Serp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Serp1
Entrez Gene ID	80881
Full Name	stress-associated endoplasmic reticulum protein 1
Synonyms	RAMP4
General protein information	Preferred Names stress-associated endoplasmic reticulum protein 1 Names stress-associated endoplasmic reticulum protein 1 ribosome associated membrane protein 4 ribosome-attached membrane protein 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q26
Summary	may be involved in glycosylation modification of secretory and membrane proteins including glycosylation of MHC class II-associated invariant chain (li) [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_030835.2	NP_110462.1	stress-associated endoplasmic reticulum protein 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SERP1	NP_001107555.1
Danio rerio (zebrafish)	zgc:92744	NP_001002573.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001548	XP_003435867.1
Rattus norvegicus (Norway rat)	Serp1	NP_110462.1
Drosophila melanogaster (fruit fly)	CG32276	NP_728831.1
Homo sapiens (human)	SERP1	NP_055260.1
Pan troglodytes (chimpanzee)	SERP1	XP_003950262.1
Xenopus tropicalis (tropical clawed frog)	serp1	NP_989085.1
Mus musculus (house mouse)	Serp1	NP_109610.1

Gene Ontology
Bibliography

Related articles in PubMed

MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis.
Fong KW, Leung JW, Li Y, Wang W, Feng L, Ma W, Liu D, Songyang Z, Chen J
Journal of cell science126(Pt 3)825-37(2013 Feb)

Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress.
Hori O, Miyazaki M, Tamatani T, Ozawa K, Takano K, Okabe M, Ikawa M, Hartmann E, Mai P, Stern DM, Kitao Y, Ogawa S
Molecular and cellular biology26(11)4257-67(2006 Jun)

Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis.
Matsuki T, Nakae S, Sudo K, Horai R, Iwakura Y
International immunology18(2)399-407(2006 Feb)

Stress-associated endoplasmic reticulum protein 1 (SERP1)/Ribosome-associated membrane protein 4 (RAMP4) stabilizes membrane proteins during stress and facilitates subsequent glycosylation.
Yamaguchi A, Hori O, Stern DM, Hartmann E, Ogawa S, Tohyama M
The Journal of cell biology147(6)1195-204(1999 Dec)

Control of glycosylation of MHC class II-associated invariant chain by translocon-associated RAMP4.
Schröder K, Martoglio B, Hofmann M, Hölscher C, Hartmann E, Prehn S, Rapoport TA, Dobberstein B
The EMBO journal18(17)4804-15(1999 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Serp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Serp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07136	NM_030835.2 Latest version!	Rattus norvegicus stress-associated endoplasmic reticulum protein 1 (Serp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Serp1 ( NM_030835.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_110462.1 Rattus norvegicus stress-associated endoplasmic reticulum protein 1 (Serp1), mRNA.

Price & Availability↑

CloneID	ORa07136
Clone ID Related Accession (Same CDS sequence)	NM_030835.2
Accession Version	NM_030835.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 201bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1536854400000
Organism	Rattus norvegicus(Norway rat)
Product	stress-associated endoplasmic reticulum protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC061854.1. On Feb 9, 2004 this sequence version replaced NM_030835.1. ##Evidence-Data-START## Transcript exon combination :: BC061854.1, AB018546.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348, SAMN01906349 [ECO:0000348] ##Evidence-Data-END##

ATGGTCGCCA AGCAGAGGAT CCGTATGGCC AACGAGAAGC ACAGCAAGAA CATAACTCAG 
CGCGGCAACG TCGCTAAGAC CTCGAGAAAT GCCCCCGAAG AAAAGGCGTC GGTAGGACCC 
TGGTTATTGG CCCTCTTCAT TTTTGTCGTT TGTGGATCTG CAATTTTCCA GATTATTCAA 
AGTATCAGGA TGGGCATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_110462.1
CDS	368..568
Translation	MVAKQRIRMANEKHSKNITQRGNVAKTSRNAPEEKASVGPWLLALFIFVVCGSAIFQIIQSIRMGM

Target ORF information:

RefSeq Version	NM_030835.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus stress-associated endoplasmic reticulum protein 1 (Serp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030835.2

ORF Insert Sequence:

ATGGTCGCCA AGCAGAGGAT CCGTATGGCC AACGAGAAGC ACAGCAAGAA CATAACTCAG 
CGCGGCAACG TCGCTAAGAC CTCGAGAAAT GCCCCCGAAG AAAAGGCGTC GGTAGGACCC 
TGGTTATTGG CCCTCTTCAT TTTTGTCGTT TGTGGATCTG CAATTTTCCA GATTATTCAA 
AGTATCAGGA TGGGCATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis.
Journal of cell science126(Pt 3)825-37(2013 Feb)
Fong KW,Leung JW,Li Y,Wang W,Feng L,Ma W,Liu D,Songyang Z,Chen J

Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress.
Molecular and cellular biology26(11)4257-67(2006 Jun)
Hori O,Miyazaki M,Tamatani T,Ozawa K,Takano K,Okabe M,Ikawa M,Hartmann E,Mai P,Stern DM,Kitao Y,Ogawa S

Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis.
International immunology18(2)399-407(2006 Feb)
Matsuki T,Nakae S,Sudo K,Horai R,Iwakura Y

Stress-associated endoplasmic reticulum protein 1 (SERP1)/Ribosome-associated membrane protein 4 (RAMP4) stabilizes membrane proteins during stress and facilitates subsequent glycosylation.
The Journal of cell biology147(6)1195-204(1999 Dec)
Yamaguchi A,Hori O,Stern DM,Hartmann E,Ogawa S,Tohyama M

Control of glycosylation of MHC class II-associated invariant chain by translocon-associated RAMP4.
The EMBO journal18(17)4804-15(1999 Sep)
Schröder K,Martoglio B,Hofmann M,Hölscher C,Hartmann E,Prehn S,Rapoport TA,Dobberstein B

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Serp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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