ETFB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ETFB
Entrez Gene ID	2109
Full Name	electron transfer flavoprotein beta subunit
Synonyms	FP585,MADD
General protein information	Preferred Names electron transfer flavoprotein beta subunit Names electron transfer flavoprotein subunit beta beta-ETF electron transfer flavoprotein, beta polypeptide electron-transferring-flavoprotein, beta polypeptide
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.41
Summary	This gene encodes electron-transfer-flavoprotein, beta polypeptide, which shuttles electrons between primary flavoprotein dehydrogenases involved in mitochondrial fatty acid and amino acid catabolism and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. The gene deficiencies have been implicated in type II glutaricaciduria. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	130410
Disorder Html:	Glutaric acidemia IIB, 231680 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001985.3	NP_001976.1	electron transfer flavoprotein subunit beta isoform 1
NM_001985.2	NP_001976.1	electron transfer flavoprotein subunit beta isoform 1
XM_024451418.1	XP_024307186.1	electron transfer flavoprotein subunit beta isoform X1
NM_001014763.1	NP_001014763.1	electron transfer flavoprotein subunit beta isoform 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ETFB	XP_533603.2
Bos taurus (cattle)	ETFB	NP_001033671.1
Mus musculus (house mouse)	Etfb	NP_080971.2
Xenopus tropicalis (tropical clawed frog)	etfb	NP_989154.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004653	XP_316741.3
Neurospora crassa	NCU07733	XP_961983.1
Homo sapiens (human)	ETFB	NP_001976.1
Macaca mulatta (Rhesus monkey)	ETFB	XP_001116320.1
Drosophila melanogaster (fruit fly)	CG7834	NP_651727.1
Caenorhabditis elegans (roundworm)	CELE_F23C8.5	NP_490973.2
Magnaporthe oryzae (rice blast fungus)	MGG_01744	XP_003714741.1
Danio rerio (zebrafish)	etfb	NP_998163.1
Rattus norvegicus (Norway rat)	Etfb	NP_001004220.1
Schizosaccharomyces pombe (fission yeast)	SPAC1805.02c	NP_593913.1
Kluyveromyces lactis	KLLA0E16391g	XP_454688.1
Saccharomyces cerevisiae (baker's yeast)	CIR1	NP_011723.1
Arabidopsis thaliana (thale cress)	ETFBETA	NP_199156.1
Oryza sativa (rice)	Os04g0182800	NP_001052183.1

Gene Ontology
Bibliography

Related articles in PubMed

Oxidation of the FAD cofactor to the 8-formyl-derivative in human electron-transferring flavoprotein.
Augustin P, Toplak M, Fuchs K, Gerstmann EC, Prassl R, Winkler A, Macheroux P
The Journal of biological chemistry293(8)2829-2840(2018 02)

Exome array analysis identifies ETFB as a novel susceptibility gene for anthracycline-induced cardiotoxicity in cancer patients.
Ruiz-Pinto S, Pita G, Martín M, Alonso-Gordoa T, Barnes DR, Alonso MR, Herraez B, García-Miguel P, Alonso J, Pérez-Martínez A, Cartón AJ, Gutiérrez-Larraya F, García-Sáenz JA, Benítez J, Easton DF, Patiño-García A, González-Neira A
Breast cancer research and treatment167(1)249-256(2018 01)

ATP5B and ETFB metabolic markers in children with congenital hydronephrosis.
Zhao Q, Yang Y, Wang C, Hou Y, Chen H
Molecular medicine reports14(6)5111-5115(2016 Dec)

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function.
Floyd BJ, Wilkerson EM, Veling MT, Minogue CE, Xia C, Beebe ET, Wrobel RL, Cho H, Kremer LS, Alston CL, Gromek KA, Dolan BK, Ulbrich A, Stefely JA, Bohl SL, Werner KM, Jochem A, Westphall MS, Rensvold JW, Taylor RW, Prokisch H, Kim JP, Coon JJ, Pagliarini DJ
Molecular cell63(4)621-632(2016 08)

The decreased expression of electron transfer flavoprotein β is associated with tubular cell apoptosis in diabetic nephropathy.
Wang H, Zhang H, Chen X, Zhao T, Kong Q, Yan M, Zhang B, Sun S, Lan HY, Li N, Li P
International journal of molecular medicine37(5)1290-8(2016 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ETFB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ETFB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04154	NM_001014763.1 Latest version!	Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu104642	XM_024451418.1 Latest version!	Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu18624	NM_001985.3 Latest version!	Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu18624	NM_001985.2	Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ETFB ( NM_001014763.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001014763.1 Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04154
Clone ID Related Accession (Same CDS sequence)	NM_001014763.1
Accession Version	NM_001014763.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1562169600000
Organism	Homo sapiens(human)
Product	electron transfer flavoprotein subunit beta isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK055285.1, AF370381.1 and BG281641.1. Transcript Variant: This variant (2) lacks the 5' exon but has an alternate 5' segment, as compared to variant 1. The encoded isoform (2) has a longer and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.571283.1, AK055285.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTACCTCT CACTGTGGGT TACCATAAAT ACTGTAAATT TGAGAAACAC TCTTTCAGGC 
CTGAGAGGAG CAGTGACAAC AGTAGGGATG ATCAAGTCAG ATGTCCCTGG TACCCAGGAA 
TGGCTGGATG AGAGAAGGAG ACAGGGTGAC CTGCCCCTGC CTACAAACTC TAACCCAGTT 
CTGTCCCTGG AGCTGTGTGA CCCCGGACAA GGCCCTGCCC CTTTCCAGGC TGTCGTTGTC 
CTCATCCAGC CTGGGAGAGG GTTGGCGCTG AGGCCCCCAC CTTCTTGCCT GTTTCCTCCT 
GACCCCACCC CTTCCCCTCC TGCTGGGCAG ATCCGAGTGA AGCCTGACAG GACCGGTGTG 
GTCACGGATG GTGTGAAGCA CTCCATGAAC CCCTTCTGTG AGATCGCGGT GGAGGAGGCT 
GTGCGGCTCA AGGAGAAGAA GCTGGTGAAG GAGGTCATCG CCGTCAGCTG TGGGCCTGCA 
CAGTGCCAGG AGACGATTCG TACCGCCCTG GCCATGGGTG CAGACCGAGG TATCCACGTG 
GAGGTGCCCC CAGCAGAAGC AGAACGCTTG GGTCCCCTGC AGGTGGCTCG GGTCCTGGCC 
AAGCTGGCAG AGAAGGAGAA GGTGGACCTG GTGCTGCTGG GCAAACAGGC CATCGATGAT 
GACTGTAACC AGACAGGGCA GATGACAGCT GGATTTCTTG ACTGGCCACA GGGCACATTC 
GCCTCCCAGG TGACGCTGGA GGGGGACAAG TTGAAAGTGG AGCGGGAGAT CGATGGGGGC 
CTGGAGACCC TGCGCCTGAA GCTGCCAGCT GTGGTGACAG CTGACCTGAG GCTCAACGAG 
CCCCGCTACG CCACGCTGCC CAACATCATG AAAGCCAAGA AGAAGAAGAT CGAGGTGATC 
AAGCCTGGGG ACCTGGGTGT GGACCTGACC TCCAAGCTCT CTGTGATCAG TGTGGAGGAC 
CCGCCCCAGC GCACGGCCGG CGTCAAGGTG GAGACCACTG AGGACCTGGT GGCCAAGCTG 
AAGGAGATTG GGCGGATTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014763.1
CDS	205..1245
Translation	MYLSLWVTINTVNLRNTLSGLRGAVTTVGMIKSDVPGTQEWLDERRRQGDLPLPTNSNPVLSLELCDPGQGPAPFQAVVVLIQPGRGLALRPPPSCLFPPDPTPSPPAGQIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKLKEIGRI

Target ORF information:

RefSeq Version	NM_001014763.1
Organism	Homo sapiens(human)
Definition	Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014763.1

ORF Insert Sequence:

ATGTACCTCT CACTGTGGGT TACCATAAAT ACTGTAAATT TGAGAAACAC TCTTTCAGGC 
CTGAGAGGAG CAGTGACAAC AGTAGGGATG ATCAAGTCAG ATGTCCCTGG TACCCAGGAA 
TGGCTGGATG AGAGAAGGAG ACAGGGTGAC CTGCCCCTGC CTACAAACTC TAACCCAGTT 
CTGTCCCTGG AGCTGTGTGA CCCCGGACAA GGCCCTGCCC CTTTCCAGGC TGTCGTTGTC 
CTCATCCAGC CTGGGAGAGG GTTGGCGCTG AGGCCCCCAC CTTCTTGCCT GTTTCCTCCT 
GACCCCACCC CTTCCCCTCC TGCTGGGCAG ATCCGAGTGA AGCCTGACAG GACCGGTGTG 
GTCACGGATG GTGTGAAGCA CTCCATGAAC CCCTTCTGTG AGATCGCGGT GGAGGAGGCT 
GTGCGGCTCA AGGAGAAGAA GCTGGTGAAG GAGGTCATCG CCGTCAGCTG TGGGCCTGCA 
CAGTGCCAGG AGACGATTCG TACCGCCCTG GCCATGGGTG CAGACCGAGG TATCCACGTG 
GAGGTGCCCC CAGCAGAAGC AGAACGCTTG GGTCCCCTGC AGGTGGCTCG GGTCCTGGCC 
AAGCTGGCAG AGAAGGAGAA GGTGGACCTG GTGCTGCTGG GCAAACAGGC CATCGATGAT 
GACTGTAACC AGACAGGGCA GATGACAGCT GGATTTCTTG ACTGGCCACA GGGCACATTC 
GCCTCCCAGG TGACGCTGGA GGGGGACAAG TTGAAAGTGG AGCGGGAGAT CGATGGGGGC 
CTGGAGACCC TGCGCCTGAA GCTGCCAGCT GTGGTGACAG CTGACCTGAG GCTCAACGAG 
CCCCGCTACG CCACGCTGCC CAACATCATG AAAGCCAAGA AGAAGAAGAT CGAGGTGATC 
AAGCCTGGGG ACCTGGGTGT GGACCTGACC TCCAAGCTCT CTGTGATCAG TGTGGAGGAC 
CCGCCCCAGC GCACGGCCGG CGTCAAGGTG GAGACCACTG AGGACCTGGT GGCCAAGCTG 
AAGGAGATTG GGCGGATTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ETFB ( XM_024451418.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307186.1 Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu104642
Clone ID Related Accession (Same CDS sequence)	XM_024451418.1
Accession Version	XM_024451418.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	electron transfer flavoprotein subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCCCT TCTGTGAGAT CGCGGTGGAG GAGGCTGTGC GGCTCAAGGA GAAGAAGCTG 
GTGAAGGAGG TCATCGCCGT CAGCTGTGGG CCTGCACAGT GCCAGGAGAC GATTCGTACC 
GCCCTGGCCA TGGGTGCAGA CCGAGGTATC CACGTGGAGG TGCCCCCAGC AGAAGCAGAA 
CGCTTGGGTC CCCTGCAGGT GGCTCGGGTC CTGGCCAAGC TGGCAGAGAA GGAGAAGGTG 
GACCTGGTGC TGCTGGGCAA ACAGGCCATC GATGATGACT GTAACCAGAC AGGGCAGATG 
ACAGCTGGAT TTCTTGACTG GCCACAGGGC ACATTCGCCT CCCAGGTGAC GCTGGAGGGG 
GACAAGTTGA AAGTGGAGCG GGAGATCGAT GGGGGCCTGG AGACCCTGCG CCTGAAGCTG 
CCAGCTGTGG TGACAGCTGA CCTGAGGCTC AACGAGCCCC GCTACGCCAC GCTGCCCAAC 
ATCATGAAAG CCAAGAAGAA GAAGATCGAG GTGATCAAGC CTGGGGACCT GGGTGTGGAC 
CTGACCTCCA AGCTCTCTGT GATCAGTGTG GAGGACCCGC CCCAGCGCAC GGCCGGCGTC 
AAGGTGGAGA CCACTGAGGA CCTGGTGGCC AAGCTGAAGG AGATTGGGCG GATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307186.1
CDS	184..840
Translation	MNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKLKEIGRI

Target ORF information:

RefSeq Version	XM_024451418.1
Organism	Homo sapiens(human)
Definition	Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451418.1

ORF Insert Sequence:

ATGAACCCCT TCTGTGAGAT CGCGGTGGAG GAGGCTGTGC GGCTCAAGGA GAAGAAGCTG 
GTGAAGGAGG TCATCGCCGT CAGCTGTGGG CCTGCACAGT GCCAGGAGAC GATTCGTACC 
GCCCTGGCCA TGGGTGCAGA CCGAGGTATC CACGTGGAGG TGCCCCCAGC AGAAGCAGAA 
CGCTTGGGTC CCCTGCAGGT GGCTCGGGTC CTGGCCAAGC TGGCAGAGAA GGAGAAGGTG 
GACCTGGTGC TGCTGGGCAA ACAGGCCATC GATGATGACT GTAACCAGAC AGGGCAGATG 
ACAGCTGGAT TTCTTGACTG GCCACAGGGC ACATTCGCCT CCCAGGTGAC GCTGGAGGGG 
GACAAGTTGA AAGTGGAGCG GGAGATCGAT GGGGGCCTGG AGACCCTGCG CCTGAAGCTG 
CCAGCTGTGG TGACAGCTGA CCTGAGGCTC AACGAGCCCC GCTACGCCAC GCTGCCCAAC 
ATCATGAAAG CCAAGAAGAA GAAGATCGAG GTGATCAAGC CTGGGGACCT GGGTGTGGAC 
CTGACCTCCA AGCTCTCTGT GATCAGTGTG GAGGACCCGC CCCAGCGCAC GGCCGGCGTC 
AAGGTGGAGA CCACTGAGGA CCTGGTGGCC AAGCTGAAGG AGATTGGGCG GATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ETFB ( NM_001985.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001976.1 Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18624
Clone ID Related Accession (Same CDS sequence)	NM_001985.3 , NM_001985.2
Accession Version	NM_001985.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569772800000
Organism	Homo sapiens(human)
Product	electron transfer flavoprotein subunit beta isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG399783.1, X71129.1 and BG281641.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_001985.2. Transcript Variant: This variant (1) encodes the shorter isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.299848.1, SRR5189661.44691.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGC TGCGCGTGCT CGTAGCTGTC AAGAGGGTCA TCGACTACGC CGTGAAGATC 
CGAGTGAAGC CTGACAGGAC CGGTGTGGTC ACGGATGGTG TGAAGCACTC CATGAACCCC 
TTCTGTGAGA TCGCGGTGGA GGAGGCTGTG CGGCTCAAGG AGAAGAAGCT GGTGAAGGAG 
GTCATCGCCG TCAGCTGTGG GCCTGCACAG TGCCAGGAGA CGATTCGTAC CGCCCTGGCC 
ATGGGTGCAG ACCGAGGTAT CCACGTGGAG GTGCCCCCAG CAGAAGCAGA ACGCTTGGGT 
CCCCTGCAGG TGGCTCGGGT CCTGGCCAAG CTGGCAGAGA AGGAGAAGGT GGACCTGGTG 
CTGCTGGGCA AACAGGCCAT CGATGATGAC TGTAACCAGA CAGGGCAGAT GACAGCTGGA 
TTTCTTGACT GGCCACAGGG CACATTCGCC TCCCAGGTGA CGCTGGAGGG GGACAAGTTG 
AAAGTGGAGC GGGAGATCGA TGGGGGCCTG GAGACCCTGC GCCTGAAGCT GCCAGCTGTG 
GTGACAGCTG ACCTGAGGCT CAACGAGCCC CGCTACGCCA CGCTGCCCAA CATCATGAAA 
GCCAAGAAGA AGAAGATCGA GGTGATCAAG CCTGGGGACC TGGGTGTGGA CCTGACCTCC 
AAGCTCTCTG TGATCAGTGT GGAGGACCCG CCCCAGCGCA CGGCCGGCGT CAAGGTGGAG 
ACCACTGAGG ACCTGGTGGC CAAGCTGAAG GAGATTGGGC GGATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001976.1
CDS	63..830
Translation	MAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKLKEIGRI

Target ORF information:

RefSeq Version	NM_001985.3
Organism	Homo sapiens(human)
Definition	Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001985.3

ORF Insert Sequence:

ATGGCGGAGC TGCGCGTGCT CGTAGCTGTC AAGAGGGTCA TCGACTACGC CGTGAAGATC 
CGAGTGAAGC CTGACAGGAC CGGTGTGGTC ACGGATGGTG TGAAGCACTC CATGAACCCC 
TTCTGTGAGA TCGCGGTGGA GGAGGCTGTG CGGCTCAAGG AGAAGAAGCT GGTGAAGGAG 
GTCATCGCCG TCAGCTGTGG GCCTGCACAG TGCCAGGAGA CGATTCGTAC CGCCCTGGCC 
ATGGGTGCAG ACCGAGGTAT CCACGTGGAG GTGCCCCCAG CAGAAGCAGA ACGCTTGGGT 
CCCCTGCAGG TGGCTCGGGT CCTGGCCAAG CTGGCAGAGA AGGAGAAGGT GGACCTGGTG 
CTGCTGGGCA AACAGGCCAT CGATGATGAC TGTAACCAGA CAGGGCAGAT GACAGCTGGA 
TTTCTTGACT GGCCACAGGG CACATTCGCC TCCCAGGTGA CGCTGGAGGG GGACAAGTTG 
AAAGTGGAGC GGGAGATCGA TGGGGGCCTG GAGACCCTGC GCCTGAAGCT GCCAGCTGTG 
GTGACAGCTG ACCTGAGGCT CAACGAGCCC CGCTACGCCA CGCTGCCCAA CATCATGAAA 
GCCAAGAAGA AGAAGATCGA GGTGATCAAG CCTGGGGACC TGGGTGTGGA CCTGACCTCC 
AAGCTCTCTG TGATCAGTGT GGAGGACCCG CCCCAGCGCA CGGCCGGCGT CAAGGTGGAG 
ACCACTGAGG ACCTGGTGGC CAAGCTGAAG GAGATTGGGC GGATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ETFB ( NM_001985.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001976.1 Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18624
Clone ID Related Accession (Same CDS sequence)	NM_001985.3 , NM_001985.2
Accession Version	NM_001985.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550246400000
Organism	Homo sapiens(human)
Product	electron transfer flavoprotein subunit beta isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG399783.1, X71129.1 and BG281641.1. This sequence is a reference standard in the RefSeqGene project. On Apr 8, 2005 this sequence version replaced NM_001985.1. Transcript Variant: This variant (1) encodes the shorter isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.560214.1, BI757760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGC TGCGCGTGCT CGTAGCTGTC AAGAGGGTCA TCGACTACGC CGTGAAGATC 
CGAGTGAAGC CTGACAGGAC CGGTGTGGTC ACGGATGGTG TGAAGCACTC CATGAACCCC 
TTCTGTGAGA TCGCGGTGGA GGAGGCTGTG CGGCTCAAGG AGAAGAAGCT GGTGAAGGAG 
GTCATCGCCG TCAGCTGTGG GCCTGCACAG TGCCAGGAGA CGATTCGTAC CGCCCTGGCC 
ATGGGTGCAG ACCGAGGTAT CCACGTGGAG GTGCCCCCAG CAGAAGCAGA ACGCTTGGGT 
CCCCTGCAGG TGGCTCGGGT CCTGGCCAAG CTGGCAGAGA AGGAGAAGGT GGACCTGGTG 
CTGCTGGGCA AACAGGCCAT CGATGATGAC TGTAACCAGA CAGGGCAGAT GACAGCTGGA 
TTTCTTGACT GGCCACAGGG CACATTCGCC TCCCAGGTGA CGCTGGAGGG GGACAAGTTG 
AAAGTGGAGC GGGAGATCGA TGGGGGCCTG GAGACCCTGC GCCTGAAGCT GCCAGCTGTG 
GTGACAGCTG ACCTGAGGCT CAACGAGCCC CGCTACGCCA CGCTGCCCAA CATCATGAAA 
GCCAAGAAGA AGAAGATCGA GGTGATCAAG CCTGGGGACC TGGGTGTGGA CCTGACCTCC 
AAGCTCTCTG TGATCAGTGT GGAGGACCCG CCCCAGCGCA CGGCCGGCGT CAAGGTGGAG 
ACCACTGAGG ACCTGGTGGC CAAGCTGAAG GAGATTGGGC GGATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001976.1
CDS	93..860
Translation	MAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKLKEIGRI

Target ORF information:

RefSeq Version	NM_001985.2
Organism	Homo sapiens(human)
Definition	Homo sapiens electron transfer flavoprotein subunit beta (ETFB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001985.2

ORF Insert Sequence:

ATGGCGGAGC TGCGCGTGCT CGTAGCTGTC AAGAGGGTCA TCGACTACGC CGTGAAGATC 
CGAGTGAAGC CTGACAGGAC CGGTGTGGTC ACGGATGGTG TGAAGCACTC CATGAACCCC 
TTCTGTGAGA TCGCGGTGGA GGAGGCTGTG CGGCTCAAGG AGAAGAAGCT GGTGAAGGAG 
GTCATCGCCG TCAGCTGTGG GCCTGCACAG TGCCAGGAGA CGATTCGTAC CGCCCTGGCC 
ATGGGTGCAG ACCGAGGTAT CCACGTGGAG GTGCCCCCAG CAGAAGCAGA ACGCTTGGGT 
CCCCTGCAGG TGGCTCGGGT CCTGGCCAAG CTGGCAGAGA AGGAGAAGGT GGACCTGGTG 
CTGCTGGGCA AACAGGCCAT CGATGATGAC TGTAACCAGA CAGGGCAGAT GACAGCTGGA 
TTTCTTGACT GGCCACAGGG CACATTCGCC TCCCAGGTGA CGCTGGAGGG GGACAAGTTG 
AAAGTGGAGC GGGAGATCGA TGGGGGCCTG GAGACCCTGC GCCTGAAGCT GCCAGCTGTG 
GTGACAGCTG ACCTGAGGCT CAACGAGCCC CGCTACGCCA CGCTGCCCAA CATCATGAAA 
GCCAAGAAGA AGAAGATCGA GGTGATCAAG CCTGGGGACC TGGGTGTGGA CCTGACCTCC 
AAGCTCTCTG TGATCAGTGT GGAGGACCCG CCCCAGCGCA CGGCCGGCGT CAAGGTGGAG 
ACCACTGAGG ACCTGGTGGC CAAGCTGAAG GAGATTGGGC GGATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Oxidation of the FAD cofactor to the 8-formyl-derivative in human electron-transferring flavoprotein.
The Journal of biological chemistry293(8)2829-2840(2018 02)
Augustin P,Toplak M,Fuchs K,Gerstmann EC,Prassl R,Winkler A,Macheroux P

Exome array analysis identifies ETFB as a novel susceptibility gene for anthracycline-induced cardiotoxicity in cancer patients.
Breast cancer research and treatment167(1)249-256(2018 01)
Ruiz-Pinto S,Pita G,Martín M,Alonso-Gordoa T,Barnes DR,Alonso MR,Herraez B,García-Miguel P,Alonso J,Pérez-Martínez A,Cartón AJ,Gutiérrez-Larraya F,García-Sáenz JA,Benítez J,Easton DF,Patiño-García A,González-Neira A

ATP5B and ETFB metabolic markers in children with congenital hydronephrosis.
Molecular medicine reports14(6)5111-5115(2016 Dec)
Zhao Q,Yang Y,Wang C,Hou Y,Chen H

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function.
Molecular cell63(4)621-632(2016 08)
Floyd BJ,Wilkerson EM,Veling MT,Minogue CE,Xia C,Beebe ET,Wrobel RL,Cho H,Kremer LS,Alston CL,Gromek KA,Dolan BK,Ulbrich A,Stefely JA,Bohl SL,Werner KM,Jochem A,Westphall MS,Rensvold JW,Taylor RW,Prokisch H,Kim JP,Coon JJ,Pagliarini DJ

The decreased expression of electron transfer flavoprotein β is associated with tubular cell apoptosis in diabetic nephropathy.
International journal of molecular medicine37(5)1290-8(2016 May)
Wang H,Zhang H,Chen X,Zhao T,Kong Q,Yan M,Zhang B,Sun S,Lan HY,Li N,Li P

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ETFB cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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