sigirr cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	sigirr
Entrez Gene ID	563606
Full Name	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
Synonyms	sc:d148
General protein information	Preferred Names single immunoglobulin and toll-interleukin 1 receptor (TIR) domain Names single Ig IL-1-related receptor
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001098250.1	NP_001091720.1	single Ig IL-1-related receptor precursor
XM_009298036.2	XP_009296311.1	single Ig IL-1-related receptor isoform X1
XM_009298036.3	XP_009296311.1	single Ig IL-1-related receptor isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Sigirr	NP_075546.2
Danio rerio (zebrafish)	sigirr	NP_001091720.1
Homo sapiens (human)	SIGIRR	NP_068577.2
Pan troglodytes (chimpanzee)	SIGIRR	XP_001148349.2
Bos taurus (cattle)	SIGIRR	NP_001075912.1
Rattus norvegicus (Norway rat)	Sigirr	NP_001020058.1
Gallus gallus (chicken)	SIGIRR	NP_001186471.1
Canis lupus familiaris (dog)	SIGIRR	XP_005631765.1
Xenopus tropicalis (tropical clawed frog)	sigirr	XP_002937693.2

Gene Ontology
Bibliography

Related articles in PubMed

Characterization of SIGIRR/IL-1R8 Homolog from Zebrafish Provides New Insights into Its Inhibitory Role in Hepatic Inflammation.
Feng W, Gu YF, Nie L, Guo DY, Xiang LX, Shao JZ
Journal of immunology (Baltimore, Md. : 1950)197(1)151-67(2016 07)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following sigirr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sigirr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa35471	NM_001098250.1 Latest version!	Danio rerio single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ODa44127	XM_009298036.3 Latest version!	Danio rerio single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
ODa44127	XM_009298036.2	Danio rerio single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

sigirr ( NM_001098250.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001091720.1 Danio rerio single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr), mRNA.

Price & Availability↑

CloneID	ODa35471
Clone ID Related Accession (Same CDS sequence)	NM_001098250.1
Accession Version	NM_001098250.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1281bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1542902400000
Organism	Danio rerio(zebrafish)
Product	single Ig IL-1-related receptor precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CU458918.1. On May 29, 2007 this sequence version replaced XM_686967.2. ##Evidence-Data-START## Transcript exon combination :: CU458918.1, JF714479.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGTGGCGCT GTCACTTCAT TCTCTTCCTG ACATGTCTCG CGAACTCTCA TTCTGCAGAT 
TCCCTTTGTG GCAGCTCTCC AGAGTTCAAG CATGATCGAA CACAGTCAGT GTCGAGTACG 
CTTGGTCACA GTGTGGTCCT CACCTGCACG GCCTCCATGG GTTTGAACGG AACAGATTTA 
GATTGTGAAG ACCACCCGGA GTGGATGAAA GACGGCTTAC AGCTCACAAA CCTCACAATT 
TATCCTCAAA ATAGTAAAGA ATGGTATACT GATGATGAGG GTCGCATGGA AAGCAGTGAA 
TTAACTCTAA CCCTGCGAGA TCGGGCTGAT TTTGGAGTGT ATTACTGCAT AGTGAGGAAC 
AGCACAGCAC AATTCACCGT GAAGGAATAT AAGTCCCCCA GTCACACAGG AGCAGTGGTG 
GCTTCAGTGG TTATGTTGGT TGTACTCGCT CTCGCAGCGG TGGTCTATTC CAAGTGCAGA 
CTCAACTTTA AACTGTGGTA TAAGAATATT TACGGAGAGT ATGAGATCAA CGATGGTAAA 
ATGTATGATG CCTACATCTC GTATGTCAAC AATGAGAATG ACAGGAAGTT TGTCAATTTT 
ATCCTGAAGC CACATTTGGA GAACAAGTAC AGTCATAAGC TGTTGCTCAA TGACACAAAC 
ATCCTTCCTG GAGCTGAGCC GTCAGCTGAG CTGCTGATGA ACATAAGCCG ATGTCGAAGG 
TTGATTGTGG TTCTCTCTCA GTCATACCTG GAGCAGGAGT GGTGCACTAC CAATTTTAGA 
CAGGGTTTGT GGCACCTGAT CGAGCTGTCA AGGAAGCCCA TTTTCATTAT ATTTCAGTCC 
CAGCAGAAGC AAATAAGCCA GGACATCAGT CAGCAGCTGA GACAACACCA GCCTTGTATC 
ACTATGATCA CCTGGGGCGC ACATTCCATG ACTCCTTCTT CAGGGTTCTG GAAGGAACTT 
GCACTGGTAA TGCCACGTAA GGTTACGTTT CACAGGGAAT CTGCAGGTGA TCCACAGACT 
TTGTTACAGG GTGATAAAGC TCCCATGCTC ACCCAGCAGC CTGATTACCT GGACTGCAGA 
CTGGACCCCG ATCCGGCAGG AGACCTGGGT TTGCGTTTGC CCATCTACAA GACCCTTCCC 
ACCAAAGCTC CGGTGCTTCC TGCGGCTCCT GGCCCGACAG GTGAAGCAAA ACCTTCAGAG 
ATAGATGTGT CTGACCTTGG TTTGAGGAAC TACTCTGCCC GCAGAGACTT TTACTGCCTG 
GTCACGGATG ATGATTTATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001091720.1
CDS	96..1376
Translation	MWRCHFILFLTCLANSHSADSLCGSSPEFKHDRTQSVSSTLGHSVVLTCTASMGLNGTDLDCEDHPEWMKDGLQLTNLTIYPQNSKEWYTDDEGRMESSELTLTLRDRADFGVYYCIVRNSTAQFTVKEYKSPSHTGAVVASVVMLVVLALAAVVYSKCRLNFKLWYKNIYGEYEINDGKMYDAYISYVNNENDRKFVNFILKPHLENKYSHKLLLNDTNILPGAEPSAELLMNISRCRRLIVVLSQSYLEQEWCTTNFRQGLWHLIELSRKPIFIIFQSQQKQISQDISQQLRQHQPCITMITWGAHSMTPSSGFWKELALVMPRKVTFHRESAGDPQTLLQGDKAPMLTQQPDYLDCRLDPDPAGDLGLRLPIYKTLPTKAPVLPAAPGPTGEAKPSEIDVSDLGLRNYSARRDFYCLVTDDDL

Target ORF information:

RefSeq Version	NM_001098250.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098250.1

ORF Insert Sequence:

ATGTGGCGCT GTCACTTCAT TCTCTTCCTG ACATGTCTCG CGAACTCTCA TTCTGCAGAT 
TCCCTTTGTG GCAGCTCTCC AGAGTTCAAG CATGATCGAA CACAGTCAGT GTCGAGTACG 
CTTGGTCACA GTGTGGTCCT CACCTGCACG GCCTCCATGG GTTTGAACGG AACAGATTTA 
GATTGTGAAG ACCACCCGGA GTGGATGAAA GACGGCTTAC AGCTCACAAA CCTCACAATT 
TATCCTCAAA ATAGTAAAGA ATGGTATACT GATGATGAGG GTCGCATGGA AAGCAGTGAA 
TTAACTCTAA CCCTGCGAGA TCGGGCTGAT TTTGGAGTGT ATTACTGCAT AGTGAGGAAC 
AGCACAGCAC AATTCACCGT GAAGGAATAT AAGTCCCCCA GTCACACAGG AGCAGTGGTG 
GCTTCAGTGG TTATGTTGGT TGTACTCGCT CTCGCAGCGG TGGTCTATTC CAAGTGCAGA 
CTCAACTTTA AACTGTGGTA TAAGAATATT TACGGAGAGT ATGAGATCAA CGATGGTAAA 
ATGTATGATG CCTACATCTC GTATGTCAAC AATGAGAATG ACAGGAAGTT TGTCAATTTT 
ATCCTGAAGC CACATTTGGA GAACAAGTAC AGTCATAAGC TGTTGCTCAA TGACACAAAC 
ATCCTTCCTG GAGCTGAGCC GTCAGCTGAG CTGCTGATGA ACATAAGCCG ATGTCGAAGG 
TTGATTGTGG TTCTCTCTCA GTCATACCTG GAGCAGGAGT GGTGCACTAC CAATTTTAGA 
CAGGGTTTGT GGCACCTGAT CGAGCTGTCA AGGAAGCCCA TTTTCATTAT ATTTCAGTCC 
CAGCAGAAGC AAATAAGCCA GGACATCAGT CAGCAGCTGA GACAACACCA GCCTTGTATC 
ACTATGATCA CCTGGGGCGC ACATTCCATG ACTCCTTCTT CAGGGTTCTG GAAGGAACTT 
GCACTGGTAA TGCCACGTAA GGTTACGTTT CACAGGGAAT CTGCAGGTGA TCCACAGACT 
TTGTTACAGG GTGATAAAGC TCCCATGCTC ACCCAGCAGC CTGATTACCT GGACTGCAGA 
CTGGACCCCG ATCCGGCAGG AGACCTGGGT TTGCGTTTGC CCATCTACAA GACCCTTCCC 
ACCAAAGCTC CGGTGCTTCC TGCGGCTCCT GGCCCGACAG GTGAAGCAAA ACCTTCAGAG 
ATAGATGTGT CTGACCTTGG TTTGAGGAAC TACTCTGCCC GCAGAGACTT TTACTGCCTG 
GTCACGGATG ATGATTTATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

sigirr ( XM_009298036.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_009296311.1 Danio rerio single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa44127
Clone ID Related Accession (Same CDS sequence)	XM_009298036.2 , XM_009298036.3
Accession Version	XM_009298036.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 822bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466611200000
Organism	Danio rerio(Zebrafish)
Product	single Ig IL-1-related receptor isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007136.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_009298036.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCGCT GTCACTTCAT TCTCTTCCTG ACATGTCTCG CGAACTCTCA TTCTGCAGAT 
TCCCTTTGTG GCAGCTCTCC AGAGTTCAAG CATGATCGAA CACAGTCAGT GTCGAGTACG 
CTTGGTCACA GTGTGGTCCT CACCTGCACG GCCTCCATGG GTTTGAACGG AACAGATTTA 
GATTGTGAAG ACCACCCGGA GTGGATGAAA GACGGCTTAC AGCTCACAAA CCTCACAATT 
TATCCTCAAA ATAGTAAAGA ATGGTATACT GATGATGAGG GTCGCATGGA AAGCAGTGAA 
TTAACTCTAA CCCTGCGAGA TCGGGCTGAT TTTGGAGTGT ATTACTGCAT AGTGAGGAAC 
AGCACAGCAC AATTCACCGT GAAGGAATAT AAGTCCCCCA GTCACACAGG AGCAGTGGTG 
GCTTCAGTGG TTATGTTGGT TGTACTCGCT CTCGCAGCGG TGGTCTATTC CAAGTGCAGA 
CTCAACTTTA AACTGTGGTA TAAGAATATT TACGGAGAGT ATGAGATCAA CGATGGTAAA 
ATGTATGATG CCTACATCTC GTATGTCAAC AATGAGAATG ACAGGAAGTT TGTCAATTTT 
ATCCTGAAGC CACATTTGGA GAACAAGTAC AGTCATAAGC TGTTGCTCAA TGACACAAAC 
ATCCTTCCTG GAGCTGAGCC GTCAGCTGAG CTGCTGATGA ACATAAGCCG ATGTCGAAGG 
TTGATTGTGG TTCTCTCTCA GTCATACCTG GAGCAGGAGT GGTGCACTAC CAATTTTAGG 
GGCAGCAGTC TTAGGAGAGA ACCCCAGACT TTTCTCTCCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009296311.1
CDS	90..911
Translation	MWRCHFILFLTCLANSHSADSLCGSSPEFKHDRTQSVSSTLGHSVVLTCTASMGLNGTDLDCEDHPEWMKDGLQLTNLTIYPQNSKEWYTDDEGRMESSELTLTLRDRADFGVYYCIVRNSTAQFTVKEYKSPSHTGAVVASVVMLVVLALAAVVYSKCRLNFKLWYKNIYGEYEINDGKMYDAYISYVNNENDRKFVNFILKPHLENKYSHKLLLNDTNILPGAEPSAELLMNISRCRRLIVVLSQSYLEQEWCTTNFRGSSLRREPQTFLS

Target ORF information:

RefSeq Version	XM_009298036.2
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009298036.2

ORF Insert Sequence:

ATGTGGCGCT GTCACTTCAT TCTCTTCCTG ACATGTCTCG CGAACTCTCA TTCTGCAGAT 
TCCCTTTGTG GCAGCTCTCC AGAGTTCAAG CATGATCGAA CACAGTCAGT GTCGAGTACG 
CTTGGTCACA GTGTGGTCCT CACCTGCACG GCCTCCATGG GTTTGAACGG AACAGATTTA 
GATTGTGAAG ACCACCCGGA GTGGATGAAA GACGGCTTAC AGCTCACAAA CCTCACAATT 
TATCCTCAAA ATAGTAAAGA ATGGTATACT GATGATGAGG GTCGCATGGA AAGCAGTGAA 
TTAACTCTAA CCCTGCGAGA TCGGGCTGAT TTTGGAGTGT ATTACTGCAT AGTGAGGAAC 
AGCACAGCAC AATTCACCGT GAAGGAATAT AAGTCCCCCA GTCACACAGG AGCAGTGGTG 
GCTTCAGTGG TTATGTTGGT TGTACTCGCT CTCGCAGCGG TGGTCTATTC CAAGTGCAGA 
CTCAACTTTA AACTGTGGTA TAAGAATATT TACGGAGAGT ATGAGATCAA CGATGGTAAA 
ATGTATGATG CCTACATCTC GTATGTCAAC AATGAGAATG ACAGGAAGTT TGTCAATTTT 
ATCCTGAAGC CACATTTGGA GAACAAGTAC AGTCATAAGC TGTTGCTCAA TGACACAAAC 
ATCCTTCCTG GAGCTGAGCC GTCAGCTGAG CTGCTGATGA ACATAAGCCG ATGTCGAAGG 
TTGATTGTGG TTCTCTCTCA GTCATACCTG GAGCAGGAGT GGTGCACTAC CAATTTTAGG 
GGCAGCAGTC TTAGGAGAGA ACCCCAGACT TTTCTCTCCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

sigirr ( XM_009298036.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_009296311.1 Danio rerio single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa44127
Clone ID Related Accession (Same CDS sequence)	XM_009298036.2 , XM_009298036.3
Accession Version	XM_009298036.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 822bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1497369600000
Organism	Danio rerio(zebrafish)
Product	single Ig IL-1-related receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007136.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XM_009298036.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCGCT GTCACTTCAT TCTCTTCCTG ACATGTCTCG CGAACTCTCA TTCTGCAGAT 
TCCCTTTGTG GCAGCTCTCC AGAGTTCAAG CATGATCGAA CACAGTCAGT GTCGAGTACG 
CTTGGTCACA GTGTGGTCCT CACCTGCACG GCCTCCATGG GTTTGAACGG AACAGATTTA 
GATTGTGAAG ACCACCCGGA GTGGATGAAA GACGGCTTAC AGCTCACAAA CCTCACAATT 
TATCCTCAAA ATAGTAAAGA ATGGTATACT GATGATGAGG GTCGCATGGA AAGCAGTGAA 
TTAACTCTAA CCCTGCGAGA TCGGGCTGAT TTTGGAGTGT ATTACTGCAT AGTGAGGAAC 
AGCACAGCAC AATTCACCGT GAAGGAATAT AAGTCCCCCA GTCACACAGG AGCAGTGGTG 
GCTTCAGTGG TTATGTTGGT TGTACTCGCT CTCGCAGCGG TGGTCTATTC CAAGTGCAGA 
CTCAACTTTA AACTGTGGTA TAAGAATATT TACGGAGAGT ATGAGATCAA CGATGGTAAA 
ATGTATGATG CCTACATCTC GTATGTCAAC AATGAGAATG ACAGGAAGTT TGTCAATTTT 
ATCCTGAAGC CACATTTGGA GAACAAGTAC AGTCATAAGC TGTTGCTCAA TGACACAAAC 
ATCCTTCCTG GAGCTGAGCC GTCAGCTGAG CTGCTGATGA ACATAAGCCG ATGTCGAAGG 
TTGATTGTGG TTCTCTCTCA GTCATACCTG GAGCAGGAGT GGTGCACTAC CAATTTTAGG 
GGCAGCAGTC TTAGGAGAGA ACCCCAGACT TTTCTCTCCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009296311.1
CDS	134..955
Translation	MWRCHFILFLTCLANSHSADSLCGSSPEFKHDRTQSVSSTLGHSVVLTCTASMGLNGTDLDCEDHPEWMKDGLQLTNLTIYPQNSKEWYTDDEGRMESSELTLTLRDRADFGVYYCIVRNSTAQFTVKEYKSPSHTGAVVASVVMLVVLALAAVVYSKCRLNFKLWYKNIYGEYEINDGKMYDAYISYVNNENDRKFVNFILKPHLENKYSHKLLLNDTNILPGAEPSAELLMNISRCRRLIVVLSQSYLEQEWCTTNFRGSSLRREPQTFLS

Target ORF information:

RefSeq Version	XM_009298036.3
Organism	Danio rerio(zebrafish)
Definition	Danio rerio single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009298036.3

ORF Insert Sequence:

ATGTGGCGCT GTCACTTCAT TCTCTTCCTG ACATGTCTCG CGAACTCTCA TTCTGCAGAT 
TCCCTTTGTG GCAGCTCTCC AGAGTTCAAG CATGATCGAA CACAGTCAGT GTCGAGTACG 
CTTGGTCACA GTGTGGTCCT CACCTGCACG GCCTCCATGG GTTTGAACGG AACAGATTTA 
GATTGTGAAG ACCACCCGGA GTGGATGAAA GACGGCTTAC AGCTCACAAA CCTCACAATT 
TATCCTCAAA ATAGTAAAGA ATGGTATACT GATGATGAGG GTCGCATGGA AAGCAGTGAA 
TTAACTCTAA CCCTGCGAGA TCGGGCTGAT TTTGGAGTGT ATTACTGCAT AGTGAGGAAC 
AGCACAGCAC AATTCACCGT GAAGGAATAT AAGTCCCCCA GTCACACAGG AGCAGTGGTG 
GCTTCAGTGG TTATGTTGGT TGTACTCGCT CTCGCAGCGG TGGTCTATTC CAAGTGCAGA 
CTCAACTTTA AACTGTGGTA TAAGAATATT TACGGAGAGT ATGAGATCAA CGATGGTAAA 
ATGTATGATG CCTACATCTC GTATGTCAAC AATGAGAATG ACAGGAAGTT TGTCAATTTT 
ATCCTGAAGC CACATTTGGA GAACAAGTAC AGTCATAAGC TGTTGCTCAA TGACACAAAC 
ATCCTTCCTG GAGCTGAGCC GTCAGCTGAG CTGCTGATGA ACATAAGCCG ATGTCGAAGG 
TTGATTGTGG TTCTCTCTCA GTCATACCTG GAGCAGGAGT GGTGCACTAC CAATTTTAGG 
GGCAGCAGTC TTAGGAGAGA ACCCCAGACT TTTCTCTCCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Characterization of SIGIRR/IL-1R8 Homolog from Zebrafish Provides New Insights into Its Inhibitory Role in Hepatic Inflammation.
Journal of immunology (Baltimore, Md. : 1950)197(1)151-67(2016 07)
Feng W,Gu YF,Nie L,Guo DY,Xiang LX,Shao JZ

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

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sigirr cDNA ORF clone, Danio rerio(zebrafish)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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