roraa cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	roraa
Entrez Gene ID	564951
Full Name	RAR-related orphan receptor A, paralog a
Synonyms	RORalpha-B,gb:dq017624,rora2
General protein information	Preferred Names RAR-related orphan receptor A, paralog a Names nuclear receptor ROR-alpha NR1F1-B retinoid-related orphan receptor alpha 2 rora
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017354088.2	XP_017209577.1	nuclear receptor ROR-alpha isoform X1
XM_017354088.1	XP_017209577.1	nuclear receptor ROR-alpha isoform X1
NM_001110167.1	NP_001103637.1	nuclear receptor ROR-alpha A

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	RORA	XP_001100971.2
Gallus gallus (chicken)	RORA	XP_413763.3
Canis lupus familiaris (dog)	RORA	XP_535503.3
Pan troglodytes (chimpanzee)	RORA	XP_001173408.1
Bos taurus (cattle)	RORA	NP_001179790.1
Rattus norvegicus (Norway rat)	Rora	NP_001100304.1
Homo sapiens (human)	RORA	NP_599023.1
Mus musculus (house mouse)	Rora	NP_038674.1
Danio rerio (zebrafish)	roraa	NP_001103637.1

Gene Ontology
Bibliography

Related articles in PubMed

Dual Molecular Effects of Dominant RORA Mutations Cause Two Variants of Syndromic Intellectual Disability with Either Autism or Cerebellar Ataxia.
Guissart C, Latypova X, Rollier P, Khan TN, Stamberger H, McWalter K, Cho MT, Kjaergaard S, Weckhuysen S, Lesca G, Besnard T, Õunap K, Schema L, Chiocchetti AG, McDonald M, de Bellescize J, Vincent M, Van Esch H, Sattler S, Forghani I, Thiffault I, Freitag CM, Barbouth DS, Cadieux-Dion M, Willaert R, Guillen Sacoto MJ, Safina NP, Dubourg C, Grote L, Carré W, Saunders C, Pajusalu S, Farrow E, Boland A, Karlowicz DH, Deleuze JF, Wojcik MH, Pressman R, Isidor B, Vogels A, Van Paesschen W, Al-Gazali L, Al Shamsi AM, Claustres M, Pujol A, Sanders SJ, Rivier F, Leboucq N, Cogné B, Sasorith S, Sanlaville D, Retterer K, Odent S, Katsanis N, Bézieau S, Koenig M, Davis EE, Pasquier L, Küry S
American journal of human genetics102(5)744-759(2018 05)

The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erbα and indirectly via Cebpb/(C/ebpβ) in zebrafish.
Huang G, Zhang F, Ye Q, Wang H
Autophagy12(8)1292-309(2016 08)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons.
Braasch I, Gehrke AR, Smith JJ, Kawasaki K, Manousaki T, Pasquier J, Amores A, Desvignes T, Batzel P, Catchen J, Berlin AM, Campbell MS, Barrell D, Martin KJ, Mulley JF, Ravi V, Lee AP, Nakamura T, Chalopin D, Fan S, Wcisel D, Cañestro C, Sydes J, Beaudry FE, Sun Y, Hertel J, Beam MJ, Fasold M, Ishiyama M, Johnson J, Kehr S, Lara M, Letaw JH, Litman GW, Litman RT, Mikami M, Ota T, Saha NR, Williams L, Stadler PF, Wang H, Taylor JS, Fontenot Q, Ferrara A, Searle SM, Aken B, Yandell M, Schneider I, Yoder JA, Volff JN, Meyer A, Amemiya CT, Venkatesh B, Holland PW, Guiguen Y, Bobe J, Shubin NH, Di Palma F, Alföldi J, Lindblad-Toh K, Postlethwait JH
Nature genetics48(4)427-37(2016 Apr)

Th17 master transcription factors RORα and RORγ regulate the expression of IL-17C, IL-17D and IL-17F in Cynoglossus semilaevis.
Chi H, Bøgwald J, Dalmo RA, Zhang W, Hu YH
Developmental and comparative immunology55169-78(2016 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following roraa gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the roraa cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa31196	NM_001110167.1 Latest version!	Danio rerio RAR-related orphan receptor A, paralog a (roraa), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ODa57805	XM_017354088.2 Latest version!	Danio rerio RAR-related orphan receptor A, paralog a (roraa), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
ODa57805	XM_017354088.1	Danio rerio RAR-related orphan receptor A, paralog a (roraa), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

roraa ( NM_001110167.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001103637.1 Danio rerio RAR-related orphan receptor A, paralog a (roraa), mRNA.

Price & Availability↑

CloneID	ODa31196
Clone ID Related Accession (Same CDS sequence)	NM_001110167.1
Accession Version	NM_001110167.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1407bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Danio rerio(zebrafish)
Product	nuclear receptor ROR-alpha A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB298802.1. On Jan 2, 2008 this sequence version replaced XM_688271.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB298802.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505387 [ECO:0000348] ##Evidence-Data-END##

ATGATGTATT TTGTGATTTC AGCTATGAAA GCTCAAATCG AAATAATTCC CTGCAAGATC 
TGTGGAGACA AATCATCAGG CATCCATTAT GGCGTGATAA CGTGCGAGGG CTGCAAGGGC 
TTCTTCAGGA GGAGTCAGCA GAGCAATGCG GCGTACTCGT GCCCGCGTCA GAAGAACTGC 
CTGATTGACC GCACCAGCCG GAACCGCTGC CAGCACTGCA GGCTGCAGAA GTGTCTGGCC 
GTGGGCATGT CACGTGACGC GGTGAAGTTT GGCCGAATGT CAAAGAAACA GCGGGACAGC 
CTGTATGCGG AAGTGCAGAA ACACCGGCTA CAGCAGCAGC AGCGGGACCA CCAGCAGCAG 
CCCGGTGAAG CCGAACCCCT TACCCCAACT TATGGCCTCT CCACCAATGG TCTGACCGAG 
CTCCACGATG ATCTGAGTGG ATACATGAAT GGCCACACGC CGGATGGCAC CAAGCCTGAC 
TCAGGAGTCA GCAGCTTCTA CCTGGACATC CAACCCTCAC CTGATCAATC CGGCCTGGAC 
ATCAATGGCA TCAAGCCAGA GCCCATCTGC GACTTTACCC CTGGCTCAGG CTTCTTCCCC 
TACTGCTCCT TCACCAATGG GGAGACGTCC CCCACCGTTT CCATGGCTGA GTTGGAACAT 
CTGGCCCAGA ACATTTCCAA GTCCCACATG GAGACGTGTC AGTACCTGAG AGAAGAACTT 
CAGCAGATGA CCTGGCAGGC GTTCCTTCAG GAGGAGGTGG AGAACTACCA GAGCAAGCCC 
AGGGAAGTCA TGTGGCAGTT GTGTGCCATC AAAATCACAG AGGCCATTCA GTATGTGGTG 
GAGTTTGCCA AGCACATCGA CGGCTTCATG GAGCTCTGTC AGAATGATCA GATAGTGCTT 
CTCAAAGCAG GCTCTTTGGA GGTGGTGTTC GTCAGAATGT GCCGTGCCTT CGACCCTCAG 
AACAACACAG TCTATTTCGA TGGAAAGTAT GCCGGGCCTG ATGTCTTTAA ATCATTAGGC 
TGCGACGACT TGATCAGCTC TGTCTTCGAG TTTGGGAAAA ACTTGTGTTC TATGCACCTC 
TCTGAAGACG AGATCGCCCT GTTCTCCGCC TTCGTCTTGA TGTCTGCCGA CCGATCCTGG 
CTCCAGGAGA AGGTGAAGGT GGAGAAACTC CAGCAGAAGA TCCAGCTGGC CCTCCAACAT 
GTTCTGCAGA AAAACCACAG AGAGGACGGC ATACTGACAA AGTTGATATG CAAAGTGTCC 
ACGCTGCGAG CCCTGTGCAG CCGGCATACG GAAAAGCTGA CGGCGTTCAA AGCAATATAC 
CCAGACATTG TCCGCGCACA TTTCCCCCCT TTGTACAAGG AGTTATTCGG ATCGGACTTT 
GAGCAGTCGA TGCCCGTTGA CGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001103637.1
CDS	74..1480
Translation	MMYFVISAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRLQQQQRDHQQQPGEAEPLTPTYGLSTNGLTELHDDLSGYMNGHTPDGTKPDSGVSSFYLDIQPSPDQSGLDINGIKPEPICDFTPGSGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQMTWQAFLQEEVENYQSKPREVMWQLCAIKITEAIQYVVEFAKHIDGFMELCQNDQIVLLKAGSLEVVFVRMCRAFDPQNNTVYFDGKYAGPDVFKSLGCDDLISSVFEFGKNLCSMHLSEDEIALFSAFVLMSADRSWLQEKVKVEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCSRHTEKLTAFKAIYPDIVRAHFPPLYKELFGSDFEQSMPVDG

Target ORF information:

RefSeq Version	NM_001110167.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio RAR-related orphan receptor A, paralog a (roraa), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001110167.1

ORF Insert Sequence:

ATGATGTATT TTGTGATTTC AGCTATGAAA GCTCAAATCG AAATAATTCC CTGCAAGATC 
TGTGGAGACA AATCATCAGG CATCCATTAT GGCGTGATAA CGTGCGAGGG CTGCAAGGGC 
TTCTTCAGGA GGAGTCAGCA GAGCAATGCG GCGTACTCGT GCCCGCGTCA GAAGAACTGC 
CTGATTGACC GCACCAGCCG GAACCGCTGC CAGCACTGCA GGCTGCAGAA GTGTCTGGCC 
GTGGGCATGT CACGTGACGC GGTGAAGTTT GGCCGAATGT CAAAGAAACA GCGGGACAGC 
CTGTATGCGG AAGTGCAGAA ACACCGGCTA CAGCAGCAGC AGCGGGACCA CCAGCAGCAG 
CCCGGTGAAG CCGAACCCCT TACCCCAACT TATGGCCTCT CCACCAATGG TCTGACCGAG 
CTCCACGATG ATCTGAGTGG ATACATGAAT GGCCACACGC CGGATGGCAC CAAGCCTGAC 
TCAGGAGTCA GCAGCTTCTA CCTGGACATC CAACCCTCAC CTGATCAATC CGGCCTGGAC 
ATCAATGGCA TCAAGCCAGA GCCCATCTGC GACTTTACCC CTGGCTCAGG CTTCTTCCCC 
TACTGCTCCT TCACCAATGG GGAGACGTCC CCCACCGTTT CCATGGCTGA GTTGGAACAT 
CTGGCCCAGA ACATTTCCAA GTCCCACATG GAGACGTGTC AGTACCTGAG AGAAGAACTT 
CAGCAGATGA CCTGGCAGGC GTTCCTTCAG GAGGAGGTGG AGAACTACCA GAGCAAGCCC 
AGGGAAGTCA TGTGGCAGTT GTGTGCCATC AAAATCACAG AGGCCATTCA GTATGTGGTG 
GAGTTTGCCA AGCACATCGA CGGCTTCATG GAGCTCTGTC AGAATGATCA GATAGTGCTT 
CTCAAAGCAG GCTCTTTGGA GGTGGTGTTC GTCAGAATGT GCCGTGCCTT CGACCCTCAG 
AACAACACAG TCTATTTCGA TGGAAAGTAT GCCGGGCCTG ATGTCTTTAA ATCATTAGGC 
TGCGACGACT TGATCAGCTC TGTCTTCGAG TTTGGGAAAA ACTTGTGTTC TATGCACCTC 
TCTGAAGACG AGATCGCCCT GTTCTCCGCC TTCGTCTTGA TGTCTGCCGA CCGATCCTGG 
CTCCAGGAGA AGGTGAAGGT GGAGAAACTC CAGCAGAAGA TCCAGCTGGC CCTCCAACAT 
GTTCTGCAGA AAAACCACAG AGAGGACGGC ATACTGACAA AGTTGATATG CAAAGTGTCC 
ACGCTGCGAG CCCTGTGCAG CCGGCATACG GAAAAGCTGA CGGCGTTCAA AGCAATATAC 
CCAGACATTG TCCGCGCACA TTTCCCCCCT TTGTACAAGG AGTTATTCGG ATCGGACTTT 
GAGCAGTCGA TGCCCGTTGA CGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

roraa ( XM_017354088.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_017209577.1 Danio rerio RAR-related orphan receptor A, paralog a (roraa), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa57805
Clone ID Related Accession (Same CDS sequence)	XM_017354088.2 , XM_017354088.1
Accession Version	XM_017354088.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1497369600000
Organism	Danio rerio(zebrafish)
Product	nuclear receptor ROR-alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007136.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XM_017354088.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTCCC CTCCAGATCC AGCGAGCGAC CCGGGCAACG GCGTCTCAGA GCCGGTTACC 
CCGGTCAGGG AAACCCCGGT AAACCTGGAG ACCCTCCGCA AAGCTGAGCA CCAAGCCCCG 
GTGCGCCGGC AGAGCTGCTC CAGCACCAAC AGAGGTATTT CAGTAACAAA GAAGACACAC 
ACCTCTCAAA TCGAAATAAT TCCCTGCAAG ATCTGTGGAG ACAAATCATC AGGCATCCAT 
TATGGCGTGA TAACGTGCGA GGGCTGCAAG GGCTTCTTCA GGAGGAGTCA GCAGAGCAAT 
GCGGCGTACT CGTGCCCGCG TCAGAAGAAC TGCCTGATTG ACCGCACCAG CCGGAACCGC 
TGCCAGCACT GCAGGCTGCA GAAGTGTCTG GCCGTGGGCA TGTCACGTGA CGCGGTGAAG 
TTTGGCCGAA TGTCAAAGAA ACAGCGGGAC AGCCTGTATG CGGAAGTGCA GAAACACCGG 
CTACAGCAGC AGCAGCGGGA CCACCAGCAG CAGCCCGGTG AAGCCGAACC CCTTACCCCA 
ACTTATGGCC TCTCCACCAA TGGTCTGACC GAGCTCCACG ATGATCTGAG TGGATACATG 
AATGGCCACA CGCCGGATGG CACCAAGCCT GACTCAGGAG TCAGCAGCTT CTACCTGGAC 
ATCCAACCCT CACCTGATCA ATCCGGCCTG GACATCAATG GCATCAAGCC AGAGCCCATC 
TGCGACTTTA CCCCTGGCTC AGGCTTCTTC CCCTACTGCT CCTTCACCAA TGGGGAGACG 
TCCCCCACCG TTTCCATGGC TGAGTTGGAA CATCTGGCCC AGAACATTTC CAAGTCCCAC 
ATGGAGACGT GTCAGTACCT GAGAGAAGAA CTTCAGCAGA TGACCTGGCA GGCGTTCCTT 
CAGGAGGAGG TGGAGAACTA CCAGAGCAAG CCCAGGGAAG TCATGTGGCA GTTGTGTGCC 
ATCAAAATCA CAGAGGCCAT TCAGTATGTG GTGGAGTTTG CCAAGCGCAT CGACGGCTTC 
ATGGAGCTCT GTCAGAATGA TCAGATAGTG CTTCTCAAAG CAGGCTCTTT GGAGGTGGTG 
TTCGTCAGAA TGTGCCGTGC CTTCGACCCT CAGAACAACA CAGTCTATTT CGATGGAAAG 
TATGCCGGGC CTGATGTCTT TAAATCATTA GGCTGCGACG ACTTGATCAG CTCTGTCTTC 
GAGTTTGGGA AAAACTTGTG TTCTATGCAC CTCTCTGAAG ACGAGATCGC CCTGTTCTCC 
GCCTTCGTCT TGATGTCTGC CGACCGATCC TGGCTCCAGG AGAAGGTGAA GGTGGAGAAA 
CTCCAGCAGA AGATCCAGCT GGCCCTCCAA CATGTTCTGC AGAAAAACCA CAGAGAGGAC 
GGCATACTGA CAAAGTTGAT ATGCAAAGTG TCCACGCTGC GAGCCCTGTG CAGCCGGCAT 
ACGGAAAAGC TGACGGCGTT CAAAGCAATA TACCCAGACA TTGTCCGCGC ACATTTCCCC 
CCTTTGTACA AGGAGTTATT CGGATCGGAC TTTGAGCAGT CGATGCCCGT TGACGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017209577.1
CDS	211..1770
Translation	MESPPDPASDPGNGVSEPVTPVRETPVNLETLRKAEHQAPVRRQSCSSTNRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRLQQQQRDHQQQPGEAEPLTPTYGLSTNGLTELHDDLSGYMNGHTPDGTKPDSGVSSFYLDIQPSPDQSGLDINGIKPEPICDFTPGSGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQMTWQAFLQEEVENYQSKPREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFVRMCRAFDPQNNTVYFDGKYAGPDVFKSLGCDDLISSVFEFGKNLCSMHLSEDEIALFSAFVLMSADRSWLQEKVKVEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCSRHTEKLTAFKAIYPDIVRAHFPPLYKELFGSDFEQSMPVDG

Target ORF information:

RefSeq Version	XM_017354088.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio RAR-related orphan receptor A, paralog a (roraa), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017354088.2

ORF Insert Sequence:

ATGGAGTCCC CTCCAGATCC AGCGAGCGAC CCGGGCAACG GCGTCTCAGA GCCGGTTACC 
CCGGTCAGGG AAACCCCGGT AAACCTGGAG ACCCTCCGCA AAGCTGAGCA CCAAGCCCCG 
GTGCGCCGGC AGAGCTGCTC CAGCACCAAC AGAGGTATTT CAGTAACAAA GAAGACACAC 
ACCTCTCAAA TCGAAATAAT TCCCTGCAAG ATCTGTGGAG ACAAATCATC AGGCATCCAT 
TATGGCGTGA TAACGTGCGA GGGCTGCAAG GGCTTCTTCA GGAGGAGTCA GCAGAGCAAT 
GCGGCGTACT CGTGCCCGCG TCAGAAGAAC TGCCTGATTG ACCGCACCAG CCGGAACCGC 
TGCCAGCACT GCAGGCTGCA GAAGTGTCTG GCCGTGGGCA TGTCACGTGA CGCGGTGAAG 
TTTGGCCGAA TGTCAAAGAA ACAGCGGGAC AGCCTGTATG CGGAAGTGCA GAAACACCGG 
CTACAGCAGC AGCAGCGGGA CCACCAGCAG CAGCCCGGTG AAGCCGAACC CCTTACCCCA 
ACTTATGGCC TCTCCACCAA TGGTCTGACC GAGCTCCACG ATGATCTGAG TGGATACATG 
AATGGCCACA CGCCGGATGG CACCAAGCCT GACTCAGGAG TCAGCAGCTT CTACCTGGAC 
ATCCAACCCT CACCTGATCA ATCCGGCCTG GACATCAATG GCATCAAGCC AGAGCCCATC 
TGCGACTTTA CCCCTGGCTC AGGCTTCTTC CCCTACTGCT CCTTCACCAA TGGGGAGACG 
TCCCCCACCG TTTCCATGGC TGAGTTGGAA CATCTGGCCC AGAACATTTC CAAGTCCCAC 
ATGGAGACGT GTCAGTACCT GAGAGAAGAA CTTCAGCAGA TGACCTGGCA GGCGTTCCTT 
CAGGAGGAGG TGGAGAACTA CCAGAGCAAG CCCAGGGAAG TCATGTGGCA GTTGTGTGCC 
ATCAAAATCA CAGAGGCCAT TCAGTATGTG GTGGAGTTTG CCAAGCGCAT CGACGGCTTC 
ATGGAGCTCT GTCAGAATGA TCAGATAGTG CTTCTCAAAG CAGGCTCTTT GGAGGTGGTG 
TTCGTCAGAA TGTGCCGTGC CTTCGACCCT CAGAACAACA CAGTCTATTT CGATGGAAAG 
TATGCCGGGC CTGATGTCTT TAAATCATTA GGCTGCGACG ACTTGATCAG CTCTGTCTTC 
GAGTTTGGGA AAAACTTGTG TTCTATGCAC CTCTCTGAAG ACGAGATCGC CCTGTTCTCC 
GCCTTCGTCT TGATGTCTGC CGACCGATCC TGGCTCCAGG AGAAGGTGAA GGTGGAGAAA 
CTCCAGCAGA AGATCCAGCT GGCCCTCCAA CATGTTCTGC AGAAAAACCA CAGAGAGGAC 
GGCATACTGA CAAAGTTGAT ATGCAAAGTG TCCACGCTGC GAGCCCTGTG CAGCCGGCAT 
ACGGAAAAGC TGACGGCGTT CAAAGCAATA TACCCAGACA TTGTCCGCGC ACATTTCCCC 
CCTTTGTACA AGGAGTTATT CGGATCGGAC TTTGAGCAGT CGATGCCCGT TGACGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

roraa ( XM_017354088.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_017209577.1 Danio rerio RAR-related orphan receptor A, paralog a (roraa), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa57805
Clone ID Related Accession (Same CDS sequence)	XM_017354088.2 , XM_017354088.1
Accession Version	XM_017354088.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466611200000
Organism	Danio rerio(Zebrafish)
Product	nuclear receptor ROR-alpha isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007136.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTCCC CTCCAGATCC AGCGAGCGAC CCGGGCAACG GCGTCTCAGA GCCGGTTACC 
CCGGTCAGGG AAACCCCGGT AAACCTGGAG ACCCTCCGCA AAGCTGAGCA CCAAGCCCCG 
GTGCGCCGGC AGAGCTGCTC CAGCACCAAC AGAGGTATTT CAGTAACAAA GAAGACACAC 
ACCTCTCAAA TCGAAATAAT TCCCTGCAAG ATCTGTGGAG ACAAATCATC AGGCATCCAT 
TATGGCGTGA TAACGTGCGA GGGCTGCAAG GGCTTCTTCA GGAGGAGTCA GCAGAGCAAT 
GCGGCGTACT CGTGCCCGCG TCAGAAGAAC TGCCTGATTG ACCGCACCAG CCGGAACCGC 
TGCCAGCACT GCAGGCTGCA GAAGTGTCTG GCCGTGGGCA TGTCACGTGA CGCGGTGAAG 
TTTGGCCGAA TGTCAAAGAA ACAGCGGGAC AGCCTGTATG CGGAAGTGCA GAAACACCGG 
CTACAGCAGC AGCAGCGGGA CCACCAGCAG CAGCCCGGTG AAGCCGAACC CCTTACCCCA 
ACTTATGGCC TCTCCACCAA TGGTCTGACC GAGCTCCACG ATGATCTGAG TGGATACATG 
AATGGCCACA CGCCGGATGG CACCAAGCCT GACTCAGGAG TCAGCAGCTT CTACCTGGAC 
ATCCAACCCT CACCTGATCA ATCCGGCCTG GACATCAATG GCATCAAGCC AGAGCCCATC 
TGCGACTTTA CCCCTGGCTC AGGCTTCTTC CCCTACTGCT CCTTCACCAA TGGGGAGACG 
TCCCCCACCG TTTCCATGGC TGAGTTGGAA CATCTGGCCC AGAACATTTC CAAGTCCCAC 
ATGGAGACGT GTCAGTACCT GAGAGAAGAA CTTCAGCAGA TGACCTGGCA GGCGTTCCTT 
CAGGAGGAGG TGGAGAACTA CCAGAGCAAG CCCAGGGAAG TCATGTGGCA GTTGTGTGCC 
ATCAAAATCA CAGAGGCCAT TCAGTATGTG GTGGAGTTTG CCAAGCGCAT CGACGGCTTC 
ATGGAGCTCT GTCAGAATGA TCAGATAGTG CTTCTCAAAG CAGGCTCTTT GGAGGTGGTG 
TTCGTCAGAA TGTGCCGTGC CTTCGACCCT CAGAACAACA CAGTCTATTT CGATGGAAAG 
TATGCCGGGC CTGATGTCTT TAAATCATTA GGCTGCGACG ACTTGATCAG CTCTGTCTTC 
GAGTTTGGGA AAAACTTGTG TTCTATGCAC CTCTCTGAAG ACGAGATCGC CCTGTTCTCC 
GCCTTCGTCT TGATGTCTGC CGACCGATCC TGGCTCCAGG AGAAGGTGAA GGTGGAGAAA 
CTCCAGCAGA AGATCCAGCT GGCCCTCCAA CATGTTCTGC AGAAAAACCA CAGAGAGGAC 
GGCATACTGA CAAAGTTGAT ATGCAAAGTG TCCACGCTGC GAGCCCTGTG CAGCCGGCAT 
ACGGAAAAGC TGACGGCGTT CAAAGCAATA TACCCAGACA TTGTCCGCGC ACATTTCCCC 
CCTTTGTACA AGGAGTTATT CGGATCGGAC TTTGAGCAGT CGATGCCCGT TGACGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017209577.1
CDS	251..1810
Translation	MESPPDPASDPGNGVSEPVTPVRETPVNLETLRKAEHQAPVRRQSCSSTNRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRLQQQQRDHQQQPGEAEPLTPTYGLSTNGLTELHDDLSGYMNGHTPDGTKPDSGVSSFYLDIQPSPDQSGLDINGIKPEPICDFTPGSGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQMTWQAFLQEEVENYQSKPREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFVRMCRAFDPQNNTVYFDGKYAGPDVFKSLGCDDLISSVFEFGKNLCSMHLSEDEIALFSAFVLMSADRSWLQEKVKVEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCSRHTEKLTAFKAIYPDIVRAHFPPLYKELFGSDFEQSMPVDG

Target ORF information:

RefSeq Version	XM_017354088.1
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio RAR-related orphan receptor A, paralog a (roraa), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017354088.1

ORF Insert Sequence:

ATGGAGTCCC CTCCAGATCC AGCGAGCGAC CCGGGCAACG GCGTCTCAGA GCCGGTTACC 
CCGGTCAGGG AAACCCCGGT AAACCTGGAG ACCCTCCGCA AAGCTGAGCA CCAAGCCCCG 
GTGCGCCGGC AGAGCTGCTC CAGCACCAAC AGAGGTATTT CAGTAACAAA GAAGACACAC 
ACCTCTCAAA TCGAAATAAT TCCCTGCAAG ATCTGTGGAG ACAAATCATC AGGCATCCAT 
TATGGCGTGA TAACGTGCGA GGGCTGCAAG GGCTTCTTCA GGAGGAGTCA GCAGAGCAAT 
GCGGCGTACT CGTGCCCGCG TCAGAAGAAC TGCCTGATTG ACCGCACCAG CCGGAACCGC 
TGCCAGCACT GCAGGCTGCA GAAGTGTCTG GCCGTGGGCA TGTCACGTGA CGCGGTGAAG 
TTTGGCCGAA TGTCAAAGAA ACAGCGGGAC AGCCTGTATG CGGAAGTGCA GAAACACCGG 
CTACAGCAGC AGCAGCGGGA CCACCAGCAG CAGCCCGGTG AAGCCGAACC CCTTACCCCA 
ACTTATGGCC TCTCCACCAA TGGTCTGACC GAGCTCCACG ATGATCTGAG TGGATACATG 
AATGGCCACA CGCCGGATGG CACCAAGCCT GACTCAGGAG TCAGCAGCTT CTACCTGGAC 
ATCCAACCCT CACCTGATCA ATCCGGCCTG GACATCAATG GCATCAAGCC AGAGCCCATC 
TGCGACTTTA CCCCTGGCTC AGGCTTCTTC CCCTACTGCT CCTTCACCAA TGGGGAGACG 
TCCCCCACCG TTTCCATGGC TGAGTTGGAA CATCTGGCCC AGAACATTTC CAAGTCCCAC 
ATGGAGACGT GTCAGTACCT GAGAGAAGAA CTTCAGCAGA TGACCTGGCA GGCGTTCCTT 
CAGGAGGAGG TGGAGAACTA CCAGAGCAAG CCCAGGGAAG TCATGTGGCA GTTGTGTGCC 
ATCAAAATCA CAGAGGCCAT TCAGTATGTG GTGGAGTTTG CCAAGCGCAT CGACGGCTTC 
ATGGAGCTCT GTCAGAATGA TCAGATAGTG CTTCTCAAAG CAGGCTCTTT GGAGGTGGTG 
TTCGTCAGAA TGTGCCGTGC CTTCGACCCT CAGAACAACA CAGTCTATTT CGATGGAAAG 
TATGCCGGGC CTGATGTCTT TAAATCATTA GGCTGCGACG ACTTGATCAG CTCTGTCTTC 
GAGTTTGGGA AAAACTTGTG TTCTATGCAC CTCTCTGAAG ACGAGATCGC CCTGTTCTCC 
GCCTTCGTCT TGATGTCTGC CGACCGATCC TGGCTCCAGG AGAAGGTGAA GGTGGAGAAA 
CTCCAGCAGA AGATCCAGCT GGCCCTCCAA CATGTTCTGC AGAAAAACCA CAGAGAGGAC 
GGCATACTGA CAAAGTTGAT ATGCAAAGTG TCCACGCTGC GAGCCCTGTG CAGCCGGCAT 
ACGGAAAAGC TGACGGCGTT CAAAGCAATA TACCCAGACA TTGTCCGCGC ACATTTCCCC 
CCTTTGTACA AGGAGTTATT CGGATCGGAC TTTGAGCAGT CGATGCCCGT TGACGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dual Molecular Effects of Dominant RORA Mutations Cause Two Variants of Syndromic Intellectual Disability with Either Autism or Cerebellar Ataxia.
American journal of human genetics102(5)744-759(2018 05)
Guissart C,Latypova X,Rollier P,Khan TN,Stamberger H,McWalter K,Cho MT,Kjaergaard S,Weckhuysen S,Lesca G,Besnard T,Õunap K,Schema L,Chiocchetti AG,McDonald M,de Bellescize J,Vincent M,Van Esch H,Sattler S,Forghani I,Thiffault I,Freitag CM,Barbouth DS,Cadieux-Dion M,Willaert R,Guillen Sacoto MJ,Safina NP,Dubourg C,Grote L,Carré W,Saunders C,Pajusalu S,Farrow E,Boland A,Karlowicz DH,Deleuze JF,Wojcik MH,Pressman R,Isidor B,Vogels A,Van Paesschen W,Al-Gazali L,Al Shamsi AM,Claustres M,Pujol A,Sanders SJ,Rivier F,Leboucq N,Cogné B,Sasorith S,Sanlaville D,Retterer K,Odent S,Katsanis N,Bézieau S,Koenig M,Davis EE,Pasquier L,Küry S

The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erbα and indirectly via Cebpb/(C/ebpβ) in zebrafish.
Autophagy12(8)1292-309(2016 08)
Huang G,Zhang F,Ye Q,Wang H

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons.
Nature genetics48(4)427-37(2016 Apr)
Braasch I,Gehrke AR,Smith JJ,Kawasaki K,Manousaki T,Pasquier J,Amores A,Desvignes T,Batzel P,Catchen J,Berlin AM,Campbell MS,Barrell D,Martin KJ,Mulley JF,Ravi V,Lee AP,Nakamura T,Chalopin D,Fan S,Wcisel D,Cañestro C,Sydes J,Beaudry FE,Sun Y,Hertel J,Beam MJ,Fasold M,Ishiyama M,Johnson J,Kehr S,Lara M,Letaw JH,Litman GW,Litman RT,Mikami M,Ota T,Saha NR,Williams L,Stadler PF,Wang H,Taylor JS,Fontenot Q,Ferrara A,Searle SM,Aken B,Yandell M,Schneider I,Yoder JA,Volff JN,Meyer A,Amemiya CT,Venkatesh B,Holland PW,Guiguen Y,Bobe J,Shubin NH,Di Palma F,Alföldi J,Lindblad-Toh K,Postlethwait JH

Th17 master transcription factors RORα and RORγ regulate the expression of IL-17C, IL-17D and IL-17F in Cynoglossus semilaevis.
Developmental and comparative immunology55169-78(2016 Feb)
Chi H,Bøgwald J,Dalmo RA,Zhang W,Hu YH

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roraa cDNA ORF clone, Danio rerio(zebrafish)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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