMNYKGRYEITAEDSQEKVADEISFRLQEPKKDLIARVVRIIGNKKAIELLMETAEVEQNGGLFIMNGSRRRTPGGVFLNLLKNTPSISEEQIKDIFYIENQKEYENKKAARKRRTQVLGKKMKQAIKSLNFQEDDDTSRETFASDTNEALASLDESQEGHAEAKLEAEEAIEVDHSHDLDIF

Target ORF information:

RefSeq Version	NM_032177.3
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphorylated adaptor for RNA export (PHAX), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032177.3

ORF Insert Sequence:

ATGGCGTTGG AGGTCGGCGA TATGGAAGAT GGGCAGCTTT CCGACTCGGA TTCCGACATG 
ACGGTCGCAC CCAGCGACAG GCCGCTGCAA TTGCCAAAAG TGCTAGGTGG CGACAGTGCT 
ATGAGGGCCT TCCAGAACAC GGCAACTGCA TGTGCACCAG TATCACATTA TCGAGCTGTT 
GAAAGTGTGG ATTCAAGTGA AGAAAGTTTT TCTGATTCAG ATGATGATAG CTGTCTTTGG 
AAACGCAAAC GACAGAAATG TTTTAACCCT CCTCCCAAAC CAGAGCCTTT TCAGTTTGGC 
CAGAGCAGTC AGAAACCACC TGTTGCTGGA GGAAAGAAGA TTAACAACAT ATGGGGTGCT 
GTGCTGCAGG AACAGAATCA AGATGCAGTG GCCACTGAAC TTGGTATCTT GGGAATGGAG 
GGCACTATTG ACAGAAGCAG ACAATCCGAG ACCTACAATT ATTTGCTTGC CAAGAAACTT 
AGGAAGGAAT CTCAAGAGCA TACAAAAGAT CTAGACAAGG AACTAGATGA ATATATGCAT 
GGTGGCAAAA AAATGGGATC AAAGGAAGAG GAAAATGGGC AAGGTCATCT CAAAAGGAAA 
CGACCTGTCA AAGACAGGCT AGGGAACAGA CCAGAAATGA ACTATAAAGG TCGATACGAG 
ATCACAGCGG AAGATTCTCA AGAGAAAGTG GCTGATGAAA TTTCATTCAG GTTACAGGAA 
CCAAAGAAAG ACCTGATAGC CCGAGTAGTG AGGATTATTG GTAACAAAAA GGCAATTGAA 
CTTCTGATGG AAACCGCTGA AGTTGAACAA AATGGTGGTC TCTTTATAAT GAATGGTAGT 
CGAAGAAGAA CACCAGGTGG AGTTTTTCTG AATCTCTTGA AAAACACTCC TAGTATCAGC 
GAGGAACAAA TTAAGGACAT TTTCTACATT GAAAACCAAA AGGAATATGA AAATAAAAAA 
GCTGCTAGGA AGAGGAGAAC ACAAGTGTTG GGGAAAAAGA TGAAACAAGC TATTAAAAGT 
CTAAATTTTC AAGAAGATGA TGATACATCA CGAGAAACTT TTGCAAGTGA CACGAATGAG 
GCCTTGGCCT CTCTTGATGA GTCACAGGAA GGACATGCAG AAGCCAAGTT GGAGGCAGAG 
GAAGCCATTG AAGTTGATCA TTCTCATGAT TTGGACATCT TTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PHAX ( NM_032177.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_115553.2 Homo sapiens phosphorylated adaptor for RNA export (PHAX), mRNA.

Price & Availability↑

CloneID	OHu00907
Clone ID Related Accession (Same CDS sequence)	NM_032177.3 , NM_032177.4
Accession Version	NM_032177.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1185bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573833600000
Organism	Homo sapiens(human)
Product	phosphorylated adapter RNA export protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK023255.1, BC021161.2 and AC099513.3. On Nov 22, 2018 this sequence version replaced NM_032177.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.260778.1, SRR1803612.233929.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000297540.5/ ENSP00000297540.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGTTGG AGGTCGGCGA TATGGAAGAT GGGCAGCTTT CCGACTCGGA TTCCGACATG 
ACGGTCGCAC CCAGCGACAG GCCGCTGCAA TTGCCAAAAG TGCTAGGTGG CGACAGTGCT 
ATGAGGGCCT TCCAGAACAC GGCAACTGCA TGTGCACCAG TATCACATTA TCGAGCTGTT 
GAAAGTGTGG ATTCAAGTGA AGAAAGTTTT TCTGATTCAG ATGATGATAG CTGTCTTTGG 
AAACGCAAAC GACAGAAATG TTTTAACCCT CCTCCCAAAC CAGAGCCTTT TCAGTTTGGC 
CAGAGCAGTC AGAAACCACC TGTTGCTGGA GGAAAGAAGA TTAACAACAT ATGGGGTGCT 
GTGCTGCAGG AACAGAATCA AGATGCAGTG GCCACTGAAC TTGGTATCTT GGGAATGGAG 
GGCACTATTG ACAGAAGCAG ACAATCCGAG ACCTACAATT ATTTGCTTGC CAAGAAACTT 
AGGAAGGAAT CTCAAGAGCA TACAAAAGAT CTAGACAAGG AACTAGATGA ATATATGCAT 
GGTGGCAAAA AAATGGGATC AAAGGAAGAG GAAAATGGGC AAGGTCATCT CAAAAGGAAA 
CGACCTGTCA AAGACAGGCT AGGGAACAGA CCAGAAATGA ACTATAAAGG TCGATACGAG 
ATCACAGCGG AAGATTCTCA AGAGAAAGTG GCTGATGAAA TTTCATTCAG GTTACAGGAA 
CCAAAGAAAG ACCTGATAGC CCGAGTAGTG AGGATTATTG GTAACAAAAA GGCAATTGAA 
CTTCTGATGG AAACCGCTGA AGTTGAACAA AATGGTGGTC TCTTTATAAT GAATGGTAGT 
CGAAGAAGAA CACCAGGTGG AGTTTTTCTG AATCTCTTGA AAAACACTCC TAGTATCAGC 
GAGGAACAAA TTAAGGACAT TTTCTACATT GAAAACCAAA AGGAATATGA AAATAAAAAA 
GCTGCTAGGA AGAGGAGAAC ACAAGTGTTG GGGAAAAAGA TGAAACAAGC TATTAAAAGT 
CTAAATTTTC AAGAAGATGA TGATACATCA CGAGAAACTT TTGCAAGTGA CACGAATGAG 
GCCTTGGCCT CTCTTGATGA GTCACAGGAA GGACATGCAG AAGCCAAGTT GGAGGCAGAG 
GAAGCCATTG AAGTTGATCA TTCTCATGAT TTGGACATCT TTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115553.2
CDS	17..1201
Translation	MALEVGDMEDGQLSDSDSDMTVAPSDRPLQLPKVLGGDSAMRAFQNTATACAPVSHYRAVESVDSSEESFSDSDDDSCLWKRKRQKCFNPPPKPEPFQFGQSSQKPPVAGGKKINNIWGAVLQEQNQDAVATELGILGMEGTIDRSRQSETYNYLLAKKLRKESQEHTKDLDKELDEYMHGGKKMGSKEEENGQGHLKRKRPVKDRLGNRPEMNYKGRYEITAEDSQEKVADEISFRLQEPKKDLIARVVRIIGNKKAIELLMETAEVEQNGGLFIMNGSRRRTPGGVFLNLLKNTPSISEEQIKDIFYIENQKEYENKKAARKRRTQVLGKKMKQAIKSLNFQEDDDTSRETFASDTNEALASLDESQEGHAEAKLEAEEAIEVDHSHDLDIF

Target ORF information:

RefSeq Version	NM_032177.4
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphorylated adaptor for RNA export (PHAX), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032177.4

ORF Insert Sequence:

ATGGCGTTGG AGGTCGGCGA TATGGAAGAT GGGCAGCTTT CCGACTCGGA TTCCGACATG 
ACGGTCGCAC CCAGCGACAG GCCGCTGCAA TTGCCAAAAG TGCTAGGTGG CGACAGTGCT 
ATGAGGGCCT TCCAGAACAC GGCAACTGCA TGTGCACCAG TATCACATTA TCGAGCTGTT 
GAAAGTGTGG ATTCAAGTGA AGAAAGTTTT TCTGATTCAG ATGATGATAG CTGTCTTTGG 
AAACGCAAAC GACAGAAATG TTTTAACCCT CCTCCCAAAC CAGAGCCTTT TCAGTTTGGC 
CAGAGCAGTC AGAAACCACC TGTTGCTGGA GGAAAGAAGA TTAACAACAT ATGGGGTGCT 
GTGCTGCAGG AACAGAATCA AGATGCAGTG GCCACTGAAC TTGGTATCTT GGGAATGGAG 
GGCACTATTG ACAGAAGCAG ACAATCCGAG ACCTACAATT ATTTGCTTGC CAAGAAACTT 
AGGAAGGAAT CTCAAGAGCA TACAAAAGAT CTAGACAAGG AACTAGATGA ATATATGCAT 
GGTGGCAAAA AAATGGGATC AAAGGAAGAG GAAAATGGGC AAGGTCATCT CAAAAGGAAA 
CGACCTGTCA AAGACAGGCT AGGGAACAGA CCAGAAATGA ACTATAAAGG TCGATACGAG 
ATCACAGCGG AAGATTCTCA AGAGAAAGTG GCTGATGAAA TTTCATTCAG GTTACAGGAA 
CCAAAGAAAG ACCTGATAGC CCGAGTAGTG AGGATTATTG GTAACAAAAA GGCAATTGAA 
CTTCTGATGG AAACCGCTGA AGTTGAACAA AATGGTGGTC TCTTTATAAT GAATGGTAGT 
CGAAGAAGAA CACCAGGTGG AGTTTTTCTG AATCTCTTGA AAAACACTCC TAGTATCAGC 
GAGGAACAAA TTAAGGACAT TTTCTACATT GAAAACCAAA AGGAATATGA AAATAAAAAA 
GCTGCTAGGA AGAGGAGAAC ACAAGTGTTG GGGAAAAAGA TGAAACAAGC TATTAAAAGT 
CTAAATTTTC AAGAAGATGA TGATACATCA CGAGAAACTT TTGCAAGTGA CACGAATGAG 
GCCTTGGCCT CTCTTGATGA GTCACAGGAA GGACATGCAG AAGCCAAGTT GGAGGCAGAG 
GAAGCCATTG AAGTTGATCA TTCTCATGAT TTGGACATCT TTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3.
Nature communications68192(2015 Sep)
Gebhardt A,Habjan M,Benda C,Meiler A,Haas DA,Hein MY,Mann A,Mann M,Habermann B,Pichlmair A

Structure and RNA recognition by the snRNA and snoRNA transport factor PHAX.
RNA (New York, N.Y.)16(6)1205-16(2010 Jun)
Mourão A,Varrot A,Mackereth CD,Cusack S,Sattler M

Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies.
Molecular biology of the cell17(7)3221-31(2006 Jul)
Lemm I,Girard C,Kuhn AN,Watkins NJ,Schneider M,Bordonné R,Lührmann R

PHAX and CRM1 are required sequentially to transport U3 snoRNA to nucleoli.
Molecular cell16(5)777-87(2004 Dec)
Boulon S,Verheggen C,Jady BE,Girard C,Pescia C,Paul C,Ospina JK,Kiss T,Matera AG,Bordonné R,Bertrand E

Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex.
Molecular cell16(5)789-98(2004 Dec)
Watkins NJ,Lemm I,Ingelfinger D,Schneider C,Hossbach M,Urlaub H,Lührmann R

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PHAX cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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