dnal1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	dnal1
Entrez Gene ID	445048
Full Name	dynein, axonemal, light chain 1
Synonyms	wu:fc89a04,zgc:92542
General protein information	Preferred Names dynein, axonemal, light chain 1 Names dynein light chain 1, axonemal fc89a04
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003442.1	NP_001003442.1	dynein light chain 1, axonemal

Pathways from BioSystems

Homologies

Homo sapiens (human)	DNAL1	NP_113615.2
Rattus norvegicus (Norway rat)	Dnal1	NP_001102947.2
Xenopus tropicalis (tropical clawed frog)	dnal1	NP_001016312.1
Pan troglodytes (chimpanzee)	DNAL1	XP_001141594.1
Mus musculus (house mouse)	Dnal1	NP_083097.2
Gallus gallus (chicken)	DNAL1	NP_001186610.1
Danio rerio (zebrafish)	dnal1	NP_001003442.1
Drosophila melanogaster (fruit fly)	CG8800	NP_610483.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004416	XP_313700.4
Macaca mulatta (Rhesus monkey)	DNAL1	XP_001085992.1
Canis lupus familiaris (dog)	DNAL1	XP_853805.1
Bos taurus (cattle)	DNAL1	NP_001039892.1

Gene Ontology
Bibliography

Related articles in PubMed

Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of
Tavares B, Jacinto R, Sampaio P, Pestana S, Pinto A, Vaz A, Roxo-Rosa M, Gardner R, Lopes T, Schilling B, Henry I, Saúde L, Lopes SS
eLife6(2017 09)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility.
Zhao L, Yuan S, Cao Y, Kallakuri S, Li Y, Kishimoto N, DiBella L, Sun Z
Proceedings of the National Academy of Sciences of the United States of America110(31)12697-702(2013 Jul)

Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.
Horváth J, Fliegauf M, Olbrich H, Kispert A, King SM, Mitchison H, Zariwala MA, Knowles MR, Sudbrak R, Fekete G, Neesen J, Reinhardt R, Omran H
American journal of respiratory cell and molecular biology33(1)41-7(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following dnal1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the dnal1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01279	NM_001003442.1 Latest version!	Danio rerio dynein, axonemal, light chain 1 (dnal1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

dnal1 ( NM_001003442.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001003442.1 Danio rerio dynein, axonemal, light chain 1 (dnal1), mRNA.

Price & Availability↑

CloneID	ODa01279
Clone ID Related Accession (Same CDS sequence)	NM_001003442.1
Accession Version	NM_001003442.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1542902400000
Organism	Danio rerio(zebrafish)
Product	dynein light chain 1, axonemal
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC076064.1. ##Evidence-Data-START## Transcript exon combination :: BC076064.1, CK025242.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGCAAAAG CAACAACTAT TAAAGAGGCC CTGGTGAAAT GGGAGGAAAA AACTGGTGAA 
AAAGCAAATG ATGCCACGGC AGTAAAGCTT TATGGTCAAA TCCCTCCCAT TGAAAAAATG 
GATGCATCTC TCTCTAATCT TGTCAACTGC GAGAGATTGT CCTTGTCTAC AAACTGCATT 
GAAAAAATTG CCAACTTAAA TGGTCTAAAA AACCTTAAGA TATTGTCCTT GGGGCGGAAT 
AACATCAAAA ACCTCAATGG ACTCGAGGCA GTGGGTGATA CTCTGGAGGA GCTGTGGATC 
TCTTATAACC TCATAGAAAA ACTGAAGGGA ATTCATGTCA TGAAGAAACT TAAAGTCTTA 
TACATGTCCA ACAACTTGGT GAAGGAGTGG GGGGAGTTTC TGAAACTGGC AGATCTTCCA 
TCACTGGTTG ACCTTGTCTT TGTGGGAAAC CCATTAGAAG AAAAATATTC TGCAGATGGC 
AACTGGATAG AGGAGGCTAC AAAGAGACTT CCCAAACTCA AAAAGCTAGA TGGGAATCCT 
GTCATCAAAC AAGAGGAGGA AACTGAAGGG GAGAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003442.1
CDS	5..583
Translation	MAKATTIKEALVKWEEKTGEKANDATAVKLYGQIPPIEKMDASLSNLVNCERLSLSTNCIEKIANLNGLKNLKILSLGRNNIKNLNGLEAVGDTLEELWISYNLIEKLKGIHVMKKLKVLYMSNNLVKEWGEFLKLADLPSLVDLVFVGNPLEEKYSADGNWIEEATKRLPKLKKLDGNPVIKQEEETEGES

Target ORF information:

RefSeq Version	NM_001003442.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio dynein, axonemal, light chain 1 (dnal1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003442.1

ORF Insert Sequence:

ATGGCAAAAG CAACAACTAT TAAAGAGGCC CTGGTGAAAT GGGAGGAAAA AACTGGTGAA 
AAAGCAAATG ATGCCACGGC AGTAAAGCTT TATGGTCAAA TCCCTCCCAT TGAAAAAATG 
GATGCATCTC TCTCTAATCT TGTCAACTGC GAGAGATTGT CCTTGTCTAC AAACTGCATT 
GAAAAAATTG CCAACTTAAA TGGTCTAAAA AACCTTAAGA TATTGTCCTT GGGGCGGAAT 
AACATCAAAA ACCTCAATGG ACTCGAGGCA GTGGGTGATA CTCTGGAGGA GCTGTGGATC 
TCTTATAACC TCATAGAAAA ACTGAAGGGA ATTCATGTCA TGAAGAAACT TAAAGTCTTA 
TACATGTCCA ACAACTTGGT GAAGGAGTGG GGGGAGTTTC TGAAACTGGC AGATCTTCCA 
TCACTGGTTG ACCTTGTCTT TGTGGGAAAC CCATTAGAAG AAAAATATTC TGCAGATGGC 
AACTGGATAG AGGAGGCTAC AAAGAGACTT CCCAAACTCA AAAAGCTAGA TGGGAATCCT 
GTCATCAAAC AAGAGGAGGA AACTGAAGGG GAGAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of
eLife6(2017 09)
Tavares B,Jacinto R,Sampaio P,Pestana S,Pinto A,Vaz A,Roxo-Rosa M,Gardner R,Lopes T,Schilling B,Henry I,Saúde L,Lopes SS

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility.
Proceedings of the National Academy of Sciences of the United States of America110(31)12697-702(2013 Jul)
Zhao L,Yuan S,Cao Y,Kallakuri S,Li Y,Kishimoto N,DiBella L,Sun Z

Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.
American journal of respiratory cell and molecular biology33(1)41-7(2005 Jul)
Horváth J,Fliegauf M,Olbrich H,Kispert A,King SM,Mitchison H,Zariwala MA,Knowles MR,Sudbrak R,Fekete G,Neesen J,Reinhardt R,Omran H

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dnal1 cDNA ORF clone, Danio rerio(zebrafish)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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