| Gene Symbol | Dnal1 |
| Entrez Gene ID | 685664 |
| Full Name | dynein, axonemal, light chain 1 |
| Synonyms | Dnalc1,LC1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
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Dnal1 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Dnal1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dnal1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa10055 Clone ID Related Accession (Same CDS sequence) NM_001109477.2 Accession Version NM_001109477.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 573bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1550332800000 Organism Rattus norvegicus(Norway rat) Product dynein light chain 1, axonemal Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EV765393.1 and BF394767.1. On Jan 11, 2008 this sequence version replaced NM_001109477.1. ##Evidence-Data-START## Transcript exon combination :: FQ211665.1, FM089520.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##
1
61
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481
541ATGGCAAAAG CAACAACAAT CAAAGAAGCC CTGTCCAGAT GGGAAGAAAA GACCGGTCAG
AAGCCATCTG ATGCCAGAGA AATAAAGCTG TATGCCCAGA TCCCCCCCAT AGAGAAGATG
GACGCGTCTC TGTCCACACT TGCTAACTGC GAGAAGCTTT CCCTGTCTAC AAACTGCATT
GAAAAAATTG CCAACCTGAA TGGCCTAAAA AACTTGAGGA TTCTGTCCTT AGGAAGAAAC
AACATCAAGA ACCTAAATGG ACTGGAAGCA GTCGGAGACA CACTAGAAGA ACTGTGGATC
TCCTACAATT TTATTGAGAA GTTGAAAGGG ATCCATGTAA TGAGGAAACT GAAGATTCTC
TACATATCTA ATAACCTGGT AAAAGACTGG GCTGAGTTTG TGAAGCTGGC TGAGCTGCCG
TGCCTGGAGG ACCTGGTATT TGTGGGCAAT CCCCTGGAGG AGAAGCATTC TGCTGAGGGC
AACTGGATTG AAGAAGCTAC CAAGAGGGTG CCCAAGCTGA AGAAGCTGGA TGGTACTCCA
GTAATTAAGG AGGATGAAGA AGAGGAAAGC TAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001102947.2 CDS 8..580 Translation 
Target ORF information:
RefSeq Version NM_001109477.2 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus dynein, axonemal, light chain 1 (Dnal1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001109477.2
ORF Insert Sequence:
1
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121
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421
481
541ATGGCAAAAG CAACAACAAT CAAAGAAGCC CTGTCCAGAT GGGAAGAAAA GACCGGTCAG
AAGCCATCTG ATGCCAGAGA AATAAAGCTG TATGCCCAGA TCCCCCCCAT AGAGAAGATG
GACGCGTCTC TGTCCACACT TGCTAACTGC GAGAAGCTTT CCCTGTCTAC AAACTGCATT
GAAAAAATTG CCAACCTGAA TGGCCTAAAA AACTTGAGGA TTCTGTCCTT AGGAAGAAAC
AACATCAAGA ACCTAAATGG ACTGGAAGCA GTCGGAGACA CACTAGAAGA ACTGTGGATC
TCCTACAATT TTATTGAGAA GTTGAAAGGG ATCCATGTAA TGAGGAAACT GAAGATTCTC
TACATATCTA ATAACCTGGT AAAAGACTGG GCTGAGTTTG TGAAGCTGGC TGAGCTGCCG
TGCCTGGAGG ACCTGGTATT TGTGGGCAAT CCCCTGGAGG AGAAGCATTC TGCTGAGGGC
AACTGGATTG AAGAAGCTAC CAAGAGGGTG CCCAAGCTGA AGAAGCTGGA TGGTACTCCA
GTAATTAAGG AGGATGAAGA AGAGGAAAGC TAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID ORa29490 Clone ID Related Accession (Same CDS sequence) XM_006240352.3 Accession Version XM_006240352.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 750bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1469376000000 Organism Rattus norvegicus(Norway rat) Product dynein light chain 1, axonemal isoform X1 Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240352.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##
1
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121
181
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541
601
661
721ATGTTAAGTT CTAGGAAGGC AGGAATCTGT TTCATACATT ATGTGTCCGA ATCAAATAGA
AAACCAGACA TGATGGTGCA CACCTGTCAT CTCGGGACTC AGAAAAAAAA ATATGACATA
GAAGAATGCA AGTCACACAG TAGACATACA GTGAACAGCT GTGGAACTGA GTTCCCTGAG
GCAAAAGCAA CAACAATCAA AGAAGCCCTG TCCAGATGGG AAGAAAAGAC CGGTCAGAAG
CCATCTGATG CCAGAGAAAT AAAGCTGTAT GCCCAGATCC CCCCCATAGA GAAGATGGAC
GCGTCTCTGT CCACACTTGC TAACTGCGAG AAGCTTTCCC TGTCTACAAA CTGCATTGAA
AAAATTGCCA ACCTGAATGG CCTAAAAAAC TTGAGGATTC TGTCCTTAGG AAGAAACAAC
ATCAAGAACC TAAATGGACT GGAAGCAGTC GGAGACACAC TAGAAGAACT GTGGATCTCC
TACAATTTTA TTGAGAAGTT GAAAGGGATC CATGTAATGA GGAAACTGAA GATTCTCTAC
ATATCTAATA ACCTGGTAAA AGACTGGGCT GAGTTTGTGA AGCTGGCTGA GCTGCCGTGC
CTGGAGGACC TGGTATTTGT GGGCAATCCC CTGGAGGAGA AGCATTCTGC TGAGGGCAAC
TGGATTGAAG AAGCTACCAA GAGGGTGCCC AAGCTGAAGA AGCTGGATGG TACTCCAGTA
ATTAAGGAGG ATGAAGAAGA GGAAAGCTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq XP_006240414.1 CDS 39..788 Translation
Target ORF information:
RefSeq Version XM_006240352.3 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus dynein, axonemal, light chain 1 (Dnal1), transcript variant X1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK XM_006240352.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721ATGTTAAGTT CTAGGAAGGC AGGAATCTGT TTCATACATT ATGTGTCCGA ATCAAATAGA
AAACCAGACA TGATGGTGCA CACCTGTCAT CTCGGGACTC AGAAAAAAAA ATATGACATA
GAAGAATGCA AGTCACACAG TAGACATACA GTGAACAGCT GTGGAACTGA GTTCCCTGAG
GCAAAAGCAA CAACAATCAA AGAAGCCCTG TCCAGATGGG AAGAAAAGAC CGGTCAGAAG
CCATCTGATG CCAGAGAAAT AAAGCTGTAT GCCCAGATCC CCCCCATAGA GAAGATGGAC
GCGTCTCTGT CCACACTTGC TAACTGCGAG AAGCTTTCCC TGTCTACAAA CTGCATTGAA
AAAATTGCCA ACCTGAATGG CCTAAAAAAC TTGAGGATTC TGTCCTTAGG AAGAAACAAC
ATCAAGAACC TAAATGGACT GGAAGCAGTC GGAGACACAC TAGAAGAACT GTGGATCTCC
TACAATTTTA TTGAGAAGTT GAAAGGGATC CATGTAATGA GGAAACTGAA GATTCTCTAC
ATATCTAATA ACCTGGTAAA AGACTGGGCT GAGTTTGTGA AGCTGGCTGA GCTGCCGTGC
CTGGAGGACC TGGTATTTGT GGGCAATCCC CTGGAGGAGA AGCATTCTGC TGAGGGCAAC
TGGATTGAAG AAGCTACCAA GAGGGTGCCC AAGCTGAAGA AGCTGGATGG TACTCCAGTA
ATTAAGGAGG ATGAAGAAGA GGAAAGCTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Primary ciliary dyskinesia caused by homozygous mutation in DNAL1, encoding dynein light chain 1.
American journal of human genetics88(5)599-607(2011 May)
Mazor M,Alkrinawi S,Chalifa-Caspi V,Manor E,Sheffield VC,Aviram M,Parvari R
Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.
American journal of respiratory cell and molecular biology33(1)41-7(2005 Jul)
Horváth J,Fliegauf M,Olbrich H,Kispert A,King SM,Mitchison H,Zariwala MA,Knowles MR,Sudbrak R,Fekete G,Neesen J,Reinhardt R,Omran H
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