RAP1AB cDNA ORF clone, Danio rerio(Zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	RAP1AB
Entrez Gene ID	406714
Full Name	RAP1A, member of RAS oncogene family b
Synonyms	zgc:56630
General protein information	Preferred Names RAP1A, member of RAS oncogene family b Names ras-related protein Rap-1b-like
Gene Type	protein-coding
Organism	Danio rerio(Zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_021479589.1	XP_021335264.1	ras-related protein Rap-1b-like isoform X1
NM_001243179.1	NP_001230108.1	ras-related protein Rap-1b-like
NM_213405.2	NP_998570.2	ras-related protein Rap-1b-like
XM_021479590.1	XP_021335265.1	ras-related protein Rap-1b-like isoform X1
XM_005155801.2	XP_005155858.1	ras-related protein Rap-1b-like isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	RAP1A	XP_524793.1
Mus musculus (house mouse)	Rap1a	NP_663516.1
Homo sapiens (human)	RAP1A	NP_001010935.1
Danio rerio (zebrafish)	rap1ab	NP_001230108.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001874	XP_003435963.1
Rattus norvegicus (Norway rat)	Rap1a	NP_001005765.1
Drosophila melanogaster (fruit fly)	R	NP_001189023.1
Eremothecium gossypii	AGOS_AFR464W	NP_986011.1
Magnaporthe oryzae (rice blast fungus)	MGG_02727	XP_003721031.1
Neurospora crassa	NCU02167	XP_964526.2
Macaca mulatta (Rhesus monkey)	RAP1A	XP_001106027.1
Bos taurus (cattle)	RAP1A	NP_776873.1
Gallus gallus (chicken)	RAP1A	XP_417994.1
Xenopus tropicalis (tropical clawed frog)	rap1a	NP_001096357.1
Canis lupus familiaris (dog)	RAP1A	XP_863066.1
Danio rerio (zebrafish)	rap1aa	NP_001002152.1

Gene Ontology
Bibliography

Related articles in PubMed

Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion.
Rho SS, Kobayashi I, Oguri-Nakamura E, Ando K, Fujiwara M, Kamimura N, Hirata H, Iida A, Iwai Y, Mochizuki N, Fukuhara S
Developmental cell49(5)681-696.e6(2019 06)

Small molecule inhibition of RAS/MAPK signaling ameliorates developmental pathologies of Kabuki Syndrome.
Tsai IC, McKnight K, McKinstry SU, Maynard AT, Tan PL, Golzio C, White CT, Price DJ, Davis EE, Amrine-Madsen H, Katsanis N
Scientific reports8(1)10779(2018 Jul)

Evolution of complexity in the zebrafish synapse proteome.
Bayés À, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 03)

RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome.
Bögershausen N, Tsai IC, Pohl E, Kiper PÖ, Beleggia F, Percin EF, Keupp K, Matchan A, Milz E, Alanay Y, Kayserili H, Liu Y, Banka S, Kranz A, Zenker M, Wieczorek D, Elcioglu N, Prontera P, Lyonnet S, Meitinger T, Stewart AF, Donnai D, Strom TM, Boduroglu K, Yigit G, Li Y, Katsanis N, Wollnik B
The Journal of clinical investigation125(9)3585-99(2015 Sep)

Temporal pattern of loss/persistence of duplicate genes involved in signal transduction and metabolic pathways after teleost-specific genome duplication.
Sato Y, Hashiguchi Y, Nishida M
BMC evolutionary biology9127(2009 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following RAP1AB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAP1AB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa00488	NM_213405.2 Latest version!	Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ODa00488	NM_001243179.1 Latest version!	Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ODa00488	XM_005155801.2 Latest version!	Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ODa00488	XM_021479589.1 Latest version!	Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ODa00488	XM_021479590.1 Latest version!	Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RAP1AB ( NM_001243179.1 ) cDNA ORF clone, Danio rerio(Zebrafish) -> NP_001230108.1 Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ODa00488
Clone ID Related Accession (Same CDS sequence)	XM_021479589.1 , NM_001243179.1 , NM_213405.2 , XM_021479590.1 , XM_005155801.2
Accession Version	NM_001243179.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573747200000
Organism	Danio rerio(zebrafish)
Product	ras-related protein Rap-1b-like
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FP003590.14 and EH543099.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CK028186.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGTGAAT ACAAGCTTGT GGTGTTGGGC TCTGGTGGTG TGGGCAAGTC AGCCTTGACC 
GTCCAATTTG TTCAGGGGAT ATTCGTGGAG AAGTATGACC CTACAATTGA AGACTCCTAC 
AGAAAGCAAG TTGAAGTTGA TGGCCAGCAG TGCATGTTGG AAATCCTGGA CACAGCAGGA 
ACAGAGCAGT TCACAGCCAT GAGGGATCTG TACATGAAGA ACGGTCAGGG CTTTGCTCTC 
GTCTACTCAA TTACAGCTCA GTCTACATTC AATGACTTGC AGGACTTACG AGAGCAGATA 
CTACGTGTAA AGGATACAGA AGATGTGCCA ATGATCCTAG TTGGCAATAA GTGTGATCTG 
GAGGATGAAA GAGTTGTGGG GAAAGAACAG GGGCAAAATC TAGCCCGTCA GTGGAACAAC 
TGTGCCTTTT TAGAGTCTTC AGCCAAATCA AAAATCAATG TCCTTGATAT CTTCTATGAC 
TTGGTCAGAC AAATTAACAG GAAAACACCA GTGGAAAAGA AGAAAGCAAA AAAGAAGTCT 
AATTGTGTTC TCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001230108.1
CDS	304..861
Translation	MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVRQINRKTPVEKKKAKKKSNCVLL

Target ORF information:

RefSeq Version	NM_001243179.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001243179.1

ORF Insert Sequence:

ATGCGTGAAT ACAAGCTTGT GGTGTTGGGC TCTGGTGGTG TGGGCAAGTC AGCCTTGACC 
GTCCAATTTG TTCAGGGGAT ATTCGTGGAG AAGTATGACC CTACAATTGA AGACTCCTAC 
AGAAAGCAAG TTGAAGTTGA TGGCCAGCAG TGCATGTTGG AAATCCTGGA CACAGCAGGA 
ACAGAGCAGT TCACAGCCAT GAGGGATCTG TACATGAAGA ACGGTCAGGG CTTTGCTCTC 
GTCTACTCAA TTACAGCTCA GTCTACATTC AATGACTTGC AGGACTTACG AGAGCAGATA 
CTACGTGTAA AGGATACAGA AGATGTGCCA ATGATCCTAG TTGGCAATAA GTGTGATCTG 
GAGGATGAAA GAGTTGTGGG GAAAGAACAG GGGCAAAATC TAGCCCGTCA GTGGAACAAC 
TGTGCCTTTT TAGAGTCTTC AGCCAAATCA AAAATCAATG TCCTTGATAT CTTCTATGAC 
TTGGTCAGAC AAATTAACAG GAAAACACCA GTGGAAAAGA AGAAAGCAAA AAAGAAGTCT 
AATTGTGTTC TCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAP1AB ( NM_213405.2 ) cDNA ORF clone, Danio rerio(Zebrafish) -> NP_998570.2 Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ODa00488
Clone ID Related Accession (Same CDS sequence)	XM_021479589.1 , NM_001243179.1 , NM_213405.2 , XM_021479590.1 , XM_005155801.2
Accession Version	NM_213405.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573747200000
Organism	Danio rerio(zebrafish)
Product	ras-related protein Rap-1b-like
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FP003590.14. On Jul 30, 2011 this sequence version replaced NM_213405.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC049510.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGTGAAT ACAAGCTTGT GGTGTTGGGC TCTGGTGGTG TGGGCAAGTC AGCCTTGACC 
GTCCAATTTG TTCAGGGGAT ATTCGTGGAG AAGTATGACC CTACAATTGA AGACTCCTAC 
AGAAAGCAAG TTGAAGTTGA TGGCCAGCAG TGCATGTTGG AAATCCTGGA CACAGCAGGA 
ACAGAGCAGT TCACAGCCAT GAGGGATCTG TACATGAAGA ACGGTCAGGG CTTTGCTCTC 
GTCTACTCAA TTACAGCTCA GTCTACATTC AATGACTTGC AGGACTTACG AGAGCAGATA 
CTACGTGTAA AGGATACAGA AGATGTGCCA ATGATCCTAG TTGGCAATAA GTGTGATCTG 
GAGGATGAAA GAGTTGTGGG GAAAGAACAG GGGCAAAATC TAGCCCGTCA GTGGAACAAC 
TGTGCCTTTT TAGAGTCTTC AGCCAAATCA AAAATCAATG TCCTTGATAT CTTCTATGAC 
TTGGTCAGAC AAATTAACAG GAAAACACCA GTGGAAAAGA AGAAAGCAAA AAAGAAGTCT 
AATTGTGTTC TCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998570.2
CDS	402..959
Translation	MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVRQINRKTPVEKKKAKKKSNCVLL

Target ORF information:

RefSeq Version	NM_213405.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213405.2

ORF Insert Sequence:

ATGCGTGAAT ACAAGCTTGT GGTGTTGGGC TCTGGTGGTG TGGGCAAGTC AGCCTTGACC 
GTCCAATTTG TTCAGGGGAT ATTCGTGGAG AAGTATGACC CTACAATTGA AGACTCCTAC 
AGAAAGCAAG TTGAAGTTGA TGGCCAGCAG TGCATGTTGG AAATCCTGGA CACAGCAGGA 
ACAGAGCAGT TCACAGCCAT GAGGGATCTG TACATGAAGA ACGGTCAGGG CTTTGCTCTC 
GTCTACTCAA TTACAGCTCA GTCTACATTC AATGACTTGC AGGACTTACG AGAGCAGATA 
CTACGTGTAA AGGATACAGA AGATGTGCCA ATGATCCTAG TTGGCAATAA GTGTGATCTG 
GAGGATGAAA GAGTTGTGGG GAAAGAACAG GGGCAAAATC TAGCCCGTCA GTGGAACAAC 
TGTGCCTTTT TAGAGTCTTC AGCCAAATCA AAAATCAATG TCCTTGATAT CTTCTATGAC 
TTGGTCAGAC AAATTAACAG GAAAACACCA GTGGAAAAGA AGAAAGCAAA AAAGAAGTCT 
AATTGTGTTC TCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAP1AB ( XM_021479589.1 ) cDNA ORF clone, Danio rerio(Zebrafish) -> XP_021335264.1 Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa00488
Clone ID Related Accession (Same CDS sequence)	XM_021479589.1 , NM_001243179.1 , NM_213405.2 , XM_021479590.1 , XM_005155801.2
Accession Version	XM_021479589.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1497369600000
Organism	Danio rerio(zebrafish)
Product	ras-related protein Rap-1b-like isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007122.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGTGAAT ACAAGCTTGT GGTGTTGGGC TCTGGTGGTG TGGGCAAGTC AGCCTTGACC 
GTCCAATTTG TTCAGGGGAT ATTCGTGGAG AAGTATGACC CTACAATTGA AGACTCCTAC 
AGAAAGCAAG TTGAAGTTGA TGGCCAGCAG TGCATGTTGG AAATCCTGGA CACAGCAGGA 
ACAGAGCAGT TCACAGCCAT GAGGGATCTG TACATGAAGA ACGGTCAGGG CTTTGCTCTC 
GTCTACTCAA TTACAGCTCA GTCTACATTC AATGACTTGC AGGACTTACG AGAGCAGATA 
CTACGTGTAA AGGATACAGA AGATGTGCCA ATGATCCTAG TTGGCAATAA GTGTGATCTG 
GAGGATGAAA GAGTTGTGGG GAAAGAACAG GGGCAAAATC TAGCCCGTCA GTGGAACAAC 
TGTGCCTTTT TAGAGTCTTC AGCCAAATCA AAAATCAATG TCCTTGATAT CTTCTATGAC 
TTGGTCAGAC AAATTAACAG GAAAACACCA GTGGAAAAGA AGAAAGCAAA AAAGAAGTCT 
AATTGTGTTC TCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_021335264.1
CDS	1843..2400
Translation	MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVRQINRKTPVEKKKAKKKSNCVLL

Target ORF information:

RefSeq Version	XM_021479589.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_021479589.1

ORF Insert Sequence:

ATGCGTGAAT ACAAGCTTGT GGTGTTGGGC TCTGGTGGTG TGGGCAAGTC AGCCTTGACC 
GTCCAATTTG TTCAGGGGAT ATTCGTGGAG AAGTATGACC CTACAATTGA AGACTCCTAC 
AGAAAGCAAG TTGAAGTTGA TGGCCAGCAG TGCATGTTGG AAATCCTGGA CACAGCAGGA 
ACAGAGCAGT TCACAGCCAT GAGGGATCTG TACATGAAGA ACGGTCAGGG CTTTGCTCTC 
GTCTACTCAA TTACAGCTCA GTCTACATTC AATGACTTGC AGGACTTACG AGAGCAGATA 
CTACGTGTAA AGGATACAGA AGATGTGCCA ATGATCCTAG TTGGCAATAA GTGTGATCTG 
GAGGATGAAA GAGTTGTGGG GAAAGAACAG GGGCAAAATC TAGCCCGTCA GTGGAACAAC 
TGTGCCTTTT TAGAGTCTTC AGCCAAATCA AAAATCAATG TCCTTGATAT CTTCTATGAC 
TTGGTCAGAC AAATTAACAG GAAAACACCA GTGGAAAAGA AGAAAGCAAA AAAGAAGTCT 
AATTGTGTTC TCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAP1AB ( XM_021479590.1 ) cDNA ORF clone, Danio rerio(Zebrafish) -> XP_021335265.1 Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ODa00488
Clone ID Related Accession (Same CDS sequence)	XM_021479589.1 , NM_001243179.1 , NM_213405.2 , XM_021479590.1 , XM_005155801.2
Accession Version	XM_021479590.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1497369600000
Organism	Danio rerio(zebrafish)
Product	ras-related protein Rap-1b-like isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007122.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGTGAAT ACAAGCTTGT GGTGTTGGGC TCTGGTGGTG TGGGCAAGTC AGCCTTGACC 
GTCCAATTTG TTCAGGGGAT ATTCGTGGAG AAGTATGACC CTACAATTGA AGACTCCTAC 
AGAAAGCAAG TTGAAGTTGA TGGCCAGCAG TGCATGTTGG AAATCCTGGA CACAGCAGGA 
ACAGAGCAGT TCACAGCCAT GAGGGATCTG TACATGAAGA ACGGTCAGGG CTTTGCTCTC 
GTCTACTCAA TTACAGCTCA GTCTACATTC AATGACTTGC AGGACTTACG AGAGCAGATA 
CTACGTGTAA AGGATACAGA AGATGTGCCA ATGATCCTAG TTGGCAATAA GTGTGATCTG 
GAGGATGAAA GAGTTGTGGG GAAAGAACAG GGGCAAAATC TAGCCCGTCA GTGGAACAAC 
TGTGCCTTTT TAGAGTCTTC AGCCAAATCA AAAATCAATG TCCTTGATAT CTTCTATGAC 
TTGGTCAGAC AAATTAACAG GAAAACACCA GTGGAAAAGA AGAAAGCAAA AAAGAAGTCT 
AATTGTGTTC TCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_021335265.1
CDS	311..868
Translation	MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVRQINRKTPVEKKKAKKKSNCVLL

Target ORF information:

RefSeq Version	XM_021479590.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_021479590.1

ORF Insert Sequence:

ATGCGTGAAT ACAAGCTTGT GGTGTTGGGC TCTGGTGGTG TGGGCAAGTC AGCCTTGACC 
GTCCAATTTG TTCAGGGGAT ATTCGTGGAG AAGTATGACC CTACAATTGA AGACTCCTAC 
AGAAAGCAAG TTGAAGTTGA TGGCCAGCAG TGCATGTTGG AAATCCTGGA CACAGCAGGA 
ACAGAGCAGT TCACAGCCAT GAGGGATCTG TACATGAAGA ACGGTCAGGG CTTTGCTCTC 
GTCTACTCAA TTACAGCTCA GTCTACATTC AATGACTTGC AGGACTTACG AGAGCAGATA 
CTACGTGTAA AGGATACAGA AGATGTGCCA ATGATCCTAG TTGGCAATAA GTGTGATCTG 
GAGGATGAAA GAGTTGTGGG GAAAGAACAG GGGCAAAATC TAGCCCGTCA GTGGAACAAC 
TGTGCCTTTT TAGAGTCTTC AGCCAAATCA AAAATCAATG TCCTTGATAT CTTCTATGAC 
TTGGTCAGAC AAATTAACAG GAAAACACCA GTGGAAAAGA AGAAAGCAAA AAAGAAGTCT 
AATTGTGTTC TCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAP1AB ( XM_005155801.2 ) cDNA ORF clone, Danio rerio(Zebrafish) -> XP_005155858.1 Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa00488
Clone ID Related Accession (Same CDS sequence)	XM_021479589.1 , NM_001243179.1 , NM_213405.2 , XM_021479590.1 , XM_005155801.2
Accession Version	XM_005155801.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466611200000
Organism	Danio rerio(Zebrafish)
Product	ras-related protein Rap-1b-like isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007122.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_005155801.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGTGAAT ACAAGCTTGT GGTGTTGGGC TCTGGTGGTG TGGGCAAGTC AGCCTTGACC 
GTCCAATTTG TTCAGGGGAT ATTCGTGGAG AAGTATGACC CTACAATTGA AGACTCCTAC 
AGAAAGCAAG TTGAAGTTGA TGGCCAGCAG TGCATGTTGG AAATCCTGGA CACAGCAGGA 
ACAGAGCAGT TCACAGCCAT GAGGGATCTG TACATGAAGA ACGGTCAGGG CTTTGCTCTC 
GTCTACTCAA TTACAGCTCA GTCTACATTC AATGACTTGC AGGACTTACG AGAGCAGATA 
CTACGTGTAA AGGATACAGA AGATGTGCCA ATGATCCTAG TTGGCAATAA GTGTGATCTG 
GAGGATGAAA GAGTTGTGGG GAAAGAACAG GGGCAAAATC TAGCCCGTCA GTGGAACAAC 
TGTGCCTTTT TAGAGTCTTC AGCCAAATCA AAAATCAATG TCCTTGATAT CTTCTATGAC 
TTGGTCAGAC AAATTAACAG GAAAACACCA GTGGAAAAGA AGAAAGCAAA AAAGAAGTCT 
AATTGTGTTC TCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005155858.1
CDS	301..858
Translation	MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVRQINRKTPVEKKKAKKKSNCVLL

Target ORF information:

RefSeq Version	XM_005155801.2
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio RAP1A, member of RAS oncogene family b (rap1ab), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005155801.2

ORF Insert Sequence:

ATGCGTGAAT ACAAGCTTGT GGTGTTGGGC TCTGGTGGTG TGGGCAAGTC AGCCTTGACC 
GTCCAATTTG TTCAGGGGAT ATTCGTGGAG AAGTATGACC CTACAATTGA AGACTCCTAC 
AGAAAGCAAG TTGAAGTTGA TGGCCAGCAG TGCATGTTGG AAATCCTGGA CACAGCAGGA 
ACAGAGCAGT TCACAGCCAT GAGGGATCTG TACATGAAGA ACGGTCAGGG CTTTGCTCTC 
GTCTACTCAA TTACAGCTCA GTCTACATTC AATGACTTGC AGGACTTACG AGAGCAGATA 
CTACGTGTAA AGGATACAGA AGATGTGCCA ATGATCCTAG TTGGCAATAA GTGTGATCTG 
GAGGATGAAA GAGTTGTGGG GAAAGAACAG GGGCAAAATC TAGCCCGTCA GTGGAACAAC 
TGTGCCTTTT TAGAGTCTTC AGCCAAATCA AAAATCAATG TCCTTGATAT CTTCTATGAC 
TTGGTCAGAC AAATTAACAG GAAAACACCA GTGGAAAAGA AGAAAGCAAA AAAGAAGTCT 
AATTGTGTTC TCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion.
Developmental cell49(5)681-696.e6(2019 06)
Rho SS,Kobayashi I,Oguri-Nakamura E,Ando K,Fujiwara M,Kamimura N,Hirata H,Iida A,Iwai Y,Mochizuki N,Fukuhara S

Small molecule inhibition of RAS/MAPK signaling ameliorates developmental pathologies of Kabuki Syndrome.
Scientific reports8(1)10779(2018 Jul)
Tsai IC,McKnight K,McKinstry SU,Maynard AT,Tan PL,Golzio C,White CT,Price DJ,Davis EE,Amrine-Madsen H,Katsanis N

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 03)
Bayés À,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome.
The Journal of clinical investigation125(9)3585-99(2015 Sep)
Bögershausen N,Tsai IC,Pohl E,Kiper PÖ,Beleggia F,Percin EF,Keupp K,Matchan A,Milz E,Alanay Y,Kayserili H,Liu Y,Banka S,Kranz A,Zenker M,Wieczorek D,Elcioglu N,Prontera P,Lyonnet S,Meitinger T,Stewart AF,Donnai D,Strom TM,Boduroglu K,Yigit G,Li Y,Katsanis N,Wollnik B

Temporal pattern of loss/persistence of duplicate genes involved in signal transduction and metabolic pathways after teleost-specific genome duplication.
BMC evolutionary biology9127(2009 Jun)
Sato Y,Hashiguchi Y,Nishida M

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RAP1AB cDNA ORF clone, Danio rerio(Zebrafish)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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