GenScript Target Enrichment Solutions

• Hybridization-based enrichment

  Column synthesized 5’-biotinylated ssDNA capture probes for lab developed test scale-up

  Column synthesized ssDNA probe panel is a good choice once you have done small scale test of your target enrichment panel and are ready to scale up to test more populations. The column synthesized ssDNA panel are consist of individually synthesized DNA oligos, purified via RPC, HPLC+, inspected under stringent QC to offer superior purity, consistency and uniformity.

  Types	Length	Purification method	Deliverables
  Capture probes with 5’ biotin	80-150 nt	Desalt & Ultrafiltration HPLC+	Tubes or plates Lyophilized COA document

  Please find more customized QC information in Oligo Quality Control Service>>.

  Column based Custom Capture Probe Panel Performance and specifications: Read More »

  • Highly stable biotin modification

    

    

    Stability of biotin modification with increasing days in storage and number of freeze-thaws.

  • Uniform pooling ability

    

    TECAN Liquid Handling Platforms

    MS (deviation≤0.05%) & quantification (deviation≤10%) for each sequence before pooling

    Up to ten thousands oligos per pool without losing sequence to request concertation by high-precision automatic equipment

  Order:

  For quote, please download the Quick Quotation Requrest Form and send the form to the email address: oligo@genscript.com. Our technical account managers will contact you in 24 hours.

• Amplicon-based enrichment

  Custom Multiplex PCR Primers, fully customizable for your convenience

  Similar to column synthesized capture probes, our multiplex PCR primers offers high purity, low contamination primers that delivers in tube or plates for your convenience.

  Length	Purification method	Deliverables
  15-150 nt	Desalt & Ultrafiltration HPLC+	Tubes or plates Lyophilized COA document

  Please find more customized QC information in Oligo Quality Control Service>>.

  Column based Multiplex PCR Primers Panel Performance and specifications: Read More »

  • Precise quantification and minimal lot-to-lot variation

    

  • Uniform pooling ability

    

    TECAN Liquid Handling Platforms

    MS (deviation≤0.05%) & quantification (deviation≤10%) for each sequence before pooling

    Up to ten thousands oligos per pool without losing sequence to request concertation by high-precision automatic equipment

  Order:

  For quote, please download the Quick Quotation Requrest Form and send the form to the email address: oligo@genscript.com. Our technical account managers will contact you in 24 hours.

• NGS Adapter

  Adapter with cross-contamination as low as 0.01%

  For NGS library construction, whether the sample is directly fragmented or the target region is obtained by hybridization capture, multiplex PCR amplification, etc., it is necessary to add adapter to each sample fragment by Enzyme-linked method or transposase method. GenScript provide adapter with low cross-contamination to avoid mismatch.

  Types	Length	Purification method	Deliverables
  NGS Adapter	15-80 nt	HPLC+ Desalt	Tubes or plates Lyophilized COA document

  Please find more customized QC information in Oligo Quality Control Service>>.

  NGS Adapter Performance and specifications: Read More »

  • Low cross-contamination rate

    

  • Stable modification

    

    

    Stability of biotin modification with increasing days in storage and number of freeze-thaws.

  Order:

  For quote, please download the Quick Quotation Requrest Form and send the form to the email address: oligo@genscript.com. Our technical account managers will contact you in 24 hours.

Case Studies

• NGS Adapter

  Cross-contamination of HPLC+ is monitored every quarter.

  

  * Due to varying sequences and detection conditions, GenScript cannot ensure each oligo's cross-contamination rate is below 0.01% on your end. Please inform us during inquiry if cross-contamination rate is critical factor for you.