ATP2A2 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	ATP2A2
Entrez Gene ID	403878
Full Name	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
Synonyms	SERCA2A
General protein information	Preferred Names ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Names sarcoplasmic/endoplasmic reticulum calcium ATPase 2 SERCA2 SR Ca(2+)-ATPase 2 calcium ATPase calcium pump 2 calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform endoplasmic reticulum class 1/2 Ca(2+) ATPase sarcoplasmic reticulum Ca2+-transport ATPase isoform
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003214.1	NP_001003214.1	sarcoplasmic/endoplasmic reticulum calcium ATPase 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ATP2A2	NP_001178359.1
Rattus norvegicus (Norway rat)	Atp2a2	NP_001104293.1
Mus musculus (house mouse)	Atp2a2	NP_001103610.1
Pan troglodytes (chimpanzee)	ATP2A2	XP_001141455.1
Gallus gallus (chicken)	ATP2A2	NP_001258903.1
Xenopus tropicalis (tropical clawed frog)	atp2a2	XP_004910568.1
Homo sapiens (human)	ATP2A2	NP_733765.1
Canis lupus familiaris (dog)	ATP2A2	NP_001003214.1
Danio rerio (zebrafish)	atp2a2a	NP_957259.1

Gene Ontology
Bibliography

Related articles in PubMed

Cardiac Calcium ATPase Dimerization Measured by Cross-Linking and Fluorescence Energy Transfer.
Blackwell DJ, Zak TJ, Robia SL
Biophysical journal111(6)1192-1202(2016 Sep)

2-Color calcium pump reveals closure of the cytoplasmic headpiece with calcium binding.
Hou Z, Hu Z, Blackwell DJ, Miller TD, Thomas DD, Robia SL
PloS one7(7)e40369(2012)

Superinhibitory phospholamban mutants compete with Ca2+ for binding to SERCA2a by stabilizing a unique nucleotide-dependent conformational state.
Akin BL, Chen Z, Jones LR
The Journal of biological chemistry285(37)28540-52(2010 Sep)

Ca2+ binding to site I of the cardiac Ca2+ pump is sufficient to dissociate phospholamban.
Chen Z, Akin BL, Jones LR
The Journal of biological chemistry285(5)3253-60(2010 Jan)

Mechanism of reversal of phospholamban inhibition of the cardiac Ca2+-ATPase by protein kinase A and by anti-phospholamban monoclonal antibody 2D12.
Chen Z, Akin BL, Jones LR
The Journal of biological chemistry282(29)20968-76(2007 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ATP2A2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATP2A2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe00052	NM_001003214.1 Latest version!	Canis lupus familiaris ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 (ATP2A2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ATP2A2 ( NM_001003214.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001003214.1 Canis lupus familiaris ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 (ATP2A2), mRNA.

Price & Availability↑

CloneID	OCe00052
Clone ID Related Accession (Same CDS sequence)	NM_001003214.1
Accession Version	NM_001003214.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2994bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571328000000
Organism	Canis lupus familiaris(dog)
Product	sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U94345.1. ##Evidence-Data-START## Transcript exon combination :: U94345.1, EU136187.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAACG CGCACACAAA GACGGTGGAG GAGGTGCTGG GCCACTTCGG CGTCAACGAG 
AGCACGGGGC TGAGTCTGGA GCAGGTCAAG AAGCTCAAGG AGAGATGGGG CTCCAACGAG 
TTACCGGCCG AAGAAGGAAA AACCTTGCTG GAACTTGTGA TCGAGCAGTT TGAAGACTTA 
CTAGTTCGAA TATTATTGCT GGCAGCGTGT ATATCTTTTG TTTTGGCTTG GTTTGAAGAA 
GGTGAAGAAA CAATTACAGC CTTTGTAGAA CCCTTTGTAA TTTTACTTAT ATTAGTAGCC 
AATGCAATTG TGGGTGTATG GCAGGAGAGA AATGCTGAGA ATGCGATCGA AGCACTTAAG 
GAATATGAGC CTGAAATGGG CAAAGTATAT CGACAGGACA GAAAGAGTGT CCAGCGGATT 
AAAGCTAAAG ACATAGTTCC TGGTGATATT GTAGAAATTG CTGTTGGTGA CAAAGTTCCT 
GCTGATATAA GATTAACATC CATCAAATCT ACGACTCTAA GAGTTGACCA GTCCATTCTC 
ACAGGTGAGT CTGTGTCTGT CATCAAGCAC ACTGACCCGG TCCCAGACCC ACGGGCTGTC 
AATCAAGATA AAAAGAATAT GCTCTTTTCT GGTACAAACA TTGCTGCTGG CAAAGCCATG 
GGAGTGGTAG TGGCAACTGG AGTGAACACA GAAATTGGCA AGATCCGGGA TGAAATGGTA 
GCAACAGAGC AGGAGAGAAC CCCACTCCAG CAGAAACTAG ATGAGTTTGG GGAACAGCTT 
TCCAAAGTCA TCTCCCTGAT TTGCATCGCA GTCTGGATCA TAAACATTGG GCACTTCAAT 
GACCCAGTTC ATGGAGGCTC CTGGATCAGA GGTGCTATTT ACTACTTCAA AATTGCAGTG 
GCCCTGGCTG TGGCAGCCAT TCCTGAAGGT CTGCCTGCTG TCATCACCAC CTGCCTGGCT 
CTTGGAACTC GCAGAATGGC TAAGAAAAAT GCCATTGTTC GAAGCCTCCC TTCTGTGGAA 
ACCCTAGGTT GTACTTCTGT TATCTGCTCA GACAAGACTG GTACACTGAC AACGAACCAG 
ATGTCTGTGT GCAGGATGTT CATTCTGGAC AGAGTTGAAG GTGATAGCTG CTCCCTTAAT 
GAGTTTACCA TTACTGGATC AACATACGCA CCTATTGGAG AAGTGCATAA AGATGATAAA 
CCAGTGAAAT GTCATCAATA TGATGGTCTT GTGGAATTGG CAACCATCTG TGCTCTTTGT 
AATGATTCTG CATTGGATTA CAATGAGGCG AAGGGTGTGT ATGAAAAAGT TGGAGAAGCT 
ACAGAGACTG CTCTCACATG CCTAGTAGAG AAGATGAATG TATTTGATAC CGAATTGAAG 
GGTCTTTCTA AAATAGAGCG AGCAAATGCC TGCAACTCGG TCATTAAGCA GTTGATGAAA 
AAGGAATTTA CTTTGGAGTT TTCACGTGAT AGAAAATCAA TGTCAGTTTA TTGTACACCA 
AACAAACCGA GCCGGACTTC GATGAGCAAA ATGTTTGTGA AGGGGGCTCC TGAAGGTGTC 
ATTGACAGGT GCACCCACAT TCGAGTTGGA AGTACTAAAG TCCCTATGAC CCCAGGCGTC 
AAACAGAAGG TCATGTCTGT CATTCGGGAA TGGGGTAGCG GCAGCGACAC ACTGCGGTGC 
CTGGCCCTGG CCACCCACGA CAACCCTCTG AGAAGAGAAG AAATGAACCT TGAGGACTCT 
GCCAACTTTA TTAAATATGA GACCAATCTG ACTTTCGTTG GATGCGTGGG CATGCTGGAT 
CCTCCAAGGA TTGAAGTGGC CTCCTCTGTA AAGCTGTGCC GGCAAGCAGG CATCCGAGTC 
ATTATGATCA CAGGAGACAA CAAGGGCACG GCAGTGGCCA TCTGTCGGCG CATTGGCATC 
TTTGGACAGG ACGAAGATGT GACGTCAAAG GCTTTTACAG GCCGGGAGTT TGATGAGCTC 
AGTCCTTCAG CCCAGAGGGA TGCCTGCTTG AATGCCCGCT GTTTTGCTCG AGTCGAACCT 
TCCCACAAGT CAAAAATTGT AGAATTCCTT CAGTCTTTTG ATGAGATTAC AGCCATGACT 
GGGGATGGTG TGAATGATGC TCCTGCCCTG AAGAAATCGG AGATCGGCAT TGCCATGGGC 
TCGGGCACAG CAGTGGCTAA AACTGCCTCT GAAATGGTCC TGGCAGATGA CAACTTCTCC 
ACCATCGTGG CTGCTGTCGA GGAGGGGCGG GCAATCTACA ACAATATGAA GCAGTTTATC 
CGCTACCTCA TCTCCTCAAA TGTGGGGGAG GTTGTCTGTA TTTTCCTGAC GGCAGCCCTT 
GGATTCCCTG AGGCTTTAAT TCCTGTCCAG CTGCTCTGGG TCAATCTGGT GACAGACGGC 
CTGCCTGCCA CTGCCCTGGG GTTTAACCCT CCTGATCTAG ACATCATGAA CAAACCACCC 
CGGAACCCGA AGGAACCTCT GATCAGTGGA TGGCTCTTTT TCCGTTACCT GGCCATTGGC 
TGTTATGTTG GCGCTGCTAC CGTGGGTGCT GCTGCATGGT GGTTCATTGC TGCCGACGGA 
GGACCAAGAG TGTCCTTCTA CCAGCTGAGC CACTTCCTAC AGTGTAAAGA TGACAACCCG 
GACTTTGAAG GAGTGGATTG TGCAATCTTT GAATCCCCGT ACCCGATGAC AATGGCGCTG 
TCTGTTCTAG TAACCATAGA GATGTGTAAT GCCCTCAACA GCTTGTCCGA AAACCAGTCC 
CTGCTGAGGA TGCCCCCCTG GGAGAACATC TGGCTGGTGG GCTCTATCTG CCTGTCCATG 
TCCCTCCACT TCCTCATCCT TTACGTGGAA CCTTTGCCAC TTATTTTCCA GATCACACCG 
TTGAATTTGA CCCAGTGGCT AATGGTGCTG AAAATCTCCT TGCCTGTGAT TCTAATGGAT 
GAGACACTCA AGTTTGTGGC CCGCAACTAC CTGGAACCTG CAATACTGGA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003214.1
CDS	204..3197
Translation	MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDSCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGVKQKVMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELSPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKDDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARNYLEPAILE

Target ORF information:

RefSeq Version	NM_001003214.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 (ATP2A2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003214.1

ORF Insert Sequence:

ATGGAGAACG CGCACACAAA GACGGTGGAG GAGGTGCTGG GCCACTTCGG CGTCAACGAG 
AGCACGGGGC TGAGTCTGGA GCAGGTCAAG AAGCTCAAGG AGAGATGGGG CTCCAACGAG 
TTACCGGCCG AAGAAGGAAA AACCTTGCTG GAACTTGTGA TCGAGCAGTT TGAAGACTTA 
CTAGTTCGAA TATTATTGCT GGCAGCGTGT ATATCTTTTG TTTTGGCTTG GTTTGAAGAA 
GGTGAAGAAA CAATTACAGC CTTTGTAGAA CCCTTTGTAA TTTTACTTAT ATTAGTAGCC 
AATGCAATTG TGGGTGTATG GCAGGAGAGA AATGCTGAGA ATGCGATCGA AGCACTTAAG 
GAATATGAGC CTGAAATGGG CAAAGTATAT CGACAGGACA GAAAGAGTGT CCAGCGGATT 
AAAGCTAAAG ACATAGTTCC TGGTGATATT GTAGAAATTG CTGTTGGTGA CAAAGTTCCT 
GCTGATATAA GATTAACATC CATCAAATCT ACGACTCTAA GAGTTGACCA GTCCATTCTC 
ACAGGTGAGT CTGTGTCTGT CATCAAGCAC ACTGACCCGG TCCCAGACCC ACGGGCTGTC 
AATCAAGATA AAAAGAATAT GCTCTTTTCT GGTACAAACA TTGCTGCTGG CAAAGCCATG 
GGAGTGGTAG TGGCAACTGG AGTGAACACA GAAATTGGCA AGATCCGGGA TGAAATGGTA 
GCAACAGAGC AGGAGAGAAC CCCACTCCAG CAGAAACTAG ATGAGTTTGG GGAACAGCTT 
TCCAAAGTCA TCTCCCTGAT TTGCATCGCA GTCTGGATCA TAAACATTGG GCACTTCAAT 
GACCCAGTTC ATGGAGGCTC CTGGATCAGA GGTGCTATTT ACTACTTCAA AATTGCAGTG 
GCCCTGGCTG TGGCAGCCAT TCCTGAAGGT CTGCCTGCTG TCATCACCAC CTGCCTGGCT 
CTTGGAACTC GCAGAATGGC TAAGAAAAAT GCCATTGTTC GAAGCCTCCC TTCTGTGGAA 
ACCCTAGGTT GTACTTCTGT TATCTGCTCA GACAAGACTG GTACACTGAC AACGAACCAG 
ATGTCTGTGT GCAGGATGTT CATTCTGGAC AGAGTTGAAG GTGATAGCTG CTCCCTTAAT 
GAGTTTACCA TTACTGGATC AACATACGCA CCTATTGGAG AAGTGCATAA AGATGATAAA 
CCAGTGAAAT GTCATCAATA TGATGGTCTT GTGGAATTGG CAACCATCTG TGCTCTTTGT 
AATGATTCTG CATTGGATTA CAATGAGGCG AAGGGTGTGT ATGAAAAAGT TGGAGAAGCT 
ACAGAGACTG CTCTCACATG CCTAGTAGAG AAGATGAATG TATTTGATAC CGAATTGAAG 
GGTCTTTCTA AAATAGAGCG AGCAAATGCC TGCAACTCGG TCATTAAGCA GTTGATGAAA 
AAGGAATTTA CTTTGGAGTT TTCACGTGAT AGAAAATCAA TGTCAGTTTA TTGTACACCA 
AACAAACCGA GCCGGACTTC GATGAGCAAA ATGTTTGTGA AGGGGGCTCC TGAAGGTGTC 
ATTGACAGGT GCACCCACAT TCGAGTTGGA AGTACTAAAG TCCCTATGAC CCCAGGCGTC 
AAACAGAAGG TCATGTCTGT CATTCGGGAA TGGGGTAGCG GCAGCGACAC ACTGCGGTGC 
CTGGCCCTGG CCACCCACGA CAACCCTCTG AGAAGAGAAG AAATGAACCT TGAGGACTCT 
GCCAACTTTA TTAAATATGA GACCAATCTG ACTTTCGTTG GATGCGTGGG CATGCTGGAT 
CCTCCAAGGA TTGAAGTGGC CTCCTCTGTA AAGCTGTGCC GGCAAGCAGG CATCCGAGTC 
ATTATGATCA CAGGAGACAA CAAGGGCACG GCAGTGGCCA TCTGTCGGCG CATTGGCATC 
TTTGGACAGG ACGAAGATGT GACGTCAAAG GCTTTTACAG GCCGGGAGTT TGATGAGCTC 
AGTCCTTCAG CCCAGAGGGA TGCCTGCTTG AATGCCCGCT GTTTTGCTCG AGTCGAACCT 
TCCCACAAGT CAAAAATTGT AGAATTCCTT CAGTCTTTTG ATGAGATTAC AGCCATGACT 
GGGGATGGTG TGAATGATGC TCCTGCCCTG AAGAAATCGG AGATCGGCAT TGCCATGGGC 
TCGGGCACAG CAGTGGCTAA AACTGCCTCT GAAATGGTCC TGGCAGATGA CAACTTCTCC 
ACCATCGTGG CTGCTGTCGA GGAGGGGCGG GCAATCTACA ACAATATGAA GCAGTTTATC 
CGCTACCTCA TCTCCTCAAA TGTGGGGGAG GTTGTCTGTA TTTTCCTGAC GGCAGCCCTT 
GGATTCCCTG AGGCTTTAAT TCCTGTCCAG CTGCTCTGGG TCAATCTGGT GACAGACGGC 
CTGCCTGCCA CTGCCCTGGG GTTTAACCCT CCTGATCTAG ACATCATGAA CAAACCACCC 
CGGAACCCGA AGGAACCTCT GATCAGTGGA TGGCTCTTTT TCCGTTACCT GGCCATTGGC 
TGTTATGTTG GCGCTGCTAC CGTGGGTGCT GCTGCATGGT GGTTCATTGC TGCCGACGGA 
GGACCAAGAG TGTCCTTCTA CCAGCTGAGC CACTTCCTAC AGTGTAAAGA TGACAACCCG 
GACTTTGAAG GAGTGGATTG TGCAATCTTT GAATCCCCGT ACCCGATGAC AATGGCGCTG 
TCTGTTCTAG TAACCATAGA GATGTGTAAT GCCCTCAACA GCTTGTCCGA AAACCAGTCC 
CTGCTGAGGA TGCCCCCCTG GGAGAACATC TGGCTGGTGG GCTCTATCTG CCTGTCCATG 
TCCCTCCACT TCCTCATCCT TTACGTGGAA CCTTTGCCAC TTATTTTCCA GATCACACCG 
TTGAATTTGA CCCAGTGGCT AATGGTGCTG AAAATCTCCT TGCCTGTGAT TCTAATGGAT 
GAGACACTCA AGTTTGTGGC CCGCAACTAC CTGGAACCTG CAATACTGGA GTAA