Custom DNA Oligo Synthesis Services

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Overview

GenScript offers up to 218 nt DNA oligo synthesis and comprehensive 200+ modifications & labeling to meet research needs in biology, diagnostics (qPCR & NGS), and drug discovery. GenScript provide high purity oligo with optimized PAGE+/HPLC+ etc., processes under ISO 13485 for MDx kit.

DNA oligos produced by GenScript's state-of-the-art oligo-synthesizer have substantial purity with low truncated sequences. Each oligo is meticulously monitored during synthesis and controlled according to GenScript's stringent quality assurance and quality control standards. The final product is identified by mass spectrum and its purity is analyzed by high throughput capillary gel electrophoresis or HPLC based on the purification option.

We specialize in oligonucleotides labeled by fluorescent or non-fluorescent dyes, quencher pairs or electrochemicals for qualitative and quantitative detection.

Advantages

Powerful capacity

up to 218 nt, kg delivery ability

Cost-effective

Save up to 40% cost than competitors

Expert in modifications

Support 200+ types and highly modified oligos

Qualifications

ISO 13485, controlled areas

Online Ordering

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Oligo Synthesis

Announcing New, Lower Pricing on Our High Performance DNA & RNA Oligos!

Get premium quality oligos at up to 40% lower cost- without compromising on performance, modifications, or scalability.
Save BIG on all orders while taking advantage of our recent capability upgrades, including purity improvements and shorter TAT for select oligo types and extended length capacity for RNA (up to 266 nt)!

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Services

Service Name	Length	Quantity	Purification	QC	Application
DNA Oligo	2-218 nt *	Up to kg	Desalt, ePAGE, PAGE^#,HPLC PAGE+^#, HPLC+, Dual HPLC, Dual PAGE & HPLC	COA MS/HPLC/CGE report is optional	qPCR, NGS, PCR amplification, DNA Sequencing, site-directed mutagenesis etc

* 218nt is available for HPLC grade, other purification methods please inquire.
# GenScript recommends PAGE/PAGE+ purification for primers of 151-200 nt. For PAGE-purified primers shorter than 150 nt, if you prioritize cost-effectiveness and faster turnaround times, you can choose ePAGE; if you prioritize higher purity, you can choose HPLC or HPLC+.

Please pay attention to base code when place order.
Please refer to the purification method selection guide.
Please find more customized QC information in Oligo Quality Control Service>>.

Modification/Labeling/ Multiple Labeling: click & view the modification list>>

Modified Bases	Phosphorothioates	Phosphorylation	Spacers
Amino Linkers	Disulfide Linkers	Biotin	Quenchers
Fluorophores	Electrochemical Labeling

GenScript is expert in multiple labeling within a single oligo. Please complete a quote for multiple labeling.

For quotations, please use our secured Online Quotation/Ordering system. However, you may also contact us by email, phone (1-732-885-9188) or fax (1-732-210-0262).

Orders can be placed directly through our secured Online Quotation/Ordering system with a formal PO (Purchase Order) or credit card.

For batch orders, please download and complete our Quick Quotation Request and send it to us via email or fax.

Our customer service representatives are available 24 hours Monday through Friday. You may contact us anytime for assistance.

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Cases

Case 1. Superior quality! Precise MW, high purity, excellent batch-to-batch consistency

HPLC: purity ≥ 90%

MS: molecular weight deviation ≤ 0.05%

Batch-to-batch stability of purity

Batch-to-batch stability of molecular weight
Case 2. Up to 218nt! Expert in long chain chemosynthetic DNA oligo

218nt chemosynthetic DNA oligo, HPLC purification
Case 3. Strict Control of Exogenous Contamination for qPCR oligos
- Strictly control exogenous contamination in monitored clean room
- Stable quality & Ct value and excellent batch-to-batch consistency
- High precision with low CV value & high sensitivity with high detection rate
Case 4. Strict Control of Cross-Contamination for NGS oligos
- Adapter: Low cross-contamination rate as low as 0.01%
- Capture Probe: Stable modifications, uniform quantification & precise pooling
- Multiple PCR oligo: Uniform quantification & precise pooling
- Blocker: High purity and blocking efficiency
* The ≤0.01% cross-contamination rate is not our guaranteed QC standard. If the cross-contamination rate is critical to your application, please inform us so we can implement stricter processes to achieve a lower rate.