| Gene Symbol | LPL |
| Entrez Gene ID | 4023 |
| Full Name | lipoprotein lipase |
| Synonyms | HDLCQ11,LIPD |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]. |
| Disorder MIM: | |
| Disorder Html: | Lipoprotein lipase deficiency, 238600 (3); Combined hyperlipidemia, familial, 144250 (3); [High density lipoprotein cholesterol level QTL 11] (3) |
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