Myo1c cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Myo1c
Entrez Gene ID	65261
Full Name	myosin 1C
Synonyms	Myr2
General protein information	Preferred Names myosin 1C Names unconventional myosin-Ic MMI-beta MMIb myosin I beta myosin IC myosin IC-like myosin heavy chain myr 2 myosin-Ic unconventional myosin Myr2 I heavy chain
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q24
Summary	novel class-I Myosin found in brain [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_023092.1	NP_075580.2	unconventional myosin-Ic

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MYO1C	XP_001174155.2
Bos taurus (cattle)	MYO1C	NP_776821.3
Mus musculus (house mouse)	Myo1c	NP_001074244.1
Gallus gallus (chicken)	MYO1C	NP_001006220.2
Danio rerio (zebrafish)	myo1c	XP_694821.5
Canis lupus familiaris (dog)	MYO1C	XP_003639307.1
Xenopus tropicalis (tropical clawed frog)	myo1c	XP_002942189.2
Rattus norvegicus (Norway rat)	Myo1c	NP_075580.2
Drosophila melanogaster (fruit fly)	Myo61F	NP_728594.2
Homo sapiens (human)	MYO1C	NP_001074248.1

Gene Ontology
Bibliography

Related articles in PubMed

The role of myosin 1c and myosin 1b in surfactant exocytosis.
Kittelberger N, Breunig M, Martin R, Knölker HJ, Miklavc P
Journal of cell science129(8)1685-96(2016 Apr)

Rho GTPases in insulin-stimulated glucose uptake.
Satoh T
Small GTPases5e28102(2014)

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.
Simicek M, Lievens S, Laga M, Guzenko D, Aushev VN, Kalev P, Baietti MF, Strelkov SV, Gevaert K, Tavernier J, Sablina AA
Nature cell biology15(10)1220-30(2013 Oct)

The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling.
Tiwari A, Jung JJ, Inamdar SM, Nihalani D, Choudhury A
American journal of physiology. Heart and circulatory physiology304(5)H687-96(2013 Mar)

Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles.
Boguslavsky S, Chiu T, Foley KP, Osorio-Fuentealba C, Antonescu CN, Bayer KU, Bilan PJ, Klip A
Molecular biology of the cell23(20)4065-78(2012 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Myo1c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Myo1c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06581	NM_023092.1 Latest version!	Rattus norvegicus myosin 1C (Myo1c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Myo1c ( NM_023092.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_075580.2 Rattus norvegicus myosin 1C (Myo1c), mRNA.

Price & Availability↑

CloneID	ORa06581
Clone ID Related Accession (Same CDS sequence)	NM_023092.1
Accession Version	NM_023092.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3135bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Rattus norvegicus(Norway rat)
Product	unconventional myosin-Ic
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X74800.1. On Jun 25, 2006 this sequence version replaced XM_001080717.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X74800.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCGCTACC GGGCGTCGGC CCTGGGCAGT GACGGGGTAC GAGTGACCAT GGAGAGCGCC 
TTGACTGCCC GAGACCGGGT GGGGGTGCAA GACTTTGTTC TGCTGGAGAA CTTCACCAGT 
GAGGCTGCCT TCATTGAGAA CCTCCGGCGT CGATTCCGGG AGAACCTCAT TTATACCTAC 
ATTGGCCCTG TCCTGGTCTC TGTCAACCCC TACCGGGACC TACAGATCTA CACACGGCAA 
CATATGGAAC GCTACCGTGG CGTCAGTTTC TATGAAGTGC CGCCTCATCT GTTTGCAGTG 
GCTGACACTG TATACCGGGC GCTTCGTACT GAGCGTCGGG ACCAAGCAGT GATGATTTCT 
GGAGAGAGTG GGGCAGGGAA GACAGAGGCC ACCAAGAGAT TGCTCCAGTT CTATGCAGAG 
ACCTGCCCAG CCCCTGAAAG GGGTGGCGCA GTGCGAGACC GCCTGTTGCA GAGCAACCCT 
GTGCTGGAGG CCTTTGGGAA TGCCAAGACT CTCCGCAACG ACAACTCCAG CCGCTTTGGG 
AAGTACATGG ATGTGCAGTT TGACTTCAAG GGTGCCCCTG TGGGAGGCCA CATTCTCAGT 
TACCTCCTGG AGAAGTCTCG AGTGGTACAC CAGAATCACG GAGAACGGAA CTTCCACGTC 
TTTTACCAGC TCCTGGAGGG GGGGGAGGAG GAGGCTCTTC GTCGTCTGGG CTTGGAACGG 
AACCCCCAGA GCTACTTGTA CCTGGTGAAG GGCCAGTGTG CCAAGGTCTC CTCCATCAAT 
GACAAGAGTG ACTGGAAGGT TGTGAGGAAG GCGCTGTCAG TCATTGACTT CACTGAGGAT 
GAAGTGGAGG ACTTGCTAAG CATCGTGGCC AGCGTCCTAC ATCTGGGCAA TATCCACTTT 
GCTGCTGATG AGGACAGCAA TGCCCAGGTT ACTACTGAGA ACCAGCTCAA ATATCTGACC 
AGGCTCCTTG GTGTGGAAGG CACAACACTG AGGGAAGCCC TGACCCACAG GAAGATCATC 
GCCAAGGGGG AAGAGCTCCT GAGCCCACTG AACCTTGAAC AGGCTGCATA TGCAAGGGAT 
GCTCTTGCCA AGGCTGTGTA CAGCCGCACT TTCACCTGGT TGGTCAGAAA GATCAATAGG 
TCTCTGGCCT CTAAGGACGC TGAGAGCCCC AGCTGGCGAA GCACCACAGT TCTTGGGCTC 
CTGGACATTT ATGGCTTCGA AGTGTTTCAG CATAACAGCT TCGAGCAGTT CTGCATCAAC 
TATTGCAATG AGAAGCTGCA GCAGCTCTTC ATTGAGCTGA CTCTCAAGTC CGAGCAGGAG 
GAATACGAGG CAGAGGGCAT CGCGTGGGAA CCTGTCCAAT ACTTCAACAA CAAGATCATC 
TGTGACCTGG TGGAGGAGAA ATTCAAGGGC ATCATCTCCA TCTTGGATGA AGAGTGCCTG 
CGTCCTGGGG AGGCCACAGA CCTGACCTTC CTGGAGAAGC TGGAGGACAC AATCAAGCAC 
CACCCTCACT TCCTGACGCA CAAGCTTGCT GACCAGAAGA CCAGGAAATC CCTCGACCGA 
GGGGAGTTCC GCCTTCTTCA TTATGCGGGA GAGGTGACCT ACAGCGTGAC TGGGTTTCTG 
GATAAAAACA ATGACCTCCT CTTCCGGAAC CTGAAGGAGA CCATGTGCAG CTCCACGAAC 
CCCATCATGG CCCAGTGCTT TGACAAGAGT GAGCTCAGTG ACAAGAAGCG GCCAGAGACG 
GTGGCCACCC AGTTCAAGAT GAGCCTCTTG CAGCTAGTGG AGATCCTGAG GTCTAAGGAA 
CCTGCTTATA TCCGGTGCAT CAAGCCAAAT GACGCCAAAC AGCCGGGTCG CTTTGATGAG 
GTGCTCATCC GACACCAAGT GAAGTACCTG GGACTTATGG AGAATCTGCG TGTGCGCAGA 
GCTGGCTTTG CCTACCGTCG AAAATATGAG GCTTTCCTGC AGAGGTACAA GTCACTGTGC 
CCAGAGACAT GGCCCGTGTG GACAGGACGG CCCCAGGATG GGGTGGCTGT GTTGGTCAGA 
CACCTTGGCT ATAAGCCAGA AGAGTACAAA ATGGGCAGGA CTAAGATCTT CATCCGATTC 
CCCAAGACCT TGTTTGCCAC AGAGGACTCC CTGGAAGTCC GACGGCAGAG TCTAGCCACC 
AAGATCCAGG CGGCGTGGAG GGGCTTTCAT TGGCGGCAGA AATTTCTCCG GGTGAAGCGA 
TCAGCCATCT GTATCCAGTC CTGGTGGCGC GGTACACTGG GCCGGAGGAA GGCAGCCAAA 
AGGAAGTGGG CAGCCCAGAC TATCCGTAGA CTCATCCGTG GCTTCATTTT GCGTCATGCA 
CCCCGGTGCC CTGAGAATGC CTTCTTCCTG GACCACGTGC GCACGTCATT TTTGCTTAAC 
CTGAGGCGAC AACTACCCCG GAATGTTCTG GACACCTCCT GGCCCACACC CCCACCTGCC 
CTGAGAGAGG CCTCGGAGCT GCTCCGGGAG CTATGCATGA AGAACATGGT GTGGAAATAC 
TGCCGGAGTA TCAGCCCTGA GTGGAAGCAG CAGCTGCAGC AAAAGGCGGT GGCTAGTGAA 
ATTTTCAAGG GCAAGAAGGA CAATTACCCC CAGAGTGTCC CCAGACTTTT CATCAGCACA 
CGGCTTGGCA CAGAGGAGAT CAGCCCCAGA GTGCTTCAGG CCTTGGGCTC TGAACCCATC 
CAGTATGCAG TGCCTGTGGT AAAATACGAC CGTAAGGGCT ACAAGCCTCG TTCCCGGCAG 
CTGCTGCTCA CACCCAGTGC TGTGGTCATC GTGGAGGATG CCAAAGTCAA GCAGAGAATT 
GATTATGCCA ACCTAACTGG AATCTCCGTC AGTAGCCTGA GTGATAGCCT GTTTGTGCTT 
CACGTGCAGC GTGAAGACAG CAAGCAGAAG GGAGATGTGG TACTGCAGAG CGATCATGTG 
ATCGAGACAC TAACCAAGAC GGCCCTCAGT GCTGACCGTG TGAATAATAT CAACATCAAC 
CAGGGCAGCA TCACGTTTGC AGGGGGTCCA GGCAGGGATG GCATCATCGA CTTCACATCT 
GGCTCAGAGC TTCTCATCAC CAAGGCTAAG AATGGCCACC TGGCTGTGGT GGCCCCACGG 
CTGAATTCTC GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_075580.2
CDS	219..3353
Translation	MRYRASALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYTRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHVFYQLLEGGEEEALRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALSVIDFTEDEVEDLLSIVASVLHLGNIHFAADEDSNAQVTTENQLKYLTRLLGVEGTTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVRKINRSLASKDAESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTIKHHPHFLTHKLADQKTRKSLDRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSTNPIMAQCFDKSELSDKKRPETVATQFKMSLLQLVEILRSKEPAYIRCIKPNDAKQPGRFDEVLIRHQVKYLGLMENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPVWTGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDSLEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFILRHAPRCPENAFFLDHVRTSFLLNLRRQLPRNVLDTSWPTPPPALREASELLRELCMKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTEEISPRVLQALGSEPIQYAVPVVKYDRKGYKPRSRQLLLTPSAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQREDSKQKGDVVLQSDHVIETLTKTALSADRVNNININQGSITFAGGPGRDGIIDFTSGSELLITKAKNGHLAVVAPRLNSR

Target ORF information:

RefSeq Version	NM_023092.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus myosin 1C (Myo1c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023092.1

ORF Insert Sequence:

ATGCGCTACC GGGCGTCGGC CCTGGGCAGT GACGGGGTAC GAGTGACCAT GGAGAGCGCC 
TTGACTGCCC GAGACCGGGT GGGGGTGCAA GACTTTGTTC TGCTGGAGAA CTTCACCAGT 
GAGGCTGCCT TCATTGAGAA CCTCCGGCGT CGATTCCGGG AGAACCTCAT TTATACCTAC 
ATTGGCCCTG TCCTGGTCTC TGTCAACCCC TACCGGGACC TACAGATCTA CACACGGCAA 
CATATGGAAC GCTACCGTGG CGTCAGTTTC TATGAAGTGC CGCCTCATCT GTTTGCAGTG 
GCTGACACTG TATACCGGGC GCTTCGTACT GAGCGTCGGG ACCAAGCAGT GATGATTTCT 
GGAGAGAGTG GGGCAGGGAA GACAGAGGCC ACCAAGAGAT TGCTCCAGTT CTATGCAGAG 
ACCTGCCCAG CCCCTGAAAG GGGTGGCGCA GTGCGAGACC GCCTGTTGCA GAGCAACCCT 
GTGCTGGAGG CCTTTGGGAA TGCCAAGACT CTCCGCAACG ACAACTCCAG CCGCTTTGGG 
AAGTACATGG ATGTGCAGTT TGACTTCAAG GGTGCCCCTG TGGGAGGCCA CATTCTCAGT 
TACCTCCTGG AGAAGTCTCG AGTGGTACAC CAGAATCACG GAGAACGGAA CTTCCACGTC 
TTTTACCAGC TCCTGGAGGG GGGGGAGGAG GAGGCTCTTC GTCGTCTGGG CTTGGAACGG 
AACCCCCAGA GCTACTTGTA CCTGGTGAAG GGCCAGTGTG CCAAGGTCTC CTCCATCAAT 
GACAAGAGTG ACTGGAAGGT TGTGAGGAAG GCGCTGTCAG TCATTGACTT CACTGAGGAT 
GAAGTGGAGG ACTTGCTAAG CATCGTGGCC AGCGTCCTAC ATCTGGGCAA TATCCACTTT 
GCTGCTGATG AGGACAGCAA TGCCCAGGTT ACTACTGAGA ACCAGCTCAA ATATCTGACC 
AGGCTCCTTG GTGTGGAAGG CACAACACTG AGGGAAGCCC TGACCCACAG GAAGATCATC 
GCCAAGGGGG AAGAGCTCCT GAGCCCACTG AACCTTGAAC AGGCTGCATA TGCAAGGGAT 
GCTCTTGCCA AGGCTGTGTA CAGCCGCACT TTCACCTGGT TGGTCAGAAA GATCAATAGG 
TCTCTGGCCT CTAAGGACGC TGAGAGCCCC AGCTGGCGAA GCACCACAGT TCTTGGGCTC 
CTGGACATTT ATGGCTTCGA AGTGTTTCAG CATAACAGCT TCGAGCAGTT CTGCATCAAC 
TATTGCAATG AGAAGCTGCA GCAGCTCTTC ATTGAGCTGA CTCTCAAGTC CGAGCAGGAG 
GAATACGAGG CAGAGGGCAT CGCGTGGGAA CCTGTCCAAT ACTTCAACAA CAAGATCATC 
TGTGACCTGG TGGAGGAGAA ATTCAAGGGC ATCATCTCCA TCTTGGATGA AGAGTGCCTG 
CGTCCTGGGG AGGCCACAGA CCTGACCTTC CTGGAGAAGC TGGAGGACAC AATCAAGCAC 
CACCCTCACT TCCTGACGCA CAAGCTTGCT GACCAGAAGA CCAGGAAATC CCTCGACCGA 
GGGGAGTTCC GCCTTCTTCA TTATGCGGGA GAGGTGACCT ACAGCGTGAC TGGGTTTCTG 
GATAAAAACA ATGACCTCCT CTTCCGGAAC CTGAAGGAGA CCATGTGCAG CTCCACGAAC 
CCCATCATGG CCCAGTGCTT TGACAAGAGT GAGCTCAGTG ACAAGAAGCG GCCAGAGACG 
GTGGCCACCC AGTTCAAGAT GAGCCTCTTG CAGCTAGTGG AGATCCTGAG GTCTAAGGAA 
CCTGCTTATA TCCGGTGCAT CAAGCCAAAT GACGCCAAAC AGCCGGGTCG CTTTGATGAG 
GTGCTCATCC GACACCAAGT GAAGTACCTG GGACTTATGG AGAATCTGCG TGTGCGCAGA 
GCTGGCTTTG CCTACCGTCG AAAATATGAG GCTTTCCTGC AGAGGTACAA GTCACTGTGC 
CCAGAGACAT GGCCCGTGTG GACAGGACGG CCCCAGGATG GGGTGGCTGT GTTGGTCAGA 
CACCTTGGCT ATAAGCCAGA AGAGTACAAA ATGGGCAGGA CTAAGATCTT CATCCGATTC 
CCCAAGACCT TGTTTGCCAC AGAGGACTCC CTGGAAGTCC GACGGCAGAG TCTAGCCACC 
AAGATCCAGG CGGCGTGGAG GGGCTTTCAT TGGCGGCAGA AATTTCTCCG GGTGAAGCGA 
TCAGCCATCT GTATCCAGTC CTGGTGGCGC GGTACACTGG GCCGGAGGAA GGCAGCCAAA 
AGGAAGTGGG CAGCCCAGAC TATCCGTAGA CTCATCCGTG GCTTCATTTT GCGTCATGCA 
CCCCGGTGCC CTGAGAATGC CTTCTTCCTG GACCACGTGC GCACGTCATT TTTGCTTAAC 
CTGAGGCGAC AACTACCCCG GAATGTTCTG GACACCTCCT GGCCCACACC CCCACCTGCC 
CTGAGAGAGG CCTCGGAGCT GCTCCGGGAG CTATGCATGA AGAACATGGT GTGGAAATAC 
TGCCGGAGTA TCAGCCCTGA GTGGAAGCAG CAGCTGCAGC AAAAGGCGGT GGCTAGTGAA 
ATTTTCAAGG GCAAGAAGGA CAATTACCCC CAGAGTGTCC CCAGACTTTT CATCAGCACA 
CGGCTTGGCA CAGAGGAGAT CAGCCCCAGA GTGCTTCAGG CCTTGGGCTC TGAACCCATC 
CAGTATGCAG TGCCTGTGGT AAAATACGAC CGTAAGGGCT ACAAGCCTCG TTCCCGGCAG 
CTGCTGCTCA CACCCAGTGC TGTGGTCATC GTGGAGGATG CCAAAGTCAA GCAGAGAATT 
GATTATGCCA ACCTAACTGG AATCTCCGTC AGTAGCCTGA GTGATAGCCT GTTTGTGCTT 
CACGTGCAGC GTGAAGACAG CAAGCAGAAG GGAGATGTGG TACTGCAGAG CGATCATGTG 
ATCGAGACAC TAACCAAGAC GGCCCTCAGT GCTGACCGTG TGAATAATAT CAACATCAAC 
CAGGGCAGCA TCACGTTTGC AGGGGGTCCA GGCAGGGATG GCATCATCGA CTTCACATCT 
GGCTCAGAGC TTCTCATCAC CAAGGCTAAG AATGGCCACC TGGCTGTGGT GGCCCCACGG 
CTGAATTCTC GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The role of myosin 1c and myosin 1b in surfactant exocytosis.
Journal of cell science129(8)1685-96(2016 Apr)
Kittelberger N,Breunig M,Martin R,Knölker HJ,Miklavc P

Rho GTPases in insulin-stimulated glucose uptake.
Small GTPases5e28102(2014)
Satoh T

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.
Nature cell biology15(10)1220-30(2013 Oct)
Simicek M,Lievens S,Laga M,Guzenko D,Aushev VN,Kalev P,Baietti MF,Strelkov SV,Gevaert K,Tavernier J,Sablina AA

The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling.
American journal of physiology. Heart and circulatory physiology304(5)H687-96(2013 Mar)
Tiwari A,Jung JJ,Inamdar SM,Nihalani D,Choudhury A

Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles.
Molecular biology of the cell23(20)4065-78(2012 Oct)
Boguslavsky S,Chiu T,Foley KP,Osorio-Fuentealba C,Antonescu CN,Bayer KU,Bilan PJ,Klip A

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Myo1c cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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