Abcb11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcb11
Entrez Gene ID	83569
Full Name	ATP binding cassette subfamily B member 11
Synonyms	Bsep,Spgp
General protein information	Preferred Names ATP binding cassette subfamily B member 11 Names bile salt export pump ATP-binding cassette sub-family B member 11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 sister of P-glycoprotein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q21
Summary	acts as an ATP-dependent bile salt export pump; transports taurochenodeoxycholate, taurocholate, and other bile salts [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031760.1	NP_113948.1	bile salt export pump

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ABCB11	XP_526100.2
Bos taurus (cattle)	ABCB11	NP_001179632.1
Rattus norvegicus (Norway rat)	Abcb11	NP_113948.1
Mus musculus (house mouse)	Abcb11	NP_066302.2
Gallus gallus (chicken)	ABCB11	XP_004942815.1
Danio rerio (zebrafish)	abcb11b	XP_003199513.2
Homo sapiens (human)	ABCB11	NP_003733.2
Macaca mulatta (Rhesus monkey)	ABCB11	XP_001097771.2
Canis lupus familiaris (dog)	ABCB11	NP_001137404.1
Xenopus tropicalis (tropical clawed frog)	LOC100489579	XP_004917764.1

Gene Ontology
Bibliography

Related articles in PubMed

Tsumura-Suzuki obese diabetic mice-derived hepatic tumors closely resemble human hepatocellular carcinomas in metabolism-related genes expression and bile acid accumulation.
Takahashi T, Deuschle U, Taira S, Nishida T, Fujimoto M, Hijikata T, Tsuneyama K
Hepatology international12(3)254-261(2018 May)

Diagnosis of cirrhosis in patients with chronic hepatitis C genotype 4: Role of ABCB11 genotype polymorphism and plasma bile acid levels.
Besheer T, Arafa M, El-Maksoud MA, Elalfy H, Hasson A, Zalata K, Elkashef W, Elshahawy H, Raafat D, Elemshaty W, Elsayed E, Zaghloul H, Razek AA, El-Bendary M
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology29(3)299-307(2018 05)

Dysregulation of BSEP and MRP2 May Play an Important Role in Isoniazid-Induced Liver Injury via the SIRT1/FXR Pathway in Rats and HepG2 Cells.
Qu X, Zhang Y, Zhang S, Zhai J, Gao H, Tao L, Song Y
Biological & pharmaceutical bulletin41(8)1211-1218(2018)

Adenovirus-mediated human aquaporin-1 expression in hepatocytes improves lipopolysaccharide-induced cholestasis.
Marrone J, Danielli M, Gaspari CI, Marinelli RA
IUBMB life69(12)978-984(2017 12)

Influence of ABCB11 and HNF4α genes on daclatasvir plasma concentration: preliminary pharmacogenetic data from the Kineti-C study.
Cusato J, De Nicolò A, Boglione L, Favata F, Ariaudo A, Mornese Pinna S, Guido F, Avataneo V, Carcieri C, Cariti G, Di Perri G, D'Avolio A
The Journal of antimicrobial chemotherapy72(10)2846-2849(2017 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Abcb11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcb11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13598	NM_031760.1 Latest version!	Rattus norvegicus ATP binding cassette subfamily B member 11 (Abcb11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcb11 ( NM_031760.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113948.1 Rattus norvegicus ATP binding cassette subfamily B member 11 (Abcb11), mRNA.

Price & Availability↑

CloneID	ORa13598
Clone ID Related Accession (Same CDS sequence)	NM_031760.1
Accession Version	NM_031760.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	bile salt export pump
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U69487.1. On Dec 17, 2003 this sequence version replaced XM_346681.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U69487.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689594, SAMEA2689595 [ECO:0000350] ##Evidence-Data-END##

ATGTCTGACT CAGTGATTCT TCGCAGCGTG AAGAAATTTG GAGAGGAGAA TCATGCTTTC 
GAATCAGATG GATCACATAA CAATGATAAG AAATCAAGGT TACAAGATAA GATGAAGGAG 
GGAGACATTC GAGTTGGCTT CTTTGAACTG TTTCGATTTT CTTCATCAAA AGACATCTGG 
CTGATGCTTA TGGGAGGCGT ATGCGCATTG CTACATGGAA TGGCCCAGCC AGGCATACTT 
ATTATTTTTG GTATAATGAC AGATATTTTT ATTAAATATG ACATTGAAAG GCAAGAACTC 
GAGATACCAG GAAAAGCGTG TGTGAATAAC ACCATTGTAT GGATCAACAG CTCCTTCCAC 
CAGAACATGA CAAACGGAAC AGTCTGTGGG TTGGTGGACA TTGAAAGTGA AATGATCAAA 
TTCTCTGGCA TCTACGCAGG AGTCGGCATG ACCGTACTTA TCCTTGGATA CTTTCAAATA 
AGGTTATGGG TCATCACTGG GGCTCGTCAG ATAAGGAGAA TGAGGAAAAT TTACTTCCGG 
AGAATAATGA GAATGGAAAT TGGGTGGTTC GACTGCACTT CTGTGGGAGA GCTGAATTCA 
AGGTTTGCTG ATGATATTGA AAAAATCAAT GACGCCATTG CCGACCAGTT GGCTCATTTC 
CTCCAGCGCA TGTCGACGGC TATGTGTGGG TTACTTTTAG GGTTCTACAG GGGTTGGAAA 
CTAACCTTGG TGATTCTTGC TGTCAGCCCT CTCATTGGCA TTGGGGCAGC CGTCATAGGT 
CTGAGTATAG CCAAGTTCAC GGAGCTTGAG TTGAAGGCTT ATGCCAAAGC GGGGTCTATT 
GCTGATGAAG TCCTCTCATC TATTCGAACA GTGGCCGCTT TTGGTGGTGA GAACAAAGAG 
GTTGAAAGGT ATGAGAAAAA TCTTGTGTTT GCCCAGCGCT GGGGAATTTG GAAAGGAATG 
GTGATGGGCT TCTTCACTGG GTACATGTGG TGTCTCATTT TCTTCTGTTA TGCACTGGCC 
TTCTGGTATG GTTCCACACT TGTCCTAGAT GAAGAAGAGT ATACACCAGG GACACTGGTC 
CAGATTTTCC TCTGTGTCAT ATTAGCAGCT ATGAATATTG GCCATGCATC TTCTTGCTTG 
GAAATCTTCT CCACTGGGTG TTCAGCAGCT ACCAATATTT TTCAAACAAT AGACAGGCAA 
CCTGTCATTG ACTGCATGTC AGGAGACGGC TACAAGCTAG ACCGAATCAA GGGTGAAATT 
GAGTTCCACA ATGTGACCTT CCATTATCCT TCTAGACCGG ACGTGAAGAT TTTAGATAAC 
CTCAGCATGG TCATAAAGCC AGGGGAAACG ACGGCTCTGG TGGGATCCAG TGGGGCTGGG 
AAGAGTACAG CATTACAGCT CATTCAGAGA TTCTATGACC CCTGTGAAGG CATGGTGACT 
CTGGACGGCC ATGACATTCG CTCTCTTAAC ATCCGGTGGC TGAGAGATCA AATCGGGATC 
GTGGAACAGG AGCCCGTTCT GTTCTCCACC ACTATCGCAG AAAACATCCG TTTTGGCAGA 
GAAGATGCAA CAATGGAAGA CATAGTCCAA GCTGCCAAGG ATGCTAATGC ATACAACTTC 
ATTATGGCCC TGCCGCAGCA ATTTGACACC CTTGTTGGAG AAGGAGGAGG CCAGATGAGT 
GGTGGTCAGA AGCAAAGAGT AGCCATTGCC CGAGCCCTCA TACGGAATCC CAAGATCTTG 
CTTCTGGATA TGGCTACCTC AGCACTGGAC AATGAGAGTG AAGCTAGAGT ACAAGAAGCA 
TTGAATAAGA TCCAACATGG GCATACAATC ATCTCAGTTG CCCATCGCCT GTCAACAGTC 
AGAGCTGCAG ATGTGATCAT TGGGTTTGAG CATGGAGTAG CTGTGGAAAG AGGCACCCAT 
GAAGAGCTGC TAGAAAGAAA AGGTGTCTAC TTCATGCTTG TGACCCTGCA AAGCCAAGGA 
GATAATGCTC ACAAAGAAAC GAGCATAATG GGGAAAGATG CGACGGAAGG TGGCACCCTT 
GAGAGGACCT TTTCCAGAGG CAGCTATCGG GATAGTTTAA GAGCTTCGAT CCGGCAACGC 
TCCAAGTCTC AGCTGTCTCT TCTGACACAT GACCCTCCAC TGGCTGTTGC TGATCACAAA 
TCCTCTTACA AAGACAGCAA GGACAATGAC GTGCTTGTGG AAGAAGTTGA ACCTGCCCCA 
GTTAGGAGGA TTCTAAAATA CAACATTCCA GAATGGCACT ACATTCTGGT AGGATCTTTG 
AGTGCAGCCA TTAATGGGGC AGTCACACCC ATCTACTCCC TTTTATTCAG CCAGCTCCTT 
GGGACTTTTT CACTCCTCGA TAAAGAACAA CAAAGGTCAG AGATTCACAG CATGTGTCTG 
TTCTTTGTCA TCCTGGGCTG TGTATCCATT TTCACACAAT TTCTGCAGGG TTACACTTTT 
GCCAAATCCG GAGAGCTCCT CACAAAGAGG CTGCGGAAAT TTGGTTTCAA GGCAATGTTA 
GGACAAGATA TCGGCTGGTT CGATGACCTC AGAAATAATC CTGGAGTACT GACGACTAGG 
CTTGCTACAG ATGCTTCCCA AGTTCAAGGG GCTACTGGCT CTCAAGTTGG AATGATGGTC 
AATTCCTTCA CTAACATCAT TGCGGCCTTG CTGATTGCCT TCTTCTTTAG CTGGAAGCTC 
AGTCTGATTA TAACGATCTT CTTCCCCTTT CTGGCTTTAT CGGGAGCTGT ACAGACAAAA 
ATGTTGACGG GATTCGCTTC TCAAGACAAG CAAGCTCTGG AGAAGGCTGG TCAGATCACC 
AGCGAAGCCC TCAGCAATAT CCGCACAGTT GCTGGGATTG GAGTGGAGGG AAGATTTATT 
AAAGCATTTG AGGTTGAGCT CCAGACATCA TACAAGACTG CTGTCAGGAA GGCGAATATC 
TATGGACTCT GCTTTGCCTT TTCCCAGGGG ATAGCATTTC TTGCAAATTC CGCTGCCTAT 
AGATATGGAG GTTACTTAAT AGCCTACGAA GGTCTGGGCT TCAGCCACGT TTTCAGGGTG 
GTCTCTTCAG TTGCATTGAG TGCAACAGCC GTTGGAAGAA CATTCTCTTA TACTCCGAGC 
TATGCCAAAG CTAAAATATC AGCTGCACGC TTTTTTCAAC TGCTAGATCG GAAACCTCCA 
ATTAATGTGT ACAGTGAAGC AGGTGAAAAA TGGGACAACT TCCAAGGGAA GATTGATTTT 
ATTGACTGTA AATTTACGTA TCCTTCTCGA CCCGATATTC AAGTTCTGAA TGGTCTCTCA 
GTATCTGTTA ATCCTGGGCA GACGCTGGCA TTTGTTGGAA GCAGTGGGTG TGGCAAAAGC 
ACCAGCATTC AGCTGTTGGA ACGGTTCTAT GATCCCGATC AGGGAACTGT GATGATAGAT 
GGTCATGACA GCAAAAAAGT CAACATTCAG TTCCTCCGTT CCAACATCGG GATTGTCTCC 
CAGGAGCCAG TGCTGTTTGA CTGTAGCATA ATGGACAACA TCAAGTACGG GGACAACACT 
AAAGAGATCT CCGTGGAGAG AGCCATAGCT GCTGCAAAGC AGGCTCAGCT GCATGACTTC 
GTCATGTCGC TCCCAGAGAA ATATGAAACT AATGTTGGGA TCCAGGGCTC TCAGCTCTCT 
CGTGGAGAGA AACAACGCAT TGCTATTGCT CGGGCCATTG TGCGAGATCC TAAAATCTTA 
CTACTGGATG AAGCTACGTC TGCCCTAGAC ACAGAAAGTG AAAAGACAGT GCAGACTGCT 
CTGGACAAAG CCAGAGAGGG TCGGACCTGC ATTGTCATTG CTCATCGTTT GTCCACCATC 
CAGAACTCAG ATATCATTGC TGTCGTGTCA CAAGGAGTGG TGATTGAAAA AGGGACCCAT 
GAGAAACTGA TGGCCCAGAA GGGAGCCTAC TACAAGCTGG TCATCACTGG AGCCCCCATC 
AGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113948.1
CDS	263..4228
Translation	MSDSVILRSVKKFGEENHAFESDGSHNNDKKSRLQDKMKEGDIRVGFFELFRFSSSKDIWLMLMGGVCALLHGMAQPGILIIFGIMTDIFIKYDIERQELEIPGKACVNNTIVWINSSFHQNMTNGTVCGLVDIESEMIKFSGIYAGVGMTVLILGYFQIRLWVITGARQIRRMRKIYFRRIMRMEIGWFDCTSVGELNSRFADDIEKINDAIADQLAHFLQRMSTAMCGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSIAKFTELELKAYAKAGSIADEVLSSIRTVAAFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFWYGSTLVLDEEEYTPGTLVQIFLCVILAAMNIGHASSCLEIFSTGCSAATNIFQTIDRQPVIDCMSGDGYKLDRIKGEIEFHNVTFHYPSRPDVKILDNLSMVIKPGETTALVGSSGAGKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRFGREDATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEARVQEALNKIQHGHTIISVAHRLSTVRAADVIIGFEHGVAVERGTHEELLERKGVYFMLVTLQSQGDNAHKETSIMGKDATEGGTLERTFSRGSYRDSLRASIRQRSKSQLSLLTHDPPLAVADHKSSYKDSKDNDVLVEEVEPAPVRRILKYNIPEWHYILVGSLSAAINGAVTPIYSLLFSQLLGTFSLLDKEQQRSEIHSMCLFFVILGCVSIFTQFLQGYTFAKSGELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGVLTTRLATDASQVQGATGSQVGMMVNSFTNIIAALLIAFFFSWKLSLIITIFFPFLALSGAVQTKMLTGFASQDKQALEKAGQITSEALSNIRTVAGIGVEGRFIKAFEVELQTSYKTAVRKANIYGLCFAFSQGIAFLANSAAYRYGGYLIAYEGLGFSHVFRVVSSVALSATAVGRTFSYTPSYAKAKISAARFFQLLDRKPPINVYSEAGEKWDNFQGKIDFIDCKFTYPSRPDIQVLNGLSVSVNPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKKVNIQFLRSNIGIVSQEPVLFDCSIMDNIKYGDNTKEISVERAIAAAKQAQLHDFVMSLPEKYETNVGIQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQTALDKAREGRTCIVIAHRLSTIQNSDIIAVVSQGVVIEKGTHEKLMAQKGAYYKLVITGAPIS

Target ORF information:

RefSeq Version	NM_031760.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily B member 11 (Abcb11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031760.1

ORF Insert Sequence:

ATGTCTGACT CAGTGATTCT TCGCAGCGTG AAGAAATTTG GAGAGGAGAA TCATGCTTTC 
GAATCAGATG GATCACATAA CAATGATAAG AAATCAAGGT TACAAGATAA GATGAAGGAG 
GGAGACATTC GAGTTGGCTT CTTTGAACTG TTTCGATTTT CTTCATCAAA AGACATCTGG 
CTGATGCTTA TGGGAGGCGT ATGCGCATTG CTACATGGAA TGGCCCAGCC AGGCATACTT 
ATTATTTTTG GTATAATGAC AGATATTTTT ATTAAATATG ACATTGAAAG GCAAGAACTC 
GAGATACCAG GAAAAGCGTG TGTGAATAAC ACCATTGTAT GGATCAACAG CTCCTTCCAC 
CAGAACATGA CAAACGGAAC AGTCTGTGGG TTGGTGGACA TTGAAAGTGA AATGATCAAA 
TTCTCTGGCA TCTACGCAGG AGTCGGCATG ACCGTACTTA TCCTTGGATA CTTTCAAATA 
AGGTTATGGG TCATCACTGG GGCTCGTCAG ATAAGGAGAA TGAGGAAAAT TTACTTCCGG 
AGAATAATGA GAATGGAAAT TGGGTGGTTC GACTGCACTT CTGTGGGAGA GCTGAATTCA 
AGGTTTGCTG ATGATATTGA AAAAATCAAT GACGCCATTG CCGACCAGTT GGCTCATTTC 
CTCCAGCGCA TGTCGACGGC TATGTGTGGG TTACTTTTAG GGTTCTACAG GGGTTGGAAA 
CTAACCTTGG TGATTCTTGC TGTCAGCCCT CTCATTGGCA TTGGGGCAGC CGTCATAGGT 
CTGAGTATAG CCAAGTTCAC GGAGCTTGAG TTGAAGGCTT ATGCCAAAGC GGGGTCTATT 
GCTGATGAAG TCCTCTCATC TATTCGAACA GTGGCCGCTT TTGGTGGTGA GAACAAAGAG 
GTTGAAAGGT ATGAGAAAAA TCTTGTGTTT GCCCAGCGCT GGGGAATTTG GAAAGGAATG 
GTGATGGGCT TCTTCACTGG GTACATGTGG TGTCTCATTT TCTTCTGTTA TGCACTGGCC 
TTCTGGTATG GTTCCACACT TGTCCTAGAT GAAGAAGAGT ATACACCAGG GACACTGGTC 
CAGATTTTCC TCTGTGTCAT ATTAGCAGCT ATGAATATTG GCCATGCATC TTCTTGCTTG 
GAAATCTTCT CCACTGGGTG TTCAGCAGCT ACCAATATTT TTCAAACAAT AGACAGGCAA 
CCTGTCATTG ACTGCATGTC AGGAGACGGC TACAAGCTAG ACCGAATCAA GGGTGAAATT 
GAGTTCCACA ATGTGACCTT CCATTATCCT TCTAGACCGG ACGTGAAGAT TTTAGATAAC 
CTCAGCATGG TCATAAAGCC AGGGGAAACG ACGGCTCTGG TGGGATCCAG TGGGGCTGGG 
AAGAGTACAG CATTACAGCT CATTCAGAGA TTCTATGACC CCTGTGAAGG CATGGTGACT 
CTGGACGGCC ATGACATTCG CTCTCTTAAC ATCCGGTGGC TGAGAGATCA AATCGGGATC 
GTGGAACAGG AGCCCGTTCT GTTCTCCACC ACTATCGCAG AAAACATCCG TTTTGGCAGA 
GAAGATGCAA CAATGGAAGA CATAGTCCAA GCTGCCAAGG ATGCTAATGC ATACAACTTC 
ATTATGGCCC TGCCGCAGCA ATTTGACACC CTTGTTGGAG AAGGAGGAGG CCAGATGAGT 
GGTGGTCAGA AGCAAAGAGT AGCCATTGCC CGAGCCCTCA TACGGAATCC CAAGATCTTG 
CTTCTGGATA TGGCTACCTC AGCACTGGAC AATGAGAGTG AAGCTAGAGT ACAAGAAGCA 
TTGAATAAGA TCCAACATGG GCATACAATC ATCTCAGTTG CCCATCGCCT GTCAACAGTC 
AGAGCTGCAG ATGTGATCAT TGGGTTTGAG CATGGAGTAG CTGTGGAAAG AGGCACCCAT 
GAAGAGCTGC TAGAAAGAAA AGGTGTCTAC TTCATGCTTG TGACCCTGCA AAGCCAAGGA 
GATAATGCTC ACAAAGAAAC GAGCATAATG GGGAAAGATG CGACGGAAGG TGGCACCCTT 
GAGAGGACCT TTTCCAGAGG CAGCTATCGG GATAGTTTAA GAGCTTCGAT CCGGCAACGC 
TCCAAGTCTC AGCTGTCTCT TCTGACACAT GACCCTCCAC TGGCTGTTGC TGATCACAAA 
TCCTCTTACA AAGACAGCAA GGACAATGAC GTGCTTGTGG AAGAAGTTGA ACCTGCCCCA 
GTTAGGAGGA TTCTAAAATA CAACATTCCA GAATGGCACT ACATTCTGGT AGGATCTTTG 
AGTGCAGCCA TTAATGGGGC AGTCACACCC ATCTACTCCC TTTTATTCAG CCAGCTCCTT 
GGGACTTTTT CACTCCTCGA TAAAGAACAA CAAAGGTCAG AGATTCACAG CATGTGTCTG 
TTCTTTGTCA TCCTGGGCTG TGTATCCATT TTCACACAAT TTCTGCAGGG TTACACTTTT 
GCCAAATCCG GAGAGCTCCT CACAAAGAGG CTGCGGAAAT TTGGTTTCAA GGCAATGTTA 
GGACAAGATA TCGGCTGGTT CGATGACCTC AGAAATAATC CTGGAGTACT GACGACTAGG 
CTTGCTACAG ATGCTTCCCA AGTTCAAGGG GCTACTGGCT CTCAAGTTGG AATGATGGTC 
AATTCCTTCA CTAACATCAT TGCGGCCTTG CTGATTGCCT TCTTCTTTAG CTGGAAGCTC 
AGTCTGATTA TAACGATCTT CTTCCCCTTT CTGGCTTTAT CGGGAGCTGT ACAGACAAAA 
ATGTTGACGG GATTCGCTTC TCAAGACAAG CAAGCTCTGG AGAAGGCTGG TCAGATCACC 
AGCGAAGCCC TCAGCAATAT CCGCACAGTT GCTGGGATTG GAGTGGAGGG AAGATTTATT 
AAAGCATTTG AGGTTGAGCT CCAGACATCA TACAAGACTG CTGTCAGGAA GGCGAATATC 
TATGGACTCT GCTTTGCCTT TTCCCAGGGG ATAGCATTTC TTGCAAATTC CGCTGCCTAT 
AGATATGGAG GTTACTTAAT AGCCTACGAA GGTCTGGGCT TCAGCCACGT TTTCAGGGTG 
GTCTCTTCAG TTGCATTGAG TGCAACAGCC GTTGGAAGAA CATTCTCTTA TACTCCGAGC 
TATGCCAAAG CTAAAATATC AGCTGCACGC TTTTTTCAAC TGCTAGATCG GAAACCTCCA 
ATTAATGTGT ACAGTGAAGC AGGTGAAAAA TGGGACAACT TCCAAGGGAA GATTGATTTT 
ATTGACTGTA AATTTACGTA TCCTTCTCGA CCCGATATTC AAGTTCTGAA TGGTCTCTCA 
GTATCTGTTA ATCCTGGGCA GACGCTGGCA TTTGTTGGAA GCAGTGGGTG TGGCAAAAGC 
ACCAGCATTC AGCTGTTGGA ACGGTTCTAT GATCCCGATC AGGGAACTGT GATGATAGAT 
GGTCATGACA GCAAAAAAGT CAACATTCAG TTCCTCCGTT CCAACATCGG GATTGTCTCC 
CAGGAGCCAG TGCTGTTTGA CTGTAGCATA ATGGACAACA TCAAGTACGG GGACAACACT 
AAAGAGATCT CCGTGGAGAG AGCCATAGCT GCTGCAAAGC AGGCTCAGCT GCATGACTTC 
GTCATGTCGC TCCCAGAGAA ATATGAAACT AATGTTGGGA TCCAGGGCTC TCAGCTCTCT 
CGTGGAGAGA AACAACGCAT TGCTATTGCT CGGGCCATTG TGCGAGATCC TAAAATCTTA 
CTACTGGATG AAGCTACGTC TGCCCTAGAC ACAGAAAGTG AAAAGACAGT GCAGACTGCT 
CTGGACAAAG CCAGAGAGGG TCGGACCTGC ATTGTCATTG CTCATCGTTT GTCCACCATC 
CAGAACTCAG ATATCATTGC TGTCGTGTCA CAAGGAGTGG TGATTGAAAA AGGGACCCAT 
GAGAAACTGA TGGCCCAGAA GGGAGCCTAC TACAAGCTGG TCATCACTGG AGCCCCCATC 
AGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tsumura-Suzuki obese diabetic mice-derived hepatic tumors closely resemble human hepatocellular carcinomas in metabolism-related genes expression and bile acid accumulation.
Hepatology international12(3)254-261(2018 May)
Takahashi T,Deuschle U,Taira S,Nishida T,Fujimoto M,Hijikata T,Tsuneyama K

Diagnosis of cirrhosis in patients with chronic hepatitis C genotype 4: Role of ABCB11 genotype polymorphism and plasma bile acid levels.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology29(3)299-307(2018 05)
Besheer T,Arafa M,El-Maksoud MA,Elalfy H,Hasson A,Zalata K,Elkashef W,Elshahawy H,Raafat D,Elemshaty W,Elsayed E,Zaghloul H,Razek AA,El-Bendary M

Dysregulation of BSEP and MRP2 May Play an Important Role in Isoniazid-Induced Liver Injury via the SIRT1/FXR Pathway in Rats and HepG2 Cells.
Biological & pharmaceutical bulletin41(8)1211-1218(2018)
Qu X,Zhang Y,Zhang S,Zhai J,Gao H,Tao L,Song Y

Adenovirus-mediated human aquaporin-1 expression in hepatocytes improves lipopolysaccharide-induced cholestasis.
IUBMB life69(12)978-984(2017 12)
Marrone J,Danielli M,Gaspari CI,Marinelli RA

Influence of ABCB11 and HNF4α genes on daclatasvir plasma concentration: preliminary pharmacogenetic data from the Kineti-C study.
The Journal of antimicrobial chemotherapy72(10)2846-2849(2017 10)
Cusato J,De Nicolò A,Boglione L,Favata F,Ariaudo A,Mornese Pinna S,Guido F,Avataneo V,Carcieri C,Cariti G,Di Perri G,D'Avolio A

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Abcb11 cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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