rrm2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	rrm2
Entrez Gene ID	30733
Full Name	ribonucleotide reductase M2 polypeptide
Synonyms	cb111,chunp6884,r2
General protein information	Preferred Names ribonucleotide reductase M2 polypeptide Names ribonucleoside-diphosphate reductase subunit M2 etID309896.20 reductase M2 polypeptide variant 1 reductase M2 polypeptide variant 2 reductase M2 polypeptide variant 3a reductase M2 polypeptide variant 3b reductase M2 polypeptide variant 3c reductase M2 polypeptide variant 3d ribonucleotide reductase protein r2 class I ribonucleotide reductase small chain ribonucleotide reductase small subunit
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_131450.2	NP_571525.1	ribonucleoside-diphosphate reductase subunit M2
NM_131450.3	NP_571525.1	ribonucleoside-diphosphate reductase subunit M2

Pathways from BioSystems

Homologies

Eremothecium gossypii	AGOS_AAL136C	NP_982406.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006818	XP_308927.4
Macaca mulatta (Rhesus monkey)	RRM2	XP_001091447.2
Canis lupus familiaris (dog)	RRM2	XP_540076.2
Gallus gallus (chicken)	RRM2	XP_004935811.1
Schizosaccharomyces pombe (fission yeast)	suc22	NP_596546.1
Danio rerio (zebrafish)	rrm2	NP_571525.1
Drosophila melanogaster (fruit fly)	RnrS	NP_525111.1
Xenopus tropicalis (tropical clawed frog)	rrm2.2	NP_001007890.1
Danio rerio (zebrafish)	LOC100330864	XP_002665783.1
Kluyveromyces lactis	KLLA0F15103g	XP_455757.1
Neurospora crassa	NCU07887	XP_962820.1
Homo sapiens (human)	RRM2	NP_001159403.1
Pan troglodytes (chimpanzee)	RRM2	XP_003949799.1
Arabidopsis thaliana (thale cress)	TSO2	NP_189342.1
Oryza sativa (rice)	Os06g0127900	NP_001056668.1
Magnaporthe oryzae (rice blast fungus)	MGG_06408	XP_003717161.1
Bos taurus (cattle)	RRM2	NP_001231110.1
Mus musculus (house mouse)	Rrm2	NP_033130.1
Rattus norvegicus (Norway rat)	Rrm2	NP_001020911.1
Caenorhabditis elegans (roundworm)	rnr-2	NP_497821.1
Saccharomyces cerevisiae (baker's yeast)	RNR2	NP_012508.1
Rattus norvegicus (Norway rat)	LOC100359539	XP_006255398.1

Gene Ontology
Bibliography

Related articles in PubMed

Modulation of TNFα Activity by the microRNA Let-7 Coordinates Zebrafish Heart Regeneration.
Smith AM, Dykeman CA, King BL, Yin VP
iScience151-15(2019 May)

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo.
Wagner DE, Weinreb C, Collins ZM, Briggs JA, Megason SG, Klein AM
Science (New York, N.Y.)360(6392)981-987(2018 06)

Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum.
Takeuchi M, Yamaguchi S, Sakakibara Y, Hayashi T, Matsuda K, Hara Y, Tanegashima C, Shimizu T, Kuraku S, Hibi M
The Journal of comparative neurology525(7)1558-1585(2017 May)

Molecular insights of organochlorine biocide-induced toxicity in zebrafish: Whole-adult-organism toxicogenomics, targeted gene expression and histological analyses.
Lui EY, Li C, Li ZH, Gong Z, Lam SH
Journal of genetics and genomics = Yi chuan xue bao43(8)525-8(2016 08)

Overexpression of Jak1 Activating Mutants in Hepatocytes Is Insufficient to Generate Hepatocellular Carcinoma in Zebrafish.
Yuan Y, Zhang J, Zhou Q
Journal of genetics and genomics = Yi chuan xue bao43(2)99-102(2016 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following rrm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the rrm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa00597	NM_131450.3 Latest version!	Danio rerio ribonucleotide reductase M2 polypeptide (rrm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
ODa00597	NM_131450.2	Danio rerio ribonucleotide reductase M2 polypeptide (rrm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

rrm2 ( NM_131450.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_571525.1 Danio rerio ribonucleotide reductase M2 polypeptide (rrm2), mRNA.

Price & Availability↑

CloneID	ODa00597
Clone ID Related Accession (Same CDS sequence)	NM_131450.2 , NM_131450.3
Accession Version	NM_131450.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1161bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466784000000
Organism	Danio rerio(Zebrafish)
Product	ribonucleoside-diphosphate reductase subunit M2
Comment	PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC044355.1. On Dec 20, 2003 this sequence version replaced NM_131450.1. ##Evidence-Data-START## Transcript exon combination :: BC044355.1, BC075746.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGTCGTCCA CTCGCTCTCC CCTGAAAACC AAGAATGAAA ACACAATCTC TACTAAAATG 
AATAACATGT CCTTTGTGGA CAAAGAAAAC ACGCCACCCA GTTTGAGCTC CACCAGAATC 
CTGGCGTCCA AAACGGCGCG CAAAATCTTT GATGAATCAG AGGGGCAGTC GAAAGCAAAG 
AAAGGAGCAG TGGAGGAGGA GCCTCTTCTG AAGGAGAACC CCCATCGCTT TGTCATTTTC 
CCAATTCAGT ATCATGACAT CTGGCAGATG TACAAGAAGG CAGAGGCCTC TTTCTGGACA 
GCTGAGGAGG TTGATCTGTC CAAAGATCTG CAACACTGGG ATTCCCTGAA AGACGAGGAG 
AGATATTTCA TCTCCCATGT TCTGGCTTTC TTTGCTGCAA GTGATGGCAT TGTCAATGAG 
AACTTGGTGG AGCGTTTCAC TCAGGAGGTC CAGGTGACTG AAGCCCGCTG CTTCTATGGC 
TTCCAGATAG CAATGGAAAA CATCCACTCA GAAATGTACA GCCTGTTGAT TGACACCTAC 
ATTAAAGATT CTAAAGAGAG GGAATTTTTG TTCAATGCCA TTGAGACAAT GCCATGTGTA 
AAGAAGAAGG CTGACTGGGC ACTCAACTGG ATTGGTGATA AAAATGCACG ATATGGTGAG 
AGAGTGGTGG CCTTTGCTGC AGTGGAGGGA ATCTTCTTCT CTGGGTCTTT TGCTTCTATT 
TTCTGGCTAA AGAAGAGGGG ACTCATGCCT GGACTCACCT TCTCCAATGA GCTGATCAGC 
AGAGATGAGG GTCTTCATTG CGACTTCGCC TGCCTCATGT TTAAACACTT GATCAACAAA 
CCATCAGAAG AAACCGTGAA GAAAATCATC ATGAATGCAG TTGAAATTGA GCAGGAGTTC 
CTGACTGATG CTCTTCCCGT GAAGCTCATT GGCATGAACT GTGACCTGAT GAAGCAGTAC 
ATTGAGTTTG TGGCTGACCG ACTGTTGCTG GAGCTGGGAT TTGACAAGGT CTATAGAGTG 
GAGAATCCTT TTGACTTCAT GGAGAACATT TCGTTGGAGG GCAAGACCAA CTTCTTCGAG 
AAGCGAGTGG GCGAGTACCA GCGCATGGGA GTCATGTCGG GAACTACAGA TAACACTTTC 
ACTCTGGATG CTGATTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_571525.1
CDS	150..1310
Translation	MSSTRSPLKTKNENTISTKMNNMSFVDKENTPPSLSSTRILASKTARKIFDESEGQSKAKKGAVEEEPLLKENPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWDSLKDEERYFISHVLAFFAASDGIVNENLVERFTQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREFLFNAIETMPCVKKKADWALNWIGDKNARYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLINKPSEETVKKIIMNAVEIEQEFLTDALPVKLIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSGTTDNTFTLDADF

Target ORF information:

RefSeq Version	NM_131450.2
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio ribonucleotide reductase M2 polypeptide (rrm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131450.2

ORF Insert Sequence:

ATGTCGTCCA CTCGCTCTCC CCTGAAAACC AAGAATGAAA ACACAATCTC TACTAAAATG 
AATAACATGT CCTTTGTGGA CAAAGAAAAC ACGCCACCCA GTTTGAGCTC CACCAGAATC 
CTGGCGTCCA AAACGGCGCG CAAAATCTTT GATGAATCAG AGGGGCAGTC GAAAGCAAAG 
AAAGGAGCAG TGGAGGAGGA GCCTCTTCTG AAGGAGAACC CCCATCGCTT TGTCATTTTC 
CCAATTCAGT ATCATGACAT CTGGCAGATG TACAAGAAGG CAGAGGCCTC TTTCTGGACA 
GCTGAGGAGG TTGATCTGTC CAAAGATCTG CAACACTGGG ATTCCCTGAA AGACGAGGAG 
AGATATTTCA TCTCCCATGT TCTGGCTTTC TTTGCTGCAA GTGATGGCAT TGTCAATGAG 
AACTTGGTGG AGCGTTTCAC TCAGGAGGTC CAGGTGACTG AAGCCCGCTG CTTCTATGGC 
TTCCAGATAG CAATGGAAAA CATCCACTCA GAAATGTACA GCCTGTTGAT TGACACCTAC 
ATTAAAGATT CTAAAGAGAG GGAATTTTTG TTCAATGCCA TTGAGACAAT GCCATGTGTA 
AAGAAGAAGG CTGACTGGGC ACTCAACTGG ATTGGTGATA AAAATGCACG ATATGGTGAG 
AGAGTGGTGG CCTTTGCTGC AGTGGAGGGA ATCTTCTTCT CTGGGTCTTT TGCTTCTATT 
TTCTGGCTAA AGAAGAGGGG ACTCATGCCT GGACTCACCT TCTCCAATGA GCTGATCAGC 
AGAGATGAGG GTCTTCATTG CGACTTCGCC TGCCTCATGT TTAAACACTT GATCAACAAA 
CCATCAGAAG AAACCGTGAA GAAAATCATC ATGAATGCAG TTGAAATTGA GCAGGAGTTC 
CTGACTGATG CTCTTCCCGT GAAGCTCATT GGCATGAACT GTGACCTGAT GAAGCAGTAC 
ATTGAGTTTG TGGCTGACCG ACTGTTGCTG GAGCTGGGAT TTGACAAGGT CTATAGAGTG 
GAGAATCCTT TTGACTTCAT GGAGAACATT TCGTTGGAGG GCAAGACCAA CTTCTTCGAG 
AAGCGAGTGG GCGAGTACCA GCGCATGGGA GTCATGTCGG GAACTACAGA TAACACTTTC 
ACTCTGGATG CTGATTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

rrm2 ( NM_131450.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_571525.1 Danio rerio ribonucleotide reductase M2 polypeptide (rrm2), mRNA.

Price & Availability↑

CloneID	ODa00597
Clone ID Related Accession (Same CDS sequence)	NM_131450.2 , NM_131450.3
Accession Version	NM_131450.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1161bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577462400000
Organism	Danio rerio(zebrafish)
Product	ribonucleoside-diphosphate reductase subunit M2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU695215.3. On May 23, 2017 this sequence version replaced NM_131450.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC044355.1, GDQQ01000887.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGTCCA CTCGCTCTCC CCTGAAAACC AAGAATGAAA ACACAATCTC TACTAAAATG 
AATAACATGT CCTTTGTGGA CAAAGAAAAC ACGCCACCCA GTTTGAGCTC CACCAGAATC 
CTGGCGTCCA AAACGGCGCG CAAAATCTTT GATGAATCAG AGGGGCAGTC GAAAGCAAAG 
AAAGGAGCAG TGGAGGAGGA GCCTCTTCTG AAGGAGAACC CCCATCGCTT TGTCATTTTC 
CCAATTCAGT ATCATGACAT CTGGCAGATG TACAAGAAGG CAGAGGCCTC TTTCTGGACA 
GCTGAGGAGG TTGATCTGTC CAAAGATCTG CAACACTGGG ATTCCCTGAA AGACGAGGAG 
AGATATTTCA TCTCCCATGT TCTGGCTTTC TTTGCTGCAA GTGATGGCAT TGTCAATGAG 
AACTTGGTGG AGCGTTTCAC TCAGGAGGTC CAGGTGACTG AAGCCCGCTG CTTCTATGGC 
TTCCAGATAG CAATGGAAAA CATCCACTCA GAAATGTACA GCCTGTTGAT TGACACCTAC 
ATTAAAGATT CTAAAGAGAG GGAATTTTTG TTCAATGCCA TTGAGACAAT GCCATGTGTA 
AAGAAGAAGG CTGACTGGGC ACTCAACTGG ATTGGTGATA AAAATGCACG ATATGGTGAG 
AGAGTGGTGG CCTTTGCTGC AGTGGAGGGA ATCTTCTTCT CTGGGTCTTT TGCTTCTATT 
TTCTGGCTAA AGAAGAGGGG ACTCATGCCT GGACTCACCT TCTCCAATGA GCTGATCAGC 
AGAGATGAGG GTCTTCATTG CGACTTCGCC TGCCTCATGT TTAAACACTT GATCAACAAA 
CCATCAGAAG AAACCGTGAA GAAAATCATC ATGAATGCAG TTGAAATTGA GCAGGAGTTC 
CTGACTGATG CTCTTCCCGT GAAGCTCATT GGCATGAACT GTGACCTGAT GAAGCAGTAC 
ATTGAGTTTG TGGCTGACCG ACTGTTGCTG GAGCTGGGAT TTGACAAGGT CTATAGAGTG 
GAGAATCCTT TTGACTTCAT GGAGAACATT TCGTTGGAGG GCAAGACCAA CTTCTTCGAG 
AAGCGAGTGG GCGAGTACCA GCGCATGGGA GTCATGTCGG GAACTACAGA TAACACTTTC 
ACTCTGGATG CTGATTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_571525.1
CDS	181..1341
Translation	MSSTRSPLKTKNENTISTKMNNMSFVDKENTPPSLSSTRILASKTARKIFDESEGQSKAKKGAVEEEPLLKENPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWDSLKDEERYFISHVLAFFAASDGIVNENLVERFTQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREFLFNAIETMPCVKKKADWALNWIGDKNARYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLINKPSEETVKKIIMNAVEIEQEFLTDALPVKLIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSGTTDNTFTLDADF

Target ORF information:

RefSeq Version	NM_131450.3
Organism	Danio rerio(zebrafish)
Definition	Danio rerio ribonucleotide reductase M2 polypeptide (rrm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131450.3

ORF Insert Sequence:

ATGTCGTCCA CTCGCTCTCC CCTGAAAACC AAGAATGAAA ACACAATCTC TACTAAAATG 
AATAACATGT CCTTTGTGGA CAAAGAAAAC ACGCCACCCA GTTTGAGCTC CACCAGAATC 
CTGGCGTCCA AAACGGCGCG CAAAATCTTT GATGAATCAG AGGGGCAGTC GAAAGCAAAG 
AAAGGAGCAG TGGAGGAGGA GCCTCTTCTG AAGGAGAACC CCCATCGCTT TGTCATTTTC 
CCAATTCAGT ATCATGACAT CTGGCAGATG TACAAGAAGG CAGAGGCCTC TTTCTGGACA 
GCTGAGGAGG TTGATCTGTC CAAAGATCTG CAACACTGGG ATTCCCTGAA AGACGAGGAG 
AGATATTTCA TCTCCCATGT TCTGGCTTTC TTTGCTGCAA GTGATGGCAT TGTCAATGAG 
AACTTGGTGG AGCGTTTCAC TCAGGAGGTC CAGGTGACTG AAGCCCGCTG CTTCTATGGC 
TTCCAGATAG CAATGGAAAA CATCCACTCA GAAATGTACA GCCTGTTGAT TGACACCTAC 
ATTAAAGATT CTAAAGAGAG GGAATTTTTG TTCAATGCCA TTGAGACAAT GCCATGTGTA 
AAGAAGAAGG CTGACTGGGC ACTCAACTGG ATTGGTGATA AAAATGCACG ATATGGTGAG 
AGAGTGGTGG CCTTTGCTGC AGTGGAGGGA ATCTTCTTCT CTGGGTCTTT TGCTTCTATT 
TTCTGGCTAA AGAAGAGGGG ACTCATGCCT GGACTCACCT TCTCCAATGA GCTGATCAGC 
AGAGATGAGG GTCTTCATTG CGACTTCGCC TGCCTCATGT TTAAACACTT GATCAACAAA 
CCATCAGAAG AAACCGTGAA GAAAATCATC ATGAATGCAG TTGAAATTGA GCAGGAGTTC 
CTGACTGATG CTCTTCCCGT GAAGCTCATT GGCATGAACT GTGACCTGAT GAAGCAGTAC 
ATTGAGTTTG TGGCTGACCG ACTGTTGCTG GAGCTGGGAT TTGACAAGGT CTATAGAGTG 
GAGAATCCTT TTGACTTCAT GGAGAACATT TCGTTGGAGG GCAAGACCAA CTTCTTCGAG 
AAGCGAGTGG GCGAGTACCA GCGCATGGGA GTCATGTCGG GAACTACAGA TAACACTTTC 
ACTCTGGATG CTGATTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Modulation of TNFα Activity by the microRNA Let-7 Coordinates Zebrafish Heart Regeneration.
iScience151-15(2019 May)
Smith AM,Dykeman CA,King BL,Yin VP

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo.
Science (New York, N.Y.)360(6392)981-987(2018 06)
Wagner DE,Weinreb C,Collins ZM,Briggs JA,Megason SG,Klein AM

Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum.
The Journal of comparative neurology525(7)1558-1585(2017 May)
Takeuchi M,Yamaguchi S,Sakakibara Y,Hayashi T,Matsuda K,Hara Y,Tanegashima C,Shimizu T,Kuraku S,Hibi M

Molecular insights of organochlorine biocide-induced toxicity in zebrafish: Whole-adult-organism toxicogenomics, targeted gene expression and histological analyses.
Journal of genetics and genomics = Yi chuan xue bao43(8)525-8(2016 08)
Lui EY,Li C,Li ZH,Gong Z,Lam SH

Overexpression of Jak1 Activating Mutants in Hepatocytes Is Insufficient to Generate Hepatocellular Carcinoma in Zebrafish.
Journal of genetics and genomics = Yi chuan xue bao43(2)99-102(2016 Feb)
Yuan Y,Zhang J,Zhou Q

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rrm2 cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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