PAX1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PAX1
Entrez Gene ID	5075
Full Name	paired box 1
Synonyms	HUP48,OFC2
General protein information	Preferred Names paired box 1 Names paired box protein Pax-1 paired box gene 1 paired domain gene HuP48
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20p11.22
Summary	This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012].
Disorder MIM:	167411
Disorder Html:	?Otofaciocervical syndrome 2, 615560 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_006192.4	NP_006183.2	paired box protein Pax-1 isoform 1
NM_006192.5	NP_006183.2	paired box protein Pax-1 isoform 1
NM_001257096.1	NP_001244025.1	paired box protein Pax-1 isoform 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	PAX1	XP_002692205.2
Macaca mulatta (Rhesus monkey)	PAX1	XP_001095275.2
Mus musculus (house mouse)	Pax1	NP_032806.2
Canis lupus familiaris (dog)	PAX1	XP_542866.3
Danio rerio (zebrafish)	pax1b	XP_700877.6
Gallus gallus (chicken)	PAX1	XP_003640945.2
Homo sapiens (human)	PAX1	NP_001244025.1
Danio rerio (zebrafish)	pax1a	NP_001074061.1
Xenopus tropicalis (tropical clawed frog)	pax1	XP_002939483.2

Gene Ontology
Bibliography

Related articles in PubMed

Association between dense PAX1 promoter methylation and HPV16 infection in cervical squamous epithelial neoplasms of Xin Jiang Uyghur and Han women.
Zhang L, Hu D, Wang S, Zhang Y, Pang L, Tao L, Jia W
Gene723144142(2020 Jan)

Genetic polymorphisms of PAX1 are functionally associated with different PUMC types of adolescent idiopathic scoliosis in a northern Chinese Han population.
Liu G, Liu S, Li X, Chen J, Chen W, Zuo Y, Liu J, Niu Y, Lin M, Zhao S, Long B, Zhao Y, Ye Y, Zhang J, Shen J, Qiu G, Wu Z, Wu N
Gene688215-220(2019 Mar)

Autosomal recessive otofaciocervical syndrome type 2 with novel homozygous small insertion in PAX1 gene.
Patil SJ, Das Bhowmik A, Bhat V, Satidevi Vineeth V, Vasudevamurthy R, Dalal A
American journal of medical genetics. Part A176(5)1200-1206(2018 05)

Genetic Variant of PAX1 Gene Is Functionally Associated With Adolescent Idiopathic Scoliosis in the Chinese Population.
Xu L, Sheng F, Xia C, Qin X, Tang NL, Qiu Y, Cheng JC, Zhu Z
Spine43(7)492-496(2018 04)

Hypermethylated ZNF582 and PAX1 genes in oral scrapings collected from cancer-adjacent normal oral mucosal sites are associated with aggressive progression and poor prognosis of oral cancer.
Cheng SJ, Chang CF, Ko HH, Liu YC, Peng HH, Wang HJ, Lin HS, Chiang CP
Oral oncology75169-177(2017 12)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PAX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PAX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00720	NM_001257096.1 Latest version!	Homo sapiens paired box 1 (PAX1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu00320	NM_006192.5 Latest version!	Homo sapiens paired box 1 (PAX1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu00320	NM_006192.4	Homo sapiens paired box 1 (PAX1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PAX1 ( NM_001257096.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001244025.1 Homo sapiens paired box 1 (PAX1), transcript variant 2, mRNA.

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CloneID	OHu00720
Clone ID Related Accession (Same CDS sequence)	NM_001257096.1
Accession Version	NM_001257096.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573315200000
Organism	Homo sapiens(human)
Product	paired box protein Pax-1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL035562.14, BC143793.1 and AI167631.1. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 2, which has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC143791.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAGTTCA CCCTGGGCCT GGGGTCGCGG GCGTGGAGAG TGTCCTGGGA GGGGGCAGCA 
GCGGCGGCGG CAGGCCCTGG AGCGGGCGGC AGCGCGCTCC GCTGCCGCGC ACAGCGCGTC 
TCCAGCCCGC GGCTGGGCCG CCGCGGCTCT CGGCTCTCGG GCGCCCTCCC TCTATGCCTC 
TCACGCGGCG GCGGCGGCGC CCAAGCTCTC CCGGACTGCG CCGGGCCCAG CCCCGGCCAC 
CCCGGCCACC CCGGCGCCAG GCAGCTGGCC GGCCCGCTCG CTATGGAGCA GACGTATGGC 
GAGGTGAACC AGCTGGGCGG TGTGTTCGTC AACGGCCGCC CCCTGCCCAA CGCCATCCGC 
TTGCGCATTG TGGAGCTGGC GCAGCTGGGC ATCCGACCCT GTGACATCAG TCGGCAGCTC 
CGCGTATCCC ACGGCTGCGT GAGCAAGATC CTGGCGCGCT ACAACGAGAC CGGCTCCATT 
CTGCCCGGGG CCATCGGGGG GAGCAAGCCC CGCGTCACCA CTCCCAACGT GGTCAAGCAC 
ATCCGGGACT ACAAGCAAGG AGACCCTGGC ATCTTTGCCT GGGAGATCCG CGACCGGCTG 
CTGGCCGACG GCGTCTGTGA CAAGTACAAT GTGCCTTCGG TGAGCTCCAT CAGCCGCATC 
CTGCGCAACA AGATCGGCAG CCTGGCGCAG CCCGGACCGT ACGAGGCAAG TAAGCAGCCG 
CCGTCGCAGC CTACGCTGCC CTACAACCAC ATCTACCAGT ACCCCTACCC CAGTCCCGTG 
TCGCCCACGG GCGCCAAGAT GGGCAGCCAC CCCGGGGTCC CGGGCACGGC GGGCCACGTC 
AGCATCCCGC GCTCATGGCC CTCGGCACAC TCGGTCAGCA ACATCCTGGG CATCCGGACG 
TTTATGGAGC AAACAGGGGC CCTGGCTGGG AGCGAAGGCA CCGCTTACTC TCCCAAGATG 
GAAGACTGGG CCGGCGTGAA CCGCACGGCC TTCCCCGCCA CCCCCGCAGT GAATGGGCTA 
GAGAAACCTG CCTTAGAGGC AGACATTAAA TACACTCAGT CGGCCTCCAC CCTCTCTGCC 
GTGGGCGGCT TTCTCCCCGC CTGCGCCTAC CCGGCCTCCA ACCAGCACGG CGTGTACAGC 
GCCCCGGGCG GCGGCTACCT CGCCCCGGGC CCGCCGTGGC CGCCTGCGCA AGGTCCTCCT 
CTGGCGCCCC CCGGGGCCGG CGTAGCTGTG CATGGCGGGG AACTCGCGGC AGCAATGACC 
TTCAAGCATC CCAGCCGAGA AGTGGCTGAC AGGAAGCCTC CCAGCTCCGG CAGCAAGGCC 
CCGGACGCCC TCAGTAGCTT ACACGGACTG CCCATCCCGG CCTCGACCTC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001244025.1
CDS	55..1428
Translation	MKFTLGLGSRAWRVSWEGAAAAAAGPGAGGSALRCRAQRVSSPRLGRRGSRLSGALPLCLSRGGGGAQALPDCAGPSPGHPGHPGARQLAGPLAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGSLAQPGPYEASKQPPSQPTLPYNHIYQYPYPSPVSPTGAKMGSHPGVPGTAGHVSIPRSWPSAHSVSNILGIRTFMEQTGALAGSEGTAYSPKMEDWAGVNRTAFPATPAVNGLEKPALEADIKYTQSASTLSAVGGFLPACAYPASNQHGVYSAPGGGYLAPGPPWPPAQGPPLAPPGAGVAVHGGELAAAMTFKHPSREVADRKPPSSGSKAPDALSSLHGLPIPASTS

Target ORF information:

RefSeq Version	NM_001257096.1
Organism	Homo sapiens(human)
Definition	Homo sapiens paired box 1 (PAX1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001257096.1

ORF Insert Sequence:

ATGAAGTTCA CCCTGGGCCT GGGGTCGCGG GCGTGGAGAG TGTCCTGGGA GGGGGCAGCA 
GCGGCGGCGG CAGGCCCTGG AGCGGGCGGC AGCGCGCTCC GCTGCCGCGC ACAGCGCGTC 
TCCAGCCCGC GGCTGGGCCG CCGCGGCTCT CGGCTCTCGG GCGCCCTCCC TCTATGCCTC 
TCACGCGGCG GCGGCGGCGC CCAAGCTCTC CCGGACTGCG CCGGGCCCAG CCCCGGCCAC 
CCCGGCCACC CCGGCGCCAG GCAGCTGGCC GGCCCGCTCG CTATGGAGCA GACGTATGGC 
GAGGTGAACC AGCTGGGCGG TGTGTTCGTC AACGGCCGCC CCCTGCCCAA CGCCATCCGC 
TTGCGCATTG TGGAGCTGGC GCAGCTGGGC ATCCGACCCT GTGACATCAG TCGGCAGCTC 
CGCGTATCCC ACGGCTGCGT GAGCAAGATC CTGGCGCGCT ACAACGAGAC CGGCTCCATT 
CTGCCCGGGG CCATCGGGGG GAGCAAGCCC CGCGTCACCA CTCCCAACGT GGTCAAGCAC 
ATCCGGGACT ACAAGCAAGG AGACCCTGGC ATCTTTGCCT GGGAGATCCG CGACCGGCTG 
CTGGCCGACG GCGTCTGTGA CAAGTACAAT GTGCCTTCGG TGAGCTCCAT CAGCCGCATC 
CTGCGCAACA AGATCGGCAG CCTGGCGCAG CCCGGACCGT ACGAGGCAAG TAAGCAGCCG 
CCGTCGCAGC CTACGCTGCC CTACAACCAC ATCTACCAGT ACCCCTACCC CAGTCCCGTG 
TCGCCCACGG GCGCCAAGAT GGGCAGCCAC CCCGGGGTCC CGGGCACGGC GGGCCACGTC 
AGCATCCCGC GCTCATGGCC CTCGGCACAC TCGGTCAGCA ACATCCTGGG CATCCGGACG 
TTTATGGAGC AAACAGGGGC CCTGGCTGGG AGCGAAGGCA CCGCTTACTC TCCCAAGATG 
GAAGACTGGG CCGGCGTGAA CCGCACGGCC TTCCCCGCCA CCCCCGCAGT GAATGGGCTA 
GAGAAACCTG CCTTAGAGGC AGACATTAAA TACACTCAGT CGGCCTCCAC CCTCTCTGCC 
GTGGGCGGCT TTCTCCCCGC CTGCGCCTAC CCGGCCTCCA ACCAGCACGG CGTGTACAGC 
GCCCCGGGCG GCGGCTACCT CGCCCCGGGC CCGCCGTGGC CGCCTGCGCA AGGTCCTCCT 
CTGGCGCCCC CCGGGGCCGG CGTAGCTGTG CATGGCGGGG AACTCGCGGC AGCAATGACC 
TTCAAGCATC CCAGCCGAGA AGTGGCTGAC AGGAAGCCTC CCAGCTCCGG CAGCAAGGCC 
CCGGACGCCC TCAGTAGCTT ACACGGACTG CCCATCCCGG CCTCGACCTC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAX1 ( NM_006192.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006183.2 Homo sapiens paired box 1 (PAX1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00320
Clone ID Related Accession (Same CDS sequence)	NM_006192.4 , NM_006192.5
Accession Version	NM_006192.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1605bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1549641600000
Organism	Homo sapiens(human)
Product	paired box protein Pax-1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL035562.14, BC069134.1 and AI167631.1. This sequence is a reference standard in the RefSeqGene project. On Mar 13, 2012 this sequence version replaced NM_006192.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2157437 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGTTCA CCCTGGGCCT GGGGTCGCGG GCGTGGAGAG TGTCCTGGGA GGGGGCAGCA 
GCGGCGGCGG CAGGCCCTGG AGCGGGCGGC AGCGCGCTCC GCTGCCGCGC ACAGCGCGTC 
TCCAGCCCGC GGCTGGGCCG CCGCGGCTCT CGGCTCTCGG GCGCCCTCCC TCTATGCCTC 
TCACGCGGCG GCGGCGGCGC CCAAGCTCTC CCGGACTGCG CCGGGCCCAG CCCCGGCCAC 
CCCGGCCACC CCGGCGCCAG GCAGCTGGCC GGCCCGCTCG CTATGGAGCA GACGTATGGC 
GAGGTGAACC AGCTGGGCGG TGTGTTCGTC AACGGCCGCC CCCTGCCCAA CGCCATCCGC 
TTGCGCATTG TGGAGCTGGC GCAGCTGGGC ATCCGACCCT GTGACATCAG TCGGCAGCTC 
CGCGTATCCC ACGGCTGCGT GAGCAAGATC CTGGCGCGCT ACAACGAGAC CGGCTCCATT 
CTGCCCGGGG CCATCGGGGG GAGCAAGCCC CGCGTCACCA CTCCCAACGT GGTCAAGCAC 
ATCCGGGACT ACAAGCAAGG AGACCCTGGC ATCTTTGCCT GGGAGATCCG CGACCGGCTG 
CTGGCCGACG GCGTCTGTGA CAAGTACAAT GTGCCTTCGG TGAGCTCCAT CAGCCGCATC 
CTGCGCAACA AGATCGGCAG CCTGGCGCAG CCCGGACCGT ACGAGGCAAG TAAGCAGCCG 
CCGTCGCAGC CTACGCTGCC CTACAACCAC ATCTACCAGT ACCCCTACCC CAGTCCCGTG 
TCGCCCACGG GCGCCAAGAT GGGCAGCCAC CCCGGGGTCC CGGGCACGGC GGGCCACGTC 
AGCATCCCGC GCTCATGGCC CTCGGCACAC TCGGTCAGCA ACATCCTGGG CATCCGGACG 
TTTATGGAGC AAACAGGGGC CCTGGCTGGG AGCGAAGGCA CCGCTTACTC TCCCAAGATG 
GAAGACTGGG CCGGCGTGAA CCGCACGGCC TTCCCCGCCA CCCCCGCAGT GAATGGGCTA 
GAGAAACCTG CCTTAGAGGC AGACATTAAA TACACTCAGT CGGCCTCCAC CCTCTCTGCC 
GTGGGCGGCT TTCTCCCCGC CTGCGCCTAC CCGGCCTCCA ACCAGCACGG CGTGTACAGC 
GCCCCGGGCG GCGGCTACCT CGCCCCGGGC CCGCCGTGGC CGCCTGCGCA AGGTCCTCCT 
CTGGCGCCCC CCGGGGCCGG CGTAGCTGTG CATGGCGGGG AACTCGCGGC AGCAATGACC 
TTCAAGCATC CCAGCCGAGA AGGAAGCCTC CCAGCTCCGG CAGCAAGGCC CCGGACGCCC 
TCAGTAGCTT ACACGGACTG CCCATCCCGG CCTCGACCTC CTAGGGGCAG CTCTCCCCGG 
ACCCGAGCCC GGAGGGAACG GCAGGCGGAC CCGGGCGCAC AGGTCTGCGC GGCGGCCCCG 
GCAATCGGCA CGGGCAGGAT CGGAGGACTC GCGGAGGAGG AAGCCAGTGC CGGCCCGCGG 
GGTGCACGCC CAGCCAGCCC CCAGGCCCAG CCCTGCCTCT GGCCGGACCC ACCACACTTC 
CTTTATTGGT CTGGGTTTTT AGGCTTCTCT GAACTTGGGT TTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006183.2
CDS	55..1659
Translation	MKFTLGLGSRAWRVSWEGAAAAAAGPGAGGSALRCRAQRVSSPRLGRRGSRLSGALPLCLSRGGGGAQALPDCAGPSPGHPGHPGARQLAGPLAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGSLAQPGPYEASKQPPSQPTLPYNHIYQYPYPSPVSPTGAKMGSHPGVPGTAGHVSIPRSWPSAHSVSNILGIRTFMEQTGALAGSEGTAYSPKMEDWAGVNRTAFPATPAVNGLEKPALEADIKYTQSASTLSAVGGFLPACAYPASNQHGVYSAPGGGYLAPGPPWPPAQGPPLAPPGAGVAVHGGELAAAMTFKHPSREGSLPAPAARPRTPSVAYTDCPSRPRPPRGSSPRTRARRERQADPGAQVCAAAPAIGTGRIGGLAEEEASAGPRGARPASPQAQPCLWPDPPHFLYWSGFLGFSELGF

Target ORF information:

RefSeq Version	NM_006192.4
Organism	Homo sapiens(human)
Definition	Homo sapiens paired box 1 (PAX1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006192.4

ORF Insert Sequence:

ATGAAGTTCA CCCTGGGCCT GGGGTCGCGG GCGTGGAGAG TGTCCTGGGA GGGGGCAGCA 
GCGGCGGCGG CAGGCCCTGG AGCGGGCGGC AGCGCGCTCC GCTGCCGCGC ACAGCGCGTC 
TCCAGCCCGC GGCTGGGCCG CCGCGGCTCT CGGCTCTCGG GCGCCCTCCC TCTATGCCTC 
TCACGCGGCG GCGGCGGCGC CCAAGCTCTC CCGGACTGCG CCGGGCCCAG CCCCGGCCAC 
CCCGGCCACC CCGGCGCCAG GCAGCTGGCC GGCCCGCTCG CTATGGAGCA GACGTATGGC 
GAGGTGAACC AGCTGGGCGG TGTGTTCGTC AACGGCCGCC CCCTGCCCAA CGCCATCCGC 
TTGCGCATTG TGGAGCTGGC GCAGCTGGGC ATCCGACCCT GTGACATCAG TCGGCAGCTC 
CGCGTATCCC ACGGCTGCGT GAGCAAGATC CTGGCGCGCT ACAACGAGAC CGGCTCCATT 
CTGCCCGGGG CCATCGGGGG GAGCAAGCCC CGCGTCACCA CTCCCAACGT GGTCAAGCAC 
ATCCGGGACT ACAAGCAAGG AGACCCTGGC ATCTTTGCCT GGGAGATCCG CGACCGGCTG 
CTGGCCGACG GCGTCTGTGA CAAGTACAAT GTGCCTTCGG TGAGCTCCAT CAGCCGCATC 
CTGCGCAACA AGATCGGCAG CCTGGCGCAG CCCGGACCGT ACGAGGCAAG TAAGCAGCCG 
CCGTCGCAGC CTACGCTGCC CTACAACCAC ATCTACCAGT ACCCCTACCC CAGTCCCGTG 
TCGCCCACGG GCGCCAAGAT GGGCAGCCAC CCCGGGGTCC CGGGCACGGC GGGCCACGTC 
AGCATCCCGC GCTCATGGCC CTCGGCACAC TCGGTCAGCA ACATCCTGGG CATCCGGACG 
TTTATGGAGC AAACAGGGGC CCTGGCTGGG AGCGAAGGCA CCGCTTACTC TCCCAAGATG 
GAAGACTGGG CCGGCGTGAA CCGCACGGCC TTCCCCGCCA CCCCCGCAGT GAATGGGCTA 
GAGAAACCTG CCTTAGAGGC AGACATTAAA TACACTCAGT CGGCCTCCAC CCTCTCTGCC 
GTGGGCGGCT TTCTCCCCGC CTGCGCCTAC CCGGCCTCCA ACCAGCACGG CGTGTACAGC 
GCCCCGGGCG GCGGCTACCT CGCCCCGGGC CCGCCGTGGC CGCCTGCGCA AGGTCCTCCT 
CTGGCGCCCC CCGGGGCCGG CGTAGCTGTG CATGGCGGGG AACTCGCGGC AGCAATGACC 
TTCAAGCATC CCAGCCGAGA AGGAAGCCTC CCAGCTCCGG CAGCAAGGCC CCGGACGCCC 
TCAGTAGCTT ACACGGACTG CCCATCCCGG CCTCGACCTC CTAGGGGCAG CTCTCCCCGG 
ACCCGAGCCC GGAGGGAACG GCAGGCGGAC CCGGGCGCAC AGGTCTGCGC GGCGGCCCCG 
GCAATCGGCA CGGGCAGGAT CGGAGGACTC GCGGAGGAGG AAGCCAGTGC CGGCCCGCGG 
GGTGCACGCC CAGCCAGCCC CCAGGCCCAG CCCTGCCTCT GGCCGGACCC ACCACACTTC 
CTTTATTGGT CTGGGTTTTT AGGCTTCTCT GAACTTGGGT TTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAX1 ( NM_006192.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_006183.2 Homo sapiens paired box 1 (PAX1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00320
Clone ID Related Accession (Same CDS sequence)	NM_006192.4 , NM_006192.5
Accession Version	NM_006192.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1605bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573315200000
Organism	Homo sapiens(human)
Product	paired box protein Pax-1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL035562.14, BC069134.1 and AI167631.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_006192.4. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2157437 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGTTCA CCCTGGGCCT GGGGTCGCGG GCGTGGAGAG TGTCCTGGGA GGGGGCAGCA 
GCGGCGGCGG CAGGCCCTGG AGCGGGCGGC AGCGCGCTCC GCTGCCGCGC ACAGCGCGTC 
TCCAGCCCGC GGCTGGGCCG CCGCGGCTCT CGGCTCTCGG GCGCCCTCCC TCTATGCCTC 
TCACGCGGCG GCGGCGGCGC CCAAGCTCTC CCGGACTGCG CCGGGCCCAG CCCCGGCCAC 
CCCGGCCACC CCGGCGCCAG GCAGCTGGCC GGCCCGCTCG CTATGGAGCA GACGTATGGC 
GAGGTGAACC AGCTGGGCGG TGTGTTCGTC AACGGCCGCC CCCTGCCCAA CGCCATCCGC 
TTGCGCATTG TGGAGCTGGC GCAGCTGGGC ATCCGACCCT GTGACATCAG TCGGCAGCTC 
CGCGTATCCC ACGGCTGCGT GAGCAAGATC CTGGCGCGCT ACAACGAGAC CGGCTCCATT 
CTGCCCGGGG CCATCGGGGG GAGCAAGCCC CGCGTCACCA CTCCCAACGT GGTCAAGCAC 
ATCCGGGACT ACAAGCAAGG AGACCCTGGC ATCTTTGCCT GGGAGATCCG CGACCGGCTG 
CTGGCCGACG GCGTCTGTGA CAAGTACAAT GTGCCTTCGG TGAGCTCCAT CAGCCGCATC 
CTGCGCAACA AGATCGGCAG CCTGGCGCAG CCCGGACCGT ACGAGGCAAG TAAGCAGCCG 
CCGTCGCAGC CTACGCTGCC CTACAACCAC ATCTACCAGT ACCCCTACCC CAGTCCCGTG 
TCGCCCACGG GCGCCAAGAT GGGCAGCCAC CCCGGGGTCC CGGGCACGGC GGGCCACGTC 
AGCATCCCGC GCTCATGGCC CTCGGCACAC TCGGTCAGCA ACATCCTGGG CATCCGGACG 
TTTATGGAGC AAACAGGGGC CCTGGCTGGG AGCGAAGGCA CCGCTTACTC TCCCAAGATG 
GAAGACTGGG CCGGCGTGAA CCGCACGGCC TTCCCCGCCA CCCCCGCAGT GAATGGGCTA 
GAGAAACCTG CCTTAGAGGC AGACATTAAA TACACTCAGT CGGCCTCCAC CCTCTCTGCC 
GTGGGCGGCT TTCTCCCCGC CTGCGCCTAC CCGGCCTCCA ACCAGCACGG CGTGTACAGC 
GCCCCGGGCG GCGGCTACCT CGCCCCGGGC CCGCCGTGGC CGCCTGCGCA AGGTCCTCCT 
CTGGCGCCCC CCGGGGCCGG CGTAGCTGTG CATGGCGGGG AACTCGCGGC AGCAATGACC 
TTCAAGCATC CCAGCCGAGA AGGAAGCCTC CCAGCTCCGG CAGCAAGGCC CCGGACGCCC 
TCAGTAGCTT ACACGGACTG CCCATCCCGG CCTCGACCTC CTAGGGGCAG CTCTCCCCGG 
ACCCGAGCCC GGAGGGAACG GCAGGCGGAC CCGGGCGCAC AGGTCTGCGC GGCGGCCCCG 
GCAATCGGCA CGGGCAGGAT CGGAGGACTC GCGGAGGAGG AAGCCAGTGC CGGCCCGCGG 
GGTGCACGCC CAGCCAGCCC CCAGGCCCAG CCCTGCCTCT GGCCGGACCC ACCACACTTC 
CTTTATTGGT CTGGGTTTTT AGGCTTCTCT GAACTTGGGT TTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006183.2
CDS	50..1654
Translation	MKFTLGLGSRAWRVSWEGAAAAAAGPGAGGSALRCRAQRVSSPRLGRRGSRLSGALPLCLSRGGGGAQALPDCAGPSPGHPGHPGARQLAGPLAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGSLAQPGPYEASKQPPSQPTLPYNHIYQYPYPSPVSPTGAKMGSHPGVPGTAGHVSIPRSWPSAHSVSNILGIRTFMEQTGALAGSEGTAYSPKMEDWAGVNRTAFPATPAVNGLEKPALEADIKYTQSASTLSAVGGFLPACAYPASNQHGVYSAPGGGYLAPGPPWPPAQGPPLAPPGAGVAVHGGELAAAMTFKHPSREGSLPAPAARPRTPSVAYTDCPSRPRPPRGSSPRTRARRERQADPGAQVCAAAPAIGTGRIGGLAEEEASAGPRGARPASPQAQPCLWPDPPHFLYWSGFLGFSELGF

Target ORF information:

RefSeq Version	NM_006192.5
Organism	Homo sapiens(human)
Definition	Homo sapiens paired box 1 (PAX1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006192.5

ORF Insert Sequence:

ATGAAGTTCA CCCTGGGCCT GGGGTCGCGG GCGTGGAGAG TGTCCTGGGA GGGGGCAGCA 
GCGGCGGCGG CAGGCCCTGG AGCGGGCGGC AGCGCGCTCC GCTGCCGCGC ACAGCGCGTC 
TCCAGCCCGC GGCTGGGCCG CCGCGGCTCT CGGCTCTCGG GCGCCCTCCC TCTATGCCTC 
TCACGCGGCG GCGGCGGCGC CCAAGCTCTC CCGGACTGCG CCGGGCCCAG CCCCGGCCAC 
CCCGGCCACC CCGGCGCCAG GCAGCTGGCC GGCCCGCTCG CTATGGAGCA GACGTATGGC 
GAGGTGAACC AGCTGGGCGG TGTGTTCGTC AACGGCCGCC CCCTGCCCAA CGCCATCCGC 
TTGCGCATTG TGGAGCTGGC GCAGCTGGGC ATCCGACCCT GTGACATCAG TCGGCAGCTC 
CGCGTATCCC ACGGCTGCGT GAGCAAGATC CTGGCGCGCT ACAACGAGAC CGGCTCCATT 
CTGCCCGGGG CCATCGGGGG GAGCAAGCCC CGCGTCACCA CTCCCAACGT GGTCAAGCAC 
ATCCGGGACT ACAAGCAAGG AGACCCTGGC ATCTTTGCCT GGGAGATCCG CGACCGGCTG 
CTGGCCGACG GCGTCTGTGA CAAGTACAAT GTGCCTTCGG TGAGCTCCAT CAGCCGCATC 
CTGCGCAACA AGATCGGCAG CCTGGCGCAG CCCGGACCGT ACGAGGCAAG TAAGCAGCCG 
CCGTCGCAGC CTACGCTGCC CTACAACCAC ATCTACCAGT ACCCCTACCC CAGTCCCGTG 
TCGCCCACGG GCGCCAAGAT GGGCAGCCAC CCCGGGGTCC CGGGCACGGC GGGCCACGTC 
AGCATCCCGC GCTCATGGCC CTCGGCACAC TCGGTCAGCA ACATCCTGGG CATCCGGACG 
TTTATGGAGC AAACAGGGGC CCTGGCTGGG AGCGAAGGCA CCGCTTACTC TCCCAAGATG 
GAAGACTGGG CCGGCGTGAA CCGCACGGCC TTCCCCGCCA CCCCCGCAGT GAATGGGCTA 
GAGAAACCTG CCTTAGAGGC AGACATTAAA TACACTCAGT CGGCCTCCAC CCTCTCTGCC 
GTGGGCGGCT TTCTCCCCGC CTGCGCCTAC CCGGCCTCCA ACCAGCACGG CGTGTACAGC 
GCCCCGGGCG GCGGCTACCT CGCCCCGGGC CCGCCGTGGC CGCCTGCGCA AGGTCCTCCT 
CTGGCGCCCC CCGGGGCCGG CGTAGCTGTG CATGGCGGGG AACTCGCGGC AGCAATGACC 
TTCAAGCATC CCAGCCGAGA AGGAAGCCTC CCAGCTCCGG CAGCAAGGCC CCGGACGCCC 
TCAGTAGCTT ACACGGACTG CCCATCCCGG CCTCGACCTC CTAGGGGCAG CTCTCCCCGG 
ACCCGAGCCC GGAGGGAACG GCAGGCGGAC CCGGGCGCAC AGGTCTGCGC GGCGGCCCCG 
GCAATCGGCA CGGGCAGGAT CGGAGGACTC GCGGAGGAGG AAGCCAGTGC CGGCCCGCGG 
GGTGCACGCC CAGCCAGCCC CCAGGCCCAG CCCTGCCTCT GGCCGGACCC ACCACACTTC 
CTTTATTGGT CTGGGTTTTT AGGCTTCTCT GAACTTGGGT TTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Association between dense PAX1 promoter methylation and HPV16 infection in cervical squamous epithelial neoplasms of Xin Jiang Uyghur and Han women.
Gene723144142(2020 Jan)
Zhang L,Hu D,Wang S,Zhang Y,Pang L,Tao L,Jia W

Genetic polymorphisms of PAX1 are functionally associated with different PUMC types of adolescent idiopathic scoliosis in a northern Chinese Han population.
Gene688215-220(2019 Mar)
Liu G,Liu S,Li X,Chen J,Chen W,Zuo Y,Liu J,Niu Y,Lin M,Zhao S,Long B,Zhao Y,Ye Y,Zhang J,Shen J,Qiu G,Wu Z,Wu N

Autosomal recessive otofaciocervical syndrome type 2 with novel homozygous small insertion in PAX1 gene.
American journal of medical genetics. Part A176(5)1200-1206(2018 05)
Patil SJ,Das Bhowmik A,Bhat V,Satidevi Vineeth V,Vasudevamurthy R,Dalal A

Genetic Variant of PAX1 Gene Is Functionally Associated With Adolescent Idiopathic Scoliosis in the Chinese Population.
Spine43(7)492-496(2018 04)
Xu L,Sheng F,Xia C,Qin X,Tang NL,Qiu Y,Cheng JC,Zhu Z

Hypermethylated ZNF582 and PAX1 genes in oral scrapings collected from cancer-adjacent normal oral mucosal sites are associated with aggressive progression and poor prognosis of oral cancer.
Oral oncology75169-177(2017 12)
Cheng SJ,Chang CF,Ko HH,Liu YC,Peng HH,Wang HJ,Lin HS,Chiang CP

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PAX1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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