SDR9C7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SDR9C7
Entrez Gene ID	121214
Full Name	short chain dehydrogenase/reductase family 9C member 7
Synonyms	ARCI13,RDHS,SDR-O,SDRO
General protein information	Preferred Names short chain dehydrogenase/reductase family 9C member 7 Names short-chain dehydrogenase/reductase family 9C member 7 RDH-S orphan short-chain dehydrogenase / reductase orphan short-chain dehydrogenase/reductase retinol dehydrogenase similar protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.3
Summary	This gene encodes a protein with similarity to the short-chain dehydrogenase/reductase (SDR) family but has not been shown to have retinoid or dehydrogenase activities. [provided by RefSeq, Apr 2010].
Disorder MIM:	609769
Disorder Html:	Ichthyosis, congenital, autosomal recessive 13, 617574 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_148897.3	NP_683695.1	short-chain dehydrogenase/reductase family 9C member 7
NM_148897.2	NP_683695.1	short-chain dehydrogenase/reductase family 9C member 7

Pathways from BioSystems

Homologies

Homo sapiens (human)	SDR9C7	NP_683695.1
Macaca mulatta (Rhesus monkey)	LOC100428095	XP_002798684.1
Mus musculus (house mouse)	Sdr9c7	NP_081577.1
Pan troglodytes (chimpanzee)	SDR9C7	XP_522439.2
Canis lupus familiaris (dog)	SDR9C7	XP_538240.2
Bos taurus (cattle)	SDR9C7	NP_001077206.1
Rattus norvegicus (Norway rat)	Sdr9c7	XP_006241577.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of mutations in SDR9C7 in six families with autosomal recessive congenital ichthyosis.
Hotz A, Fagerberg C, Vahlquist A, Bygum A, Törmä H, Rauschendorf MA, Zhang H, Heinz L, Bourrat E, Hausser I, Vestergaard V, Dragomir A, Zimmer AD, Fischer J
The British journal of dermatology178(3)e207-e209(2018 03)

Whole-exome sequencing identified a novel frameshift mutation in SDR9C7 underlying autosomal recessive congenital ichthyosis in a Pakistani family.
Karim N, Murtaza G, Naeem M
The British journal of dermatology177(5)e191-e192(2017 11)

Mutations in SDR9C7 gene encoding an enzyme for vitamin A metabolism underlie autosomal recessive congenital ichthyosis.
Shigehara Y, Okuda S, Nemer G, Chedraoui A, Hayashi R, Bitar F, Nakai H, Abbas O, Daou L, Abe R, Sleiman MB, Kibbi AG, Kurban M, Shimomura Y
Human molecular genetics25(20)4484-4493(2016 10)

SDR9C7 promotes lymph node metastases in patients with esophageal squamous cell carcinoma.
Tang S, Gao L, Bi Q, Xu G, Wang S, Zhao G, Chen Z, Zheng X, Pan Y, Zhao L, Kang J, Yang G, Shi Y, Wu K, Gong T, Fan D
PloS one8(1)e52184(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SDR9C7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SDR9C7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu01970	NM_148897.3 Latest version!	Homo sapiens short chain dehydrogenase/reductase family 9C member 7 (SDR9C7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
View Old Accession Versions >>
OHu01970	NM_148897.2	Homo sapiens short chain dehydrogenase/reductase family 9C member 7 (SDR9C7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SDR9C7 ( NM_148897.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_683695.1 Homo sapiens short chain dehydrogenase/reductase family 9C member 7 (SDR9C7), mRNA.

Price & Availability↑

CloneID	OHu01970
Clone ID Related Accession (Same CDS sequence)	NM_148897.3 , NM_148897.2
Accession Version	NM_148897.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568995200000
Organism	Homo sapiens(human)
Product	short-chain dehydrogenase/reductase family 9C member 7
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC026120.33, AK122782.1 and BC101551.1. On Nov 22, 2018 this sequence version replaced NM_148897.2. ##Evidence-Data-START## Transcript exon combination :: AK122782.1, SRR3476690.1008873.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000293502.2/ ENSP00000293502.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCCC TCACAGACCT CTCATTTATG TATCGCTGGT TCAAGAACTG CAATCTGGTT 
GGCAACCTCT CAGAGAAGTA CGTCTTCATC ACAGGCTGTG ACTCTGGCTT CGGGAACCTG 
CTGGCCAAAC AGCTGGTTGA TCGGGGCATG CAGGTGCTGG CTGCTTGCTT CACTGAGGAG 
GGATCCCAGA AACTTCAGCG GGATACCTCC TATCGGCTGC AGACCACCCT ACTGGATGTC 
ACCAAGAGCG AAAGCATCAA GGCGGCGGCC CAGTGGGTGA GGGACAAAGT GGGCGAACAA 
GGCCTCTGGG CCCTGGTGAA CAATGCTGGT GTGGGCCTGC CCAGTGGTCC CAACGAATGG 
CTGACCAAGG ATGACTTTGT GAAGGTGATT AATGTGAACC TGGTGGGACT GATCGAAGTG 
ACCCTTCACA TGCTGCCCAT GGTCAAGAGA GCCCGGGGCA GGGTTGTCAA CATGTCCAGC 
TCTGGTGGTC GTGTGGCTGT CATTGGTGGT GGCTACTGCG TCTCCAAGTT TGGCGTTGAG 
GCCTTCTCTG ACAGCATAAG GCGTGAGCTC TACTACTTTG GGGTGAAAGT CTGCATCATT 
GAGCCAGGGA ACTATCGGAC AGCCATTCTC GGCAAGGAGA ACCTGGAGTC ACGCATGCGA 
AAGCTTTGGG AGAGGCTGCC TCAGGAGACC CGGGACAGCT ACGGAGAGGA TTATTTCCGC 
ATCTATACTG ACAAGTTAAA AAACATAATG CAGGTGGCAG AGCCCAGAGT CAGAGATGTC 
ATCAACAGCA TGGAGCATGC TATTGTTTCC CGGAGCCCTC GCATCCGCTA CAACCCTGGC 
CTGGATGCCA AACTCCTCTA CATCCCTCTG GCTAAGTTGC CCACCCCTGT GACAGATTTC 
ATCCTAAGCC GGTACCTTCC AAGGCCAGCG GACAGTGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_683695.1
CDS	148..1089
Translation	MAALTDLSFMYRWFKNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTLLDVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQETRDSYGEDYFRIYTDKLKNIMQVAEPRVRDVINSMEHAIVSRSPRIRYNPGLDAKLLYIPLAKLPTPVTDFILSRYLPRPADSV

Target ORF information:

RefSeq Version	NM_148897.3
Organism	Homo sapiens(human)
Definition	Homo sapiens short chain dehydrogenase/reductase family 9C member 7 (SDR9C7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_148897.3

ORF Insert Sequence:

ATGGCGGCCC TCACAGACCT CTCATTTATG TATCGCTGGT TCAAGAACTG CAATCTGGTT 
GGCAACCTCT CAGAGAAGTA CGTCTTCATC ACAGGCTGTG ACTCTGGCTT CGGGAACCTG 
CTGGCCAAAC AGCTGGTTGA TCGGGGCATG CAGGTGCTGG CTGCTTGCTT CACTGAGGAG 
GGATCCCAGA AACTTCAGCG GGATACCTCC TATCGGCTGC AGACCACCCT ACTGGATGTC 
ACCAAGAGCG AAAGCATCAA GGCGGCGGCC CAGTGGGTGA GGGACAAAGT GGGCGAACAA 
GGCCTCTGGG CCCTGGTGAA CAATGCTGGT GTGGGCCTGC CCAGTGGTCC CAACGAATGG 
CTGACCAAGG ATGACTTTGT GAAGGTGATT AATGTGAACC TGGTGGGACT GATCGAAGTG 
ACCCTTCACA TGCTGCCCAT GGTCAAGAGA GCCCGGGGCA GGGTTGTCAA CATGTCCAGC 
TCTGGTGGTC GTGTGGCTGT CATTGGTGGT GGCTACTGCG TCTCCAAGTT TGGCGTTGAG 
GCCTTCTCTG ACAGCATAAG GCGTGAGCTC TACTACTTTG GGGTGAAAGT CTGCATCATT 
GAGCCAGGGA ACTATCGGAC AGCCATTCTC GGCAAGGAGA ACCTGGAGTC ACGCATGCGA 
AAGCTTTGGG AGAGGCTGCC TCAGGAGACC CGGGACAGCT ACGGAGAGGA TTATTTCCGC 
ATCTATACTG ACAAGTTAAA AAACATAATG CAGGTGGCAG AGCCCAGAGT CAGAGATGTC 
ATCAACAGCA TGGAGCATGC TATTGTTTCC CGGAGCCCTC GCATCCGCTA CAACCCTGGC 
CTGGATGCCA AACTCCTCTA CATCCCTCTG GCTAAGTTGC CCACCCCTGT GACAGATTTC 
ATCCTAAGCC GGTACCTTCC AAGGCCAGCG GACAGTGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SDR9C7 ( NM_148897.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_683695.1 Homo sapiens short chain dehydrogenase/reductase family 9C member 7 (SDR9C7), mRNA.

Price & Availability↑

CloneID	OHu01970
Clone ID Related Accession (Same CDS sequence)	NM_148897.3 , NM_148897.2
Accession Version	NM_148897.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	short-chain dehydrogenase/reductase family 9C member 7
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK122782.1, BC101551.1 and AC026120.33. On Apr 22, 2010 this sequence version replaced NM_148897.1. ##Evidence-Data-START## Transcript exon combination :: AK122782.1, BC101551.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCCC TCACAGACCT CTCATTTATG TATCGCTGGT TCAAGAACTG CAATCTGGTT 
GGCAACCTCT CAGAGAAGTA CGTCTTCATC ACAGGCTGTG ACTCTGGCTT CGGGAACCTG 
CTGGCCAAAC AGCTGGTTGA TCGGGGCATG CAGGTGCTGG CTGCTTGCTT CACTGAGGAG 
GGATCCCAGA AACTTCAGCG GGATACCTCC TATCGGCTGC AGACCACCCT ACTGGATGTC 
ACCAAGAGCG AAAGCATCAA GGCGGCGGCC CAGTGGGTGA GGGACAAAGT GGGCGAACAA 
GGCCTCTGGG CCCTGGTGAA CAATGCTGGT GTGGGCCTGC CCAGTGGTCC CAACGAATGG 
CTGACCAAGG ATGACTTTGT GAAGGTGATT AATGTGAACC TGGTGGGACT GATCGAAGTG 
ACCCTTCACA TGCTGCCCAT GGTCAAGAGA GCCCGGGGCA GGGTTGTCAA CATGTCCAGC 
TCTGGTGGTC GTGTGGCTGT CATTGGTGGT GGCTACTGCG TCTCCAAGTT TGGCGTTGAG 
GCCTTCTCTG ACAGCATAAG GCGTGAGCTC TACTACTTTG GGGTGAAAGT CTGCATCATT 
GAGCCAGGGA ACTATCGGAC AGCCATTCTC GGCAAGGAGA ACCTGGAGTC ACGCATGCGA 
AAGCTTTGGG AGAGGCTGCC TCAGGAGACC CGGGACAGCT ACGGAGAGGA TTATTTCCGC 
ATCTATACTG ACAAGTTAAA AAACATAATG CAGGTGGCAG AGCCCAGAGT CAGAGATGTC 
ATCAACAGCA TGGAGCATGC TATTGTTTCC CGGAGCCCTC GCATCCGCTA CAACCCTGGC 
CTGGATGCCA AACTCCTCTA CATCCCTCTG GCTAAGTTGC CCACCCCTGT GACAGATTTC 
ATCCTAAGCC GGTACCTTCC AAGGCCAGCG GACAGTGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_683695.1
CDS	145..1086
Translation	MAALTDLSFMYRWFKNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTLLDVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQETRDSYGEDYFRIYTDKLKNIMQVAEPRVRDVINSMEHAIVSRSPRIRYNPGLDAKLLYIPLAKLPTPVTDFILSRYLPRPADSV

Target ORF information:

RefSeq Version	NM_148897.2
Organism	Homo sapiens(human)
Definition	Homo sapiens short chain dehydrogenase/reductase family 9C member 7 (SDR9C7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_148897.2

ORF Insert Sequence:

ATGGCGGCCC TCACAGACCT CTCATTTATG TATCGCTGGT TCAAGAACTG CAATCTGGTT 
GGCAACCTCT CAGAGAAGTA CGTCTTCATC ACAGGCTGTG ACTCTGGCTT CGGGAACCTG 
CTGGCCAAAC AGCTGGTTGA TCGGGGCATG CAGGTGCTGG CTGCTTGCTT CACTGAGGAG 
GGATCCCAGA AACTTCAGCG GGATACCTCC TATCGGCTGC AGACCACCCT ACTGGATGTC 
ACCAAGAGCG AAAGCATCAA GGCGGCGGCC CAGTGGGTGA GGGACAAAGT GGGCGAACAA 
GGCCTCTGGG CCCTGGTGAA CAATGCTGGT GTGGGCCTGC CCAGTGGTCC CAACGAATGG 
CTGACCAAGG ATGACTTTGT GAAGGTGATT AATGTGAACC TGGTGGGACT GATCGAAGTG 
ACCCTTCACA TGCTGCCCAT GGTCAAGAGA GCCCGGGGCA GGGTTGTCAA CATGTCCAGC 
TCTGGTGGTC GTGTGGCTGT CATTGGTGGT GGCTACTGCG TCTCCAAGTT TGGCGTTGAG 
GCCTTCTCTG ACAGCATAAG GCGTGAGCTC TACTACTTTG GGGTGAAAGT CTGCATCATT 
GAGCCAGGGA ACTATCGGAC AGCCATTCTC GGCAAGGAGA ACCTGGAGTC ACGCATGCGA 
AAGCTTTGGG AGAGGCTGCC TCAGGAGACC CGGGACAGCT ACGGAGAGGA TTATTTCCGC 
ATCTATACTG ACAAGTTAAA AAACATAATG CAGGTGGCAG AGCCCAGAGT CAGAGATGTC 
ATCAACAGCA TGGAGCATGC TATTGTTTCC CGGAGCCCTC GCATCCGCTA CAACCCTGGC 
CTGGATGCCA AACTCCTCTA CATCCCTCTG GCTAAGTTGC CCACCCCTGT GACAGATTTC 
ATCCTAAGCC GGTACCTTCC AAGGCCAGCG GACAGTGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of mutations in SDR9C7 in six families with autosomal recessive congenital ichthyosis.
The British journal of dermatology178(3)e207-e209(2018 03)
Hotz A,Fagerberg C,Vahlquist A,Bygum A,Törmä H,Rauschendorf MA,Zhang H,Heinz L,Bourrat E,Hausser I,Vestergaard V,Dragomir A,Zimmer AD,Fischer J

Whole-exome sequencing identified a novel frameshift mutation in SDR9C7 underlying autosomal recessive congenital ichthyosis in a Pakistani family.
The British journal of dermatology177(5)e191-e192(2017 11)
Karim N,Murtaza G,Naeem M

Mutations in SDR9C7 gene encoding an enzyme for vitamin A metabolism underlie autosomal recessive congenital ichthyosis.
Human molecular genetics25(20)4484-4493(2016 10)
Shigehara Y,Okuda S,Nemer G,Chedraoui A,Hayashi R,Bitar F,Nakai H,Abbas O,Daou L,Abe R,Sleiman MB,Kibbi AG,Kurban M,Shimomura Y

SDR9C7 promotes lymph node metastases in patients with esophageal squamous cell carcinoma.
PloS one8(1)e52184(2013)
Tang S,Gao L,Bi Q,Xu G,Wang S,Zhao G,Chen Z,Zheng X,Pan Y,Zhao L,Kang J,Yang G,Shi Y,Wu K,Gong T,Fan D

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SDR9C7 cDNA ORF clone, Homo sapiens(human)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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