CSRP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CSRP2
Entrez Gene ID	1466
Full Name	cysteine and glycine rich protein 2
Synonyms	CRP2,LMO5,SmLIM
General protein information	Preferred Names cysteine and glycine rich protein 2 Names cysteine and glycine-rich protein 2 LIM domain only 5, smooth muscle LIM domain only protein 5 LMO-5 cysteine-rich protein 2 smooth muscle cell LIM protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q21.2
Summary	CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
Disorder MIM:	601871

mRNA and Protein(s)

mRNA	Protein	Name
NM_001300965.1	NP_001287894.1	cysteine and glycine-rich protein 2
NM_001321.3	NP_001312.1	cysteine and glycine-rich protein 2
NM_001321.2	NP_001312.1	cysteine and glycine-rich protein 2
NM_001300965.2	NP_001287894.1	cysteine and glycine-rich protein 2

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	csrp2	NP_957191.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012305	XP_551886.3
Macaca mulatta (Rhesus monkey)	CSRP2	XP_001082599.1
Canis lupus familiaris (dog)	LOC475409	XP_005629483.1
Bos taurus (cattle)	CSRP2	NP_001033272.1
Mus musculus (house mouse)	Csrp2	NP_031818.3
Gallus gallus (chicken)	CSRP2	NP_990539.1
Drosophila melanogaster (fruit fly)	Mlp84B	NP_477122.1
Xenopus tropicalis (tropical clawed frog)	csrp2	NP_001016615.1
Rattus norvegicus (Norway rat)	Csrp2	NP_803174.2
Caenorhabditis elegans (roundworm)	mlp-1	NP_498301.2
Homo sapiens (human)	CSRP2	NP_001312.1
Pan troglodytes (chimpanzee)	CSRP2	XP_003313876.1

Gene Ontology
Bibliography

Related articles in PubMed

Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2.
Hoffmann C, Mao X, Brown-Clay J, Moreau F, Al Absi A, Wurzer H, Sousa B, Schmitt F, Berchem G, Janji B, Thomas C
Scientific reports8(1)10191(2018 07)

Cysteine and glycine-rich protein 2 (CSRP2) transcript levels correlate with leukemia relapse and leukemia-free survival in adults with B-cell acute lymphoblastic leukemia and normal cytogenetics.
Wang SJ, Wang PZ, Gale RP, Qin YZ, Liu YR, Lai YY, Jiang H, Jiang Q, Zhang XH, Jiang B, Xu LP, Huang XJ, Liu KY, Ruan GR
Oncotarget8(22)35984-36000(2017 May)

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.
Kuo JC, Han X, Hsiao CT, Yates JR 3rd, Waterman CM
Nature cell biology13(4)383-93(2011 Apr)

Interleukin-10 activation of the interleukin-10E1 pathway and tissue inhibitor of metalloproteinase-1 expression is enhanced by proteasome inhibitors in primary prostate tumor lines.
Stearns ME, Wang M, Hu Y, Garcia FU
Molecular cancer research : MCR1(9)631-42(2003 Jul)

IL-10/IL-10 receptor signaling regulates TIMP-1 expression in primary human prostate tumor lines.
Wang M, Hu Y, Shima I, Stearns ME
Cancer biology & therapy1(5)556-63(2002 Sep-Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CSRP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CSRP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02869	NM_001321.3 Latest version!	Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu02869	NM_001300965.2 Latest version!	Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu02869	NM_001321.2	Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu02869	NM_001300965.1	Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CSRP2 ( NM_001300965.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001287894.1 Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02869
Clone ID Related Accession (Same CDS sequence)	NM_001300965.1 , NM_001321.3 , NM_001321.2 , NM_001300965.2
Accession Version	NM_001300965.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550851200000
Organism	Homo sapiens(human)
Product	cysteine and glycine-rich protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124784.4, BX461295.2, CN408330.1 and BC000992.2. On Jul 17, 2014 this sequence version replaced XM_005268678.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: CB961771.1, CN408330.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGTCT GGGGAGGTGG AAACAAGTGT GGGGCCTGTG GGAGGACCGT GTACCACGCA 
GAAGAGGTGC AGTGTGATGG CAGGAGCTTC CACCGCTGCT GCTTTCTCTG CATGGTTTGC 
AGGAAAAATT TAGATAGCAC AACAGTGGCA ATTCACGATG AAGAGATCTA CTGCAAATCC 
TGCTACGGAA AGAAGTATGG GCCAAAAGGC TACGGTTATG GCCAGGGCGC TGGCACGCTT 
AACATGGACC GTGGCGAGAG GCTGGGCATC AAACCAGAGA GTGTTCAGCC TCACAGGCCT 
ACAACAAATC CAAACACTTC TAAATTTGCT CAGAAATATG GAGGTGCTGA GAAGTGTTCC 
AGATGTGGGG ATTCTGTATA TGCTGCCGAG AAGATAATTG GAGCTGGAAA GCCCTGGCAC 
AAAAACTGTT TCCGATGTGC AAAGTGTGGG AAGAGTCTTG AATCAACAAC TCTGACTGAA 
AAAGAAGGTG AAATCTATTG TAAAGGATGC TATGCAAAGA ACTTTGGGCC CAAGGGATTT 
GGCTATGGCC AAGGAGCAGG GGCTCTTGTT CATGCCCAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001287894.1
CDS	80..661
Translation	MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGFGYGQGAGALVHAQ

Target ORF information:

RefSeq Version	NM_001300965.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001300965.1

ORF Insert Sequence:

ATGCCTGTCT GGGGAGGTGG AAACAAGTGT GGGGCCTGTG GGAGGACCGT GTACCACGCA 
GAAGAGGTGC AGTGTGATGG CAGGAGCTTC CACCGCTGCT GCTTTCTCTG CATGGTTTGC 
AGGAAAAATT TAGATAGCAC AACAGTGGCA ATTCACGATG AAGAGATCTA CTGCAAATCC 
TGCTACGGAA AGAAGTATGG GCCAAAAGGC TACGGTTATG GCCAGGGCGC TGGCACGCTT 
AACATGGACC GTGGCGAGAG GCTGGGCATC AAACCAGAGA GTGTTCAGCC TCACAGGCCT 
ACAACAAATC CAAACACTTC TAAATTTGCT CAGAAATATG GAGGTGCTGA GAAGTGTTCC 
AGATGTGGGG ATTCTGTATA TGCTGCCGAG AAGATAATTG GAGCTGGAAA GCCCTGGCAC 
AAAAACTGTT TCCGATGTGC AAAGTGTGGG AAGAGTCTTG AATCAACAAC TCTGACTGAA 
AAAGAAGGTG AAATCTATTG TAAAGGATGC TATGCAAAGA ACTTTGGGCC CAAGGGATTT 
GGCTATGGCC AAGGAGCAGG GGCTCTTGTT CATGCCCAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSRP2 ( NM_001321.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001312.1 Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02869
Clone ID Related Accession (Same CDS sequence)	NM_001300965.1 , NM_001321.3 , NM_001321.2 , NM_001300965.2
Accession Version	NM_001321.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1572796800000
Organism	Homo sapiens(human)
Product	cysteine and glycine-rich protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX461295.2, BC000992.2 and AC124784.4. On Nov 23, 2018 this sequence version replaced NM_001321.2. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.172419.1, SRR5189652.173068.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000311083.10/ ENSP00000310901.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCTGTCT GGGGAGGTGG AAACAAGTGT GGGGCCTGTG GGAGGACCGT GTACCACGCA 
GAAGAGGTGC AGTGTGATGG CAGGAGCTTC CACCGCTGCT GCTTTCTCTG CATGGTTTGC 
AGGAAAAATT TAGATAGCAC AACAGTGGCA ATTCACGATG AAGAGATCTA CTGCAAATCC 
TGCTACGGAA AGAAGTATGG GCCAAAAGGC TACGGTTATG GCCAGGGCGC TGGCACGCTT 
AACATGGACC GTGGCGAGAG GCTGGGCATC AAACCAGAGA GTGTTCAGCC TCACAGGCCT 
ACAACAAATC CAAACACTTC TAAATTTGCT CAGAAATATG GAGGTGCTGA GAAGTGTTCC 
AGATGTGGGG ATTCTGTATA TGCTGCCGAG AAGATAATTG GAGCTGGAAA GCCCTGGCAC 
AAAAACTGTT TCCGATGTGC AAAGTGTGGG AAGAGTCTTG AATCAACAAC TCTGACTGAA 
AAAGAAGGTG AAATCTATTG TAAAGGATGC TATGCAAAGA ACTTTGGGCC CAAGGGATTT 
GGCTATGGCC AAGGAGCAGG GGCTCTTGTT CATGCCCAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001312.1
CDS	84..665
Translation	MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGFGYGQGAGALVHAQ

Target ORF information:

RefSeq Version	NM_001321.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321.3

ORF Insert Sequence:

ATGCCTGTCT GGGGAGGTGG AAACAAGTGT GGGGCCTGTG GGAGGACCGT GTACCACGCA 
GAAGAGGTGC AGTGTGATGG CAGGAGCTTC CACCGCTGCT GCTTTCTCTG CATGGTTTGC 
AGGAAAAATT TAGATAGCAC AACAGTGGCA ATTCACGATG AAGAGATCTA CTGCAAATCC 
TGCTACGGAA AGAAGTATGG GCCAAAAGGC TACGGTTATG GCCAGGGCGC TGGCACGCTT 
AACATGGACC GTGGCGAGAG GCTGGGCATC AAACCAGAGA GTGTTCAGCC TCACAGGCCT 
ACAACAAATC CAAACACTTC TAAATTTGCT CAGAAATATG GAGGTGCTGA GAAGTGTTCC 
AGATGTGGGG ATTCTGTATA TGCTGCCGAG AAGATAATTG GAGCTGGAAA GCCCTGGCAC 
AAAAACTGTT TCCGATGTGC AAAGTGTGGG AAGAGTCTTG AATCAACAAC TCTGACTGAA 
AAAGAAGGTG AAATCTATTG TAAAGGATGC TATGCAAAGA ACTTTGGGCC CAAGGGATTT 
GGCTATGGCC AAGGAGCAGG GGCTCTTGTT CATGCCCAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSRP2 ( NM_001321.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001312.1 Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02869
Clone ID Related Accession (Same CDS sequence)	NM_001300965.1 , NM_001321.3 , NM_001321.2 , NM_001300965.2
Accession Version	NM_001321.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506873600000
Organism	Homo sapiens(human)
Product	cysteine and glycine-rich protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124784.4, BX461295.2 and BC000992.2. On Jul 17, 2014 this sequence version replaced NM_001321.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BI517866.1, CD580514.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGTCT GGGGAGGTGG AAACAAGTGT GGGGCCTGTG GGAGGACCGT GTACCACGCA 
GAAGAGGTGC AGTGTGATGG CAGGAGCTTC CACCGCTGCT GCTTTCTCTG CATGGTTTGC 
AGGAAAAATT TAGATAGCAC AACAGTGGCA ATTCACGATG AAGAGATCTA CTGCAAATCC 
TGCTACGGAA AGAAGTATGG GCCAAAAGGC TACGGTTATG GCCAGGGCGC TGGCACGCTT 
AACATGGACC GTGGCGAGAG GCTGGGCATC AAACCAGAGA GTGTTCAGCC TCACAGGCCT 
ACAACAAATC CAAACACTTC TAAATTTGCT CAGAAATATG GAGGTGCTGA GAAGTGTTCC 
AGATGTGGGG ATTCTGTATA TGCTGCCGAG AAGATAATTG GAGCTGGAAA GCCCTGGCAC 
AAAAACTGTT TCCGATGTGC AAAGTGTGGG AAGAGTCTTG AATCAACAAC TCTGACTGAA 
AAAGAAGGTG AAATCTATTG TAAAGGATGC TATGCAAAGA ACTTTGGGCC CAAGGGATTT 
GGCTATGGCC AAGGAGCAGG GGCTCTTGTT CATGCCCAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001312.1
CDS	105..686
Translation	MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGFGYGQGAGALVHAQ

Target ORF information:

RefSeq Version	NM_001321.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321.2

ORF Insert Sequence:

ATGCCTGTCT GGGGAGGTGG AAACAAGTGT GGGGCCTGTG GGAGGACCGT GTACCACGCA 
GAAGAGGTGC AGTGTGATGG CAGGAGCTTC CACCGCTGCT GCTTTCTCTG CATGGTTTGC 
AGGAAAAATT TAGATAGCAC AACAGTGGCA ATTCACGATG AAGAGATCTA CTGCAAATCC 
TGCTACGGAA AGAAGTATGG GCCAAAAGGC TACGGTTATG GCCAGGGCGC TGGCACGCTT 
AACATGGACC GTGGCGAGAG GCTGGGCATC AAACCAGAGA GTGTTCAGCC TCACAGGCCT 
ACAACAAATC CAAACACTTC TAAATTTGCT CAGAAATATG GAGGTGCTGA GAAGTGTTCC 
AGATGTGGGG ATTCTGTATA TGCTGCCGAG AAGATAATTG GAGCTGGAAA GCCCTGGCAC 
AAAAACTGTT TCCGATGTGC AAAGTGTGGG AAGAGTCTTG AATCAACAAC TCTGACTGAA 
AAAGAAGGTG AAATCTATTG TAAAGGATGC TATGCAAAGA ACTTTGGGCC CAAGGGATTT 
GGCTATGGCC AAGGAGCAGG GGCTCTTGTT CATGCCCAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSRP2 ( NM_001300965.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001287894.1 Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02869
Clone ID Related Accession (Same CDS sequence)	NM_001300965.1 , NM_001321.3 , NM_001321.2 , NM_001300965.2
Accession Version	NM_001300965.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1572796800000
Organism	Homo sapiens(human)
Product	cysteine and glycine-rich protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX461295.2, CN408330.1, BC000992.2 and AC124784.4. On May 31, 2019 this sequence version replaced NM_001300965.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7410570.508188.1, SRR7410570.508230.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGTCT GGGGAGGTGG AAACAAGTGT GGGGCCTGTG GGAGGACCGT GTACCACGCA 
GAAGAGGTGC AGTGTGATGG CAGGAGCTTC CACCGCTGCT GCTTTCTCTG CATGGTTTGC 
AGGAAAAATT TAGATAGCAC AACAGTGGCA ATTCACGATG AAGAGATCTA CTGCAAATCC 
TGCTACGGAA AGAAGTATGG GCCAAAAGGC TACGGTTATG GCCAGGGCGC TGGCACGCTT 
AACATGGACC GTGGCGAGAG GCTGGGCATC AAACCAGAGA GTGTTCAGCC TCACAGGCCT 
ACAACAAATC CAAACACTTC TAAATTTGCT CAGAAATATG GAGGTGCTGA GAAGTGTTCC 
AGATGTGGGG ATTCTGTATA TGCTGCCGAG AAGATAATTG GAGCTGGAAA GCCCTGGCAC 
AAAAACTGTT TCCGATGTGC AAAGTGTGGG AAGAGTCTTG AATCAACAAC TCTGACTGAA 
AAAGAAGGTG AAATCTATTG TAAAGGATGC TATGCAAAGA ACTTTGGGCC CAAGGGATTT 
GGCTATGGCC AAGGAGCAGG GGCTCTTGTT CATGCCCAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001287894.1
CDS	59..640
Translation	MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGFGYGQGAGALVHAQ

Target ORF information:

RefSeq Version	NM_001300965.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine and glycine rich protein 2 (CSRP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001300965.2

ORF Insert Sequence:

ATGCCTGTCT GGGGAGGTGG AAACAAGTGT GGGGCCTGTG GGAGGACCGT GTACCACGCA 
GAAGAGGTGC AGTGTGATGG CAGGAGCTTC CACCGCTGCT GCTTTCTCTG CATGGTTTGC 
AGGAAAAATT TAGATAGCAC AACAGTGGCA ATTCACGATG AAGAGATCTA CTGCAAATCC 
TGCTACGGAA AGAAGTATGG GCCAAAAGGC TACGGTTATG GCCAGGGCGC TGGCACGCTT 
AACATGGACC GTGGCGAGAG GCTGGGCATC AAACCAGAGA GTGTTCAGCC TCACAGGCCT 
ACAACAAATC CAAACACTTC TAAATTTGCT CAGAAATATG GAGGTGCTGA GAAGTGTTCC 
AGATGTGGGG ATTCTGTATA TGCTGCCGAG AAGATAATTG GAGCTGGAAA GCCCTGGCAC 
AAAAACTGTT TCCGATGTGC AAAGTGTGGG AAGAGTCTTG AATCAACAAC TCTGACTGAA 
AAAGAAGGTG AAATCTATTG TAAAGGATGC TATGCAAAGA ACTTTGGGCC CAAGGGATTT 
GGCTATGGCC AAGGAGCAGG GGCTCTTGTT CATGCCCAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2.
Scientific reports8(1)10191(2018 07)
Hoffmann C,Mao X,Brown-Clay J,Moreau F,Al Absi A,Wurzer H,Sousa B,Schmitt F,Berchem G,Janji B,Thomas C

Cysteine and glycine-rich protein 2 (CSRP2) transcript levels correlate with leukemia relapse and leukemia-free survival in adults with B-cell acute lymphoblastic leukemia and normal cytogenetics.
Oncotarget8(22)35984-36000(2017 May)
Wang SJ,Wang PZ,Gale RP,Qin YZ,Liu YR,Lai YY,Jiang H,Jiang Q,Zhang XH,Jiang B,Xu LP,Huang XJ,Liu KY,Ruan GR

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.
Nature cell biology13(4)383-93(2011 Apr)
Kuo JC,Han X,Hsiao CT,Yates JR 3rd,Waterman CM

Interleukin-10 activation of the interleukin-10E1 pathway and tissue inhibitor of metalloproteinase-1 expression is enhanced by proteasome inhibitors in primary prostate tumor lines.
Molecular cancer research : MCR1(9)631-42(2003 Jul)
Stearns ME,Wang M,Hu Y,Garcia FU

IL-10/IL-10 receptor signaling regulates TIMP-1 expression in primary human prostate tumor lines.
Cancer biology & therapy1(5)556-63(2002 Sep-Oct)
Wang M,Hu Y,Shima I,Stearns ME

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CSRP2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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