Gna11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gna11
Entrez Gene ID	81662
Full Name	G protein subunit alpha 11
General protein information	Preferred Names G protein subunit alpha 11 Names guanine nucleotide-binding protein subunit alpha-11 g alpha-11 guanine nucleotide binding protein, alpha 11 guanine nucleotide regulatory protein G alpha 11 guanine nucleotide-binding protein alpha 11 subunit
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q11
Summary	may be involved in mediating second messenger signals from the endothelin receptor in adipocytes [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031033.1	NP_112295.1	guanine nucleotide-binding protein subunit alpha-11

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Gna11	NP_034431.1
Danio rerio (zebrafish)	gna11b	NP_001007774.1
Caenorhabditis elegans (roundworm)	egl-30	NP_740789.1
Xenopus tropicalis (tropical clawed frog)	gna11	NP_989150.1
Macaca mulatta (Rhesus monkey)	GNA11	XP_001117841.2
Bos taurus (cattle)	GNA11	NP_776747.1
Pan troglodytes (chimpanzee)	GNA11	XP_003954570.1
Homo sapiens (human)	GNA11	NP_002058.2
Rattus norvegicus (Norway rat)	Gna11	NP_112295.1
Gallus gallus (chicken)	GNA11	NP_989565.1

Gene Ontology
Bibliography

Related articles in PubMed

Molecular properties of muscarinic acetylcholine receptors.
Haga T
Proceedings of the Japan Academy. Series B, Physical and biological sciences89(6)226-56(2013)

Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Gα(q/11)--p63RhoGEF--RhoA axis.
Siegert P, Schmidt G, Papatheodorou P, Wieland T, Aktories K, Orth JH
PLoS pathogens9(5)e1003385(2013)

Deficiency of proton-sensing ovarian cancer G protein-coupled receptor 1 attenuates glucose-stimulated insulin secretion.
Nakakura T, Mogi C, Tobo M, Tomura H, Sato K, Kobayashi M, Ohnishi H, Tanaka S, Wayama M, Sugiyama T, Kitamura T, Harada A, Okajima F
Endocrinology153(9)4171-80(2012 Sep)

The heterotrimeric G protein subunits Gα(q) and Gβ(1) have lysophospholipase D activity.
Aoyama C, Sugimoto H, Ando H, Yamashita S, Horibata Y, Sugimoto S, Satou M
The Biochemical journal440(2)241-50(2011 Dec)

The G-protein on cholesterol-rich membrane microdomains mediates mucosal sensing of short- chain fatty acid and secretory response in rat colon.
Yajima T, Inoue R, Yajima M, Tsuruta T, Karaki S, Hira T, Kuwahara A
Acta physiologica (Oxford, England)203(3)381-9(2011 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Gna11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gna11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07430	NM_031033.1 Latest version!	Rattus norvegicus G protein subunit alpha 11 (Gna11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gna11 ( NM_031033.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112295.1 Rattus norvegicus G protein subunit alpha 11 (Gna11), mRNA.

Price & Availability↑

CloneID	ORa07430
Clone ID Related Accession (Same CDS sequence)	NM_031033.1
Accession Version	NM_031033.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Rattus norvegicus(Norway rat)
Product	guanine nucleotide-binding protein subunit alpha-11
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF239674.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF239674.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGACTCTGG AGTCCATGAT AGCGTGTTGC CTGAGCGACG AGGTGAAGGA GTCGAAGCGC 
ATCAACGCGG AGATCGAGAA ACAGCTGCGG CGAGACAAGC GCGACGCCCG GCGCGAGCTC 
AAGCTGCTGC TTCTCGGCAC TGGCGAGAGC GGGAAGAGCA CCTTCATCAA GCAGATGCGC 
ATCATCCATG GCGCCGGCTA CTCGGAGGAG GACAAACGCG GCTTCACAAA GCTGGTGTAC 
CAGAACATCT TCACCGCCAT GCAGGCTGTG GTGCGCGCTA TGGACACGCT CAAGATCCGC 
TACAAGTATG AGCAGAACAA GGCCAATGCA CTCCTGATCC GGGAGGTTGA TGTGGAGAAG 
GTCACGACTT TTGAGCATCA GTATGTGAAC GCCATCAAGA CACTGTGGAG TGACCCTGGT 
GTCCAGGAGT GCTACGATCG CAGGCGAGAG TTCCAGCTCT CTGACTCGGC TAAGTACTAC 
TTGACGGACG TGGACCGCAT CGCTACAGTA GGCTACCTGC CCACCCAGCA GGATGTGCTG 
CGGGTACGTG TGCCCACAAC TGGCATCATC GAGTACCCGT TTGACCTGGA GAACATCATC 
TTCAGGATGG TGGATGTGGG CGGGCAGAGG TCAGAGCGCA GGAAGTGGAT CCATTGCTTT 
GAGAATGTCA CGTCCATCAT GTTCTTGGTG GCATTAAGCG AGTATGACCA GGTCCTGGTG 
GAGTCGGACA ACGAGAACCG CATGGAGGAG AGCAAGGCCC TGTTCCGCAC AATCATCACC 
TACCCCTGGT TCCAGCACTC GTCTGTGATC CTCTTCCTCA ACAAGAAGGA CCTTCTGGAA 
GACAAGATCC TGCACTCACA CTTGGTCGAC TACTTCCCCG AGTTCGATGG GCCACAGAGG 
GACGCACAGG CCGCCCGCGA GTTCATCCTG AAGATGTTTG TGGATCTGAA CCCCGACAGC 
GACAAGATCA TCTACTCGCA CTTCACCTGC GCCACGGACA CCGAAAACAT CCGCTTCGTG 
TTTGCTGCCG TGAAGGACAC CATCCTGCAG CTGAACCTGA AGGAGTACAA CCTGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112295.1
CDS	1..1080
Translation	MTLESMIACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAVVRAMDTLKIRYKYEQNKANALLIREVDVEKVTTFEHQYVNAIKTLWSDPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQHSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV

Target ORF information:

RefSeq Version	NM_031033.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein subunit alpha 11 (Gna11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031033.1

ORF Insert Sequence:

ATGACTCTGG AGTCCATGAT AGCGTGTTGC CTGAGCGACG AGGTGAAGGA GTCGAAGCGC 
ATCAACGCGG AGATCGAGAA ACAGCTGCGG CGAGACAAGC GCGACGCCCG GCGCGAGCTC 
AAGCTGCTGC TTCTCGGCAC TGGCGAGAGC GGGAAGAGCA CCTTCATCAA GCAGATGCGC 
ATCATCCATG GCGCCGGCTA CTCGGAGGAG GACAAACGCG GCTTCACAAA GCTGGTGTAC 
CAGAACATCT TCACCGCCAT GCAGGCTGTG GTGCGCGCTA TGGACACGCT CAAGATCCGC 
TACAAGTATG AGCAGAACAA GGCCAATGCA CTCCTGATCC GGGAGGTTGA TGTGGAGAAG 
GTCACGACTT TTGAGCATCA GTATGTGAAC GCCATCAAGA CACTGTGGAG TGACCCTGGT 
GTCCAGGAGT GCTACGATCG CAGGCGAGAG TTCCAGCTCT CTGACTCGGC TAAGTACTAC 
TTGACGGACG TGGACCGCAT CGCTACAGTA GGCTACCTGC CCACCCAGCA GGATGTGCTG 
CGGGTACGTG TGCCCACAAC TGGCATCATC GAGTACCCGT TTGACCTGGA GAACATCATC 
TTCAGGATGG TGGATGTGGG CGGGCAGAGG TCAGAGCGCA GGAAGTGGAT CCATTGCTTT 
GAGAATGTCA CGTCCATCAT GTTCTTGGTG GCATTAAGCG AGTATGACCA GGTCCTGGTG 
GAGTCGGACA ACGAGAACCG CATGGAGGAG AGCAAGGCCC TGTTCCGCAC AATCATCACC 
TACCCCTGGT TCCAGCACTC GTCTGTGATC CTCTTCCTCA ACAAGAAGGA CCTTCTGGAA 
GACAAGATCC TGCACTCACA CTTGGTCGAC TACTTCCCCG AGTTCGATGG GCCACAGAGG 
GACGCACAGG CCGCCCGCGA GTTCATCCTG AAGATGTTTG TGGATCTGAA CCCCGACAGC 
GACAAGATCA TCTACTCGCA CTTCACCTGC GCCACGGACA CCGAAAACAT CCGCTTCGTG 
TTTGCTGCCG TGAAGGACAC CATCCTGCAG CTGAACCTGA AGGAGTACAA CCTGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Molecular properties of muscarinic acetylcholine receptors.
Proceedings of the Japan Academy. Series B, Physical and biological sciences89(6)226-56(2013)
Haga T

Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Gα(q/11)--p63RhoGEF--RhoA axis.
PLoS pathogens9(5)e1003385(2013)
Siegert P,Schmidt G,Papatheodorou P,Wieland T,Aktories K,Orth JH

Deficiency of proton-sensing ovarian cancer G protein-coupled receptor 1 attenuates glucose-stimulated insulin secretion.
Endocrinology153(9)4171-80(2012 Sep)
Nakakura T,Mogi C,Tobo M,Tomura H,Sato K,Kobayashi M,Ohnishi H,Tanaka S,Wayama M,Sugiyama T,Kitamura T,Harada A,Okajima F

The heterotrimeric G protein subunits Gα(q) and Gβ(1) have lysophospholipase D activity.
The Biochemical journal440(2)241-50(2011 Dec)
Aoyama C,Sugimoto H,Ando H,Yamashita S,Horibata Y,Sugimoto S,Satou M

The G-protein on cholesterol-rich membrane microdomains mediates mucosal sensing of short- chain fatty acid and secretory response in rat colon.
Acta physiologica (Oxford, England)203(3)381-9(2011 Nov)
Yajima T,Inoue R,Yajima M,Tsuruta T,Karaki S,Hira T,Kuwahara A

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Gna11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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