XRCC6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	XRCC6
Entrez Gene ID	2547
Full Name	X-ray repair cross complementing 6
Synonyms	CTC75,CTCBF,G22P1,KU70,ML8,TLAA
General protein information	Preferred Names X-ray repair cross complementing 6 Names X-ray repair cross-complementing protein 6 5'-dRP lyase Ku70 5'-deoxyribose-5-phosphate lyase Ku70 70 kDa subunit of Ku antigen ATP-dependent DNA helicase 2 subunit 1 ATP-dependent DNA helicase II, 70 kDa subunit CTC box binding factor 75 kDa subunit DNA repair protein XRCC6 Ku autoantigen p70 subunit Ku autoantigen, 70kDa X-ray repair complementing defective repair in Chinese hamster cells 6 lupus Ku autoantigen protein p70 thyroid autoantigen 70kD (Ku antigen) thyroid autoantigen 70kDa (Ku antigen) thyroid-lupus autoantigen p70
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q13.2
Summary	The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008].
Disorder MIM:	152690

mRNA and Protein(s)

mRNA	Protein	Name
NM_001288976.1	NP_001275905.1	X-ray repair cross-complementing protein 6 isoform 1
NM_001469.5	NP_001460.1	X-ray repair cross-complementing protein 6 isoform 1
NM_001288976.2	NP_001275905.1	X-ray repair cross-complementing protein 6 isoform 1
NM_001288978.1	NP_001275907.1	X-ray repair cross-complementing protein 6 isoform 3
NM_001469.4	NP_001460.1	X-ray repair cross-complementing protein 6 isoform 1
NM_001288977.1	NP_001275906.1	X-ray repair cross-complementing protein 6 isoform 2
NM_001288977.2	NP_001275906.1	X-ray repair cross-complementing protein 6 isoform 2

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	XRCC6	XP_001105684.1
Gallus gallus (chicken)	XRCC6	NP_990258.1
Danio rerio (zebrafish)	LOC100536337	XP_003199637.1
Neurospora crassa	NCU08290	XP_962503.2
Canis lupus familiaris (dog)	XRCC6	XP_005625882.1
Mus musculus (house mouse)	Xrcc6	NP_034377.2
Xenopus tropicalis (tropical clawed frog)	xrcc6	NP_001005700.1
Danio rerio (zebrafish)	xrcc6	NP_956198.1
Arabidopsis thaliana (thale cress)	KU70	NP_564012.1
Oryza sativa (rice)	Os07g0184900	NP_001059061.1
Kluyveromyces lactis	KLLA0C06226g	XP_452475.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002690	XP_312232.5
Schizosaccharomyces pombe (fission yeast)	pku70	NP_588445.1
Bos taurus (cattle)	XRCC6	NP_001179175.1
Rattus norvegicus (Norway rat)	Xrcc6	NP_620780.2
Magnaporthe oryzae (rice blast fungus)	MGG_01512	XP_003714485.1
Homo sapiens (human)	XRCC6	NP_001460.1
Pan troglodytes (chimpanzee)	XRCC6	XP_521301.3
Drosophila melanogaster (fruit fly)	Irbp	NP_536773.1
Caenorhabditis elegans (roundworm)	cku-70	NP_499438.2
Saccharomyces cerevisiae (baker's yeast)	YKU70	NP_014011.1

Gene Ontology
Bibliography

Related articles in PubMed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.
Hubel P, Urban C, Bergant V, Schneider WM, Knauer B, Stukalov A, Scaturro P, Mann A, Brunotte L, Hoffmann HH, Schoggins JW, Schwemmle M, Mann M, Rice CM, Pichlmair A
Nature immunology20(4)493-502(2019 04)

The deoxyribose phosphate lyase of DNA polymerase β suppresses a processive DNA synthesis to prevent trinucleotide repeat instability.
Lai Y, Weizmann Y, Liu Y
Nucleic acids research46(17)8940-8952(2018 09)

Ku70 N-terminal lysines acetylation/deacetylation is required for radiation-induced DNA-double strand breaks repair.
Al Emam A, Arbon D, Jeeves M, Kysela B
Neoplasma65(5)708-719(2018 Sep)

Protective effects of SIRT6 against lipopolysaccharide (LPS) are mediated by deacetylation of Ku70.
Zhang L, Bai L, Ren Q, Sun G, Si Y
Molecular immunology101312-318(2018 09)

KU70 Inhibition Impairs Both Non-Homologous End Joining and Homologous Recombination DNA Damage Repair Through SHP-1 Induced Dephosphorylation of SIRT1 in T-Cell Acute Lymphoblastic Leukemia (T-ALL) [corrected].
Yu W, Li L, Wang G, Zhang W, Xu J, Liang A
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology49(6)2111-2123(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following XRCC6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XRCC6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15909	NM_001288978.1 Latest version!	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu16003	NM_001288977.2 Latest version!	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu27504	NM_001288976.2 Latest version!	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
OHu27504	NM_001469.5 Latest version!	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
View Old Accession Versions >>
OHu27504	NM_001288976.1	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
OHu27504	NM_001469.4	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
OHu16003	NM_001288977.1	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

XRCC6 ( NM_001288978.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275907.1 Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 4, mRNA.

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CloneID	OHu15909
Clone ID Related Accession (Same CDS sequence)	NM_001288978.1
Accession Version	NM_001288978.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573747200000
Organism	Homo sapiens(human)
Product	X-ray repair cross-complementing protein 6 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z83840.7, AK293439.1, AK304580.1, BI222708.1 and BU751953.1. On Jan 10, 2014 this sequence version replaced XM_005261489.1. Transcript Variant: This variant (4) lacks an alternate in-frame exon and uses a downstream translation start, compared to variant 1. The encoded protein (isoform 3) has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304580.1, AK293439.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAAGC AGAGGAAGAA CAAGAAGAGA ACCTTGAAGC AAGTGTGTAT CCAAAGTGTG 
TACATCAGTA AGATCATAAG CAGTGATCGA GATCTCTTGG CTGTGGTGTT CTATGGTACC 
GAGAAAGACA AAAATTCAGT GAATTTTAAA AATATTTACG TCTTACAGGA GCTGGATAAT 
CCAGGTGCAA AACGAATTCT AGAGCTTGAC CAGTTTAAGG GGCAGCAGGG ACAAAAACGT 
TTCCAAGACA TGATGGGCCA CGGATCTGAC TACTCACTCA GTGAAGTGCT GTGGGTCTGT 
GCCAACCTCT TTAGTGATGT CCAATTCAAG ATGAGTCATA AGAGGATCAT GCTGTTCACC 
AATGAAGACA ACCCCCATGG CAATGACAGT GCCAAAGCCA GCCGGGCCAG GACCAAAGCC 
GGTGATCTCC GAGATACAGG CATCTTCCTT GACTTGATGC ACCTGAAGAA ACCTGGGGGC 
TTTGACATAT CCTTGTTCTA CAGAGATATC ATCAGCATAG CAGAGGATGA GGACCTCAGG 
GTTCACTTTG AGGAATCCAG CAAGCTAGAA GACCTGTTGC GGAAGGTTCG CGCCAAGGAG 
ACCAGGAAGC GAGCACTCAG CAGGTTAAAG CTGAAGCTCA ACAAAGATAT AGTGATCTCT 
GTGGGCATTT ATAATCTGGT CCAGAAGGCT CTCAAGCCTC CTCCAATAAA GCTCTATCGG 
GAAACAAATG AACCAGTGAA AACCAAGACC CGGACCTTTA ATACAAGTAC AGGCGGTTTG 
CTTCTGCCTA GCGATACCAA GAGGTCTCAG ATCTATGGGA GTCGTCAGAT TATACTGGAG 
AAAGAGGAAA CAGAAGAGCT AAAACGGTTT GATGATCCAG GTTTGATGCT CATGGGTTTC 
AAGCCGTTGG TACTGCTGAA GAAACACCAT TACCTGAGGC CCTCCCTGTT CGTGTACCCA 
GAGGAGTCGC TGGTGATTGG GAGCTCAACC CTGTTCAGTG CTCTGCTCAT CAAGTGTCTG 
GAGAAGGAGG TTGCAGCATT GTGCAGATAC ACACCCCGCA GGAACATCCC TCCTTATTTT 
GTGGCTTTGG TGCCACAGGA AGAAGAGTTG GATGACCAGA AAATTCAGGT GACTCCTCCA 
GGCTTCCAGC TGGTCTTTTT ACCCTTTGCT GATGATAAAA GGAAGATGCC CTTTACTGAA 
AAAATCATGG CAACTCCAGA GCAGGTGGGC AAGATGAAGG CTATCGTTGA GAAGCTTCGC 
TTCACATACA GAAGTGACAG CTTTGAGAAC CCCGTGCTGC AGCAGCACTT CAGGAACCTG 
GAGGCCTTGG CCTTGGATTT GATGGAGCCG GAACAAGCAG TGGACCTGAC ATTGCCCAAG 
GTTGAAGCAA TGAATAAAAG ACTGGGCTCC TTGGTGGATG AGTTTAAGGA GCTTGTTTAC 
CCACCAGATT ACAATCCTGA AGGGAAAGTT ACCAAGAGAA AACACGATAA TGAAGGTTCT 
GGAAGCAAAA GGCCCAAGGT GGAGTATTCA GAAGAGGAGC TGAAGACCCA CATCAGCAAG 
GGTACGCTGG GCAAGTTCAC TGTGCCCATG CTGAAAGAGG CCTGCCGGGC TTACGGGCTG 
AAGAGTGGGC TGAAGAAGCA GGAGCTGCTG GAAGCCCTCA CCAAGCACTT CCAGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275907.1
CDS	236..1915
Translation	MKKQRKNKKRTLKQVCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD

Target ORF information:

RefSeq Version	NM_001288978.1
Organism	Homo sapiens(human)
Definition	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288978.1

ORF Insert Sequence:

ATGAAGAAGC AGAGGAAGAA CAAGAAGAGA ACCTTGAAGC AAGTGTGTAT CCAAAGTGTG 
TACATCAGTA AGATCATAAG CAGTGATCGA GATCTCTTGG CTGTGGTGTT CTATGGTACC 
GAGAAAGACA AAAATTCAGT GAATTTTAAA AATATTTACG TCTTACAGGA GCTGGATAAT 
CCAGGTGCAA AACGAATTCT AGAGCTTGAC CAGTTTAAGG GGCAGCAGGG ACAAAAACGT 
TTCCAAGACA TGATGGGCCA CGGATCTGAC TACTCACTCA GTGAAGTGCT GTGGGTCTGT 
GCCAACCTCT TTAGTGATGT CCAATTCAAG ATGAGTCATA AGAGGATCAT GCTGTTCACC 
AATGAAGACA ACCCCCATGG CAATGACAGT GCCAAAGCCA GCCGGGCCAG GACCAAAGCC 
GGTGATCTCC GAGATACAGG CATCTTCCTT GACTTGATGC ACCTGAAGAA ACCTGGGGGC 
TTTGACATAT CCTTGTTCTA CAGAGATATC ATCAGCATAG CAGAGGATGA GGACCTCAGG 
GTTCACTTTG AGGAATCCAG CAAGCTAGAA GACCTGTTGC GGAAGGTTCG CGCCAAGGAG 
ACCAGGAAGC GAGCACTCAG CAGGTTAAAG CTGAAGCTCA ACAAAGATAT AGTGATCTCT 
GTGGGCATTT ATAATCTGGT CCAGAAGGCT CTCAAGCCTC CTCCAATAAA GCTCTATCGG 
GAAACAAATG AACCAGTGAA AACCAAGACC CGGACCTTTA ATACAAGTAC AGGCGGTTTG 
CTTCTGCCTA GCGATACCAA GAGGTCTCAG ATCTATGGGA GTCGTCAGAT TATACTGGAG 
AAAGAGGAAA CAGAAGAGCT AAAACGGTTT GATGATCCAG GTTTGATGCT CATGGGTTTC 
AAGCCGTTGG TACTGCTGAA GAAACACCAT TACCTGAGGC CCTCCCTGTT CGTGTACCCA 
GAGGAGTCGC TGGTGATTGG GAGCTCAACC CTGTTCAGTG CTCTGCTCAT CAAGTGTCTG 
GAGAAGGAGG TTGCAGCATT GTGCAGATAC ACACCCCGCA GGAACATCCC TCCTTATTTT 
GTGGCTTTGG TGCCACAGGA AGAAGAGTTG GATGACCAGA AAATTCAGGT GACTCCTCCA 
GGCTTCCAGC TGGTCTTTTT ACCCTTTGCT GATGATAAAA GGAAGATGCC CTTTACTGAA 
AAAATCATGG CAACTCCAGA GCAGGTGGGC AAGATGAAGG CTATCGTTGA GAAGCTTCGC 
TTCACATACA GAAGTGACAG CTTTGAGAAC CCCGTGCTGC AGCAGCACTT CAGGAACCTG 
GAGGCCTTGG CCTTGGATTT GATGGAGCCG GAACAAGCAG TGGACCTGAC ATTGCCCAAG 
GTTGAAGCAA TGAATAAAAG ACTGGGCTCC TTGGTGGATG AGTTTAAGGA GCTTGTTTAC 
CCACCAGATT ACAATCCTGA AGGGAAAGTT ACCAAGAGAA AACACGATAA TGAAGGTTCT 
GGAAGCAAAA GGCCCAAGGT GGAGTATTCA GAAGAGGAGC TGAAGACCCA CATCAGCAAG 
GGTACGCTGG GCAAGTTCAC TGTGCCCATG CTGAAAGAGG CCTGCCGGGC TTACGGGCTG 
AAGAGTGGGC TGAAGAAGCA GGAGCTGCTG GAAGCCCTCA CCAAGCACTT CCAGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRCC6 ( NM_001288977.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275906.1 Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16003
Clone ID Related Accession (Same CDS sequence)	NM_001288977.1 , NM_001288977.2
Accession Version	NM_001288977.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1549036800000
Organism	Homo sapiens(human)
Product	X-ray repair cross-complementing protein 6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z83840.7, AK055786.1, BU584415.1, BQ217843.1 and BU751953.1. On Jan 10, 2014 this sequence version replaced XM_005261488.1. Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region. The encoded protein (isoform 2) is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK055786.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGGAGCT GGATAATCCA GGTGCAAAAC GAATTCTAGA GCTTGACCAG 
TTTAAGGGGC AGCAGGGACA AAAACGTTTC CAAGACATGA TGGGCCACGG ATCTGACTAC 
TCACTCAGTG AAGTGCTGTG GGTCTGTGCC AACCTCTTTA GTGATGTCCA ATTCAAGATG 
AGTCATAAGA GGATCATGCT GTTCACCAAT GAAGACAACC CCCATGGCAA TGACAGTGCC 
AAAGCCAGCC GGGCCAGGAC CAAAGCCGGT GATCTCCGAG ATACAGGCAT CTTCCTTGAC 
TTGATGCACC TGAAGAAACC TGGGGGCTTT GACATATCCT TGTTCTACAG AGATATCATC 
AGCATAGCAG AGGATGAGGA CCTCAGGGTT CACTTTGAGG AATCCAGCAA GCTAGAAGAC 
CTGTTGCGGA AGGTTCGCGC CAAGGAGACC AGGAAGCGAG CACTCAGCAG GTTAAAGCTG 
AAGCTCAACA AAGATATAGT GATCTCTGTG GGCATTTATA ATCTGGTCCA GAAGGCTCTC 
AAGCCTCCTC CAATAAAGCT CTATCGGGAA ACAAATGAAC CAGTGAAAAC CAAGACCCGG 
ACCTTTAATA CAAGTACAGG CGGTTTGCTT CTGCCTAGCG ATACCAAGAG GTCTCAGATC 
TATGGGAGTC GTCAGATTAT ACTGGAGAAA GAGGAAACAG AAGAGCTAAA ACGGTTTGAT 
GATCCAGGTT TGATGCTCAT GGGTTTCAAG CCGTTGGTAC TGCTGAAGAA ACACCATTAC 
CTGAGGCCCT CCCTGTTCGT GTACCCAGAG GAGTCGCTGG TGATTGGGAG CTCAACCCTG 
TTCAGTGCTC TGCTCATCAA GTGTCTGGAG AAGGAGGTTG CAGCATTGTG CAGATACACA 
CCCCGCAGGA ACATCCCTCC TTATTTTGTG GCTTTGGTGC CACAGGAAGA AGAGTTGGAT 
GACCAGAAAA TTCAGGTGAC TCCTCCAGGC TTCCAGCTGG TCTTTTTACC CTTTGCTGAT 
GATAAAAGGA AGATGCCCTT TACTGAAAAA ATCATGGCAA CTCCAGAGCA GGTGGGCAAG 
ATGAAGGCTA TCGTTGAGAA GCTTCGCTTC ACATACAGAA GTGACAGCTT TGAGAACCCC 
GTGCTGCAGC AGCACTTCAG GAACCTGGAG GCCTTGGCCT TGGATTTGAT GGAGCCGGAA 
CAAGCAGTGG ACCTGACATT GCCCAAGGTT GAAGCAATGA ATAAAAGACT GGGCTCCTTG 
GTGGATGAGT TTAAGGAGCT TGTTTACCCA CCAGATTACA ATCCTGAAGG GAAAGTTACC 
AAGAGAAAAC ACGATAATGA AGGTTCTGGA AGCAAAAGGC CCAAGGTGGA GTATTCAGAA 
GAGGAGCTGA AGACCCACAT CAGCAAGGGT ACGCTGGGCA AGTTCACTGT GCCCATGCTG 
AAAGAGGCCT GCCGGGCTTA CGGGCTGAAG AGTGGGCTGA AGAAGCAGGA GCTGCTGGAA 
GCCCTCACCA AGCACTTCCA GGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275906.1
CDS	199..1905
Translation	MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD

Target ORF information:

RefSeq Version	NM_001288977.1
Organism	Homo sapiens(human)
Definition	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288977.1

ORF Insert Sequence:

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGGAGCT GGATAATCCA GGTGCAAAAC GAATTCTAGA GCTTGACCAG 
TTTAAGGGGC AGCAGGGACA AAAACGTTTC CAAGACATGA TGGGCCACGG ATCTGACTAC 
TCACTCAGTG AAGTGCTGTG GGTCTGTGCC AACCTCTTTA GTGATGTCCA ATTCAAGATG 
AGTCATAAGA GGATCATGCT GTTCACCAAT GAAGACAACC CCCATGGCAA TGACAGTGCC 
AAAGCCAGCC GGGCCAGGAC CAAAGCCGGT GATCTCCGAG ATACAGGCAT CTTCCTTGAC 
TTGATGCACC TGAAGAAACC TGGGGGCTTT GACATATCCT TGTTCTACAG AGATATCATC 
AGCATAGCAG AGGATGAGGA CCTCAGGGTT CACTTTGAGG AATCCAGCAA GCTAGAAGAC 
CTGTTGCGGA AGGTTCGCGC CAAGGAGACC AGGAAGCGAG CACTCAGCAG GTTAAAGCTG 
AAGCTCAACA AAGATATAGT GATCTCTGTG GGCATTTATA ATCTGGTCCA GAAGGCTCTC 
AAGCCTCCTC CAATAAAGCT CTATCGGGAA ACAAATGAAC CAGTGAAAAC CAAGACCCGG 
ACCTTTAATA CAAGTACAGG CGGTTTGCTT CTGCCTAGCG ATACCAAGAG GTCTCAGATC 
TATGGGAGTC GTCAGATTAT ACTGGAGAAA GAGGAAACAG AAGAGCTAAA ACGGTTTGAT 
GATCCAGGTT TGATGCTCAT GGGTTTCAAG CCGTTGGTAC TGCTGAAGAA ACACCATTAC 
CTGAGGCCCT CCCTGTTCGT GTACCCAGAG GAGTCGCTGG TGATTGGGAG CTCAACCCTG 
TTCAGTGCTC TGCTCATCAA GTGTCTGGAG AAGGAGGTTG CAGCATTGTG CAGATACACA 
CCCCGCAGGA ACATCCCTCC TTATTTTGTG GCTTTGGTGC CACAGGAAGA AGAGTTGGAT 
GACCAGAAAA TTCAGGTGAC TCCTCCAGGC TTCCAGCTGG TCTTTTTACC CTTTGCTGAT 
GATAAAAGGA AGATGCCCTT TACTGAAAAA ATCATGGCAA CTCCAGAGCA GGTGGGCAAG 
ATGAAGGCTA TCGTTGAGAA GCTTCGCTTC ACATACAGAA GTGACAGCTT TGAGAACCCC 
GTGCTGCAGC AGCACTTCAG GAACCTGGAG GCCTTGGCCT TGGATTTGAT GGAGCCGGAA 
CAAGCAGTGG ACCTGACATT GCCCAAGGTT GAAGCAATGA ATAAAAGACT GGGCTCCTTG 
GTGGATGAGT TTAAGGAGCT TGTTTACCCA CCAGATTACA ATCCTGAAGG GAAAGTTACC 
AAGAGAAAAC ACGATAATGA AGGTTCTGGA AGCAAAAGGC CCAAGGTGGA GTATTCAGAA 
GAGGAGCTGA AGACCCACAT CAGCAAGGGT ACGCTGGGCA AGTTCACTGT GCCCATGCTG 
AAAGAGGCCT GCCGGGCTTA CGGGCTGAAG AGTGGGCTGA AGAAGCAGGA GCTGCTGGAA 
GCCCTCACCA AGCACTTCCA GGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRCC6 ( NM_001288977.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275906.1 Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16003
Clone ID Related Accession (Same CDS sequence)	NM_001288977.1 , NM_001288977.2
Accession Version	NM_001288977.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571932800000
Organism	Homo sapiens(human)
Product	X-ray repair cross-complementing protein 6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK055786.1, BU584415.1, BQ217843.1 and BU751953.1. On Jun 2, 2019 this sequence version replaced NM_001288977.1. Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region. The encoded protein (isoform 2) is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK055786.1, SRR7410570.465423.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGGAGCT GGATAATCCA GGTGCAAAAC GAATTCTAGA GCTTGACCAG 
TTTAAGGGGC AGCAGGGACA AAAACGTTTC CAAGACATGA TGGGCCACGG ATCTGACTAC 
TCACTCAGTG AAGTGCTGTG GGTCTGTGCC AACCTCTTTA GTGATGTCCA ATTCAAGATG 
AGTCATAAGA GGATCATGCT GTTCACCAAT GAAGACAACC CCCATGGCAA TGACAGTGCC 
AAAGCCAGCC GGGCCAGGAC CAAAGCCGGT GATCTCCGAG ATACAGGCAT CTTCCTTGAC 
TTGATGCACC TGAAGAAACC TGGGGGCTTT GACATATCCT TGTTCTACAG AGATATCATC 
AGCATAGCAG AGGATGAGGA CCTCAGGGTT CACTTTGAGG AATCCAGCAA GCTAGAAGAC 
CTGTTGCGGA AGGTTCGCGC CAAGGAGACC AGGAAGCGAG CACTCAGCAG GTTAAAGCTG 
AAGCTCAACA AAGATATAGT GATCTCTGTG GGCATTTATA ATCTGGTCCA GAAGGCTCTC 
AAGCCTCCTC CAATAAAGCT CTATCGGGAA ACAAATGAAC CAGTGAAAAC CAAGACCCGG 
ACCTTTAATA CAAGTACAGG CGGTTTGCTT CTGCCTAGCG ATACCAAGAG GTCTCAGATC 
TATGGGAGTC GTCAGATTAT ACTGGAGAAA GAGGAAACAG AAGAGCTAAA ACGGTTTGAT 
GATCCAGGTT TGATGCTCAT GGGTTTCAAG CCGTTGGTAC TGCTGAAGAA ACACCATTAC 
CTGAGGCCCT CCCTGTTCGT GTACCCAGAG GAGTCGCTGG TGATTGGGAG CTCAACCCTG 
TTCAGTGCTC TGCTCATCAA GTGTCTGGAG AAGGAGGTTG CAGCATTGTG CAGATACACA 
CCCCGCAGGA ACATCCCTCC TTATTTTGTG GCTTTGGTGC CACAGGAAGA AGAGTTGGAT 
GACCAGAAAA TTCAGGTGAC TCCTCCAGGC TTCCAGCTGG TCTTTTTACC CTTTGCTGAT 
GATAAAAGGA AGATGCCCTT TACTGAAAAA ATCATGGCAA CTCCAGAGCA GGTGGGCAAG 
ATGAAGGCTA TCGTTGAGAA GCTTCGCTTC ACATACAGAA GTGACAGCTT TGAGAACCCC 
GTGCTGCAGC AGCACTTCAG GAACCTGGAG GCCTTGGCCT TGGATTTGAT GGAGCCGGAA 
CAAGCAGTGG ACCTGACATT GCCCAAGGTT GAAGCAATGA ATAAAAGACT GGGCTCCTTG 
GTGGATGAGT TTAAGGAGCT TGTTTACCCA CCAGATTACA ATCCTGAAGG GAAAGTTACC 
AAGAGAAAAC ACGATAATGA AGGTTCTGGA AGCAAAAGGC CCAAGGTGGA GTATTCAGAA 
GAGGAGCTGA AGACCCACAT CAGCAAGGGT ACGCTGGGCA AGTTCACTGT GCCCATGCTG 
AAAGAGGCCT GCCGGGCTTA CGGGCTGAAG AGTGGGCTGA AGAAGCAGGA GCTGCTGGAA 
GCCCTCACCA AGCACTTCCA GGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275906.1
CDS	67..1773
Translation	MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD

Target ORF information:

RefSeq Version	NM_001288977.2
Organism	Homo sapiens(human)
Definition	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288977.2

ORF Insert Sequence:

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGGAGCT GGATAATCCA GGTGCAAAAC GAATTCTAGA GCTTGACCAG 
TTTAAGGGGC AGCAGGGACA AAAACGTTTC CAAGACATGA TGGGCCACGG ATCTGACTAC 
TCACTCAGTG AAGTGCTGTG GGTCTGTGCC AACCTCTTTA GTGATGTCCA ATTCAAGATG 
AGTCATAAGA GGATCATGCT GTTCACCAAT GAAGACAACC CCCATGGCAA TGACAGTGCC 
AAAGCCAGCC GGGCCAGGAC CAAAGCCGGT GATCTCCGAG ATACAGGCAT CTTCCTTGAC 
TTGATGCACC TGAAGAAACC TGGGGGCTTT GACATATCCT TGTTCTACAG AGATATCATC 
AGCATAGCAG AGGATGAGGA CCTCAGGGTT CACTTTGAGG AATCCAGCAA GCTAGAAGAC 
CTGTTGCGGA AGGTTCGCGC CAAGGAGACC AGGAAGCGAG CACTCAGCAG GTTAAAGCTG 
AAGCTCAACA AAGATATAGT GATCTCTGTG GGCATTTATA ATCTGGTCCA GAAGGCTCTC 
AAGCCTCCTC CAATAAAGCT CTATCGGGAA ACAAATGAAC CAGTGAAAAC CAAGACCCGG 
ACCTTTAATA CAAGTACAGG CGGTTTGCTT CTGCCTAGCG ATACCAAGAG GTCTCAGATC 
TATGGGAGTC GTCAGATTAT ACTGGAGAAA GAGGAAACAG AAGAGCTAAA ACGGTTTGAT 
GATCCAGGTT TGATGCTCAT GGGTTTCAAG CCGTTGGTAC TGCTGAAGAA ACACCATTAC 
CTGAGGCCCT CCCTGTTCGT GTACCCAGAG GAGTCGCTGG TGATTGGGAG CTCAACCCTG 
TTCAGTGCTC TGCTCATCAA GTGTCTGGAG AAGGAGGTTG CAGCATTGTG CAGATACACA 
CCCCGCAGGA ACATCCCTCC TTATTTTGTG GCTTTGGTGC CACAGGAAGA AGAGTTGGAT 
GACCAGAAAA TTCAGGTGAC TCCTCCAGGC TTCCAGCTGG TCTTTTTACC CTTTGCTGAT 
GATAAAAGGA AGATGCCCTT TACTGAAAAA ATCATGGCAA CTCCAGAGCA GGTGGGCAAG 
ATGAAGGCTA TCGTTGAGAA GCTTCGCTTC ACATACAGAA GTGACAGCTT TGAGAACCCC 
GTGCTGCAGC AGCACTTCAG GAACCTGGAG GCCTTGGCCT TGGATTTGAT GGAGCCGGAA 
CAAGCAGTGG ACCTGACATT GCCCAAGGTT GAAGCAATGA ATAAAAGACT GGGCTCCTTG 
GTGGATGAGT TTAAGGAGCT TGTTTACCCA CCAGATTACA ATCCTGAAGG GAAAGTTACC 
AAGAGAAAAC ACGATAATGA AGGTTCTGGA AGCAAAAGGC CCAAGGTGGA GTATTCAGAA 
GAGGAGCTGA AGACCCACAT CAGCAAGGGT ACGCTGGGCA AGTTCACTGT GCCCATGCTG 
AAAGAGGCCT GCCGGGCTTA CGGGCTGAAG AGTGGGCTGA AGAAGCAGGA GCTGCTGGAA 
GCCCTCACCA AGCACTTCCA GGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRCC6 ( NM_001288976.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275905.1 Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 2, mRNA.

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CloneID	OHu27504
Clone ID Related Accession (Same CDS sequence)	NM_001288976.1 , NM_001469.5 , NM_001288976.2 , NM_001469.4
Accession Version	NM_001288976.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1830bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550851200000
Organism	Homo sapiens(human)
Product	X-ray repair cross-complementing protein 6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA718140.1, DC383335.1, BU902323.1, DA647513.1, BC001583.1 and BU751953.1. On Jan 10, 2014 this sequence version replaced XM_005261487.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.295613.1, SRR1803615.73142.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGTGTAT CCAAAGTGTG TACATCAGTA AGATCATAAG CAGTGATCGA 
GATCTCTTGG CTGTGGTGTT CTATGGTACC GAGAAAGACA AAAATTCAGT GAATTTTAAA 
AATATTTACG TCTTACAGGA GCTGGATAAT CCAGGTGCAA AACGAATTCT AGAGCTTGAC 
CAGTTTAAGG GGCAGCAGGG ACAAAAACGT TTCCAAGACA TGATGGGCCA CGGATCTGAC 
TACTCACTCA GTGAAGTGCT GTGGGTCTGT GCCAACCTCT TTAGTGATGT CCAATTCAAG 
ATGAGTCATA AGAGGATCAT GCTGTTCACC AATGAAGACA ACCCCCATGG CAATGACAGT 
GCCAAAGCCA GCCGGGCCAG GACCAAAGCC GGTGATCTCC GAGATACAGG CATCTTCCTT 
GACTTGATGC ACCTGAAGAA ACCTGGGGGC TTTGACATAT CCTTGTTCTA CAGAGATATC 
ATCAGCATAG CAGAGGATGA GGACCTCAGG GTTCACTTTG AGGAATCCAG CAAGCTAGAA 
GACCTGTTGC GGAAGGTTCG CGCCAAGGAG ACCAGGAAGC GAGCACTCAG CAGGTTAAAG 
CTGAAGCTCA ACAAAGATAT AGTGATCTCT GTGGGCATTT ATAATCTGGT CCAGAAGGCT 
CTCAAGCCTC CTCCAATAAA GCTCTATCGG GAAACAAATG AACCAGTGAA AACCAAGACC 
CGGACCTTTA ATACAAGTAC AGGCGGTTTG CTTCTGCCTA GCGATACCAA GAGGTCTCAG 
ATCTATGGGA GTCGTCAGAT TATACTGGAG AAAGAGGAAA CAGAAGAGCT AAAACGGTTT 
GATGATCCAG GTTTGATGCT CATGGGTTTC AAGCCGTTGG TACTGCTGAA GAAACACCAT 
TACCTGAGGC CCTCCCTGTT CGTGTACCCA GAGGAGTCGC TGGTGATTGG GAGCTCAACC 
CTGTTCAGTG CTCTGCTCAT CAAGTGTCTG GAGAAGGAGG TTGCAGCATT GTGCAGATAC 
ACACCCCGCA GGAACATCCC TCCTTATTTT GTGGCTTTGG TGCCACAGGA AGAAGAGTTG 
GATGACCAGA AAATTCAGGT GACTCCTCCA GGCTTCCAGC TGGTCTTTTT ACCCTTTGCT 
GATGATAAAA GGAAGATGCC CTTTACTGAA AAAATCATGG CAACTCCAGA GCAGGTGGGC 
AAGATGAAGG CTATCGTTGA GAAGCTTCGC TTCACATACA GAAGTGACAG CTTTGAGAAC 
CCCGTGCTGC AGCAGCACTT CAGGAACCTG GAGGCCTTGG CCTTGGATTT GATGGAGCCG 
GAACAAGCAG TGGACCTGAC ATTGCCCAAG GTTGAAGCAA TGAATAAAAG ACTGGGCTCC 
TTGGTGGATG AGTTTAAGGA GCTTGTTTAC CCACCAGATT ACAATCCTGA AGGGAAAGTT 
ACCAAGAGAA AACACGATAA TGAAGGTTCT GGAAGCAAAA GGCCCAAGGT GGAGTATTCA 
GAAGAGGAGC TGAAGACCCA CATCAGCAAG GGTACGCTGG GCAAGTTCAC TGTGCCCATG 
CTGAAAGAGG CCTGCCGGGC TTACGGGCTG AAGAGTGGGC TGAAGAAGCA GGAGCTGCTG 
GAAGCCCTCA CCAAGCACTT CCAGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275905.1
CDS	85..1914
Translation	MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD

Target ORF information:

RefSeq Version	NM_001288976.1
Organism	Homo sapiens(human)
Definition	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288976.1

ORF Insert Sequence:

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGTGTAT CCAAAGTGTG TACATCAGTA AGATCATAAG CAGTGATCGA 
GATCTCTTGG CTGTGGTGTT CTATGGTACC GAGAAAGACA AAAATTCAGT GAATTTTAAA 
AATATTTACG TCTTACAGGA GCTGGATAAT CCAGGTGCAA AACGAATTCT AGAGCTTGAC 
CAGTTTAAGG GGCAGCAGGG ACAAAAACGT TTCCAAGACA TGATGGGCCA CGGATCTGAC 
TACTCACTCA GTGAAGTGCT GTGGGTCTGT GCCAACCTCT TTAGTGATGT CCAATTCAAG 
ATGAGTCATA AGAGGATCAT GCTGTTCACC AATGAAGACA ACCCCCATGG CAATGACAGT 
GCCAAAGCCA GCCGGGCCAG GACCAAAGCC GGTGATCTCC GAGATACAGG CATCTTCCTT 
GACTTGATGC ACCTGAAGAA ACCTGGGGGC TTTGACATAT CCTTGTTCTA CAGAGATATC 
ATCAGCATAG CAGAGGATGA GGACCTCAGG GTTCACTTTG AGGAATCCAG CAAGCTAGAA 
GACCTGTTGC GGAAGGTTCG CGCCAAGGAG ACCAGGAAGC GAGCACTCAG CAGGTTAAAG 
CTGAAGCTCA ACAAAGATAT AGTGATCTCT GTGGGCATTT ATAATCTGGT CCAGAAGGCT 
CTCAAGCCTC CTCCAATAAA GCTCTATCGG GAAACAAATG AACCAGTGAA AACCAAGACC 
CGGACCTTTA ATACAAGTAC AGGCGGTTTG CTTCTGCCTA GCGATACCAA GAGGTCTCAG 
ATCTATGGGA GTCGTCAGAT TATACTGGAG AAAGAGGAAA CAGAAGAGCT AAAACGGTTT 
GATGATCCAG GTTTGATGCT CATGGGTTTC AAGCCGTTGG TACTGCTGAA GAAACACCAT 
TACCTGAGGC CCTCCCTGTT CGTGTACCCA GAGGAGTCGC TGGTGATTGG GAGCTCAACC 
CTGTTCAGTG CTCTGCTCAT CAAGTGTCTG GAGAAGGAGG TTGCAGCATT GTGCAGATAC 
ACACCCCGCA GGAACATCCC TCCTTATTTT GTGGCTTTGG TGCCACAGGA AGAAGAGTTG 
GATGACCAGA AAATTCAGGT GACTCCTCCA GGCTTCCAGC TGGTCTTTTT ACCCTTTGCT 
GATGATAAAA GGAAGATGCC CTTTACTGAA AAAATCATGG CAACTCCAGA GCAGGTGGGC 
AAGATGAAGG CTATCGTTGA GAAGCTTCGC TTCACATACA GAAGTGACAG CTTTGAGAAC 
CCCGTGCTGC AGCAGCACTT CAGGAACCTG GAGGCCTTGG CCTTGGATTT GATGGAGCCG 
GAACAAGCAG TGGACCTGAC ATTGCCCAAG GTTGAAGCAA TGAATAAAAG ACTGGGCTCC 
TTGGTGGATG AGTTTAAGGA GCTTGTTTAC CCACCAGATT ACAATCCTGA AGGGAAAGTT 
ACCAAGAGAA AACACGATAA TGAAGGTTCT GGAAGCAAAA GGCCCAAGGT GGAGTATTCA 
GAAGAGGAGC TGAAGACCCA CATCAGCAAG GGTACGCTGG GCAAGTTCAC TGTGCCCATG 
CTGAAAGAGG CCTGCCGGGC TTACGGGCTG AAGAGTGGGC TGAAGAAGCA GGAGCTGCTG 
GAAGCCCTCA CCAAGCACTT CCAGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRCC6 ( NM_001469.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001460.1 Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 1, mRNA.

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CloneID	OHu27504
Clone ID Related Accession (Same CDS sequence)	NM_001288976.1 , NM_001469.5 , NM_001288976.2 , NM_001469.4
Accession Version	NM_001469.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1830bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571932800000
Organism	Homo sapiens(human)
Product	X-ray repair cross-complementing protein 6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK055786.1, BC018259.2 and BC012154.2. On Jun 2, 2019 this sequence version replaced NM_001469.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189658.98803.1, SRR1803614.280209.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGTGTAT CCAAAGTGTG TACATCAGTA AGATCATAAG CAGTGATCGA 
GATCTCTTGG CTGTGGTGTT CTATGGTACC GAGAAAGACA AAAATTCAGT GAATTTTAAA 
AATATTTACG TCTTACAGGA GCTGGATAAT CCAGGTGCAA AACGAATTCT AGAGCTTGAC 
CAGTTTAAGG GGCAGCAGGG ACAAAAACGT TTCCAAGACA TGATGGGCCA CGGATCTGAC 
TACTCACTCA GTGAAGTGCT GTGGGTCTGT GCCAACCTCT TTAGTGATGT CCAATTCAAG 
ATGAGTCATA AGAGGATCAT GCTGTTCACC AATGAAGACA ACCCCCATGG CAATGACAGT 
GCCAAAGCCA GCCGGGCCAG GACCAAAGCC GGTGATCTCC GAGATACAGG CATCTTCCTT 
GACTTGATGC ACCTGAAGAA ACCTGGGGGC TTTGACATAT CCTTGTTCTA CAGAGATATC 
ATCAGCATAG CAGAGGATGA GGACCTCAGG GTTCACTTTG AGGAATCCAG CAAGCTAGAA 
GACCTGTTGC GGAAGGTTCG CGCCAAGGAG ACCAGGAAGC GAGCACTCAG CAGGTTAAAG 
CTGAAGCTCA ACAAAGATAT AGTGATCTCT GTGGGCATTT ATAATCTGGT CCAGAAGGCT 
CTCAAGCCTC CTCCAATAAA GCTCTATCGG GAAACAAATG AACCAGTGAA AACCAAGACC 
CGGACCTTTA ATACAAGTAC AGGCGGTTTG CTTCTGCCTA GCGATACCAA GAGGTCTCAG 
ATCTATGGGA GTCGTCAGAT TATACTGGAG AAAGAGGAAA CAGAAGAGCT AAAACGGTTT 
GATGATCCAG GTTTGATGCT CATGGGTTTC AAGCCGTTGG TACTGCTGAA GAAACACCAT 
TACCTGAGGC CCTCCCTGTT CGTGTACCCA GAGGAGTCGC TGGTGATTGG GAGCTCAACC 
CTGTTCAGTG CTCTGCTCAT CAAGTGTCTG GAGAAGGAGG TTGCAGCATT GTGCAGATAC 
ACACCCCGCA GGAACATCCC TCCTTATTTT GTGGCTTTGG TGCCACAGGA AGAAGAGTTG 
GATGACCAGA AAATTCAGGT GACTCCTCCA GGCTTCCAGC TGGTCTTTTT ACCCTTTGCT 
GATGATAAAA GGAAGATGCC CTTTACTGAA AAAATCATGG CAACTCCAGA GCAGGTGGGC 
AAGATGAAGG CTATCGTTGA GAAGCTTCGC TTCACATACA GAAGTGACAG CTTTGAGAAC 
CCCGTGCTGC AGCAGCACTT CAGGAACCTG GAGGCCTTGG CCTTGGATTT GATGGAGCCG 
GAACAAGCAG TGGACCTGAC ATTGCCCAAG GTTGAAGCAA TGAATAAAAG ACTGGGCTCC 
TTGGTGGATG AGTTTAAGGA GCTTGTTTAC CCACCAGATT ACAATCCTGA AGGGAAAGTT 
ACCAAGAGAA AACACGATAA TGAAGGTTCT GGAAGCAAAA GGCCCAAGGT GGAGTATTCA 
GAAGAGGAGC TGAAGACCCA CATCAGCAAG GGTACGCTGG GCAAGTTCAC TGTGCCCATG 
CTGAAAGAGG CCTGCCGGGC TTACGGGCTG AAGAGTGGGC TGAAGAAGCA GGAGCTGCTG 
GAAGCCCTCA CCAAGCACTT CCAGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001460.1
CDS	67..1896
Translation	MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD

Target ORF information:

RefSeq Version	NM_001469.5
Organism	Homo sapiens(human)
Definition	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001469.5

ORF Insert Sequence:

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGTGTAT CCAAAGTGTG TACATCAGTA AGATCATAAG CAGTGATCGA 
GATCTCTTGG CTGTGGTGTT CTATGGTACC GAGAAAGACA AAAATTCAGT GAATTTTAAA 
AATATTTACG TCTTACAGGA GCTGGATAAT CCAGGTGCAA AACGAATTCT AGAGCTTGAC 
CAGTTTAAGG GGCAGCAGGG ACAAAAACGT TTCCAAGACA TGATGGGCCA CGGATCTGAC 
TACTCACTCA GTGAAGTGCT GTGGGTCTGT GCCAACCTCT TTAGTGATGT CCAATTCAAG 
ATGAGTCATA AGAGGATCAT GCTGTTCACC AATGAAGACA ACCCCCATGG CAATGACAGT 
GCCAAAGCCA GCCGGGCCAG GACCAAAGCC GGTGATCTCC GAGATACAGG CATCTTCCTT 
GACTTGATGC ACCTGAAGAA ACCTGGGGGC TTTGACATAT CCTTGTTCTA CAGAGATATC 
ATCAGCATAG CAGAGGATGA GGACCTCAGG GTTCACTTTG AGGAATCCAG CAAGCTAGAA 
GACCTGTTGC GGAAGGTTCG CGCCAAGGAG ACCAGGAAGC GAGCACTCAG CAGGTTAAAG 
CTGAAGCTCA ACAAAGATAT AGTGATCTCT GTGGGCATTT ATAATCTGGT CCAGAAGGCT 
CTCAAGCCTC CTCCAATAAA GCTCTATCGG GAAACAAATG AACCAGTGAA AACCAAGACC 
CGGACCTTTA ATACAAGTAC AGGCGGTTTG CTTCTGCCTA GCGATACCAA GAGGTCTCAG 
ATCTATGGGA GTCGTCAGAT TATACTGGAG AAAGAGGAAA CAGAAGAGCT AAAACGGTTT 
GATGATCCAG GTTTGATGCT CATGGGTTTC AAGCCGTTGG TACTGCTGAA GAAACACCAT 
TACCTGAGGC CCTCCCTGTT CGTGTACCCA GAGGAGTCGC TGGTGATTGG GAGCTCAACC 
CTGTTCAGTG CTCTGCTCAT CAAGTGTCTG GAGAAGGAGG TTGCAGCATT GTGCAGATAC 
ACACCCCGCA GGAACATCCC TCCTTATTTT GTGGCTTTGG TGCCACAGGA AGAAGAGTTG 
GATGACCAGA AAATTCAGGT GACTCCTCCA GGCTTCCAGC TGGTCTTTTT ACCCTTTGCT 
GATGATAAAA GGAAGATGCC CTTTACTGAA AAAATCATGG CAACTCCAGA GCAGGTGGGC 
AAGATGAAGG CTATCGTTGA GAAGCTTCGC TTCACATACA GAAGTGACAG CTTTGAGAAC 
CCCGTGCTGC AGCAGCACTT CAGGAACCTG GAGGCCTTGG CCTTGGATTT GATGGAGCCG 
GAACAAGCAG TGGACCTGAC ATTGCCCAAG GTTGAAGCAA TGAATAAAAG ACTGGGCTCC 
TTGGTGGATG AGTTTAAGGA GCTTGTTTAC CCACCAGATT ACAATCCTGA AGGGAAAGTT 
ACCAAGAGAA AACACGATAA TGAAGGTTCT GGAAGCAAAA GGCCCAAGGT GGAGTATTCA 
GAAGAGGAGC TGAAGACCCA CATCAGCAAG GGTACGCTGG GCAAGTTCAC TGTGCCCATG 
CTGAAAGAGG CCTGCCGGGC TTACGGGCTG AAGAGTGGGC TGAAGAAGCA GGAGCTGCTG 
GAAGCCCTCA CCAAGCACTT CCAGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRCC6 ( NM_001288976.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275905.1 Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 2, mRNA.

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CloneID	OHu27504
Clone ID Related Accession (Same CDS sequence)	NM_001288976.1 , NM_001469.5 , NM_001288976.2 , NM_001469.4
Accession Version	NM_001288976.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1830bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571932800000
Organism	Homo sapiens(human)
Product	X-ray repair cross-complementing protein 6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z83840.7, DA718140.1, DC383335.1, BU902323.1, DA647513.1 and BC001583.1. On Jun 2, 2019 this sequence version replaced NM_001288976.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.135787.1, SRR1803613.181322.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGTGTAT CCAAAGTGTG TACATCAGTA AGATCATAAG CAGTGATCGA 
GATCTCTTGG CTGTGGTGTT CTATGGTACC GAGAAAGACA AAAATTCAGT GAATTTTAAA 
AATATTTACG TCTTACAGGA GCTGGATAAT CCAGGTGCAA AACGAATTCT AGAGCTTGAC 
CAGTTTAAGG GGCAGCAGGG ACAAAAACGT TTCCAAGACA TGATGGGCCA CGGATCTGAC 
TACTCACTCA GTGAAGTGCT GTGGGTCTGT GCCAACCTCT TTAGTGATGT CCAATTCAAG 
ATGAGTCATA AGAGGATCAT GCTGTTCACC AATGAAGACA ACCCCCATGG CAATGACAGT 
GCCAAAGCCA GCCGGGCCAG GACCAAAGCC GGTGATCTCC GAGATACAGG CATCTTCCTT 
GACTTGATGC ACCTGAAGAA ACCTGGGGGC TTTGACATAT CCTTGTTCTA CAGAGATATC 
ATCAGCATAG CAGAGGATGA GGACCTCAGG GTTCACTTTG AGGAATCCAG CAAGCTAGAA 
GACCTGTTGC GGAAGGTTCG CGCCAAGGAG ACCAGGAAGC GAGCACTCAG CAGGTTAAAG 
CTGAAGCTCA ACAAAGATAT AGTGATCTCT GTGGGCATTT ATAATCTGGT CCAGAAGGCT 
CTCAAGCCTC CTCCAATAAA GCTCTATCGG GAAACAAATG AACCAGTGAA AACCAAGACC 
CGGACCTTTA ATACAAGTAC AGGCGGTTTG CTTCTGCCTA GCGATACCAA GAGGTCTCAG 
ATCTATGGGA GTCGTCAGAT TATACTGGAG AAAGAGGAAA CAGAAGAGCT AAAACGGTTT 
GATGATCCAG GTTTGATGCT CATGGGTTTC AAGCCGTTGG TACTGCTGAA GAAACACCAT 
TACCTGAGGC CCTCCCTGTT CGTGTACCCA GAGGAGTCGC TGGTGATTGG GAGCTCAACC 
CTGTTCAGTG CTCTGCTCAT CAAGTGTCTG GAGAAGGAGG TTGCAGCATT GTGCAGATAC 
ACACCCCGCA GGAACATCCC TCCTTATTTT GTGGCTTTGG TGCCACAGGA AGAAGAGTTG 
GATGACCAGA AAATTCAGGT GACTCCTCCA GGCTTCCAGC TGGTCTTTTT ACCCTTTGCT 
GATGATAAAA GGAAGATGCC CTTTACTGAA AAAATCATGG CAACTCCAGA GCAGGTGGGC 
AAGATGAAGG CTATCGTTGA GAAGCTTCGC TTCACATACA GAAGTGACAG CTTTGAGAAC 
CCCGTGCTGC AGCAGCACTT CAGGAACCTG GAGGCCTTGG CCTTGGATTT GATGGAGCCG 
GAACAAGCAG TGGACCTGAC ATTGCCCAAG GTTGAAGCAA TGAATAAAAG ACTGGGCTCC 
TTGGTGGATG AGTTTAAGGA GCTTGTTTAC CCACCAGATT ACAATCCTGA AGGGAAAGTT 
ACCAAGAGAA AACACGATAA TGAAGGTTCT GGAAGCAAAA GGCCCAAGGT GGAGTATTCA 
GAAGAGGAGC TGAAGACCCA CATCAGCAAG GGTACGCTGG GCAAGTTCAC TGTGCCCATG 
CTGAAAGAGG CCTGCCGGGC TTACGGGCTG AAGAGTGGGC TGAAGAAGCA GGAGCTGCTG 
GAAGCCCTCA CCAAGCACTT CCAGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275905.1
CDS	132..1961
Translation	MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD

Target ORF information:

RefSeq Version	NM_001288976.2
Organism	Homo sapiens(human)
Definition	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288976.2

ORF Insert Sequence:

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGTGTAT CCAAAGTGTG TACATCAGTA AGATCATAAG CAGTGATCGA 
GATCTCTTGG CTGTGGTGTT CTATGGTACC GAGAAAGACA AAAATTCAGT GAATTTTAAA 
AATATTTACG TCTTACAGGA GCTGGATAAT CCAGGTGCAA AACGAATTCT AGAGCTTGAC 
CAGTTTAAGG GGCAGCAGGG ACAAAAACGT TTCCAAGACA TGATGGGCCA CGGATCTGAC 
TACTCACTCA GTGAAGTGCT GTGGGTCTGT GCCAACCTCT TTAGTGATGT CCAATTCAAG 
ATGAGTCATA AGAGGATCAT GCTGTTCACC AATGAAGACA ACCCCCATGG CAATGACAGT 
GCCAAAGCCA GCCGGGCCAG GACCAAAGCC GGTGATCTCC GAGATACAGG CATCTTCCTT 
GACTTGATGC ACCTGAAGAA ACCTGGGGGC TTTGACATAT CCTTGTTCTA CAGAGATATC 
ATCAGCATAG CAGAGGATGA GGACCTCAGG GTTCACTTTG AGGAATCCAG CAAGCTAGAA 
GACCTGTTGC GGAAGGTTCG CGCCAAGGAG ACCAGGAAGC GAGCACTCAG CAGGTTAAAG 
CTGAAGCTCA ACAAAGATAT AGTGATCTCT GTGGGCATTT ATAATCTGGT CCAGAAGGCT 
CTCAAGCCTC CTCCAATAAA GCTCTATCGG GAAACAAATG AACCAGTGAA AACCAAGACC 
CGGACCTTTA ATACAAGTAC AGGCGGTTTG CTTCTGCCTA GCGATACCAA GAGGTCTCAG 
ATCTATGGGA GTCGTCAGAT TATACTGGAG AAAGAGGAAA CAGAAGAGCT AAAACGGTTT 
GATGATCCAG GTTTGATGCT CATGGGTTTC AAGCCGTTGG TACTGCTGAA GAAACACCAT 
TACCTGAGGC CCTCCCTGTT CGTGTACCCA GAGGAGTCGC TGGTGATTGG GAGCTCAACC 
CTGTTCAGTG CTCTGCTCAT CAAGTGTCTG GAGAAGGAGG TTGCAGCATT GTGCAGATAC 
ACACCCCGCA GGAACATCCC TCCTTATTTT GTGGCTTTGG TGCCACAGGA AGAAGAGTTG 
GATGACCAGA AAATTCAGGT GACTCCTCCA GGCTTCCAGC TGGTCTTTTT ACCCTTTGCT 
GATGATAAAA GGAAGATGCC CTTTACTGAA AAAATCATGG CAACTCCAGA GCAGGTGGGC 
AAGATGAAGG CTATCGTTGA GAAGCTTCGC TTCACATACA GAAGTGACAG CTTTGAGAAC 
CCCGTGCTGC AGCAGCACTT CAGGAACCTG GAGGCCTTGG CCTTGGATTT GATGGAGCCG 
GAACAAGCAG TGGACCTGAC ATTGCCCAAG GTTGAAGCAA TGAATAAAAG ACTGGGCTCC 
TTGGTGGATG AGTTTAAGGA GCTTGTTTAC CCACCAGATT ACAATCCTGA AGGGAAAGTT 
ACCAAGAGAA AACACGATAA TGAAGGTTCT GGAAGCAAAA GGCCCAAGGT GGAGTATTCA 
GAAGAGGAGC TGAAGACCCA CATCAGCAAG GGTACGCTGG GCAAGTTCAC TGTGCCCATG 
CTGAAAGAGG CCTGCCGGGC TTACGGGCTG AAGAGTGGGC TGAAGAAGCA GGAGCTGCTG 
GAAGCCCTCA CCAAGCACTT CCAGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRCC6 ( NM_001469.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001460.1 Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 1, mRNA.

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CloneID	OHu27504
Clone ID Related Accession (Same CDS sequence)	NM_001288976.1 , NM_001469.5 , NM_001288976.2 , NM_001469.4
Accession Version	NM_001469.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1830bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550851200000
Organism	Homo sapiens(human)
Product	X-ray repair cross-complementing protein 6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB057280.1, DC386009.1, CD683757.1, AK055786.1, BC018259.2 and BC012154.2. On Jan 10, 2014 this sequence version replaced NM_001469.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.37159.1, SRR1803614.193859.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGTGTAT CCAAAGTGTG TACATCAGTA AGATCATAAG CAGTGATCGA 
GATCTCTTGG CTGTGGTGTT CTATGGTACC GAGAAAGACA AAAATTCAGT GAATTTTAAA 
AATATTTACG TCTTACAGGA GCTGGATAAT CCAGGTGCAA AACGAATTCT AGAGCTTGAC 
CAGTTTAAGG GGCAGCAGGG ACAAAAACGT TTCCAAGACA TGATGGGCCA CGGATCTGAC 
TACTCACTCA GTGAAGTGCT GTGGGTCTGT GCCAACCTCT TTAGTGATGT CCAATTCAAG 
ATGAGTCATA AGAGGATCAT GCTGTTCACC AATGAAGACA ACCCCCATGG CAATGACAGT 
GCCAAAGCCA GCCGGGCCAG GACCAAAGCC GGTGATCTCC GAGATACAGG CATCTTCCTT 
GACTTGATGC ACCTGAAGAA ACCTGGGGGC TTTGACATAT CCTTGTTCTA CAGAGATATC 
ATCAGCATAG CAGAGGATGA GGACCTCAGG GTTCACTTTG AGGAATCCAG CAAGCTAGAA 
GACCTGTTGC GGAAGGTTCG CGCCAAGGAG ACCAGGAAGC GAGCACTCAG CAGGTTAAAG 
CTGAAGCTCA ACAAAGATAT AGTGATCTCT GTGGGCATTT ATAATCTGGT CCAGAAGGCT 
CTCAAGCCTC CTCCAATAAA GCTCTATCGG GAAACAAATG AACCAGTGAA AACCAAGACC 
CGGACCTTTA ATACAAGTAC AGGCGGTTTG CTTCTGCCTA GCGATACCAA GAGGTCTCAG 
ATCTATGGGA GTCGTCAGAT TATACTGGAG AAAGAGGAAA CAGAAGAGCT AAAACGGTTT 
GATGATCCAG GTTTGATGCT CATGGGTTTC AAGCCGTTGG TACTGCTGAA GAAACACCAT 
TACCTGAGGC CCTCCCTGTT CGTGTACCCA GAGGAGTCGC TGGTGATTGG GAGCTCAACC 
CTGTTCAGTG CTCTGCTCAT CAAGTGTCTG GAGAAGGAGG TTGCAGCATT GTGCAGATAC 
ACACCCCGCA GGAACATCCC TCCTTATTTT GTGGCTTTGG TGCCACAGGA AGAAGAGTTG 
GATGACCAGA AAATTCAGGT GACTCCTCCA GGCTTCCAGC TGGTCTTTTT ACCCTTTGCT 
GATGATAAAA GGAAGATGCC CTTTACTGAA AAAATCATGG CAACTCCAGA GCAGGTGGGC 
AAGATGAAGG CTATCGTTGA GAAGCTTCGC TTCACATACA GAAGTGACAG CTTTGAGAAC 
CCCGTGCTGC AGCAGCACTT CAGGAACCTG GAGGCCTTGG CCTTGGATTT GATGGAGCCG 
GAACAAGCAG TGGACCTGAC ATTGCCCAAG GTTGAAGCAA TGAATAAAAG ACTGGGCTCC 
TTGGTGGATG AGTTTAAGGA GCTTGTTTAC CCACCAGATT ACAATCCTGA AGGGAAAGTT 
ACCAAGAGAA AACACGATAA TGAAGGTTCT GGAAGCAAAA GGCCCAAGGT GGAGTATTCA 
GAAGAGGAGC TGAAGACCCA CATCAGCAAG GGTACGCTGG GCAAGTTCAC TGTGCCCATG 
CTGAAAGAGG CCTGCCGGGC TTACGGGCTG AAGAGTGGGC TGAAGAAGCA GGAGCTGCTG 
GAAGCCCTCA CCAAGCACTT CCAGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001460.1
CDS	199..2028
Translation	MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD

Target ORF information:

RefSeq Version	NM_001469.4
Organism	Homo sapiens(human)
Definition	Homo sapiens X-ray repair cross complementing 6 (XRCC6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001469.4

ORF Insert Sequence:

ATGTCAGGGT GGGAGTCATA TTACAAAACC GAGGGCGATG AAGAAGCAGA GGAAGAACAA 
GAAGAGAACC TTGAAGCAAG TGGAGACTAT AAATATTCAG GAAGAGATAG TTTGATTTTT 
TTGGTTGATG CCTCCAAGGC TATGTTTGAA TCTCAGAGTG AAGATGAGTT GACACCTTTT 
GACATGAGCA TCCAGTGTAT CCAAAGTGTG TACATCAGTA AGATCATAAG CAGTGATCGA 
GATCTCTTGG CTGTGGTGTT CTATGGTACC GAGAAAGACA AAAATTCAGT GAATTTTAAA 
AATATTTACG TCTTACAGGA GCTGGATAAT CCAGGTGCAA AACGAATTCT AGAGCTTGAC 
CAGTTTAAGG GGCAGCAGGG ACAAAAACGT TTCCAAGACA TGATGGGCCA CGGATCTGAC 
TACTCACTCA GTGAAGTGCT GTGGGTCTGT GCCAACCTCT TTAGTGATGT CCAATTCAAG 
ATGAGTCATA AGAGGATCAT GCTGTTCACC AATGAAGACA ACCCCCATGG CAATGACAGT 
GCCAAAGCCA GCCGGGCCAG GACCAAAGCC GGTGATCTCC GAGATACAGG CATCTTCCTT 
GACTTGATGC ACCTGAAGAA ACCTGGGGGC TTTGACATAT CCTTGTTCTA CAGAGATATC 
ATCAGCATAG CAGAGGATGA GGACCTCAGG GTTCACTTTG AGGAATCCAG CAAGCTAGAA 
GACCTGTTGC GGAAGGTTCG CGCCAAGGAG ACCAGGAAGC GAGCACTCAG CAGGTTAAAG 
CTGAAGCTCA ACAAAGATAT AGTGATCTCT GTGGGCATTT ATAATCTGGT CCAGAAGGCT 
CTCAAGCCTC CTCCAATAAA GCTCTATCGG GAAACAAATG AACCAGTGAA AACCAAGACC 
CGGACCTTTA ATACAAGTAC AGGCGGTTTG CTTCTGCCTA GCGATACCAA GAGGTCTCAG 
ATCTATGGGA GTCGTCAGAT TATACTGGAG AAAGAGGAAA CAGAAGAGCT AAAACGGTTT 
GATGATCCAG GTTTGATGCT CATGGGTTTC AAGCCGTTGG TACTGCTGAA GAAACACCAT 
TACCTGAGGC CCTCCCTGTT CGTGTACCCA GAGGAGTCGC TGGTGATTGG GAGCTCAACC 
CTGTTCAGTG CTCTGCTCAT CAAGTGTCTG GAGAAGGAGG TTGCAGCATT GTGCAGATAC 
ACACCCCGCA GGAACATCCC TCCTTATTTT GTGGCTTTGG TGCCACAGGA AGAAGAGTTG 
GATGACCAGA AAATTCAGGT GACTCCTCCA GGCTTCCAGC TGGTCTTTTT ACCCTTTGCT 
GATGATAAAA GGAAGATGCC CTTTACTGAA AAAATCATGG CAACTCCAGA GCAGGTGGGC 
AAGATGAAGG CTATCGTTGA GAAGCTTCGC TTCACATACA GAAGTGACAG CTTTGAGAAC 
CCCGTGCTGC AGCAGCACTT CAGGAACCTG GAGGCCTTGG CCTTGGATTT GATGGAGCCG 
GAACAAGCAG TGGACCTGAC ATTGCCCAAG GTTGAAGCAA TGAATAAAAG ACTGGGCTCC 
TTGGTGGATG AGTTTAAGGA GCTTGTTTAC CCACCAGATT ACAATCCTGA AGGGAAAGTT 
ACCAAGAGAA AACACGATAA TGAAGGTTCT GGAAGCAAAA GGCCCAAGGT GGAGTATTCA 
GAAGAGGAGC TGAAGACCCA CATCAGCAAG GGTACGCTGG GCAAGTTCAC TGTGCCCATG 
CTGAAAGAGG CCTGCCGGGC TTACGGGCTG AAGAGTGGGC TGAAGAAGCA GGAGCTGCTG 
GAAGCCCTCA CCAAGCACTT CCAGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.
Nature immunology20(4)493-502(2019 04)
Hubel P,Urban C,Bergant V,Schneider WM,Knauer B,Stukalov A,Scaturro P,Mann A,Brunotte L,Hoffmann HH,Schoggins JW,Schwemmle M,Mann M,Rice CM,Pichlmair A

The deoxyribose phosphate lyase of DNA polymerase β suppresses a processive DNA synthesis to prevent trinucleotide repeat instability.
Nucleic acids research46(17)8940-8952(2018 09)
Lai Y,Weizmann Y,Liu Y

Ku70 N-terminal lysines acetylation/deacetylation is required for radiation-induced DNA-double strand breaks repair.
Neoplasma65(5)708-719(2018 Sep)
Al Emam A,Arbon D,Jeeves M,Kysela B

Protective effects of SIRT6 against lipopolysaccharide (LPS) are mediated by deacetylation of Ku70.
Molecular immunology101312-318(2018 09)
Zhang L,Bai L,Ren Q,Sun G,Si Y

KU70 Inhibition Impairs Both Non-Homologous End Joining and Homologous Recombination DNA Damage Repair Through SHP-1 Induced Dephosphorylation of SIRT1 in T-Cell Acute Lymphoblastic Leukemia (T-ALL) [corrected].
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology49(6)2111-2123(2018)
Yu W,Li L,Wang G,Zhang W,Xu J,Liang A

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XRCC6 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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