GRID2IP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GRID2IP
Entrez Gene ID	392862
Full Name	Grid2 interacting protein
Synonyms	DELPHILIN
General protein information	Preferred Names Grid2 interacting protein Names delphilin glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1 glutamate receptor, ionotropic, delta 2-interacting protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p22.1
Summary	Glutamate receptor delta-2 (GRID2; MIM 602368) is predominantly expressed at parallel fiber-Purkinje cell postsynapses and plays crucial roles in synaptogenesis and synaptic plasticity. GRID2IP1 interacts with GRID2 and may control GRID2 signaling in Purkinje cells (Matsuda et al., 2006 [PubMed 16835239]).[supplied by OMIM, Mar 2008].
Disorder MIM:	610639

mRNA and Protein(s)

mRNA	Protein	Name
XM_011515404.2	XP_011513706.1	delphilin isoform X1
NM_001145118.1	NP_001138590.1	delphilin

Pathways from BioSystems

Homologies

Homo sapiens (human)	GRID2IP	NP_001138590.1
Mus musculus (house mouse)	Grid2ip	NP_001152793.1
Macaca mulatta (Rhesus monkey)	GRID2IP	XP_002803248.1
Gallus gallus (chicken)	GRID2IP	XP_425245.4
Danio rerio (zebrafish)	LOC561017	XP_002661187.2
Canis lupus familiaris (dog)	GRID2IP	XP_005621181.1
Xenopus tropicalis (tropical clawed frog)	grid2ip	NP_001072613.1
Pan troglodytes (chimpanzee)	GRID2IP	XP_003318349.1
Bos taurus (cattle)	GRID2IP	NP_001179409.1
Rattus norvegicus (Norway rat)	Grid2ip	NP_001099380.1

Gene Ontology
Bibliography

Related articles in PubMed

Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts.
Ek WE, Reznichenko A, Ripke S, Niesler B, Zucchelli M, Rivera NV, Schmidt PT, Pedersen NL, Magnusson P, Talley NJ, Holliday EG, Houghton L, Gazouli M, Karamanolis G, Rappold G, Burwinkel B, Surowy H, Rafter J, Assadi G, Li L, Papadaki E, Gambaccini D, Marchi S, Colucci R, Blandizzi C, Barbaro R, Karling P, Walter S, Ohlsson B, Tornblom H, Bresso F, Andreasson A, Dlugosz A, Simren M, Agreus L, Lindberg G, Boeckxstaens G, Bellini M, Stanghellini V, Barbara G, Daly MJ, Camilleri M, Wouters MM, D'Amato M
Gut64(11)1774-82(2015 Nov)

Binding of glutamate receptor delta2 to its scaffold protein, Delphilin, is regulated by PKA.
Sonoda T, Mochizuki C, Yamashita T, Watanabe-Kaneko K, Miyagi Y, Shigeri Y, Yazama F, Okuda K, Kawamoto S
Biochemical and biophysical research communications350(3)748-52(2006 Nov)

Characterization of the delta2 glutamate receptor-binding protein delphilin: Splicing variants with differential palmitoylation and an additional PDZ domain.
Matsuda K, Matsuda S, Gladding CM, Yuzaki M
The Journal of biological chemistry281(35)25577-87(2006 Sep)

Identification and characterization of human GRID2IP gene and rat Grid2ip gene in silico.
Katoh M, Katoh M
International journal of molecular medicine12(6)1015-9(2003 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GRID2IP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GRID2IP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu80071	XM_011515404.2 Latest version!	Homo sapiens Grid2 interacting protein (GRID2IP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OHu01950	NM_001145118.1 Latest version!	Homo sapiens Grid2 interacting protein (GRID2IP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$853.30 $1219.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GRID2IP ( XM_011515404.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011513706.1 Homo sapiens Grid2 interacting protein (GRID2IP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu80071
Clone ID Related Accession (Same CDS sequence)	XM_011515404.2
Accession Version	XM_011515404.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3084bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	delphilin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011515404.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAGG ACCAGGGCTT CTCTCGGCAC TTTCGGATCT TCATCCCCAA GAAGCACCGG 
GCGCGCTTCG ACGAGGTGGT GTCTCAGGGC CTCCTGGGCA AGCTGTGCCG CGCACGCCGG 
GCCCAGGGCG CGCAGCGACT GCGCCGGAGC CGCAGCGAGG AGCGGCCGGA GCGCCTCCTG 
GTGTCCACGC GCGCCAGCGC CCCGCCGCGC CGCCCCGATG AGCCGCCCCC GCGCAGGGCC 
TCCTTGCTGG TGGGCGGCCT CGCCGGCCCC GGGGGCGCGC GCAGGACTGT CCGAGTCTAC 
AAAGGCAACA AGAGCTTCGG CTTCACACTT CGCGGCCACG GGCCTGTCTG GATCGAGTCT 
GTCCTGCCTG GGAGCCCAGC TGACAATGCT GCCCTCAAGT CAGGTGACCG GATCCTCTTC 
CTCAATGGAC TGGACATGAG GAACTGCTCC CACGACAAGG TGGTGTCCAT GCTGCAGGGC 
AGTGGTGCCA TGCCCACGCT GGTGGTGGAG GAAGGGCTCG TCCCATTTGC CAGTGACTCC 
GATTCTCTGG ACTCACCCAA CCCGTCGTCG GCGCTCACCT CCCTGCAGTG GGTGGCGGAG 
ATCCTGCCGT CCAGCATCCG GGTCCAAGGG AGGACCTTCA GCCAGCAGCT GGAGCACCTA 
CTCACACCTC CTGAGCGCTA TGGGGTCTGC CGGGCCCTCG AGAGCTTCTT CCAGCACAGG 
AACATCGACA CCCTCATCGT TGACGTCTAC CCTGTGCTGG ACACCCCTGC CAAGCAGGTC 
CTGTGGCAGT TCATCTACCA GCTGCTGACC TATGAGGAGC AGGAGCTCTG TCAGGAGAAA 
ATCGCATGCT TCCTGGGCTA CACGGCCATG ACAGAGCCGG AGCCTGAGCT GGACCTGGAG 
TCCGAGCCCA CGCCTGAGCC CCAGCCGCGG AGCTCCCTGC GGGCTTCCTC CATGTGCCGC 
CGCAGCCTCC GGTCCCAGGG CCTGGAGGCC GGCCTCAGCT GCGGTCCCAG CGAGTGCCCT 
GAGATGCCTC TTCCCCTGAT CCCAGGCGAG CGCCAGGCAG GCGACGGCAC GTCCCTCCCT 
GAGACCCCCA ACCCCAAGAT GATGTCAGCC GTCTATGCAG AGCTTGAGTC TCGACTGAAC 
AGCAGCTTCA AAGGGAAGAT GGGGACCGTG TCCAAATCCC GGGCTTCCCC TCCAGGCCCC 
AGCCCAGCAG TCACCACAGG GCCCAGGACC CTGTCCGGCG TCTCATGGCC CAGCGAGCGA 
CTCTTGCCCT CCCCCTGCTA CCACCCGCTG TGTTCGGGGG GTCTGGCCTC CCCCAGCAGC 
TCTGAGTCCC ACCCCTACGC CAGCCTGGAC AGCAGCAGGG CACCCTCCCC ACAGCCAGGC 
CCCGGGCCCA TCTGCCCCGA CAGCCCCCCA AGCCCGGACC CCACCCGCCC GCCCAGCCGC 
AGGAAGCTCT TCACCTTCTC CCACCCTGTG CGAAGCCGCG ATACTGACCG CTTCCTGGAC 
GTGCTGAGCG AGCAGCTGGG CCCCCGGGTC ACCATCGTGG ATGATTTCCT GACCCCGGAG 
AACGACTACG AGGAGATGAG CTTCCATGAT GACCAGGGCA GCTTCGTAAC CAATGAGCGG 
AGCAGCGCCA GCGACTGCAT CAGCAGCAGT GAAGAAGGCA GCTCCCTGAC CTACTCCTCC 
ATCTCTGACC ACATCCCCCC ACCCCCGCTC AGCCCCCCAC CACCGCCACC CCTGCCTTTC 
CATGACGCTA AGCCCAGCTC CCGCAGCTCT GATGGTTCCC GGGGCCCTGC TCAGGCGCTG 
GCCAAGCCCC TCACCCAACT CAGCCACCCA GTCCCTCCAC CACCCCCACC GCCCCTGCCC 
CCACCCGTGC CCTGTGCACC CCCCATGCTG TCCCGGGGCC TGGGCCACCG GCGCAGTGAG 
ACCAGCCACA TGAGCGTCAA GCGCTTGCGG TGGGAACAGG TGGAGAACTC AGAAGGCACC 
ATCTGGGGTC AGCTCGGGGA AGACTCTGAC TACGATAAGC TGAGTGACAT GGTGAAATAC 
CTCGACCTGG AGCTCCACTT CGGCACCCAG AAACCTGCTA AACCGGTGCC GGGGCCGGAG 
CCCTTCCGGA AGAAGGAGGT GGTGGAGATC CTGTCCCATA AGAAGGCCTA CAACACCTCC 
ATCCTCTTGG CACACCTGAA GCTGAGCCCC GCGGAGCTGC GCCAGGTGCT GATGAGCATG 
GAGCCCCGGC GCCTGGAGCC CGCACATCTC GCGCAGCTGC TGCTCTTCGC GCCCGACGCC 
GACGAGGAGC AGCGCTACCA GGCCTTCCGC GAGGCGCCCG GCCGCCTCAG CGAGCCGGAC 
CAGTTCGTCC TGCAGATGCT GTCAGTTCCC GAATACAAGA CACGCCTGCG CAGCCTCCAC 
TTCCAGGCCA CCCTCCAGGA GAAGACAGAG GAGATCCGAG GCAGCCTTGA ATGCTTGCGC 
CAGGCCTCCC TGGAGCTCAA AAACAGTCGG AAGCTCGCCA AGATCCTGGA GTTTGTGTTG 
GCCATGGGCA ACTATCTCAA CGATGGACAG CCCAAAACCA ACAAGACTAC GGGCTTCAAG 
ATCAACTTTC TGACAGAGCT GAACTCCACC AAGACAGTGG ATGGGAAGTC CACCTTCCTG 
CACATCCTTG CCAAATCGCT GAGCCAGCAC TTCCCTGAAC TCCTGGGCTT TGCTCAGGAC 
CTGCCCACCG TGCCCCTGGC TGCCAAAGTG AACCAACGGG CCCTGACCAG TGACCTGGCT 
GACCTCCATG GCACTATCAG CGAGATACAG GATGCCTGCC AGAGCATTTC CCCCTCTAGC 
GAGGACAAGT TTGCAATGGT CATGTCGTCC TTCCTGGAGA CGGCCCAGCC AGCACTTCGG 
GCGCTCGACG GGCTGCAGCG CGAGGCCATG GAGGAGCTGG GCAAGGCGCT GGCCTTCTTT 
GGGGAGGATT CCAAGGCCAC CACCTCTGAG GCTTTCTTCG GCATCTTTGC AGAGTTCATG 
AGCAAATTCG AGCGAGCGCT GAGTGACCTG CAGGCCGGGG AGGGCCTGCG CAGCTCCGGG 
ATGGTTTCAC CCCTGGCCTG GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011513706.1
CDS	28..3111
Translation	MGKDQGFSRHFRIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPERLLVSTRASAPPRRPDEPPPRRASLLVGGLAGPGGARRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPADNAALKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFASDSDSLDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESFFQHRNIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMTEPEPELDLESEPTPEPQPRSSLRASSMCRRSLRSQGLEAGLSCGPSECPEMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKMGTVSKSRASPPGPSPAVTTGPRTLSGVSWPSERLLPSPCYHPLCSGGLASPSSSESHPYASLDSSRAPSPQPGPGPICPDSPPSPDPTRPPSRRKLFTFSHPVRSRDTDRFLDVLSEQLGPRVTIVDDFLTPENDYEEMSFHDDQGSFVTNERSSASDCISSSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDAKPSSRSSDGSRGPAQALAKPLTQLSHPVPPPPPPPLPPPVPCAPPMLSRGLGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPAKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTSDLADLHGTISEIQDACQSISPSSEDKFAMVMSSFLETAQPALRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFAEFMSKFERALSDLQAGEGLRSSGMVSPLAW

Target ORF information:

RefSeq Version	XM_011515404.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Grid2 interacting protein (GRID2IP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011515404.2

ORF Insert Sequence:

ATGGGGAAGG ACCAGGGCTT CTCTCGGCAC TTTCGGATCT TCATCCCCAA GAAGCACCGG 
GCGCGCTTCG ACGAGGTGGT GTCTCAGGGC CTCCTGGGCA AGCTGTGCCG CGCACGCCGG 
GCCCAGGGCG CGCAGCGACT GCGCCGGAGC CGCAGCGAGG AGCGGCCGGA GCGCCTCCTG 
GTGTCCACGC GCGCCAGCGC CCCGCCGCGC CGCCCCGATG AGCCGCCCCC GCGCAGGGCC 
TCCTTGCTGG TGGGCGGCCT CGCCGGCCCC GGGGGCGCGC GCAGGACTGT CCGAGTCTAC 
AAAGGCAACA AGAGCTTCGG CTTCACACTT CGCGGCCACG GGCCTGTCTG GATCGAGTCT 
GTCCTGCCTG GGAGCCCAGC TGACAATGCT GCCCTCAAGT CAGGTGACCG GATCCTCTTC 
CTCAATGGAC TGGACATGAG GAACTGCTCC CACGACAAGG TGGTGTCCAT GCTGCAGGGC 
AGTGGTGCCA TGCCCACGCT GGTGGTGGAG GAAGGGCTCG TCCCATTTGC CAGTGACTCC 
GATTCTCTGG ACTCACCCAA CCCGTCGTCG GCGCTCACCT CCCTGCAGTG GGTGGCGGAG 
ATCCTGCCGT CCAGCATCCG GGTCCAAGGG AGGACCTTCA GCCAGCAGCT GGAGCACCTA 
CTCACACCTC CTGAGCGCTA TGGGGTCTGC CGGGCCCTCG AGAGCTTCTT CCAGCACAGG 
AACATCGACA CCCTCATCGT TGACGTCTAC CCTGTGCTGG ACACCCCTGC CAAGCAGGTC 
CTGTGGCAGT TCATCTACCA GCTGCTGACC TATGAGGAGC AGGAGCTCTG TCAGGAGAAA 
ATCGCATGCT TCCTGGGCTA CACGGCCATG ACAGAGCCGG AGCCTGAGCT GGACCTGGAG 
TCCGAGCCCA CGCCTGAGCC CCAGCCGCGG AGCTCCCTGC GGGCTTCCTC CATGTGCCGC 
CGCAGCCTCC GGTCCCAGGG CCTGGAGGCC GGCCTCAGCT GCGGTCCCAG CGAGTGCCCT 
GAGATGCCTC TTCCCCTGAT CCCAGGCGAG CGCCAGGCAG GCGACGGCAC GTCCCTCCCT 
GAGACCCCCA ACCCCAAGAT GATGTCAGCC GTCTATGCAG AGCTTGAGTC TCGACTGAAC 
AGCAGCTTCA AAGGGAAGAT GGGGACCGTG TCCAAATCCC GGGCTTCCCC TCCAGGCCCC 
AGCCCAGCAG TCACCACAGG GCCCAGGACC CTGTCCGGCG TCTCATGGCC CAGCGAGCGA 
CTCTTGCCCT CCCCCTGCTA CCACCCGCTG TGTTCGGGGG GTCTGGCCTC CCCCAGCAGC 
TCTGAGTCCC ACCCCTACGC CAGCCTGGAC AGCAGCAGGG CACCCTCCCC ACAGCCAGGC 
CCCGGGCCCA TCTGCCCCGA CAGCCCCCCA AGCCCGGACC CCACCCGCCC GCCCAGCCGC 
AGGAAGCTCT TCACCTTCTC CCACCCTGTG CGAAGCCGCG ATACTGACCG CTTCCTGGAC 
GTGCTGAGCG AGCAGCTGGG CCCCCGGGTC ACCATCGTGG ATGATTTCCT GACCCCGGAG 
AACGACTACG AGGAGATGAG CTTCCATGAT GACCAGGGCA GCTTCGTAAC CAATGAGCGG 
AGCAGCGCCA GCGACTGCAT CAGCAGCAGT GAAGAAGGCA GCTCCCTGAC CTACTCCTCC 
ATCTCTGACC ACATCCCCCC ACCCCCGCTC AGCCCCCCAC CACCGCCACC CCTGCCTTTC 
CATGACGCTA AGCCCAGCTC CCGCAGCTCT GATGGTTCCC GGGGCCCTGC TCAGGCGCTG 
GCCAAGCCCC TCACCCAACT CAGCCACCCA GTCCCTCCAC CACCCCCACC GCCCCTGCCC 
CCACCCGTGC CCTGTGCACC CCCCATGCTG TCCCGGGGCC TGGGCCACCG GCGCAGTGAG 
ACCAGCCACA TGAGCGTCAA GCGCTTGCGG TGGGAACAGG TGGAGAACTC AGAAGGCACC 
ATCTGGGGTC AGCTCGGGGA AGACTCTGAC TACGATAAGC TGAGTGACAT GGTGAAATAC 
CTCGACCTGG AGCTCCACTT CGGCACCCAG AAACCTGCTA AACCGGTGCC GGGGCCGGAG 
CCCTTCCGGA AGAAGGAGGT GGTGGAGATC CTGTCCCATA AGAAGGCCTA CAACACCTCC 
ATCCTCTTGG CACACCTGAA GCTGAGCCCC GCGGAGCTGC GCCAGGTGCT GATGAGCATG 
GAGCCCCGGC GCCTGGAGCC CGCACATCTC GCGCAGCTGC TGCTCTTCGC GCCCGACGCC 
GACGAGGAGC AGCGCTACCA GGCCTTCCGC GAGGCGCCCG GCCGCCTCAG CGAGCCGGAC 
CAGTTCGTCC TGCAGATGCT GTCAGTTCCC GAATACAAGA CACGCCTGCG CAGCCTCCAC 
TTCCAGGCCA CCCTCCAGGA GAAGACAGAG GAGATCCGAG GCAGCCTTGA ATGCTTGCGC 
CAGGCCTCCC TGGAGCTCAA AAACAGTCGG AAGCTCGCCA AGATCCTGGA GTTTGTGTTG 
GCCATGGGCA ACTATCTCAA CGATGGACAG CCCAAAACCA ACAAGACTAC GGGCTTCAAG 
ATCAACTTTC TGACAGAGCT GAACTCCACC AAGACAGTGG ATGGGAAGTC CACCTTCCTG 
CACATCCTTG CCAAATCGCT GAGCCAGCAC TTCCCTGAAC TCCTGGGCTT TGCTCAGGAC 
CTGCCCACCG TGCCCCTGGC TGCCAAAGTG AACCAACGGG CCCTGACCAG TGACCTGGCT 
GACCTCCATG GCACTATCAG CGAGATACAG GATGCCTGCC AGAGCATTTC CCCCTCTAGC 
GAGGACAAGT TTGCAATGGT CATGTCGTCC TTCCTGGAGA CGGCCCAGCC AGCACTTCGG 
GCGCTCGACG GGCTGCAGCG CGAGGCCATG GAGGAGCTGG GCAAGGCGCT GGCCTTCTTT 
GGGGAGGATT CCAAGGCCAC CACCTCTGAG GCTTTCTTCG GCATCTTTGC AGAGTTCATG 
AGCAAATTCG AGCGAGCGCT GAGTGACCTG CAGGCCGGGG AGGGCCTGCG CAGCTCCGGG 
ATGGTTTCAC CCCTGGCCTG GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GRID2IP ( NM_001145118.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138590.1 Homo sapiens Grid2 interacting protein (GRID2IP), mRNA.

Price & Availability↑

CloneID	OHu01950
Clone ID Related Accession (Same CDS sequence)	NM_001145118.1
Accession Version	NM_001145118.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3636bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Homo sapiens(human)
Product	delphilin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC072052.6. On or before Feb 12, 2009 this sequence version replaced XR_041838.1, XR_018117.1, XR_041837.1, XR_017146.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGCCACCA CTGCCACGCC GGCCACGAAC CAGGGCTGGC CAGAGGACTT TGGCTTCCGG 
CTAGGTGGCT CTGGCCCCTG CTTCGTCCTG GAGGTGGCCA AGGGGAGCAG CGCGCATGCC 
GGAGGACTGC GGCCAGGAGA CCAGATCCTG GAGGTGGAGG GGCTGGCGGT GGGCGGTCTG 
AGCCGCGAGC GCCTCGTGCG CCTGGCACGG CGCTGCCCAC GTGTGCCGCC CAGTCTGGGC 
GTGCTCCCGG CTCCCGACGG TGGCCCCGGC CCAGGATCCG GCCCCGCGGC CCCGACCACA 
GTCTTGCGGG CCCCGCGGTG CGGCCGCGGC CTAGCTCTGG GCCGTGAGCT GCTTCGCCTG 
GCCGGCCGCA AGCGCCCGGA CGCGGTGCAC CGAGAGCGCA GGCGCAAGGC CCAAGAGTTC 
AGCCGCAAGG TGGATGAAAT CTTGGGGGAC CAGCCAACTG CCAAGGAGCA GGTGTTCGCT 
GCACTGAAGC AGTTTGCAGC TGAGCAGCGG GTGGATGATC TGGTGTGGAC TCTCACCCTG 
GCGCTGCCCC GAGAGGCCTG CGGGCCACTC CTGGACAACC TCAGGATCTT CATCCCCAAG 
AAGCACCGGG CGCGCTTCGA CGAGGTGGTG TCTCAGGGCC TCCTGGGCAA GCTGTGCCGC 
GCACGCCGGG CCCAGGGCGC GCAGCGACTG CGCCGGAGCC GCAGCGAGGA GCGGCCGGAG 
CGCCTCCTGG TGTCCACGCG CGCCAGCGCC CCGCCGCGCC GCCCCGATGA GCCGCCCCCG 
CGCAGGGCCT CCTTGCTGGT GGGCGGCCTC GCCGGCCCCG GGGGCGCGCG CAGGACTGTC 
CGAGTCTACA AAGGCAACAA GAGCTTCGGC TTCACACTTC GCGGCCACGG GCCTGTCTGG 
ATCGAGTCTG TCCTGCCTGG GAGCCCAGCT GACAATGCTG CCCTCAAGTC AGGTGACCGG 
ATCCTCTTCC TCAATGGACT GGACATGAGG AACTGCTCCC ACGACAAGGT GGTGTCCATG 
CTGCAGGGCA GTGGTGCCAT GCCCACGCTG GTGGTGGAGG AAGGGCTCGT CCCATTTGCC 
AGTGACTCCG ATTCTCTGGA CTCACCCAAC CCGTCGTCGG CGCTCACCTC CCTGCAGTGG 
GTGGCGGAGA TCCTGCCGTC CAGCATCCGG GTCCAAGGGA GGACCTTCAG CCAGCAGCTG 
GAGCACCTAC TCACACCTCC TGAGCGCTAT GGGGTCTGCC GGGCCCTCGA GAGCTTCTTC 
CAGCACAGGA ACATCGACAC CCTCATCGTT GACGTCTACC CTGTGCTGGA CACCCCTGCC 
AAGCAGGTCC TGTGGCAGTT CATCTACCAG CTGCTGACCT ATGAGGAGCA GGAGCTCTGT 
CAGGAGAAAA TCGCATGCTT CCTGGGCTAC ACGGCCATGA CAGCAGAGCC GGAGCCTGAG 
CTGGACCTGG AGTCCGAGCC CACGCCTGAG CCCCAGCCGC GGAGCTCCCT GCGGGCTTCC 
TCCATGTGCC GCCGCAGCCT CCGGTCCCAG GGCCTGGAGG CCGGCCTCAG CTGCGGTCCC 
AGCGAGTGCC CTGAGATGCC TCTTCCCCTG ATCCCAGGCG AGCGCCAGGC AGGCGACGGC 
ACGTCCCTCC CTGAGACCCC CAACCCCAAG ATGATGTCAG CCGTCTATGC AGAGCTTGAG 
TCTCGACTGA ACAGCAGCTT CAAAGGGAAG ATGGGGACCG TGTCCAAATC CCGGGCTTCC 
CCTCCAGGCC CCAGCCCAGC AGTCACCACA GGGCCCAGGA CCCTGTCCGG CGTCTCATGG 
CCCAGCGAGC GACTCTTGCC CTCCCCCTGC TACCACCCGC TGTGTTCGGG GGGTCTGGCC 
TCCCCCAGCA GCTCTGAGTC CCACCCCTAC GCCAGCCTGG ACAGCAGCAG GGCACCCTCC 
CCACAGCCAG GCCCCGGGCC CATCTGCCCC GACAGCCCCC CAAGCCCGGA CCCCACCCGC 
CCGCCCAGCC GCAGGAAGCT CTTCACCTTC TCCCACCCTG TGCGAAGCCG CGATACTGAC 
CGCTTCCTGG ACGTGCTGAG CGAGCAGCTG GGCCCCCGGG TCACCATCGT GGATGATTTC 
CTGACCCCGG AGAACGACTA CGAGGAGATG AGCTTCCATG ATGACCAGGG CAGCTTCGTA 
ACCAATGAGC GGAGCAGCGC CAGCGACTGC ATCAGCAGCA GTGAAGAAGG CAGCTCCCTG 
ACCTACTCCT CCATCTCTGA CCACATCCCC CCACCCCCGC TCAGCCCCCC ACCACCGCCA 
CCCCTGCCTT TCCATGACGC TAAGCCCAGC TCCCGCAGCT CTGATGGTTC CCGGGGCCCT 
GCTCAGGCGC TGGCCAAGCC CCTCACCCAA CTCAGCCACC CAGTCCCTCC ACCACCCCCA 
CCGCCCCTGC CCCCACCCGT GCCCTGTGCA CCCCCCATGC TGTCCCGGGG CCTGGGCCAC 
CGGCGCAGTG AGACCAGCCA CATGAGCGTC AAGCGCTTGC GGTGGGAACA GGTGGAGAAC 
TCAGAAGGCA CCATCTGGGG TCAGCTCGGG GAAGACTCTG ACTACGATAA GCTGAGTGAC 
ATGGTGAAAT ACCTCGACCT GGAGCTCCAC TTCGGCACCC AGAAACCTGC TAAACCGGTG 
CCGGGGCCGG AGCCCTTCCG GAAGAAGGAG GTGGTGGAGA TCCTGTCCCA TAAGAAGGCC 
TACAACACCT CCATCCTCTT GGCACACCTG AAGCTGAGCC CCGCGGAGCT GCGCCAGGTG 
CTGATGAGCA TGGAGCCCCG GCGCCTGGAG CCCGCACATC TCGCGCAGCT GCTGCTCTTC 
GCGCCCGACG CCGACGAGGA GCAGCGCTAC CAGGCCTTCC GCGAGGCGCC CGGCCGCCTC 
AGCGAGCCGG ACCAGTTCGT CCTGCAGATG CTGTCAGTTC CCGAATACAA GACACGCCTG 
CGCAGCCTCC ACTTCCAGGC CACCCTCCAG GAGAAGACAG AGGAGATCCG AGGCAGCCTT 
GAATGCTTGC GCCAGGCCTC CCTGGAGCTC AAAAACAGTC GGAAGCTCGC CAAGATCCTG 
GAGTTTGTGT TGGCCATGGG CAACTATCTC AACGATGGAC AGCCCAAAAC CAACAAGACT 
ACGGGCTTCA AGATCAACTT TCTGACAGAG CTGAACTCCA CCAAGACAGT GGATGGGAAG 
TCCACCTTCC TGCACATCCT TGCCAAATCG CTGAGCCAGC ACTTCCCTGA ACTCCTGGGC 
TTTGCTCAGG ACCTGCCCAC CGTGCCCCTG GCTGCCAAAG TGAACCAACG GGCCCTGACC 
AGTGACCTGG CTGACCTCCA TGGCACTATC AGCGAGATAC AGGATGCCTG CCAGAGCATT 
TCCCCCTCTA GCGAGGACAA GTTTGCAATG GTCATGTCGT CCTTCCTGGA GACGGCCCAG 
CCAGCACTTC GGGCGCTCGA CGGGCTGCAG CGCGAGGCCA TGGAGGAGCT GGGCAAGGCG 
CTGGCCTTCT TTGGGGAGGA TTCCAAGGCC ACCACCTCTG AGGCTTTCTT CGGCATCTTT 
GCAGAGTTCA TGAGCAAATT CGAGCGAGCG CTGAGTGACC TGCAGGCCGG GGAGGGCCTG 
CGCAGCTCCG GGATGGTTTC ACCCCTGGCC TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138590.1
CDS	1..3636
Translation	MATTATPATNQGWPEDFGFRLGGSGPCFVLEVAKGSSAHAGGLRPGDQILEVEGLAVGGLSRERLVRLARRCPRVPPSLGVLPAPDGGPGPGSGPAAPTTVLRAPRCGRGLALGRELLRLAGRKRPDAVHRERRRKAQEFSRKVDEILGDQPTAKEQVFAALKQFAAEQRVDDLVWTLTLALPREACGPLLDNLRIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPERLLVSTRASAPPRRPDEPPPRRASLLVGGLAGPGGARRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPADNAALKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFASDSDSLDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESFFQHRNIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMTAEPEPELDLESEPTPEPQPRSSLRASSMCRRSLRSQGLEAGLSCGPSECPEMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKMGTVSKSRASPPGPSPAVTTGPRTLSGVSWPSERLLPSPCYHPLCSGGLASPSSSESHPYASLDSSRAPSPQPGPGPICPDSPPSPDPTRPPSRRKLFTFSHPVRSRDTDRFLDVLSEQLGPRVTIVDDFLTPENDYEEMSFHDDQGSFVTNERSSASDCISSSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDAKPSSRSSDGSRGPAQALAKPLTQLSHPVPPPPPPPLPPPVPCAPPMLSRGLGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPAKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTSDLADLHGTISEIQDACQSISPSSEDKFAMVMSSFLETAQPALRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFAEFMSKFERALSDLQAGEGLRSSGMVSPLAW

Target ORF information:

RefSeq Version	NM_001145118.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Grid2 interacting protein (GRID2IP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145118.1

ORF Insert Sequence:

ATGGCCACCA CTGCCACGCC GGCCACGAAC CAGGGCTGGC CAGAGGACTT TGGCTTCCGG 
CTAGGTGGCT CTGGCCCCTG CTTCGTCCTG GAGGTGGCCA AGGGGAGCAG CGCGCATGCC 
GGAGGACTGC GGCCAGGAGA CCAGATCCTG GAGGTGGAGG GGCTGGCGGT GGGCGGTCTG 
AGCCGCGAGC GCCTCGTGCG CCTGGCACGG CGCTGCCCAC GTGTGCCGCC CAGTCTGGGC 
GTGCTCCCGG CTCCCGACGG TGGCCCCGGC CCAGGATCCG GCCCCGCGGC CCCGACCACA 
GTCTTGCGGG CCCCGCGGTG CGGCCGCGGC CTAGCTCTGG GCCGTGAGCT GCTTCGCCTG 
GCCGGCCGCA AGCGCCCGGA CGCGGTGCAC CGAGAGCGCA GGCGCAAGGC CCAAGAGTTC 
AGCCGCAAGG TGGATGAAAT CTTGGGGGAC CAGCCAACTG CCAAGGAGCA GGTGTTCGCT 
GCACTGAAGC AGTTTGCAGC TGAGCAGCGG GTGGATGATC TGGTGTGGAC TCTCACCCTG 
GCGCTGCCCC GAGAGGCCTG CGGGCCACTC CTGGACAACC TCAGGATCTT CATCCCCAAG 
AAGCACCGGG CGCGCTTCGA CGAGGTGGTG TCTCAGGGCC TCCTGGGCAA GCTGTGCCGC 
GCACGCCGGG CCCAGGGCGC GCAGCGACTG CGCCGGAGCC GCAGCGAGGA GCGGCCGGAG 
CGCCTCCTGG TGTCCACGCG CGCCAGCGCC CCGCCGCGCC GCCCCGATGA GCCGCCCCCG 
CGCAGGGCCT CCTTGCTGGT GGGCGGCCTC GCCGGCCCCG GGGGCGCGCG CAGGACTGTC 
CGAGTCTACA AAGGCAACAA GAGCTTCGGC TTCACACTTC GCGGCCACGG GCCTGTCTGG 
ATCGAGTCTG TCCTGCCTGG GAGCCCAGCT GACAATGCTG CCCTCAAGTC AGGTGACCGG 
ATCCTCTTCC TCAATGGACT GGACATGAGG AACTGCTCCC ACGACAAGGT GGTGTCCATG 
CTGCAGGGCA GTGGTGCCAT GCCCACGCTG GTGGTGGAGG AAGGGCTCGT CCCATTTGCC 
AGTGACTCCG ATTCTCTGGA CTCACCCAAC CCGTCGTCGG CGCTCACCTC CCTGCAGTGG 
GTGGCGGAGA TCCTGCCGTC CAGCATCCGG GTCCAAGGGA GGACCTTCAG CCAGCAGCTG 
GAGCACCTAC TCACACCTCC TGAGCGCTAT GGGGTCTGCC GGGCCCTCGA GAGCTTCTTC 
CAGCACAGGA ACATCGACAC CCTCATCGTT GACGTCTACC CTGTGCTGGA CACCCCTGCC 
AAGCAGGTCC TGTGGCAGTT CATCTACCAG CTGCTGACCT ATGAGGAGCA GGAGCTCTGT 
CAGGAGAAAA TCGCATGCTT CCTGGGCTAC ACGGCCATGA CAGCAGAGCC GGAGCCTGAG 
CTGGACCTGG AGTCCGAGCC CACGCCTGAG CCCCAGCCGC GGAGCTCCCT GCGGGCTTCC 
TCCATGTGCC GCCGCAGCCT CCGGTCCCAG GGCCTGGAGG CCGGCCTCAG CTGCGGTCCC 
AGCGAGTGCC CTGAGATGCC TCTTCCCCTG ATCCCAGGCG AGCGCCAGGC AGGCGACGGC 
ACGTCCCTCC CTGAGACCCC CAACCCCAAG ATGATGTCAG CCGTCTATGC AGAGCTTGAG 
TCTCGACTGA ACAGCAGCTT CAAAGGGAAG ATGGGGACCG TGTCCAAATC CCGGGCTTCC 
CCTCCAGGCC CCAGCCCAGC AGTCACCACA GGGCCCAGGA CCCTGTCCGG CGTCTCATGG 
CCCAGCGAGC GACTCTTGCC CTCCCCCTGC TACCACCCGC TGTGTTCGGG GGGTCTGGCC 
TCCCCCAGCA GCTCTGAGTC CCACCCCTAC GCCAGCCTGG ACAGCAGCAG GGCACCCTCC 
CCACAGCCAG GCCCCGGGCC CATCTGCCCC GACAGCCCCC CAAGCCCGGA CCCCACCCGC 
CCGCCCAGCC GCAGGAAGCT CTTCACCTTC TCCCACCCTG TGCGAAGCCG CGATACTGAC 
CGCTTCCTGG ACGTGCTGAG CGAGCAGCTG GGCCCCCGGG TCACCATCGT GGATGATTTC 
CTGACCCCGG AGAACGACTA CGAGGAGATG AGCTTCCATG ATGACCAGGG CAGCTTCGTA 
ACCAATGAGC GGAGCAGCGC CAGCGACTGC ATCAGCAGCA GTGAAGAAGG CAGCTCCCTG 
ACCTACTCCT CCATCTCTGA CCACATCCCC CCACCCCCGC TCAGCCCCCC ACCACCGCCA 
CCCCTGCCTT TCCATGACGC TAAGCCCAGC TCCCGCAGCT CTGATGGTTC CCGGGGCCCT 
GCTCAGGCGC TGGCCAAGCC CCTCACCCAA CTCAGCCACC CAGTCCCTCC ACCACCCCCA 
CCGCCCCTGC CCCCACCCGT GCCCTGTGCA CCCCCCATGC TGTCCCGGGG CCTGGGCCAC 
CGGCGCAGTG AGACCAGCCA CATGAGCGTC AAGCGCTTGC GGTGGGAACA GGTGGAGAAC 
TCAGAAGGCA CCATCTGGGG TCAGCTCGGG GAAGACTCTG ACTACGATAA GCTGAGTGAC 
ATGGTGAAAT ACCTCGACCT GGAGCTCCAC TTCGGCACCC AGAAACCTGC TAAACCGGTG 
CCGGGGCCGG AGCCCTTCCG GAAGAAGGAG GTGGTGGAGA TCCTGTCCCA TAAGAAGGCC 
TACAACACCT CCATCCTCTT GGCACACCTG AAGCTGAGCC CCGCGGAGCT GCGCCAGGTG 
CTGATGAGCA TGGAGCCCCG GCGCCTGGAG CCCGCACATC TCGCGCAGCT GCTGCTCTTC 
GCGCCCGACG CCGACGAGGA GCAGCGCTAC CAGGCCTTCC GCGAGGCGCC CGGCCGCCTC 
AGCGAGCCGG ACCAGTTCGT CCTGCAGATG CTGTCAGTTC CCGAATACAA GACACGCCTG 
CGCAGCCTCC ACTTCCAGGC CACCCTCCAG GAGAAGACAG AGGAGATCCG AGGCAGCCTT 
GAATGCTTGC GCCAGGCCTC CCTGGAGCTC AAAAACAGTC GGAAGCTCGC CAAGATCCTG 
GAGTTTGTGT TGGCCATGGG CAACTATCTC AACGATGGAC AGCCCAAAAC CAACAAGACT 
ACGGGCTTCA AGATCAACTT TCTGACAGAG CTGAACTCCA CCAAGACAGT GGATGGGAAG 
TCCACCTTCC TGCACATCCT TGCCAAATCG CTGAGCCAGC ACTTCCCTGA ACTCCTGGGC 
TTTGCTCAGG ACCTGCCCAC CGTGCCCCTG GCTGCCAAAG TGAACCAACG GGCCCTGACC 
AGTGACCTGG CTGACCTCCA TGGCACTATC AGCGAGATAC AGGATGCCTG CCAGAGCATT 
TCCCCCTCTA GCGAGGACAA GTTTGCAATG GTCATGTCGT CCTTCCTGGA GACGGCCCAG 
CCAGCACTTC GGGCGCTCGA CGGGCTGCAG CGCGAGGCCA TGGAGGAGCT GGGCAAGGCG 
CTGGCCTTCT TTGGGGAGGA TTCCAAGGCC ACCACCTCTG AGGCTTTCTT CGGCATCTTT 
GCAGAGTTCA TGAGCAAATT CGAGCGAGCG CTGAGTGACC TGCAGGCCGG GGAGGGCCTG 
CGCAGCTCCG GGATGGTTTC ACCCCTGGCC TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts.
Gut64(11)1774-82(2015 Nov)
Ek WE,Reznichenko A,Ripke S,Niesler B,Zucchelli M,Rivera NV,Schmidt PT,Pedersen NL,Magnusson P,Talley NJ,Holliday EG,Houghton L,Gazouli M,Karamanolis G,Rappold G,Burwinkel B,Surowy H,Rafter J,Assadi G,Li L,Papadaki E,Gambaccini D,Marchi S,Colucci R,Blandizzi C,Barbaro R,Karling P,Walter S,Ohlsson B,Tornblom H,Bresso F,Andreasson A,Dlugosz A,Simren M,Agreus L,Lindberg G,Boeckxstaens G,Bellini M,Stanghellini V,Barbara G,Daly MJ,Camilleri M,Wouters MM,D'Amato M

Binding of glutamate receptor delta2 to its scaffold protein, Delphilin, is regulated by PKA.
Biochemical and biophysical research communications350(3)748-52(2006 Nov)
Sonoda T,Mochizuki C,Yamashita T,Watanabe-Kaneko K,Miyagi Y,Shigeri Y,Yazama F,Okuda K,Kawamoto S

Characterization of the delta2 glutamate receptor-binding protein delphilin: Splicing variants with differential palmitoylation and an additional PDZ domain.
The Journal of biological chemistry281(35)25577-87(2006 Sep)
Matsuda K,Matsuda S,Gladding CM,Yuzaki M

Identification and characterization of human GRID2IP gene and rat Grid2ip gene in silico.
International journal of molecular medicine12(6)1015-9(2003 Dec)
Katoh M,Katoh M

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GRID2IP cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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