Gene Symbol | IFIH1 |
Entrez Gene ID | 100101927 |
Full Name | interferon induced with helicase C domain 1 |
Synonyms | MDA5 |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
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ORF » Species Summary » Sus scrofa » IFIH1 cDNA ORF clone
Gene Symbol | IFIH1 |
Entrez Gene ID | 100101927 |
Full Name | interferon induced with helicase C domain 1 |
Synonyms | MDA5 |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
mRNA | Protein | Name |
---|---|---|
NM_001100194.1 | NP_001093664.1 | interferon-induced helicase C domain-containing protein 1 |
XM_005671881.2 | XP_005671938.1 | interferon-induced helicase C domain-containing protein 1 isoform X1 |
XM_005671881.3 | XP_005671938.1 | interferon-induced helicase C domain-containing protein 1 isoform X1 |
Interferon-Inducible Oligoadenylate Synthetase-Like Protein Acts as an Antiviral Effector against Classical Swine Fever Virus via the MDA5-Mediated Type I Interferon-Signaling Pathway.
Li LF, Yu J, Zhang Y, Yang Q, Li Y, Zhang L, Wang J, Li S, Luo Y, Sun Y, Qiu HJ
Journal of virology91(11)(2017 06)
Classical swine fever virus triggers RIG-I and MDA5-dependent signaling pathway to IRF-3 and NF-κB activation to promote secretion of interferon and inflammatory cytokines in porcine alveolar macrophages.
Dong XY, Liu WJ, Zhao MQ, Wang JY, Pei JJ, Luo YW, Ju CM, Chen JD
Virology journal10286(2013 Sep)
Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling.
Motz C, Schuhmann KM, Kirchhofer A, Moldt M, Witte G, Conzelmann KK, Hopfner KP
Science (New York, N.Y.)339(6120)690-3(2013 Feb)
Differences in distribution of single nucleotide polymorphisms among intracellular pattern recognition receptors in pigs.
Kojima-Shibata C, Shinkai H, Morozumi T, Jozaki K, Toki D, Matsumoto T, Kadowaki H, Suzuki E, Uenishi H
Immunogenetics61(2)153-60(2009 Feb)
PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences.
Uenishi H, Eguchi-Ogawa T, Shinkai H, Okumura N, Suzuki K, Toki D, Hamasima N, Awata T
Nucleic acids research35(Database issue)D650-3(2007 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following IFIH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IFIH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSe23440 | |
Clone ID Related Accession (Same CDS sequence) | XM_005671881.2 , XM_005671881.3 | |
Accession Version | XM_005671881.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2931bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1441814400000 | |
Organism | Sus scrofa(Pig) | |
Product | interferon-induced helicase C domain-containing protein 1 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003612233.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005671881.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGTCGG ATGGGTATTC CGCGGACCAG AATTTCTGCT ATCTCATCTC GTGTTTCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005671938.1 |
CDS | 372..3302 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCGTCGG ATGGGTATTC CGCGGACCAG AATTTCTGCT ATCTCATCTC GTGTTTCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe23440 | |
Clone ID Related Accession (Same CDS sequence) | XM_005671881.2 , XM_005671881.3 | |
Accession Version | XM_005671881.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2931bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1494518400000 | |
Organism | Sus scrofa(pig) | |
Product | interferon-induced helicase C domain-containing protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010457.5) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 13, 2017 this sequence version replaced XM_005671881.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGTCGG ATGGGTATTC CGCGGACCAG AATTTCTGCT ATCTCATCTC GTGTTTCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005671938.1 |
CDS | 333..3263 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCGTCGG ATGGGTATTC CGCGGACCAG AATTTCTGCT ATCTCATCTC GTGTTTCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe28507 | |
Clone ID Related Accession (Same CDS sequence) | NM_001100194.1 | |
Accession Version | NM_001100194.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3072bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1501344000000 | |
Organism | Sus scrofa(pig) | |
Product | interferon-induced helicase C domain-containing protein 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EU006039.1. ##Evidence-Data-START## Transcript exon combination :: EU006039.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1487420, SAMEA1876824 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGTCGTCGG ATGGGTATTC CGCGGACCAG AATTTCTGCT ATCTCATCTC GTGTTTCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001093664.1 |
CDS | 1..3072 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCGTCGG ATGGGTATTC CGCGGACCAG AATTTCTGCT ATCTCATCTC GTGTTTCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Interferon-Inducible Oligoadenylate Synthetase-Like Protein Acts as an Antiviral Effector against Classical Swine Fever Virus via the MDA5-Mediated Type I Interferon-Signaling Pathway. |
Classical swine fever virus triggers RIG-I and MDA5-dependent signaling pathway to IRF-3 and NF-κB activation to promote secretion of interferon and inflammatory cytokines in porcine alveolar macrophages. |
Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling. |
Differences in distribution of single nucleotide polymorphisms among intracellular pattern recognition receptors in pigs. |
PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. |